CXCL13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)8.82465571
2mannose metabolic process (GO:0006013)8.55134710
3lipoxygenase pathway (GO:0019372)8.10200225
4apoptotic cell clearance (GO:0043277)7.85886385
5opsonization (GO:0008228)7.26582031
6complement activation (GO:0006956)6.82778360
7regulation of complement activation (GO:0030449)6.54722436
8regulation of protein activation cascade (GO:2000257)6.17855719
9long-chain fatty acid biosynthetic process (GO:0042759)6.11828193
10citrulline biosynthetic process (GO:0019240)5.90614359
11complement activation, classical pathway (GO:0006958)5.39818482
12detection of molecule of bacterial origin (GO:0032490)5.39277064
13negative regulation of cell killing (GO:0031342)5.30505108
14negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.30505108
15* regulation of integrin activation (GO:0033623)5.23857983
16regulation of macrophage chemotaxis (GO:0010758)5.16941718
17negative T cell selection (GO:0043383)5.09163040
18dendritic cell chemotaxis (GO:0002407)5.06523778
19protein activation cascade (GO:0072376)4.94350655
20negative thymic T cell selection (GO:0045060)4.93662654
21regulation of T-helper 1 cell differentiation (GO:0045625)4.85544063
22positive regulation of gamma-delta T cell activation (GO:0046645)4.77683530
23regulation of dendritic cell antigen processing and presentation (GO:0002604)4.75396257
24leukotriene metabolic process (GO:0006691)4.68288370
25T cell costimulation (GO:0031295)4.65513512
26negative regulation of granulocyte differentiation (GO:0030853)4.63022790
27lymphocyte costimulation (GO:0031294)4.58939735
28activated T cell proliferation (GO:0050798)4.54206419
29positive regulation of neutrophil migration (GO:1902624)4.51832432
30positive regulation of neutrophil chemotaxis (GO:0090023)4.51832432
31regulation of cellular extravasation (GO:0002691)4.48804761
32positive regulation of glycoprotein biosynthetic process (GO:0010560)4.48272361
33production of molecular mediator involved in inflammatory response (GO:0002532)4.45693078
34NIK/NF-kappaB signaling (GO:0038061)4.44550779
35response to interleukin-15 (GO:0070672)4.43519826
36negative regulation of interleukin-12 production (GO:0032695)4.40833947
37antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.38343309
38regulation of regulatory T cell differentiation (GO:0045589)4.37407668
39positive regulation of pseudopodium assembly (GO:0031274)4.34166373
40positive thymic T cell selection (GO:0045059)4.32895534
41thymic T cell selection (GO:0045061)4.32691564
42* regulation of humoral immune response (GO:0002920)4.26632602
43positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.25946439
44fatty acid derivative biosynthetic process (GO:1901570)4.23862806
45icosanoid biosynthetic process (GO:0046456)4.23862806
46response to prostaglandin E (GO:0034695)4.21467395
47cellular extravasation (GO:0045123)4.19689511
48regulation of T cell tolerance induction (GO:0002664)4.19491998
49positive regulation of granulocyte chemotaxis (GO:0071624)4.19281433
50positive regulation of respiratory burst (GO:0060267)4.18818571
51T cell selection (GO:0045058)4.16436287
52regulation of phagocytosis (GO:0050764)4.14801906
53regulation of gamma-delta T cell differentiation (GO:0045586)4.14401043
54myeloid dendritic cell differentiation (GO:0043011)4.08429080
55response to type I interferon (GO:0034340)4.01849342
56interferon-gamma-mediated signaling pathway (GO:0060333)3.99088726
57dendritic cell migration (GO:0036336)3.98476178
58type I interferon signaling pathway (GO:0060337)3.97471160
59cellular response to type I interferon (GO:0071357)3.97471160
60positive regulation of glycoprotein metabolic process (GO:1903020)3.94280427
61positive T cell selection (GO:0043368)3.93161675
62cellular response to interleukin-15 (GO:0071350)3.92314865
63regulation of pseudopodium assembly (GO:0031272)3.88816858
64peptidyl-glutamic acid carboxylation (GO:0017187)3.82480034
65protein carboxylation (GO:0018214)3.82480034
66cyclooxygenase pathway (GO:0019371)3.82234903
67regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.81818647
68leukocyte tethering or rolling (GO:0050901)3.78438288
69phosphatidylethanolamine biosynthetic process (GO:0006646)3.78042352
70myeloid dendritic cell activation (GO:0001773)3.76281109
71citrulline metabolic process (GO:0000052)3.72748928
72tolerance induction (GO:0002507)3.71120585
73detection of external biotic stimulus (GO:0098581)3.67451851
74cytokine production involved in immune response (GO:0002367)3.67091220
75regulation of gamma-delta T cell activation (GO:0046643)3.64736639
76immunoglobulin mediated immune response (GO:0016064)3.62246343
77positive regulation of tolerance induction (GO:0002645)3.61137294
78unsaturated fatty acid biosynthetic process (GO:0006636)3.59944404
79positive regulation of antigen processing and presentation (GO:0002579)3.56604837
80regulation of interleukin-2 biosynthetic process (GO:0045076)3.55671543
81positive regulation of blood coagulation (GO:0030194)3.52770736
82positive regulation of hemostasis (GO:1900048)3.52770736
83arachidonic acid metabolic process (GO:0019369)3.49105168
84detection of biotic stimulus (GO:0009595)3.47825249
85phosphatidylethanolamine metabolic process (GO:0046337)3.46904432
86response to nitric oxide (GO:0071731)3.41487823
87regulation of tolerance induction (GO:0002643)3.41289073
88regulation of mononuclear cell migration (GO:0071675)3.39440334
89respiratory burst (GO:0045730)3.37162032
90positive regulation of coagulation (GO:0050820)3.35312144
91regulation of respiratory burst (GO:0060263)3.33605966
92detection of bacterium (GO:0016045)3.33408017
93positive regulation of Cdc42 GTPase activity (GO:0043089)3.30338748
94prostaglandin biosynthetic process (GO:0001516)3.29543124
95prostanoid biosynthetic process (GO:0046457)3.29543124
96positive regulation of phagocytosis (GO:0050766)3.29381329
97T cell mediated immunity (GO:0002456)3.29129460
98dendritic cell differentiation (GO:0097028)3.25490335
99leukocyte migration involved in inflammatory response (GO:0002523)3.24083206
100oxygen transport (GO:0015671)3.23807424
101production of molecular mediator of immune response (GO:0002440)3.23148375
102positive regulation of cholesterol efflux (GO:0010875)3.22106253
103immune response-activating cell surface receptor signaling pathway (GO:0002429)3.20998913
104positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.19957742
105regulation of neutrophil migration (GO:1902622)3.19901045
106regulation of neutrophil chemotaxis (GO:0090022)3.19901045
107regulation of alpha-beta T cell proliferation (GO:0046640)3.19809036
108regulation of antigen processing and presentation (GO:0002577)3.19226193
109regulation of cholesterol storage (GO:0010885)3.18490730
110T cell receptor signaling pathway (GO:0050852)3.18311211
111antigen receptor-mediated signaling pathway (GO:0050851)3.18306056
112B cell receptor signaling pathway (GO:0050853)3.17264140
113glomerular filtration (GO:0003094)3.16264907
114positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.16251340
115sequestering of extracellular ligand from receptor (GO:0035581)3.13755917
116response to prostaglandin (GO:0034694)3.13707212
117phagocytosis (GO:0006909)3.12923627
118cellular response to interferon-gamma (GO:0071346)3.11193715
119detection of other organism (GO:0098543)3.11165046
120antigen processing and presentation of endogenous antigen (GO:0019883)3.09942203
121negative regulation of interleukin-6 production (GO:0032715)3.08913469
122positive regulation of B cell differentiation (GO:0045579)3.06975134
123* positive regulation of lymphocyte migration (GO:2000403)3.06685602
124positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.05961528
125positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.05099315
126regulation of B cell receptor signaling pathway (GO:0050855)3.02429508
127regulation of type I interferon-mediated signaling pathway (GO:0060338)3.00914717
128positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.00313050
129negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.98804256
130humoral immune response (GO:0006959)2.97506195
131B cell mediated immunity (GO:0019724)2.97221772
132phospholipid efflux (GO:0033700)2.95888300
133regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.95879817
134regulation of natural killer cell mediated immunity (GO:0002715)2.95879817
135antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.95079182
136antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.95079182
137antigen processing and presentation via MHC class Ib (GO:0002475)2.94638997
138positive regulation of sterol transport (GO:0032373)2.94559747
139positive regulation of cholesterol transport (GO:0032376)2.94559747
140cGMP-mediated signaling (GO:0019934)2.94397804
141response to interferon-gamma (GO:0034341)2.94229801
142negative regulation of interleukin-2 production (GO:0032703)2.93881222
143positive regulation of immunoglobulin production (GO:0002639)2.93258448
144regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.92493495
145regulation of granulocyte chemotaxis (GO:0071622)2.92360891
146leukocyte cell-cell adhesion (GO:0007159)2.90472883
147adaptation of signaling pathway (GO:0023058)2.89242977
148antimicrobial humoral response (GO:0019730)2.87533432
149immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:00022.86987380
150Fc-gamma receptor signaling pathway (GO:0038094)2.86987380
151Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)2.86987380
152prostanoid metabolic process (GO:0006692)2.86953081
153prostaglandin metabolic process (GO:0006693)2.86953081
154Fc receptor mediated stimulatory signaling pathway (GO:0002431)2.85562907
155B cell proliferation (GO:0042100)2.85458701
156regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.85382320
157cardiac epithelial to mesenchymal transition (GO:0060317)2.85311268
158plasma lipoprotein particle clearance (GO:0034381)2.83971476
159leukocyte aggregation (GO:0070486)2.83739083
160negative regulation of erythrocyte differentiation (GO:0045647)2.83053149
161response to interferon-beta (GO:0035456)2.82216021
162regulation of B cell differentiation (GO:0045577)2.81572624
163regulation of isotype switching to IgG isotypes (GO:0048302)2.81105883
164regulation of transforming growth factor beta2 production (GO:0032909)2.79326438
165* positive regulation of T cell migration (GO:2000406)2.79128018
166angiotensin maturation (GO:0002003)2.78713614
167negative regulation of macrophage differentiation (GO:0045650)2.78036571
168regulation of macrophage cytokine production (GO:0010935)2.71690699
169negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.70570717
170cytoskeletal anchoring at plasma membrane (GO:0007016)2.70135503
171low-density lipoprotein particle clearance (GO:0034383)2.69228108
172cellular response to interleukin-6 (GO:0071354)2.67511735
173modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.66385317
174positive regulation by organism of defense response of other organism involved in symbiotic interact2.66385317
175modulation by symbiont of host immune response (GO:0052553)2.66385317
176positive regulation by symbiont of host defense response (GO:0052509)2.66385317
177modulation by symbiont of host defense response (GO:0052031)2.66385317
178modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.66385317
179urea metabolic process (GO:0019627)2.63690129
180urea cycle (GO:0000050)2.63690129
181leukotriene biosynthetic process (GO:0019370)2.63637148
182fatty acid derivative metabolic process (GO:1901568)2.61131505
183icosanoid metabolic process (GO:0006690)2.61131505
184acute-phase response (GO:0006953)2.59692224
185regulation of apoptotic cell clearance (GO:2000425)12.8985731
186complement activation, alternative pathway (GO:0006957)10.4486093

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.14264198
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.03558573
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.93079976
4THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.89195740
5NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.99439608
6RXR_22158963_ChIP-Seq_LIVER_Mouse2.94412735
7IRF8_27001747_Chip-Seq_BMDM_Mouse2.91303536
8SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.86001296
9STAT4_19710469_ChIP-ChIP_TH1__Mouse2.83031819
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.56993874
11MYB_26560356_Chip-Seq_TH2_Human2.56673409
12PPARA_22158963_ChIP-Seq_LIVER_Mouse2.53355486
13PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.49971722
14RARG_19884340_ChIP-ChIP_MEFs_Mouse2.42364352
15Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.18399486
16LXR_22158963_ChIP-Seq_LIVER_Mouse2.18350053
17NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.18042469
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.10213747
19MYB_21317192_ChIP-Seq_ERMYB_Mouse2.06436695
20MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.03562896
21IRF8_22096565_ChIP-ChIP_GC-B_Human2.02510962
22SMAD_19615063_ChIP-ChIP_OVARY_Human2.00432158
23MYB_26560356_Chip-Seq_TH1_Human1.95846131
24RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.90415200
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.87331804
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.84309699
27LXR_22292898_ChIP-Seq_THP-1_Human1.84292453
28IKZF1_21737484_ChIP-ChIP_HCT116_Human1.74103820
29STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.72586009
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.70687699
31EGR1_19374776_ChIP-ChIP_THP-1_Human1.66778821
32SPI1_23127762_ChIP-Seq_K562_Human1.66071232
33BRD4_27068464_Chip-Seq_AML-cells_Mouse1.60016240
34ELK3_25401928_ChIP-Seq_HUVEC_Human1.56344994
35EGR1_23403033_ChIP-Seq_LIVER_Mouse1.55335774
36VDR_24763502_ChIP-Seq_THP-1_Human1.54159065
37FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.50774985
38TP63_17297297_ChIP-ChIP_HaCaT_Human1.50672114
39SCL_19346495_ChIP-Seq_HPC-7_Human1.50148666
40IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.49676487
41MAF_26560356_Chip-Seq_TH2_Human1.49469256
42E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.47573971
43RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.46603312
44NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.46351588
45KDM2B_26808549_Chip-Seq_SUP-B15_Human1.45706937
46SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.44472954
47VDR_21846776_ChIP-Seq_THP-1_Human1.44185342
48GATA3_27048872_Chip-Seq_THYMUS_Human1.42151952
49STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.41268934
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39506269
51TRIM28_21343339_ChIP-Seq_HEK293_Human1.37100304
52VDR_24787735_ChIP-Seq_THP-1_Human1.36051837
53TCF7_22412390_ChIP-Seq_EML_Mouse1.35343611
54CLOCK_20551151_ChIP-Seq_293T_Human1.34587604
55CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.31358302
56BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.30954100
57GATA2_21666600_ChIP-Seq_HMVEC_Human1.29170688
58STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.28010380
59TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.27959411
60FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.24385219
61RACK7_27058665_Chip-Seq_MCF-7_Human1.24207638
62GATA1_19941827_ChIP-Seq_MEL_Mouse1.23871164
63MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.23048566
64GATA2_19941826_ChIP-Seq_K562_Human1.22572838
65SPI1_20517297_ChIP-Seq_HL60_Human1.19077993
66GATA3_26560356_Chip-Seq_TH2_Human1.14632128
67RUNX_20019798_ChIP-Seq_JUKART_Human1.14099578
68PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.13625827
69KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.13257154
70PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13091561
71KDM2B_26808549_Chip-Seq_DND41_Human1.11723588
72TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.10040191
73LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.09778084
74CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09602413
75KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.09393541
76GATA1_22025678_ChIP-Seq_K562_Human1.08529873
77GATA2_22383799_ChIP-Seq_G1ME_Mouse1.06960154
78LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.06890695
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.05856024
80PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04670952
81ESR2_21235772_ChIP-Seq_MCF-7_Human1.04123911
82GATA1_19941826_ChIP-Seq_K562_Human1.03824123
83EGR1_19032775_ChIP-ChIP_M12_Human1.03410272
84CDX2_20551321_ChIP-Seq_CACO-2_Human1.03196821
85SPI1_23547873_ChIP-Seq_NB4_Human1.02763910
86MAF_26560356_Chip-Seq_TH1_Human1.02396665
87CIITA_25753668_ChIP-Seq_RAJI_Human1.01174683
88RUNX1_22412390_ChIP-Seq_EML_Mouse1.00714015
89PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00525184
90CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99953926
91GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99926055
92ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.98605508
93CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97084019
94RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.96291105
95STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.95575487
96SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94593104
97MYC_22102868_ChIP-Seq_BL_Human0.94205025
98SOX2_20726797_ChIP-Seq_SW620_Human0.94099535
99IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.93669681
100GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93429482
101KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92290478
102SOX2_27498859_Chip-Seq_STOMACH_Mouse0.91071969
103ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90945401
104GATA1_22383799_ChIP-Seq_G1ME_Mouse0.90376610
105NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.90253097
106ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.90149852
107FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.89070603
108GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88967562
109BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.88652942
110SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88431251
111ERG_21242973_ChIP-ChIP_JURKAT_Human0.88145474
112FOXA2_19822575_ChIP-Seq_HepG2_Human0.87963528
113TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.86754012
114NFIB_24661679_ChIP-Seq_LUNG_Mouse0.86648846
115PU.1_20513432_ChIP-Seq_Bcells_Mouse0.86353769
116PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.85267100
117UTX_26944678_Chip-Seq_JUKART_Human0.84797279
118PU_27001747_Chip-Seq_BMDM_Mouse0.84643807
119TDRD3_21172665_ChIP-Seq_MCF-7_Human0.84487882
120FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84394886
121P63_26484246_Chip-Seq_KERATINOCYTES_Human0.83174539
122SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.82997085
123CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.82943130
124FOXO3_23340844_ChIP-Seq_DLD1_Human0.82850251
125FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.82486314
126CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.81035367
127BCL6_27268052_Chip-Seq_Bcells_Human0.78232590
128BCOR_27268052_Chip-Seq_Bcells_Human0.76734287
129STAT1_20625510_ChIP-Seq_HELA_Human0.74384902
130FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.73756607
131SA1_27219007_Chip-Seq_Bcells_Human0.72978736
132SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.71201053

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to3.87494290
2MP0009840_abnormal_foam_cell3.69353707
3MP0005058_abnormal_lysosome_morphology3.61434437
4MP0003724_increased_susceptibility_to3.56016505
5MP0003763_abnormal_thymus_physiology3.53403345
6MP0003436_decreased_susceptibility_to3.39709607
7MP0003705_abnormal_hypodermis_morpholog3.29579229
8MP0001790_abnormal_immune_system3.04175860
9MP0005387_immune_system_phenotype3.04175860
10MP0008438_abnormal_cutaneous_collagen3.03910731
11MP0000685_abnormal_immune_system2.97895950
12MP0003191_abnormal_cellular_cholesterol2.87698869
13MP0010155_abnormal_intestine_physiology2.77764048
14MP0003303_peritoneal_inflammation2.65046751
15MP0003075_altered_response_to2.59561819
16MP0005025_abnormal_response_to2.51277032
17MP0001533_abnormal_skeleton_physiology2.45808097
18MP0002419_abnormal_innate_immunity2.45750235
19MP0002254_reproductive_system_inflammat2.41628056
20MP0009333_abnormal_splenocyte_physiolog2.34383140
21MP0002138_abnormal_hepatobiliary_system2.32160962
22MP0005000_abnormal_immune_tolerance2.23517351
23MP0004947_skin_inflammation2.19119844
24MP0003866_abnormal_defecation2.17893136
25MP0002148_abnormal_hypersensitivity_rea2.15546709
26MP0001851_eye_inflammation2.07855671
27MP0001835_abnormal_antigen_presentation2.07318704
28MP0005464_abnormal_platelet_physiology1.89485820
29MP0001853_heart_inflammation1.88702144
30MP0001800_abnormal_humoral_immune1.82100922
31MP0000604_amyloidosis1.81379810
32MP0004510_myositis1.75016324
33MP0008004_abnormal_stomach_pH1.62605994
34MP0005023_abnormal_wound_healing1.59965999
35MP0002166_altered_tumor_susceptibility1.57160739
36* MP0002452_abnormal_antigen_presenting1.56401395
37MP0010352_gastrointestinal_tract_polyps1.55736921
38MP0010368_abnormal_lymphatic_system1.54502261
39MP0002405_respiratory_system_inflammati1.53851156
40MP0000767_abnormal_smooth_muscle1.49906841
41MP0003300_gastrointestinal_ulcer1.48200701
42MP0003566_abnormal_cell_adhesion1.48144408
43MP0001845_abnormal_inflammatory_respons1.45424691
44MP0009763_increased_sensitivity_to1.43329441
45MP0005360_urolithiasis1.43191055
46MP0000249_abnormal_blood_vessel1.40221907
47MP0009785_altered_susceptibility_to1.39534420
48MP0000703_abnormal_thymus_morphology1.39196930
49MP0001849_ear_inflammation1.38252871
50MP0010329_abnormal_lipoprotein_level1.37290119
51MP0002909_abnormal_adrenal_gland1.35303243
52MP0004272_abnormal_basement_membrane1.33312498
53* MP0002420_abnormal_adaptive_immunity1.32720585
54* MP0001819_abnormal_immune_cell1.30635231
55MP0002933_joint_inflammation1.29611011
56MP0002723_abnormal_immune_serum1.29023145
57MP0004885_abnormal_endolymph1.27511543
58MP0005390_skeleton_phenotype1.23767592
59MP0001666_abnormal_nutrient_absorption1.23637639
60MP0000343_altered_response_to1.23362060
61MP0002139_abnormal_hepatobiliary_system1.22964825
62MP0005451_abnormal_body_composition1.22432777
63MP0005166_decreased_susceptibility_to1.20022518
64MP0003690_abnormal_glial_cell1.18012216
65MP0003656_abnormal_erythrocyte_physiolo1.16306836
66MP0008469_abnormal_protein_level1.16087579
67MP0003878_abnormal_ear_physiology1.12942142
68MP0005377_hearing/vestibular/ear_phenot1.12942142
69MP0006082_CNS_inflammation1.12011706
70MP0002168_other_aberrant_phenotype1.11970278
71MP0001663_abnormal_digestive_system1.10999113
72MP0009764_decreased_sensitivity_to1.09551309
73MP0003172_abnormal_lysosome_physiology1.07824801
74MP0005670_abnormal_white_adipose1.07250699
75MP0008875_abnormal_xenobiotic_pharmacok1.06314985
76MP0005332_abnormal_amino_acid1.05345745
77MP0004185_abnormal_adipocyte_glucose1.04485926
78MP0005365_abnormal_bile_salt1.03914161
79MP0003183_abnormal_peptide_metabolism1.03047740
80* MP0000716_abnormal_immune_system1.02426270
81MP0002136_abnormal_kidney_physiology1.02420630
82MP0001915_intracranial_hemorrhage1.00526494
83MP0000609_abnormal_liver_physiology0.98354472
84MP0002277_abnormal_respiratory_mucosa0.98224350
85MP0003638_abnormal_response/metabolism_0.97565854
86MP0000490_abnormal_crypts_of0.96613717
87MP0003448_altered_tumor_morphology0.93885575
88MP0002998_abnormal_bone_remodeling0.93561835
89MP0004264_abnormal_extraembryonic_tissu0.92589853
90MP0000465_gastrointestinal_hemorrhage0.90988955
91MP0001873_stomach_inflammation0.90948725
92MP0002006_tumorigenesis0.90443686
93MP0002118_abnormal_lipid_homeostasis0.89876592
94MP0004782_abnormal_surfactant_physiolog0.89802507
95* MP0000689_abnormal_spleen_morphology0.89686526
96MP0003453_abnormal_keratinocyte_physiol0.86825013
97MP0000858_altered_metastatic_potential0.86075166
98MP0002282_abnormal_trachea_morphology0.85644473
99MP0009643_abnormal_urine_homeostasis0.83612029
100MP0002396_abnormal_hematopoietic_system0.83592943
101MP0005085_abnormal_gallbladder_physiolo0.82713960
102MP0000477_abnormal_intestine_morphology0.82542012
103MP0002429_abnormal_blood_cell0.82140912
104MP0002135_abnormal_kidney_morphology0.79743075
105MP0003329_amyloid_beta_deposits0.79551214
106MP0005310_abnormal_salivary_gland0.79334045
107MP0003045_fibrosis0.78287592
108MP0002971_abnormal_brown_adipose0.77968314
109MP0003868_abnormal_feces_composition0.76758965
110MP0009278_abnormal_bone_marrow0.75020628
111MP0003091_abnormal_cell_migration0.74132079
112MP0001614_abnormal_blood_vessel0.74063971
113MP0005381_digestive/alimentary_phenotyp0.73750593
114MP0005584_abnormal_enzyme/coenzyme_acti0.73412243
115MP0002060_abnormal_skin_morphology0.73244841
116MP0002398_abnormal_bone_marrow0.72963002
117MP0005165_increased_susceptibility_to0.72808406
118* MP0002722_abnormal_immune_system0.70872824
119MP0000598_abnormal_liver_morphology0.69378797
120MP0005083_abnormal_biliary_tract0.68993953
121MP0004019_abnormal_vitamin_homeostasis0.68455982
122MP0010234_abnormal_vibrissa_follicle0.68081966
123MP0002796_impaired_skin_barrier0.64495122
124MP0001348_abnormal_lacrimal_gland0.63972816
125MP0003252_abnormal_bile_duct0.62625793
126MP0003279_aneurysm0.61162055
127MP0009379_abnormal_foot_pigmentation0.58520044
128MP0009765_abnormal_xenobiotic_induced0.58098737
129MP0001216_abnormal_epidermal_layer0.55009824
130MP0002693_abnormal_pancreas_physiology0.52684839
131MP0005275_abnormal_skin_tensile0.50167256
132MP0003795_abnormal_bone_structure0.50085776
133MP0002009_preneoplasia0.48471279

Predicted human phenotypes

RankGene SetZ-score
1Glomerulonephritis (HP:0000099)8.08630024
2Complement deficiency (HP:0004431)7.65096535
3Abnormality of complement system (HP:0005339)7.62977478
4Chronic diarrhea (HP:0002028)6.24133474
5Gastrointestinal stroma tumor (HP:0100723)6.04287554
6Recurrent gram-negative bacterial infections (HP:0005420)5.42911901
7Dysostosis multiplex (HP:0000943)5.04235576
8Vasculitis (HP:0002633)4.86763244
9Shallow orbits (HP:0000586)4.83797380
10Vacuolated lymphocytes (HP:0001922)4.79516698
11Nephritis (HP:0000123)4.73897649
12Recurrent bronchitis (HP:0002837)4.72744575
13Spondylolisthesis (HP:0003302)4.60420016
14Abnormal delayed hypersensitivity skin test (HP:0002963)4.57987728
15Deep venous thrombosis (HP:0002625)4.39193283
16Emphysema (HP:0002097)4.37633770
17Nasal polyposis (HP:0100582)4.23133212
18IgA deficiency (HP:0002720)4.18096358
19Abnormality of cells of the lymphoid lineage (HP:0012140)4.10678933
20Eczematoid dermatitis (HP:0000976)4.06965417
21Agammaglobulinemia (HP:0004432)4.02736018
22Mucopolysacchariduria (HP:0008155)4.00576257
23Urinary glycosaminoglycan excretion (HP:0003541)4.00576257
24Abnormality of the nasal mucosa (HP:0000433)3.94994314
25Asymmetric septal hypertrophy (HP:0001670)3.93553984
26Cervical subluxation (HP:0003308)3.91427799
27Recurrent abscess formation (HP:0002722)3.90432183
28Lymphopenia (HP:0001888)3.90318617
29Abnormality of the prostate (HP:0008775)3.86995667
30Pulmonary infiltrates (HP:0002113)3.86560858
31Meningitis (HP:0001287)3.82759011
32Pustule (HP:0200039)3.77852358
33Malnutrition (HP:0004395)3.74730988
34Abnormality of mucopolysaccharide metabolism (HP:0011020)3.72424423
35Abnormality of polysaccharide metabolism (HP:0011012)3.72424423
36Abnormality of glycosaminoglycan metabolism (HP:0004371)3.72424423
37Panhypogammaglobulinemia (HP:0003139)3.67056118
38Wrist flexion contracture (HP:0001239)3.63935174
39Loss of speech (HP:0002371)3.62123415
40Elevated erythrocyte sedimentation rate (HP:0003565)3.57861388
41Peritonitis (HP:0002586)3.53064934
42Abnormality of T cell number (HP:0011839)3.48051087
43J-shaped sella turcica (HP:0002680)3.47819432
44T lymphocytopenia (HP:0005403)3.47493926
45Prolonged partial thromboplastin time (HP:0003645)3.37562105
46Abnormality of T cells (HP:0002843)3.36511225
47Obstructive lung disease (HP:0006536)3.36195761
48Chronic obstructive pulmonary disease (HP:0006510)3.36195761
49Joint stiffness (HP:0001387)3.32706335
50Cerebral aneurysm (HP:0004944)3.32051919
51Recurrent viral infections (HP:0004429)3.30590691
52Hemoptysis (HP:0002105)3.24883411
53Recurrent sinusitis (HP:0011108)3.21909143
54Abnormality of T cell physiology (HP:0011840)3.20223503
55Abnormality of the common coagulation pathway (HP:0010990)3.14683632
56Menorrhagia (HP:0000132)3.09761041
57Recurrent bacterial skin infections (HP:0005406)3.08922413
58Arthropathy (HP:0003040)3.07236582
59Bronchomalacia (HP:0002780)3.05413401
60Myositis (HP:0100614)3.04632342
61Increased IgE level (HP:0003212)2.98459110
62Autoimmune hemolytic anemia (HP:0001890)2.97235777
63Abnormality of B cell number (HP:0010975)2.95433353
64IgG deficiency (HP:0004315)2.95423060
65Chronic otitis media (HP:0000389)2.93422548
66Colitis (HP:0002583)2.92626913
67B lymphocytopenia (HP:0010976)2.88569034
68IgM deficiency (HP:0002850)2.86608617
69Increased IgM level (HP:0003496)2.84768084
70Prostate neoplasm (HP:0100787)2.81903734
71Inflammation of the large intestine (HP:0002037)2.78971116
72Pulmonary embolism (HP:0002204)2.78124411
73Encephalitis (HP:0002383)2.75969196
74Arterial tortuosity (HP:0005116)2.75761586
75Chest pain (HP:0100749)2.73036302
76Short nail (HP:0001799)2.72809970
77Abnormality of the lumbar spine (HP:0100712)2.71574731
78Gastrointestinal infarctions (HP:0005244)2.71273173
79Orchitis (HP:0100796)2.67022310
80Gastrointestinal inflammation (HP:0004386)2.66121593
81Gangrene (HP:0100758)2.64071581
82Bronchitis (HP:0012387)2.63849812
83Skin rash (HP:0000988)2.61926377
84Abnormality of macrophages (HP:0004311)2.61006541
85Broad metatarsal (HP:0001783)2.60303275
86Retrobulbar optic neuritis (HP:0100654)2.59659783
87Optic neuritis (HP:0100653)2.59659783
88Deformed sella turcica (HP:0002681)2.56878834
89Esophageal varix (HP:0002040)2.53412085
90Joint hemorrhage (HP:0005261)2.48984513
91Joint swelling (HP:0001386)2.46679121
92Thoracic kyphosis (HP:0002942)2.46603926
93Hypergammaglobulinemia (HP:0010702)2.46426801
94Spontaneous hematomas (HP:0007420)2.45495250
95Gingivitis (HP:0000230)2.45277317
96Lymphoma (HP:0002665)2.42948394
97Vascular tortuosity (HP:0004948)2.42212810
98Hand muscle atrophy (HP:0009130)2.38321411
99Prolonged bleeding time (HP:0003010)2.37893493
100Abnormality of glutamine family amino acid metabolism (HP:0010902)2.36837408
101Premature loss of primary teeth (HP:0006323)2.36483286
102Enlarged penis (HP:0000040)2.36337759
103Interstitial pulmonary disease (HP:0006530)2.32790953
104Periodontitis (HP:0000704)2.31531436
105Arthralgia (HP:0002829)2.29838697
106Verrucae (HP:0200043)2.29672315
107Papilloma (HP:0012740)2.29672315
108Polygenic inheritance (HP:0010982)2.28634091
109Ileus (HP:0002595)2.28529987
110Stomatitis (HP:0010280)2.28475262
111Abnormality of the pleura (HP:0002103)2.26118569
112Abnormality of the fingertips (HP:0001211)2.24462355
113Multifactorial inheritance (HP:0001426)2.22093373
114Abnormality of male internal genitalia (HP:0000022)2.18878034
115Abnormality of small intestinal villus morphology (HP:0011472)2.18106894
116Villous atrophy (HP:0011473)2.18106894
117Glomerulopathy (HP:0100820)2.15939688
118Toxemia of pregnancy (HP:0100603)2.15751372
119Leukocytosis (HP:0001974)2.13537894
120Beaking of vertebral bodies (HP:0004568)2.12070378
121Turricephaly (HP:0000262)2.11757813
122Recurrent skin infections (HP:0001581)2.11165589
123Osteomyelitis (HP:0002754)2.10127602
124Ovoid vertebral bodies (HP:0003300)2.09994677
125Congenital malformation of the right heart (HP:0011723)2.08554452
126Double outlet right ventricle (HP:0001719)2.08554452
127Neurofibrillary tangles (HP:0002185)2.08475154
128Ureteral stenosis (HP:0000071)2.07048884
129Severe combined immunodeficiency (HP:0004430)2.06514328
130Hematochezia (HP:0002573)2.05545668
131Systemic lupus erythematosus (HP:0002725)11.8635193
132Increased cerebral lipofuscin (HP:0011813)1.98467483
133Coarse hair (HP:0002208)1.96562341
134Keratoconjunctivitis sicca (HP:0001097)1.96457798
135Chronic sinusitis (HP:0011109)1.96455293
136Cellulitis (HP:0100658)1.95807697
137Mitral stenosis (HP:0001718)1.94701491
138Recurrent fungal infections (HP:0002841)1.94058770
139Epistaxis (HP:0000421)1.93827585
140Flat acetabular roof (HP:0003180)1.93408221
141Skin ulcer (HP:0200042)1.93136782
142Urticaria (HP:0001025)1.92000289
143Upper limb amyotrophy (HP:0009129)1.91534313
144Distal upper limb amyotrophy (HP:0007149)1.91534313
145Pulmonary fibrosis (HP:0002206)1.89927859
146Eosinophilia (HP:0001880)1.89102761
147Neonatal hypoglycemia (HP:0001998)1.89006719
148Granulocytopenia (HP:0001913)1.88755640
149Xanthomatosis (HP:0000991)1.85551017
150Mediastinal lymphadenopathy (HP:0100721)1.81118540
151Facial diplegia (HP:0001349)1.78468711
152Increased neuronal autofluorescent lipopigment (HP:0002074)1.76903256
153Broad face (HP:0000283)1.75094423
154Thickened calvaria (HP:0002684)1.73602879
155Abnormality of the sella turcica (HP:0002679)1.72668683
156Cerebral inclusion bodies (HP:0100314)1.72153826
157Abnormality of the thoracic spine (HP:0100711)1.71105467
158Hypoplasia of the odontoid process (HP:0003311)1.68722818
159Purpura (HP:0000979)1.63502457
160Gingival bleeding (HP:0000225)1.61511642
161Pathologic fracture (HP:0002756)1.59541639
162Amyloidosis (HP:0011034)1.58532294
163Osteolytic defects of the hand bones (HP:0009699)1.58087557
164Osteolytic defects of the phalanges of the hand (HP:0009771)1.58087557
165Ulnar deviation of the wrist (HP:0003049)1.57824341
166Disinhibition (HP:0000734)1.56559485
167Severe short stature (HP:0003510)1.56511418
168Recurrent cutaneous fungal infections (HP:0011370)1.55851986
169Chronic mucocutaneous candidiasis (HP:0002728)1.55851986
170Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.54935983
171Vertebral hypoplasia (HP:0008417)1.54935983
172Restrictive lung disease (HP:0002091)1.54334986
173Synostosis involving the elbow (HP:0003938)1.53593826
174Humeroradial synostosis (HP:0003041)1.53593826
175Aortic dissection (HP:0002647)1.51893524

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R7.57106588
2TXK5.14132332
3ERN13.95873895
4MET3.33809556
5CAMK1D3.33667261
6TRIB33.01415561
7DAPK22.98530555
8BLK2.96810862
9PRPF4B2.92288045
10MAP4K12.58576149
11CAMK1G2.55183461
12EPHB12.42733025
13RIPK12.40842589
14TESK12.38041043
15TAOK32.36886940
16TYK22.02731173
17BMX2.01684365
18TGFBR21.90011302
19ITK1.77202088
20PTK61.74517579
21PKN21.71596412
22PASK1.69306309
23TNK21.57467463
24SMG11.55149890
25EPHA31.43518478
26EPHB21.42314910
27MAP3K111.40414527
28FES1.39136051
29LRRK21.32925150
30ZAP701.32679667
31GRK61.30958985
32MAP3K131.30639193
33TTN1.29227198
34IRAK41.28877636
35BMPR21.27505393
36HCK1.23675648
37PRKCH1.21953489
38STK101.21084990
39TBK11.18653562
40FGR1.16621748
41CSK1.14926107
42HIPK21.13937609
43FGFR41.13813560
44MAP2K31.06577565
45MST41.04869634
46KIT1.00332863
47SIK30.98838854
48MAP3K140.97657239
49JAK30.93766167
50JAK10.92566519
51DAPK10.92245681
52PRKCQ0.91669171
53ACVR1B0.91605610
54CAMKK20.90359177
55CAMKK10.89304222
56CDC42BPA0.87539182
57IRAK10.85998851
58NTRK10.85485497
59CLK10.83197466
60IGF1R0.79363272
61BTK0.78607279
62MAP3K70.76759786
63EPHA20.76201080
64MAPK110.75716337
65SIK20.73284169
66EEF2K0.71581425
67JAK20.69683743
68RIPK40.69540156
69NLK0.68982007
70DAPK30.66124688
71IKBKE0.64941687
72FER0.64857829
73MAP3K10.63674470
74RPS6KA40.62810983
75STK380.62289101
76MAP3K60.60964462
77SYK0.60604879
78LCK0.58739821
79PDGFRB0.58567529
80EGFR0.56831092
81CSF1R0.56241408
82RPS6KA20.55123488
83MARK30.53626156
84MAPK120.53420626
85MAPK70.53131998
86TEC0.51934911
87KDR0.51160745
88CHUK0.50919339
89PRKAA20.50587600
90FYN0.48367904
91GRK70.48094550
92PTK20.48072165
93MAP3K30.46502969
94PDPK10.46371674
95FGFR10.45586550
96MATK0.45286673
97PRKG20.43764993
98FGFR30.43086033
99DMPK0.42801769
100TYRO30.42091305
101FLT30.41050175
102MELK0.40071302
103GRK50.39924992
104TGFBR10.39736302
105SIK10.39421574
106IKBKB0.39088766
107PIM10.37460833
108RPS6KL10.36936727
109RPS6KC10.36936727
110RPS6KA60.36929706
111MAP2K40.36374218
112SCYL20.33313505
113INSR0.33230723
114PTK2B0.32483238
115CAMK10.31592654
116NEK90.31107698
117TAOK10.30134634
118MAP2K20.29964694
119MAP3K100.29930921
120RET0.29450448
121ALK0.29280210
122PRKCD0.29032086
123PKN10.28064848
124INSRR0.27572296
125MYLK0.26878873
126MAPK30.26759348
127MAPKAPK20.26160053
128TAOK20.25306061
129PIK3CG0.25020930
130MAPK40.24376490
131DDR20.24176145
132PDGFRA0.23515249
133PDK10.23403735
134BCR0.22485387
135LYN0.21443409
136MAPKAPK30.21069840
137SRC0.20171670
138CDK90.19979136
139ILK0.19252110
140STK110.18680515
141TRPM70.17874551
142CDK40.17617987

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051508.10597435
2Other glycan degradation_Homo sapiens_hsa005115.51430350
3Complement and coagulation cascades_Homo sapiens_hsa046104.86802556
4Autoimmune thyroid disease_Homo sapiens_hsa053204.33898952
5Asthma_Homo sapiens_hsa053104.32950801
6Allograft rejection_Homo sapiens_hsa053304.22489180
7Graft-versus-host disease_Homo sapiens_hsa053323.76661799
8Glycosaminoglycan degradation_Homo sapiens_hsa005313.54758294
9Primary immunodeficiency_Homo sapiens_hsa053403.37281788
10Type I diabetes mellitus_Homo sapiens_hsa049403.24580537
11Pertussis_Homo sapiens_hsa051333.07932019
12Caffeine metabolism_Homo sapiens_hsa002322.84522161
13Arachidonic acid metabolism_Homo sapiens_hsa005902.15060773
14Prion diseases_Homo sapiens_hsa050202.04951131
15Leishmaniasis_Homo sapiens_hsa051402.00893227
16Linoleic acid metabolism_Homo sapiens_hsa005911.97049500
17Malaria_Homo sapiens_hsa051441.95128719
18Lysosome_Homo sapiens_hsa041421.86684291
19Nitrogen metabolism_Homo sapiens_hsa009101.82673776
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.79381277
21T cell receptor signaling pathway_Homo sapiens_hsa046601.70905721
22Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.63182266
23Fat digestion and absorption_Homo sapiens_hsa049751.56744856
24Herpes simplex infection_Homo sapiens_hsa051681.52099590
25Arginine biosynthesis_Homo sapiens_hsa002201.30499525
26Amoebiasis_Homo sapiens_hsa051461.28220594
27alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.21963566
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.21505114
29Histidine metabolism_Homo sapiens_hsa003401.21259499
30Osteoclast differentiation_Homo sapiens_hsa043801.07122656
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.05760470
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.05562824
33RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.03706235
34Pentose and glucuronate interconversions_Homo sapiens_hsa000400.98955935
35Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.98503751
36Renin-angiotensin system_Homo sapiens_hsa046140.96074288
37Phagosome_Homo sapiens_hsa041450.93302056
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.92912595
39Legionellosis_Homo sapiens_hsa051340.91890470
40Hematopoietic cell lineage_Homo sapiens_hsa046400.90900594
41Tuberculosis_Homo sapiens_hsa051520.89624093
42Leukocyte transendothelial migration_Homo sapiens_hsa046700.88269298
43ABC transporters_Homo sapiens_hsa020100.87915444
44Epstein-Barr virus infection_Homo sapiens_hsa051690.81988559
45Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81789264
46Toxoplasmosis_Homo sapiens_hsa051450.77474540
47PPAR signaling pathway_Homo sapiens_hsa033200.76993137
48* Chemokine signaling pathway_Homo sapiens_hsa040620.70702925
49Platelet activation_Homo sapiens_hsa046110.70373212
50African trypanosomiasis_Homo sapiens_hsa051430.67871949
51HTLV-I infection_Homo sapiens_hsa051660.66882304
52Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.66193657
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65674279
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.64693340
55Fatty acid degradation_Homo sapiens_hsa000710.62314682
56Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59768592
57Proteoglycans in cancer_Homo sapiens_hsa052050.57670200
58Ether lipid metabolism_Homo sapiens_hsa005650.56202554
59Vitamin digestion and absorption_Homo sapiens_hsa049770.56187185
60Pancreatic cancer_Homo sapiens_hsa052120.56143510
61Apoptosis_Homo sapiens_hsa042100.55429102
62B cell receptor signaling pathway_Homo sapiens_hsa046620.54489018
63Intestinal immune network for IgA production_Homo sapiens_hsa046720.53770612
64Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52331724
65Sulfur metabolism_Homo sapiens_hsa009200.50788222
66Chronic myeloid leukemia_Homo sapiens_hsa052200.50096614
67Starch and sucrose metabolism_Homo sapiens_hsa005000.49330909
68NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48508551
69Mineral absorption_Homo sapiens_hsa049780.48360717
70Adipocytokine signaling pathway_Homo sapiens_hsa049200.47390570
71Tryptophan metabolism_Homo sapiens_hsa003800.46937618
72Lysine degradation_Homo sapiens_hsa003100.46735129
73Prolactin signaling pathway_Homo sapiens_hsa049170.45295559
74Salmonella infection_Homo sapiens_hsa051320.45098115
75Dorso-ventral axis formation_Homo sapiens_hsa043200.44278708
76Carbohydrate digestion and absorption_Homo sapiens_hsa049730.43638583
77Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.43025890
78Toll-like receptor signaling pathway_Homo sapiens_hsa046200.42618451
79beta-Alanine metabolism_Homo sapiens_hsa004100.42459963
80Protein digestion and absorption_Homo sapiens_hsa049740.42316649
81Jak-STAT signaling pathway_Homo sapiens_hsa046300.41960617
82Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41586941
83Acute myeloid leukemia_Homo sapiens_hsa052210.40962980
84Insulin resistance_Homo sapiens_hsa049310.38785671
85Retinol metabolism_Homo sapiens_hsa008300.38607492
86Small cell lung cancer_Homo sapiens_hsa052220.38461426
87Fructose and mannose metabolism_Homo sapiens_hsa000510.38045445
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.37977135
89ECM-receptor interaction_Homo sapiens_hsa045120.37750024
90Antigen processing and presentation_Homo sapiens_hsa046120.37585015
91Focal adhesion_Homo sapiens_hsa045100.37484509
92Systemic lupus erythematosus_Homo sapiens_hsa053220.37397616
93Rheumatoid arthritis_Homo sapiens_hsa053230.35661056
94NF-kappa B signaling pathway_Homo sapiens_hsa040640.35374300
95Phenylalanine metabolism_Homo sapiens_hsa003600.34887019
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33727613
97Bile secretion_Homo sapiens_hsa049760.33587994
98Rap1 signaling pathway_Homo sapiens_hsa040150.33580710
99Fatty acid metabolism_Homo sapiens_hsa012120.32980063
100Adherens junction_Homo sapiens_hsa045200.32886452
101Peroxisome_Homo sapiens_hsa041460.32676288
102Pancreatic secretion_Homo sapiens_hsa049720.31827546
103Shigellosis_Homo sapiens_hsa051310.30001780
104Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.29728088
105Viral carcinogenesis_Homo sapiens_hsa052030.29518996
106Hepatitis C_Homo sapiens_hsa051600.29160895
107Glycerolipid metabolism_Homo sapiens_hsa005610.27691476
108Endocytosis_Homo sapiens_hsa041440.26806973
109* Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26290638
110Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.24412155
111Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.24346840
112Viral myocarditis_Homo sapiens_hsa054160.23942436
113Steroid hormone biosynthesis_Homo sapiens_hsa001400.22863449
114Drug metabolism - other enzymes_Homo sapiens_hsa009830.22770216
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.22333624
116N-Glycan biosynthesis_Homo sapiens_hsa005100.22320186
117Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.22019377
118Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.21104026
119Chemical carcinogenesis_Homo sapiens_hsa052040.21043089
120Serotonergic synapse_Homo sapiens_hsa047260.20653151
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.19863093
122Pathways in cancer_Homo sapiens_hsa052000.19772319
123MAPK signaling pathway_Homo sapiens_hsa040100.19091577
124VEGF signaling pathway_Homo sapiens_hsa043700.18478202
125Propanoate metabolism_Homo sapiens_hsa006400.17929275
126Vascular smooth muscle contraction_Homo sapiens_hsa042700.15097977
127Sulfur relay system_Homo sapiens_hsa041220.14632886
128TNF signaling pathway_Homo sapiens_hsa046680.14316401
129Measles_Homo sapiens_hsa051620.13861401
130Influenza A_Homo sapiens_hsa051640.13479441
131TGF-beta signaling pathway_Homo sapiens_hsa043500.12736717
132Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.12582671
133Fatty acid biosynthesis_Homo sapiens_hsa000610.12456525
134Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.11921460
135Dilated cardiomyopathy_Homo sapiens_hsa054140.11750179
136Hepatitis B_Homo sapiens_hsa051610.10933929

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »