CUEDC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.31428087
2sequestering of actin monomers (GO:0042989)4.80949099
3DNA deamination (GO:0045006)4.74724927
4viral transcription (GO:0019083)4.47460408
5establishment of protein localization to mitochondrial membrane (GO:0090151)4.25772952
6translational termination (GO:0006415)4.25725282
7chaperone-mediated protein transport (GO:0072321)4.14219123
8neuronal action potential propagation (GO:0019227)3.97947908
9mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.86878607
10translational elongation (GO:0006414)3.86149456
11cullin deneddylation (GO:0010388)3.81731492
12protein deneddylation (GO:0000338)3.76295312
13telomere maintenance via semi-conservative replication (GO:0032201)3.73136214
14protein complex biogenesis (GO:0070271)3.70778014
15SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.68503381
16cellular protein complex disassembly (GO:0043624)3.64970933
17cotranslational protein targeting to membrane (GO:0006613)3.63026646
18ribosomal small subunit biogenesis (GO:0042274)3.61187347
19energy coupled proton transport, down electrochemical gradient (GO:0015985)3.59705223
20ATP synthesis coupled proton transport (GO:0015986)3.59705223
21DNA strand elongation involved in DNA replication (GO:0006271)3.59183700
22regulation of mitochondrial translation (GO:0070129)3.58956160
23protein targeting to ER (GO:0045047)3.58808047
24pyrimidine nucleobase catabolic process (GO:0006208)3.54673254
25establishment of mitochondrion localization (GO:0051654)3.51522973
26mitochondrial respiratory chain complex assembly (GO:0033108)3.48959086
27viral life cycle (GO:0019058)3.43487708
28DNA strand elongation (GO:0022616)3.42966864
29negative regulation of microtubule polymerization (GO:0031115)3.42416587
30maturation of SSU-rRNA (GO:0030490)3.42331203
31formation of translation preinitiation complex (GO:0001731)3.42051172
32deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.41950480
33regulation of oxidative phosphorylation (GO:0002082)3.40461934
34protein localization to endoplasmic reticulum (GO:0070972)3.39049545
35peptidyl-arginine omega-N-methylation (GO:0035247)3.39006828
36establishment of protein localization to endoplasmic reticulum (GO:0072599)3.38738589
37RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.36688208
38tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.36688208
39oxidative phosphorylation (GO:0006119)3.36556241
40translational initiation (GO:0006413)3.35632794
41nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.29355694
42ATP biosynthetic process (GO:0006754)3.28486457
43protein complex disassembly (GO:0043241)3.27384834
44purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.26473790
45purine nucleoside triphosphate biosynthetic process (GO:0009145)3.25646242
46establishment of integrated proviral latency (GO:0075713)3.22629202
47macromolecular complex disassembly (GO:0032984)3.20444054
48GTP biosynthetic process (GO:0006183)3.20100345
49synaptic vesicle exocytosis (GO:0016079)3.18317656
50cytochrome complex assembly (GO:0017004)3.13519482
51postsynaptic membrane organization (GO:0001941)3.12116973
52guanosine-containing compound biosynthetic process (GO:1901070)3.09027241
53ribonucleoside triphosphate biosynthetic process (GO:0009201)3.08064230
54mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.05124019
55ribosomal large subunit biogenesis (GO:0042273)3.02727181
56spliceosomal snRNP assembly (GO:0000387)3.01645374
57DNA damage response, detection of DNA damage (GO:0042769)3.01244479
58respiratory electron transport chain (GO:0022904)3.00863286
59telomere maintenance via recombination (GO:0000722)3.00212817
60CTP metabolic process (GO:0046036)2.98517921
61CTP biosynthetic process (GO:0006241)2.98517921
62ubiquinone biosynthetic process (GO:0006744)2.98224833
63respiratory chain complex IV assembly (GO:0008535)2.97578699
64protein maturation by protein folding (GO:0022417)2.97057599
65protein targeting to mitochondrion (GO:0006626)2.94823157
66deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.94707994
67electron transport chain (GO:0022900)2.94685280
68translation (GO:0006412)2.94666237
69negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.94411568
70hydrogen ion transmembrane transport (GO:1902600)2.93919471
71pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.93611218
72aldehyde catabolic process (GO:0046185)2.93033579
73pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.92855689
74histone arginine methylation (GO:0034969)2.92559636
75metallo-sulfur cluster assembly (GO:0031163)2.90874690
76iron-sulfur cluster assembly (GO:0016226)2.90874690
77NADH dehydrogenase complex assembly (GO:0010257)2.90284926
78mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.90284926
79mitochondrial respiratory chain complex I assembly (GO:0032981)2.90284926
80L-serine metabolic process (GO:0006563)2.87756382
81positive regulation of mitochondrial fission (GO:0090141)2.86193176
82viral mRNA export from host cell nucleus (GO:0046784)2.85362308
83ubiquinone metabolic process (GO:0006743)2.85069088
84establishment of protein localization to mitochondrion (GO:0072655)2.84285093
85nucleoside triphosphate biosynthetic process (GO:0009142)2.82544893
86transcription elongation from RNA polymerase III promoter (GO:0006385)2.80919707
87termination of RNA polymerase III transcription (GO:0006386)2.80919707
88inner mitochondrial membrane organization (GO:0007007)2.80219418
89protein localization to synapse (GO:0035418)2.80181082
90pseudouridine synthesis (GO:0001522)2.79697524
91DNA replication checkpoint (GO:0000076)2.78900684
92synaptic vesicle docking involved in exocytosis (GO:0016081)2.77799301
93DNA replication initiation (GO:0006270)2.77456114
94negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.74746011
95negative regulation of ligase activity (GO:0051352)2.74746011
96regulation of cellular amino acid metabolic process (GO:0006521)2.73851153
97proteasome assembly (GO:0043248)2.73832936
98nucleobase catabolic process (GO:0046113)2.72783422
99UTP biosynthetic process (GO:0006228)2.71962382
100DNA double-strand break processing (GO:0000729)2.70899736
101synaptic vesicle maturation (GO:0016188)2.70221437
102de novo posttranslational protein folding (GO:0051084)2.70167861
103regulation of protein heterodimerization activity (GO:0043497)2.70014382
104pyrimidine nucleotide catabolic process (GO:0006244)2.69764926
105anterograde synaptic vesicle transport (GO:0048490)2.69565001
106GMP metabolic process (GO:0046037)2.69053180
107deoxyribose phosphate biosynthetic process (GO:0046385)2.68521805
1082-deoxyribonucleotide biosynthetic process (GO:0009265)2.68521805
109peptidyl-arginine methylation (GO:0018216)2.67696249
110peptidyl-arginine N-methylation (GO:0035246)2.67696249
111branched-chain amino acid catabolic process (GO:0009083)2.67603629
112proton transport (GO:0015992)2.67603007
113regulation of cilium movement (GO:0003352)2.66281787
114pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.64950638
115positive regulation of TOR signaling (GO:0032008)2.64178950
116protein neddylation (GO:0045116)2.64119290
117platelet dense granule organization (GO:0060155)2.64101601
118establishment of viral latency (GO:0019043)2.64101211
119mitotic recombination (GO:0006312)2.64022626
120spliceosomal complex assembly (GO:0000245)2.63882437
121deoxyribonucleotide catabolic process (GO:0009264)2.63547154
122de novo protein folding (GO:0006458)2.62889080
123hydrogen transport (GO:0006818)2.62081678
124protein-cofactor linkage (GO:0018065)2.61535904
125mitochondrion transport along microtubule (GO:0047497)2.61125439
126establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.61125439
127signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.60819069
128signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.60819069
129signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.60819069
1307-methylguanosine mRNA capping (GO:0006370)2.60599496
131positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.60110664
132nucleobase-containing small molecule interconversion (GO:0015949)2.59813728
133intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.59676985
134nucleotide-excision repair, DNA gap filling (GO:0006297)2.58681885
135L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.58556189
136protein localization to mitochondrion (GO:0070585)2.58155764
137exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.56362070
138nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.55970657
139regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.55791391
140cellular component biogenesis (GO:0044085)2.55383850
141DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.55234597
142pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.54942005
143DNA unwinding involved in DNA replication (GO:0006268)2.54473769
144telomere maintenance via telomere lengthening (GO:0010833)2.54136168
145energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.54079718
146ATP hydrolysis coupled proton transport (GO:0015991)2.54079718
147mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.53242729
148neuron cell-cell adhesion (GO:0007158)2.53141292
149pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.52082492
150anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.51563374
151regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.49710491

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.68857781
2* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.33278646
3HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.72115397
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.58842925
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.52329783
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.30515745
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.16418123
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.05944644
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.03466944
10THAP11_20581084_ChIP-Seq_MESCs_Mouse2.96578907
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.92005558
12* EST1_17652178_ChIP-ChIP_JURKAT_Human2.91159570
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.83498996
14* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.57586086
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.49146961
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.47816373
17XRN2_22483619_ChIP-Seq_HELA_Human2.41433653
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.31199734
19EZH2_22144423_ChIP-Seq_EOC_Human2.30761791
20YY1_21170310_ChIP-Seq_MESCs_Mouse2.17250623
21E2F4_17652178_ChIP-ChIP_JURKAT_Human1.96056687
22* VDR_23849224_ChIP-Seq_CD4+_Human1.93159020
23FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.92649415
24* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.87312843
25DCP1A_22483619_ChIP-Seq_HELA_Human1.86267756
26GABP_19822575_ChIP-Seq_HepG2_Human1.85886834
27* SRF_21415370_ChIP-Seq_HL-1_Mouse1.85193433
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.85097018
29TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.84826142
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81279919
31* TTF2_22483619_ChIP-Seq_HELA_Human1.79058144
32* FOXP3_21729870_ChIP-Seq_TREG_Human1.78484478
33* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.76430140
34CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.75802320
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.75090168
36* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.73357976
37CIITA_25753668_ChIP-Seq_RAJI_Human1.72399882
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.67569482
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.65365395
40CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.62728682
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.62254706
42* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.60578501
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.59454818
44ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.57086368
45VDR_21846776_ChIP-Seq_THP-1_Human1.53527054
46SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.52921821
47CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.52312199
48DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.48727602
49* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.48607720
50ZNF274_21170338_ChIP-Seq_K562_Hela1.46486298
51CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.45469108
52MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.42596698
53FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.39271567
54FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.37326302
55* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.37011471
56* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36183881
57CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.33106299
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.32140447
59SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28414601
60* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27887619
61KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.26773744
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.25049119
63SOX2_16153702_ChIP-ChIP_HESCs_Human1.24527959
64MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.23363161
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.19809939
66EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.18482454
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18076286
68REST_18959480_ChIP-ChIP_MESCs_Mouse1.17780462
69TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16652864
70* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.14724505
71MYC_18940864_ChIP-ChIP_HL60_Human1.14367840
72MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13651156
73* YY1_22570637_ChIP-Seq_MALME-3M_Human1.11621937
74SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.10384955
75RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09153053
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08729858
77* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.07487516
78ELK1_19687146_ChIP-ChIP_HELA_Human1.06194270
79* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06124432
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.05757387
81E2F1_21310950_ChIP-Seq_MCF-7_Human1.04872642
82E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03291390
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.02425197
84POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01527443
85ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00160343
86PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98717764
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98593012
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.98327572
89CBX2_27304074_Chip-Seq_ESCs_Mouse0.97812448
90SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97154514
91BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96945109
92MYC_22102868_ChIP-Seq_BL_Human0.96474580
93DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95612502
94PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.94359345
95IKZF1_21737484_ChIP-ChIP_HCT116_Human0.94236362
96TET1_21451524_ChIP-Seq_MESCs_Mouse0.94172055
97ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94064598
98CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93585277
99RARB_27405468_Chip-Seq_BRAIN_Mouse0.93452213
100RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93233576
101PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92424603
102BCL6_27268052_Chip-Seq_Bcells_Human0.92188964
103PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.92020049
104* FOXP1_21924763_ChIP-Seq_HESCs_Human0.91716368
105CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.89901897
106SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.89402091
107ELK1_22589737_ChIP-Seq_MCF10A_Human0.88867408
108CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88848665
109HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.88157121
110EZH2_27304074_Chip-Seq_ESCs_Mouse0.87341120
111PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.86540338
112NANOG_18555785_ChIP-Seq_MESCs_Mouse0.85786340
113* ELF1_20517297_ChIP-Seq_JURKAT_Human0.85591676
114FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85352533
115IGF1R_20145208_ChIP-Seq_DFB_Human0.85266272
116KDM5A_27292631_Chip-Seq_BREAST_Human0.85091415
117TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.84369703
118* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.82908066
119NANOG_16153702_ChIP-ChIP_HESCs_Human0.81785749
120REST_21632747_ChIP-Seq_MESCs_Mouse0.81713573
121GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.79809123
122FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.77237748
123EWS_26573619_Chip-Seq_HEK293_Human0.76549950

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.81901174
2MP0001968_abnormal_touch/_nociception3.59262042
3MP0003880_abnormal_central_pattern3.18416992
4MP0002736_abnormal_nociception_after2.82741577
5MP0010030_abnormal_orbit_morphology2.73828381
6MP0003635_abnormal_synaptic_transmissio2.44435925
7MP0002822_catalepsy2.33126326
8MP0002734_abnormal_mechanical_nocicepti2.31555457
9MP0009046_muscle_twitch2.22306971
10MP0002735_abnormal_chemical_nociception2.22305144
11MP0002064_seizures2.15434449
12MP0002733_abnormal_thermal_nociception2.12725674
13MP0002272_abnormal_nervous_system2.12474899
14MP0000751_myopathy2.03352543
15MP0002234_abnormal_pharynx_morphology2.01589212
16MP0001529_abnormal_vocalization2.01574679
17MP0009745_abnormal_behavioral_response2.00100387
18MP0004270_analgesia1.99243291
19MP0001970_abnormal_pain_threshold1.96107235
20MP0003136_yellow_coat_color1.95473222
21MP0001986_abnormal_taste_sensitivity1.92374444
22MP0006276_abnormal_autonomic_nervous1.92063311
23MP0004142_abnormal_muscle_tone1.90716572
24MP0009379_abnormal_foot_pigmentation1.90689160
25MP0005423_abnormal_somatic_nervous1.87346284
26MP0004858_abnormal_nervous_system1.82268136
27MP0002063_abnormal_learning/memory/cond1.80361783
28MP0003186_abnormal_redox_activity1.76095980
29MP0002067_abnormal_sensory_capabilities1.71939169
30MP0001905_abnormal_dopamine_level1.68032835
31MP0002572_abnormal_emotion/affect_behav1.66154758
32MP0006072_abnormal_retinal_apoptosis1.63131048
33MP0003011_delayed_dark_adaptation1.60207219
34MP0001293_anophthalmia1.56615099
35MP0002751_abnormal_autonomic_nervous1.55647925
36MP0002396_abnormal_hematopoietic_system1.51147986
37MP0004147_increased_porphyrin_level1.50592122
38MP0004811_abnormal_neuron_physiology1.50312970
39MP0001188_hyperpigmentation1.48935900
40MP0002184_abnormal_innervation1.48520905
41MP0002653_abnormal_ependyma_morphology1.48287449
42MP0008932_abnormal_embryonic_tissue1.45493866
43MP0000049_abnormal_middle_ear1.43783442
44MP0005174_abnormal_tail_pigmentation1.43112165
45MP0003122_maternal_imprinting1.38694376
46MP0000778_abnormal_nervous_system1.35161822
47MP0008569_lethality_at_weaning1.33640329
48MP0000749_muscle_degeneration1.30983966
49MP0000015_abnormal_ear_pigmentation1.30074729
50MP0003123_paternal_imprinting1.29042916
51MP0002557_abnormal_social/conspecific_i1.28206302
52MP0003111_abnormal_nucleus_morphology1.24336910
53MP0010094_abnormal_chromosome_stability1.23953630
54MP0002095_abnormal_skin_pigmentation1.23179317
55MP0002837_dystrophic_cardiac_calcinosis1.22954979
56MP0005551_abnormal_eye_electrophysiolog1.18851670
57MP0005084_abnormal_gallbladder_morpholo1.16970970
58MP0000955_abnormal_spinal_cord1.16759209
59MP0000026_abnormal_inner_ear1.16433409
60MP0008260_abnormal_autophagy1.16322770
61MP0005253_abnormal_eye_physiology1.16245920
62MP0003315_abnormal_perineum_morphology1.16045832
63MP0008877_abnormal_DNA_methylation1.15644890
64MP0004957_abnormal_blastocyst_morpholog1.15283916
65MP0005171_absent_coat_pigmentation1.14618535
66MP0003693_abnormal_embryo_hatching1.13853691
67MP0006292_abnormal_olfactory_placode1.13559205
68MP0003938_abnormal_ear_development1.13332047
69MP0001486_abnormal_startle_reflex1.13118781
70MP0003077_abnormal_cell_cycle1.13076463
71MP0006036_abnormal_mitochondrial_physio1.11444897
72MP0000372_irregular_coat_pigmentation1.09204126
73MP0002882_abnormal_neuron_morphology1.09123801
74MP0004924_abnormal_behavior1.07621952
75MP0005386_behavior/neurological_phenoty1.07621952
76MP0003879_abnormal_hair_cell1.05717536
77MP0004145_abnormal_muscle_electrophysio1.05601159
78MP0005075_abnormal_melanosome_morpholog1.05434901
79MP0002066_abnormal_motor_capabilities/c1.04701544
80MP0005499_abnormal_olfactory_system1.04090916
81MP0005394_taste/olfaction_phenotype1.04090916
82MP0002233_abnormal_nose_morphology1.01713161
83MP0002638_abnormal_pupillary_reflex1.01620362
84MP0003283_abnormal_digestive_organ1.00253045
85MP0003172_abnormal_lysosome_physiology0.99540540
86MP0003787_abnormal_imprinting0.98206046
87MP0000920_abnormal_myelination0.98000820
88MP0002282_abnormal_trachea_morphology0.97066677
89MP0008058_abnormal_DNA_repair0.95661244
90MP0003634_abnormal_glial_cell0.94169901
91MP0008995_early_reproductive_senescence0.93280715
92MP0008789_abnormal_olfactory_epithelium0.91960398
93MP0003786_premature_aging0.91610522
94MP0003806_abnormal_nucleotide_metabolis0.91331279
95MP0000750_abnormal_muscle_regeneration0.91084252
96MP0002090_abnormal_vision0.89455966
97MP0000358_abnormal_cell_content/0.88443616
98MP0000631_abnormal_neuroendocrine_gland0.88440324
99MP0000516_abnormal_urinary_system0.88296457
100MP0005367_renal/urinary_system_phenotyp0.88296457
101MP0006035_abnormal_mitochondrial_morpho0.87387447
102MP0001440_abnormal_grooming_behavior0.87285780
103MP0005195_abnormal_posterior_eye0.85322484
104MP0004742_abnormal_vestibular_system0.83390755
105MP0003121_genomic_imprinting0.83193141
106MP0002152_abnormal_brain_morphology0.81373057
107MP0000747_muscle_weakness0.81320804
108MP0005391_vision/eye_phenotype0.81055955
109MP0001764_abnormal_homeostasis0.80921383
110MP0003137_abnormal_impulse_conducting0.80717467
111MP0004133_heterotaxia0.79421039
112MP0003656_abnormal_erythrocyte_physiolo0.78808919
113MP0002752_abnormal_somatic_nervous0.77225609
114MP0000681_abnormal_thyroid_gland0.75931478
115MP0004272_abnormal_basement_membrane0.75775035
116MP0001984_abnormal_olfaction0.75371310
117MP0003646_muscle_fatigue0.74733135
118MP0008007_abnormal_cellular_replicative0.74395138
119MP0003755_abnormal_palate_morphology0.74040463
120MP0004885_abnormal_endolymph0.73249990
121MP0001348_abnormal_lacrimal_gland0.71555409
122MP0002229_neurodegeneration0.71381191
123MP0003861_abnormal_nervous_system0.71330768
124MP0002069_abnormal_eating/drinking_beha0.70049235
125MP0001346_abnormal_lacrimal_gland0.69667372
126MP0005645_abnormal_hypothalamus_physiol0.69179684
127MP0001963_abnormal_hearing_physiology0.66684103
128MP0001324_abnormal_eye_pigmentation0.65907506
129MP0000313_abnormal_cell_death0.64821137
130MP0002938_white_spotting0.63573257
131MP0002102_abnormal_ear_morphology0.63569445
132MP0003631_nervous_system_phenotype0.63379789
133MP0005646_abnormal_pituitary_gland0.63263899
134MP0008872_abnormal_physiological_respon0.63239544
135MP0002089_abnormal_postnatal_growth/wei0.62972912

Predicted human phenotypes

RankGene SetZ-score
1Ulnar claw (HP:0001178)5.58031740
2Abnormality of cells of the erythroid lineage (HP:0012130)4.11887094
3Acute necrotizing encephalopathy (HP:0006965)4.07515349
4Impaired proprioception (HP:0010831)4.05520280
5Hepatocellular necrosis (HP:0001404)4.03998974
6Abnormal number of erythroid precursors (HP:0012131)4.03887512
7Myokymia (HP:0002411)3.94887818
8Mitochondrial inheritance (HP:0001427)3.94210328
9Abnormal mitochondria in muscle tissue (HP:0008316)3.91734877
10Segmental peripheral demyelination/remyelination (HP:0003481)3.75387351
11Cerebral edema (HP:0002181)3.54063487
12Insidious onset (HP:0003587)3.53282315
13Termporal pattern (HP:0011008)3.53282315
14Abnormality of the vocal cords (HP:0008777)3.46628098
15Increased CSF lactate (HP:0002490)3.35596504
16Action tremor (HP:0002345)3.27065551
17Progressive macrocephaly (HP:0004481)3.26933705
18Abnormality of the anterior horn cell (HP:0006802)3.24689978
19Degeneration of anterior horn cells (HP:0002398)3.24689978
20Focal motor seizures (HP:0011153)3.14548132
21Reticulocytopenia (HP:0001896)3.10626386
22Microvesicular hepatic steatosis (HP:0001414)3.10253145
23Hepatic necrosis (HP:0002605)3.05853931
24Decreased activity of mitochondrial respiratory chain (HP:0008972)3.00624157
25Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.00624157
26True hermaphroditism (HP:0010459)2.83233137
27Acute encephalopathy (HP:0006846)2.78023023
28Cerebral hypomyelination (HP:0006808)2.77167451
29Increased muscle lipid content (HP:0009058)2.69044851
30Medial flaring of the eyebrow (HP:0010747)2.66822266
31Gait imbalance (HP:0002141)2.66556485
32Retinal dysplasia (HP:0007973)2.65731033
33Visual hallucinations (HP:0002367)2.62098309
34Exercise intolerance (HP:0003546)2.59226208
35Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.55417107
36Pancreatic fibrosis (HP:0100732)2.53249747
37Atrophy/Degeneration involving motor neurons (HP:0007373)2.52301553
38Increased serum lactate (HP:0002151)2.51436194
39Abnormality of the labia minora (HP:0012880)2.50032960
40Aplastic anemia (HP:0001915)2.49214122
41Epileptic encephalopathy (HP:0200134)2.49093225
42Congenital primary aphakia (HP:0007707)2.47945241
43Pallor (HP:0000980)2.47317267
44Macrocytic anemia (HP:0001972)2.46211524
45Increased hepatocellular lipid droplets (HP:0006565)2.45631539
46Steppage gait (HP:0003376)2.42293761
47Nephrogenic diabetes insipidus (HP:0009806)2.40373930
48Peripheral hypomyelination (HP:0007182)2.40012156
49Upper limb muscle weakness (HP:0003484)2.40001328
50Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.39463663
51Hyperglycinemia (HP:0002154)2.38999620
52Neuroendocrine neoplasm (HP:0100634)2.37719667
53Postural tremor (HP:0002174)2.37518950
54Respiratory failure (HP:0002878)2.37473014
55Poor suck (HP:0002033)2.32485170
56Limb dystonia (HP:0002451)2.28616980
57Large eyes (HP:0001090)2.26208785
58Failure to thrive in infancy (HP:0001531)2.25946104
59Exercise-induced muscle cramps (HP:0003710)2.24276999
60Atonic seizures (HP:0010819)2.23011123
61Abnormality of midbrain morphology (HP:0002418)2.21014553
62Molar tooth sign on MRI (HP:0002419)2.21014553
63Pheochromocytoma (HP:0002666)2.17029189
64Sclerocornea (HP:0000647)2.16591862
65Emotional lability (HP:0000712)2.15554503
66Exertional dyspnea (HP:0002875)2.14459974
67Optic disc pallor (HP:0000543)2.13030401
68Methylmalonic aciduria (HP:0012120)2.10266418
69Thrombocytosis (HP:0001894)2.09527975
70Pancreatic cysts (HP:0001737)2.09081320
71Increased intramyocellular lipid droplets (HP:0012240)2.07931488
72Increased serum pyruvate (HP:0003542)2.07823201
73Abnormality of glycolysis (HP:0004366)2.07823201
74X-linked dominant inheritance (HP:0001423)2.05614970
75Abnormal hair whorl (HP:0010721)2.04773539
76CNS demyelination (HP:0007305)2.04545416
77Abnormal pupillary function (HP:0007686)2.03676486
78Aplasia/Hypoplasia of the sacrum (HP:0008517)2.02409815
79Lactic acidosis (HP:0003128)2.02220792
80Neoplasm of the peripheral nervous system (HP:0100007)2.02150243
81Lethargy (HP:0001254)2.01155988
82Type I transferrin isoform profile (HP:0003642)2.01041616
83Dicarboxylic aciduria (HP:0003215)2.00851475
84Abnormality of dicarboxylic acid metabolism (HP:0010995)2.00851475
85Foot dorsiflexor weakness (HP:0009027)1.97831061
86Neuroblastoma (HP:0003006)1.97333977
87Primitive neuroectodermal tumor (HP:0030065)1.97333977
88Neuroblastic tumors (HP:0004376)1.97333977
89Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.97333977
90Agnosia (HP:0010524)1.97058172
91Hemiparesis (HP:0001269)1.95938129
92Septo-optic dysplasia (HP:0100842)1.95541183
933-Methylglutaconic aciduria (HP:0003535)1.94799362
94Leukodystrophy (HP:0002415)1.94669489
95Renal Fanconi syndrome (HP:0001994)1.94394425
96Annular pancreas (HP:0001734)1.93964444
97Unsteady gait (HP:0002317)1.92141481
98Type 2 muscle fiber atrophy (HP:0003554)1.91231385
99Focal seizures (HP:0007359)1.90738568
100Aplasia/Hypoplasia of the tongue (HP:0010295)1.90471377
101Muscle fiber atrophy (HP:0100295)1.90375841
102Anencephaly (HP:0002323)1.89653904
103Abnormality of the lower motor neuron (HP:0002366)1.89234118
104Abnormality of the foot musculature (HP:0001436)1.88823292
105Abnormality of magnesium homeostasis (HP:0004921)1.88567969
106Hypothermia (HP:0002045)1.87985154
107Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.87478706
108Progressive microcephaly (HP:0000253)1.85116070
109Ankle clonus (HP:0011448)1.83989807
110Broad-based gait (HP:0002136)1.83586582
111Lipid accumulation in hepatocytes (HP:0006561)1.83005211
112Abnormal eating behavior (HP:0100738)1.82128585
113Severe visual impairment (HP:0001141)1.81705280
114Postnatal microcephaly (HP:0005484)1.80656440
115Lissencephaly (HP:0001339)1.79213266
116Respiratory difficulties (HP:0002880)1.78127913
117Hypoventilation (HP:0002791)1.78114222
118Vaginal atresia (HP:0000148)1.77556205
119Hypoplasia of the brainstem (HP:0002365)1.77001046
120Aplasia/Hypoplasia of the brainstem (HP:0007362)1.77001046
121Cholecystitis (HP:0001082)1.75572961
122Abnormal gallbladder physiology (HP:0012438)1.75572961
123Colon cancer (HP:0003003)1.75268120
124Mutism (HP:0002300)1.74723210
125Polyphagia (HP:0002591)1.74606644
126Generalized hypotonia (HP:0001290)1.74004892
127Occipital encephalocele (HP:0002085)1.73938372
128Sleep apnea (HP:0010535)1.73620666
129Amyotrophic lateral sclerosis (HP:0007354)1.72787134
130Papilledema (HP:0001085)1.72471114
131Decreased testicular size (HP:0008734)1.72187629
132Genital tract atresia (HP:0001827)1.71649631
133Febrile seizures (HP:0002373)1.68675839
134Hammertoe (HP:0001765)1.68504379
135Nephronophthisis (HP:0000090)1.68281286
136Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.68024607
137Abnormality of the motor neurons (HP:0002450)1.66175137
138Abnormal neuron morphology (HP:0012757)1.66175137
139Abnormality of the heme biosynthetic pathway (HP:0010472)1.65699377
140Methylmalonic acidemia (HP:0002912)1.65068822
141Blindness (HP:0000618)1.64524958
142Anophthalmia (HP:0000528)1.63792581
143Depression (HP:0000716)1.62107910
144Abnormal protein glycosylation (HP:0012346)1.61727865
145Abnormal glycosylation (HP:0012345)1.61727865
146Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.61727865
147Abnormal protein N-linked glycosylation (HP:0012347)1.61727865
148Insomnia (HP:0100785)1.61668999
149Poor eye contact (HP:0000817)1.61659717
150Abnormality of renal resorption (HP:0011038)1.61211318
151Pointed chin (HP:0000307)1.61010320
152Petechiae (HP:0000967)1.59997868
153Myotonia (HP:0002486)1.58899942
154Hypoplastic pelvis (HP:0008839)1.58892649
155Adrenal hypoplasia (HP:0000835)1.58306514
156Opisthotonus (HP:0002179)1.58241109
157Broad foot (HP:0001769)1.58099977

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK197.55503632
2VRK24.87301510
3BCKDK3.77571356
4TLK13.74903886
5STK162.94682125
6MAP3K122.92713954
7CASK2.61733866
8WNK32.30535361
9TRIM282.04613802
10BUB12.04533044
11CAMKK22.01405238
12SCYL21.99242319
13NUAK11.97646843
14DAPK11.87757117
15TESK21.85596902
16MAP4K21.79487464
17ARAF1.76349210
18NME21.72264003
19EPHB21.70794830
20ZAK1.70296304
21MINK11.66782521
22PIM21.66649443
23CSNK1G21.61946091
24UHMK11.61690246
25CCNB11.60666634
26LIMK11.60002961
27PRPF4B1.53260425
28BCR1.51256585
29VRK11.46163814
30CSNK1G11.36199830
31CSNK1A1L1.35900971
32MAP2K71.35578864
33EIF2AK11.33948885
34FES1.33589437
35DAPK31.32773555
36MARK11.31438559
37MAP3K101.24602325
38NME11.23574366
39NEK11.23522508
40NTRK31.19669491
41BRSK11.16795677
42BRAF1.14819201
43CDK11A1.13805942
44TSSK61.12745411
45CDC71.12648269
46PINK11.10750699
47SRPK11.10422880
48MAPK131.09552968
49TNIK1.04666883
50WEE11.04500804
51BLK1.03212410
52MYLK1.00063813
53KDR0.99867668
54CAMKK10.99469735
55PLK20.99379586
56CDK180.96349391
57ACVR1B0.95552990
58ILK0.94501972
59GRK50.93626668
60CDK140.90532852
61CDK150.90474834
62TAF10.90177743
63PRKD30.87794461
64MAP3K110.87025096
65TESK10.86473817
66EPHA40.85607108
67DAPK20.85288419
68MATK0.82022323
69MKNK10.79894120
70KIT0.79820168
71AURKA0.79420008
72SIK30.78834235
73PHKG10.78722242
74PHKG20.78722242
75PBK0.75413204
76CDK80.72652291
77TAOK20.72281803
78ABL20.72162560
79KSR10.70607140
80PKN10.69769320
81PAK40.68825280
82CDK50.66510143
83TIE10.66248097
84MAP3K90.64928875
85RPS6KA50.64167789
86MAP3K40.64088745
87MAP2K60.62439380
88OBSCN0.59646934
89MAPKAPK50.58371596
90ADRBK10.58240588
91ATR0.57542037
92TGFBR10.56386922
93PAK30.55447279
94PRKCG0.54496902
95CSNK1A10.52745752
96ADRBK20.52065969
97MAP2K40.51146113
98GRK10.51139285
99MKNK20.51050211
100MAP2K30.50932374
101CSNK1G30.50476986
102CAMK2G0.50317622
103BMPR1B0.47933272
104SYK0.46133879
105EPHA30.45741708
106CHEK20.45660812
107PAK10.45269242
108AURKB0.45215081
109BRSK20.44836498
110CAMK2B0.44004776
111RPS6KA20.43086135
112PRKCI0.42538277
113AKT20.41901759
114RIPK40.41832287
115DYRK1B0.41269384
116PAK60.41249828
117PRKCE0.40960187
118LRRK20.40784586
119PLK30.40664843
120PLK10.40024076
121IRAK20.39687268
122CSNK2A10.39554859
123PDK20.39522854
124CAMK2A0.39482348
125CAMK10.39019415
126MAPKAPK30.38772446
127EIF2AK30.38738497
128RAF10.38392520
129CSF1R0.38287776
130CDK70.37526923
131CSNK2A20.37491366
132DYRK20.37255156
133NTRK20.36642128
134CAMK2D0.36479332
135IRAK10.36456514
136YES10.35457528
137TNK20.34147158
138DYRK30.33966164
139BTK0.33565533
140ROCK20.33337211

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.98268577
2DNA replication_Homo sapiens_hsa030303.46565068
3Oxidative phosphorylation_Homo sapiens_hsa001903.24852296
4Parkinsons disease_Homo sapiens_hsa050123.07685883
5Proteasome_Homo sapiens_hsa030502.98706648
6Mismatch repair_Homo sapiens_hsa034302.76758095
7Synaptic vesicle cycle_Homo sapiens_hsa047212.53876078
8Fatty acid elongation_Homo sapiens_hsa000622.25563559
9Huntingtons disease_Homo sapiens_hsa050162.19195173
10Alzheimers disease_Homo sapiens_hsa050102.10259809
11RNA polymerase_Homo sapiens_hsa030202.09518569
12Base excision repair_Homo sapiens_hsa034102.04357000
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.01690849
14Spliceosome_Homo sapiens_hsa030401.98014824
15Homologous recombination_Homo sapiens_hsa034401.84938316
16Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.81104920
17Collecting duct acid secretion_Homo sapiens_hsa049661.77224655
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.75929672
19Nucleotide excision repair_Homo sapiens_hsa034201.75561643
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.69247009
21Pyrimidine metabolism_Homo sapiens_hsa002401.64155018
22Folate biosynthesis_Homo sapiens_hsa007901.61099697
23Cardiac muscle contraction_Homo sapiens_hsa042601.58382585
24Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.53992515
25Nicotine addiction_Homo sapiens_hsa050331.51242801
26Propanoate metabolism_Homo sapiens_hsa006401.47244109
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.44419546
28Carbon metabolism_Homo sapiens_hsa012001.41319536
29Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.39331199
30Vibrio cholerae infection_Homo sapiens_hsa051101.37951033
31Steroid biosynthesis_Homo sapiens_hsa001001.33577773
32Olfactory transduction_Homo sapiens_hsa047401.31355849
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.30609869
34Pyruvate metabolism_Homo sapiens_hsa006201.29966690
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.29433327
36Glutathione metabolism_Homo sapiens_hsa004801.28256839
37RNA transport_Homo sapiens_hsa030131.27969926
38Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.25524488
39Butanoate metabolism_Homo sapiens_hsa006501.15032367
40Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.13100976
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.11668768
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.10967592
43Alcoholism_Homo sapiens_hsa050341.09803538
44Morphine addiction_Homo sapiens_hsa050321.07442182
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.05482775
46Dopaminergic synapse_Homo sapiens_hsa047281.04045519
47Peroxisome_Homo sapiens_hsa041461.01214476
48Circadian entrainment_Homo sapiens_hsa047131.00952884
49Cell cycle_Homo sapiens_hsa041100.99777022
50Purine metabolism_Homo sapiens_hsa002300.98947216
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.95338435
52GABAergic synapse_Homo sapiens_hsa047270.94653352
53Oocyte meiosis_Homo sapiens_hsa041140.93964961
54Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93646678
55Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.89965042
56Long-term potentiation_Homo sapiens_hsa047200.89290616
57Pentose phosphate pathway_Homo sapiens_hsa000300.86621792
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.86545586
59Metabolic pathways_Homo sapiens_hsa011000.86338223
60Fructose and mannose metabolism_Homo sapiens_hsa000510.86237368
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85835872
62RNA degradation_Homo sapiens_hsa030180.85193784
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85126842
64Protein export_Homo sapiens_hsa030600.84404301
65Phagosome_Homo sapiens_hsa041450.83731443
66Fatty acid metabolism_Homo sapiens_hsa012120.83515255
67Cholinergic synapse_Homo sapiens_hsa047250.82067072
68Serotonergic synapse_Homo sapiens_hsa047260.81238099
69Fanconi anemia pathway_Homo sapiens_hsa034600.81217966
70Renin-angiotensin system_Homo sapiens_hsa046140.81007329
71Glutamatergic synapse_Homo sapiens_hsa047240.80580351
72N-Glycan biosynthesis_Homo sapiens_hsa005100.78853489
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76077970
74Amphetamine addiction_Homo sapiens_hsa050310.75877665
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.75665082
76Long-term depression_Homo sapiens_hsa047300.71672618
77Non-homologous end-joining_Homo sapiens_hsa034500.68870379
78beta-Alanine metabolism_Homo sapiens_hsa004100.68373493
79Taste transduction_Homo sapiens_hsa047420.67120086
80Gap junction_Homo sapiens_hsa045400.66322791
81Arginine and proline metabolism_Homo sapiens_hsa003300.65985347
82One carbon pool by folate_Homo sapiens_hsa006700.65238768
83Other glycan degradation_Homo sapiens_hsa005110.65179821
84Sulfur relay system_Homo sapiens_hsa041220.62316383
85Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62185763
86Systemic lupus erythematosus_Homo sapiens_hsa053220.61906999
87mRNA surveillance pathway_Homo sapiens_hsa030150.60406802
88Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.60241504
89Epstein-Barr virus infection_Homo sapiens_hsa051690.58391518
90Sulfur metabolism_Homo sapiens_hsa009200.57215169
91Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.56198983
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.55805626
93Basal cell carcinoma_Homo sapiens_hsa052170.53374652
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53187485
95Tryptophan metabolism_Homo sapiens_hsa003800.52558575
96Glioma_Homo sapiens_hsa052140.51595847
97Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51318007
98Shigellosis_Homo sapiens_hsa051310.49911286
99Hedgehog signaling pathway_Homo sapiens_hsa043400.49730368
100Oxytocin signaling pathway_Homo sapiens_hsa049210.48877901
101Calcium signaling pathway_Homo sapiens_hsa040200.48590978
102Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48292199
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.48088674
1042-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.45966667
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.45489264
106Basal transcription factors_Homo sapiens_hsa030220.44980843
107Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.44129243
108Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.43524752
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43507066
110Thyroid cancer_Homo sapiens_hsa052160.42532577
111Gastric acid secretion_Homo sapiens_hsa049710.41621463
112Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.41130998
113Phototransduction_Homo sapiens_hsa047440.40978082
114Primary bile acid biosynthesis_Homo sapiens_hsa001200.40558265
115Axon guidance_Homo sapiens_hsa043600.40494224
116Galactose metabolism_Homo sapiens_hsa000520.40475401
117Cyanoamino acid metabolism_Homo sapiens_hsa004600.40140203
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.38544617
119Insulin secretion_Homo sapiens_hsa049110.38339807
120VEGF signaling pathway_Homo sapiens_hsa043700.37885219
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37813911
122GnRH signaling pathway_Homo sapiens_hsa049120.36223235
123Fatty acid degradation_Homo sapiens_hsa000710.35861098
124African trypanosomiasis_Homo sapiens_hsa051430.35083532
125Salivary secretion_Homo sapiens_hsa049700.34289793
126Vitamin B6 metabolism_Homo sapiens_hsa007500.33974370
127Cocaine addiction_Homo sapiens_hsa050300.33664026
128Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.32763349
129Rheumatoid arthritis_Homo sapiens_hsa053230.32438297
130Non-small cell lung cancer_Homo sapiens_hsa052230.31936075
131Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.31511130
132Salmonella infection_Homo sapiens_hsa051320.31225613
133Colorectal cancer_Homo sapiens_hsa052100.31169296
134Asthma_Homo sapiens_hsa053100.30382663
135Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.30212509
136Regulation of autophagy_Homo sapiens_hsa041400.30039709
137Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27483112
138Biosynthesis of amino acids_Homo sapiens_hsa012300.27457304
139Melanoma_Homo sapiens_hsa052180.26118204
140Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.25939795
141Selenocompound metabolism_Homo sapiens_hsa004500.24695964
142Tyrosine metabolism_Homo sapiens_hsa003500.23355720

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