Rank | Gene Set | Z-score |
---|---|---|
1 | neurofilament cytoskeleton organization (GO:0060052) | 6.63882275 |
2 | neuron cell-cell adhesion (GO:0007158) | 5.33842927 |
3 | dopamine transport (GO:0015872) | 5.19094695 |
4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.83671706 |
5 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.81131381 |
6 | synaptic vesicle exocytosis (GO:0016079) | 4.66848284 |
7 | vocalization behavior (GO:0071625) | 4.62127544 |
8 | dopamine biosynthetic process (GO:0042416) | 4.59141727 |
9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.49077839 |
10 | ATP synthesis coupled proton transport (GO:0015986) | 4.49077839 |
11 | catecholamine transport (GO:0051937) | 4.27551707 |
12 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.18982416 |
13 | synaptic transmission, dopaminergic (GO:0001963) | 4.16474077 |
14 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.07810698 |
15 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 4.07270791 |
16 | ATP hydrolysis coupled proton transport (GO:0015991) | 4.07270791 |
17 | respiratory electron transport chain (GO:0022904) | 3.97798919 |
18 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.97266551 |
19 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.96667724 |
20 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.94327071 |
21 | electron transport chain (GO:0022900) | 3.90584005 |
22 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.89158998 |
23 | response to histamine (GO:0034776) | 3.86887854 |
24 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.85494476 |
25 | neuron recognition (GO:0008038) | 3.84167534 |
26 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.83785367 |
27 | dendritic spine morphogenesis (GO:0060997) | 3.83206802 |
28 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.83160483 |
29 | regulation of glutamate secretion (GO:0014048) | 3.82099906 |
30 | gamma-aminobutyric acid transport (GO:0015812) | 3.80869504 |
31 | regulation of protein kinase A signaling (GO:0010738) | 3.80458588 |
32 | neuron-neuron synaptic transmission (GO:0007270) | 3.79707464 |
33 | positive regulation of synapse assembly (GO:0051965) | 3.76923754 |
34 | regulation of dopamine secretion (GO:0014059) | 3.75419053 |
35 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.75109973 |
36 | protein localization to synapse (GO:0035418) | 3.74958556 |
37 | C4-dicarboxylate transport (GO:0015740) | 3.68710975 |
38 | neurotransmitter secretion (GO:0007269) | 3.66528248 |
39 | auditory behavior (GO:0031223) | 3.66092267 |
40 | female mating behavior (GO:0060180) | 3.65742856 |
41 | neurotransmitter catabolic process (GO:0042135) | 3.64236744 |
42 | transferrin transport (GO:0033572) | 3.62830842 |
43 | serotonin metabolic process (GO:0042428) | 3.62157796 |
44 | presynaptic membrane assembly (GO:0097105) | 3.62121385 |
45 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.61715689 |
46 | regulation of dopamine metabolic process (GO:0042053) | 3.61510229 |
47 | regulation of catecholamine metabolic process (GO:0042069) | 3.61510229 |
48 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.59672049 |
49 | neuronal action potential (GO:0019228) | 3.56959252 |
50 | transmission of nerve impulse (GO:0019226) | 3.53845300 |
51 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.53004187 |
52 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.53004187 |
53 | potassium ion homeostasis (GO:0055075) | 3.49373339 |
54 | urinary tract smooth muscle contraction (GO:0014848) | 3.48796217 |
55 | opioid receptor signaling pathway (GO:0038003) | 3.48346802 |
56 | glutamate secretion (GO:0014047) | 3.48110432 |
57 | hindbrain development (GO:0030902) | 3.46946487 |
58 | behavioral response to cocaine (GO:0048148) | 3.45988216 |
59 | mating behavior (GO:0007617) | 3.44507296 |
60 | neurotransmitter transport (GO:0006836) | 3.44215517 |
61 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.42911119 |
62 | nucleobase catabolic process (GO:0046113) | 3.41471803 |
63 | glutamate receptor signaling pathway (GO:0007215) | 3.41110337 |
64 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.40833024 |
65 | negative regulation of neurotransmitter transport (GO:0051589) | 3.40779948 |
66 | behavioral response to nicotine (GO:0035095) | 3.40248752 |
67 | chaperone-mediated protein transport (GO:0072321) | 3.40199520 |
68 | neurotransmitter biosynthetic process (GO:0042136) | 3.40195459 |
69 | presynaptic membrane organization (GO:0097090) | 3.39697235 |
70 | ferric iron transport (GO:0015682) | 3.38356558 |
71 | trivalent inorganic cation transport (GO:0072512) | 3.38356558 |
72 | synaptic vesicle maturation (GO:0016188) | 3.36950774 |
73 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.36162806 |
74 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.34676842 |
75 | primary amino compound metabolic process (GO:1901160) | 3.33213971 |
76 | regulation of synaptic vesicle transport (GO:1902803) | 3.33181840 |
77 | regulation of neurotransmitter levels (GO:0001505) | 3.32479316 |
78 | catecholamine biosynthetic process (GO:0042423) | 3.31077511 |
79 | catechol-containing compound biosynthetic process (GO:0009713) | 3.31077511 |
80 | synaptic transmission, glutamatergic (GO:0035249) | 3.29471070 |
81 | regulation of female receptivity (GO:0045924) | 3.28450086 |
82 | response to cocaine (GO:0042220) | 3.28060116 |
83 | regulation of vesicle fusion (GO:0031338) | 3.27533053 |
84 | inner mitochondrial membrane organization (GO:0007007) | 3.25460974 |
85 | retina layer formation (GO:0010842) | 3.25013254 |
86 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.23129889 |
87 | striatum development (GO:0021756) | 3.22375868 |
88 | membrane depolarization during action potential (GO:0086010) | 3.22014187 |
89 | response to auditory stimulus (GO:0010996) | 3.19680325 |
90 | neuronal action potential propagation (GO:0019227) | 3.19448624 |
91 | regulation of synapse structural plasticity (GO:0051823) | 3.19276392 |
92 | neuromuscular process controlling posture (GO:0050884) | 3.17631746 |
93 | cell migration in hindbrain (GO:0021535) | 3.13081048 |
94 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.12899473 |
95 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.11089090 |
96 | prepulse inhibition (GO:0060134) | 3.09854859 |
97 | histone arginine methylation (GO:0034969) | 3.08066649 |
98 | regulation of respiratory system process (GO:0044065) | 3.06689602 |
99 | locomotory exploration behavior (GO:0035641) | 3.06004291 |
100 | exploration behavior (GO:0035640) | 3.06001526 |
101 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.05615846 |
102 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.04889724 |
103 | neurotransmitter uptake (GO:0001504) | 3.04356669 |
104 | startle response (GO:0001964) | 3.04198613 |
105 | positive regulation of neurotransmitter transport (GO:0051590) | 3.04004579 |
106 | proline transport (GO:0015824) | 3.03304256 |
107 | long-term synaptic potentiation (GO:0060291) | 3.03002748 |
108 | response to amphetamine (GO:0001975) | 3.01717311 |
109 | maternal behavior (GO:0042711) | 3.01470266 |
110 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.00440771 |
111 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.99571735 |
112 | response to insecticide (GO:0017085) | 2.99539215 |
113 | phenol-containing compound catabolic process (GO:0019336) | 2.99079229 |
114 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.97742861 |
115 | postsynaptic membrane organization (GO:0001941) | 2.97301668 |
116 | regulation of postsynaptic membrane potential (GO:0060078) | 2.96619229 |
117 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.96076225 |
118 | axonal fasciculation (GO:0007413) | 2.95846453 |
119 | protein localization to cilium (GO:0061512) | 2.95777654 |
120 | regulation of neurotransmitter uptake (GO:0051580) | 2.95570585 |
121 | positive regulation of amino acid transport (GO:0051957) | 2.94703281 |
122 | mechanosensory behavior (GO:0007638) | 2.94541201 |
123 | dendrite development (GO:0016358) | 2.93536919 |
124 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.93073026 |
125 | hydrogen ion transmembrane transport (GO:1902600) | 2.90553962 |
126 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.90155111 |
127 | membrane depolarization (GO:0051899) | 2.89488818 |
128 | phagosome maturation (GO:0090382) | 2.88967992 |
129 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.88111184 |
130 | detection of calcium ion (GO:0005513) | 2.84963303 |
131 | social behavior (GO:0035176) | 2.84015007 |
132 | intraspecies interaction between organisms (GO:0051703) | 2.84015007 |
133 | axonemal dynein complex assembly (GO:0070286) | 2.83291265 |
134 | behavioral fear response (GO:0001662) | 2.80933366 |
135 | behavioral defense response (GO:0002209) | 2.80933366 |
136 | positive regulation of action potential (GO:0045760) | 2.79897298 |
137 | adult walking behavior (GO:0007628) | 2.79551963 |
138 | negative regulation of membrane potential (GO:0045837) | 2.78480047 |
139 | positive regulation of vesicle fusion (GO:0031340) | 2.78337108 |
140 | positive regulation of amine transport (GO:0051954) | 2.76523680 |
141 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.73753000 |
142 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.73328032 |
143 | righting reflex (GO:0060013) | 2.73285454 |
144 | cerebellar granule cell differentiation (GO:0021707) | 2.73051007 |
145 | chemosensory behavior (GO:0007635) | 2.72693930 |
146 | neuron maturation (GO:0042551) | 2.70475906 |
147 | regulation of feeding behavior (GO:0060259) | 2.68475925 |
148 | action potential (GO:0001508) | 2.67566998 |
149 | neuromuscular synaptic transmission (GO:0007274) | 2.66455275 |
150 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.65470815 |
151 | detection of light stimulus involved in visual perception (GO:0050908) | 2.65470815 |
152 | regulation of respiratory gaseous exchange (GO:0043576) | 2.63671529 |
153 | regulation of synaptic transmission, GABAergic (GO:0032228) | 2.63033115 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.11171203 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.91586651 |
3 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.10292576 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.95588347 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.82977812 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.75147759 |
7 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.56314785 |
8 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.53456995 |
9 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.51500068 |
10 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.38744958 |
11 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.38224242 |
12 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.38077632 |
13 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.37675706 |
14 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.35163201 |
15 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.32624116 |
16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.28335530 |
17 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.23638694 |
18 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.18887514 |
19 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.17711752 |
20 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.17711752 |
21 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.17133255 |
22 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.16224861 |
23 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.13773970 |
24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.12983059 |
25 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.12176691 |
26 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.05453477 |
27 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.04662698 |
28 | VDR_22108803_ChIP-Seq_LS180_Human | 2.01694526 |
29 | P300_19829295_ChIP-Seq_ESCs_Human | 2.00941947 |
30 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.00474999 |
31 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.99827487 |
32 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.92078447 |
33 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.90190394 |
34 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.87909999 |
35 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.87719663 |
36 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.85897562 |
37 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.80443746 |
38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.77364000 |
39 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.67677388 |
40 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.66778117 |
41 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.66703442 |
42 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.66677779 |
43 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.66618132 |
44 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.66434599 |
45 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.63912941 |
46 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.61094822 |
47 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.58056731 |
48 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.54382078 |
49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.52765367 |
50 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.51842246 |
51 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.49735306 |
52 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.48498057 |
53 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.48496163 |
54 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.45832369 |
55 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.39652980 |
56 | AR_25329375_ChIP-Seq_VCAP_Human | 1.38555319 |
57 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.38363029 |
58 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.35059584 |
59 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.30996559 |
60 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.29952501 |
61 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.26956256 |
62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.23888136 |
63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.23888136 |
64 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.22597567 |
65 | JUN_21703547_ChIP-Seq_K562_Human | 1.21218155 |
66 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.19463393 |
67 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.19238823 |
68 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.18241198 |
69 | EWS_26573619_Chip-Seq_HEK293_Human | 1.16808931 |
70 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.14543224 |
71 | STAT3_23295773_ChIP-Seq_U87_Human | 1.13911386 |
72 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13844918 |
73 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.12097535 |
74 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.11603444 |
75 | TCF4_23295773_ChIP-Seq_U87_Human | 1.11186112 |
76 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.11033503 |
77 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.10518710 |
78 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.08302251 |
79 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.08195889 |
80 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.07929002 |
81 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07363945 |
82 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.06842924 |
83 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.06545867 |
84 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.06507087 |
85 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.06050336 |
86 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05635900 |
87 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04210493 |
88 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.02937260 |
89 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.02431491 |
90 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.02232588 |
91 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.00892223 |
92 | AR_19668381_ChIP-Seq_PC3_Human | 0.96343928 |
93 | KDM2B_26808549_Chip-Seq_REH_Human | 0.96179783 |
94 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.95407133 |
95 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.95156786 |
96 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.95030818 |
97 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94448699 |
98 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94433943 |
99 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.94027356 |
100 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93492334 |
101 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.93492334 |
102 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.93133308 |
103 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.92443285 |
104 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.92315688 |
105 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.92111279 |
106 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.91991535 |
107 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.91604435 |
108 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.90955926 |
109 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.90950018 |
110 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.90817750 |
111 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.90215081 |
112 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.89908345 |
113 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.89418157 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.26904242 |
2 | MP0001529_abnormal_vocalization | 3.93617067 |
3 | MP0004859_abnormal_synaptic_plasticity | 3.71062786 |
4 | MP0002102_abnormal_ear_morphology | 3.38305030 |
5 | MP0003635_abnormal_synaptic_transmissio | 3.37192715 |
6 | MP0006276_abnormal_autonomic_nervous | 3.37172642 |
7 | MP0009745_abnormal_behavioral_response | 3.17595081 |
8 | MP0009046_muscle_twitch | 3.00894172 |
9 | MP0002064_seizures | 2.97115999 |
10 | MP0001968_abnormal_touch/_nociception | 2.90073463 |
11 | MP0002822_catalepsy | 2.90043540 |
12 | MP0001440_abnormal_grooming_behavior | 2.84643758 |
13 | MP0003122_maternal_imprinting | 2.78455704 |
14 | MP0001501_abnormal_sleep_pattern | 2.77115528 |
15 | MP0002063_abnormal_learning/memory/cond | 2.75473038 |
16 | MP0002572_abnormal_emotion/affect_behav | 2.73199608 |
17 | MP0001905_abnormal_dopamine_level | 2.69860249 |
18 | MP0002736_abnormal_nociception_after | 2.63355707 |
19 | MP0004270_analgesia | 2.56061551 |
20 | MP0002272_abnormal_nervous_system | 2.54130606 |
21 | MP0002735_abnormal_chemical_nociception | 2.52042442 |
22 | MP0002734_abnormal_mechanical_nocicepti | 2.47239005 |
23 | MP0005645_abnormal_hypothalamus_physiol | 2.46251460 |
24 | MP0002837_dystrophic_cardiac_calcinosis | 2.34444325 |
25 | MP0005423_abnormal_somatic_nervous | 2.27108398 |
26 | MP0001986_abnormal_taste_sensitivity | 2.20095070 |
27 | MP0005386_behavior/neurological_phenoty | 2.13319972 |
28 | MP0004924_abnormal_behavior | 2.13319972 |
29 | MP0002733_abnormal_thermal_nociception | 2.11909800 |
30 | MP0001486_abnormal_startle_reflex | 2.10400511 |
31 | MP0001970_abnormal_pain_threshold | 2.05404667 |
32 | MP0002067_abnormal_sensory_capabilities | 1.94925176 |
33 | MP0004142_abnormal_muscle_tone | 1.83704709 |
34 | MP0002184_abnormal_innervation | 1.75880165 |
35 | MP0002557_abnormal_social/conspecific_i | 1.74236587 |
36 | MP0001984_abnormal_olfaction | 1.65435672 |
37 | MP0000778_abnormal_nervous_system | 1.61300362 |
38 | MP0002876_abnormal_thyroid_physiology | 1.60236128 |
39 | MP0003195_calcinosis | 1.57144838 |
40 | MP0010386_abnormal_urinary_bladder | 1.52552478 |
41 | MP0001188_hyperpigmentation | 1.47819814 |
42 | MP0005646_abnormal_pituitary_gland | 1.46648056 |
43 | MP0003787_abnormal_imprinting | 1.40461598 |
44 | MP0001502_abnormal_circadian_rhythm | 1.39418992 |
45 | MP0002909_abnormal_adrenal_gland | 1.38529552 |
46 | MP0005187_abnormal_penis_morphology | 1.35326007 |
47 | MP0003329_amyloid_beta_deposits | 1.34766668 |
48 | MP0008872_abnormal_physiological_respon | 1.32657688 |
49 | MP0000013_abnormal_adipose_tissue | 1.32656355 |
50 | MP0003879_abnormal_hair_cell | 1.31838046 |
51 | MP0002066_abnormal_motor_capabilities/c | 1.29295518 |
52 | MP0005379_endocrine/exocrine_gland_phen | 1.25099878 |
53 | MP0003011_delayed_dark_adaptation | 1.22094295 |
54 | MP0002882_abnormal_neuron_morphology | 1.19013615 |
55 | MP0000955_abnormal_spinal_cord | 1.18410072 |
56 | MP0004043_abnormal_pH_regulation | 1.16601705 |
57 | MP0008569_lethality_at_weaning | 1.15300984 |
58 | MP0000751_myopathy | 1.13290217 |
59 | MP0004510_myositis | 1.13081533 |
60 | MP0004811_abnormal_neuron_physiology | 1.12668509 |
61 | MP0004133_heterotaxia | 1.10669514 |
62 | MP0005535_abnormal_body_temperature | 1.07159439 |
63 | MP0003121_genomic_imprinting | 1.06906901 |
64 | MP0003283_abnormal_digestive_organ | 1.05987233 |
65 | MP0005551_abnormal_eye_electrophysiolog | 1.05350165 |
66 | MP0002069_abnormal_eating/drinking_beha | 1.04018917 |
67 | MP0001664_abnormal_digestion | 1.01763030 |
68 | MP0008875_abnormal_xenobiotic_pharmacok | 1.01756521 |
69 | MP0000569_abnormal_digit_pigmentation | 0.97198683 |
70 | MP0006072_abnormal_retinal_apoptosis | 0.96632794 |
71 | MP0009780_abnormal_chondrocyte_physiolo | 0.96455779 |
72 | MP0002693_abnormal_pancreas_physiology | 0.95366686 |
73 | MP0000372_irregular_coat_pigmentation | 0.95246755 |
74 | MP0002163_abnormal_gland_morphology | 0.94945968 |
75 | MP0006035_abnormal_mitochondrial_morpho | 0.93968741 |
76 | MP0000427_abnormal_hair_cycle | 0.93588607 |
77 | MP0004742_abnormal_vestibular_system | 0.92212675 |
78 | MP0003633_abnormal_nervous_system | 0.91604283 |
79 | MP0002638_abnormal_pupillary_reflex | 0.90298717 |
80 | MP0002160_abnormal_reproductive_system | 0.89880957 |
81 | MP0002229_neurodegeneration | 0.89132283 |
82 | MP0005389_reproductive_system_phenotype | 0.88375314 |
83 | MP0005253_abnormal_eye_physiology | 0.87928781 |
84 | MP0002938_white_spotting | 0.87506146 |
85 | MP0004145_abnormal_muscle_electrophysio | 0.87477440 |
86 | MP0002152_abnormal_brain_morphology | 0.86953427 |
87 | MP0000631_abnormal_neuroendocrine_gland | 0.86325388 |
88 | MP0003631_nervous_system_phenotype | 0.84674354 |
89 | MP0003123_paternal_imprinting | 0.84418225 |
90 | MP0004147_increased_porphyrin_level | 0.84119022 |
91 | MP0005248_abnormal_Harderian_gland | 0.83741472 |
92 | MP0005409_darkened_coat_color | 0.83280362 |
93 | MP0001485_abnormal_pinna_reflex | 0.82317359 |
94 | MP0003315_abnormal_perineum_morphology | 0.81992078 |
95 | MP0002332_abnormal_exercise_endurance | 0.80692945 |
96 | MP0000538_abnormal_urinary_bladder | 0.79039715 |
97 | MP0009379_abnormal_foot_pigmentation | 0.78725003 |
98 | MP0002090_abnormal_vision | 0.78334180 |
99 | MP0003183_abnormal_peptide_metabolism | 0.78188800 |
100 | MP0003868_abnormal_feces_composition | 0.78115934 |
101 | MP0005499_abnormal_olfactory_system | 0.77438385 |
102 | MP0005394_taste/olfaction_phenotype | 0.77438385 |
103 | MP0001944_abnormal_pancreas_morphology | 0.76101821 |
104 | MP0001963_abnormal_hearing_physiology | 0.76074463 |
105 | MP0002752_abnormal_somatic_nervous | 0.75888013 |
106 | MP0004085_abnormal_heartbeat | 0.75303216 |
107 | MP0008874_decreased_physiological_sensi | 0.74558243 |
108 | MP0001299_abnormal_eye_distance/ | 0.73462648 |
109 | MP0002751_abnormal_autonomic_nervous | 0.73147904 |
110 | MP0004858_abnormal_nervous_system | 0.72218204 |
111 | MP0003634_abnormal_glial_cell | 0.66435850 |
112 | MP0001943_abnormal_respiration | 0.63977801 |
113 | MP0006036_abnormal_mitochondrial_physio | 0.63792227 |
114 | MP0003632_abnormal_nervous_system | 0.61003118 |
115 | MP0008877_abnormal_DNA_methylation | 0.59238692 |
116 | MP0005410_abnormal_fertilization | 0.58653096 |
117 | MP0003959_abnormal_lean_body | 0.54718702 |
118 | MP0005171_absent_coat_pigmentation | 0.54509497 |
119 | MP0003690_abnormal_glial_cell | 0.54507418 |
120 | MP0004215_abnormal_myocardial_fiber | 0.54036081 |
121 | MP0004885_abnormal_endolymph | 0.52958387 |
122 | MP0000604_amyloidosis | 0.51851559 |
123 | MP0000639_abnormal_adrenal_gland | 0.51481213 |
124 | MP0004036_abnormal_muscle_relaxation | 0.50867020 |
125 | MP0000747_muscle_weakness | 0.49931253 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 6.27972132 |
2 | Limb dystonia (HP:0002451) | 5.55664979 |
3 | Visual hallucinations (HP:0002367) | 4.80390424 |
4 | Acute necrotizing encephalopathy (HP:0006965) | 4.79527386 |
5 | Atonic seizures (HP:0010819) | 4.71685460 |
6 | Myokymia (HP:0002411) | 4.61895534 |
7 | Focal seizures (HP:0007359) | 4.59913005 |
8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.46444808 |
9 | Progressive macrocephaly (HP:0004481) | 4.21212060 |
10 | Mitochondrial inheritance (HP:0001427) | 4.01657393 |
11 | Pheochromocytoma (HP:0002666) | 4.00162765 |
12 | Absence seizures (HP:0002121) | 3.92370242 |
13 | Hypothermia (HP:0002045) | 3.92346186 |
14 | Febrile seizures (HP:0002373) | 3.83937002 |
15 | Neuroendocrine neoplasm (HP:0100634) | 3.80670702 |
16 | Acute encephalopathy (HP:0006846) | 3.64731274 |
17 | Epileptic encephalopathy (HP:0200134) | 3.56999535 |
18 | Dialeptic seizures (HP:0011146) | 3.56616536 |
19 | Progressive cerebellar ataxia (HP:0002073) | 3.51467579 |
20 | Generalized tonic-clonic seizures (HP:0002069) | 3.48535477 |
21 | Action tremor (HP:0002345) | 3.34989520 |
22 | Polyphagia (HP:0002591) | 3.33777912 |
23 | Hyperventilation (HP:0002883) | 3.31222496 |
24 | Increased CSF lactate (HP:0002490) | 3.27058687 |
25 | Gait imbalance (HP:0002141) | 3.24312290 |
26 | Failure to thrive in infancy (HP:0001531) | 3.17419892 |
27 | Hepatocellular necrosis (HP:0001404) | 3.08040388 |
28 | Abnormal hair whorl (HP:0010721) | 3.07923758 |
29 | Medial flaring of the eyebrow (HP:0010747) | 2.97597694 |
30 | Congenital primary aphakia (HP:0007707) | 2.96264765 |
31 | Ulnar claw (HP:0001178) | 2.95922391 |
32 | Chronic otitis media (HP:0000389) | 2.91163618 |
33 | Protruding tongue (HP:0010808) | 2.87386275 |
34 | Abnormal pupillary function (HP:0007686) | 2.86766392 |
35 | Anxiety (HP:0000739) | 2.82611930 |
36 | Cerebral inclusion bodies (HP:0100314) | 2.81633162 |
37 | Hypoglycemic coma (HP:0001325) | 2.80435979 |
38 | Abnormal eating behavior (HP:0100738) | 2.77486749 |
39 | Hemiparesis (HP:0001269) | 2.77076635 |
40 | Optic disc pallor (HP:0000543) | 2.74195518 |
41 | Nephrogenic diabetes insipidus (HP:0009806) | 2.73973876 |
42 | Ketoacidosis (HP:0001993) | 2.73368461 |
43 | Poor suck (HP:0002033) | 2.69765803 |
44 | Hypoventilation (HP:0002791) | 2.67963006 |
45 | Broad-based gait (HP:0002136) | 2.60978241 |
46 | Abnormal ciliary motility (HP:0012262) | 2.56426540 |
47 | Increased hepatocellular lipid droplets (HP:0006565) | 2.56345714 |
48 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.55596150 |
49 | Enlarged penis (HP:0000040) | 2.55417884 |
50 | Genital tract atresia (HP:0001827) | 2.53829756 |
51 | Oligodactyly (hands) (HP:0001180) | 2.52744003 |
52 | Vaginal atresia (HP:0000148) | 2.52512450 |
53 | Pancreatic cysts (HP:0001737) | 2.52204013 |
54 | Truncal ataxia (HP:0002078) | 2.47244342 |
55 | Amblyopia (HP:0000646) | 2.46279665 |
56 | Oligomenorrhea (HP:0000876) | 2.45109387 |
57 | Leukodystrophy (HP:0002415) | 2.44840726 |
58 | Progressive inability to walk (HP:0002505) | 2.41208229 |
59 | Cerebral edema (HP:0002181) | 2.40714443 |
60 | Postural instability (HP:0002172) | 2.37946652 |
61 | Hypoglycemic seizures (HP:0002173) | 2.37348244 |
62 | Delusions (HP:0000746) | 2.35340733 |
63 | Esotropia (HP:0000565) | 2.33275566 |
64 | Akinesia (HP:0002304) | 2.29577072 |
65 | Absent/shortened dynein arms (HP:0200106) | 2.26874299 |
66 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.26874299 |
67 | Delayed gross motor development (HP:0002194) | 2.26532793 |
68 | Ventricular fibrillation (HP:0001663) | 2.25863814 |
69 | Abnormality of salivation (HP:0100755) | 2.25722646 |
70 | Renal Fanconi syndrome (HP:0001994) | 2.23954255 |
71 | Cerebral hemorrhage (HP:0001342) | 2.23206548 |
72 | Neurofibrillary tangles (HP:0002185) | 2.22884486 |
73 | Pancreatic fibrosis (HP:0100732) | 2.22850559 |
74 | Lipid accumulation in hepatocytes (HP:0006561) | 2.20276249 |
75 | Chronic sinusitis (HP:0011109) | 2.18228320 |
76 | Excessive salivation (HP:0003781) | 2.17964567 |
77 | Drooling (HP:0002307) | 2.17964567 |
78 | Agitation (HP:0000713) | 2.17861229 |
79 | Septo-optic dysplasia (HP:0100842) | 2.17061601 |
80 | Epileptiform EEG discharges (HP:0011182) | 2.16484470 |
81 | Psychosis (HP:0000709) | 2.14884423 |
82 | Respiratory failure (HP:0002878) | 2.12760338 |
83 | Exercise intolerance (HP:0003546) | 2.12709297 |
84 | Sensory axonal neuropathy (HP:0003390) | 2.11930570 |
85 | Gaze-evoked nystagmus (HP:0000640) | 2.11884595 |
86 | Supranuclear gaze palsy (HP:0000605) | 2.11741908 |
87 | Mutism (HP:0002300) | 2.11721833 |
88 | Inability to walk (HP:0002540) | 2.11510150 |
89 | Specific learning disability (HP:0001328) | 2.09547915 |
90 | Hypomagnesemia (HP:0002917) | 2.08232151 |
91 | Hepatic necrosis (HP:0002605) | 2.07953368 |
92 | Status epilepticus (HP:0002133) | 2.07407415 |
93 | Urinary urgency (HP:0000012) | 2.06985342 |
94 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.06638055 |
95 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.06638055 |
96 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.03623115 |
97 | EEG with generalized epileptiform discharges (HP:0011198) | 2.03402840 |
98 | True hermaphroditism (HP:0010459) | 2.02993776 |
99 | Postural tremor (HP:0002174) | 2.02992623 |
100 | Poor coordination (HP:0002370) | 2.02750693 |
101 | Depression (HP:0000716) | 2.02204517 |
102 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.01349081 |
103 | Abnormality of the labia minora (HP:0012880) | 2.00534608 |
104 | Diminished movement (HP:0002374) | 1.97746223 |
105 | Narrow nasal bridge (HP:0000446) | 1.97264278 |
106 | Lactic acidosis (HP:0003128) | 1.97108203 |
107 | Muscular hypotonia of the trunk (HP:0008936) | 1.96430712 |
108 | Hypokinesia (HP:0002375) | 1.96263898 |
109 | Dysmetria (HP:0001310) | 1.95708157 |
110 | X-linked dominant inheritance (HP:0001423) | 1.95034677 |
111 | Papilledema (HP:0001085) | 1.94616197 |
112 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.94371947 |
113 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.94142247 |
114 | Increased intramyocellular lipid droplets (HP:0012240) | 1.93646996 |
115 | Dysdiadochokinesis (HP:0002075) | 1.93023402 |
116 | Spastic tetraplegia (HP:0002510) | 1.92752249 |
117 | Blue irides (HP:0000635) | 1.92323437 |
118 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92199818 |
119 | Mixed hearing impairment (HP:0000410) | 1.90086430 |
120 | Hyperthyroidism (HP:0000836) | 1.89186200 |
121 | Emotional lability (HP:0000712) | 1.88749929 |
122 | Large for gestational age (HP:0001520) | 1.88409935 |
123 | Dyskinesia (HP:0100660) | 1.87457949 |
124 | Orthostatic hypotension (HP:0001278) | 1.87075139 |
125 | Fetal akinesia sequence (HP:0001989) | 1.86974102 |
126 | Supernumerary nipples (HP:0002558) | 1.86549920 |
127 | Hypsarrhythmia (HP:0002521) | 1.86077334 |
128 | Spastic gait (HP:0002064) | 1.85009834 |
129 | Pendular nystagmus (HP:0012043) | 1.84900665 |
130 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.84709089 |
131 | Ketosis (HP:0001946) | 1.83479979 |
132 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.83174547 |
133 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.83174547 |
134 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.82870961 |
135 | Diplopia (HP:0000651) | 1.82470207 |
136 | Abnormality of binocular vision (HP:0011514) | 1.82470207 |
137 | Tachypnea (HP:0002789) | 1.82469249 |
138 | Abnormality of the corticospinal tract (HP:0002492) | 1.82415563 |
139 | Ankle clonus (HP:0011448) | 1.82133368 |
140 | Intention tremor (HP:0002080) | 1.76241608 |
141 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.74983193 |
142 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.74983193 |
143 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.74007005 |
144 | Congenital stationary night blindness (HP:0007642) | 1.72751638 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K12 | 4.96882469 |
2 | PINK1 | 3.59891874 |
3 | CASK | 3.57874094 |
4 | FRK | 3.53403384 |
5 | NTRK3 | 3.39283483 |
6 | MAP3K4 | 3.28575821 |
7 | MAP2K7 | 2.86103839 |
8 | PNCK | 2.78224102 |
9 | MAP2K4 | 2.38515142 |
10 | MARK1 | 2.30385611 |
11 | PLK2 | 2.25033425 |
12 | ARAF | 2.23218780 |
13 | GRK5 | 2.19243233 |
14 | MINK1 | 2.16572837 |
15 | GRK7 | 2.08442287 |
16 | TLK1 | 2.06440908 |
17 | EPHA4 | 1.98627427 |
18 | MAP3K9 | 1.88998496 |
19 | NME1 | 1.88485459 |
20 | INSRR | 1.87616259 |
21 | WNK3 | 1.85433566 |
22 | NTRK2 | 1.77557044 |
23 | CDK19 | 1.73924485 |
24 | ADRBK2 | 1.64825380 |
25 | TNIK | 1.59017884 |
26 | MAPKAPK5 | 1.56695704 |
27 | OXSR1 | 1.51701339 |
28 | SIK3 | 1.51210202 |
29 | MAPK13 | 1.46798462 |
30 | DYRK2 | 1.42039679 |
31 | EPHA3 | 1.41877737 |
32 | MAP4K2 | 1.40474356 |
33 | NTRK1 | 1.39810911 |
34 | UHMK1 | 1.37341256 |
35 | TSSK6 | 1.36188890 |
36 | CAMK2A | 1.34790066 |
37 | MAPK15 | 1.33463019 |
38 | DAPK1 | 1.30253110 |
39 | FGR | 1.24790334 |
40 | ZAK | 1.21929954 |
41 | CAMK2B | 1.21907308 |
42 | BCR | 1.18831838 |
43 | AKT3 | 1.18138935 |
44 | CDK5 | 1.16962114 |
45 | DAPK2 | 1.14308177 |
46 | PRKCG | 1.14121728 |
47 | SIK2 | 1.09847907 |
48 | STK39 | 1.09016627 |
49 | GRK6 | 1.07983668 |
50 | WNK4 | 1.02960290 |
51 | CAMKK2 | 1.02724854 |
52 | PTK2B | 1.02382517 |
53 | FES | 1.02012584 |
54 | ADRBK1 | 1.00981127 |
55 | PASK | 1.00808782 |
56 | RIPK4 | 0.99681152 |
57 | CAMK2D | 0.96608860 |
58 | PRPF4B | 0.94184381 |
59 | CSNK1G2 | 0.93016594 |
60 | FGFR2 | 0.91764982 |
61 | BRAF | 0.91444226 |
62 | MYLK | 0.90606497 |
63 | DYRK1A | 0.86996858 |
64 | KSR1 | 0.86563608 |
65 | CSNK1G3 | 0.86117006 |
66 | KSR2 | 0.85595142 |
67 | CDK14 | 0.85291429 |
68 | TNK2 | 0.83062103 |
69 | PAK3 | 0.81922102 |
70 | BMPR2 | 0.80882118 |
71 | CDK18 | 0.80529244 |
72 | PAK6 | 0.78044549 |
73 | PRKCZ | 0.75314938 |
74 | CDK15 | 0.74258656 |
75 | CAMK2G | 0.74046718 |
76 | PRKCE | 0.73576329 |
77 | ERBB3 | 0.73256209 |
78 | TAOK1 | 0.67788814 |
79 | IRAK2 | 0.65797926 |
80 | MUSK | 0.65563301 |
81 | CDK11A | 0.63937727 |
82 | SGK223 | 0.63388476 |
83 | SGK494 | 0.63388476 |
84 | PHKG1 | 0.63255407 |
85 | PHKG2 | 0.63255407 |
86 | CDK3 | 0.62470125 |
87 | RPS6KA5 | 0.60942530 |
88 | CSNK1A1 | 0.57343906 |
89 | GRK1 | 0.56580654 |
90 | LIMK1 | 0.55190512 |
91 | CAMKK1 | 0.55067539 |
92 | STK16 | 0.54050715 |
93 | LATS2 | 0.53400109 |
94 | CAMK4 | 0.51829640 |
95 | SGK3 | 0.51376848 |
96 | ROCK2 | 0.51247981 |
97 | PRKACA | 0.49736451 |
98 | FER | 0.49646504 |
99 | MAP3K6 | 0.46700019 |
100 | MAP3K11 | 0.45294005 |
101 | CAMK1 | 0.44776273 |
102 | RAF1 | 0.44296710 |
103 | MARK3 | 0.44252433 |
104 | SGK1 | 0.43278981 |
105 | CSNK1G1 | 0.42830371 |
106 | MARK2 | 0.42586724 |
107 | PKN1 | 0.41783120 |
108 | YES1 | 0.41062849 |
109 | MAP3K13 | 0.40327692 |
110 | EPHB1 | 0.39839332 |
111 | PRKACB | 0.39209620 |
112 | SGK2 | 0.39059920 |
113 | MAPK12 | 0.37807005 |
114 | RPS6KA3 | 0.37266519 |
115 | BMPR1B | 0.37220177 |
116 | PDK1 | 0.36323531 |
117 | MAP2K1 | 0.34051211 |
118 | PRKAA1 | 0.33529512 |
119 | PRKCB | 0.32958542 |
120 | MST4 | 0.32127768 |
121 | STK11 | 0.31698425 |
122 | PRKCH | 0.31395643 |
123 | PRKCA | 0.31179848 |
124 | PRKG1 | 0.31077265 |
125 | CAMK1G | 0.30808062 |
126 | IRAK1 | 0.30658147 |
127 | PLK3 | 0.30279998 |
128 | RET | 0.29444901 |
129 | PRKCQ | 0.29289459 |
130 | DAPK3 | 0.29143845 |
131 | MAP3K1 | 0.27219267 |
132 | CSNK1E | 0.27105432 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.26496523 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.94106806 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.48647327 |
4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.43338792 |
5 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 3.41963165 |
6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.97754159 |
7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.78425873 |
8 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.56479939 |
9 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.52499057 |
10 | GABAergic synapse_Homo sapiens_hsa04727 | 2.48090250 |
11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.30733866 |
12 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.26274773 |
13 | Cocaine addiction_Homo sapiens_hsa05030 | 2.12262622 |
14 | Olfactory transduction_Homo sapiens_hsa04740 | 2.08483686 |
15 | Morphine addiction_Homo sapiens_hsa05032 | 2.06239873 |
16 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.05798481 |
17 | Serotonergic synapse_Homo sapiens_hsa04726 | 2.01102585 |
18 | Circadian entrainment_Homo sapiens_hsa04713 | 2.00819849 |
19 | Long-term potentiation_Homo sapiens_hsa04720 | 1.97347078 |
20 | Taste transduction_Homo sapiens_hsa04742 | 1.92191712 |
21 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.87508755 |
22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.84800736 |
23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.74950931 |
24 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.63090041 |
25 | Long-term depression_Homo sapiens_hsa04730 | 1.61328812 |
26 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.59865190 |
27 | Insulin secretion_Homo sapiens_hsa04911 | 1.54938656 |
28 | Renin secretion_Homo sapiens_hsa04924 | 1.54631710 |
29 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.52358430 |
30 | Salivary secretion_Homo sapiens_hsa04970 | 1.50793773 |
31 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.45106250 |
32 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.39271561 |
33 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.34398748 |
34 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.26378616 |
35 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.19201188 |
36 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.15159868 |
37 | Phototransduction_Homo sapiens_hsa04744 | 1.12928881 |
38 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.12431215 |
39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.11760791 |
40 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.09471226 |
41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.08818609 |
42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.06364567 |
43 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.01080750 |
44 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.98624778 |
45 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.98193905 |
46 | Gap junction_Homo sapiens_hsa04540 | 0.95886328 |
47 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.95210474 |
48 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.93846026 |
49 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.93082130 |
50 | Protein export_Homo sapiens_hsa03060 | 0.85508426 |
51 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.80373368 |
52 | Proteasome_Homo sapiens_hsa03050 | 0.80358425 |
53 | Phagosome_Homo sapiens_hsa04145 | 0.80333066 |
54 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.80019330 |
55 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.77932108 |
56 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.75611446 |
57 | Circadian rhythm_Homo sapiens_hsa04710 | 0.73831100 |
58 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.71993360 |
59 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.70779541 |
60 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.70570635 |
61 | Axon guidance_Homo sapiens_hsa04360 | 0.69001121 |
62 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.68406511 |
63 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.67292051 |
64 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66831572 |
65 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.62237881 |
66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61176109 |
67 | Melanogenesis_Homo sapiens_hsa04916 | 0.60525469 |
68 | Alcoholism_Homo sapiens_hsa05034 | 0.59570598 |
69 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.59114069 |
70 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58680391 |
71 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.57092327 |
72 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.54903523 |
73 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.54201936 |
74 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.53994106 |
75 | Mineral absorption_Homo sapiens_hsa04978 | 0.53605042 |
76 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.53027274 |
77 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.51913045 |
78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.50073617 |
79 | Prion diseases_Homo sapiens_hsa05020 | 0.49593764 |
80 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.49545718 |
81 | Peroxisome_Homo sapiens_hsa04146 | 0.49403762 |
82 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.49143156 |
83 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.47718953 |
84 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.47442397 |
85 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.47289617 |
86 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.46525084 |
87 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.45709699 |
88 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.44019605 |
89 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.43121896 |
90 | Sulfur relay system_Homo sapiens_hsa04122 | 0.42900518 |
91 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42019702 |
92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41789069 |
93 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.41618705 |
94 | ABC transporters_Homo sapiens_hsa02010 | 0.41597887 |
95 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.37148699 |
96 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.36621673 |
97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.35818334 |
98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34086881 |
99 | Histidine metabolism_Homo sapiens_hsa00340 | 0.32325203 |
100 | Bile secretion_Homo sapiens_hsa04976 | 0.31444446 |
101 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.30901222 |
102 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.30631781 |
103 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.28857674 |
104 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.28140836 |
105 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.27644758 |
106 | Basal transcription factors_Homo sapiens_hsa03022 | 0.27037239 |
107 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.26416661 |
108 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.25667777 |
109 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.25404709 |
110 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.24995304 |
111 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.24920023 |
112 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.24660007 |
113 | Metabolic pathways_Homo sapiens_hsa01100 | 0.22755812 |
114 | Glioma_Homo sapiens_hsa05214 | 0.22096049 |
115 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.21943602 |
116 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.21075442 |
117 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.20123828 |
118 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.20040895 |
119 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.19241805 |
120 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.16260727 |
121 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.16079531 |
122 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.15934544 |
123 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.13001600 |
124 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.12378661 |
125 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.11206112 |