CXCL16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.58203765
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.23139841
3negative regulation of interleukin-12 production (GO:0032695)4.82523014
4response to peptidoglycan (GO:0032494)4.67735984
5regulation of dendritic cell antigen processing and presentation (GO:0002604)4.61024259
6NIK/NF-kappaB signaling (GO:0038061)4.59044027
7positive regulation by symbiont of host defense response (GO:0052509)4.52234899
8modulation by symbiont of host defense response (GO:0052031)4.52234899
9modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.52234899
10modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.52234899
11positive regulation by organism of defense response of other organism involved in symbiotic interact4.52234899
12modulation by symbiont of host immune response (GO:0052553)4.52234899
13granulocyte activation (GO:0036230)4.37286487
14neutrophil activation (GO:0042119)4.35731107
15positive regulation of interferon-alpha production (GO:0032727)4.33779131
16positive regulation of antigen processing and presentation (GO:0002579)4.28813843
17response to muramyl dipeptide (GO:0032495)4.09535923
18regulation of interferon-alpha production (GO:0032647)4.08784493
19immunoglobulin mediated immune response (GO:0016064)4.04240230
20natural killer cell mediated immunity (GO:0002228)4.01868751
21natural killer cell mediated cytotoxicity (GO:0042267)4.01868751
22positive regulation of cellular amide metabolic process (GO:0034250)4.01844416
23antigen processing and presentation of endogenous antigen (GO:0019883)4.00006677
24positive regulation of interleukin-12 production (GO:0032735)3.91013205
25myeloid dendritic cell differentiation (GO:0043011)3.86561885
26regulation of T-helper 1 cell differentiation (GO:0045625)3.83984282
27regulation of activation of Janus kinase activity (GO:0010533)3.82790970
28T-helper 1 type immune response (GO:0042088)3.82677073
29cellular response to type I interferon (GO:0071357)3.81108580
30type I interferon signaling pathway (GO:0060337)3.81108580
31positive regulation of type 2 immune response (GO:0002830)3.77769010
32lipopolysaccharide-mediated signaling pathway (GO:0031663)3.77487115
33response to type I interferon (GO:0034340)3.76933645
34regulation of antigen processing and presentation (GO:0002577)3.74224526
35macrophage activation involved in immune response (GO:0002281)3.73889273
36interferon-gamma-mediated signaling pathway (GO:0060333)3.73668547
37positive regulation of gamma-delta T cell activation (GO:0046645)3.68989514
38hydrogen peroxide biosynthetic process (GO:0050665)3.64791536
39positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.62814771
40detection of molecule of bacterial origin (GO:0032490)3.61352956
41negative regulation of cell killing (GO:0031342)3.61161188
42negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.61161188
43respiratory burst (GO:0045730)3.55402808
44positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.54209906
45regulation of interleukin-12 biosynthetic process (GO:0045075)3.52117040
46antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.50293173
47antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.50293173
48positive regulation of natural killer cell differentiation (GO:0032825)3.48192027
49myeloid dendritic cell activation (GO:0001773)3.45952819
50regulation of mast cell degranulation (GO:0043304)3.44010906
51regulation of interferon-beta biosynthetic process (GO:0045357)3.43758089
52regulation of RIG-I signaling pathway (GO:0039535)3.43741536
53detection of other organism (GO:0098543)3.42146457
54cellular extravasation (GO:0045123)3.41506772
55glycosphingolipid catabolic process (GO:0046479)3.41336654
56positive regulation of monocyte chemotaxis (GO:0090026)3.38845605
57oligosaccharide catabolic process (GO:0009313)3.36501536
58regulation of hypersensitivity (GO:0002883)3.34674220
59microglial cell activation (GO:0001774)3.32645775
60positive regulation of mast cell activation (GO:0033005)3.31147364
61dendritic cell differentiation (GO:0097028)3.28229476
62positive regulation of chemokine biosynthetic process (GO:0045080)3.28070193
63monocyte chemotaxis (GO:0002548)3.27756071
64superoxide anion generation (GO:0042554)3.27569174
65negative regulation of interleukin-17 production (GO:0032700)3.22892529
66regulation of mononuclear cell migration (GO:0071675)3.21594775
67response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.21268332
68response to host immune response (GO:0052572)3.21268332
69cellular response to thyroid hormone stimulus (GO:0097067)3.21190762
70leukocyte mediated cytotoxicity (GO:0001909)3.20667481
71positive regulation of heat generation (GO:0031652)3.19798244
72positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.19472704
73regulation of T-helper 2 cell differentiation (GO:0045628)3.18471034
74reactive oxygen species biosynthetic process (GO:1903409)3.16432469
75cytokine secretion (GO:0050663)3.16106910
76detection of external biotic stimulus (GO:0098581)3.15973234
77regulation of mast cell activation involved in immune response (GO:0033006)3.15750408
78regulation of interleukin-12 production (GO:0032655)3.15572349
79positive regulation of interferon-beta production (GO:0032728)3.15483533
80regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.14194817
81regulation of vitamin D biosynthetic process (GO:0060556)3.14176927
82positive regulation of T-helper cell differentiation (GO:0045624)3.13175246
83detection of bacterium (GO:0016045)3.12639048
84response to interferon-alpha (GO:0035455)3.11265873
85growth hormone receptor signaling pathway (GO:0060396)3.10901187
86glycolipid catabolic process (GO:0019377)3.08323230
87positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.07740765
88B cell mediated immunity (GO:0019724)3.06194192
89regulation of myeloid leukocyte mediated immunity (GO:0002886)3.05681726
90regulation of fever generation (GO:0031620)3.03710721
91positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.03319387
92defense response to protozoan (GO:0042832)3.02326140
93germinal center formation (GO:0002467)3.00584996
94myeloid cell activation involved in immune response (GO:0002275)3.00009534
95cellular response to interferon-gamma (GO:0071346)2.99634233
96positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.99000440
97production of molecular mediator involved in inflammatory response (GO:0002532)2.98954573
98regulation of leukocyte degranulation (GO:0043300)2.98659514
99positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.98236028
100negative regulation of viral genome replication (GO:0045071)2.98078780
101regulation of mast cell activation (GO:0033003)2.97256856
102amino sugar catabolic process (GO:0046348)2.96446449
103regulation of gamma-delta T cell activation (GO:0046643)2.96367426
104cellular response to interferon-beta (GO:0035458)2.95951660
105regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.94371734
106positive regulation of leukocyte degranulation (GO:0043302)2.93111156
107JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.93082171
108regulation of T cell tolerance induction (GO:0002664)2.92756004
109regulation of macrophage chemotaxis (GO:0010758)2.91445200
110macrophage activation (GO:0042116)2.91342915
111lymphocyte mediated immunity (GO:0002449)2.90793374
112detection of biotic stimulus (GO:0009595)2.90674659
113cellular response to interferon-alpha (GO:0035457)2.89767359
114regulation of podosome assembly (GO:0071801)2.89228143
115regulation of chemokine biosynthetic process (GO:0045073)2.89192609
116positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.89017693
117cellular response to zinc ion (GO:0071294)2.88268372
118positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.87191894
119eosinophil chemotaxis (GO:0048245)2.85323112
120regulation of monocyte chemotaxis (GO:0090025)2.84308051
121negative regulation of cytokine production involved in immune response (GO:0002719)2.84255365
122response to host (GO:0075136)2.83738106
123response to host defenses (GO:0052200)2.83738106
124response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.83738106
125regulation of immunoglobulin secretion (GO:0051023)2.83625726
126regulation of tolerance induction (GO:0002643)2.82892576
127positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.82652124
128myeloid leukocyte activation (GO:0002274)2.81148322
129positive regulation of mast cell activation involved in immune response (GO:0033008)2.80797128
130positive regulation of mast cell degranulation (GO:0043306)2.80797128
131regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.80592281
132positive regulation of humoral immune response (GO:0002922)2.80254899
133response to protozoan (GO:0001562)2.79566081
134peptide catabolic process (GO:0043171)2.79351343
135negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.75641912
136positive regulation of toll-like receptor signaling pathway (GO:0034123)2.75378633
137positive regulation of NF-kappaB import into nucleus (GO:0042346)2.73317168
138ceramide catabolic process (GO:0046514)2.72949734
139regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.70032197
140positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.69891121
141regulation of vitamin metabolic process (GO:0030656)2.64687359
142negative regulation of myeloid cell apoptotic process (GO:0033033)2.59401452
143regulation of type 2 immune response (GO:0002828)2.57635546
144response to thyroid hormone (GO:0097066)2.57135537
145neutrophil chemotaxis (GO:0030593)2.50818618
146negative regulation of interleukin-1 beta production (GO:0032691)2.50795120
147negative regulation of erythrocyte differentiation (GO:0045647)2.50412067

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.92168650
2IRF8_21731497_ChIP-ChIP_J774_Mouse6.60555832
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.76648990
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.69313492
5* IRF8_27001747_Chip-Seq_BMDM_Mouse4.19876696
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.18297065
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.08814203
8TP63_17297297_ChIP-ChIP_HaCaT_Human3.75920038
9* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.67657442
10RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.65232215
11Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.49042742
12NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.31110711
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.89902929
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.72584105
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.51756639
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.42953740
17STAT4_19710469_ChIP-ChIP_TH1__Mouse2.42293509
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.42106417
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.38853973
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.31426671
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.26682484
22STAT6_21828071_ChIP-Seq_BEAS2B_Human2.14051029
23STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.10720912
24NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.99907131
25VDR_24787735_ChIP-Seq_THP-1_Human1.94107424
26LXR_22292898_ChIP-Seq_THP-1_Human1.84435484
27GATA1_22025678_ChIP-Seq_K562_Human1.72536932
28SMAD_19615063_ChIP-ChIP_OVARY_Human1.71798595
29PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.70536314
30BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69055572
31KDM2B_26808549_Chip-Seq_SUP-B15_Human1.66130441
32SPI1_23547873_ChIP-Seq_NB4_Human1.63637417
33PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.63042766
34RUNX_20019798_ChIP-Seq_JUKART_Human1.56332192
35PU_27001747_Chip-Seq_BMDM_Mouse1.54893655
36ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.51186161
37GATA2_21666600_ChIP-Seq_HMVEC_Human1.49186073
38THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.48681153
39RXR_22158963_ChIP-Seq_LIVER_Mouse1.47810451
40MYB_26560356_Chip-Seq_TH2_Human1.46803384
41TRIM28_21343339_ChIP-Seq_HEK293_Human1.45261026
42CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.43505359
43FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.40367687
44TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.40006328
45PPARA_22158963_ChIP-Seq_LIVER_Mouse1.39561613
46* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.38656731
47VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.38195997
48VDR_24763502_ChIP-Seq_THP-1_Human1.37212240
49GATA1_19941827_ChIP-Seq_MEL_Mouse1.36281359
50TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.34387566
51MAF_26560356_Chip-Seq_TH1_Human1.31219767
52SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30785481
53SPI1_23127762_ChIP-Seq_K562_Human1.27739550
54FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.27110631
55GATA1_19941826_ChIP-Seq_K562_Human1.25506613
56* BCL6_27268052_Chip-Seq_Bcells_Human1.20677614
57SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.19067710
58* BCOR_27268052_Chip-Seq_Bcells_Human1.18717441
59CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.18435678
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18338683
61EGR1_19032775_ChIP-ChIP_M12_Human1.18108475
62CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15913196
63RUNX1_22412390_ChIP-Seq_EML_Mouse1.13817010
64KDM2B_26808549_Chip-Seq_DND41_Human1.13059059
65TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.12930194
66STAT1_20625510_ChIP-Seq_HELA_Human1.12012735
67* SOX2_20726797_ChIP-Seq_SW620_Human1.11882257
68SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.11176702
69SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.11176702
70NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10931760
71GATA3_26560356_Chip-Seq_TH2_Human1.10491238
72CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09259420
73TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09068386
74NRF2_20460467_ChIP-Seq_MEFs_Mouse1.08413280
75NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.08413280
76MYB_26560356_Chip-Seq_TH1_Human1.07575002
77RACK7_27058665_Chip-Seq_MCF-7_Human1.07330774
78* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07020462
79GATA3_27048872_Chip-Seq_THYMUS_Human1.06874318
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06744113
81KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.06041413
82VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.05205352
83CJUN_26792858_Chip-Seq_BT549_Human1.04100119
84CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.04045363
85UTX_26944678_Chip-Seq_JUKART_Human1.02374026
86RARG_19884340_ChIP-ChIP_MEFs_Mouse1.01465826
87SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98925060
88MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.98224931
89ELF1_20517297_ChIP-Seq_JURKAT_Human0.96713367
90ESR1_21235772_ChIP-Seq_MCF-7_Human0.96491973
91SCL_19346495_ChIP-Seq_HPC-7_Human0.96402687
92GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95861923
93CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.95231314
94GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95112260
95JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93929115
96RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.93812675
97TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.92651655
98GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91645426
99IKZF1_21737484_ChIP-ChIP_HCT116_Human0.91528725
100GATA2_19941826_ChIP-Seq_K562_Human0.89571549
101JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89385107
102* KDM2B_26808549_Chip-Seq_K562_Human0.87648747
103LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.87357109
104P63_26484246_Chip-Seq_KERATINOCYTES_Human0.86501153
105MAF_26560356_Chip-Seq_TH2_Human0.85710372
106FOXO3_23340844_ChIP-Seq_DLD1_Human0.83845180
107SMC4_20622854_ChIP-Seq_HELA_Human0.82427620
108FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.82000118
109ELK3_25401928_ChIP-Seq_HUVEC_Human0.81852772
110GATA2_22383799_ChIP-Seq_G1ME_Mouse0.80905216
111SA1_27219007_Chip-Seq_Bcells_Human0.80756013
112P68_20966046_ChIP-Seq_HELA_Human0.80022422
113PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79522764
114GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.79272570
115E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.79237992
116MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.79141889
117CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.78758307
118EGR1_23403033_ChIP-Seq_LIVER_Mouse0.78514020
119ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.77749189
120VDR_21846776_ChIP-Seq_THP-1_Human0.76599839
121LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.75702635
122PPAR_26484153_Chip-Seq_NCI-H1993_Human0.73910428
123SMRT_27268052_Chip-Seq_Bcells_Human0.71803207
124ESR2_21235772_ChIP-Seq_MCF-7_Human0.71618992
125RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.65650760
126BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.65635570
127ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.64309777
128LXR_22158963_ChIP-Seq_LIVER_Mouse0.63705340
129TCF7_22412390_ChIP-Seq_EML_Mouse0.63619344
130GATA4_25053715_ChIP-Seq_YYC3_Human0.63051159
131TP53_18474530_ChIP-ChIP_U2OS_Human0.62815399

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.83107187
2MP0002148_abnormal_hypersensitivity_rea3.85866310
3MP0009785_altered_susceptibility_to3.80784003
4MP0003436_decreased_susceptibility_to3.65677382
5MP0004510_myositis3.23352464
6MP0000685_abnormal_immune_system3.19193841
7MP0002138_abnormal_hepatobiliary_system3.19094043
8MP0005000_abnormal_immune_tolerance3.04664915
9MP0001790_abnormal_immune_system2.92768261
10MP0005387_immune_system_phenotype2.92768261
11* MP0002419_abnormal_innate_immunity2.85944975
12* MP0005025_abnormal_response_to2.77591054
13MP0003303_peritoneal_inflammation2.76380296
14MP0005671_abnormal_response_to2.63208856
15MP0006082_CNS_inflammation2.62979444
16MP0002254_reproductive_system_inflammat2.61056365
17MP0003724_increased_susceptibility_to2.47828915
18* MP0002452_abnormal_antigen_presenting2.46716695
19MP0001800_abnormal_humoral_immune2.38812741
20* MP0002723_abnormal_immune_serum2.32827567
21MP0002139_abnormal_hepatobiliary_system2.29954906
22MP0002006_tumorigenesis2.21615260
23MP0005058_abnormal_lysosome_morphology2.08928281
24* MP0001819_abnormal_immune_cell2.05893191
25MP0005310_abnormal_salivary_gland2.04926795
26MP0009764_decreased_sensitivity_to2.02720570
27MP0002166_altered_tumor_susceptibility2.01204810
28* MP0002420_abnormal_adaptive_immunity2.00690167
29MP0001853_heart_inflammation1.98613985
30MP0001533_abnormal_skeleton_physiology1.95819835
31MP0004947_skin_inflammation1.94517268
32MP0005451_abnormal_body_composition1.88979650
33MP0008004_abnormal_stomach_pH1.86205924
34MP0001845_abnormal_inflammatory_respons1.77917562
35MP0002277_abnormal_respiratory_mucosa1.71081254
36MP0002405_respiratory_system_inflammati1.70921097
37MP0010155_abnormal_intestine_physiology1.68039172
38MP0005464_abnormal_platelet_physiology1.66831419
39* MP0003448_altered_tumor_morphology1.64562748
40MP0001348_abnormal_lacrimal_gland1.56350341
41* MP0008469_abnormal_protein_level1.54897522
42MP0003075_altered_response_to1.52085515
43MP0002998_abnormal_bone_remodeling1.51169932
44MP0005167_abnormal_blood-brain_barrier1.44194223
45MP0003191_abnormal_cellular_cholesterol1.43692682
46* MP0000716_abnormal_immune_system1.41873850
47MP0005365_abnormal_bile_salt1.40315769
48MP0000858_altered_metastatic_potential1.37110485
49MP0000569_abnormal_digit_pigmentation1.35457388
50MP0003806_abnormal_nucleotide_metabolis1.33586896
51MP0000343_altered_response_to1.31664376
52MP0009333_abnormal_splenocyte_physiolog1.30481602
53MP0005410_abnormal_fertilization1.29783373
54MP0009278_abnormal_bone_marrow1.28826375
55MP0002163_abnormal_gland_morphology1.28418587
56MP0000604_amyloidosis1.27948918
57MP0009840_abnormal_foam_cell1.27456736
58MP0002398_abnormal_bone_marrow1.24243512
59MP0001545_abnormal_hematopoietic_system1.24196254
60MP0005397_hematopoietic_system_phenotyp1.24196254
61MP0008260_abnormal_autophagy1.23425813
62MP0004782_abnormal_surfactant_physiolog1.21985767
63MP0005076_abnormal_cell_differentiation1.18250506
64MP0003453_abnormal_keratinocyte_physiol1.17531611
65MP0003195_calcinosis1.17505198
66MP0003300_gastrointestinal_ulcer1.16696342
67MP0005166_decreased_susceptibility_to1.14800756
68MP0001346_abnormal_lacrimal_gland1.11237690
69MP0003172_abnormal_lysosome_physiology1.11019255
70MP0003091_abnormal_cell_migration1.10218396
71MP0003656_abnormal_erythrocyte_physiolo1.09488814
72MP0003566_abnormal_cell_adhesion1.09299586
73* MP0002429_abnormal_blood_cell1.06364811
74MP0003329_amyloid_beta_deposits1.03503482
75MP0005164_abnormal_response_to1.02902830
76MP0002132_abnormal_respiratory_system1.00731816
77MP0005390_skeleton_phenotype0.99051866
78MP0003186_abnormal_redox_activity0.98208242
79MP0000689_abnormal_spleen_morphology0.96933752
80MP0009763_increased_sensitivity_to0.95365790
81MP0002009_preneoplasia0.93707436
82MP0000920_abnormal_myelination0.93274348
83MP0000465_gastrointestinal_hemorrhage0.91739865
84MP0002722_abnormal_immune_system0.89474570
85MP0003828_pulmonary_edema0.89295573
86MP0001958_emphysema0.87692399
87MP0002877_abnormal_melanocyte_morpholog0.87240110
88MP0008438_abnormal_cutaneous_collagen0.85057523
89MP0002933_joint_inflammation0.85005652
90MP0006054_spinal_hemorrhage0.84238252
91MP0002136_abnormal_kidney_physiology0.83213665
92MP0004019_abnormal_vitamin_homeostasis0.83181836
93MP0009765_abnormal_xenobiotic_induced0.82441062
94MP0010307_abnormal_tumor_latency0.80958433
95MP0001663_abnormal_digestive_system0.79385869
96MP0000678_abnormal_parathyroid_gland0.79036672
97MP0005275_abnormal_skin_tensile0.76702695
98MP0000767_abnormal_smooth_muscle0.76117572
99MP0000627_abnormal_mammary_gland0.75738601
100MP0001881_abnormal_mammary_gland0.74558989
101MP0003690_abnormal_glial_cell0.74325133
102MP0005023_abnormal_wound_healing0.74306192
103MP0010352_gastrointestinal_tract_polyps0.74166344
104MP0003866_abnormal_defecation0.71903746
105* MP0000249_abnormal_blood_vessel0.71467422
106MP0001873_stomach_inflammation0.70488636
107MP0005083_abnormal_biliary_tract0.70466319
108MP0000609_abnormal_liver_physiology0.70040590
109MP0005319_abnormal_enzyme/_coenzyme0.69745461
110MP0000371_diluted_coat_color0.68093016
111MP0005257_abnormal_intraocular_pressure0.65961237
112MP0005647_abnormal_sex_gland0.65847651
113MP0008875_abnormal_xenobiotic_pharmacok0.65363161
114MP0005165_increased_susceptibility_to0.65000581
115MP0001879_abnormal_lymphatic_vessel0.64826609
116MP0005085_abnormal_gallbladder_physiolo0.64343943
117MP0002295_abnormal_pulmonary_circulatio0.64240648
118MP0001851_eye_inflammation0.61890143
119MP0003879_abnormal_hair_cell0.61633956
120MP0003795_abnormal_bone_structure0.60587225
121MP0002118_abnormal_lipid_homeostasis0.59152555
122MP0002332_abnormal_exercise_endurance0.58865303
123MP0003183_abnormal_peptide_metabolism0.58180838
124MP0004883_abnormal_blood_vessel0.57766982
125MP0005584_abnormal_enzyme/coenzyme_acti0.57589914
126MP0004858_abnormal_nervous_system0.57327900
127MP0003763_abnormal_thymus_physiology0.56393319
128MP0005379_endocrine/exocrine_gland_phen0.56245438
129MP0003045_fibrosis0.55981050
130MP0001216_abnormal_epidermal_layer0.54957145

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.60537616
2Recurrent abscess formation (HP:0002722)6.58556558
3Recurrent bacterial skin infections (HP:0005406)6.29810295
4Recurrent gram-negative bacterial infections (HP:0005420)5.38083113
5Mediastinal lymphadenopathy (HP:0100721)4.99725629
6Abnormality of macrophages (HP:0004311)4.96326411
7Systemic lupus erythematosus (HP:0002725)4.59672036
8Autoimmune thrombocytopenia (HP:0001973)4.56351791
9Elevated erythrocyte sedimentation rate (HP:0003565)4.32599306
10Increased IgM level (HP:0003496)4.28881457
11Orchitis (HP:0100796)4.22700251
12Optic neuritis (HP:0100653)4.15227289
13Retrobulbar optic neuritis (HP:0100654)4.15227289
14Myositis (HP:0100614)4.01588542
15Gingivitis (HP:0000230)3.96675215
16Gastrointestinal infarctions (HP:0005244)3.89549386
17Recurrent skin infections (HP:0001581)3.81026611
18Thick nail (HP:0001805)3.80401725
19Recurrent fungal infections (HP:0002841)3.70820139
20Glomerulonephritis (HP:0000099)3.61581673
21Vasculitis (HP:0002633)3.60811802
22Myocardial infarction (HP:0001658)3.59138680
23Vacuolated lymphocytes (HP:0001922)3.55197248
24Purpura (HP:0000979)3.43715424
25Recurrent viral infections (HP:0004429)3.35623671
26Prostate neoplasm (HP:0100787)3.35498048
27Stomatitis (HP:0010280)3.32275661
28Abnormality of mucopolysaccharide metabolism (HP:0011020)3.30475088
29Abnormality of polysaccharide metabolism (HP:0011012)3.30475088
30Abnormality of glycosaminoglycan metabolism (HP:0004371)3.30475088
31Interstitial pulmonary disease (HP:0006530)3.27851763
32Obstructive lung disease (HP:0006536)3.27051780
33Chronic obstructive pulmonary disease (HP:0006510)3.27051780
34Basal ganglia calcification (HP:0002135)3.25872344
35Tetraparesis (HP:0002273)3.24459011
36Urinary glycosaminoglycan excretion (HP:0003541)3.13292996
37Pustule (HP:0200039)3.11908682
38Periodontitis (HP:0000704)3.11425089
39Increased cerebral lipofuscin (HP:0011813)3.10803447
40Chronic otitis media (HP:0000389)3.10424461
41Pulmonary infiltrates (HP:0002113)3.10122047
42Axonal loss (HP:0003447)3.03927221
43Increased neuronal autofluorescent lipopigment (HP:0002074)2.92588739
44Hypergammaglobulinemia (HP:0010702)2.90570774
45Increased serum ferritin (HP:0003281)2.90407515
46Arterial thrombosis (HP:0004420)2.84345408
47Hematochezia (HP:0002573)2.82959879
48Mutism (HP:0002300)2.80256215
49Nephritis (HP:0000123)2.78424528
50Urticaria (HP:0001025)2.73020072
51Cellulitis (HP:0100658)2.72011166
52Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.70241645
53Osteolytic defects of the hand bones (HP:0009699)2.69933218
54Osteolytic defects of the phalanges of the hand (HP:0009771)2.69933218
55Neurofibrillary tangles (HP:0002185)2.69531715
56Leukocytosis (HP:0001974)2.68815070
57Petechiae (HP:0000967)2.67576606
58Peritonitis (HP:0002586)2.63300290
59Premature loss of primary teeth (HP:0006323)2.55695949
60Malnutrition (HP:0004395)2.53201349
61Esophageal varix (HP:0002040)2.48929044
62Recurrent cutaneous fungal infections (HP:0011370)2.47659320
63Chronic mucocutaneous candidiasis (HP:0002728)2.47659320
64Gingival bleeding (HP:0000225)2.47272294
65Eosinophilia (HP:0001880)2.43983517
66Metaphyseal irregularity (HP:0003025)2.43647895
67Abnormality of glycolipid metabolism (HP:0010969)2.43502259
68Abnormality of liposaccharide metabolism (HP:0010968)2.43502259
69Abnormality of glycosphingolipid metabolism (HP:0004343)2.43502259
70Nasal polyposis (HP:0100582)2.39688130
71Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.38055220
72Hemoptysis (HP:0002105)2.38032043
73Abnormality of iron homeostasis (HP:0011031)2.37484306
74Keratoconjunctivitis sicca (HP:0001097)2.35690918
75Hydroxyprolinuria (HP:0003080)2.35500933
76Abnormality of proline metabolism (HP:0010907)2.35500933
77Asymmetric septal hypertrophy (HP:0001670)2.34592042
78Meningitis (HP:0001287)2.34305988
79Osteomyelitis (HP:0002754)2.31575151
80Recurrent pneumonia (HP:0006532)2.30720802
81Progressive visual loss (HP:0000529)2.29720825
82Vertebral compression fractures (HP:0002953)2.28965985
83Disinhibition (HP:0000734)2.27945069
84Increased IgE level (HP:0003212)2.25486596
85Progressive neurologic deterioration (HP:0002344)2.25218761
86Bone pain (HP:0002653)2.25115764
87Porencephaly (HP:0002132)2.24208050
88Episodic fever (HP:0001954)2.23745227
89Abnormality of the nasal mucosa (HP:0000433)2.23196596
90Keratoconjunctivitis (HP:0001096)2.20495819
91Abnormality of complement system (HP:0005339)2.20063144
92Autoimmune hemolytic anemia (HP:0001890)2.18312323
93Epistaxis (HP:0000421)2.15645883
94Prolonged bleeding time (HP:0003010)2.14046840
95Retinal atrophy (HP:0001105)2.12371433
96Amyloidosis (HP:0011034)2.10932553
97Recurrent lower respiratory tract infections (HP:0002783)2.09866846
98Abnormality of the pericardium (HP:0001697)2.09617840
99Dysostosis multiplex (HP:0000943)2.09184537
100Emphysema (HP:0002097)2.06894141
101Pulmonary embolism (HP:0002204)2.06233299
102Abnormality of transition element cation homeostasis (HP:0011030)2.06141734
103Neuronal loss in central nervous system (HP:0002529)2.05921487
104Granulocytopenia (HP:0001913)2.05466310
105Pulmonary artery stenosis (HP:0004415)2.04063603
106Anorexia (HP:0002039)2.03392949
107Abnormality of the vasculature of the conjunctiva (HP:0008054)2.02939689
108Cerebral inclusion bodies (HP:0100314)2.02280653
109Loss of speech (HP:0002371)2.01254735
110Arthralgia (HP:0002829)2.00066534
111Fatigue (HP:0012378)1.99827493
112Spontaneous hematomas (HP:0007420)1.99232459
113Complement deficiency (HP:0004431)1.98624700
114Joint swelling (HP:0001386)1.98460841
115Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.98273060
116Hepatosplenomegaly (HP:0001433)1.97962137
117Diminished motivation (HP:0000745)1.97783217
118Polyneuropathy (HP:0001271)1.97704982
119Chest pain (HP:0100749)1.97499696
120Segmental peripheral demyelination/remyelination (HP:0003481)1.97174105
121Apathy (HP:0000741)1.96725808
122Gangrene (HP:0100758)1.96301818
123Encephalitis (HP:0002383)1.96135373
124Nuclear cataract (HP:0100018)1.95837298
125Skin ulcer (HP:0200042)1.94530724
126Abnormality of T cell number (HP:0011839)1.94114048
127Thrombocytosis (HP:0001894)1.93290610
128Anhidrosis (HP:0000970)1.93157662
129Abnormality of eosinophils (HP:0001879)1.92342932
130Acne (HP:0001061)1.91056539
131Xanthomatosis (HP:0000991)1.89822940
132Pathologic fracture (HP:0002756)1.88868466
133Thin bony cortex (HP:0002753)1.88509285
134Polycythemia (HP:0001901)1.86834425
135Colitis (HP:0002583)1.85454083
136Mucopolysacchariduria (HP:0008155)1.85304918
137Vertigo (HP:0002321)1.83858198
138Increased CSF protein (HP:0002922)1.82452292
139Peripheral demyelination (HP:0011096)1.81985768
140Restrictive lung disease (HP:0002091)1.79482473
141Dementia (HP:0000726)1.79285493

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K145.67755483
2RIPK44.05785655
3TBK13.87414488
4TYK23.53035336
5IKBKB3.35911585
6IKBKE3.04784172
7PBK3.00403407
8BLK2.90443721
9JAK32.88404470
10MAP3K132.82408272
11IRAK42.77865610
12IRAK32.53386210
13CHUK2.44445594
14JAK12.29917702
15DDR22.28019835
16PIM22.09873053
17TAOK11.92275714
18KIT1.70683507
19NEK91.67942139
20MST41.64026377
21EPHB11.59307953
22TAOK21.52801549
23BMPR21.50659050
24PRPF4B1.49516319
25CDC42BPA1.45290464
26CSK1.35812005
27BMX1.30917407
28FGFR41.27408195
29EPHA31.22005274
30ACVR1B1.21889658
31TXK1.19837094
32JAK21.17772073
33PDPK11.16117572
34ERN11.14738073
35TGFBR21.14486618
36ZAP701.14075503
37PIM11.12956417
38MST1R1.12077172
39MAP4K11.10816483
40FES1.05046697
41RPS6KA41.04210771
42ABL21.01738498
43SYK1.01719708
44FGFR30.98715842
45TNK20.98014683
46CSF1R0.96616181
47IRAK10.92888922
48HCK0.92817612
49TRIB30.92611377
50RIPK10.92288425
51PDK10.90287289
52ARAF0.88894008
53EIF2AK20.88801750
54MATK0.88769674
55TRPM70.87400518
56LCK0.86614477
57FGR0.86156420
58SIK10.83808098
59LYN0.82821284
60STK40.81377585
61TAOK30.81357551
62MAP3K30.78851679
63GRK60.77807347
64EPHA20.76994151
65BTK0.76085779
66NME20.75772422
67PRKCD0.74396837
68PTK60.69784838
69KSR20.68686861
70DAPK20.66734394
71PRKG20.66422216
72TEC0.66368289
73MARK30.65864518
74MAP3K50.65408743
75ABL10.64368771
76CAMK1D0.63732949
77EGFR0.62234585
78TESK20.62151932
79YES10.61530172
80STK30.61418722
81ERBB30.61118017
82MAPK150.59908816
83IRAK20.59831438
84MARK20.59021285
85MAP2K60.58914196
86STK240.58052713
87TYRO30.57745504
88GRK70.57051682
89SIK30.56674623
90MOS0.56161710
91PKN10.55028555
92MAPKAPK20.53916617
93RPS6KC10.51411934
94RPS6KL10.51411934
95RPS6KA20.50965053
96PRKD20.50529354
97LRRK20.48311578
98MAPK70.47718693
99TESK10.47025426
100PRKCQ0.46971290
101HIPK20.45476058
102STK380.45337208
103CAMKK20.45242468
104STK100.45019028
105MAP3K10.44980972
106BCR0.44591956
107NUAK10.43832993
108ICK0.42342301
109PAK40.41456284
110INSRR0.39000971
111FYN0.38955571
112NLK0.37691887
113MAP3K20.35260692
114PDK20.34988696
115MAP2K30.34364604
116MAPK120.34222584
117BMPR1B0.33869175
118TTN0.33138954
119DAPK30.33118390
120CDK60.32473196
121FLT30.30031833
122MAP3K110.29981677
123PRKAA20.29909567
124GSK3A0.29905742
125ADRBK20.29510759
126DYRK1B0.29246738
127RPS6KA50.28970908
128PDGFRB0.28681413
129SIK20.25626797
130PIK3CG0.25043158
131IGF1R0.24370215
132PRKCE0.24126182
133RPS6KA60.24014036
134RPS6KA10.24002641
135EPHB20.23222239

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.30598322
2Leishmaniasis_Homo sapiens_hsa051403.26161133
3Allograft rejection_Homo sapiens_hsa053303.20275839
4Toll-like receptor signaling pathway_Homo sapiens_hsa046202.89988958
5Staphylococcus aureus infection_Homo sapiens_hsa051502.89340609
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.85176942
7Legionellosis_Homo sapiens_hsa051342.52489838
8NOD-like receptor signaling pathway_Homo sapiens_hsa046212.51475402
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.47226417
10Pertussis_Homo sapiens_hsa051332.33258347
11Osteoclast differentiation_Homo sapiens_hsa043802.32284335
12TNF signaling pathway_Homo sapiens_hsa046682.24288540
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.24228375
14Intestinal immune network for IgA production_Homo sapiens_hsa046722.16673535
15Measles_Homo sapiens_hsa051622.09733517
16Malaria_Homo sapiens_hsa051442.08795588
17Type I diabetes mellitus_Homo sapiens_hsa049402.04119088
18Rheumatoid arthritis_Homo sapiens_hsa053232.02229367
19Tuberculosis_Homo sapiens_hsa051521.96972326
20Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.95113070
21Toxoplasmosis_Homo sapiens_hsa051451.86981575
22Influenza A_Homo sapiens_hsa051641.85563164
23African trypanosomiasis_Homo sapiens_hsa051431.72990815
24Asthma_Homo sapiens_hsa053101.69857672
25Autoimmune thyroid disease_Homo sapiens_hsa053201.68069092
26Salmonella infection_Homo sapiens_hsa051321.63458406
27Herpes simplex infection_Homo sapiens_hsa051681.56778081
28Apoptosis_Homo sapiens_hsa042101.56098531
29* Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.51762958
30Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.49959969
31Lysosome_Homo sapiens_hsa041421.48463427
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.47406541
33* Chemokine signaling pathway_Homo sapiens_hsa040621.39719455
34B cell receptor signaling pathway_Homo sapiens_hsa046621.38906237
35Antigen processing and presentation_Homo sapiens_hsa046121.38206964
36Phagosome_Homo sapiens_hsa041451.37038023
37Viral myocarditis_Homo sapiens_hsa054161.29826879
38Shigellosis_Homo sapiens_hsa051311.28296612
39Hematopoietic cell lineage_Homo sapiens_hsa046401.25057026
40Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.09600237
41Hepatitis C_Homo sapiens_hsa051601.09209587
42AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.07350508
43Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.04787492
44Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.00822718
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.98356543
46Hepatitis B_Homo sapiens_hsa051610.97304852
47Amoebiasis_Homo sapiens_hsa051460.95565275
48Prion diseases_Homo sapiens_hsa050200.92155753
49Primary immunodeficiency_Homo sapiens_hsa053400.87650004
50Other glycan degradation_Homo sapiens_hsa005110.86533148
51Leukocyte transendothelial migration_Homo sapiens_hsa046700.84618752
52Prolactin signaling pathway_Homo sapiens_hsa049170.84081857
53PPAR signaling pathway_Homo sapiens_hsa033200.78334203
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78232739
55Glycosaminoglycan degradation_Homo sapiens_hsa005310.77458717
56Sphingolipid metabolism_Homo sapiens_hsa006000.75181690
57Bladder cancer_Homo sapiens_hsa052190.74977034
58Small cell lung cancer_Homo sapiens_hsa052220.73264704
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.72617731
60Complement and coagulation cascades_Homo sapiens_hsa046100.72567357
61Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.72368380
62Acute myeloid leukemia_Homo sapiens_hsa052210.71212631
63T cell receptor signaling pathway_Homo sapiens_hsa046600.69619953
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.68153491
65Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.63076913
66Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59461089
67Chronic myeloid leukemia_Homo sapiens_hsa052200.58757707
68Galactose metabolism_Homo sapiens_hsa000520.57359085
69Epstein-Barr virus infection_Homo sapiens_hsa051690.56798767
70Fatty acid biosynthesis_Homo sapiens_hsa000610.56429844
71Mineral absorption_Homo sapiens_hsa049780.55366298
72Transcriptional misregulation in cancer_Homo sapiens_hsa052020.54641619
73Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.51820927
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49009656
75Pancreatic cancer_Homo sapiens_hsa052120.48604752
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46514530
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.44981621
78HIF-1 signaling pathway_Homo sapiens_hsa040660.44457097
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.44437322
80Carbohydrate digestion and absorption_Homo sapiens_hsa049730.44373032
81Platelet activation_Homo sapiens_hsa046110.44137684
82Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.43479739
83Histidine metabolism_Homo sapiens_hsa003400.41973511
84Vibrio cholerae infection_Homo sapiens_hsa051100.41741678
85Proteoglycans in cancer_Homo sapiens_hsa052050.40783269
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40255340
87Type II diabetes mellitus_Homo sapiens_hsa049300.39202993
88Arachidonic acid metabolism_Homo sapiens_hsa005900.38213601
89Renin-angiotensin system_Homo sapiens_hsa046140.37721442
90Fructose and mannose metabolism_Homo sapiens_hsa000510.35581447
91Sulfur metabolism_Homo sapiens_hsa009200.35247466
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.35063768
93Renal cell carcinoma_Homo sapiens_hsa052110.35031482
94Viral carcinogenesis_Homo sapiens_hsa052030.34748057
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.33407542
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.30303176
97Adherens junction_Homo sapiens_hsa045200.30250149
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.30085570
99HTLV-I infection_Homo sapiens_hsa051660.30048476
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.28756781
101ABC transporters_Homo sapiens_hsa020100.27515405
102Insulin resistance_Homo sapiens_hsa049310.27310796
103Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.26743261
104p53 signaling pathway_Homo sapiens_hsa041150.26060516
105Tryptophan metabolism_Homo sapiens_hsa003800.24327022
106GnRH signaling pathway_Homo sapiens_hsa049120.21898477
107Endocytosis_Homo sapiens_hsa041440.21220890
108FoxO signaling pathway_Homo sapiens_hsa040680.20971451
109MicroRNAs in cancer_Homo sapiens_hsa052060.20669073
110Dorso-ventral axis formation_Homo sapiens_hsa043200.20586625
111Collecting duct acid secretion_Homo sapiens_hsa049660.20375932
112Pentose and glucuronate interconversions_Homo sapiens_hsa000400.20321601
113Focal adhesion_Homo sapiens_hsa045100.18427612
114VEGF signaling pathway_Homo sapiens_hsa043700.17905632
115MAPK signaling pathway_Homo sapiens_hsa040100.17314246
116Notch signaling pathway_Homo sapiens_hsa043300.16308101
117Prostate cancer_Homo sapiens_hsa052150.14027117
118Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.13050350
119Phenylalanine metabolism_Homo sapiens_hsa003600.12848447
120Caffeine metabolism_Homo sapiens_hsa002320.12734077

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