

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of transforming growth factor beta1 production (GO:0032908) | 5.27579478 |
| 2 | cell adhesion mediated by integrin (GO:0033627) | 5.24328724 |
| 3 | pericardium development (GO:0060039) | 5.13512782 |
| 4 | peptidyl-proline hydroxylation (GO:0019511) | 5.12748350 |
| 5 | regulation of transmission of nerve impulse (GO:0051969) | 5.02717890 |
| 6 | positive regulation of astrocyte differentiation (GO:0048711) | 4.91506294 |
| 7 | skin morphogenesis (GO:0043589) | 4.83621930 |
| 8 | positive regulation of p38MAPK cascade (GO:1900745) | 4.64776952 |
| 9 | protein heterotrimerization (GO:0070208) | 4.61827566 |
| 10 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 4.46158177 |
| 11 | protein hydroxylation (GO:0018126) | 4.39725086 |
| 12 | positive regulation of chemokine secretion (GO:0090197) | 4.38691428 |
| 13 | positive regulation of macrophage activation (GO:0043032) | 4.36471616 |
| 14 | interleukin-6-mediated signaling pathway (GO:0070102) | 4.34128405 |
| 15 | regulation of plasminogen activation (GO:0010755) | 4.32900322 |
| 16 | positive regulation of neurological system process (GO:0031646) | 4.29249390 |
| 17 | regulation of chemokine secretion (GO:0090196) | 4.26290592 |
| 18 | positive regulation of type 2 immune response (GO:0002830) | 4.25754651 |
| 19 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 4.22898771 |
| 20 | regulation of vascular endothelial growth factor production (GO:0010574) | 4.21935013 |
| 21 | chondrocyte proliferation (GO:0035988) | 4.21418965 |
| 22 | regulation of immunoglobulin secretion (GO:0051023) | 4.12406001 |
| 23 | negative regulation of smooth muscle cell migration (GO:0014912) | 3.97040410 |
| 24 | endodermal cell differentiation (GO:0035987) | 3.94580670 |
| 25 | positive regulation of osteoblast proliferation (GO:0033690) | 3.93153705 |
| 26 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.91349413 |
| 27 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.64105171 |
| 28 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.63522323 |
| 29 | substrate-dependent cell migration (GO:0006929) | 3.62459197 |
| 30 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 3.61121380 |
| 31 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 3.54982389 |
| 32 | wound healing, spreading of epidermal cells (GO:0035313) | 3.52584878 |
| 33 | extracellular fibril organization (GO:0043206) | 3.51425281 |
| 34 | collagen fibril organization (GO:0030199) | 3.49241056 |
| 35 | regulation of transforming growth factor beta production (GO:0071634) | 3.37196389 |
| 36 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.36140061 |
| 37 | chronic inflammatory response (GO:0002544) | 3.34407572 |
| 38 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.34274060 |
| 39 | response to peptidoglycan (GO:0032494) | 3.32925136 |
| 40 | hypotonic response (GO:0006971) | 3.31967489 |
| 41 | collagen metabolic process (GO:0032963) | 3.27499984 |
| 42 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.22102048 |
| 43 | regulation of collagen metabolic process (GO:0010712) | 3.20854861 |
| 44 | fibrinolysis (GO:0042730) | 3.20587109 |
| 45 | regulation of mononuclear cell migration (GO:0071675) | 3.20350638 |
| 46 | collagen catabolic process (GO:0030574) | 3.19596802 |
| 47 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.18107515 |
| 48 | negative regulation of fibrinolysis (GO:0051918) | 3.17949684 |
| 49 | positive regulation of transforming growth factor beta production (GO:0071636) | 3.17779034 |
| 50 | regulation of extracellular matrix disassembly (GO:0010715) | 3.16930167 |
| 51 | cellular response to interleukin-6 (GO:0071354) | 3.15245112 |
| 52 | venous blood vessel morphogenesis (GO:0048845) | 3.13542494 |
| 53 | diterpenoid biosynthetic process (GO:0016102) | 3.13297512 |
| 54 | hyaluronan catabolic process (GO:0030214) | 3.13134759 |
| 55 | regulation of apoptotic cell clearance (GO:2000425) | 3.12372451 |
| 56 | negative regulation of leukocyte chemotaxis (GO:0002689) | 3.12353193 |
| 57 | fibril organization (GO:0097435) | 3.11466191 |
| 58 | glial cell migration (GO:0008347) | 3.10289318 |
| 59 | regulation of collagen biosynthetic process (GO:0032965) | 3.09324176 |
| 60 | positive regulation vascular endothelial growth factor production (GO:0010575) | 3.08745433 |
| 61 | 4-hydroxyproline metabolic process (GO:0019471) | 3.08353667 |
| 62 | regulation of chemokine biosynthetic process (GO:0045073) | 3.07641790 |
| 63 | COPI coating of Golgi vesicle (GO:0048205) | 3.07492552 |
| 64 | Golgi transport vesicle coating (GO:0048200) | 3.07492552 |
| 65 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.06972954 |
| 66 | nucleotide-sugar biosynthetic process (GO:0009226) | 3.06871276 |
| 67 | multicellular organismal macromolecule metabolic process (GO:0044259) | 3.04128775 |
| 68 | mesodermal cell differentiation (GO:0048333) | 3.02504284 |
| 69 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 3.00218933 |
| 70 | multicellular organismal catabolic process (GO:0044243) | 2.99638290 |
| 71 | negative regulation of lipid storage (GO:0010888) | 2.98078026 |
| 72 | multicellular organismal metabolic process (GO:0044236) | 2.90911175 |
| 73 | extracellular matrix disassembly (GO:0022617) | 2.89288171 |
| 74 | lung lobe morphogenesis (GO:0060463) | 2.87849303 |
| 75 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 2.86240028 |
| 76 | protein retention in ER lumen (GO:0006621) | 2.84151260 |
| 77 | wound healing, spreading of cells (GO:0044319) | 2.79545076 |
| 78 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.77884287 |
| 79 | regulation of p38MAPK cascade (GO:1900744) | 2.77537448 |
| 80 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.77535285 |
| 81 | regulation of osteoblast proliferation (GO:0033688) | 2.75963915 |
| 82 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.72378304 |
| 83 | regulation of interleukin-8 secretion (GO:2000482) | 2.70954060 |
| 84 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.69188423 |
| 85 | negative regulation of coagulation (GO:0050819) | 2.67923494 |
| 86 | COPII vesicle coating (GO:0048208) | 2.66790790 |
| 87 | regulation of macrophage chemotaxis (GO:0010758) | 2.65112787 |
| 88 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.64700286 |
| 89 | regulation of monocyte chemotaxis (GO:0090025) | 2.61533149 |
| 90 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.57862400 |
| 91 | blood vessel maturation (GO:0001955) | 2.56080686 |
| 92 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.54887277 |
| 93 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.54237706 |
| 94 | cellular response to zinc ion (GO:0071294) | 2.53764521 |
| 95 | regulation of type 2 immune response (GO:0002828) | 2.51154774 |
| 96 | positive regulation of actin cytoskeleton reorganization (GO:2000251) | 2.50546038 |
| 97 | regulation of fibrinolysis (GO:0051917) | 2.49399642 |
| 98 | regulation of glucocorticoid metabolic process (GO:0031943) | 2.49379637 |
| 99 | cyclooxygenase pathway (GO:0019371) | 2.48842968 |
| 100 | defense response to Gram-negative bacterium (GO:0050829) | 2.48002195 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 6.47112782 |
| 2 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 5.01750397 |
| 3 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.42651232 |
| 4 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.18334250 |
| 5 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.03020060 |
| 6 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 3.02456526 |
| 7 | CJUN_26792858_Chip-Seq_BT549_Human | 2.94463373 |
| 8 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.74845827 |
| 9 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.61945169 |
| 10 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.53288449 |
| 11 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.50303065 |
| 12 | BRD4_25478319_ChIP-Seq_HGPS_Human | 2.46499696 |
| 13 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.45157135 |
| 14 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.42575067 |
| 15 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.32221985 |
| 16 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.27331495 |
| 17 | TP53_16413492_ChIP-PET_HCT116_Human | 2.19663875 |
| 18 | * SOX2_20726797_ChIP-Seq_SW620_Human | 2.17107946 |
| 19 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.16629070 |
| 20 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 2.14941972 |
| 21 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.11134107 |
| 22 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 2.10882775 |
| 23 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 2.10882775 |
| 24 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.01207875 |
| 25 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.98752200 |
| 26 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.96951197 |
| 27 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.93564093 |
| 28 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.93564093 |
| 29 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.93561713 |
| 30 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.93365942 |
| 31 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.87142149 |
| 32 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.85734909 |
| 33 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.79776439 |
| 34 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.79675171 |
| 35 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.77525583 |
| 36 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.72218824 |
| 37 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.68934134 |
| 38 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.65209825 |
| 39 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.61487271 |
| 40 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.55978544 |
| 41 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.51897852 |
| 42 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.46785804 |
| 43 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.43838984 |
| 44 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.43632106 |
| 45 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.43331091 |
| 46 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.43307501 |
| 47 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.37180905 |
| 48 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.30352832 |
| 49 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.27826312 |
| 50 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.27010608 |
| 51 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.26253155 |
| 52 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.25979831 |
| 53 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.18755941 |
| 54 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.16978611 |
| 55 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.16936836 |
| 56 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.16849133 |
| 57 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.16712019 |
| 58 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.15167099 |
| 59 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.14852607 |
| 60 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.11993249 |
| 61 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10936725 |
| 62 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.06680703 |
| 63 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.05564781 |
| 64 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.04278091 |
| 65 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.04243133 |
| 66 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.03607364 |
| 67 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.02710212 |
| 68 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.00724009 |
| 69 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.98959068 |
| 70 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.95900005 |
| 71 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.94248718 |
| 72 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.93277405 |
| 73 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92589456 |
| 74 | * CDX2_22108803_ChIP-Seq_LS180_Human | 0.90471114 |
| 75 | ATF3_27146783_Chip-Seq_COLON_Human | 0.90054960 |
| 76 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.89873622 |
| 77 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.88920965 |
| 78 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.86523828 |
| 79 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.86161912 |
| 80 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.85423486 |
| 81 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.85415055 |
| 82 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.83290245 |
| 83 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.82107361 |
| 84 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.81699208 |
| 85 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.79425587 |
| 86 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.79195887 |
| 87 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.78987759 |
| 88 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.78859845 |
| 89 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.78686946 |
| 90 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.77926984 |
| 91 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.77261406 |
| 92 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.76882608 |
| 93 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.75824340 |
| 94 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.75824340 |
| 95 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.73883626 |
| 96 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.72519210 |
| 97 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.72254494 |
| 98 | PPARD_21283829_ChIP-Seq_MYOFIBROBLAST_Human | 0.71328814 |
| 99 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.70859748 |
| 100 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.70074476 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008438_abnormal_cutaneous_collagen | 8.01765571 |
| 2 | MP0003300_gastrointestinal_ulcer | 4.20588066 |
| 3 | MP0008004_abnormal_stomach_pH | 4.02579276 |
| 4 | MP0004272_abnormal_basement_membrane | 3.84559040 |
| 5 | MP0005275_abnormal_skin_tensile | 3.40300400 |
| 6 | MP0003279_aneurysm | 3.24946153 |
| 7 | MP0003705_abnormal_hypodermis_morpholog | 3.18185286 |
| 8 | MP0005023_abnormal_wound_healing | 2.96965912 |
| 9 | MP0010386_abnormal_urinary_bladder | 2.75562593 |
| 10 | MP0005623_abnormal_meninges_morphology | 2.72787298 |
| 11 | MP0001958_emphysema | 2.72489890 |
| 12 | MP0005503_abnormal_tendon_morphology | 2.46670359 |
| 13 | MP0010352_gastrointestinal_tract_polyps | 2.29108598 |
| 14 | MP0005257_abnormal_intraocular_pressure | 2.20946015 |
| 15 | MP0003950_abnormal_plasma_membrane | 2.20813181 |
| 16 | MP0006082_CNS_inflammation | 2.08002606 |
| 17 | MP0009840_abnormal_foam_cell | 2.02251363 |
| 18 | MP0010368_abnormal_lymphatic_system | 1.87130646 |
| 19 | MP0003566_abnormal_cell_adhesion | 1.75371603 |
| 20 | MP0000343_altered_response_to | 1.74246736 |
| 21 | MP0002060_abnormal_skin_morphology | 1.73609512 |
| 22 | MP0009384_cardiac_valve_regurgitation | 1.71474086 |
| 23 | MP0002132_abnormal_respiratory_system | 1.69549080 |
| 24 | MP0006054_spinal_hemorrhage | 1.63737283 |
| 25 | MP0005164_abnormal_response_to | 1.60375191 |
| 26 | MP0003724_increased_susceptibility_to | 1.58513757 |
| 27 | MP0003091_abnormal_cell_migration | 1.58477603 |
| 28 | MP0004233_abnormal_muscle_weight | 1.54018896 |
| 29 | MP0005166_decreased_susceptibility_to | 1.40001334 |
| 30 | MP0005508_abnormal_skeleton_morphology | 1.39168854 |
| 31 | MP0003436_decreased_susceptibility_to | 1.37798299 |
| 32 | MP0002295_abnormal_pulmonary_circulatio | 1.37218388 |
| 33 | MP0009785_altered_susceptibility_to | 1.33516088 |
| 34 | MP0002168_other_aberrant_phenotype | 1.30392345 |
| 35 | MP0002933_joint_inflammation | 1.28314716 |
| 36 | MP0000462_abnormal_digestive_system | 1.27596020 |
| 37 | MP0009764_decreased_sensitivity_to | 1.23865399 |
| 38 | MP0002138_abnormal_hepatobiliary_system | 1.23862498 |
| 39 | MP0001533_abnormal_skeleton_physiology | 1.21493534 |
| 40 | MP0000767_abnormal_smooth_muscle | 1.21049780 |
| 41 | MP0001542_abnormal_bone_strength | 1.20504387 |
| 42 | MP0003448_altered_tumor_morphology | 1.19660518 |
| 43 | MP0002998_abnormal_bone_remodeling | 1.19427081 |
| 44 | MP0002896_abnormal_bone_mineralization | 1.18077576 |
| 45 | MP0009250_abnormal_appendicular_skeleto | 1.17854208 |
| 46 | MP0005390_skeleton_phenotype | 1.17178795 |
| 47 | MP0003191_abnormal_cellular_cholesterol | 1.15038847 |
| 48 | MP0002006_tumorigenesis | 1.15033426 |
| 49 | MP0002148_abnormal_hypersensitivity_rea | 1.13920830 |
| 50 | MP0000249_abnormal_blood_vessel | 1.13296307 |
| 51 | MP0001879_abnormal_lymphatic_vessel | 1.11902222 |
| 52 | MP0002163_abnormal_gland_morphology | 1.09141671 |
| 53 | MP0000013_abnormal_adipose_tissue | 1.08501538 |
| 54 | MP0005595_abnormal_vascular_smooth | 1.06844511 |
| 55 | MP0002332_abnormal_exercise_endurance | 1.04170057 |
| 56 | MP0003941_abnormal_skin_development | 1.03568621 |
| 57 | MP0000858_altered_metastatic_potential | 1.02572212 |
| 58 | MP0002089_abnormal_postnatal_growth/wei | 0.97863653 |
| 59 | MP0005171_absent_coat_pigmentation | 0.97776809 |
| 60 | MP0003828_pulmonary_edema | 0.96538735 |
| 61 | MP0000613_abnormal_salivary_gland | 0.90847114 |
| 62 | MP0005197_abnormal_uvea_morphology | 0.90260173 |
| 63 | MP0004134_abnormal_chest_morphology | 0.87767862 |
| 64 | MP0009780_abnormal_chondrocyte_physiolo | 0.86654675 |
| 65 | MP0005165_increased_susceptibility_to | 0.86634322 |
| 66 | MP0005084_abnormal_gallbladder_morpholo | 0.85099378 |
| 67 | MP0004858_abnormal_nervous_system | 0.83958074 |
| 68 | MP0002277_abnormal_respiratory_mucosa | 0.83505242 |
| 69 | MP0001614_abnormal_blood_vessel | 0.82026446 |
| 70 | MP0005388_respiratory_system_phenotype | 0.80274640 |
| 71 | MP0002133_abnormal_respiratory_system | 0.80274640 |
| 72 | MP0000163_abnormal_cartilage_morphology | 0.78507155 |
| 73 | MP0001243_abnormal_dermal_layer | 0.77810561 |
| 74 | MP0004510_myositis | 0.75609237 |
| 75 | MP0003045_fibrosis | 0.75565269 |
| 76 | MP0002282_abnormal_trachea_morphology | 0.74903114 |
| 77 | MP0000750_abnormal_muscle_regeneration | 0.72632603 |
| 78 | MP0002405_respiratory_system_inflammati | 0.72242939 |
| 79 | MP0002877_abnormal_melanocyte_morpholog | 0.70877630 |
| 80 | MP0004947_skin_inflammation | 0.70807229 |
| 81 | MP0001853_heart_inflammation | 0.70589005 |
| 82 | MP0004084_abnormal_cardiac_muscle | 0.69793932 |
| 83 | MP0002113_abnormal_skeleton_development | 0.68853413 |
| 84 | MP0003453_abnormal_keratinocyte_physiol | 0.68842689 |
| 85 | MP0003075_altered_response_to | 0.68335546 |
| 86 | MP0003795_abnormal_bone_structure | 0.67634174 |
| 87 | MP0002419_abnormal_innate_immunity | 0.67597164 |
| 88 | MP0009765_abnormal_xenobiotic_induced | 0.63652670 |
| 89 | MP0002128_abnormal_blood_circulation | 0.61940858 |
| 90 | MP0001915_intracranial_hemorrhage | 0.61742386 |
| 91 | MP0002925_abnormal_cardiovascular_devel | 0.61445025 |
| 92 | MP0010155_abnormal_intestine_physiology | 0.61163703 |
| 93 | MP0000733_abnormal_muscle_development | 0.60123586 |
| 94 | MP0001299_abnormal_eye_distance/ | 0.59221303 |
| 95 | MP0001845_abnormal_inflammatory_respons | 0.58633641 |
| 96 | MP0003252_abnormal_bile_duct | 0.58355827 |
| 97 | MP0010771_integument_phenotype | 0.58128356 |
| 98 | MP0001501_abnormal_sleep_pattern | 0.57216043 |
| 99 | MP0005395_other_phenotype | 0.56577168 |
| 100 | MP0003690_abnormal_glial_cell | 0.56471824 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protrusio acetabuli (HP:0003179) | 8.38844408 |
| 2 | Premature rupture of membranes (HP:0001788) | 7.94975745 |
| 3 | Aortic dissection (HP:0002647) | 6.57651959 |
| 4 | Arterial tortuosity (HP:0005116) | 5.65064315 |
| 5 | Vascular tortuosity (HP:0004948) | 5.38154041 |
| 6 | Spondylolisthesis (HP:0003302) | 4.91425563 |
| 7 | Aortic aneurysm (HP:0004942) | 4.81215502 |
| 8 | Soft skin (HP:0000977) | 4.59527665 |
| 9 | Follicular hyperkeratosis (HP:0007502) | 4.29273301 |
| 10 | Abnormality of dentin (HP:0010299) | 4.25571383 |
| 11 | Abnormality of proline metabolism (HP:0010907) | 4.19037874 |
| 12 | Hydroxyprolinuria (HP:0003080) | 4.19037874 |
| 13 | Atrophic scars (HP:0001075) | 3.96888347 |
| 14 | Broad metatarsal (HP:0001783) | 3.95585592 |
| 15 | Wormian bones (HP:0002645) | 3.74720305 |
| 16 | Vertebral compression fractures (HP:0002953) | 3.59841803 |
| 17 | Cervical subluxation (HP:0003308) | 3.52170939 |
| 18 | Neonatal short-limb short stature (HP:0008921) | 3.51325725 |
| 19 | Ankle contracture (HP:0006466) | 3.47746156 |
| 20 | Mitral stenosis (HP:0001718) | 3.46391955 |
| 21 | Fragile skin (HP:0001030) | 3.43483562 |
| 22 | Blue sclerae (HP:0000592) | 3.40740925 |
| 23 | Overgrowth (HP:0001548) | 3.40650920 |
| 24 | Genu recurvatum (HP:0002816) | 3.28710174 |
| 25 | Mitral valve prolapse (HP:0001634) | 3.28418308 |
| 26 | Bladder diverticulum (HP:0000015) | 3.27279236 |
| 27 | Dilatation of the ascending aorta (HP:0005111) | 3.19716920 |
| 28 | Peritonitis (HP:0002586) | 3.18495569 |
| 29 | Cardiovascular calcification (HP:0011915) | 3.12906297 |
| 30 | Ileus (HP:0002595) | 3.05239720 |
| 31 | Hyperextensible skin (HP:0000974) | 3.01427424 |
| 32 | Rectal prolapse (HP:0002035) | 2.79732965 |
| 33 | Biconcave vertebral bodies (HP:0004586) | 2.79070589 |
| 34 | Male infertility (HP:0003251) | 2.79059917 |
| 35 | Joint laxity (HP:0001388) | 2.74620254 |
| 36 | Aortic regurgitation (HP:0001659) | 2.74534128 |
| 37 | Type 1 muscle fiber predominance (HP:0003803) | 2.73794987 |
| 38 | Femoral bowing (HP:0002980) | 2.73373954 |
| 39 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.70440709 |
| 40 | Shallow orbits (HP:0000586) | 2.69246975 |
| 41 | Ankyloglossia (HP:0010296) | 2.66907368 |
| 42 | Spinal rigidity (HP:0003306) | 2.64194181 |
| 43 | Thin bony cortex (HP:0002753) | 2.64082461 |
| 44 | Abnormality of the acetabulum (HP:0003170) | 2.59618080 |
| 45 | Cerebral aneurysm (HP:0004944) | 2.56586096 |
| 46 | Elbow flexion contracture (HP:0002987) | 2.56570740 |
| 47 | Striae distensae (HP:0001065) | 2.52338020 |
| 48 | Tetraparesis (HP:0002273) | 2.49101698 |
| 49 | Round ear (HP:0100830) | 2.48288112 |
| 50 | Knee flexion contracture (HP:0006380) | 2.42763808 |
| 51 | Pterygium (HP:0001059) | 2.38966033 |
| 52 | Slender build (HP:0001533) | 2.36399657 |
| 53 | Glomerulonephritis (HP:0000099) | 2.29203248 |
| 54 | Disproportionate tall stature (HP:0001519) | 2.28327841 |
| 55 | Aneurysm (HP:0002617) | 2.25248849 |
| 56 | Inguinal hernia (HP:0000023) | 2.20513927 |
| 57 | Ectopia lentis (HP:0001083) | 2.20395265 |
| 58 | Joint stiffness (HP:0001387) | 2.18657125 |
| 59 | Pectus carinatum (HP:0000768) | 2.17121670 |
| 60 | Hypoplasia of the iris (HP:0007676) | 2.16775337 |
| 61 | Abnormality of the right ventricle (HP:0001707) | 2.15495422 |
| 62 | Abnormal delivery (HP:0001787) | 2.15264337 |
| 63 | Abnormality of oral frenula (HP:0000190) | 2.13062274 |
| 64 | Congenital glaucoma (HP:0001087) | 2.11399846 |
| 65 | Wrist flexion contracture (HP:0001239) | 2.10049691 |
| 66 | Coxa vara (HP:0002812) | 2.08076765 |
| 67 | Mitral regurgitation (HP:0001653) | 2.07811336 |
| 68 | Aortic valve stenosis (HP:0001650) | 2.07083702 |
| 69 | Thoracolumbar scoliosis (HP:0002944) | 2.06329498 |
| 70 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.03988306 |
| 71 | Recurrent corneal erosions (HP:0000495) | 2.03452768 |
| 72 | Osteolytic defects of the hand bones (HP:0009699) | 2.02111156 |
| 73 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.02111156 |
| 74 | Pulmonic stenosis (HP:0001642) | 2.01562004 |
| 75 | Hand muscle atrophy (HP:0009130) | 2.00686547 |
| 76 | Broad ribs (HP:0000885) | 1.99079876 |
| 77 | Corneal dystrophy (HP:0001131) | 1.99077449 |
| 78 | Ovoid vertebral bodies (HP:0003300) | 1.97675306 |
| 79 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.97184188 |
| 80 | Nephritis (HP:0000123) | 1.94744745 |
| 81 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.89480611 |
| 82 | Mucopolysacchariduria (HP:0008155) | 1.89480611 |
| 83 | Upper limb amyotrophy (HP:0009129) | 1.89378114 |
| 84 | Distal upper limb amyotrophy (HP:0007149) | 1.89378114 |
| 85 | Short nail (HP:0001799) | 1.88879678 |
| 86 | Abnormality of the nasal mucosa (HP:0000433) | 1.87375916 |
| 87 | Exocrine pancreatic insufficiency (HP:0001738) | 1.86885443 |
| 88 | Menorrhagia (HP:0000132) | 1.86466125 |
| 89 | Hypoventilation (HP:0002791) | 1.86125497 |
| 90 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.84415695 |
| 91 | Increased corneal curvature (HP:0100692) | 1.82679863 |
| 92 | Keratoconus (HP:0000563) | 1.82679863 |
| 93 | Abnormality of the anterior chamber (HP:0000593) | 1.80969431 |
| 94 | Severe short stature (HP:0003510) | 1.80817344 |
| 95 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.80002370 |
| 96 | Osteopenia (HP:0000938) | 1.79235204 |
| 97 | Alopecia of scalp (HP:0002293) | 1.77317457 |
| 98 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.77237524 |
| 99 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.73790014 |
| 100 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.73790014 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LMTK2 | 8.67359697 |
| 2 | TGFBR2 | 3.55594782 |
| 3 | LATS2 | 3.46447879 |
| 4 | STK38L | 3.08852446 |
| 5 | STK24 | 2.89777864 |
| 6 | PRKG2 | 2.65897516 |
| 7 | EPHB2 | 2.59327826 |
| 8 | MAP3K12 | 2.51806300 |
| 9 | ERN1 | 2.35745790 |
| 10 | MYLK | 2.19147659 |
| 11 | PTK2 | 2.06034215 |
| 12 | NEK9 | 1.99791738 |
| 13 | NTRK1 | 1.93555329 |
| 14 | PDGFRA | 1.93412632 |
| 15 | DDR2 | 1.82897203 |
| 16 | PAK4 | 1.59224539 |
| 17 | ARAF | 1.52431075 |
| 18 | MST4 | 1.51108498 |
| 19 | EPHA2 | 1.49872580 |
| 20 | STK38 | 1.40045753 |
| 21 | MET | 1.36963000 |
| 22 | TEC | 1.33690252 |
| 23 | BCR | 1.31845846 |
| 24 | IRAK3 | 1.31739189 |
| 25 | STK3 | 1.31157154 |
| 26 | MAP3K13 | 1.24410665 |
| 27 | MST1R | 1.24142445 |
| 28 | BMPR2 | 1.21763728 |
| 29 | FLT3 | 1.20456513 |
| 30 | CDK8 | 1.20406891 |
| 31 | LIMK1 | 1.17842584 |
| 32 | ROCK1 | 1.15538569 |
| 33 | ERBB4 | 1.12871602 |
| 34 | ERBB3 | 1.11480594 |
| 35 | TGFBR1 | 1.04370483 |
| 36 | LATS1 | 1.02188320 |
| 37 | MOS | 1.01032867 |
| 38 | CDC42BPA | 0.98194895 |
| 39 | PAK2 | 0.96863734 |
| 40 | TESK1 | 0.96838860 |
| 41 | TIE1 | 0.96602928 |
| 42 | MAP3K3 | 0.89348226 |
| 43 | JAK1 | 0.88476436 |
| 44 | WNK4 | 0.86760575 |
| 45 | MAP3K9 | 0.86730111 |
| 46 | TRPM7 | 0.83695106 |
| 47 | ZAP70 | 0.82457912 |
| 48 | MELK | 0.81130200 |
| 49 | PDGFRB | 0.80272815 |
| 50 | STK39 | 0.79779024 |
| 51 | TNIK | 0.77687921 |
| 52 | PIK3CA | 0.76022960 |
| 53 | MAPK7 | 0.72851183 |
| 54 | TYK2 | 0.69376383 |
| 55 | WNK1 | 0.65923623 |
| 56 | PLK2 | 0.62648944 |
| 57 | ABL2 | 0.61664952 |
| 58 | PDK2 | 0.61614534 |
| 59 | TTN | 0.60747612 |
| 60 | PRKCE | 0.60577249 |
| 61 | RIPK1 | 0.59380249 |
| 62 | JAK3 | 0.55660893 |
| 63 | PRKD2 | 0.54626888 |
| 64 | AKT3 | 0.52765590 |
| 65 | ROCK2 | 0.52133771 |
| 66 | CLK1 | 0.52021578 |
| 67 | ILK | 0.51651018 |
| 68 | MAPK15 | 0.51540644 |
| 69 | EIF2AK3 | 0.51515088 |
| 70 | TBK1 | 0.49359404 |
| 71 | EPHB1 | 0.45843289 |
| 72 | KSR2 | 0.43319921 |
| 73 | MAP3K2 | 0.42626752 |
| 74 | DAPK3 | 0.41362783 |
| 75 | SIK1 | 0.40602960 |
| 76 | MAP3K6 | 0.40433149 |
| 77 | MAPK11 | 0.39483265 |
| 78 | MAP3K7 | 0.38655442 |
| 79 | MAPKAPK3 | 0.37820389 |
| 80 | TAOK2 | 0.37766004 |
| 81 | GRK1 | 0.36751686 |
| 82 | MAP3K14 | 0.35244978 |
| 83 | PIM2 | 0.35192904 |
| 84 | BRSK2 | 0.33959747 |
| 85 | PRKCD | 0.32110859 |
| 86 | HIPK2 | 0.29833336 |
| 87 | CASK | 0.29407827 |
| 88 | CDK9 | 0.28715281 |
| 89 | PTK2B | 0.28203174 |
| 90 | INSRR | 0.25338741 |
| 91 | KSR1 | 0.25036554 |
| 92 | MAP2K3 | 0.24988351 |
| 93 | MTOR | 0.24835401 |
| 94 | SRC | 0.23683228 |
| 95 | PRKD1 | 0.22987475 |
| 96 | PIK3CG | 0.22586992 |
| 97 | ABL1 | 0.22487015 |
| 98 | MAP3K8 | 0.20853033 |
| 99 | MAP2K1 | 0.20062388 |
| 100 | PDPK1 | 0.19771941 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Malaria_Homo sapiens_hsa05144 | 3.33311671 |
| 2 | Amoebiasis_Homo sapiens_hsa05146 | 2.94780821 |
| 3 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.93564272 |
| 4 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.82765219 |
| 5 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.63703226 |
| 6 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.62049904 |
| 7 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 2.55813383 |
| 8 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.54710523 |
| 9 | Legionellosis_Homo sapiens_hsa05134 | 2.36414187 |
| 10 | * Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.35094722 |
| 11 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.16852470 |
| 12 | Prion diseases_Homo sapiens_hsa05020 | 2.16169883 |
| 13 | Salmonella infection_Homo sapiens_hsa05132 | 2.11753873 |
| 14 | African trypanosomiasis_Homo sapiens_hsa05143 | 2.00374321 |
| 15 | * Pertussis_Homo sapiens_hsa05133 | 1.88136572 |
| 16 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.76398929 |
| 17 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.72631297 |
| 18 | Focal adhesion_Homo sapiens_hsa04510 | 1.67826717 |
| 19 | Bladder cancer_Homo sapiens_hsa05219 | 1.60790828 |
| 20 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.58043788 |
| 21 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.55487779 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.52860539 |
| 23 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.50170159 |
| 24 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.41559191 |
| 25 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.39434038 |
| 26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.37561370 |
| 27 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.30638404 |
| 28 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.28417082 |
| 29 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.27562267 |
| 30 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.26415682 |
| 31 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.24333682 |
| 32 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.21109852 |
| 33 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.14218824 |
| 34 | Shigellosis_Homo sapiens_hsa05131 | 1.11003154 |
| 35 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.09200037 |
| 36 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.08770972 |
| 37 | Influenza A_Homo sapiens_hsa05164 | 1.03099979 |
| 38 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.98484589 |
| 39 | Mineral absorption_Homo sapiens_hsa04978 | 0.96902322 |
| 40 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.92886484 |
| 41 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.92861017 |
| 42 | Adherens junction_Homo sapiens_hsa04520 | 0.92218219 |
| 43 | Hepatitis C_Homo sapiens_hsa05160 | 0.90417830 |
| 44 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.90092698 |
| 45 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.86670244 |
| 46 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.85560550 |
| 47 | Galactose metabolism_Homo sapiens_hsa00052 | 0.84283336 |
| 48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.82138052 |
| 49 | Pathways in cancer_Homo sapiens_hsa05200 | 0.81291914 |
| 50 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.81244244 |
| 51 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.78469506 |
| 52 | Tight junction_Homo sapiens_hsa04530 | 0.78364312 |
| 53 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.76546708 |
| 54 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.75977140 |
| 55 | Leishmaniasis_Homo sapiens_hsa05140 | 0.75295696 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.75294514 |
| 57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75098519 |
| 58 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.74818201 |
| 59 | Phagosome_Homo sapiens_hsa04145 | 0.74564218 |
| 60 | Other glycan degradation_Homo sapiens_hsa00511 | 0.73969787 |
| 61 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.73501603 |
| 62 | Circadian rhythm_Homo sapiens_hsa04710 | 0.72776617 |
| 63 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.69517637 |
| 64 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.68208888 |
| 65 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.66217138 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.64987111 |
| 67 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.64832221 |
| 68 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.64773974 |
| 69 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.62396925 |
| 70 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.62193081 |
| 71 | Protein export_Homo sapiens_hsa03060 | 0.58259413 |
| 72 | Measles_Homo sapiens_hsa05162 | 0.57817222 |
| 73 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.56750948 |
| 74 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.56173605 |
| 75 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.55005386 |
| 76 | Lysosome_Homo sapiens_hsa04142 | 0.54912395 |
| 77 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.54668423 |
| 78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53741289 |
| 79 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.53505867 |
| 80 | Hepatitis B_Homo sapiens_hsa05161 | 0.53032721 |
| 81 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.52256180 |
| 82 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50716344 |
| 83 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48858583 |
| 84 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.47000674 |
| 85 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.46240800 |
| 86 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46113510 |
| 87 | Tuberculosis_Homo sapiens_hsa05152 | 0.45607639 |
| 88 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.43390325 |
| 89 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42936978 |
| 90 | Melanoma_Homo sapiens_hsa05218 | 0.41364439 |
| 91 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.40157911 |
| 92 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.36249931 |
| 93 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.35780563 |
| 94 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.34783156 |
| 95 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33753143 |
| 96 | Platelet activation_Homo sapiens_hsa04611 | 0.32915745 |
| 97 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.32592234 |
| 98 | Thyroid cancer_Homo sapiens_hsa05216 | 0.32160961 |
| 99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.31900383 |
| 100 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.30607659 |

