CWF19L2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.27559457
2energy coupled proton transport, down electrochemical gradient (GO:0015985)4.43000132
3ATP synthesis coupled proton transport (GO:0015986)4.43000132
4axon ensheathment in central nervous system (GO:0032291)4.05936243
5central nervous system myelination (GO:0022010)4.05936243
6protein complex biogenesis (GO:0070271)3.94526321
7respiratory electron transport chain (GO:0022904)3.83606595
8chaperone-mediated protein transport (GO:0072321)3.83375275
9ribosomal small subunit assembly (GO:0000028)3.79581079
10ribosomal small subunit biogenesis (GO:0042274)3.78907489
11electron transport chain (GO:0022900)3.77635429
12mitochondrial respiratory chain complex I assembly (GO:0032981)3.77291146
13NADH dehydrogenase complex assembly (GO:0010257)3.77291146
14mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.77291146
15CENP-A containing nucleosome assembly (GO:0034080)3.74728114
16kinetochore organization (GO:0051383)3.69216359
17mitochondrial respiratory chain complex assembly (GO:0033108)3.67225042
18centriole replication (GO:0007099)3.66999084
19epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.66789881
20DNA ligation (GO:0006266)3.66497852
21negative regulation of DNA-dependent DNA replication (GO:2000104)3.63142489
22chromatin remodeling at centromere (GO:0031055)3.62412120
23protein-cofactor linkage (GO:0018065)3.59325833
24meiotic chromosome segregation (GO:0045132)3.36882017
25intraciliary transport (GO:0042073)3.28397532
26respiratory chain complex IV assembly (GO:0008535)3.27194975
27neural tube formation (GO:0001841)3.22542193
28positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.21995721
29positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.21995721
30positive regulation of mitotic sister chromatid separation (GO:1901970)3.21995721
31DNA damage response, detection of DNA damage (GO:0042769)3.18930375
32regulation of helicase activity (GO:0051095)3.18072510
33microtubule polymerization or depolymerization (GO:0031109)3.16854149
34inner mitochondrial membrane organization (GO:0007007)3.13000654
35cytochrome complex assembly (GO:0017004)3.11110889
36attachment of spindle microtubules to kinetochore (GO:0008608)3.10794640
37positive regulation of histone H3-K4 methylation (GO:0051571)3.10548659
38RNA-dependent DNA replication (GO:0006278)3.09962624
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.07484807
40tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.07269406
41RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.07269406
42positive regulation of chromosome segregation (GO:0051984)3.05096334
43kinetochore assembly (GO:0051382)3.02901901
44telomere maintenance via telomerase (GO:0007004)3.01736283
45DNA replication-independent nucleosome organization (GO:0034724)2.97832905
46DNA replication-independent nucleosome assembly (GO:0006336)2.97832905
47histone exchange (GO:0043486)2.96331229
48microtubule depolymerization (GO:0007019)2.91987441
49viral transcription (GO:0019083)2.91003553
50DNA deamination (GO:0045006)2.89811482
51epithelial cilium movement (GO:0003351)2.89710508
52translational termination (GO:0006415)2.89063778
53cotranslational protein targeting to membrane (GO:0006613)2.87848288
54maturation of SSU-rRNA (GO:0030490)2.86192990
55regulation of DNA endoreduplication (GO:0032875)2.86174315
56regulation of sister chromatid cohesion (GO:0007063)2.84969993
57translational elongation (GO:0006414)2.84345485
58histone H3-K4 trimethylation (GO:0080182)2.83845789
59protein neddylation (GO:0045116)2.82666853
60fatty acid elongation (GO:0030497)2.81887868
61DNA double-strand break processing (GO:0000729)2.80958843
62nuclear pore complex assembly (GO:0051292)2.80572423
63mitotic sister chromatid cohesion (GO:0007064)2.79964252
64metaphase plate congression (GO:0051310)2.78995093
65regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.77674509
66termination of RNA polymerase III transcription (GO:0006386)2.77223456
67transcription elongation from RNA polymerase III promoter (GO:0006385)2.77223456
68protein targeting to ER (GO:0045047)2.76957746
69proteasome assembly (GO:0043248)2.76076491
70SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.75342852
71intracellular protein transmembrane import (GO:0044743)2.72448774
72centriole assembly (GO:0098534)2.72322713
73protein localization to cilium (GO:0061512)2.71774005
74synapsis (GO:0007129)2.71266449
75kidney morphogenesis (GO:0060993)2.70361879
76positive regulation of cellular amine metabolic process (GO:0033240)2.69054990
77translational initiation (GO:0006413)2.68986873
78GPI anchor biosynthetic process (GO:0006506)2.68014194
79cellular protein complex disassembly (GO:0043624)2.67766796
80ribosomal large subunit biogenesis (GO:0042273)2.66650268
81positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.66375460
82regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.66375460
83maturation of 5.8S rRNA (GO:0000460)2.66357750
84establishment of protein localization to endoplasmic reticulum (GO:0072599)2.66263268
85behavioral response to nicotine (GO:0035095)2.66223896
86regulation of nuclear cell cycle DNA replication (GO:0033262)2.65809937
87protein localization to endoplasmic reticulum (GO:0070972)2.65668309
88regulation of meiosis I (GO:0060631)2.65603422
89response to pheromone (GO:0019236)2.65491885
90histone H2B ubiquitination (GO:0033523)2.64144387
91nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.61347202
92piRNA metabolic process (GO:0034587)2.61210278
93cullin deneddylation (GO:0010388)2.58800467
94pore complex assembly (GO:0046931)2.57855696
95DNA unwinding involved in DNA replication (GO:0006268)2.57568307
96single strand break repair (GO:0000012)2.56838792
97viral life cycle (GO:0019058)2.56549339
98intra-S DNA damage checkpoint (GO:0031573)2.56473131
99reciprocal meiotic recombination (GO:0007131)2.54940523
100reciprocal DNA recombination (GO:0035825)2.54940523
101water-soluble vitamin biosynthetic process (GO:0042364)2.54908035
102negative regulation of transcription regulatory region DNA binding (GO:2000678)2.54664798
103protein K6-linked ubiquitination (GO:0085020)2.54653837
104regulation of mitochondrial translation (GO:0070129)2.54565724
105preassembly of GPI anchor in ER membrane (GO:0016254)2.53719330
106definitive hemopoiesis (GO:0060216)2.53494739
107establishment of integrated proviral latency (GO:0075713)2.53441718
108nuclear pore organization (GO:0006999)2.52178714
109double-strand break repair via nonhomologous end joining (GO:0006303)2.51926925
110non-recombinational repair (GO:0000726)2.51926925
111mitotic recombination (GO:0006312)2.50567987
112rRNA modification (GO:0000154)2.50357117
113transcription elongation from RNA polymerase I promoter (GO:0006362)2.49686033
114DNA catabolic process, exonucleolytic (GO:0000738)2.49345270
115translation (GO:0006412)2.48835441
116somite development (GO:0061053)2.47161337
117otic vesicle formation (GO:0030916)2.46836911
118mismatch repair (GO:0006298)2.46363177
119negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.46028075
120negative regulation of translation, ncRNA-mediated (GO:0040033)2.46028075
121regulation of translation, ncRNA-mediated (GO:0045974)2.46028075
122hydrogen ion transmembrane transport (GO:1902600)2.45828913
123GPI anchor metabolic process (GO:0006505)2.45654891
124regulation of histone H3-K9 methylation (GO:0051570)2.45025423
125ncRNA catabolic process (GO:0034661)2.44339976
126replication fork processing (GO:0031297)2.44099652
127retinal cone cell development (GO:0046549)2.43388555
128RNA capping (GO:0036260)2.41992026
1297-methylguanosine RNA capping (GO:0009452)2.41992026
130regulation of cilium movement (GO:0003352)2.40894630
131detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.40607936
132nonmotile primary cilium assembly (GO:0035058)2.40349860
133DNA replication checkpoint (GO:0000076)2.40197166
134resolution of meiotic recombination intermediates (GO:0000712)2.40096153
135mitotic metaphase plate congression (GO:0007080)2.39954235
136nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.38896237
137mitotic G2/M transition checkpoint (GO:0044818)2.38470016
138regulation of mitotic spindle checkpoint (GO:1903504)2.38382291
139regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.38382291
140peptidyl-lysine trimethylation (GO:0018023)2.38055789
141DNA topological change (GO:0006265)2.38051039
142mitotic chromosome condensation (GO:0007076)2.37785761
143maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.37601913
144microtubule anchoring (GO:0034453)2.37034180
145regulation of mitotic spindle organization (GO:0060236)2.36485961
146telomere maintenance via recombination (GO:0000722)2.35406185
147positive regulation of histone methylation (GO:0031062)2.34691761
148establishment of viral latency (GO:0019043)2.34638832
149DNA replication initiation (GO:0006270)2.34360349
150recombinational repair (GO:0000725)2.33254193
151double-strand break repair via homologous recombination (GO:0000724)2.32971224
152establishment of chromosome localization (GO:0051303)2.32187615
153exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.31676768
154telomere organization (GO:0032200)2.30799372
155histone mRNA metabolic process (GO:0008334)2.30243460
156sister chromatid cohesion (GO:0007062)2.29219887
157regulation of spindle organization (GO:0090224)2.29137092
158mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.28687913
1597-methylguanosine mRNA capping (GO:0006370)2.27730652
160viral mRNA export from host cell nucleus (GO:0046784)2.27657181
161telomere maintenance (GO:0000723)2.27531513

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.65641419
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.85593821
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.15112323
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.13091674
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.09560154
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.84270972
7ZNF274_21170338_ChIP-Seq_K562_Hela2.82824574
8EZH2_22144423_ChIP-Seq_EOC_Human2.77373082
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.73647041
10VDR_22108803_ChIP-Seq_LS180_Human2.60135916
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.54165060
12* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.45950355
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.37323785
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.37286740
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.33765987
16FUS_26573619_Chip-Seq_HEK293_Human2.30307413
17ELK1_19687146_ChIP-ChIP_HELA_Human2.26974514
18FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.26346389
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.19060885
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.15730989
21PCGF2_27294783_Chip-Seq_ESCs_Mouse2.11185162
22TAF15_26573619_Chip-Seq_HEK293_Human2.10551572
23BP1_19119308_ChIP-ChIP_Hs578T_Human2.06503991
24EWS_26573619_Chip-Seq_HEK293_Human2.04679244
25FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.03517094
26IRF1_19129219_ChIP-ChIP_H3396_Human1.93097357
27CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.87190810
28RBPJ_22232070_ChIP-Seq_NCS_Mouse1.82690810
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.82012139
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.77757711
31KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.73677004
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.70503731
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69920171
34IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.69633426
35PCGF2_27294783_Chip-Seq_NPCs_Mouse1.66932302
36* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.61628691
37MYC_18555785_ChIP-Seq_MESCs_Mouse1.60535835
38CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.59711101
39IGF1R_20145208_ChIP-Seq_DFB_Human1.59275542
40* VDR_23849224_ChIP-Seq_CD4+_Human1.58731525
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52289731
42MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.47241514
43* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46531338
44CREB1_15753290_ChIP-ChIP_HEK293T_Human1.45526426
45KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.45304537
46KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.45304537
47KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.45304537
48EZH2_27294783_Chip-Seq_NPCs_Mouse1.43929934
49* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42352187
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.42191562
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.41919285
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.41863897
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.41479020
54NFE2_27457419_Chip-Seq_LIVER_Mouse1.40689491
55SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.40671070
56TP53_22573176_ChIP-Seq_HFKS_Human1.36669400
57* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36604982
58* CBP_20019798_ChIP-Seq_JUKART_Human1.36604982
59GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.35697914
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.34209923
61EGR1_23403033_ChIP-Seq_LIVER_Mouse1.32989773
62* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32822174
63POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.30324606
64TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30324606
65FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29903442
66FOXP3_21729870_ChIP-Seq_TREG_Human1.26632230
67EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26411971
68YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25708437
69IRF8_21731497_ChIP-ChIP_J774_Mouse1.24556222
70TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23516465
71SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.23322838
72RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.22882900
73* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.22377833
74BCAT_22108803_ChIP-Seq_LS180_Human1.21703289
75SMAD3_21741376_ChIP-Seq_EPCs_Human1.21381101
76SRF_21415370_ChIP-Seq_HL-1_Mouse1.20957731
77SUZ12_18555785_Chip-Seq_ESCs_Mouse1.19654050
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.19413341
79BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19194059
80E2F1_18555785_Chip-Seq_ESCs_Mouse1.18876234
81P300_18555785_Chip-Seq_ESCs_Mouse1.18642811
82ER_23166858_ChIP-Seq_MCF-7_Human1.18642146
83OCT4_18555785_Chip-Seq_ESCs_Mouse1.18160688
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.17619801
85SMAD4_21799915_ChIP-Seq_A2780_Human1.17095450
86NELFA_20434984_ChIP-Seq_ESCs_Mouse1.16630899
87TP63_19390658_ChIP-ChIP_HaCaT_Human1.16006405
88SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.15803682
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15789981
90ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.15629263
91P300_19829295_ChIP-Seq_ESCs_Human1.15072507
92MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14373489
93STAT3_18555785_Chip-Seq_ESCs_Mouse1.14322294
94TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13791223
95EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13725014
96TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13542837
97SOX2_16153702_ChIP-ChIP_HESCs_Human1.12208594
98EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.12073701
99TCF4_23295773_ChIP-Seq_U87_Human1.10095026
100* AR_25329375_ChIP-Seq_VCAP_Human1.09590552
101SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.09333511
102RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09325429
103CMYC_18555785_Chip-Seq_ESCs_Mouse1.09126595
104CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08996344
105PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08690627
106RNF2_27304074_Chip-Seq_NSC_Mouse1.08648644
107HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.07729807
108RUNX1_27457419_Chip-Seq_LIVER_Mouse1.07447404
109* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.07024283
110NANOG_19829295_ChIP-Seq_ESCs_Human1.06708755
111SOX2_19829295_ChIP-Seq_ESCs_Human1.06708755
112OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05843452
113ERG_20887958_ChIP-Seq_HPC-7_Mouse1.05204359
114P53_22387025_ChIP-Seq_ESCs_Mouse1.05126452
115TCF4_22108803_ChIP-Seq_LS180_Human1.04564075
116GBX2_23144817_ChIP-Seq_PC3_Human1.04089411
117STAT3_23295773_ChIP-Seq_U87_Human1.03996534
118PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02643733
119* TAL1_26923725_Chip-Seq_HPCs_Mouse1.02602474
120RUNX2_22187159_ChIP-Seq_PCA_Human1.02177663
121CRX_20693478_ChIP-Seq_RETINA_Mouse1.01953172
122MYC_18940864_ChIP-ChIP_HL60_Human1.01460802
123STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.00849937
124FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00389940
125FOXA1_25329375_ChIP-Seq_VCAP_Human1.00050035
126FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00050035
127NMYC_18555785_Chip-Seq_ESCs_Mouse1.00030225
128SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.99626308
129KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99267123
130TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.98059959
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97945671
132SOX2_18555785_Chip-Seq_ESCs_Mouse0.97756379
133ZFX_18555785_Chip-Seq_ESCs_Mouse0.97583327
134E2F1_21310950_ChIP-Seq_MCF-7_Human0.97074338
135KLF4_18555785_Chip-Seq_ESCs_Mouse0.96785891
136SMAD1_18555785_Chip-Seq_ESCs_Mouse0.95875374
137* ETS1_20019798_ChIP-Seq_JURKAT_Human0.95206934
138CBX2_27304074_Chip-Seq_ESCs_Mouse0.94801310
139NOTCH1_21737748_ChIP-Seq_TLL_Human0.94548499
140PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92307758
141TTF2_22483619_ChIP-Seq_HELA_Human0.91371853

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.86044151
2MP0003136_yellow_coat_color4.29415894
3MP0002009_preneoplasia4.17983041
4MP0003950_abnormal_plasma_membrane3.47119047
5MP0005409_darkened_coat_color3.06779068
6MP0008877_abnormal_DNA_methylation3.02366661
7MP0009379_abnormal_foot_pigmentation2.96501321
8MP0009697_abnormal_copulation2.67800007
9MP0010094_abnormal_chromosome_stability2.53635452
10MP0008058_abnormal_DNA_repair2.28775161
11MP0000569_abnormal_digit_pigmentation2.23758282
12MP0002102_abnormal_ear_morphology2.17143674
13MP0002166_altered_tumor_susceptibility2.12760477
14MP0003077_abnormal_cell_cycle2.03628084
15MP0008789_abnormal_olfactory_epithelium2.03219056
16MP0003787_abnormal_imprinting2.02939313
17MP0004381_abnormal_hair_follicle2.01835135
18MP0001986_abnormal_taste_sensitivity2.00258925
19MP0001984_abnormal_olfaction1.99083873
20MP0003693_abnormal_embryo_hatching1.97535799
21MP0005171_absent_coat_pigmentation1.94202705
22MP0004147_increased_porphyrin_level1.91817107
23MP0002837_dystrophic_cardiac_calcinosis1.83759833
24MP0004885_abnormal_endolymph1.80704140
25MP0004957_abnormal_blastocyst_morpholog1.74458621
26MP0003880_abnormal_central_pattern1.74163270
27MP0002006_tumorigenesis1.73733683
28MP0003724_increased_susceptibility_to1.73298165
29MP0005551_abnormal_eye_electrophysiolog1.68023236
30MP0002277_abnormal_respiratory_mucosa1.66896577
31MP0001293_anophthalmia1.66766195
32MP0002638_abnormal_pupillary_reflex1.63540650
33MP0005394_taste/olfaction_phenotype1.63322117
34MP0005499_abnormal_olfactory_system1.63322117
35MP0003111_abnormal_nucleus_morphology1.60800747
36MP0005174_abnormal_tail_pigmentation1.58858401
37MP0003718_maternal_effect1.58677621
38MP0000631_abnormal_neuroendocrine_gland1.58127524
39MP0002396_abnormal_hematopoietic_system1.55263635
40MP0002163_abnormal_gland_morphology1.54618518
41MP0001485_abnormal_pinna_reflex1.53470091
42MP0003121_genomic_imprinting1.51783669
43MP0001188_hyperpigmentation1.51444195
44MP0005379_endocrine/exocrine_gland_phen1.50844914
45MP0004142_abnormal_muscle_tone1.50224128
46MP0005408_hypopigmentation1.47909500
47MP0002095_abnormal_skin_pigmentation1.45079905
48MP0002736_abnormal_nociception_after1.40853531
49MP0000920_abnormal_myelination1.38113950
50MP0006276_abnormal_autonomic_nervous1.34844684
51MP0000383_abnormal_hair_follicle1.34037414
52MP0005646_abnormal_pituitary_gland1.31779985
53MP0006072_abnormal_retinal_apoptosis1.30783206
54MP0005075_abnormal_melanosome_morpholog1.28597064
55MP0000372_irregular_coat_pigmentation1.26688881
56MP0002160_abnormal_reproductive_system1.24874804
57MP0003937_abnormal_limbs/digits/tail_de1.24307384
58MP0008932_abnormal_embryonic_tissue1.23926395
59MP0005671_abnormal_response_to1.23899735
60MP0002938_white_spotting1.22996802
61MP0008995_early_reproductive_senescence1.20899181
62MP0003195_calcinosis1.20798773
63MP0002272_abnormal_nervous_system1.19809980
64MP0003011_delayed_dark_adaptation1.19559609
65MP0002928_abnormal_bile_duct1.18329877
66MP0001486_abnormal_startle_reflex1.18023023
67MP0003186_abnormal_redox_activity1.17453719
68MP0003122_maternal_imprinting1.17257312
69MP0002132_abnormal_respiratory_system1.16586006
70MP0000778_abnormal_nervous_system1.16575771
71MP0001851_eye_inflammation1.15916935
72MP0003690_abnormal_glial_cell1.15758092
73MP0005377_hearing/vestibular/ear_phenot1.15654410
74MP0003878_abnormal_ear_physiology1.15654410
75MP0003786_premature_aging1.15541888
76MP0001324_abnormal_eye_pigmentation1.14596008
77MP0002234_abnormal_pharynx_morphology1.13956329
78MP0002653_abnormal_ependyma_morphology1.13021709
79MP0001968_abnormal_touch/_nociception1.12899870
80MP0001529_abnormal_vocalization1.11643731
81MP0009046_muscle_twitch1.08960926
82MP0001835_abnormal_antigen_presentation1.07753021
83MP0009745_abnormal_behavioral_response1.07034471
84MP0000427_abnormal_hair_cycle1.06447672
85MP0003763_abnormal_thymus_physiology1.05455629
86MP0010678_abnormal_skin_adnexa1.05058221
87MP0004133_heterotaxia1.04106798
88MP0003938_abnormal_ear_development1.03410834
89MP0003941_abnormal_skin_development1.02290609
90MP0000566_synostosis1.01008345
91MP0005195_abnormal_posterior_eye1.00689122
92MP0003567_abnormal_fetal_cardiomyocyte1.00521444
93MP0006036_abnormal_mitochondrial_physio0.98871261
94MP0003806_abnormal_nucleotide_metabolis0.98506099
95MP0001800_abnormal_humoral_immune0.96590328
96MP0002752_abnormal_somatic_nervous0.95777402
97MP0006035_abnormal_mitochondrial_morpho0.93480891
98MP0001919_abnormal_reproductive_system0.92961183
99MP0001346_abnormal_lacrimal_gland0.92924603
100MP0001186_pigmentation_phenotype0.92687560
101MP0005253_abnormal_eye_physiology0.92243129
102MP0005391_vision/eye_phenotype0.92190124
103MP0002751_abnormal_autonomic_nervous0.91479349
104MP0001661_extended_life_span0.91108915
105MP0002148_abnormal_hypersensitivity_rea0.90773717
106MP0010307_abnormal_tumor_latency0.90615467
107MP0001286_abnormal_eye_development0.90605032
108MP0008007_abnormal_cellular_replicative0.90040302
109MP0002723_abnormal_immune_serum0.88951925
110MP0000465_gastrointestinal_hemorrhage0.87727651
111MP0003119_abnormal_digestive_system0.87268886
112MP0004264_abnormal_extraembryonic_tissu0.85529610
113MP0002233_abnormal_nose_morphology0.84494656
114MP0003698_abnormal_male_reproductive0.84404112
115MP0009785_altered_susceptibility_to0.84391386
116MP0004742_abnormal_vestibular_system0.84384637
117MP0000015_abnormal_ear_pigmentation0.84337068
118MP0005084_abnormal_gallbladder_morpholo0.83150402
119MP0001929_abnormal_gametogenesis0.81539784
120MP0002075_abnormal_coat/hair_pigmentati0.80990165
121MP0002067_abnormal_sensory_capabilities0.80575866
122MP0005000_abnormal_immune_tolerance0.80514847
123MP0004924_abnormal_behavior0.78817720
124MP0005386_behavior/neurological_phenoty0.78817720
125MP0002210_abnormal_sex_determination0.78541214
126MP0001905_abnormal_dopamine_level0.77361907
127MP0002557_abnormal_social/conspecific_i0.77075947
128MP0002420_abnormal_adaptive_immunity0.76068860
129MP0005389_reproductive_system_phenotype0.74714311
130MP0004145_abnormal_muscle_electrophysio0.74611618
131MP0000026_abnormal_inner_ear0.74474251
132MP0002090_abnormal_vision0.74429478
133MP0000647_abnormal_sebaceous_gland0.74413917
134MP0003828_pulmonary_edema0.74064249
135MP0000462_abnormal_digestive_system0.73573136
136MP0001764_abnormal_homeostasis0.72672685
137MP0001819_abnormal_immune_cell0.72416190
138MP0000689_abnormal_spleen_morphology0.72080031
139MP0002419_abnormal_innate_immunity0.71618127
140MP0008872_abnormal_physiological_respon0.70313369
141MP0002452_abnormal_antigen_presenting0.70185955
142MP0006292_abnormal_olfactory_placode0.69633043
143MP0005025_abnormal_response_to0.67227366
144MP0002722_abnormal_immune_system0.65874203
145MP0002398_abnormal_bone_marrow0.64090623
146MP0000432_abnormal_head_morphology0.63526710
147MP0005367_renal/urinary_system_phenotyp0.63258120
148MP0000516_abnormal_urinary_system0.63258120
149MP0001145_abnormal_male_reproductive0.63115212
150MP0000716_abnormal_immune_system0.61823047
151MP0002098_abnormal_vibrissa_morphology0.61702175
152MP0003890_abnormal_embryonic-extraembry0.60955309
153MP0002405_respiratory_system_inflammati0.60866137
154MP0000653_abnormal_sex_gland0.60122970
155MP0000762_abnormal_tongue_morphology0.59429108
156MP0000703_abnormal_thymus_morphology0.57569095

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.94759920
2Nephronophthisis (HP:0000090)3.41389066
3Parakeratosis (HP:0001036)3.28368121
4Acute encephalopathy (HP:0006846)3.27640039
5Volvulus (HP:0002580)3.19332637
6Abnormal mitochondria in muscle tissue (HP:0008316)3.18234231
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.16652573
8Abnormality of the renal medulla (HP:0100957)3.01396684
9Abnormality of the renal cortex (HP:0011035)2.97393607
10Fair hair (HP:0002286)2.91587289
11Increased hepatocellular lipid droplets (HP:0006565)2.88632535
12Asplenia (HP:0001746)2.87318936
13Supernumerary spleens (HP:0009799)2.84711402
14Abnormal ciliary motility (HP:0012262)2.84463153
15Chronic hepatic failure (HP:0100626)2.81537122
16Reticulocytopenia (HP:0001896)2.81115976
173-Methylglutaconic aciduria (HP:0003535)2.72741286
18Abnormality of chromosome stability (HP:0003220)2.70113018
19Septo-optic dysplasia (HP:0100842)2.69113287
20Hepatocellular necrosis (HP:0001404)2.64372312
21Duplicated collecting system (HP:0000081)2.63624051
22Patchy hypopigmentation of hair (HP:0011365)2.62103927
23Renal Fanconi syndrome (HP:0001994)2.59009126
24Abnormality of the renal collecting system (HP:0004742)2.55004739
25Birth length less than 3rd percentile (HP:0003561)2.51446798
26Lipid accumulation in hepatocytes (HP:0006561)2.51408344
27Congenital, generalized hypertrichosis (HP:0004540)2.51025633
28Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.48749622
29Methylmalonic acidemia (HP:0002912)2.46950328
30Abnormality of the labia minora (HP:0012880)2.43696106
31Aplasia/Hypoplasia of the spleen (HP:0010451)2.43577602
32Abnormal respiratory motile cilium physiology (HP:0012261)2.42731470
33White forelock (HP:0002211)2.42508928
34Hepatic necrosis (HP:0002605)2.38065875
35Generalized hypopigmentation of hair (HP:0011358)2.37033823
36Degeneration of the lateral corticospinal tracts (HP:0002314)2.36602537
37Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.36602537
38Abnormality of cells of the erythroid lineage (HP:0012130)2.36104160
39Cerebral edema (HP:0002181)2.36075608
40Autoamputation (HP:0001218)2.34824069
41Lip pit (HP:0100267)2.32043270
42Absent/shortened dynein arms (HP:0200106)2.31186962
43Dynein arm defect of respiratory motile cilia (HP:0012255)2.31186962
44Hypochromic microcytic anemia (HP:0004840)2.29509844
45Abnormality of midbrain morphology (HP:0002418)2.26778162
46Molar tooth sign on MRI (HP:0002419)2.26778162
47Abnormality of the preputium (HP:0100587)2.26460092
48Oligodactyly (hands) (HP:0001180)2.26072903
49Abnormality of the axillary hair (HP:0100134)2.25740826
50Abnormality of secondary sexual hair (HP:0009888)2.25740826
51Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.23156409
5211 pairs of ribs (HP:0000878)2.22463725
53Congenital stationary night blindness (HP:0007642)2.18220368
54Leukodystrophy (HP:0002415)2.16255951
55Aplasia/Hypoplasia of the sacrum (HP:0008517)2.15713845
56Abnormality of the ileum (HP:0001549)2.14503838
57Renal cortical cysts (HP:0000803)2.14154221
58Sclerocornea (HP:0000647)2.13633558
59Gait imbalance (HP:0002141)2.12678937
60Congenital hepatic fibrosis (HP:0002612)2.11564025
61Congenital primary aphakia (HP:0007707)2.09167024
62Stenosis of the external auditory canal (HP:0000402)2.08659943
63Ectropion (HP:0000656)2.07406650
64Cystic liver disease (HP:0006706)2.06978592
65Median cleft lip (HP:0000161)2.05176181
66Abnormal number of erythroid precursors (HP:0012131)2.03829933
67Abnormality of the columella (HP:0009929)2.02260655
68Hypothermia (HP:0002045)2.00952083
69Microvesicular hepatic steatosis (HP:0001414)2.00847136
70Anencephaly (HP:0002323)2.00702087
71Nephrogenic diabetes insipidus (HP:0009806)1.99980941
72Aplasia/Hypoplasia of the tibia (HP:0005772)1.99498300
73Rectal fistula (HP:0100590)1.99247455
74Rectovaginal fistula (HP:0000143)1.99247455
75Abnormal hemoglobin (HP:0011902)1.99153463
76Hyperglycinemia (HP:0002154)1.98464174
77Absent radius (HP:0003974)1.98375912
78Genital tract atresia (HP:0001827)1.98246754
79Aplasia/Hypoplasia of the tongue (HP:0010295)1.98236603
80Acute necrotizing encephalopathy (HP:0006965)1.98113866
81Optic disc pallor (HP:0000543)1.95762913
82Pancreatic cysts (HP:0001737)1.95102003
83Myelodysplasia (HP:0002863)1.94858021
84Cupped ear (HP:0000378)1.94696512
85Acute myeloid leukemia (HP:0004808)1.94507858
86Intestinal atresia (HP:0011100)1.92640198
87True hermaphroditism (HP:0010459)1.92290024
88Mitochondrial inheritance (HP:0001427)1.91936602
89Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.90427219
90Short tibia (HP:0005736)1.89735798
91Ectopic kidney (HP:0000086)1.88406425
92Abolished electroretinogram (ERG) (HP:0000550)1.88213113
93Postaxial hand polydactyly (HP:0001162)1.87905667
94Male pseudohermaphroditism (HP:0000037)1.87786298
95Abnormality of the phalanges of the 2nd finger (HP:0009541)1.87717523
96Nephroblastoma (Wilms tumor) (HP:0002667)1.87148952
97Hypoplasia of the fovea (HP:0007750)1.86914060
98Aplasia/Hypoplasia of the fovea (HP:0008060)1.86914060
99Aplastic anemia (HP:0001915)1.86540306
100Vaginal atresia (HP:0000148)1.85741849
101Abnormal lung lobation (HP:0002101)1.84849050
102Absent thumb (HP:0009777)1.84198753
103Macrocytic anemia (HP:0001972)1.84100332
104Rib fusion (HP:0000902)1.83428617
105Type I transferrin isoform profile (HP:0003642)1.83213959
106Absent septum pellucidum (HP:0001331)1.83089494
107Abnormal respiratory epithelium morphology (HP:0012253)1.82477856
108Abnormal respiratory motile cilium morphology (HP:0005938)1.82477856
109Pancreatic fibrosis (HP:0100732)1.81707328
110Sensory axonal neuropathy (HP:0003390)1.81362135
111Aplasia/Hypoplasia of the uvula (HP:0010293)1.79549742
112Methylmalonic aciduria (HP:0012120)1.79189613
113Adrenal hypoplasia (HP:0000835)1.79130925
114Intestinal fistula (HP:0100819)1.79018591
115Anophthalmia (HP:0000528)1.78310212
116Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.78169159
117Triphalangeal thumb (HP:0001199)1.76961369
118Pancytopenia (HP:0001876)1.76843655
119Abnormal drinking behavior (HP:0030082)1.76728043
120Polydipsia (HP:0001959)1.76728043
121Small intestinal stenosis (HP:0012848)1.76642640
122Duodenal stenosis (HP:0100867)1.76642640
123Exertional dyspnea (HP:0002875)1.75840788
124Anhidrosis (HP:0000970)1.75396451
125Bile duct proliferation (HP:0001408)1.75172914
126Abnormal biliary tract physiology (HP:0012439)1.75172914
127Aplasia involving forearm bones (HP:0009822)1.74785122
128Absent forearm bone (HP:0003953)1.74785122
129Pallor (HP:0000980)1.74772734
130Gaze-evoked nystagmus (HP:0000640)1.74651437
131Erythroderma (HP:0001019)1.74233151
132Growth hormone deficiency (HP:0000824)1.74047290
133Preaxial hand polydactyly (HP:0001177)1.74041586
134Agnosia (HP:0010524)1.74019977
135Abnormality of the fovea (HP:0000493)1.73911861
136Meckel diverticulum (HP:0002245)1.73329113
137Supernumerary bones of the axial skeleton (HP:0009144)1.72925562
138Dry hair (HP:0011359)1.72889636
139Aplasia/Hypoplasia of the earlobes (HP:0009906)1.72316508
140Thyroiditis (HP:0100646)1.72277958
141Progressive macrocephaly (HP:0004481)1.72012956
142Abnormality of the septum pellucidum (HP:0007375)1.71957990
143Colon cancer (HP:0003003)1.71599655
144Enlarged kidneys (HP:0000105)1.71507483
145Embryonal renal neoplasm (HP:0011794)1.71324415
146Abnormality of the heme biosynthetic pathway (HP:0010472)1.71213584
147Abnormality of cochlea (HP:0000375)1.71075430
148Abnormality of renal resorption (HP:0011038)1.70259361
149Respiratory failure (HP:0002878)1.70059482
150Progressive inability to walk (HP:0002505)1.69503474
151Optic nerve hypoplasia (HP:0000609)1.69400909
152Tubular atrophy (HP:0000092)1.69221905
153Abnormality of the incisor (HP:0000676)1.68704645
154Medial flaring of the eyebrow (HP:0010747)1.68253600
155Postaxial foot polydactyly (HP:0001830)1.68159864
156Sloping forehead (HP:0000340)1.68007084
157Tubulointerstitial nephritis (HP:0001970)1.66143418
158Clubbing of toes (HP:0100760)1.65850939
159Abnormal spermatogenesis (HP:0008669)1.65145109
160Metaphyseal dysplasia (HP:0100255)1.64752207
161Increased CSF lactate (HP:0002490)1.63253766

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK2.71134335
2MST42.61755813
3WNK32.61233282
4TNIK2.45320562
5STK392.43899124
6MKNK22.37852441
7PNCK2.18202230
8ZAK2.10983445
9CDC72.06410350
10TRIM282.04440505
11MKNK12.04103854
12SRPK12.04061434
13MAP3K41.99291769
14MAP4K21.89881465
15WEE11.87105054
16VRK21.82916155
17NUAK11.72382365
18MAP3K61.65356763
19PLK41.64780719
20NEK61.62359030
21ACVR1B1.60307490
22EIF2AK31.55919994
23MAPK131.53800403
24STK101.52867307
25BRD41.51769189
26PLK21.47366162
27TXK1.45548891
28VRK11.45099757
29OXSR11.43122137
30WNK41.35979142
31FRK1.34489797
32TLK11.34331265
33CDK31.34086744
34TTK1.30295490
35GRK71.29424616
36TEC1.28655699
37STK161.28523092
38CDK91.28460406
39PINK11.28213121
40DYRK21.26338570
41BMPR1B1.25799285
42PIK3CA1.21235241
43MUSK1.20915026
44IRAK41.20533364
45MAP2K71.18876758
46BCR1.18029676
47IRAK31.17150769
48YES11.16928869
49MAPK151.16564279
50FGFR21.14973940
51BRSK21.13720433
52PLK31.10510290
53ADRBK21.09808843
54MAPKAPK51.06432808
55EIF2AK21.04871168
56RPS6KA51.02754913
57MAP3K141.01640201
58AURKB1.00709982
59CASK0.99653722
60DYRK30.98866682
61TRPM70.97813913
62INSRR0.95390884
63ATR0.95138114
64CHEK20.95046170
65OBSCN0.93790422
66TAOK30.92863158
67ATM0.92349703
68MELK0.91916160
69PAK30.91389055
70STK40.90795367
71PASK0.90747466
72PKN10.90595139
73ITK0.90200431
74CDK190.87961700
75NEK90.85805599
76MAP2K30.82207662
77NME10.81924055
78CSNK1G30.81354046
79CLK10.79205481
80STK38L0.79005089
81BUB10.78768282
82AKT30.78761917
83PLK10.78244458
84CSNK1A1L0.77853935
85IRAK10.77052017
86TSSK60.76706182
87PRKCG0.74777923
88LCK0.74714317
89CSNK1G10.74459218
90NLK0.72448213
91NEK20.72196747
92EPHA40.70425625
93MET0.69765384
94CDK80.67607830
95NTRK20.67588500
96RPS6KB20.67234656
97WNK10.65127747
98CDK60.64553562
99NEK10.64287253
100RPS6KA40.63549631
101TGFBR10.63414900
102BTK0.60670499
103NTRK30.59431272
104CSNK1G20.58765938
105PIK3CG0.57877365
106CDK70.57724959
107IKBKB0.56537110
108CSNK1E0.56344835
109IKBKE0.56157327
110CSNK2A20.55865985
111TAF10.55624188
112PRKCQ0.55397390
113CSNK2A10.54742948
114MAP2K40.53316518
115ADRBK10.52414606
116LYN0.52013385
117CSNK1D0.51728370
118ERBB30.51489915
119PRKAA20.51449391
120MARK10.51295515
121IRAK20.51266636
122BCKDK0.49820453
123CHEK10.48589332
124PRKCE0.48402180
125KIT0.47843163
126TGFBR20.47577669
127PIM10.47309635
128CCNB10.47015304
129FGR0.46752877
130CDK120.46527893
131GRK10.45777961
132SGK20.45366043
133STK30.44586285
134CDK10.44550736
135MAP4K10.44533718
136AURKA0.44392344
137PRKACB0.43275627
138PRKG10.43254075
139CAMK1D0.43155775
140TNK20.42310662
141PRKACA0.41467941
142DYRK1A0.41172585
143CAMK2A0.40584592
144MINK10.38802594
145CAMK10.38468389
146SGK10.37583816
147MAP3K120.36799921

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034503.62697336
2Ribosome_Homo sapiens_hsa030103.43843280
3Protein export_Homo sapiens_hsa030603.27799911
4Mismatch repair_Homo sapiens_hsa034302.85113834
5Homologous recombination_Homo sapiens_hsa034402.83519945
6RNA polymerase_Homo sapiens_hsa030202.53774965
7Fanconi anemia pathway_Homo sapiens_hsa034602.48564869
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.45377831
9Nucleotide excision repair_Homo sapiens_hsa034202.21157198
10DNA replication_Homo sapiens_hsa030302.19946090
11Basal transcription factors_Homo sapiens_hsa030222.18197878
12RNA degradation_Homo sapiens_hsa030182.17155712
13Spliceosome_Homo sapiens_hsa030402.12433014
14Oxidative phosphorylation_Homo sapiens_hsa001901.90358880
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.81057580
16Cardiac muscle contraction_Homo sapiens_hsa042601.77349117
17Cell cycle_Homo sapiens_hsa041101.71347753
18Ether lipid metabolism_Homo sapiens_hsa005651.70441602
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.69842799
20Fatty acid elongation_Homo sapiens_hsa000621.66107429
21RNA transport_Homo sapiens_hsa030131.64325466
22Proteasome_Homo sapiens_hsa030501.58909867
23Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.54482361
24Systemic lupus erythematosus_Homo sapiens_hsa053221.54465031
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.53393216
26Pyrimidine metabolism_Homo sapiens_hsa002401.45767134
27Base excision repair_Homo sapiens_hsa034101.45074830
28Parkinsons disease_Homo sapiens_hsa050121.41111655
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.34565842
30Sphingolipid metabolism_Homo sapiens_hsa006001.31366857
31Nicotine addiction_Homo sapiens_hsa050331.27586490
32Vitamin B6 metabolism_Homo sapiens_hsa007501.20646018
33Huntingtons disease_Homo sapiens_hsa050161.16309450
34Primary immunodeficiency_Homo sapiens_hsa053401.15567702
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.14630610
36mRNA surveillance pathway_Homo sapiens_hsa030151.13508666
37Arachidonic acid metabolism_Homo sapiens_hsa005901.13384842
38One carbon pool by folate_Homo sapiens_hsa006701.11355357
39NOD-like receptor signaling pathway_Homo sapiens_hsa046211.10945978
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.09443475
41Linoleic acid metabolism_Homo sapiens_hsa005911.08454237
42NF-kappa B signaling pathway_Homo sapiens_hsa040641.05372905
43Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.04713848
44Alzheimers disease_Homo sapiens_hsa050101.03515458
45Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.00187135
46Autoimmune thyroid disease_Homo sapiens_hsa053200.98171525
47Transcriptional misregulation in cancer_Homo sapiens_hsa052020.97982531
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95422971
49Steroid biosynthesis_Homo sapiens_hsa001000.94658646
50Butanoate metabolism_Homo sapiens_hsa006500.94189189
51Hematopoietic cell lineage_Homo sapiens_hsa046400.94031190
52Allograft rejection_Homo sapiens_hsa053300.93011070
53Purine metabolism_Homo sapiens_hsa002300.92857961
54Olfactory transduction_Homo sapiens_hsa047400.90727988
55Selenocompound metabolism_Homo sapiens_hsa004500.88154972
56Histidine metabolism_Homo sapiens_hsa003400.87113212
57Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.85863319
58Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.85471755
59Herpes simplex infection_Homo sapiens_hsa051680.84808908
60Retinol metabolism_Homo sapiens_hsa008300.83404265
61Collecting duct acid secretion_Homo sapiens_hsa049660.82902271
62p53 signaling pathway_Homo sapiens_hsa041150.82119066
63Regulation of autophagy_Homo sapiens_hsa041400.81616034
64Primary bile acid biosynthesis_Homo sapiens_hsa001200.81350583
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81325448
66Tryptophan metabolism_Homo sapiens_hsa003800.80318543
67Staphylococcus aureus infection_Homo sapiens_hsa051500.79398356
68Chemical carcinogenesis_Homo sapiens_hsa052040.77753194
69Caffeine metabolism_Homo sapiens_hsa002320.76427297
70Taste transduction_Homo sapiens_hsa047420.76202595
71RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74493629
72Epstein-Barr virus infection_Homo sapiens_hsa051690.74453467
73Malaria_Homo sapiens_hsa051440.74181846
74SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70722643
75Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.70229644
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67459877
77Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.67380273
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.66490328
79Measles_Homo sapiens_hsa051620.65764868
80Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.65424942
81Glutathione metabolism_Homo sapiens_hsa004800.65155790
82Graft-versus-host disease_Homo sapiens_hsa053320.64709158
83Oocyte meiosis_Homo sapiens_hsa041140.64589083
84Tyrosine metabolism_Homo sapiens_hsa003500.64112849
85Nitrogen metabolism_Homo sapiens_hsa009100.63504975
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.63007611
87Intestinal immune network for IgA production_Homo sapiens_hsa046720.62210377
88TGF-beta signaling pathway_Homo sapiens_hsa043500.60917055
89Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59516966
90Antigen processing and presentation_Homo sapiens_hsa046120.59257431
91Sulfur metabolism_Homo sapiens_hsa009200.58430514
92Maturity onset diabetes of the young_Homo sapiens_hsa049500.58129281
93Asthma_Homo sapiens_hsa053100.58101802
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.56111576
95Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.55147952
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54376396
97Folate biosynthesis_Homo sapiens_hsa007900.53955634
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52717462
99Phototransduction_Homo sapiens_hsa047440.51976499
100Metabolic pathways_Homo sapiens_hsa011000.51674257
101Morphine addiction_Homo sapiens_hsa050320.51266625
102GABAergic synapse_Homo sapiens_hsa047270.49899511
103Viral carcinogenesis_Homo sapiens_hsa052030.49450606
104Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49040746
105Vitamin digestion and absorption_Homo sapiens_hsa049770.48464496
106Serotonergic synapse_Homo sapiens_hsa047260.48271067
107ABC transporters_Homo sapiens_hsa020100.47615066
108Hedgehog signaling pathway_Homo sapiens_hsa043400.45927634
109Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45072754
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44525016
111Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42729811
112Basal cell carcinoma_Homo sapiens_hsa052170.39767839
113Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.37549120
114Alcoholism_Homo sapiens_hsa050340.36078227
115Drug metabolism - other enzymes_Homo sapiens_hsa009830.35501118
116Pyruvate metabolism_Homo sapiens_hsa006200.35477228
117Glutamatergic synapse_Homo sapiens_hsa047240.35436884
118Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.34826808
119Ovarian steroidogenesis_Homo sapiens_hsa049130.34057295
120Rheumatoid arthritis_Homo sapiens_hsa053230.33994196
121Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32409702
122Jak-STAT signaling pathway_Homo sapiens_hsa046300.31942767
123Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31825396
124Peroxisome_Homo sapiens_hsa041460.31805582
125Circadian entrainment_Homo sapiens_hsa047130.31624098
126African trypanosomiasis_Homo sapiens_hsa051430.31294765
127Circadian rhythm_Homo sapiens_hsa047100.31246178
128Wnt signaling pathway_Homo sapiens_hsa043100.30199805
129beta-Alanine metabolism_Homo sapiens_hsa004100.26793052
130Propanoate metabolism_Homo sapiens_hsa006400.25634495
131Toll-like receptor signaling pathway_Homo sapiens_hsa046200.25117347
132Insulin secretion_Homo sapiens_hsa049110.24151954
133Arginine and proline metabolism_Homo sapiens_hsa003300.23764313
134MicroRNAs in cancer_Homo sapiens_hsa052060.23277791
135Dopaminergic synapse_Homo sapiens_hsa047280.21137880
136Dorso-ventral axis formation_Homo sapiens_hsa043200.18589528

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