

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.27559457 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 4.43000132 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.43000132 |
| 4 | central nervous system myelination (GO:0022010) | 4.05936243 |
| 5 | axon ensheathment in central nervous system (GO:0032291) | 4.05936243 |
| 6 | protein complex biogenesis (GO:0070271) | 3.94526321 |
| 7 | respiratory electron transport chain (GO:0022904) | 3.83606595 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 3.83375275 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 3.79581079 |
| 10 | ribosomal small subunit biogenesis (GO:0042274) | 3.78907489 |
| 11 | electron transport chain (GO:0022900) | 3.77635429 |
| 12 | NADH dehydrogenase complex assembly (GO:0010257) | 3.77291146 |
| 13 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.77291146 |
| 14 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.77291146 |
| 15 | CENP-A containing nucleosome assembly (GO:0034080) | 3.74728114 |
| 16 | kinetochore organization (GO:0051383) | 3.69216359 |
| 17 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.67225042 |
| 18 | centriole replication (GO:0007099) | 3.66999084 |
| 19 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.66789881 |
| 20 | DNA ligation (GO:0006266) | 3.66497852 |
| 21 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.63142489 |
| 22 | chromatin remodeling at centromere (GO:0031055) | 3.62412120 |
| 23 | protein-cofactor linkage (GO:0018065) | 3.59325833 |
| 24 | meiotic chromosome segregation (GO:0045132) | 3.36882017 |
| 25 | intraciliary transport (GO:0042073) | 3.28397532 |
| 26 | respiratory chain complex IV assembly (GO:0008535) | 3.27194975 |
| 27 | neural tube formation (GO:0001841) | 3.22542193 |
| 28 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.21995721 |
| 29 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.21995721 |
| 30 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.21995721 |
| 31 | DNA damage response, detection of DNA damage (GO:0042769) | 3.18930375 |
| 32 | regulation of helicase activity (GO:0051095) | 3.18072510 |
| 33 | microtubule polymerization or depolymerization (GO:0031109) | 3.16854149 |
| 34 | inner mitochondrial membrane organization (GO:0007007) | 3.13000654 |
| 35 | cytochrome complex assembly (GO:0017004) | 3.11110889 |
| 36 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.10794640 |
| 37 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.10548659 |
| 38 | RNA-dependent DNA replication (GO:0006278) | 3.09962624 |
| 39 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.07484807 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.07269406 |
| 41 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.07269406 |
| 42 | positive regulation of chromosome segregation (GO:0051984) | 3.05096334 |
| 43 | kinetochore assembly (GO:0051382) | 3.02901901 |
| 44 | telomere maintenance via telomerase (GO:0007004) | 3.01736283 |
| 45 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.97832905 |
| 46 | DNA replication-independent nucleosome organization (GO:0034724) | 2.97832905 |
| 47 | histone exchange (GO:0043486) | 2.96331229 |
| 48 | microtubule depolymerization (GO:0007019) | 2.91987441 |
| 49 | viral transcription (GO:0019083) | 2.91003553 |
| 50 | DNA deamination (GO:0045006) | 2.89811482 |
| 51 | epithelial cilium movement (GO:0003351) | 2.89710508 |
| 52 | translational termination (GO:0006415) | 2.89063778 |
| 53 | cotranslational protein targeting to membrane (GO:0006613) | 2.87848288 |
| 54 | maturation of SSU-rRNA (GO:0030490) | 2.86192990 |
| 55 | regulation of DNA endoreduplication (GO:0032875) | 2.86174315 |
| 56 | regulation of sister chromatid cohesion (GO:0007063) | 2.84969993 |
| 57 | translational elongation (GO:0006414) | 2.84345485 |
| 58 | histone H3-K4 trimethylation (GO:0080182) | 2.83845789 |
| 59 | protein neddylation (GO:0045116) | 2.82666853 |
| 60 | fatty acid elongation (GO:0030497) | 2.81887868 |
| 61 | DNA double-strand break processing (GO:0000729) | 2.80958843 |
| 62 | nuclear pore complex assembly (GO:0051292) | 2.80572423 |
| 63 | mitotic sister chromatid cohesion (GO:0007064) | 2.79964252 |
| 64 | metaphase plate congression (GO:0051310) | 2.78995093 |
| 65 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.77674509 |
| 66 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.77223456 |
| 67 | termination of RNA polymerase III transcription (GO:0006386) | 2.77223456 |
| 68 | protein targeting to ER (GO:0045047) | 2.76957746 |
| 69 | proteasome assembly (GO:0043248) | 2.76076491 |
| 70 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.75342852 |
| 71 | intracellular protein transmembrane import (GO:0044743) | 2.72448774 |
| 72 | centriole assembly (GO:0098534) | 2.72322713 |
| 73 | protein localization to cilium (GO:0061512) | 2.71774005 |
| 74 | synapsis (GO:0007129) | 2.71266449 |
| 75 | kidney morphogenesis (GO:0060993) | 2.70361879 |
| 76 | positive regulation of cellular amine metabolic process (GO:0033240) | 2.69054990 |
| 77 | translational initiation (GO:0006413) | 2.68986873 |
| 78 | GPI anchor biosynthetic process (GO:0006506) | 2.68014194 |
| 79 | cellular protein complex disassembly (GO:0043624) | 2.67766796 |
| 80 | ribosomal large subunit biogenesis (GO:0042273) | 2.66650268 |
| 81 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.66375460 |
| 82 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.66375460 |
| 83 | maturation of 5.8S rRNA (GO:0000460) | 2.66357750 |
| 84 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.66263268 |
| 85 | behavioral response to nicotine (GO:0035095) | 2.66223896 |
| 86 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.65809937 |
| 87 | protein localization to endoplasmic reticulum (GO:0070972) | 2.65668309 |
| 88 | regulation of meiosis I (GO:0060631) | 2.65603422 |
| 89 | response to pheromone (GO:0019236) | 2.65491885 |
| 90 | histone H2B ubiquitination (GO:0033523) | 2.64144387 |
| 91 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.61347202 |
| 92 | piRNA metabolic process (GO:0034587) | 2.61210278 |
| 93 | cullin deneddylation (GO:0010388) | 2.58800467 |
| 94 | pore complex assembly (GO:0046931) | 2.57855696 |
| 95 | DNA unwinding involved in DNA replication (GO:0006268) | 2.57568307 |
| 96 | single strand break repair (GO:0000012) | 2.56838792 |
| 97 | viral life cycle (GO:0019058) | 2.56549339 |
| 98 | intra-S DNA damage checkpoint (GO:0031573) | 2.56473131 |
| 99 | reciprocal DNA recombination (GO:0035825) | 2.54940523 |
| 100 | reciprocal meiotic recombination (GO:0007131) | 2.54940523 |
| 101 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.54908035 |
| 102 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.54664798 |
| 103 | protein K6-linked ubiquitination (GO:0085020) | 2.54653837 |
| 104 | regulation of mitochondrial translation (GO:0070129) | 2.54565724 |
| 105 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.53719330 |
| 106 | definitive hemopoiesis (GO:0060216) | 2.53494739 |
| 107 | establishment of integrated proviral latency (GO:0075713) | 2.53441718 |
| 108 | nuclear pore organization (GO:0006999) | 2.52178714 |
| 109 | non-recombinational repair (GO:0000726) | 2.51926925 |
| 110 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.51926925 |
| 111 | mitotic recombination (GO:0006312) | 2.50567987 |
| 112 | rRNA modification (GO:0000154) | 2.50357117 |
| 113 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.49686033 |
| 114 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.49345270 |
| 115 | translation (GO:0006412) | 2.48835441 |
| 116 | somite development (GO:0061053) | 2.47161337 |
| 117 | otic vesicle formation (GO:0030916) | 2.46836911 |
| 118 | mismatch repair (GO:0006298) | 2.46363177 |
| 119 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.46028075 |
| 120 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.46028075 |
| 121 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.46028075 |
| 122 | hydrogen ion transmembrane transport (GO:1902600) | 2.45828913 |
| 123 | GPI anchor metabolic process (GO:0006505) | 2.45654891 |
| 124 | regulation of histone H3-K9 methylation (GO:0051570) | 2.45025423 |
| 125 | ncRNA catabolic process (GO:0034661) | 2.44339976 |
| 126 | replication fork processing (GO:0031297) | 2.44099652 |
| 127 | retinal cone cell development (GO:0046549) | 2.43388555 |
| 128 | 7-methylguanosine RNA capping (GO:0009452) | 2.41992026 |
| 129 | RNA capping (GO:0036260) | 2.41992026 |
| 130 | regulation of cilium movement (GO:0003352) | 2.40894630 |
| 131 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.40607936 |
| 132 | nonmotile primary cilium assembly (GO:0035058) | 2.40349860 |
| 133 | DNA replication checkpoint (GO:0000076) | 2.40197166 |
| 134 | resolution of meiotic recombination intermediates (GO:0000712) | 2.40096153 |
| 135 | mitotic metaphase plate congression (GO:0007080) | 2.39954235 |
| 136 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.38896237 |
| 137 | mitotic G2/M transition checkpoint (GO:0044818) | 2.38470016 |
| 138 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.38382291 |
| 139 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.38382291 |
| 140 | peptidyl-lysine trimethylation (GO:0018023) | 2.38055789 |
| 141 | DNA topological change (GO:0006265) | 2.38051039 |
| 142 | mitotic chromosome condensation (GO:0007076) | 2.37785761 |
| 143 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.37601913 |
| 144 | microtubule anchoring (GO:0034453) | 2.37034180 |
| 145 | regulation of mitotic spindle organization (GO:0060236) | 2.36485961 |
| 146 | telomere maintenance via recombination (GO:0000722) | 2.35406185 |
| 147 | positive regulation of histone methylation (GO:0031062) | 2.34691761 |
| 148 | establishment of viral latency (GO:0019043) | 2.34638832 |
| 149 | DNA replication initiation (GO:0006270) | 2.34360349 |
| 150 | recombinational repair (GO:0000725) | 2.33254193 |
| 151 | double-strand break repair via homologous recombination (GO:0000724) | 2.32971224 |
| 152 | establishment of chromosome localization (GO:0051303) | 2.32187615 |
| 153 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.31676768 |
| 154 | telomere organization (GO:0032200) | 2.30799372 |
| 155 | histone mRNA metabolic process (GO:0008334) | 2.30243460 |
| 156 | sister chromatid cohesion (GO:0007062) | 2.29219887 |
| 157 | regulation of spindle organization (GO:0090224) | 2.29137092 |
| 158 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.28687913 |
| 159 | 7-methylguanosine mRNA capping (GO:0006370) | 2.27730652 |
| 160 | viral mRNA export from host cell nucleus (GO:0046784) | 2.27657181 |
| 161 | telomere maintenance (GO:0000723) | 2.27531513 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.65641419 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.85593821 |
| 3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.15112323 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.13091674 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.09560154 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.84270972 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.82824574 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.77373082 |
| 9 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.73647041 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.60135916 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.54165060 |
| 12 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45950355 |
| 13 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.37323785 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.37286740 |
| 15 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.33765987 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 2.30307413 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.26974514 |
| 18 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.26346389 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.19060885 |
| 20 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.15730989 |
| 21 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.11185162 |
| 22 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.10551572 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.06503991 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 2.04679244 |
| 25 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.03517094 |
| 26 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.93097357 |
| 27 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.87190810 |
| 28 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.82690810 |
| 29 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.82012139 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.77757711 |
| 31 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.73677004 |
| 32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.70503731 |
| 33 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.69920171 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.69633426 |
| 35 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.66932302 |
| 36 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.61628691 |
| 37 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.60535835 |
| 38 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.59711101 |
| 39 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.59275542 |
| 40 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.58731525 |
| 41 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.52289731 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.47241514 |
| 43 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.46531338 |
| 44 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.45526426 |
| 45 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.45304537 |
| 46 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.45304537 |
| 47 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.45304537 |
| 48 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.43929934 |
| 49 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.42352187 |
| 50 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.42191562 |
| 51 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.41919285 |
| 52 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.41863897 |
| 53 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.41479020 |
| 54 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.40689491 |
| 55 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.40671070 |
| 56 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.36669400 |
| 57 | * IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.36604982 |
| 58 | * CBP_20019798_ChIP-Seq_JUKART_Human | 1.36604982 |
| 59 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.35697914 |
| 60 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.34209923 |
| 61 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.32989773 |
| 62 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.32822174 |
| 63 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.30324606 |
| 64 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.30324606 |
| 65 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.29903442 |
| 66 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.26632230 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.26411971 |
| 68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.25708437 |
| 69 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.24556222 |
| 70 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.23516465 |
| 71 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.23322838 |
| 72 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.22882900 |
| 73 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.22377833 |
| 74 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.21703289 |
| 75 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.21381101 |
| 76 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.20957731 |
| 77 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.19654050 |
| 78 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.19413341 |
| 79 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.19194059 |
| 80 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.18876234 |
| 81 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.18642811 |
| 82 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18642146 |
| 83 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.18160688 |
| 84 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.17619801 |
| 85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.17095450 |
| 86 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.16630899 |
| 87 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.16006405 |
| 88 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.15803682 |
| 89 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15789981 |
| 90 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.15629263 |
| 91 | P300_19829295_ChIP-Seq_ESCs_Human | 1.15072507 |
| 92 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.14373489 |
| 93 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.14322294 |
| 94 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.13791223 |
| 95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.13725014 |
| 96 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.13542837 |
| 97 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.12208594 |
| 98 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.12073701 |
| 99 | TCF4_23295773_ChIP-Seq_U87_Human | 1.10095026 |
| 100 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.09590552 |
| 101 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.09333511 |
| 102 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.09325429 |
| 103 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.09126595 |
| 104 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.08996344 |
| 105 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.08690627 |
| 106 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.08648644 |
| 107 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.07729807 |
| 108 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.07447404 |
| 109 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.07024283 |
| 110 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06708755 |
| 111 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06708755 |
| 112 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.05843452 |
| 113 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.05204359 |
| 114 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.05126452 |
| 115 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.04564075 |
| 116 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.04089411 |
| 117 | STAT3_23295773_ChIP-Seq_U87_Human | 1.03996534 |
| 118 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.02643733 |
| 119 | * TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.02602474 |
| 120 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.02177663 |
| 121 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.01953172 |
| 122 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.01460802 |
| 123 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.00849937 |
| 124 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.00389940 |
| 125 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.00050035 |
| 126 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.00050035 |
| 127 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00030225 |
| 128 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99626308 |
| 129 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.99267123 |
| 130 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.98059959 |
| 131 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.97945671 |
| 132 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.97756379 |
| 133 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.97583327 |
| 134 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.97074338 |
| 135 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.96785891 |
| 136 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.95875374 |
| 137 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.95206934 |
| 138 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.94801310 |
| 139 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.94548499 |
| 140 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.92307758 |
| 141 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.91371853 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 4.86044151 |
| 2 | MP0003136_yellow_coat_color | 4.29415894 |
| 3 | MP0002009_preneoplasia | 4.17983041 |
| 4 | MP0003950_abnormal_plasma_membrane | 3.47119047 |
| 5 | MP0005409_darkened_coat_color | 3.06779068 |
| 6 | MP0008877_abnormal_DNA_methylation | 3.02366661 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.96501321 |
| 8 | MP0009697_abnormal_copulation | 2.67800007 |
| 9 | MP0010094_abnormal_chromosome_stability | 2.53635452 |
| 10 | MP0008058_abnormal_DNA_repair | 2.28775161 |
| 11 | MP0000569_abnormal_digit_pigmentation | 2.23758282 |
| 12 | MP0002102_abnormal_ear_morphology | 2.17143674 |
| 13 | MP0002166_altered_tumor_susceptibility | 2.12760477 |
| 14 | MP0003077_abnormal_cell_cycle | 2.03628084 |
| 15 | MP0008789_abnormal_olfactory_epithelium | 2.03219056 |
| 16 | MP0003787_abnormal_imprinting | 2.02939313 |
| 17 | MP0004381_abnormal_hair_follicle | 2.01835135 |
| 18 | MP0001986_abnormal_taste_sensitivity | 2.00258925 |
| 19 | MP0001984_abnormal_olfaction | 1.99083873 |
| 20 | MP0003693_abnormal_embryo_hatching | 1.97535799 |
| 21 | MP0005171_absent_coat_pigmentation | 1.94202705 |
| 22 | MP0004147_increased_porphyrin_level | 1.91817107 |
| 23 | MP0002837_dystrophic_cardiac_calcinosis | 1.83759833 |
| 24 | MP0004885_abnormal_endolymph | 1.80704140 |
| 25 | MP0004957_abnormal_blastocyst_morpholog | 1.74458621 |
| 26 | MP0003880_abnormal_central_pattern | 1.74163270 |
| 27 | MP0002006_tumorigenesis | 1.73733683 |
| 28 | MP0003724_increased_susceptibility_to | 1.73298165 |
| 29 | MP0005551_abnormal_eye_electrophysiolog | 1.68023236 |
| 30 | MP0002277_abnormal_respiratory_mucosa | 1.66896577 |
| 31 | MP0001293_anophthalmia | 1.66766195 |
| 32 | MP0002638_abnormal_pupillary_reflex | 1.63540650 |
| 33 | MP0005499_abnormal_olfactory_system | 1.63322117 |
| 34 | MP0005394_taste/olfaction_phenotype | 1.63322117 |
| 35 | MP0003111_abnormal_nucleus_morphology | 1.60800747 |
| 36 | MP0005174_abnormal_tail_pigmentation | 1.58858401 |
| 37 | MP0003718_maternal_effect | 1.58677621 |
| 38 | MP0000631_abnormal_neuroendocrine_gland | 1.58127524 |
| 39 | MP0002396_abnormal_hematopoietic_system | 1.55263635 |
| 40 | MP0002163_abnormal_gland_morphology | 1.54618518 |
| 41 | MP0001485_abnormal_pinna_reflex | 1.53470091 |
| 42 | MP0003121_genomic_imprinting | 1.51783669 |
| 43 | MP0001188_hyperpigmentation | 1.51444195 |
| 44 | MP0005379_endocrine/exocrine_gland_phen | 1.50844914 |
| 45 | MP0004142_abnormal_muscle_tone | 1.50224128 |
| 46 | MP0005408_hypopigmentation | 1.47909500 |
| 47 | MP0002095_abnormal_skin_pigmentation | 1.45079905 |
| 48 | MP0002736_abnormal_nociception_after | 1.40853531 |
| 49 | MP0000920_abnormal_myelination | 1.38113950 |
| 50 | MP0006276_abnormal_autonomic_nervous | 1.34844684 |
| 51 | MP0000383_abnormal_hair_follicle | 1.34037414 |
| 52 | MP0005646_abnormal_pituitary_gland | 1.31779985 |
| 53 | MP0006072_abnormal_retinal_apoptosis | 1.30783206 |
| 54 | MP0005075_abnormal_melanosome_morpholog | 1.28597064 |
| 55 | MP0000372_irregular_coat_pigmentation | 1.26688881 |
| 56 | MP0002160_abnormal_reproductive_system | 1.24874804 |
| 57 | MP0003937_abnormal_limbs/digits/tail_de | 1.24307384 |
| 58 | MP0008932_abnormal_embryonic_tissue | 1.23926395 |
| 59 | MP0005671_abnormal_response_to | 1.23899735 |
| 60 | MP0002938_white_spotting | 1.22996802 |
| 61 | MP0008995_early_reproductive_senescence | 1.20899181 |
| 62 | MP0003195_calcinosis | 1.20798773 |
| 63 | MP0002272_abnormal_nervous_system | 1.19809980 |
| 64 | MP0003011_delayed_dark_adaptation | 1.19559609 |
| 65 | MP0002928_abnormal_bile_duct | 1.18329877 |
| 66 | MP0001486_abnormal_startle_reflex | 1.18023023 |
| 67 | MP0003186_abnormal_redox_activity | 1.17453719 |
| 68 | MP0003122_maternal_imprinting | 1.17257312 |
| 69 | MP0002132_abnormal_respiratory_system | 1.16586006 |
| 70 | MP0000778_abnormal_nervous_system | 1.16575771 |
| 71 | MP0001851_eye_inflammation | 1.15916935 |
| 72 | MP0003690_abnormal_glial_cell | 1.15758092 |
| 73 | MP0003878_abnormal_ear_physiology | 1.15654410 |
| 74 | MP0005377_hearing/vestibular/ear_phenot | 1.15654410 |
| 75 | MP0003786_premature_aging | 1.15541888 |
| 76 | MP0001324_abnormal_eye_pigmentation | 1.14596008 |
| 77 | MP0002234_abnormal_pharynx_morphology | 1.13956329 |
| 78 | MP0002653_abnormal_ependyma_morphology | 1.13021709 |
| 79 | MP0001968_abnormal_touch/_nociception | 1.12899870 |
| 80 | MP0001529_abnormal_vocalization | 1.11643731 |
| 81 | MP0009046_muscle_twitch | 1.08960926 |
| 82 | MP0001835_abnormal_antigen_presentation | 1.07753021 |
| 83 | MP0009745_abnormal_behavioral_response | 1.07034471 |
| 84 | MP0000427_abnormal_hair_cycle | 1.06447672 |
| 85 | MP0003763_abnormal_thymus_physiology | 1.05455629 |
| 86 | MP0010678_abnormal_skin_adnexa | 1.05058221 |
| 87 | MP0004133_heterotaxia | 1.04106798 |
| 88 | MP0003938_abnormal_ear_development | 1.03410834 |
| 89 | MP0003941_abnormal_skin_development | 1.02290609 |
| 90 | MP0000566_synostosis | 1.01008345 |
| 91 | MP0005195_abnormal_posterior_eye | 1.00689122 |
| 92 | MP0003567_abnormal_fetal_cardiomyocyte | 1.00521444 |
| 93 | MP0006036_abnormal_mitochondrial_physio | 0.98871261 |
| 94 | MP0003806_abnormal_nucleotide_metabolis | 0.98506099 |
| 95 | MP0001800_abnormal_humoral_immune | 0.96590328 |
| 96 | MP0002752_abnormal_somatic_nervous | 0.95777402 |
| 97 | MP0006035_abnormal_mitochondrial_morpho | 0.93480891 |
| 98 | MP0001919_abnormal_reproductive_system | 0.92961183 |
| 99 | MP0001346_abnormal_lacrimal_gland | 0.92924603 |
| 100 | MP0001186_pigmentation_phenotype | 0.92687560 |
| 101 | MP0005253_abnormal_eye_physiology | 0.92243129 |
| 102 | MP0005391_vision/eye_phenotype | 0.92190124 |
| 103 | MP0002751_abnormal_autonomic_nervous | 0.91479349 |
| 104 | MP0001661_extended_life_span | 0.91108915 |
| 105 | MP0002148_abnormal_hypersensitivity_rea | 0.90773717 |
| 106 | MP0010307_abnormal_tumor_latency | 0.90615467 |
| 107 | MP0001286_abnormal_eye_development | 0.90605032 |
| 108 | MP0008007_abnormal_cellular_replicative | 0.90040302 |
| 109 | MP0002723_abnormal_immune_serum | 0.88951925 |
| 110 | MP0000465_gastrointestinal_hemorrhage | 0.87727651 |
| 111 | MP0003119_abnormal_digestive_system | 0.87268886 |
| 112 | MP0004264_abnormal_extraembryonic_tissu | 0.85529610 |
| 113 | MP0002233_abnormal_nose_morphology | 0.84494656 |
| 114 | MP0003698_abnormal_male_reproductive | 0.84404112 |
| 115 | MP0009785_altered_susceptibility_to | 0.84391386 |
| 116 | MP0004742_abnormal_vestibular_system | 0.84384637 |
| 117 | MP0000015_abnormal_ear_pigmentation | 0.84337068 |
| 118 | MP0005084_abnormal_gallbladder_morpholo | 0.83150402 |
| 119 | MP0001929_abnormal_gametogenesis | 0.81539784 |
| 120 | MP0002075_abnormal_coat/hair_pigmentati | 0.80990165 |
| 121 | MP0002067_abnormal_sensory_capabilities | 0.80575866 |
| 122 | MP0005000_abnormal_immune_tolerance | 0.80514847 |
| 123 | MP0005386_behavior/neurological_phenoty | 0.78817720 |
| 124 | MP0004924_abnormal_behavior | 0.78817720 |
| 125 | MP0002210_abnormal_sex_determination | 0.78541214 |
| 126 | MP0001905_abnormal_dopamine_level | 0.77361907 |
| 127 | MP0002557_abnormal_social/conspecific_i | 0.77075947 |
| 128 | MP0002420_abnormal_adaptive_immunity | 0.76068860 |
| 129 | MP0005389_reproductive_system_phenotype | 0.74714311 |
| 130 | MP0004145_abnormal_muscle_electrophysio | 0.74611618 |
| 131 | MP0000026_abnormal_inner_ear | 0.74474251 |
| 132 | MP0002090_abnormal_vision | 0.74429478 |
| 133 | MP0000647_abnormal_sebaceous_gland | 0.74413917 |
| 134 | MP0003828_pulmonary_edema | 0.74064249 |
| 135 | MP0000462_abnormal_digestive_system | 0.73573136 |
| 136 | MP0001764_abnormal_homeostasis | 0.72672685 |
| 137 | MP0001819_abnormal_immune_cell | 0.72416190 |
| 138 | MP0000689_abnormal_spleen_morphology | 0.72080031 |
| 139 | MP0002419_abnormal_innate_immunity | 0.71618127 |
| 140 | MP0008872_abnormal_physiological_respon | 0.70313369 |
| 141 | MP0002452_abnormal_antigen_presenting | 0.70185955 |
| 142 | MP0006292_abnormal_olfactory_placode | 0.69633043 |
| 143 | MP0005025_abnormal_response_to | 0.67227366 |
| 144 | MP0002722_abnormal_immune_system | 0.65874203 |
| 145 | MP0002398_abnormal_bone_marrow | 0.64090623 |
| 146 | MP0000432_abnormal_head_morphology | 0.63526710 |
| 147 | MP0000516_abnormal_urinary_system | 0.63258120 |
| 148 | MP0005367_renal/urinary_system_phenotyp | 0.63258120 |
| 149 | MP0001145_abnormal_male_reproductive | 0.63115212 |
| 150 | MP0000716_abnormal_immune_system | 0.61823047 |
| 151 | MP0002098_abnormal_vibrissa_morphology | 0.61702175 |
| 152 | MP0003890_abnormal_embryonic-extraembry | 0.60955309 |
| 153 | MP0002405_respiratory_system_inflammati | 0.60866137 |
| 154 | MP0000653_abnormal_sex_gland | 0.60122970 |
| 155 | MP0000762_abnormal_tongue_morphology | 0.59429108 |
| 156 | MP0000703_abnormal_thymus_morphology | 0.57569095 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromsome breakage (HP:0040012) | 3.94759920 |
| 2 | Nephronophthisis (HP:0000090) | 3.41389066 |
| 3 | Parakeratosis (HP:0001036) | 3.28368121 |
| 4 | Acute encephalopathy (HP:0006846) | 3.27640039 |
| 5 | Volvulus (HP:0002580) | 3.19332637 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.18234231 |
| 7 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.16652573 |
| 8 | Abnormality of the renal medulla (HP:0100957) | 3.01396684 |
| 9 | Abnormality of the renal cortex (HP:0011035) | 2.97393607 |
| 10 | Fair hair (HP:0002286) | 2.91587289 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 2.88632535 |
| 12 | Asplenia (HP:0001746) | 2.87318936 |
| 13 | Supernumerary spleens (HP:0009799) | 2.84711402 |
| 14 | Abnormal ciliary motility (HP:0012262) | 2.84463153 |
| 15 | Chronic hepatic failure (HP:0100626) | 2.81537122 |
| 16 | Reticulocytopenia (HP:0001896) | 2.81115976 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 2.72741286 |
| 18 | Abnormality of chromosome stability (HP:0003220) | 2.70113018 |
| 19 | Septo-optic dysplasia (HP:0100842) | 2.69113287 |
| 20 | Hepatocellular necrosis (HP:0001404) | 2.64372312 |
| 21 | Duplicated collecting system (HP:0000081) | 2.63624051 |
| 22 | Patchy hypopigmentation of hair (HP:0011365) | 2.62103927 |
| 23 | Renal Fanconi syndrome (HP:0001994) | 2.59009126 |
| 24 | Abnormality of the renal collecting system (HP:0004742) | 2.55004739 |
| 25 | Birth length less than 3rd percentile (HP:0003561) | 2.51446798 |
| 26 | Lipid accumulation in hepatocytes (HP:0006561) | 2.51408344 |
| 27 | Congenital, generalized hypertrichosis (HP:0004540) | 2.51025633 |
| 28 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.48749622 |
| 29 | Methylmalonic acidemia (HP:0002912) | 2.46950328 |
| 30 | Abnormality of the labia minora (HP:0012880) | 2.43696106 |
| 31 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.43577602 |
| 32 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.42731470 |
| 33 | White forelock (HP:0002211) | 2.42508928 |
| 34 | Hepatic necrosis (HP:0002605) | 2.38065875 |
| 35 | Generalized hypopigmentation of hair (HP:0011358) | 2.37033823 |
| 36 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.36602537 |
| 37 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.36602537 |
| 38 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.36104160 |
| 39 | Cerebral edema (HP:0002181) | 2.36075608 |
| 40 | Autoamputation (HP:0001218) | 2.34824069 |
| 41 | Lip pit (HP:0100267) | 2.32043270 |
| 42 | Absent/shortened dynein arms (HP:0200106) | 2.31186962 |
| 43 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.31186962 |
| 44 | Hypochromic microcytic anemia (HP:0004840) | 2.29509844 |
| 45 | Abnormality of midbrain morphology (HP:0002418) | 2.26778162 |
| 46 | Molar tooth sign on MRI (HP:0002419) | 2.26778162 |
| 47 | Abnormality of the preputium (HP:0100587) | 2.26460092 |
| 48 | Oligodactyly (hands) (HP:0001180) | 2.26072903 |
| 49 | Abnormality of the axillary hair (HP:0100134) | 2.25740826 |
| 50 | Abnormality of secondary sexual hair (HP:0009888) | 2.25740826 |
| 51 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.23156409 |
| 52 | 11 pairs of ribs (HP:0000878) | 2.22463725 |
| 53 | Congenital stationary night blindness (HP:0007642) | 2.18220368 |
| 54 | Leukodystrophy (HP:0002415) | 2.16255951 |
| 55 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.15713845 |
| 56 | Abnormality of the ileum (HP:0001549) | 2.14503838 |
| 57 | Renal cortical cysts (HP:0000803) | 2.14154221 |
| 58 | Sclerocornea (HP:0000647) | 2.13633558 |
| 59 | Gait imbalance (HP:0002141) | 2.12678937 |
| 60 | Congenital hepatic fibrosis (HP:0002612) | 2.11564025 |
| 61 | Congenital primary aphakia (HP:0007707) | 2.09167024 |
| 62 | Stenosis of the external auditory canal (HP:0000402) | 2.08659943 |
| 63 | Ectropion (HP:0000656) | 2.07406650 |
| 64 | Cystic liver disease (HP:0006706) | 2.06978592 |
| 65 | Median cleft lip (HP:0000161) | 2.05176181 |
| 66 | Abnormal number of erythroid precursors (HP:0012131) | 2.03829933 |
| 67 | Abnormality of the columella (HP:0009929) | 2.02260655 |
| 68 | Hypothermia (HP:0002045) | 2.00952083 |
| 69 | Microvesicular hepatic steatosis (HP:0001414) | 2.00847136 |
| 70 | Anencephaly (HP:0002323) | 2.00702087 |
| 71 | Nephrogenic diabetes insipidus (HP:0009806) | 1.99980941 |
| 72 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.99498300 |
| 73 | Rectal fistula (HP:0100590) | 1.99247455 |
| 74 | Rectovaginal fistula (HP:0000143) | 1.99247455 |
| 75 | Abnormal hemoglobin (HP:0011902) | 1.99153463 |
| 76 | Hyperglycinemia (HP:0002154) | 1.98464174 |
| 77 | Absent radius (HP:0003974) | 1.98375912 |
| 78 | Genital tract atresia (HP:0001827) | 1.98246754 |
| 79 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.98236603 |
| 80 | Acute necrotizing encephalopathy (HP:0006965) | 1.98113866 |
| 81 | Optic disc pallor (HP:0000543) | 1.95762913 |
| 82 | Pancreatic cysts (HP:0001737) | 1.95102003 |
| 83 | Myelodysplasia (HP:0002863) | 1.94858021 |
| 84 | Cupped ear (HP:0000378) | 1.94696512 |
| 85 | Acute myeloid leukemia (HP:0004808) | 1.94507858 |
| 86 | Intestinal atresia (HP:0011100) | 1.92640198 |
| 87 | True hermaphroditism (HP:0010459) | 1.92290024 |
| 88 | Mitochondrial inheritance (HP:0001427) | 1.91936602 |
| 89 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.90427219 |
| 90 | Short tibia (HP:0005736) | 1.89735798 |
| 91 | Ectopic kidney (HP:0000086) | 1.88406425 |
| 92 | Abolished electroretinogram (ERG) (HP:0000550) | 1.88213113 |
| 93 | Postaxial hand polydactyly (HP:0001162) | 1.87905667 |
| 94 | Male pseudohermaphroditism (HP:0000037) | 1.87786298 |
| 95 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.87717523 |
| 96 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.87148952 |
| 97 | Hypoplasia of the fovea (HP:0007750) | 1.86914060 |
| 98 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.86914060 |
| 99 | Aplastic anemia (HP:0001915) | 1.86540306 |
| 100 | Vaginal atresia (HP:0000148) | 1.85741849 |
| 101 | Abnormal lung lobation (HP:0002101) | 1.84849050 |
| 102 | Absent thumb (HP:0009777) | 1.84198753 |
| 103 | Macrocytic anemia (HP:0001972) | 1.84100332 |
| 104 | Rib fusion (HP:0000902) | 1.83428617 |
| 105 | Type I transferrin isoform profile (HP:0003642) | 1.83213959 |
| 106 | Absent septum pellucidum (HP:0001331) | 1.83089494 |
| 107 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.82477856 |
| 108 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.82477856 |
| 109 | Pancreatic fibrosis (HP:0100732) | 1.81707328 |
| 110 | Sensory axonal neuropathy (HP:0003390) | 1.81362135 |
| 111 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.79549742 |
| 112 | Methylmalonic aciduria (HP:0012120) | 1.79189613 |
| 113 | Adrenal hypoplasia (HP:0000835) | 1.79130925 |
| 114 | Intestinal fistula (HP:0100819) | 1.79018591 |
| 115 | Anophthalmia (HP:0000528) | 1.78310212 |
| 116 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.78169159 |
| 117 | Triphalangeal thumb (HP:0001199) | 1.76961369 |
| 118 | Pancytopenia (HP:0001876) | 1.76843655 |
| 119 | Abnormal drinking behavior (HP:0030082) | 1.76728043 |
| 120 | Polydipsia (HP:0001959) | 1.76728043 |
| 121 | Small intestinal stenosis (HP:0012848) | 1.76642640 |
| 122 | Duodenal stenosis (HP:0100867) | 1.76642640 |
| 123 | Exertional dyspnea (HP:0002875) | 1.75840788 |
| 124 | Anhidrosis (HP:0000970) | 1.75396451 |
| 125 | Bile duct proliferation (HP:0001408) | 1.75172914 |
| 126 | Abnormal biliary tract physiology (HP:0012439) | 1.75172914 |
| 127 | Aplasia involving forearm bones (HP:0009822) | 1.74785122 |
| 128 | Absent forearm bone (HP:0003953) | 1.74785122 |
| 129 | Pallor (HP:0000980) | 1.74772734 |
| 130 | Gaze-evoked nystagmus (HP:0000640) | 1.74651437 |
| 131 | Erythroderma (HP:0001019) | 1.74233151 |
| 132 | Growth hormone deficiency (HP:0000824) | 1.74047290 |
| 133 | Preaxial hand polydactyly (HP:0001177) | 1.74041586 |
| 134 | Agnosia (HP:0010524) | 1.74019977 |
| 135 | Abnormality of the fovea (HP:0000493) | 1.73911861 |
| 136 | Meckel diverticulum (HP:0002245) | 1.73329113 |
| 137 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.72925562 |
| 138 | Dry hair (HP:0011359) | 1.72889636 |
| 139 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.72316508 |
| 140 | Thyroiditis (HP:0100646) | 1.72277958 |
| 141 | Progressive macrocephaly (HP:0004481) | 1.72012956 |
| 142 | Abnormality of the septum pellucidum (HP:0007375) | 1.71957990 |
| 143 | Colon cancer (HP:0003003) | 1.71599655 |
| 144 | Enlarged kidneys (HP:0000105) | 1.71507483 |
| 145 | Embryonal renal neoplasm (HP:0011794) | 1.71324415 |
| 146 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.71213584 |
| 147 | Abnormality of cochlea (HP:0000375) | 1.71075430 |
| 148 | Abnormality of renal resorption (HP:0011038) | 1.70259361 |
| 149 | Respiratory failure (HP:0002878) | 1.70059482 |
| 150 | Progressive inability to walk (HP:0002505) | 1.69503474 |
| 151 | Optic nerve hypoplasia (HP:0000609) | 1.69400909 |
| 152 | Tubular atrophy (HP:0000092) | 1.69221905 |
| 153 | Abnormality of the incisor (HP:0000676) | 1.68704645 |
| 154 | Medial flaring of the eyebrow (HP:0010747) | 1.68253600 |
| 155 | Postaxial foot polydactyly (HP:0001830) | 1.68159864 |
| 156 | Sloping forehead (HP:0000340) | 1.68007084 |
| 157 | Tubulointerstitial nephritis (HP:0001970) | 1.66143418 |
| 158 | Clubbing of toes (HP:0100760) | 1.65850939 |
| 159 | Abnormal spermatogenesis (HP:0008669) | 1.65145109 |
| 160 | Metaphyseal dysplasia (HP:0100255) | 1.64752207 |
| 161 | Increased CSF lactate (HP:0002490) | 1.63253766 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PBK | 2.71134335 |
| 2 | MST4 | 2.61755813 |
| 3 | WNK3 | 2.61233282 |
| 4 | TNIK | 2.45320562 |
| 5 | STK39 | 2.43899124 |
| 6 | MKNK2 | 2.37852441 |
| 7 | PNCK | 2.18202230 |
| 8 | ZAK | 2.10983445 |
| 9 | CDC7 | 2.06410350 |
| 10 | TRIM28 | 2.04440505 |
| 11 | MKNK1 | 2.04103854 |
| 12 | SRPK1 | 2.04061434 |
| 13 | MAP3K4 | 1.99291769 |
| 14 | MAP4K2 | 1.89881465 |
| 15 | WEE1 | 1.87105054 |
| 16 | VRK2 | 1.82916155 |
| 17 | NUAK1 | 1.72382365 |
| 18 | MAP3K6 | 1.65356763 |
| 19 | PLK4 | 1.64780719 |
| 20 | NEK6 | 1.62359030 |
| 21 | ACVR1B | 1.60307490 |
| 22 | EIF2AK3 | 1.55919994 |
| 23 | MAPK13 | 1.53800403 |
| 24 | STK10 | 1.52867307 |
| 25 | BRD4 | 1.51769189 |
| 26 | PLK2 | 1.47366162 |
| 27 | TXK | 1.45548891 |
| 28 | VRK1 | 1.45099757 |
| 29 | OXSR1 | 1.43122137 |
| 30 | WNK4 | 1.35979142 |
| 31 | FRK | 1.34489797 |
| 32 | TLK1 | 1.34331265 |
| 33 | CDK3 | 1.34086744 |
| 34 | TTK | 1.30295490 |
| 35 | GRK7 | 1.29424616 |
| 36 | TEC | 1.28655699 |
| 37 | STK16 | 1.28523092 |
| 38 | CDK9 | 1.28460406 |
| 39 | PINK1 | 1.28213121 |
| 40 | DYRK2 | 1.26338570 |
| 41 | BMPR1B | 1.25799285 |
| 42 | PIK3CA | 1.21235241 |
| 43 | MUSK | 1.20915026 |
| 44 | IRAK4 | 1.20533364 |
| 45 | MAP2K7 | 1.18876758 |
| 46 | BCR | 1.18029676 |
| 47 | IRAK3 | 1.17150769 |
| 48 | YES1 | 1.16928869 |
| 49 | MAPK15 | 1.16564279 |
| 50 | FGFR2 | 1.14973940 |
| 51 | BRSK2 | 1.13720433 |
| 52 | PLK3 | 1.10510290 |
| 53 | ADRBK2 | 1.09808843 |
| 54 | MAPKAPK5 | 1.06432808 |
| 55 | EIF2AK2 | 1.04871168 |
| 56 | RPS6KA5 | 1.02754913 |
| 57 | MAP3K14 | 1.01640201 |
| 58 | AURKB | 1.00709982 |
| 59 | CASK | 0.99653722 |
| 60 | DYRK3 | 0.98866682 |
| 61 | TRPM7 | 0.97813913 |
| 62 | INSRR | 0.95390884 |
| 63 | ATR | 0.95138114 |
| 64 | CHEK2 | 0.95046170 |
| 65 | OBSCN | 0.93790422 |
| 66 | TAOK3 | 0.92863158 |
| 67 | ATM | 0.92349703 |
| 68 | MELK | 0.91916160 |
| 69 | PAK3 | 0.91389055 |
| 70 | STK4 | 0.90795367 |
| 71 | PASK | 0.90747466 |
| 72 | PKN1 | 0.90595139 |
| 73 | ITK | 0.90200431 |
| 74 | CDK19 | 0.87961700 |
| 75 | NEK9 | 0.85805599 |
| 76 | MAP2K3 | 0.82207662 |
| 77 | NME1 | 0.81924055 |
| 78 | CSNK1G3 | 0.81354046 |
| 79 | CLK1 | 0.79205481 |
| 80 | STK38L | 0.79005089 |
| 81 | BUB1 | 0.78768282 |
| 82 | AKT3 | 0.78761917 |
| 83 | PLK1 | 0.78244458 |
| 84 | CSNK1A1L | 0.77853935 |
| 85 | IRAK1 | 0.77052017 |
| 86 | TSSK6 | 0.76706182 |
| 87 | PRKCG | 0.74777923 |
| 88 | LCK | 0.74714317 |
| 89 | CSNK1G1 | 0.74459218 |
| 90 | NLK | 0.72448213 |
| 91 | NEK2 | 0.72196747 |
| 92 | EPHA4 | 0.70425625 |
| 93 | MET | 0.69765384 |
| 94 | CDK8 | 0.67607830 |
| 95 | NTRK2 | 0.67588500 |
| 96 | RPS6KB2 | 0.67234656 |
| 97 | WNK1 | 0.65127747 |
| 98 | CDK6 | 0.64553562 |
| 99 | NEK1 | 0.64287253 |
| 100 | RPS6KA4 | 0.63549631 |
| 101 | TGFBR1 | 0.63414900 |
| 102 | BTK | 0.60670499 |
| 103 | NTRK3 | 0.59431272 |
| 104 | CSNK1G2 | 0.58765938 |
| 105 | PIK3CG | 0.57877365 |
| 106 | CDK7 | 0.57724959 |
| 107 | IKBKB | 0.56537110 |
| 108 | CSNK1E | 0.56344835 |
| 109 | IKBKE | 0.56157327 |
| 110 | CSNK2A2 | 0.55865985 |
| 111 | TAF1 | 0.55624188 |
| 112 | PRKCQ | 0.55397390 |
| 113 | CSNK2A1 | 0.54742948 |
| 114 | MAP2K4 | 0.53316518 |
| 115 | ADRBK1 | 0.52414606 |
| 116 | LYN | 0.52013385 |
| 117 | CSNK1D | 0.51728370 |
| 118 | ERBB3 | 0.51489915 |
| 119 | PRKAA2 | 0.51449391 |
| 120 | MARK1 | 0.51295515 |
| 121 | IRAK2 | 0.51266636 |
| 122 | BCKDK | 0.49820453 |
| 123 | CHEK1 | 0.48589332 |
| 124 | PRKCE | 0.48402180 |
| 125 | KIT | 0.47843163 |
| 126 | TGFBR2 | 0.47577669 |
| 127 | PIM1 | 0.47309635 |
| 128 | CCNB1 | 0.47015304 |
| 129 | FGR | 0.46752877 |
| 130 | CDK12 | 0.46527893 |
| 131 | GRK1 | 0.45777961 |
| 132 | SGK2 | 0.45366043 |
| 133 | STK3 | 0.44586285 |
| 134 | CDK1 | 0.44550736 |
| 135 | MAP4K1 | 0.44533718 |
| 136 | AURKA | 0.44392344 |
| 137 | PRKACB | 0.43275627 |
| 138 | PRKG1 | 0.43254075 |
| 139 | CAMK1D | 0.43155775 |
| 140 | TNK2 | 0.42310662 |
| 141 | PRKACA | 0.41467941 |
| 142 | DYRK1A | 0.41172585 |
| 143 | CAMK2A | 0.40584592 |
| 144 | MINK1 | 0.38802594 |
| 145 | CAMK1 | 0.38468389 |
| 146 | SGK1 | 0.37583816 |
| 147 | MAP3K12 | 0.36799921 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.62697336 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.43843280 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.27799911 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 2.85113834 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 2.83519945 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.53774965 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.48564869 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.45377831 |
| 9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.21157198 |
| 10 | DNA replication_Homo sapiens_hsa03030 | 2.19946090 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.18197878 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 2.17155712 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.12433014 |
| 14 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.90358880 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.81057580 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.77349117 |
| 17 | Cell cycle_Homo sapiens_hsa04110 | 1.71347753 |
| 18 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.70441602 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.69842799 |
| 20 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.66107429 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.64325466 |
| 22 | Proteasome_Homo sapiens_hsa03050 | 1.58909867 |
| 23 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.54482361 |
| 24 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.54465031 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.53393216 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.45767134 |
| 27 | Base excision repair_Homo sapiens_hsa03410 | 1.45074830 |
| 28 | Parkinsons disease_Homo sapiens_hsa05012 | 1.41111655 |
| 29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.34565842 |
| 30 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.31366857 |
| 31 | Nicotine addiction_Homo sapiens_hsa05033 | 1.27586490 |
| 32 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.20646018 |
| 33 | Huntingtons disease_Homo sapiens_hsa05016 | 1.16309450 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.15567702 |
| 35 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.14630610 |
| 36 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.13508666 |
| 37 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.13384842 |
| 38 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.11355357 |
| 39 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.10945978 |
| 40 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.09443475 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.08454237 |
| 42 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.05372905 |
| 43 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.04713848 |
| 44 | Alzheimers disease_Homo sapiens_hsa05010 | 1.03515458 |
| 45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.00187135 |
| 46 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.98171525 |
| 47 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.97982531 |
| 48 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.95422971 |
| 49 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.94658646 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.94189189 |
| 51 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.94031190 |
| 52 | Allograft rejection_Homo sapiens_hsa05330 | 0.93011070 |
| 53 | Purine metabolism_Homo sapiens_hsa00230 | 0.92857961 |
| 54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.90727988 |
| 55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.88154972 |
| 56 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87113212 |
| 57 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.85863319 |
| 58 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.85471755 |
| 59 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.84808908 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83404265 |
| 61 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.82902271 |
| 62 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.82119066 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.81616034 |
| 64 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.81350583 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.81325448 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.80318543 |
| 67 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.79398356 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.77753194 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76427297 |
| 70 | Taste transduction_Homo sapiens_hsa04742 | 0.76202595 |
| 71 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.74493629 |
| 72 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.74453467 |
| 73 | Malaria_Homo sapiens_hsa05144 | 0.74181846 |
| 74 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70722643 |
| 75 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70229644 |
| 76 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.67459877 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.67380273 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.66490328 |
| 79 | Measles_Homo sapiens_hsa05162 | 0.65764868 |
| 80 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.65424942 |
| 81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65155790 |
| 82 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.64709158 |
| 83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.64589083 |
| 84 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.64112849 |
| 85 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.63504975 |
| 86 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63007611 |
| 87 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.62210377 |
| 88 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.60917055 |
| 89 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59516966 |
| 90 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.59257431 |
| 91 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.58430514 |
| 92 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.58129281 |
| 93 | Asthma_Homo sapiens_hsa05310 | 0.58101802 |
| 94 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.56111576 |
| 95 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.55147952 |
| 96 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54376396 |
| 97 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.53955634 |
| 98 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52717462 |
| 99 | Phototransduction_Homo sapiens_hsa04744 | 0.51976499 |
| 100 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51674257 |
| 101 | Morphine addiction_Homo sapiens_hsa05032 | 0.51266625 |
| 102 | GABAergic synapse_Homo sapiens_hsa04727 | 0.49899511 |
| 103 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.49450606 |
| 104 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.49040746 |
| 105 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.48464496 |
| 106 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.48271067 |
| 107 | ABC transporters_Homo sapiens_hsa02010 | 0.47615066 |
| 108 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45927634 |
| 109 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45072754 |
| 110 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44525016 |
| 111 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.42729811 |
| 112 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.39767839 |
| 113 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.37549120 |
| 114 | Alcoholism_Homo sapiens_hsa05034 | 0.36078227 |
| 115 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35501118 |
| 116 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.35477228 |
| 117 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.35436884 |
| 118 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.34826808 |
| 119 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.34057295 |
| 120 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.33994196 |
| 121 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.32409702 |
| 122 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.31942767 |
| 123 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.31825396 |
| 124 | Peroxisome_Homo sapiens_hsa04146 | 0.31805582 |
| 125 | Circadian entrainment_Homo sapiens_hsa04713 | 0.31624098 |
| 126 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.31294765 |
| 127 | Circadian rhythm_Homo sapiens_hsa04710 | 0.31246178 |
| 128 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30199805 |
| 129 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.26793052 |
| 130 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.25634495 |
| 131 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.25117347 |
| 132 | Insulin secretion_Homo sapiens_hsa04911 | 0.24151954 |
| 133 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.23764313 |
| 134 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.23277791 |
| 135 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.21137880 |
| 136 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.18589528 |

