Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation by symbiont of host defense response (GO:0052509) | 6.58647118 |
2 | modulation by symbiont of host defense response (GO:0052031) | 6.58647118 |
3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.58647118 |
4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.58647118 |
5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.58647118 |
6 | modulation by symbiont of host immune response (GO:0052553) | 6.58647118 |
7 | regulation of interferon-beta biosynthetic process (GO:0045357) | 5.96338895 |
8 | neutrophil activation involved in immune response (GO:0002283) | 5.22800367 |
9 | macrophage activation involved in immune response (GO:0002281) | 5.21943183 |
10 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.80688409 |
11 | microglial cell activation (GO:0001774) | 4.45846353 |
12 | positive regulation of interferon-alpha production (GO:0032727) | 4.43149890 |
13 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 4.26469092 |
14 | mannose metabolic process (GO:0006013) | 4.19082624 |
15 | regulation of interferon-alpha production (GO:0032647) | 4.17502335 |
16 | response to host immune response (GO:0052572) | 4.05240566 |
17 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.05240566 |
18 | immunoglobulin mediated immune response (GO:0016064) | 3.91466696 |
19 | response to peptidoglycan (GO:0032494) | 3.87049398 |
20 | macrophage activation (GO:0042116) | 3.79639843 |
21 | respiratory burst (GO:0045730) | 3.73163678 |
22 | pinocytosis (GO:0006907) | 3.70699837 |
23 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.67317560 |
24 | positive regulation of antigen processing and presentation (GO:0002579) | 3.64461872 |
25 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.64128396 |
26 | response to host (GO:0075136) | 3.60317202 |
27 | response to host defenses (GO:0052200) | 3.60317202 |
28 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.60317202 |
29 | oligosaccharide catabolic process (GO:0009313) | 3.47112577 |
30 | myeloid cell activation involved in immune response (GO:0002275) | 3.44780476 |
31 | apoptotic cell clearance (GO:0043277) | 3.42429637 |
32 | regulation of mononuclear cell migration (GO:0071675) | 3.39583300 |
33 | keratan sulfate catabolic process (GO:0042340) | 3.37505954 |
34 | barbed-end actin filament capping (GO:0051016) | 3.30569705 |
35 | detection of molecule of bacterial origin (GO:0032490) | 3.29078962 |
36 | positive regulation of interferon-beta production (GO:0032728) | 3.25989158 |
37 | regulation of cholesterol storage (GO:0010885) | 3.21544436 |
38 | regulation of antigen processing and presentation (GO:0002577) | 3.16475322 |
39 | amyloid precursor protein catabolic process (GO:0042987) | 3.14317504 |
40 | glycosphingolipid catabolic process (GO:0046479) | 3.10957900 |
41 | hyaluronan catabolic process (GO:0030214) | 3.10884415 |
42 | granulocyte activation (GO:0036230) | 3.09291452 |
43 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.09021984 |
44 | peptide catabolic process (GO:0043171) | 3.07124765 |
45 | negative regulation of mast cell activation (GO:0033004) | 3.07015016 |
46 | neutrophil activation (GO:0042119) | 3.06681583 |
47 | ceramide catabolic process (GO:0046514) | 3.02087454 |
48 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.01658118 |
49 | response to thyroid hormone (GO:0097066) | 2.99415329 |
50 | regulation of mast cell degranulation (GO:0043304) | 2.97211175 |
51 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.92988352 |
52 | protein localization to endosome (GO:0036010) | 2.90992008 |
53 | positive regulation of mast cell activation (GO:0033005) | 2.90979820 |
54 | positive regulation of receptor recycling (GO:0001921) | 2.87569666 |
55 | low-density lipoprotein particle remodeling (GO:0034374) | 2.86817963 |
56 | folic acid transport (GO:0015884) | 2.86762798 |
57 | amino sugar catabolic process (GO:0046348) | 2.86107633 |
58 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.84996820 |
59 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.84565897 |
60 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.84328957 |
61 | regulation of platelet activation (GO:0010543) | 2.83442271 |
62 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.82437411 |
63 | glycolipid catabolic process (GO:0019377) | 2.81781335 |
64 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.81525125 |
65 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.81491614 |
66 | I-kappaB phosphorylation (GO:0007252) | 2.80499650 |
67 | adenosine receptor signaling pathway (GO:0001973) | 2.78363682 |
68 | leukotriene metabolic process (GO:0006691) | 2.76815561 |
69 | regulation of mast cell activation (GO:0033003) | 2.74788310 |
70 | adhesion of symbiont to host cell (GO:0044650) | 2.73800847 |
71 | virion attachment to host cell (GO:0019062) | 2.73800847 |
72 | negative regulation of platelet activation (GO:0010544) | 2.72203598 |
73 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.71180735 |
74 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.70119628 |
75 | positive regulation of leukocyte degranulation (GO:0043302) | 2.69867882 |
76 | platelet degranulation (GO:0002576) | 2.68435204 |
77 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.68089252 |
78 | angiogenesis involved in wound healing (GO:0060055) | 2.67896930 |
79 | negative regulation of interleukin-6 production (GO:0032715) | 2.67764005 |
80 | low-density lipoprotein particle clearance (GO:0034383) | 2.66403287 |
81 | regulation of macrophage chemotaxis (GO:0010758) | 2.65771216 |
82 | regulation of early endosome to late endosome transport (GO:2000641) | 2.65746415 |
83 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.64074162 |
84 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.63783362 |
85 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.63739464 |
86 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 2.63610273 |
87 | negative regulation of interleukin-12 production (GO:0032695) | 2.62260605 |
88 | positive regulation of macrophage differentiation (GO:0045651) | 2.61765018 |
89 | B cell mediated immunity (GO:0019724) | 2.61714076 |
90 | cellular extravasation (GO:0045123) | 2.60819580 |
91 | fibril organization (GO:0097435) | 2.59784900 |
92 | positive regulation of B cell differentiation (GO:0045579) | 2.59672722 |
93 | sphingolipid catabolic process (GO:0030149) | 2.59579420 |
94 | membrane lipid catabolic process (GO:0046466) | 2.59561344 |
95 | regulation of superoxide anion generation (GO:0032928) | 2.59365460 |
96 | regulation of leukocyte degranulation (GO:0043300) | 2.59157860 |
97 | regulation of cholesterol esterification (GO:0010872) | 2.58756094 |
98 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.58732308 |
99 | response to lipoprotein particle (GO:0055094) | 2.58195968 |
100 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.57539194 |
101 | myeloid leukocyte activation (GO:0002274) | 2.56161114 |
102 | positive regulation of extracellular matrix organization (GO:1903055) | 2.55859748 |
103 | response to muramyl dipeptide (GO:0032495) | 2.55761858 |
104 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.55550004 |
105 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.55121157 |
106 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.55093398 |
107 | response to laminar fluid shear stress (GO:0034616) | 2.54409843 |
108 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.54136879 |
109 | regulation of interferon-beta production (GO:0032648) | 2.54075007 |
110 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.53911570 |
111 | adhesion of symbiont to host (GO:0044406) | 2.53641786 |
112 | lymphocyte chemotaxis (GO:0048247) | 2.52964093 |
113 | regulation of platelet aggregation (GO:0090330) | 2.52638586 |
114 | glycosylceramide metabolic process (GO:0006677) | 2.52607630 |
115 | phagosome maturation (GO:0090382) | 2.52409842 |
116 | N-acetylneuraminate metabolic process (GO:0006054) | 2.52145082 |
117 | negative regulation of lipid storage (GO:0010888) | 2.52143752 |
118 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.51404063 |
119 | platelet aggregation (GO:0070527) | 2.51025400 |
120 | negative regulation of protein localization to plasma membrane (GO:1903077) | 2.50481034 |
121 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.49646020 |
122 | phagocytosis, engulfment (GO:0006911) | 2.49409903 |
123 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.49316024 |
124 | thrombin receptor signaling pathway (GO:0070493) | 2.49215684 |
125 | cyclooxygenase pathway (GO:0019371) | 2.48872056 |
126 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.47938180 |
127 | regulation of extracellular matrix disassembly (GO:0010715) | 2.47361385 |
128 | leukocyte mediated cytotoxicity (GO:0001909) | 2.47267015 |
129 | negative regulation of interleukin-17 production (GO:0032700) | 2.47059803 |
130 | regulation of monocyte chemotaxis (GO:0090025) | 2.46399438 |
131 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 2.46184754 |
132 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.46104565 |
133 | cytidine metabolic process (GO:0046087) | 2.45932922 |
134 | cytidine catabolic process (GO:0006216) | 2.45932922 |
135 | cytidine deamination (GO:0009972) | 2.45932922 |
136 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.45843646 |
137 | regulation of integrin activation (GO:0033623) | 2.44762080 |
138 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.43467236 |
139 | lipoxygenase pathway (GO:0019372) | 2.43401315 |
140 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 2.42269858 |
141 | fibrinolysis (GO:0042730) | 2.42025627 |
142 | negative regulation of cell killing (GO:0031342) | 2.41447540 |
143 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.41447540 |
144 | stress fiber assembly (GO:0043149) | 2.40943493 |
145 | extracellular fibril organization (GO:0043206) | 2.39211693 |
146 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.38734907 |
147 | positive regulation of coagulation (GO:0050820) | 2.36465149 |
148 | positive regulation of blood coagulation (GO:0030194) | 2.34688170 |
149 | positive regulation of hemostasis (GO:1900048) | 2.34688170 |
150 | blood coagulation, intrinsic pathway (GO:0007597) | 2.30599786 |
151 | myeloid dendritic cell differentiation (GO:0043011) | 2.29144728 |
152 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.28374779 |
153 | regulation of podosome assembly (GO:0071801) | 2.28032916 |
154 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.27348642 |
155 | lytic vacuole organization (GO:0080171) | 2.27112989 |
156 | lysosome organization (GO:0007040) | 2.27112989 |
157 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.26793557 |
158 | skin morphogenesis (GO:0043589) | 2.24752706 |
159 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.22984319 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.96989816 |
2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.83280971 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.61807098 |
4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.96809356 |
5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.77084242 |
6 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.32434761 |
7 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 3.24536323 |
8 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.09272725 |
9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.75043701 |
10 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.51211816 |
11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.45381374 |
12 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.32975970 |
13 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.14232701 |
14 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.12937580 |
15 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.10096396 |
16 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.08678851 |
17 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.07132986 |
18 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.94656163 |
19 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.85166437 |
20 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.82694644 |
21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.76673620 |
22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.72856537 |
23 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.72362930 |
24 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.69161997 |
25 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.69122570 |
26 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.67711533 |
27 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.67338986 |
28 | SPI1_23127762_ChIP-Seq_K562_Human | 1.67120831 |
29 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.67088229 |
30 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.66283749 |
31 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.65885650 |
32 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.63502088 |
33 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.60804072 |
34 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.59364641 |
35 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.59153874 |
36 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.58691342 |
37 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.58494357 |
38 | GATA1_19941826_ChIP-Seq_K562_Human | 1.57452205 |
39 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.57431671 |
40 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.56904687 |
41 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.56656929 |
42 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.56187496 |
43 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.53791327 |
44 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.50749584 |
45 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.50656444 |
46 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49157571 |
47 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.47986519 |
48 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.47313829 |
49 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.42826243 |
50 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.42602764 |
51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.42227700 |
52 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.41852836 |
53 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.41061175 |
54 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.39766872 |
55 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.37777057 |
56 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.37357456 |
57 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36532406 |
58 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.33974997 |
59 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.32941639 |
60 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.32762312 |
61 | MAF_26560356_Chip-Seq_TH1_Human | 1.32399164 |
62 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.31284758 |
63 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.30882939 |
64 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.30683866 |
65 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.28530923 |
66 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.28310607 |
67 | GATA1_22025678_ChIP-Seq_K562_Human | 1.27557010 |
68 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27397421 |
69 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.26180851 |
70 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.24392656 |
71 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.23144359 |
72 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22425055 |
73 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.21106706 |
74 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.20992713 |
75 | GATA2_19941826_ChIP-Seq_K562_Human | 1.18036052 |
76 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.17152383 |
77 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.15073884 |
78 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.14347181 |
79 | MYB_26560356_Chip-Seq_TH2_Human | 1.13808906 |
80 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.12428764 |
81 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.12296213 |
82 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09886911 |
83 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.08724188 |
84 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.07115382 |
85 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06435641 |
86 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05861138 |
87 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.05044058 |
88 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.04396741 |
89 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.04241110 |
90 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.04100130 |
91 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03983696 |
92 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.03982540 |
93 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.03582460 |
94 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.03492993 |
95 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.03186955 |
96 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.02993948 |
97 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.02792068 |
98 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.02657119 |
99 | MYB_26560356_Chip-Seq_TH1_Human | 1.02419941 |
100 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01719077 |
101 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.01465882 |
102 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.01349135 |
103 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.99600842 |
104 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.98983735 |
105 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.98390656 |
106 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.97878514 |
107 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.96177192 |
108 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.95439571 |
109 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94997210 |
110 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.94106147 |
111 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.93937293 |
112 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.92737226 |
113 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.91750804 |
114 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.91396468 |
115 | UTX_26944678_Chip-Seq_JUKART_Human | 0.90603560 |
116 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.90042290 |
117 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89960521 |
118 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.89198988 |
119 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.88331749 |
120 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.87756814 |
121 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.87682774 |
122 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.87177043 |
123 | GATA3_26560356_Chip-Seq_TH2_Human | 0.86793973 |
124 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85711749 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MP0005058_abnormal_lysosome_morphology | 5.58876032 |
2 | MP0009840_abnormal_foam_cell | 4.03630107 |
3 | MP0003172_abnormal_lysosome_physiology | 3.29908944 |
4 | MP0001835_abnormal_antigen_presentation | 3.17889554 |
5 | MP0006082_CNS_inflammation | 3.01224878 |
6 | MP0008438_abnormal_cutaneous_collagen | 2.97282052 |
7 | MP0003191_abnormal_cellular_cholesterol | 2.94705474 |
8 | MP0003436_decreased_susceptibility_to | 2.84735932 |
9 | MP0002419_abnormal_innate_immunity | 2.74920468 |
10 | MP0003303_peritoneal_inflammation | 2.47221024 |
11 | MP0002148_abnormal_hypersensitivity_rea | 2.37506228 |
12 | MP0002139_abnormal_hepatobiliary_system | 2.32003789 |
13 | MP0005000_abnormal_immune_tolerance | 2.20814322 |
14 | MP0000604_amyloidosis | 2.13476156 |
15 | MP0008004_abnormal_stomach_pH | 2.08012432 |
16 | MP0001533_abnormal_skeleton_physiology | 2.04180535 |
17 | MP0005025_abnormal_response_to | 2.02577119 |
18 | MP0005257_abnormal_intraocular_pressure | 2.01248114 |
19 | MP0009785_altered_susceptibility_to | 1.98913386 |
20 | MP0002452_abnormal_antigen_presenting | 1.96257275 |
21 | MP0002877_abnormal_melanocyte_morpholog | 1.96143570 |
22 | MP0006054_spinal_hemorrhage | 1.94422392 |
23 | MP0003690_abnormal_glial_cell | 1.94017900 |
24 | MP0001790_abnormal_immune_system | 1.92613858 |
25 | MP0005387_immune_system_phenotype | 1.92613858 |
26 | MP0005464_abnormal_platelet_physiology | 1.89074126 |
27 | MP0004510_myositis | 1.81032325 |
28 | MP0000343_altered_response_to | 1.73650878 |
29 | MP0003724_increased_susceptibility_to | 1.72071825 |
30 | MP0002723_abnormal_immune_serum | 1.71767771 |
31 | MP0005671_abnormal_response_to | 1.70551186 |
32 | MP0001800_abnormal_humoral_immune | 1.64697766 |
33 | MP0009333_abnormal_splenocyte_physiolog | 1.64086234 |
34 | MP0000685_abnormal_immune_system | 1.57174908 |
35 | MP0005365_abnormal_bile_salt | 1.54082901 |
36 | MP0001819_abnormal_immune_cell | 1.52876321 |
37 | MP0003448_altered_tumor_morphology | 1.52045829 |
38 | MP0008469_abnormal_protein_level | 1.52019099 |
39 | MP0002420_abnormal_adaptive_immunity | 1.51762770 |
40 | MP0003566_abnormal_cell_adhesion | 1.51685950 |
41 | MP0002405_respiratory_system_inflammati | 1.51203928 |
42 | MP0002998_abnormal_bone_remodeling | 1.47052102 |
43 | MP0003279_aneurysm | 1.44811297 |
44 | MP0001958_emphysema | 1.44429832 |
45 | MP0001845_abnormal_inflammatory_respons | 1.44166286 |
46 | MP0008260_abnormal_autophagy | 1.41341350 |
47 | MP0003300_gastrointestinal_ulcer | 1.40471045 |
48 | MP0004947_skin_inflammation | 1.39944910 |
49 | MP0003075_altered_response_to | 1.39563249 |
50 | MP0001542_abnormal_bone_strength | 1.34903087 |
51 | MP0003705_abnormal_hypodermis_morpholog | 1.33469783 |
52 | MP0001853_heart_inflammation | 1.32690858 |
53 | MP0003806_abnormal_nucleotide_metabolis | 1.31291881 |
54 | MP0005310_abnormal_salivary_gland | 1.20383121 |
55 | MP0000465_gastrointestinal_hemorrhage | 1.19893624 |
56 | MP0003091_abnormal_cell_migration | 1.18829258 |
57 | MP0002933_joint_inflammation | 1.16783135 |
58 | MP0005390_skeleton_phenotype | 1.16509208 |
59 | MP0009764_decreased_sensitivity_to | 1.15032378 |
60 | MP0010307_abnormal_tumor_latency | 1.14721449 |
61 | MP0000858_altered_metastatic_potential | 1.13507589 |
62 | MP0005166_decreased_susceptibility_to | 1.09978517 |
63 | MP0003186_abnormal_redox_activity | 1.09395852 |
64 | MP0000716_abnormal_immune_system | 1.08206762 |
65 | MP0005023_abnormal_wound_healing | 1.07184128 |
66 | MP0003329_amyloid_beta_deposits | 1.05602867 |
67 | MP0003183_abnormal_peptide_metabolism | 1.04818226 |
68 | * MP0000689_abnormal_spleen_morphology | 1.03137272 |
69 | MP0009278_abnormal_bone_marrow | 1.02970343 |
70 | MP0009643_abnormal_urine_homeostasis | 1.01775960 |
71 | MP0003828_pulmonary_edema | 0.98141203 |
72 | MP0005275_abnormal_skin_tensile | 0.96343845 |
73 | MP0010155_abnormal_intestine_physiology | 0.96048994 |
74 | MP0004272_abnormal_basement_membrane | 0.95887592 |
75 | MP0003656_abnormal_erythrocyte_physiolo | 0.95763224 |
76 | MP0005451_abnormal_body_composition | 0.95596471 |
77 | MP0000920_abnormal_myelination | 0.93921266 |
78 | MP0004019_abnormal_vitamin_homeostasis | 0.92144966 |
79 | MP0005164_abnormal_response_to | 0.91277995 |
80 | MP0000249_abnormal_blood_vessel | 0.91106464 |
81 | * MP0002136_abnormal_kidney_physiology | 0.90860674 |
82 | MP0005083_abnormal_biliary_tract | 0.90121732 |
83 | MP0003795_abnormal_bone_structure | 0.89677770 |
84 | MP0002429_abnormal_blood_cell | 0.89497473 |
85 | MP0001851_eye_inflammation | 0.88171446 |
86 | MP0000609_abnormal_liver_physiology | 0.87411608 |
87 | MP0002295_abnormal_pulmonary_circulatio | 0.85778423 |
88 | MP0005670_abnormal_white_adipose | 0.85313478 |
89 | MP0003195_calcinosis | 0.84040371 |
90 | * MP0002722_abnormal_immune_system | 0.83604271 |
91 | MP0001849_ear_inflammation | 0.83193721 |
92 | MP0003879_abnormal_hair_cell | 0.83112423 |
93 | MP0005408_hypopigmentation | 0.82714076 |
94 | MP0002398_abnormal_bone_marrow | 0.82262531 |
95 | MP0009763_increased_sensitivity_to | 0.80546652 |
96 | MP0005332_abnormal_amino_acid | 0.79657727 |
97 | MP0004883_abnormal_blood_vessel | 0.79196626 |
98 | MP0005165_increased_susceptibility_to | 0.78760115 |
99 | MP0005167_abnormal_blood-brain_barrier | 0.78311789 |
100 | MP0001663_abnormal_digestive_system | 0.77275992 |
101 | * MP0001756_abnormal_urination | 0.77227625 |
102 | MP0000015_abnormal_ear_pigmentation | 0.77195081 |
103 | MP0004782_abnormal_surfactant_physiolog | 0.77036674 |
104 | MP0005360_urolithiasis | 0.76724756 |
105 | MP0005319_abnormal_enzyme/_coenzyme | 0.75132439 |
106 | MP0000767_abnormal_smooth_muscle | 0.74814688 |
107 | MP0003950_abnormal_plasma_membrane | 0.73232683 |
108 | MP0002118_abnormal_lipid_homeostasis | 0.72961591 |
109 | MP0002090_abnormal_vision | 0.71725458 |
110 | MP0010329_abnormal_lipoprotein_level | 0.71616413 |
111 | MP0001545_abnormal_hematopoietic_system | 0.70941444 |
112 | MP0005397_hematopoietic_system_phenotyp | 0.70941444 |
113 | MP0000569_abnormal_digit_pigmentation | 0.70861221 |
114 | MP0000371_diluted_coat_color | 0.68968184 |
115 | MP0001243_abnormal_dermal_layer | 0.68948906 |
116 | MP0002254_reproductive_system_inflammat | 0.68759731 |
117 | MP0003453_abnormal_keratinocyte_physiol | 0.68204676 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Vacuolated lymphocytes (HP:0001922) | 6.60278095 |
2 | Systemic lupus erythematosus (HP:0002725) | 6.27215422 |
3 | Increased cerebral lipofuscin (HP:0011813) | 6.05357530 |
4 | Recurrent abscess formation (HP:0002722) | 5.75755681 |
5 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 5.42920648 |
6 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.17288952 |
7 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.17288952 |
8 | Abnormality of glycolipid metabolism (HP:0010969) | 5.17288952 |
9 | Recurrent bacterial skin infections (HP:0005406) | 5.09468050 |
10 | * Dysostosis multiplex (HP:0000943) | 4.96940448 |
11 | Eczematoid dermatitis (HP:0000976) | 4.59899505 |
12 | Mucopolysacchariduria (HP:0008155) | 4.46009390 |
13 | Urinary glycosaminoglycan excretion (HP:0003541) | 4.46009390 |
14 | Abnormality of macrophages (HP:0004311) | 4.44961634 |
15 | Glomerulonephritis (HP:0000099) | 4.44196513 |
16 | Axonal loss (HP:0003447) | 4.32888705 |
17 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 4.20611904 |
18 | Abnormality of polysaccharide metabolism (HP:0011012) | 4.20611904 |
19 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 4.20611904 |
20 | Prolonged bleeding time (HP:0003010) | 4.14572303 |
21 | Menorrhagia (HP:0000132) | 4.07514498 |
22 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.03842681 |
23 | Increased mean platelet volume (HP:0011877) | 3.52544067 |
24 | Epistaxis (HP:0000421) | 3.52070363 |
25 | Gingival bleeding (HP:0000225) | 3.51037426 |
26 | Abnormal platelet volume (HP:0011876) | 3.48339200 |
27 | Osteolytic defects of the hand bones (HP:0009699) | 3.40321880 |
28 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 3.40321880 |
29 | Complement deficiency (HP:0004431) | 3.35200584 |
30 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 3.27305362 |
31 | Pustule (HP:0200039) | 3.20556086 |
32 | Abnormality of complement system (HP:0005339) | 3.19774309 |
33 | Disinhibition (HP:0000734) | 3.15362818 |
34 | Premature rupture of membranes (HP:0001788) | 3.08203625 |
35 | Asymmetric septal hypertrophy (HP:0001670) | 2.92306666 |
36 | Recurrent skin infections (HP:0001581) | 2.90339041 |
37 | Gingivitis (HP:0000230) | 2.89679850 |
38 | Loss of speech (HP:0002371) | 2.89469864 |
39 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.87891149 |
40 | Myocardial infarction (HP:0001658) | 2.80947165 |
41 | Nuclear cataract (HP:0100018) | 2.78913176 |
42 | Neurofibrillary tangles (HP:0002185) | 2.74670115 |
43 | Nephritis (HP:0000123) | 2.65162527 |
44 | Abnormal platelet function (HP:0011869) | 2.64408875 |
45 | Impaired platelet aggregation (HP:0003540) | 2.64408875 |
46 | Chronic obstructive pulmonary disease (HP:0006510) | 2.61532284 |
47 | Obstructive lung disease (HP:0006536) | 2.61532284 |
48 | Thick nail (HP:0001805) | 2.60608457 |
49 | Vertebral compression fractures (HP:0002953) | 2.56005215 |
50 | Petechiae (HP:0000967) | 2.50273682 |
51 | Autoimmune thrombocytopenia (HP:0001973) | 2.49513062 |
52 | Protrusio acetabuli (HP:0003179) | 2.49249388 |
53 | Increased serum ferritin (HP:0003281) | 2.47749863 |
54 | Personality changes (HP:0000751) | 2.47185976 |
55 | Pathologic fracture (HP:0002756) | 2.45740893 |
56 | Cervical subluxation (HP:0003308) | 2.41880949 |
57 | Mediastinal lymphadenopathy (HP:0100721) | 2.38377321 |
58 | Progressive neurologic deterioration (HP:0002344) | 2.36286681 |
59 | Ovoid vertebral bodies (HP:0003300) | 2.35745797 |
60 | Spondylolisthesis (HP:0003302) | 2.32511322 |
61 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.32466743 |
62 | Abnormality of the common coagulation pathway (HP:0010990) | 2.31709218 |
63 | Global brain atrophy (HP:0002283) | 2.29194841 |
64 | Hyperlipoproteinemia (HP:0010980) | 2.27705912 |
65 | Myositis (HP:0100614) | 2.25725711 |
66 | Interstitial pulmonary disease (HP:0006530) | 2.25712942 |
67 | Agnosia (HP:0010524) | 2.23876374 |
68 | Deep venous thrombosis (HP:0002625) | 2.22215537 |
69 | * Hepatosplenomegaly (HP:0001433) | 2.21206944 |
70 | Mitral stenosis (HP:0001718) | 2.19709087 |
71 | Periodontitis (HP:0000704) | 2.19413545 |
72 | Retinal atrophy (HP:0001105) | 2.19098899 |
73 | Cerebral aneurysm (HP:0004944) | 2.17712275 |
74 | Prolonged neonatal jaundice (HP:0006579) | 2.15746370 |
75 | Peripheral demyelination (HP:0011096) | 2.15440958 |
76 | Abnormality of iron homeostasis (HP:0011031) | 2.15308673 |
77 | Recurrent fungal infections (HP:0002841) | 2.15050468 |
78 | Joint stiffness (HP:0001387) | 2.14533946 |
79 | Thoracic kyphosis (HP:0002942) | 2.11819464 |
80 | Stomatitis (HP:0010280) | 2.10877043 |
81 | Abnormality of the Achilles tendon (HP:0005109) | 2.10771734 |
82 | Upper motor neuron abnormality (HP:0002127) | 2.10607634 |
83 | Basal ganglia calcification (HP:0002135) | 2.10589615 |
84 | Abnormality of the lumbar spine (HP:0100712) | 2.09565149 |
85 | Progressive visual loss (HP:0000529) | 2.09479211 |
86 | Spontaneous hematomas (HP:0007420) | 2.04186888 |
87 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.01342542 |
88 | J-shaped sella turcica (HP:0002680) | 2.01302847 |
89 | Bruising susceptibility (HP:0000978) | 2.00304787 |
90 | Mutism (HP:0002300) | 1.97745108 |
91 | Beaking of vertebral bodies (HP:0004568) | 1.95965394 |
92 | Neuronal loss in central nervous system (HP:0002529) | 1.91493523 |
93 | Orchitis (HP:0100796) | 1.91484817 |
94 | Hemorrhage of the eye (HP:0011885) | 1.90493452 |
95 | Cerebral inclusion bodies (HP:0100314) | 1.88827907 |
96 | Xanthomatosis (HP:0000991) | 1.88178572 |
97 | Vascular calcification (HP:0004934) | 1.87307026 |
98 | Bone pain (HP:0002653) | 1.86657152 |
99 | Cardiovascular calcification (HP:0011915) | 1.85559639 |
100 | Distal lower limb muscle weakness (HP:0009053) | 1.84210056 |
101 | Prostate neoplasm (HP:0100787) | 1.83261952 |
102 | Osteomyelitis (HP:0002754) | 1.83071035 |
103 | Arterial tortuosity (HP:0005116) | 1.82541634 |
104 | Diminished motivation (HP:0000745) | 1.81716474 |
105 | Hematochezia (HP:0002573) | 1.80802472 |
106 | Urticaria (HP:0001025) | 1.80482113 |
107 | Achilles tendon contracture (HP:0001771) | 1.79484589 |
108 | Purpura (HP:0000979) | 1.79216310 |
109 | Polycythemia (HP:0001901) | 1.78847640 |
110 | Apathy (HP:0000741) | 1.78792376 |
111 | Vascular tortuosity (HP:0004948) | 1.78438107 |
112 | Poor head control (HP:0002421) | 1.78272712 |
113 | Nausea (HP:0002018) | 1.78153395 |
114 | Recurrent viral infections (HP:0004429) | 1.77179262 |
115 | Cellulitis (HP:0100658) | 1.77058119 |
116 | Cardiomegaly (HP:0001640) | 1.77020077 |
117 | Leukocytosis (HP:0001974) | 1.71431081 |
118 | Joint hemorrhage (HP:0005261) | 1.70319551 |
119 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.69817098 |
120 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.69441835 |
121 | Joint swelling (HP:0001386) | 1.68546800 |
122 | Supranuclear gaze palsy (HP:0000605) | 1.68034041 |
123 | Premature loss of primary teeth (HP:0006323) | 1.67766484 |
124 | Recurrent pneumonia (HP:0006532) | 1.67349668 |
125 | Distal lower limb amyotrophy (HP:0008944) | 1.67026399 |
126 | Hypertriglyceridemia (HP:0002155) | 1.67011898 |
127 | Optic neuritis (HP:0100653) | 1.65072479 |
128 | Retrobulbar optic neuritis (HP:0100654) | 1.65072479 |
129 | Pulmonary infiltrates (HP:0002113) | 1.64106421 |
130 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.63106887 |
131 | Peritonitis (HP:0002586) | 1.61828539 |
132 | Amyloidosis (HP:0011034) | 1.59065365 |
133 | Aortic dissection (HP:0002647) | 1.57665838 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TGFBR2 | 3.96102481 |
2 | BLK | 3.79164579 |
3 | IRAK3 | 3.03454933 |
4 | ERN1 | 3.00735338 |
5 | TYK2 | 2.81839129 |
6 | TBK1 | 2.76962327 |
7 | KIT | 2.67061282 |
8 | TAOK3 | 2.61398538 |
9 | MAP4K1 | 2.50523254 |
10 | CSF1R | 2.29739715 |
11 | IRAK4 | 2.20994779 |
12 | TAOK2 | 2.15732102 |
13 | TESK1 | 2.04694965 |
14 | EPHB1 | 1.99376433 |
15 | STK10 | 1.93809995 |
16 | MYLK | 1.92281504 |
17 | RIPK4 | 1.85820850 |
18 | TRIB3 | 1.84963250 |
19 | MAP3K14 | 1.83633443 |
20 | NME2 | 1.75540583 |
21 | PRPF4B | 1.68933076 |
22 | NEK9 | 1.68843692 |
23 | PIM2 | 1.68660384 |
24 | ZAP70 | 1.64531152 |
25 | TTN | 1.53828801 |
26 | GRK7 | 1.53589235 |
27 | JAK1 | 1.48358711 |
28 | IKBKB | 1.47202077 |
29 | TAOK1 | 1.46509757 |
30 | FGR | 1.41993722 |
31 | CDC42BPA | 1.41929884 |
32 | CSK | 1.36150562 |
33 | PAK4 | 1.35277236 |
34 | MAP2K3 | 1.33474438 |
35 | MET | 1.32842056 |
36 | CAMKK2 | 1.31722814 |
37 | HCK | 1.31618626 |
38 | PBK | 1.28837841 |
39 | SIK1 | 1.28512764 |
40 | CAMK1D | 1.27080236 |
41 | MAP3K3 | 1.25697133 |
42 | ITK | 1.19436624 |
43 | BMX | 1.17366939 |
44 | TXK | 1.16175974 |
45 | LMTK2 | 1.14905909 |
46 | IKBKE | 1.13854904 |
47 | MOS | 1.12906204 |
48 | MAPKAPK3 | 1.12568694 |
49 | LYN | 1.11440122 |
50 | BTK | 1.09755835 |
51 | LIMK1 | 1.09752126 |
52 | PDGFRA | 1.09540902 |
53 | BMPR2 | 1.05783964 |
54 | TESK2 | 1.03654639 |
55 | MAP3K1 | 1.02453601 |
56 | LRRK2 | 1.02188047 |
57 | CLK1 | 1.01928457 |
58 | PKN2 | 1.00280526 |
59 | ABL2 | 1.00055434 |
60 | BUB1 | 0.98542514 |
61 | JAK2 | 0.97152550 |
62 | JAK3 | 0.95445390 |
63 | LCK | 0.95010355 |
64 | SYK | 0.93417526 |
65 | TEC | 0.89935189 |
66 | MST1R | 0.89426191 |
67 | TRPM7 | 0.86222112 |
68 | KDR | 0.84177125 |
69 | SIK3 | 0.82085685 |
70 | PTK6 | 0.80891852 |
71 | ICK | 0.77642643 |
72 | PRKD2 | 0.76374199 |
73 | RPS6KA4 | 0.75137579 |
74 | SCYL2 | 0.72626815 |
75 | FES | 0.72163548 |
76 | ACVR1B | 0.71733585 |
77 | FGFR4 | 0.71411804 |
78 | PRKCD | 0.69798637 |
79 | PIM1 | 0.69677830 |
80 | PDK1 | 0.68966769 |
81 | MAP3K11 | 0.68822132 |
82 | PRKG2 | 0.66548046 |
83 | EGFR | 0.64642621 |
84 | MAP3K5 | 0.64173121 |
85 | ARAF | 0.63694300 |
86 | IRAK2 | 0.63039023 |
87 | MST4 | 0.63006571 |
88 | GRK5 | 0.62689072 |
89 | ILK | 0.61467842 |
90 | MAP2K2 | 0.60655595 |
91 | IRAK1 | 0.60194300 |
92 | CAMK1G | 0.59241150 |
93 | MARK3 | 0.58478891 |
94 | EPHB2 | 0.58300715 |
95 | MAP3K8 | 0.57987870 |
96 | MAPK11 | 0.57227879 |
97 | EIF2AK1 | 0.55754193 |
98 | MATK | 0.55598727 |
99 | RIPK1 | 0.54857928 |
100 | ADRBK2 | 0.54853184 |
101 | STK3 | 0.53999060 |
102 | DAPK3 | 0.53466246 |
103 | ABL1 | 0.53199734 |
104 | PDGFRB | 0.52710857 |
105 | EPHA2 | 0.52014755 |
106 | PIK3CG | 0.51257668 |
107 | HIPK2 | 0.48098044 |
108 | KSR2 | 0.47186874 |
109 | FER | 0.46237967 |
110 | CAMKK1 | 0.46024414 |
111 | CHUK | 0.45619197 |
112 | TNK2 | 0.43406199 |
113 | TSSK6 | 0.43363148 |
114 | MAP3K6 | 0.43218437 |
115 | MAPKAPK2 | 0.42417468 |
116 | EIF2AK2 | 0.42269512 |
117 | PDPK1 | 0.42002280 |
118 | MAP2K6 | 0.41739868 |
119 | PDK2 | 0.41522520 |
120 | IGF1R | 0.40857823 |
121 | PAK1 | 0.39966745 |
122 | PAK2 | 0.38948167 |
123 | STK4 | 0.37562267 |
124 | PTK2B | 0.36541525 |
125 | MAP3K13 | 0.35489978 |
126 | GSK3A | 0.35389258 |
127 | DYRK1B | 0.34716262 |
128 | BCKDK | 0.32947030 |
129 | PTK2 | 0.32581834 |
130 | MAPK15 | 0.31879753 |
131 | GRK6 | 0.31778222 |
132 | DDR2 | 0.30877091 |
133 | PRKD1 | 0.30511309 |
134 | CDK6 | 0.30145481 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Lysosome_Homo sapiens_hsa04142 | 4.38824162 |
2 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 4.31899663 |
3 | Other glycan degradation_Homo sapiens_hsa00511 | 4.20271618 |
4 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 4.15717205 |
5 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.47262145 |
6 | Leishmaniasis_Homo sapiens_hsa05140 | 2.26128318 |
7 | Malaria_Homo sapiens_hsa05144 | 2.03763437 |
8 | Phagosome_Homo sapiens_hsa04145 | 2.01051380 |
9 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.99539841 |
10 | Tuberculosis_Homo sapiens_hsa05152 | 1.90334699 |
11 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.89245744 |
12 | Pertussis_Homo sapiens_hsa05133 | 1.89173800 |
13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.88934820 |
14 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.84626892 |
15 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.83604778 |
16 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.79655190 |
17 | Legionellosis_Homo sapiens_hsa05134 | 1.61264787 |
18 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.53122050 |
19 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.52423176 |
20 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.51846544 |
21 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.47880180 |
22 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.47655586 |
23 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.44937976 |
24 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.44339413 |
25 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.25148518 |
26 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.21300146 |
27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20907824 |
28 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.17815183 |
29 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.16105460 |
30 | Apoptosis_Homo sapiens_hsa04210 | 1.14850237 |
31 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.13765757 |
32 | Measles_Homo sapiens_hsa05162 | 1.10058785 |
33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.08418383 |
34 | Salmonella infection_Homo sapiens_hsa05132 | 1.06918414 |
35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.06029908 |
36 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.04264521 |
37 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.03870894 |
38 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.03405893 |
39 | Prion diseases_Homo sapiens_hsa05020 | 1.01172764 |
40 | Bladder cancer_Homo sapiens_hsa05219 | 1.00688269 |
41 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.99010398 |
42 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.96242821 |
43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.96164992 |
44 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.95466878 |
45 | Mineral absorption_Homo sapiens_hsa04978 | 0.94166086 |
46 | Shigellosis_Homo sapiens_hsa05131 | 0.92814884 |
47 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.92196399 |
48 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90006004 |
49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.86950467 |
50 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.86939273 |
51 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.83118727 |
52 | Influenza A_Homo sapiens_hsa05164 | 0.82825722 |
53 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.81165796 |
54 | Galactose metabolism_Homo sapiens_hsa00052 | 0.80058430 |
55 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.80005319 |
56 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.78504959 |
57 | Allograft rejection_Homo sapiens_hsa05330 | 0.78395247 |
58 | Amoebiasis_Homo sapiens_hsa05146 | 0.77881221 |
59 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.77236880 |
60 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.76451110 |
61 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.76127532 |
62 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75998802 |
63 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.75512755 |
64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.72985128 |
65 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.67100451 |
66 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65983369 |
67 | Endocytosis_Homo sapiens_hsa04144 | 0.65842773 |
68 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.64179075 |
69 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.63971174 |
70 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.61895373 |
71 | Asthma_Homo sapiens_hsa05310 | 0.61764959 |
72 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.60214773 |
73 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59954122 |
74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59886013 |
75 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.58933865 |
76 | Focal adhesion_Homo sapiens_hsa04510 | 0.58799834 |
77 | Histidine metabolism_Homo sapiens_hsa00340 | 0.58161070 |
78 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.57875814 |
79 | Viral myocarditis_Homo sapiens_hsa05416 | 0.57748199 |
80 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.55826005 |
81 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55464728 |
82 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.52513275 |
83 | Hepatitis C_Homo sapiens_hsa05160 | 0.51830972 |
84 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.51070572 |
85 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50016265 |
86 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.49312062 |
87 | Hepatitis B_Homo sapiens_hsa05161 | 0.47970735 |
88 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.47820285 |
89 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.46905071 |
90 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.46755315 |
91 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.46103270 |
92 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45409486 |
93 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.44933101 |
94 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43719645 |
95 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.43311459 |
96 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43290117 |
97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.41295656 |
98 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.39384306 |
99 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.36410416 |
100 | Insulin resistance_Homo sapiens_hsa04931 | 0.36345949 |
101 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.35868886 |
102 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.35603796 |
103 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.35378646 |
104 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.35215305 |
105 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.34939756 |
106 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.34773498 |
107 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.34080963 |
108 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.33086031 |
109 | ABC transporters_Homo sapiens_hsa02010 | 0.33033828 |
110 | Proteasome_Homo sapiens_hsa03050 | 0.32971542 |
111 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.32619745 |
112 | Peroxisome_Homo sapiens_hsa04146 | 0.32226863 |
113 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.32064433 |
114 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.31691197 |
115 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.30734535 |
116 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.29442043 |
117 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.28768673 |
118 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.28701893 |
119 | Platelet activation_Homo sapiens_hsa04611 | 0.28395905 |
120 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27949555 |
121 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.24753540 |