CX3CL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.47084046
2synaptic vesicle maturation (GO:0016188)6.34231362
3positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.07773835
4locomotory exploration behavior (GO:0035641)6.03417595
5vocalization behavior (GO:0071625)5.62068243
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.46503767
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.46484167
8synaptic vesicle exocytosis (GO:0016079)5.44842180
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.41809073
10glutamate secretion (GO:0014047)5.35538026
11regulation of glutamate receptor signaling pathway (GO:1900449)5.20734964
12regulation of synaptic vesicle exocytosis (GO:2000300)5.03067793
13regulation of long-term neuronal synaptic plasticity (GO:0048169)5.00132048
14regulation of neuronal synaptic plasticity (GO:0048168)4.95134103
15ionotropic glutamate receptor signaling pathway (GO:0035235)4.85108733
16protein localization to synapse (GO:0035418)4.76400648
17regulation of synapse structural plasticity (GO:0051823)4.75296124
18exploration behavior (GO:0035640)4.61074931
19neuronal action potential propagation (GO:0019227)4.54662228
20regulation of synaptic vesicle transport (GO:1902803)4.51975118
21neurotransmitter secretion (GO:0007269)4.41211926
22synaptic transmission, glutamatergic (GO:0035249)4.33888229
23dendritic spine morphogenesis (GO:0060997)4.29046500
24neurotransmitter-gated ion channel clustering (GO:0072578)4.28397563
25regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.25053262
26glutamate receptor signaling pathway (GO:0007215)4.18289147
27long-term memory (GO:0007616)4.10997886
28neuron-neuron synaptic transmission (GO:0007270)4.10439273
29regulation of excitatory postsynaptic membrane potential (GO:0060079)4.10293737
30layer formation in cerebral cortex (GO:0021819)4.07369232
31positive regulation of membrane potential (GO:0045838)4.04842140
32regulation of dendritic spine morphogenesis (GO:0061001)4.01322212
33membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.01120781
34neuron cell-cell adhesion (GO:0007158)3.97841061
35regulation of synaptic plasticity (GO:0048167)3.97179564
36cellular potassium ion homeostasis (GO:0030007)3.88217706
37regulation of postsynaptic membrane potential (GO:0060078)3.85412292
38G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.83613563
39proline transport (GO:0015824)3.74576115
40long-term synaptic potentiation (GO:0060291)3.73064990
41gamma-aminobutyric acid transport (GO:0015812)3.69921086
42neuromuscular process controlling balance (GO:0050885)3.69683940
43positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.68387168
44positive regulation of neurotransmitter secretion (GO:0001956)3.65694776
45sodium ion export (GO:0071436)3.64626784
46activation of protein kinase A activity (GO:0034199)3.63374405
47positive regulation of neurotransmitter transport (GO:0051590)3.58795218
48regulation of synapse maturation (GO:0090128)3.57172617
49positive regulation of synapse maturation (GO:0090129)3.54852358
50regulation of apoptotic cell clearance (GO:2000425)3.52619655
51positive regulation of synaptic transmission, GABAergic (GO:0032230)3.51433909
52regulation of synaptic transmission, glutamatergic (GO:0051966)3.50526898
53neurotransmitter transport (GO:0006836)3.48450146
54prepulse inhibition (GO:0060134)3.47009628
55regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.43214078
56auditory behavior (GO:0031223)3.43204919
57regulation of neurotransmitter secretion (GO:0046928)3.41148360
58transmission of nerve impulse (GO:0019226)3.37595779
59dendritic spine organization (GO:0097061)3.37518632
60regulation of vesicle fusion (GO:0031338)3.33688259
61regulation of dendritic spine development (GO:0060998)3.32703850
62behavioral defense response (GO:0002209)3.30151683
63behavioral fear response (GO:0001662)3.30151683
64neuron recognition (GO:0008038)3.29833767
65gamma-aminobutyric acid signaling pathway (GO:0007214)3.28410309
66regulation of neurotransmitter levels (GO:0001505)3.27017917
67response to auditory stimulus (GO:0010996)3.26757536
68negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.23499943
69cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.22788422
70cerebellar granule cell differentiation (GO:0021707)3.22274014
71synaptic vesicle endocytosis (GO:0048488)3.21945468
72membrane depolarization (GO:0051899)3.20605621
73response to histamine (GO:0034776)3.20506036
74neuronal ion channel clustering (GO:0045161)3.19764364
75regulation of neurotransmitter transport (GO:0051588)3.19749918
76positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.18377836
77negative regulation of fibrinolysis (GO:0051918)3.17584583
78glycine transport (GO:0015816)3.17206663
79negative regulation of synaptic transmission, GABAergic (GO:0032229)3.16792838
80membrane hyperpolarization (GO:0060081)3.16734854
81positive regulation of synaptic transmission (GO:0050806)3.16661746
82learning (GO:0007612)3.16352882
83neuromuscular process controlling posture (GO:0050884)3.15942349
84regulation of female receptivity (GO:0045924)3.12070799
85regulation of glutamate secretion (GO:0014048)3.11072878
86positive regulation of dendritic spine development (GO:0060999)3.10737638
87cellular sodium ion homeostasis (GO:0006883)3.10564427
88cell communication by electrical coupling (GO:0010644)3.10318563
89regulation of synaptic transmission (GO:0050804)3.08698086
90axonal fasciculation (GO:0007413)3.07448392
91fear response (GO:0042596)3.06171726
92lung epithelium development (GO:0060428)3.05250354
93behavioral response to cocaine (GO:0048148)3.05084921
94innervation (GO:0060384)3.03605614
95vesicle transport along microtubule (GO:0047496)3.03166772
96regulation of voltage-gated calcium channel activity (GO:1901385)3.02571721
97cerebellar Purkinje cell differentiation (GO:0021702)3.02485072
98neuromuscular process (GO:0050905)3.01896937
99long term synaptic depression (GO:0060292)2.99031752
100chemosensory behavior (GO:0007635)2.97460277
101cytoskeletal anchoring at plasma membrane (GO:0007016)2.96831529
102postsynaptic membrane organization (GO:0001941)2.96794512
103membrane depolarization during action potential (GO:0086010)2.96403720
104synaptic transmission (GO:0007268)2.96280925
105negative regulation of amino acid transport (GO:0051956)2.95689112
106visual learning (GO:0008542)2.94952267
107positive regulation of dendritic spine morphogenesis (GO:0061003)2.94885707
108regulation of protein activation cascade (GO:2000257)2.80841428
109regulation of complement activation (GO:0030449)2.80440055
110cell-cell junction maintenance (GO:0045217)2.72973912
111peptidyl-glutamic acid carboxylation (GO:0017187)2.70647005
112protein carboxylation (GO:0018214)2.70647005
113regulation of fibrinolysis (GO:0051917)2.70039946
114regulation of sodium ion transmembrane transporter activity (GO:2000649)2.57965002
115intestinal cholesterol absorption (GO:0030299)2.55455567
116regulation of cholesterol biosynthetic process (GO:0045540)2.54385111
117central nervous system myelination (GO:0022010)2.51532248
118axon ensheathment in central nervous system (GO:0032291)2.51532248
119L-phenylalanine catabolic process (GO:0006559)2.51198799
120erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.51198799
121sodium ion homeostasis (GO:0055078)2.51172241
122neuron remodeling (GO:0016322)2.50438692
123L-amino acid import (GO:0043092)2.49919167
124cell communication involved in cardiac conduction (GO:0086065)2.48845633
125positive regulation of dendrite development (GO:1900006)2.44632378
126regulation of plasminogen activation (GO:0010755)2.43421960
127cell volume homeostasis (GO:0006884)2.39560863
128amino acid import (GO:0043090)2.36949182
129regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.36540393
130embryonic retina morphogenesis in camera-type eye (GO:0060059)2.35702348
131cell junction maintenance (GO:0034331)2.35314348
132endothelial cell chemotaxis (GO:0035767)2.29525284
133insulin-like growth factor receptor signaling pathway (GO:0048009)2.24575805
134negative regulation of dendrite morphogenesis (GO:0050774)2.23772867
135blood coagulation, intrinsic pathway (GO:0007597)2.23718055
136regulation of ARF protein signal transduction (GO:0032012)2.23489379
137erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.22126599
138L-phenylalanine metabolic process (GO:0006558)2.22126599
139negative regulation of catenin import into nucleus (GO:0035414)2.22094578
140protein-lipid complex remodeling (GO:0034368)2.20576103
141macromolecular complex remodeling (GO:0034367)2.20576103
142plasma lipoprotein particle remodeling (GO:0034369)2.20576103
143reverse cholesterol transport (GO:0043691)2.19623993
144regulation of sodium ion transmembrane transport (GO:1902305)2.18427343
145low-density lipoprotein particle remodeling (GO:0034374)2.17359394
146potassium ion homeostasis (GO:0055075)2.14589706
147nephron epithelium morphogenesis (GO:0072088)2.13435054
148nephron tubule morphogenesis (GO:0072078)2.13435054

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.93684609
2* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.19351634
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.16656812
4GBX2_23144817_ChIP-Seq_PC3_Human3.16597904
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.10492876
6* RARB_27405468_Chip-Seq_BRAIN_Mouse3.08990202
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.85049603
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.85049603
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.77246598
10* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.71127843
11DROSHA_22980978_ChIP-Seq_HELA_Human2.70887043
12REST_21632747_ChIP-Seq_MESCs_Mouse2.68731103
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.63663847
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.61170928
15* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.52831414
16* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.52398187
17ESR2_21235772_ChIP-Seq_MCF-7_Human2.46576986
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.46207174
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.37152637
20IKZF1_21737484_ChIP-ChIP_HCT116_Human2.36242125
21MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.35582633
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.28533343
23EED_16625203_ChIP-ChIP_MESCs_Mouse2.27287231
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.25598082
25ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.25104872
26* REST_18959480_ChIP-ChIP_MESCs_Mouse2.21572903
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.11115137
28ESR1_21235772_ChIP-Seq_MCF-7_Human2.08533990
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.90437820
30AR_21572438_ChIP-Seq_LNCaP_Human1.81059768
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.81002191
32TRIM28_21343339_ChIP-Seq_HEK293_Human1.80577509
33NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.79466918
34ERG_21242973_ChIP-ChIP_JURKAT_Human1.79231813
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.71728258
36FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.69398557
37LXR_22292898_ChIP-Seq_THP-1_Human1.62472457
38RXR_22158963_ChIP-Seq_LIVER_Mouse1.58224746
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.54867028
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54617575
41TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.51251538
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.50251645
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.50177555
44SMAD4_21799915_ChIP-Seq_A2780_Human1.47296196
45FOXA2_19822575_ChIP-Seq_HepG2_Human1.43875306
46DNAJC2_21179169_ChIP-ChIP_NT2_Human1.42870906
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41218877
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.41139591
49LXR_22158963_ChIP-Seq_LIVER_Mouse1.38441100
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.37792255
51ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.36711195
52ESR1_20079471_ChIP-ChIP_T-47D_Human1.35870330
53PPARA_22158963_ChIP-Seq_LIVER_Mouse1.33848899
54TAF15_26573619_Chip-Seq_HEK293_Human1.33002467
55RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.32563609
56TP63_17297297_ChIP-ChIP_HaCaT_Human1.29480402
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.27884468
58WT1_25993318_ChIP-Seq_PODOCYTE_Human1.27189640
59KDM2B_26808549_Chip-Seq_K562_Human1.26789297
60* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.26656078
61TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.26469929
62PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26279025
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25866834
64PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.25667271
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23364535
66* SOX2_21211035_ChIP-Seq_LN229_Gbm1.23281406
67ZFP281_18757296_ChIP-ChIP_E14_Mouse1.21343870
68EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.20534297
69PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.19608175
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.18807942
71AR_19668381_ChIP-Seq_PC3_Human1.18758195
72PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18295213
73ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15304191
74SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.14450237
75RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14342516
76RING1B_27294783_Chip-Seq_NPCs_Mouse1.13638297
77SMC4_20622854_ChIP-Seq_HELA_Human1.13036115
78AR_25329375_ChIP-Seq_VCAP_Human1.12164186
79ZNF274_21170338_ChIP-Seq_K562_Hela1.11564127
80P300_19829295_ChIP-Seq_ESCs_Human1.10925468
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10568600
82P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10163656
83* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08762021
84TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05680534
85* STAT3_23295773_ChIP-Seq_U87_Human1.05282145
86SMAD3_21741376_ChIP-Seq_HESCs_Human1.03927685
87NFIB_24661679_ChIP-Seq_LUNG_Mouse1.03808574
88VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.03643703
89EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02474895
90ZNF263_19887448_ChIP-Seq_K562_Human1.02307614
91BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01976764
92GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01917911
93CTNNB1_20460455_ChIP-Seq_HCT116_Human1.01297408
94AHR_22903824_ChIP-Seq_MCF-7_Human1.00793014
95ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00692923
96ARNT_22903824_ChIP-Seq_MCF-7_Human1.00478421
97CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00311881
98RAD21_21589869_ChIP-Seq_MESCs_Mouse1.00009321
99SOX9_24532713_ChIP-Seq_HFSC_Mouse0.98892118
100RACK7_27058665_Chip-Seq_MCF-7_Human0.98694487
101TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98194188
102SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97171795
103YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96940853
104* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96667794
105RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96347403
106RXR_22108803_ChIP-Seq_LS180_Human0.96015521
107PIAS1_25552417_ChIP-Seq_VCAP_Human0.95785845
108TP53_16413492_ChIP-PET_HCT116_Human0.95617795
109CDX2_19796622_ChIP-Seq_MESCs_Mouse0.95581403
110PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.95406796
111CDX2_20551321_ChIP-Seq_CACO-2_Human0.94578065
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94524454
113OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94445513
114* CREB1_26743006_Chip-Seq_LNCaP_Human0.94251640
115ZFP281_27345836_Chip-Seq_ESCs_Mouse0.94041326
116OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93955813
117ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93799185
118TCF4_23295773_ChIP-Seq_U87_Human0.93573959
119P68_20966046_ChIP-Seq_HELA_Human0.93480589
120PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92017081
121CTCF_27219007_Chip-Seq_Bcells_Human0.91535972
122CBX2_27304074_Chip-Seq_ESCs_Mouse0.91477752
123PRDM14_20953172_ChIP-Seq_ESCs_Human0.90982613
124SMAD4_21741376_ChIP-Seq_HESCs_Human0.90729937
125SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90035238
126OCT4_19829295_ChIP-Seq_ESCs_Human0.89602677
127TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89130616
128SMAD3_21741376_ChIP-Seq_ESCs_Human0.88535384
129TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87906773
130ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.87784645
131TP53_23651856_ChIP-Seq_MEFs_Mouse0.87560518
132TET1_21490601_ChIP-Seq_MESCs_Mouse0.87131784
133RUNX1_27514584_Chip-Seq_MCF-7_Human0.86775447
134THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86558958
135NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85643902
136ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.85255907
137RUNX2_22187159_ChIP-Seq_PCA_Human0.83488602
138EP300_21415370_ChIP-Seq_HL-1_Mouse0.83327875
139AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.82328800
140SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82304799
141MYC_27129775_Chip-Seq_CORNEA_Mouse0.81756910
142TP53_20018659_ChIP-ChIP_R1E_Mouse0.81167968
143TP63_22573176_ChIP-Seq_HFKS_Human0.80983462
144KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80722888
145KLF4_19829295_ChIP-Seq_ESCs_Human0.79136683
146BMI1_23680149_ChIP-Seq_NPCS_Mouse0.78186887

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.55785283
2MP0003880_abnormal_central_pattern5.00515400
3MP0003635_abnormal_synaptic_transmissio4.47238641
4MP0002822_catalepsy4.38097972
5MP0000566_synostosis3.88352834
6MP0004270_analgesia3.73526256
7MP0009745_abnormal_behavioral_response3.72983914
8MP0002063_abnormal_learning/memory/cond3.61682561
9MP0002064_seizures3.32017293
10MP0009046_muscle_twitch2.90089882
11MP0002572_abnormal_emotion/affect_behav2.90079915
12MP0001968_abnormal_touch/_nociception2.88535009
13MP0001486_abnormal_startle_reflex2.61265865
14MP0005423_abnormal_somatic_nervous2.59851646
15MP0002272_abnormal_nervous_system2.58432490
16MP0001501_abnormal_sleep_pattern2.48456980
17MP0002734_abnormal_mechanical_nocicepti2.40006896
18MP0002736_abnormal_nociception_after2.16012160
19MP0009780_abnormal_chondrocyte_physiolo2.05737890
20MP0001440_abnormal_grooming_behavior1.99867954
21MP0005365_abnormal_bile_salt1.97659582
22MP0002909_abnormal_adrenal_gland1.95160532
23MP0005670_abnormal_white_adipose1.94697991
24* MP0010329_abnormal_lipoprotein_level1.88813491
25MP0003195_calcinosis1.88763799
26MP0003329_amyloid_beta_deposits1.88672213
27MP0002139_abnormal_hepatobiliary_system1.88087002
28MP0008569_lethality_at_weaning1.85877776
29MP0001970_abnormal_pain_threshold1.83964114
30MP0004858_abnormal_nervous_system1.83940940
31MP0002733_abnormal_thermal_nociception1.82989847
32MP0002735_abnormal_chemical_nociception1.79505002
33MP0004811_abnormal_neuron_physiology1.78650872
34MP0008875_abnormal_xenobiotic_pharmacok1.77956446
35MP0002067_abnormal_sensory_capabilities1.73140113
36MP0005360_urolithiasis1.71394123
37MP0003879_abnormal_hair_cell1.69763458
38MP0002557_abnormal_social/conspecific_i1.68727177
39MP0005386_behavior/neurological_phenoty1.66102433
40MP0004924_abnormal_behavior1.66102433
41MP0005646_abnormal_pituitary_gland1.63735369
42MP0002184_abnormal_innervation1.51298247
43MP0000778_abnormal_nervous_system1.45904944
44MP0004885_abnormal_endolymph1.42723048
45MP0003633_abnormal_nervous_system1.40164591
46MP0000955_abnormal_spinal_cord1.39415340
47MP0001529_abnormal_vocalization1.38564951
48MP0002066_abnormal_motor_capabilities/c1.36533988
49MP0001984_abnormal_olfaction1.36457466
50MP0003787_abnormal_imprinting1.29369150
51MP0002882_abnormal_neuron_morphology1.29161215
52MP0002089_abnormal_postnatal_growth/wei1.27832009
53MP0001502_abnormal_circadian_rhythm1.25115460
54MP0008872_abnormal_physiological_respon1.16630719
55MP0001905_abnormal_dopamine_level1.16356683
56MP0010234_abnormal_vibrissa_follicle1.15960026
57MP0003123_paternal_imprinting1.14527671
58MP0003631_nervous_system_phenotype1.13409830
59MP0002249_abnormal_larynx_morphology1.12926635
60MP0005171_absent_coat_pigmentation1.11285676
61MP0001177_atelectasis1.09540212
62MP0008961_abnormal_basal_metabolism1.09093953
63MP0008874_decreased_physiological_sensi1.08567866
64* MP0003075_altered_response_to1.07289330
65MP0003283_abnormal_digestive_organ1.05744763
66MP0000013_abnormal_adipose_tissue1.05370324
67MP0000751_myopathy1.03655212
68MP0005167_abnormal_blood-brain_barrier1.03190905
69MP0010368_abnormal_lymphatic_system1.00957759
70MP0002152_abnormal_brain_morphology1.00270115
71MP0005085_abnormal_gallbladder_physiolo1.00004767
72MP0006276_abnormal_autonomic_nervous0.98384893
73MP0001958_emphysema0.98161231
74MP0004142_abnormal_muscle_tone0.97416765
75MP0002069_abnormal_eating/drinking_beha0.96556310
76MP0005645_abnormal_hypothalamus_physiol0.96370382
77MP0004130_abnormal_muscle_cell0.95572139
78MP0001666_abnormal_nutrient_absorption0.94472798
79MP0001348_abnormal_lacrimal_gland0.92832521
80MP0001188_hyperpigmentation0.92656337
81MP0005076_abnormal_cell_differentiation0.92516145
82MP0005275_abnormal_skin_tensile0.92367118
83* MP0002118_abnormal_lipid_homeostasis0.91327002
84MP0003045_fibrosis0.89260765
85MP0003690_abnormal_glial_cell0.88704082
86MP0000604_amyloidosis0.86923144
87MP0005535_abnormal_body_temperature0.86860864
88MP0004085_abnormal_heartbeat0.86745159
89MP0000639_abnormal_adrenal_gland0.85478808
90MP0004510_myositis0.84821269
91MP0000569_abnormal_digit_pigmentation0.83472156
92MP0002090_abnormal_vision0.82983505
93MP0003252_abnormal_bile_duct0.81905964
94MP0003183_abnormal_peptide_metabolism0.80833073
95MP0004019_abnormal_vitamin_homeostasis0.80315116
96MP0003122_maternal_imprinting0.80244665
97MP0005623_abnormal_meninges_morphology0.79085602
98MP0002638_abnormal_pupillary_reflex0.77123702
99MP0002229_neurodegeneration0.77106984
100MP0010386_abnormal_urinary_bladder0.74440737
101MP0000920_abnormal_myelination0.73704208
102MP0003868_abnormal_feces_composition0.73105278
103MP0003634_abnormal_glial_cell0.72807530
104MP0000003_abnormal_adipose_tissue0.72743442
105MP0001756_abnormal_urination0.72504545
106MP0005503_abnormal_tendon_morphology0.71071717
107MP0002933_joint_inflammation0.70582833
108MP0000026_abnormal_inner_ear0.70574686
109MP0003632_abnormal_nervous_system0.70279653
110MP0001664_abnormal_digestion0.69581677
111MP0004133_heterotaxia0.69215250
112MP0002254_reproductive_system_inflammat0.68609036
113MP0005409_darkened_coat_color0.68597567
114MP0009840_abnormal_foam_cell0.68540842
115MP0004484_altered_response_of0.67256071
116MP0005448_abnormal_energy_balance0.66364984
117MP0005551_abnormal_eye_electrophysiolog0.65387056
118MP0001963_abnormal_hearing_physiology0.64074375
119MP0005499_abnormal_olfactory_system0.63715504
120MP0005394_taste/olfaction_phenotype0.63715504
121MP0004145_abnormal_muscle_electrophysio0.61241285
122MP0004742_abnormal_vestibular_system0.59870079
123MP0002837_dystrophic_cardiac_calcinosis0.59163029
124MP0004043_abnormal_pH_regulation0.58352900
125MP0004215_abnormal_myocardial_fiber0.57333089
126MP0001765_abnormal_ion_homeostasis0.56787372
127MP0000631_abnormal_neuroendocrine_gland0.56617043
128MP0003137_abnormal_impulse_conducting0.55291911
129MP0001485_abnormal_pinna_reflex0.54595747
130MP0004233_abnormal_muscle_weight0.54479542
131MP0003172_abnormal_lysosome_physiology0.53694178
132MP0001943_abnormal_respiration0.52651315
133MP0002752_abnormal_somatic_nervous0.51733622
134MP0002876_abnormal_thyroid_physiology0.50249577
135MP0010769_abnormal_survival0.47483122
136MP0003956_abnormal_body_size0.47247538
137MP0010770_preweaning_lethality0.44442870

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.37637876
2Myokymia (HP:0002411)8.11136934
3Focal seizures (HP:0007359)6.10244150
4Visual hallucinations (HP:0002367)5.34771649
5Deep venous thrombosis (HP:0002625)5.16540485
6Epileptic encephalopathy (HP:0200134)4.89106328
7Atonic seizures (HP:0010819)4.53822579
8Febrile seizures (HP:0002373)4.29592907
9Absence seizures (HP:0002121)4.14623377
10Progressive cerebellar ataxia (HP:0002073)3.96532808
11Generalized tonic-clonic seizures (HP:0002069)3.95487626
12Action tremor (HP:0002345)3.81778621
13Dialeptic seizures (HP:0011146)3.80888617
14Bronchomalacia (HP:0002780)3.77336759
15Poor eye contact (HP:0000817)3.75047960
16Complement deficiency (HP:0004431)3.71349778
17Impaired vibration sensation in the lower limbs (HP:0002166)3.71299497
18Ankle clonus (HP:0011448)3.55376681
19Broad-based gait (HP:0002136)3.54581655
20Depression (HP:0000716)3.48020769
21Glomerulonephritis (HP:0000099)3.41933400
22Gaze-evoked nystagmus (HP:0000640)3.39660161
23Abnormal social behavior (HP:0012433)3.39255204
24Impaired social interactions (HP:0000735)3.39255204
25Supranuclear gaze palsy (HP:0000605)3.37277020
26Anxiety (HP:0000739)3.31473471
27Dysdiadochokinesis (HP:0002075)3.29566216
28Urinary bladder sphincter dysfunction (HP:0002839)3.28097770
29Alacrima (HP:0000522)3.25863992
30Dysmetria (HP:0001310)3.23579872
31Joint hemorrhage (HP:0005261)3.23047157
32Torticollis (HP:0000473)3.21984901
33Papilledema (HP:0001085)3.21365932
34Sleep apnea (HP:0010535)3.16487521
35Postural instability (HP:0002172)3.16334693
36Peripheral hypomyelination (HP:0007182)3.06080532
37Amblyopia (HP:0000646)3.05431706
38Annular pancreas (HP:0001734)3.01376951
39Abnormality of the lower motor neuron (HP:0002366)3.01122778
40Abnormal eating behavior (HP:0100738)3.00929122
41Focal dystonia (HP:0004373)2.98945204
42Hyperventilation (HP:0002883)2.98833880
43Systemic lupus erythematosus (HP:0002725)2.89180237
44Truncal ataxia (HP:0002078)2.87970480
45Mutism (HP:0002300)2.83907221
46Urinary urgency (HP:0000012)2.81689974
47Stereotypic behavior (HP:0000733)2.80755504
48Hemorrhage of the eye (HP:0011885)2.80580070
49Impaired smooth pursuit (HP:0007772)2.78861808
50Abnormality of complement system (HP:0005339)2.73742009
51Ventricular fibrillation (HP:0001663)2.73006837
52Prolonged partial thromboplastin time (HP:0003645)2.70654672
53Morphological abnormality of the inner ear (HP:0011390)2.69635206
54Genetic anticipation (HP:0003743)2.69455001
55Cerebral aneurysm (HP:0004944)2.68140784
56Craniofacial dystonia (HP:0012179)2.66476103
57Hemiplegia (HP:0002301)2.63941922
58Scanning speech (HP:0002168)2.58267443
59Dysmetric saccades (HP:0000641)2.58233426
60Xanthomatosis (HP:0000991)2.58230417
61Intention tremor (HP:0002080)2.56980808
62Bradykinesia (HP:0002067)2.56578776
63Impaired vibratory sensation (HP:0002495)2.52034928
64Cerebral inclusion bodies (HP:0100314)2.50663876
65Spastic gait (HP:0002064)2.49753465
66Aplasia involving bones of the upper limbs (HP:0009823)2.49163047
67Megalencephaly (HP:0001355)2.45820976
68Hemiparesis (HP:0001269)2.44186466
69Resting tremor (HP:0002322)2.43892960
70Neurofibrillary tangles (HP:0002185)2.42933879
71Abnormality of aromatic amino acid family metabolism (HP:0004338)2.42537872
72Pointed chin (HP:0000307)2.41672561
73Drooling (HP:0002307)2.40638123
74Excessive salivation (HP:0003781)2.40638123
75Epileptiform EEG discharges (HP:0011182)2.39974703
76Akinesia (HP:0002304)2.39610506
77Ankyloglossia (HP:0010296)2.39374246
78Abnormality of ocular smooth pursuit (HP:0000617)2.36815824
79Hypoplasia of the iris (HP:0007676)2.36423865
80Status epilepticus (HP:0002133)2.30570223
81Progressive inability to walk (HP:0002505)2.30485593
82Bundle branch block (HP:0011710)2.29883771
83Diplopia (HP:0000651)2.29326474
84Abnormality of binocular vision (HP:0011514)2.29326474
85Lower limb amyotrophy (HP:0007210)2.26716178
86Nephritis (HP:0000123)2.25894233
87Decreased lacrimation (HP:0000633)2.22040695
88Lymphangioma (HP:0100764)2.22003673
89EEG with generalized epileptiform discharges (HP:0011198)2.21732963
90Muscle fiber splitting (HP:0003555)2.19638347
91Heterochromia iridis (HP:0001100)2.16678154
92Lower limb muscle weakness (HP:0007340)2.15329632
93Incomplete penetrance (HP:0003829)2.14179162
94Obstructive sleep apnea (HP:0002870)2.13301323
95Fetal akinesia sequence (HP:0001989)2.11608530
96Generalized myoclonic seizures (HP:0002123)2.10927620
97Hypsarrhythmia (HP:0002521)2.10863962
98Absent speech (HP:0001344)2.08314895
99Hypercholesterolemia (HP:0003124)2.04213468
100Cerebral hypomyelination (HP:0006808)2.01671628
101Abnormal EKG (HP:0003115)1.99390110
102Epidermoid cyst (HP:0200040)1.98976243
103Termporal pattern (HP:0011008)1.97108300
104Insidious onset (HP:0003587)1.97108300
105Insomnia (HP:0100785)1.95872356
106Turricephaly (HP:0000262)1.94738985
107Abnormality of monocarboxylic acid metabolism (HP:0010996)1.93431580
108Inability to walk (HP:0002540)1.92814068
109Pigmentary retinal degeneration (HP:0001146)1.92667448
110Lower limb asymmetry (HP:0100559)1.92329006
111Gait ataxia (HP:0002066)1.90274189
112Mitral stenosis (HP:0001718)1.89703703
113Clonus (HP:0002169)1.89504120
114Abnormality of the periventricular white matter (HP:0002518)1.89048530
115Rapidly progressive (HP:0003678)1.88668992
116Stridor (HP:0010307)1.86529073
117Right ventricular cardiomyopathy (HP:0011663)1.86318187
118Delusions (HP:0000746)1.85935797
119Abnormality of saccadic eye movements (HP:0000570)1.84586413
120Neuronal loss in central nervous system (HP:0002529)1.83376582
121Shallow orbits (HP:0000586)1.82694951
122Abnormality of oral frenula (HP:0000190)1.81846780
123Increased circulating renin level (HP:0000848)1.81440413
124Hyperlipoproteinemia (HP:0010980)1.81385980
125Rigidity (HP:0002063)1.80827211
126Vascular calcification (HP:0004934)1.80381463
127Blue irides (HP:0000635)1.76500606
128Hypobetalipoproteinemia (HP:0003563)1.76183098
129Neoplasm of the heart (HP:0100544)1.75944321
130Spontaneous abortion (HP:0005268)1.73612853
131Neonatal onset (HP:0003623)1.73337628
132Limb dystonia (HP:0002451)1.73246035
133Arterial tortuosity (HP:0005116)1.72487303
134Polyphagia (HP:0002591)1.70809842
135Skin nodule (HP:0200036)1.70603927
136Spinal canal stenosis (HP:0003416)1.70463208
137Psychosis (HP:0000709)1.69973859
138Intellectual disability, profound (HP:0002187)1.67647153
139Striae distensae (HP:0001065)1.67313906
140Prolonged QT interval (HP:0001657)1.65990443
141Apathy (HP:0000741)1.65756937
142Aplasia of the phalanges of the hand (HP:0009802)1.65751488
143Aplasia involving bones of the extremities (HP:0009825)1.65751488
144Vascular tortuosity (HP:0004948)1.63784862
145Advanced eruption of teeth (HP:0006288)1.63522346
146Aneurysm (HP:0002617)1.59284830
147Menorrhagia (HP:0000132)1.57744423
148Acanthosis nigricans (HP:0000956)1.57156457
149Abnormality of the salivary glands (HP:0010286)1.57011806
150Severe Myopia (HP:0011003)1.55642684
151Anosmia (HP:0000458)1.55497654
152Syncope (HP:0001279)1.50670648
153Neonatal death (HP:0003811)1.49476958
154Ulnar claw (HP:0001178)1.48810719
155Laryngomalacia (HP:0001601)1.46305559
156Oligomenorrhea (HP:0000876)1.46239120
157Retinal atrophy (HP:0001105)1.45439452
158Urinary glycosaminoglycan excretion (HP:0003541)1.44892560
159Mucopolysacchariduria (HP:0008155)1.44892560

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.92278743
2NTRK34.45736308
3MAP3K94.01691966
4SIK13.19311998
5EPHA23.08774273
6DAPK23.06563333
7KSR22.60255873
8PRKD32.54728526
9MAP3K42.54501029
10MINK12.43419183
11MAPK152.40425248
12RIPK42.32313694
13PAK62.29974694
14FGFR42.11340517
15CAMKK12.06357011
16MAP2K72.05355828
17MARK11.95945246
18DAPK11.91450938
19NTRK11.89782256
20NTRK21.82003253
21KSR11.80113220
22ARAF1.77863230
23MAP3K131.73853742
24MAP3K121.70852723
25MAP2K41.60638679
26CDK51.59501896
27ICK1.49177778
28FES1.41597412
29MAP3K21.40974472
30ERBB21.40172880
31PLK21.39637992
32STK381.38906722
33CDK191.33193161
34TNIK1.31072040
35PRPF4B1.29678587
36TAOK11.29094843
37SIK21.28230554
38TYRO31.25926746
39EEF2K1.23524456
40GRK51.21481713
41EPHA31.17967787
42FGFR31.16744024
43WNK41.15428774
44TRIB31.14543936
45PRKCG1.13260606
46RAF11.11762475
47PTK2B1.06824173
48FGFR21.03515674
49CASK1.02411839
50CAMK11.01879374
51CAMKK21.01420032
52MAP3K31.00725462
53MAP3K60.96146205
54PRKCH0.94100879
55UHMK10.93567758
56CAMK2A0.92713637
57STK110.90572912
58CDK180.90440494
59CDK150.89353983
60PIK3CA0.88673559
61BMPR20.86898959
62MAPK130.84085137
63CDK140.83504403
64CAMK2B0.83355180
65SGK2230.80375492
66SGK4940.80375492
67PINK10.80235273
68ALK0.79845964
69MAP3K10.78731737
70RET0.78555273
71CDK11A0.77784968
72EPHB10.77345467
73PNCK0.76144890
74PDK10.75790252
75TESK10.75212799
76LATS20.74315438
77MAPKAPK30.74209965
78OXSR10.74028903
79PDPK10.73509757
80PKN10.73285436
81MAP3K110.73257402
82MARK20.72057199
83SGK10.71692062
84PAK30.70937124
85PRKAA20.70509277
86HIPK20.70074592
87RPS6KA20.66365016
88SGK30.65255285
89SGK20.64888688
90MAPK120.62701837
91MAP3K70.61950197
92LMTK20.61905192
93MAP2K60.61742970
94DAPK30.60209815
95RIPK10.59407744
96ERN10.59273954
97TNK20.59066360
98NEK60.57877464
99NEK10.57796394
100PRKAA10.56530947
101PDGFRA0.56522866
102PTK20.54043032
103FER0.52845487
104DMPK0.52734033
105JAK10.52585243
106MAP2K10.52278895
107ROCK10.52248571
108DYRK1A0.50412454
109TIE10.49952332
110PHKG20.48217016
111PHKG10.48217016
112RPS6KA30.47965985
113CHUK0.47644657
114CAMK40.46823110
115PRKCZ0.46669557
116PRKD10.46075207
117BRSK10.45241219
118FYN0.44906523
119MAPK80.44900769
120SMG10.43543584
121ROCK20.43422475
122MYLK0.43169640
123CAMK2G0.42025858
124WNK10.41537504
125PRKCE0.41352258
126MAPK100.40584977
127CAMK2D0.40427298
128FGR0.40155438
129MOS0.39729987
130CDC42BPA0.39520672
131CSNK1G20.38783722
132NME10.37082229
133BRAF0.35863078
134PRKD20.34259750
135BMX0.33139435
136CCNB10.32444132
137DDR20.32055408
138SCYL20.28890613
139PRKCB0.28304476

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.45730752
2Synaptic vesicle cycle_Homo sapiens_hsa047213.18926419
3Olfactory transduction_Homo sapiens_hsa047402.98354002
4Circadian entrainment_Homo sapiens_hsa047132.74471754
5Long-term potentiation_Homo sapiens_hsa047202.73008512
6GABAergic synapse_Homo sapiens_hsa047272.59121784
7Amphetamine addiction_Homo sapiens_hsa050312.59066210
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.53563187
9Glutamatergic synapse_Homo sapiens_hsa047242.52024807
10Morphine addiction_Homo sapiens_hsa050322.50008444
11Complement and coagulation cascades_Homo sapiens_hsa046102.26995550
12Salivary secretion_Homo sapiens_hsa049702.23568695
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.18949403
14Histidine metabolism_Homo sapiens_hsa003402.16530763
15Dopaminergic synapse_Homo sapiens_hsa047282.13278387
16Insulin secretion_Homo sapiens_hsa049111.99161830
17Gastric acid secretion_Homo sapiens_hsa049711.98736056
18Cholinergic synapse_Homo sapiens_hsa047251.94758336
19Cyanoamino acid metabolism_Homo sapiens_hsa004601.93022703
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.91402204
21Phenylalanine metabolism_Homo sapiens_hsa003601.82242973
22Cocaine addiction_Homo sapiens_hsa050301.78615482
23Oxytocin signaling pathway_Homo sapiens_hsa049211.75137888
24Renin secretion_Homo sapiens_hsa049241.71394363
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.69537415
26Calcium signaling pathway_Homo sapiens_hsa040201.64215934
27Long-term depression_Homo sapiens_hsa047301.57968242
28Taste transduction_Homo sapiens_hsa047421.55412944
29GnRH signaling pathway_Homo sapiens_hsa049121.50775100
30Vitamin B6 metabolism_Homo sapiens_hsa007501.49206616
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.48832721
32Serotonergic synapse_Homo sapiens_hsa047261.48401262
33Collecting duct acid secretion_Homo sapiens_hsa049661.37605665
34Arginine biosynthesis_Homo sapiens_hsa002201.35326778
35Gap junction_Homo sapiens_hsa045401.34681984
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.33604187
37cAMP signaling pathway_Homo sapiens_hsa040241.33603626
38Nitrogen metabolism_Homo sapiens_hsa009101.33277583
39PPAR signaling pathway_Homo sapiens_hsa033201.31060058
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29709119
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.29005119
42Glioma_Homo sapiens_hsa052141.25693719
43Caffeine metabolism_Homo sapiens_hsa002321.19031002
44Estrogen signaling pathway_Homo sapiens_hsa049151.17157986
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.16952184
46Type II diabetes mellitus_Homo sapiens_hsa049301.14821226
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.12382858
48ECM-receptor interaction_Homo sapiens_hsa045121.12313493
49Primary bile acid biosynthesis_Homo sapiens_hsa001201.10943808
50Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.07402591
51Fatty acid biosynthesis_Homo sapiens_hsa000611.06730071
52cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06025563
53Melanogenesis_Homo sapiens_hsa049161.04588135
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02398689
55ErbB signaling pathway_Homo sapiens_hsa040121.01834500
56ABC transporters_Homo sapiens_hsa020101.01393405
57beta-Alanine metabolism_Homo sapiens_hsa004101.00957370
58Arginine and proline metabolism_Homo sapiens_hsa003301.00133252
59Butanoate metabolism_Homo sapiens_hsa006500.98902612
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.96995641
61Axon guidance_Homo sapiens_hsa043600.96904020
62Tyrosine metabolism_Homo sapiens_hsa003500.94727661
63Glycosaminoglycan degradation_Homo sapiens_hsa005310.94642099
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.89642593
65Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89023506
66Vibrio cholerae infection_Homo sapiens_hsa051100.88081785
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.87536258
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.86569279
69Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.86204415
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86167551
71Fat digestion and absorption_Homo sapiens_hsa049750.85097860
72Pancreatic secretion_Homo sapiens_hsa049720.84298900
73Chemical carcinogenesis_Homo sapiens_hsa052040.84200223
74Cardiac muscle contraction_Homo sapiens_hsa042600.82523572
75Dorso-ventral axis formation_Homo sapiens_hsa043200.82082455
76Thyroid hormone synthesis_Homo sapiens_hsa049180.80753682
77Oocyte meiosis_Homo sapiens_hsa041140.80549981
78Dilated cardiomyopathy_Homo sapiens_hsa054140.79728922
79Fatty acid degradation_Homo sapiens_hsa000710.79062157
80Retinol metabolism_Homo sapiens_hsa008300.78812844
81Glycerolipid metabolism_Homo sapiens_hsa005610.75938398
82VEGF signaling pathway_Homo sapiens_hsa043700.73898821
83Choline metabolism in cancer_Homo sapiens_hsa052310.71464621
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71298498
85MAPK signaling pathway_Homo sapiens_hsa040100.69316575
86Tryptophan metabolism_Homo sapiens_hsa003800.68932439
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68858830
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68769018
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.67022944
90Notch signaling pathway_Homo sapiens_hsa043300.66824890
91Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66816327
92Rap1 signaling pathway_Homo sapiens_hsa040150.64435052
93Phototransduction_Homo sapiens_hsa047440.62082400
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60733941
95Fatty acid metabolism_Homo sapiens_hsa012120.59620905
96Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57688787
97Ras signaling pathway_Homo sapiens_hsa040140.56442658
98Glucagon signaling pathway_Homo sapiens_hsa049220.56334899
99Type I diabetes mellitus_Homo sapiens_hsa049400.55851242
100Non-small cell lung cancer_Homo sapiens_hsa052230.55764101
101Bile secretion_Homo sapiens_hsa049760.55703018
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54315411
103Glycerophospholipid metabolism_Homo sapiens_hsa005640.53259673
104Tight junction_Homo sapiens_hsa045300.52302407
105Mineral absorption_Homo sapiens_hsa049780.52147546
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.52088594
107mTOR signaling pathway_Homo sapiens_hsa041500.52025601
108AMPK signaling pathway_Homo sapiens_hsa041520.51225069
109Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50559061
110Endocytosis_Homo sapiens_hsa041440.49770970
111Steroid hormone biosynthesis_Homo sapiens_hsa001400.49228800
112Circadian rhythm_Homo sapiens_hsa047100.48972663
113Focal adhesion_Homo sapiens_hsa045100.48451903
114Alcoholism_Homo sapiens_hsa050340.47743186
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47318472
116Inositol phosphate metabolism_Homo sapiens_hsa005620.47261059
117African trypanosomiasis_Homo sapiens_hsa051430.45672531
118Prion diseases_Homo sapiens_hsa050200.45346821
119Linoleic acid metabolism_Homo sapiens_hsa005910.44683262
120Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.44076193
121Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43483218
122alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.42092122
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41598826
124Endometrial cancer_Homo sapiens_hsa052130.39627927
125Renal cell carcinoma_Homo sapiens_hsa052110.38005049
126Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.37519536
127Wnt signaling pathway_Homo sapiens_hsa043100.35858405
128Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.35686963
129Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.35373123
130Insulin signaling pathway_Homo sapiens_hsa049100.35306289
131* Chemokine signaling pathway_Homo sapiens_hsa040620.34806535
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33441998
133Ovarian steroidogenesis_Homo sapiens_hsa049130.31060020
134Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29509631
135Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.28507239
136Platelet activation_Homo sapiens_hsa046110.28044508
137Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27011678
138Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.25386353
139Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24159719

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »