CXCR6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)9.66094692
2negative T cell selection (GO:0043383)8.38973051
3negative thymic T cell selection (GO:0045060)8.21650945
4regulation of isotype switching to IgG isotypes (GO:0048302)7.30917389
5positive thymic T cell selection (GO:0045059)7.28026186
6cellular response to interleukin-15 (GO:0071350)7.21860941
7positive regulation of gamma-delta T cell activation (GO:0046645)7.06960698
8thymic T cell selection (GO:0045061)6.79528791
9T cell migration (GO:0072678)6.69215050
10regulation of gamma-delta T cell differentiation (GO:0045586)6.46595031
11interferon-gamma production (GO:0032609)6.41822237
12positive T cell selection (GO:0043368)6.39267730
13response to interleukin-15 (GO:0070672)6.30368252
14tolerance induction (GO:0002507)6.26501382
15regulation of T cell tolerance induction (GO:0002664)6.04191606
16T cell selection (GO:0045058)5.88218868
17regulation of gamma-delta T cell activation (GO:0046643)5.84737071
18leukocyte aggregation (GO:0070486)5.82084089
19T cell costimulation (GO:0031295)5.70640853
20lymphocyte costimulation (GO:0031294)5.64565150
21regulation of B cell receptor signaling pathway (GO:0050855)5.59460266
22T cell receptor signaling pathway (GO:0050852)5.55364116
23regulation of lymphocyte chemotaxis (GO:1901623)5.52891827
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.47165130
25positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.37615714
26positive regulation of interleukin-8 secretion (GO:2000484)5.35366402
27negative regulation by host of viral transcription (GO:0043922)5.27686593
28positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.15265342
29positive regulation of alpha-beta T cell proliferation (GO:0046641)5.14629896
30negative regulation of T cell mediated immunity (GO:0002710)5.10827764
31positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)5.05210759
32positive regulation of natural killer cell mediated immunity (GO:0002717)5.05210759
33eosinophil chemotaxis (GO:0048245)5.03516273
34regulation of leukocyte mediated cytotoxicity (GO:0001910)4.98163010
35negative regulation of viral genome replication (GO:0045071)4.96704911
36positive regulation of tolerance induction (GO:0002645)4.96064526
37regulation of T cell mediated cytotoxicity (GO:0001914)4.94598338
38pyrimidine nucleoside catabolic process (GO:0046135)4.92284535
39regulation of natural killer cell mediated immunity (GO:0002715)4.90855445
40regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.90855445
41lymphocyte chemotaxis (GO:0048247)4.89658794
42positive regulation of leukocyte mediated cytotoxicity (GO:0001912)4.83499112
43regulation of interleukin-12 biosynthetic process (GO:0045075)4.81505130
44antigen receptor-mediated signaling pathway (GO:0050851)4.79123012
45antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.72132323
46antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.72132323
47regulation of alpha-beta T cell proliferation (GO:0046640)4.67028575
48regulation of activation of Janus kinase activity (GO:0010533)4.63240088
49regulation of T cell chemotaxis (GO:0010819)4.60555643
50positive regulation of T cell chemotaxis (GO:0010820)4.60555643
51positive regulation of lymphocyte migration (GO:2000403)4.55579079
52eosinophil migration (GO:0072677)4.52606162
53regulation of cell killing (GO:0031341)4.50912677
54positive regulation of monocyte chemotaxis (GO:0090026)4.50082736
55sequestering of actin monomers (GO:0042989)4.49071088
56positive regulation of isotype switching (GO:0045830)4.43488928
57regulation of tolerance induction (GO:0002643)4.39420446
58positive regulation of cell killing (GO:0031343)4.35044017
59regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.31609779
60regulation of isotype switching (GO:0045191)4.28439369
61regulation of T cell receptor signaling pathway (GO:0050856)4.20107401
62regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.19569423
63negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)4.17577273
64positive regulation of calcium-mediated signaling (GO:0050850)4.16998511
65positive regulation of T cell mediated cytotoxicity (GO:0001916)4.16676868
66regulation of B cell differentiation (GO:0045577)4.12218496
67T-helper cell differentiation (GO:0042093)4.11734969
68CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)4.11734969
69antigen processing and presentation of endogenous antigen (GO:0019883)4.11098941
70negative regulation of lymphocyte mediated immunity (GO:0002707)4.10218037
71negative regulation of B cell proliferation (GO:0030889)4.09141146
72macrophage chemotaxis (GO:0048246)4.07736653
73Arp2/3 complex-mediated actin nucleation (GO:0034314)4.07509355
74lymphocyte migration (GO:0072676)4.04269945
75negative regulation of T cell apoptotic process (GO:0070233)4.03996738
76regulation of interleukin-2 biosynthetic process (GO:0045076)4.03800309
77positive regulation of DNA recombination (GO:0045911)4.02646566
78mast cell activation (GO:0045576)3.99591670
79positive regulation of immunoglobulin mediated immune response (GO:0002891)3.93718699
80positive regulation of B cell mediated immunity (GO:0002714)3.93718699
81regulation of chronic inflammatory response (GO:0002676)3.90808013
82leukocyte cell-cell adhesion (GO:0007159)3.90504121
83regulation of immunoglobulin mediated immune response (GO:0002889)3.89144190
84positive regulation of immunoglobulin production (GO:0002639)3.87469212
85negative regulation of T cell receptor signaling pathway (GO:0050860)3.84055859
86regulation of immunoglobulin production (GO:0002637)3.82715926
87dendritic cell chemotaxis (GO:0002407)3.79925114
88cellular defense response (GO:0006968)3.77527772
89regulation of response to tumor cell (GO:0002834)3.76751680
90positive regulation of response to tumor cell (GO:0002836)3.76751680
91positive regulation of immune response to tumor cell (GO:0002839)3.76751680
92regulation of immune response to tumor cell (GO:0002837)3.76751680
93heterotypic cell-cell adhesion (GO:0034113)3.75791374
94regulation of interleukin-8 secretion (GO:2000482)3.74970421
95regulation of B cell mediated immunity (GO:0002712)3.74610019
96alpha-beta T cell activation involved in immune response (GO:0002287)3.73558834
97T cell differentiation involved in immune response (GO:0002292)3.73558834
98alpha-beta T cell differentiation involved in immune response (GO:0002293)3.73558834
99homeostasis of number of cells within a tissue (GO:0048873)3.70744645
100production of molecular mediator involved in inflammatory response (GO:0002532)3.68058685
101B cell receptor signaling pathway (GO:0050853)3.67886052
102T cell differentiation (GO:0030217)3.67820155
103regulation of lymphocyte migration (GO:2000401)3.67250348
104activated T cell proliferation (GO:0050798)3.63455495
105negative regulation of B cell activation (GO:0050869)3.62247853
106positive regulation of T-helper 1 type immune response (GO:0002827)3.60456398
107T cell activation (GO:0042110)3.59851800
108regulation of response to interferon-gamma (GO:0060330)3.59401396
109regulation of viral genome replication (GO:0045069)3.58233193
110regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.54498072
111cytolysis (GO:0019835)3.54356844
112regulation of lymphocyte mediated immunity (GO:0002706)3.53931149
113negative regulation of viral process (GO:0048525)3.48927312
114actin nucleation (GO:0045010)3.48383929
115positive regulation of interleukin-2 production (GO:0032743)3.46653178
116negative regulation of viral transcription (GO:0032897)3.45664159
117positive regulation of lymphocyte mediated immunity (GO:0002708)3.45263355
118positive regulation of B cell differentiation (GO:0045579)3.39609730
119positive regulation of T cell migration (GO:2000406)3.36372549
120regulation of memory T cell differentiation (GO:0043380)3.35391572
121alpha-beta T cell differentiation (GO:0046632)3.33760404
122positive regulation of macrophage differentiation (GO:0045651)3.31983025
123positive regulation of T cell activation (GO:0050870)3.31708352
124regulation of regulatory T cell differentiation (GO:0045589)3.30933887
125negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.28582787
126immune response-activating cell surface receptor signaling pathway (GO:0002429)3.25384874
127positive regulation of alpha-beta T cell activation (GO:0046635)3.22731808
128positive regulation of interferon-gamma production (GO:0032729)3.22499383
129antigen processing and presentation via MHC class Ib (GO:0002475)3.21666312
130positive regulation of interleukin-1 beta secretion (GO:0050718)3.21248456
131positive regulation of defense response to virus by host (GO:0002230)3.21211488
132alpha-beta T cell activation (GO:0046631)3.21089199
133regulation of calcium-mediated signaling (GO:0050848)3.18836917
134dendritic cell migration (GO:0036336)3.11337900
135regulation of T cell migration (GO:2000404)3.09785855
136adaptation of signaling pathway (GO:0023058)3.07782384
137positive regulation of interleukin-1 secretion (GO:0050716)3.02365201
138regulation of interleukin-1 beta secretion (GO:0050706)3.01695235
139regulation of monocyte chemotaxis (GO:0090025)2.94843311
140modulation by host of symbiont transcription (GO:0052472)2.93939088
141modulation by host of viral transcription (GO:0043921)2.93939088
142* chemokine-mediated signaling pathway (GO:0070098)2.92018227
143granulocyte activation (GO:0036230)2.91525875
144cytidine deamination (GO:0009972)11.6392339
145cytidine metabolic process (GO:0046087)11.6392339
146cytidine catabolic process (GO:0006216)11.6392339
147pyrimidine ribonucleoside catabolic process (GO:0046133)10.5003299
148negative regulation of leukocyte mediated cytotoxicity (GO:0001911)10.3659661
149negative regulation of cell killing (GO:0031342)10.3659661
150regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:004509110.2666108

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.27730058
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human7.15508467
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.53800971
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.51244115
5STAT3_20064451_ChIP-Seq_CD4+T_Mouse4.42819266
6* STAT4_19710469_ChIP-ChIP_TH1__Mouse4.35225087
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.96201637
8* RUNX_20019798_ChIP-Seq_JUKART_Human3.78566097
9FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.60013658
10MYB_26560356_Chip-Seq_TH2_Human3.59057843
11IRF8_21731497_ChIP-ChIP_J774_Mouse3.28875860
12MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.18971026
13SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.90323978
14MAF_26560356_Chip-Seq_TH1_Human2.89668601
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.83022574
16* MYB_26560356_Chip-Seq_TH1_Human2.79006645
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.65929064
18UTX_26944678_Chip-Seq_JUKART_Human2.62822129
19MYC_22102868_ChIP-Seq_BL_Human2.33283369
20GATA3_27048872_Chip-Seq_THYMUS_Human2.17500265
21NOTCH1_21737748_ChIP-Seq_TLL_Human2.14300779
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.13732726
23RUNX1_22412390_ChIP-Seq_EML_Mouse2.10829235
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.06790406
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.06725494
26MAF_26560356_Chip-Seq_TH2_Human2.02418701
27SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.97190403
28SMAD_19615063_ChIP-ChIP_OVARY_Human1.95350946
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.93977703
30* IRF8_27001747_Chip-Seq_BMDM_Mouse1.93795805
31SPI1_23547873_ChIP-Seq_NB4_Human1.93695449
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.90276189
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.87827745
34FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.81751457
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.81033450
36E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.77232944
37RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.65806204
38RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.63605980
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.61814450
40MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.57095610
41NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.54143934
42EGR1_19032775_ChIP-ChIP_M12_Human1.49850823
43CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.49421020
44KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.47654785
45GATA3_26560356_Chip-Seq_TH2_Human1.47169888
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.44411042
47LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.43844720
48VDR_21846776_ChIP-Seq_THP-1_Human1.43774493
49VDR_24763502_ChIP-Seq_THP-1_Human1.39696419
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.38199557
51TCF7_22412390_ChIP-Seq_EML_Mouse1.37046826
52BRD4_27068464_Chip-Seq_AML-cells_Mouse1.35255554
53PCGF2_27294783_Chip-Seq_ESCs_Mouse1.29157763
54E2F7_22180533_ChIP-Seq_HELA_Human1.28240115
55SCL_19346495_ChIP-Seq_HPC-7_Human1.26652166
56GATA2_22383799_ChIP-Seq_G1ME_Mouse1.25874245
57LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.24769574
58KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.21832533
59PU_27001747_Chip-Seq_BMDM_Mouse1.21020256
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.20879704
61SPI1_23127762_ChIP-Seq_K562_Human1.20217967
62CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19721960
63PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.19571461
64VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.17113268
65GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.16630474
66CIITA_25753668_ChIP-Seq_RAJI_Human1.15299948
67* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13414161
68PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13207505
69* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.13141875
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11343779
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10395161
72VDR_23849224_ChIP-Seq_CD4+_Human1.09124429
73EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.06900304
74KDM2B_26808549_Chip-Seq_DND41_Human1.05603234
75* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04960565
76* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02307774
77PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01937044
78GATA3_26560356_Chip-Seq_TH1_Human1.00874382
79NFE2_27457419_Chip-Seq_LIVER_Mouse0.99065807
80GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98641161
81SUZ12_27294783_Chip-Seq_NPCs_Mouse0.96726114
82ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96549825
83VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.96056230
84* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94266686
85HOXB4_20404135_ChIP-ChIP_EML_Mouse0.91194554
86SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89562243
87SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.88604350
88VDR_24787735_ChIP-Seq_THP-1_Human0.87962932
89SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84765672
90STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.83878202
91* GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.83568449
92FOXA1_21572438_ChIP-Seq_LNCaP_Human0.81537381
93FOXP3_21729870_ChIP-Seq_TREG_Human0.81128700
94TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.80960506
95EZH2_27294783_Chip-Seq_NPCs_Mouse0.80867321
96RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80770890
97EGR1_19374776_ChIP-ChIP_THP-1_Human0.80496788
98* CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.80406528
99ELK3_25401928_ChIP-Seq_HUVEC_Human0.80394713
100KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80216822
101FLI1_27457419_Chip-Seq_LIVER_Mouse0.80176165
102TAF2_19829295_ChIP-Seq_ESCs_Human0.79892710
103* RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.79614724
104THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.79381037
105EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.78279039
106GATA1_19941827_ChIP-Seq_MEL_Mouse0.77365643
107BCL6_27268052_Chip-Seq_Bcells_Human0.77182278
108* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76744020
109* FLI1_21867929_ChIP-Seq_CD8_Mouse0.76146222
110GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.74021852
111GATA6_21074721_ChIP-Seq_CACO-2_Human0.73908830
112GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.73260554
113* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.72385866
114IRF1_19129219_ChIP-ChIP_H3396_Human0.71528146
115GATA1_22383799_ChIP-Seq_G1ME_Mouse0.70671965
116FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70299211
117CRX_20693478_ChIP-Seq_RETINA_Mouse0.69432694
118KDM2B_26808549_Chip-Seq_JURKAT_Human0.68620664
119* PRDM14_20953172_ChIP-Seq_ESCs_Human0.67950514
120HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.67245133
121BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.66361472
122CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.66225465
123TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.65857037
124GABP_17652178_ChIP-ChIP_JURKAT_Human0.65680807
125BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.65018807
126SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.64881853
127RBPJ_21746931_ChIP-Seq_IB4_Human0.64559079
128STAT6_21828071_ChIP-Seq_BEAS2B_Human0.64242518
129CEBPB_22108803_ChIP-Seq_LS180_Human0.63802236
130NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.63411682
131* TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.63124023
132P300_27268052_Chip-Seq_Bcells_Human0.62859263
133CTCF_20526341_ChIP-Seq_ESCs_Human0.62360284
134FOXA1_27270436_Chip-Seq_PROSTATE_Human0.62176299
135FOXA1_25329375_ChIP-Seq_VCAP_Human0.62176299
136STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.61897222
137DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.61689021
138LXR_22292898_ChIP-Seq_THP-1_Human0.61259667
139AR_20517297_ChIP-Seq_VCAP_Human0.60580358
140SMRT_27268052_Chip-Seq_Bcells_Human0.60538384
141GATA1_22025678_ChIP-Seq_K562_Human0.60247969

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to6.20053028
2MP0003763_abnormal_thymus_physiology5.29839038
3MP0009785_altered_susceptibility_to3.66108601
4MP0003724_increased_susceptibility_to3.58834224
5MP0000685_abnormal_immune_system3.42558630
6MP0005000_abnormal_immune_tolerance3.37704329
7MP0001800_abnormal_humoral_immune3.30050296
8MP0001835_abnormal_antigen_presentation3.22956063
9MP0006082_CNS_inflammation3.18498514
10MP0002723_abnormal_immune_serum3.04104405
11MP0002420_abnormal_adaptive_immunity3.02281840
12MP0001819_abnormal_immune_cell2.98770081
13MP0005387_immune_system_phenotype2.94806977
14MP0001790_abnormal_immune_system2.94806977
15MP0009333_abnormal_splenocyte_physiolog2.82994049
16MP0002166_altered_tumor_susceptibility2.81889196
17MP0005025_abnormal_response_to2.76012019
18MP0002405_respiratory_system_inflammati2.74466501
19MP0002398_abnormal_bone_marrow2.71396645
20MP0002933_joint_inflammation2.63248887
21MP0002452_abnormal_antigen_presenting2.59980657
22MP0002006_tumorigenesis2.44147886
23MP0000716_abnormal_immune_system2.44064177
24MP0000703_abnormal_thymus_morphology2.43339195
25MP0004947_skin_inflammation2.33695931
26MP0002722_abnormal_immune_system2.26942503
27MP0000858_altered_metastatic_potential2.24422707
28MP0002148_abnormal_hypersensitivity_rea2.22327834
29MP0003436_decreased_susceptibility_to2.16424585
30MP0001873_stomach_inflammation2.11735685
31MP0010155_abnormal_intestine_physiology2.09285163
32MP0003866_abnormal_defecation2.07781926
33MP0000689_abnormal_spleen_morphology2.06176966
34MP0002419_abnormal_innate_immunity2.00339143
35MP0002429_abnormal_blood_cell1.93629247
36MP0001845_abnormal_inflammatory_respons1.79801393
37MP0004510_myositis1.76480824
38MP0003183_abnormal_peptide_metabolism1.72019387
39MP0005464_abnormal_platelet_physiology1.68969873
40MP0000569_abnormal_digit_pigmentation1.62092063
41MP0003448_altered_tumor_morphology1.61868639
42MP0003806_abnormal_nucleotide_metabolis1.59922691
43MP0001851_eye_inflammation1.59723458
44MP0003045_fibrosis1.57529153
45MP0002876_abnormal_thyroid_physiology1.54669184
46MP0002163_abnormal_gland_morphology1.52624366
47MP0010234_abnormal_vibrissa_follicle1.49236306
48MP0003300_gastrointestinal_ulcer1.48790363
49MP0004381_abnormal_hair_follicle1.45283632
50MP0002009_preneoplasia1.42531929
51MP0002877_abnormal_melanocyte_morpholog1.40680342
52MP0001853_heart_inflammation1.35546100
53MP0001533_abnormal_skeleton_physiology1.29575415
54MP0008469_abnormal_protein_level1.29094091
55MP0003303_peritoneal_inflammation1.27745062
56MP0004145_abnormal_muscle_electrophysio1.27709773
57MP0002998_abnormal_bone_remodeling1.26245894
58MP0002132_abnormal_respiratory_system1.23763211
59MP0000372_irregular_coat_pigmentation1.23392431
60MP0005075_abnormal_melanosome_morpholog1.18436764
61MP0002396_abnormal_hematopoietic_system1.17546191
62MP0002277_abnormal_respiratory_mucosa1.13103212
63MP0005310_abnormal_salivary_gland1.11752829
64MP0000343_altered_response_to1.07382989
65MP0010307_abnormal_tumor_latency0.97143959
66MP0001984_abnormal_olfaction0.96446174
67* MP0002019_abnormal_tumor_incidence0.92872318
68MP0000465_gastrointestinal_hemorrhage0.91048386
69MP0009763_increased_sensitivity_to0.90886441
70MP0003786_premature_aging0.81112806
71MP0000490_abnormal_crypts_of0.79784474
72MP0005670_abnormal_white_adipose0.78961339
73MP0009764_decreased_sensitivity_to0.77741961
74MP0005166_decreased_susceptibility_to0.74893774
75MP0006054_spinal_hemorrhage0.72928527
76MP0002136_abnormal_kidney_physiology0.71859895
77MP0005023_abnormal_wound_healing0.71750535
78MP0001502_abnormal_circadian_rhythm0.71553541
79MP0000249_abnormal_blood_vessel0.70629508
80MP0001666_abnormal_nutrient_absorption0.69144961
81MP0005379_endocrine/exocrine_gland_phen0.68933642
82MP0000015_abnormal_ear_pigmentation0.68826326
83MP0003453_abnormal_keratinocyte_physiol0.67294795
84MP0001188_hyperpigmentation0.63502135
85MP0001243_abnormal_dermal_layer0.62673899
86MP0005174_abnormal_tail_pigmentation0.62652495
87MP0000609_abnormal_liver_physiology0.60276723
88MP0010352_gastrointestinal_tract_polyps0.59444053
89MP0003172_abnormal_lysosome_physiology0.59295956
90MP0000477_abnormal_intestine_morphology0.55847452
91MP0000604_amyloidosis0.55683620
92MP0009765_abnormal_xenobiotic_induced0.53520222
93MP0003137_abnormal_impulse_conducting0.53111573
94MP0003795_abnormal_bone_structure0.51855469
95MP0002693_abnormal_pancreas_physiology0.51467275
96MP0000920_abnormal_myelination0.50749063
97MP0004808_abnormal_hematopoietic_stem0.47759409
98MP0001191_abnormal_skin_condition0.47667618
99MP0008872_abnormal_physiological_respon0.44189505
100MP0006036_abnormal_mitochondrial_physio0.44135870
101MP0001765_abnormal_ion_homeostasis0.43774740
102MP0001727_abnormal_embryo_implantation0.43270040
103MP0001663_abnormal_digestive_system0.42835884
104MP0005390_skeleton_phenotype0.42788777
105MP0001545_abnormal_hematopoietic_system0.42608708
106MP0005397_hematopoietic_system_phenotyp0.42608708
107MP0005165_increased_susceptibility_to0.42506692
108MP0001216_abnormal_epidermal_layer0.41863306
109MP0001919_abnormal_reproductive_system0.41707869
110MP0008873_increased_physiological_sensi0.41203148
111MP0002083_premature_death0.41095498
112MP0002102_abnormal_ear_morphology0.40973293
113MP0001501_abnormal_sleep_pattern0.40538908
114MP0002168_other_aberrant_phenotype0.40470383
115MP0000371_diluted_coat_color0.40436110
116MP0009643_abnormal_urine_homeostasis0.40055148
117MP0001986_abnormal_taste_sensitivity0.39961886
118MP0004883_abnormal_blood_vessel0.39830706
119MP0003567_abnormal_fetal_cardiomyocyte0.38902556
120MP0002138_abnormal_hepatobiliary_system0.38510568
121MP0008057_abnormal_DNA_replication0.38035863
122MP0002822_catalepsy0.37358131
123MP0005253_abnormal_eye_physiology0.36960051
124MP0003638_abnormal_response/metabolism_0.36400805
125MP0005319_abnormal_enzyme/_coenzyme0.36241516
126MP0002095_abnormal_skin_pigmentation0.34066691
127MP0000613_abnormal_salivary_gland0.34050831
128MP0003329_amyloid_beta_deposits0.33384588
129MP0001661_extended_life_span0.32516849
130MP0005584_abnormal_enzyme/coenzyme_acti0.32225647
131MP0005076_abnormal_cell_differentiation0.30830671
132MP0001881_abnormal_mammary_gland0.30753410

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)7.85857150
2Abnormality of T cell number (HP:0011839)7.49040429
3Myositis (HP:0100614)7.14135722
4Optic neuritis (HP:0100653)7.07639476
5Retrobulbar optic neuritis (HP:0100654)7.07639476
6Severe combined immunodeficiency (HP:0004430)6.90200985
7Orchitis (HP:0100796)6.67373604
8Combined immunodeficiency (HP:0005387)6.37248298
9Abnormality of T cells (HP:0002843)5.69261630
10IgM deficiency (HP:0002850)5.33299275
11Recurrent bronchitis (HP:0002837)5.17863036
12Keratoconjunctivitis sicca (HP:0001097)4.91936584
13Elevated erythrocyte sedimentation rate (HP:0003565)4.82190070
14IgG deficiency (HP:0004315)4.77718113
15Stomatitis (HP:0010280)4.66673259
16Thyroiditis (HP:0100646)4.56920157
17Hypoproteinemia (HP:0003075)4.54959998
18Autoimmune hemolytic anemia (HP:0001890)4.49134700
19Keratoconjunctivitis (HP:0001096)4.45795168
20Aplastic anemia (HP:0001915)4.37860738
21Pulmonary infiltrates (HP:0002113)4.33998168
22Eczematoid dermatitis (HP:0000976)4.04146010
23Increased IgM level (HP:0003496)3.96006683
24Abnormality of eosinophils (HP:0001879)3.79379558
25Abnormality of B cell number (HP:0010975)3.75912071
26B lymphocytopenia (HP:0010976)3.75912071
27Abnormality of T cell physiology (HP:0011840)3.75405647
28Hemoptysis (HP:0002105)3.72751810
29Nasal polyposis (HP:0100582)3.71736411
30Vasculitis (HP:0002633)3.66369308
31Joint swelling (HP:0001386)3.58333810
32IgA deficiency (HP:0002720)3.57488839
33Arterial thrombosis (HP:0004420)3.53773085
34Gangrene (HP:0100758)3.52656922
35Lymphopenia (HP:0001888)3.50739376
36Encephalitis (HP:0002383)3.43878021
37Chronic diarrhea (HP:0002028)3.41585373
38Recurrent fungal infections (HP:0002841)3.40909485
39Abnormality of macrophages (HP:0004311)3.33071405
40Abnormality of cells of the lymphoid lineage (HP:0012140)3.30547275
41Meningitis (HP:0001287)3.28844966
42Leukocytosis (HP:0001974)3.28417815
43Pulmonary embolism (HP:0002204)3.25048080
44Gastrointestinal infarctions (HP:0005244)3.17422841
45Recurrent sinusitis (HP:0011108)3.16901465
46Pustule (HP:0200039)3.04534875
47Recurrent cutaneous fungal infections (HP:0011370)3.03996249
48Chronic mucocutaneous candidiasis (HP:0002728)3.03996249
49Abnormality of the nasal mucosa (HP:0000433)3.03119375
50Anorexia (HP:0002039)3.02245925
51Recurrent abscess formation (HP:0002722)2.97834054
52Alveolar cell carcinoma (HP:0006519)2.91964141
53Abnormality of the prostate (HP:0008775)2.87746017
54Bronchitis (HP:0012387)2.83949209
55Panhypogammaglobulinemia (HP:0003139)2.82349912
56Hypoplasia of the thymus (HP:0000778)2.78742536
57Hemiplegia (HP:0002301)2.75003241
58Chronic obstructive pulmonary disease (HP:0006510)2.67376868
59Obstructive lung disease (HP:0006536)2.67376868
60Recurrent otitis media (HP:0000403)2.66515403
61Polyneuropathy (HP:0001271)2.62108688
62Chronic otitis media (HP:0000389)2.57764413
63Recurrent viral infections (HP:0004429)2.55053722
64Neoplasm of the tracheobronchial system (HP:0100552)2.51012892
65Recurrent skin infections (HP:0001581)2.47937319
66Acute hepatic failure (HP:0006554)2.47803452
67Mediastinal lymphadenopathy (HP:0100721)2.47680970
68Ureteral stenosis (HP:0000071)2.46765688
69Lymphoma (HP:0002665)2.42168685
70Decreased activity of mitochondrial respiratory chain (HP:0008972)2.40933005
71Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.40933005
72Glomerulopathy (HP:0100820)2.40314318
73Abnormality of the pericardium (HP:0001697)2.39823084
74Abnormality of the pleura (HP:0002103)2.39172654
75Keratitis (HP:0000491)2.34858628
76Hypergammaglobulinemia (HP:0010702)2.34667385
77Abnormality of male internal genitalia (HP:0000022)2.34494074
78Abnormal albumin level (HP:0012116)2.34005960
79Hypoalbuminemia (HP:0003073)2.34005960
80Gastrointestinal stroma tumor (HP:0100723)2.27454443
81Ureteral obstruction (HP:0006000)2.23176915
82Recurrent bacterial skin infections (HP:0005406)2.16180745
83Renal cortical cysts (HP:0000803)2.14582103
84J-shaped sella turcica (HP:0002680)2.13348773
85Arthralgia (HP:0002829)2.11363831
86Eosinophilia (HP:0001880)2.10760407
87Pulmonary fibrosis (HP:0002206)2.07092197
88Increased intramyocellular lipid droplets (HP:0012240)2.04729023
89Skin rash (HP:0000988)2.03950534
90Pancytopenia (HP:0001876)1.99757201
91Premature loss of primary teeth (HP:0006323)1.99127845
92Thrombophlebitis (HP:0004418)1.98391851
93Abnormality of the endocardium (HP:0004306)1.95222924
94Abnormal delayed hypersensitivity skin test (HP:0002963)1.93802571
95Agammaglobulinemia (HP:0004432)1.93277757
96Congenital stationary night blindness (HP:0007642)1.92627481
97Epistaxis (HP:0000421)1.91202919
98Abnormality of binocular vision (HP:0011514)1.90130944
99Diplopia (HP:0000651)1.90130944
100Abnormality of oral frenula (HP:0000190)1.89480595
101Cutaneous melanoma (HP:0012056)1.89125031
102Oral leukoplakia (HP:0002745)1.87528902
103Gingivitis (HP:0000230)1.85586323
104Amaurosis fugax (HP:0100576)1.85414259
105Chest pain (HP:0100749)1.83708013
106Restrictive lung disease (HP:0002091)1.82644829
107Carpal bone hypoplasia (HP:0001498)1.82396762
108Abnormality of the alveolar ridges (HP:0006477)1.81479087
109Petechiae (HP:0000967)1.81353185
110Premature graying of hair (HP:0002216)1.80984751
111Acrocyanosis (HP:0001063)1.80412633
112Thrombocytosis (HP:0001894)1.79345503
113Vertigo (HP:0002321)1.78429023
114Inflammation of the large intestine (HP:0002037)1.75911914
115Periodontitis (HP:0000704)1.74446015
116Pancreatitis (HP:0001733)1.73309787
117Trigonocephaly (HP:0000243)1.72952560
118Abnormality of the fingertips (HP:0001211)1.71476149
119Granulocytopenia (HP:0001913)1.71077270
120Gastrointestinal inflammation (HP:0004386)1.70608502
121Autoimmune thrombocytopenia (HP:0001973)1.68096346
122Aortic dissection (HP:0002647)1.63071788
123Acne (HP:0001061)1.62799491
124Increased density of long bones (HP:0006392)1.59187835
125Albinism (HP:0001022)1.57799355

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK8.67174368
2MAP4K15.75949194
3ZAP703.95389264
4ITK3.77300613
5JAK13.21180574
6MAP3K122.98527406
7TESK22.81303812
8IKBKE2.11796284
9KDR2.10606514
10JAK31.99651676
11FGFR41.97003454
12TEC1.93475795
13LCK1.91186617
14CSK1.85706295
15MAPKAPK31.82829880
16SYK1.76133923
17TYK21.74348914
18BCKDK1.71231954
19TBK11.68918612
20STK101.59687498
21MAP3K141.58843190
22GRK61.56694862
23EIF2AK11.55694032
24BLK1.46317592
25CAMKK21.45382536
26ADRBK21.43719244
27BTK1.42877623
28TAOK31.39462151
29HCK1.34543776
30PIK3CA1.24862627
31MST41.20529109
32FGFR31.18065283
33TESK11.09760853
34BMPR21.09318973
35FRK1.08049884
36PRKCQ1.07767558
37MYLK1.02696907
38IRAK41.01769071
39SCYL21.00704621
40LYN0.96857170
41IRAK30.95717969
42RIPK40.93019094
43IKBKB0.89717094
44TSSK60.87123797
45ERN10.87094587
46OBSCN0.83488973
47STK240.83232313
48MAP2K60.81185946
49NLK0.81125019
50WNK40.79787452
51STK390.78792902
52TNK20.78695244
53TYRO30.74163327
54KIT0.73550247
55SIK30.72670050
56LRRK20.71847966
57FYN0.69746931
58TGFBR20.66951779
59MUSK0.66376220
60MAP3K130.66343369
61FGFR10.66235941
62PRKCH0.64200273
63JAK20.62090069
64OXSR10.60238038
65FES0.59093263
66NUAK10.58033413
67IGF1R0.57763922
68PDGFRB0.57285269
69GRK10.56787074
70PIM10.54661323
71NEK90.54148092
72ILK0.54100638
73INSR0.54027428
74SIK20.53906214
75LIMK10.51156609
76CSF1R0.49542574
77CHUK0.48802159
78BCR0.48105290
79MATK0.47953765
80PTK20.46835832
81PINK10.46474189
82SRPK10.45543323
83MAP3K110.44743219
84CAMKK10.43577878
85NME10.42355870
86EPHA30.41100511
87EPHB10.41062327
88EIF2AK30.38989967
89TLK10.38907626
90NME20.35208384
91PRKCD0.34678889
92DAPK20.34124261
93CAMK2A0.33831784
94CLK10.33603821
95DMPK0.33580027
96DAPK10.32892983
97PRKCA0.32628185
98CDK40.32162593
99ACVR1B0.30323966
100MARK30.29894141
101GRK50.28687623
102NEK60.28600109
103RPS6KA40.28571479
104MELK0.27636232
105SIK10.25425183
106DAPK30.23773446
107EEF2K0.22351545
108PDK20.22311777
109PDK10.21983421
110SRC0.21474491
111CDK60.19858049
112PRKACA0.19140742
113VRK10.18781867
114GRK70.18310156
115ATR0.17358922
116IRAK10.16770225
117MAPK110.16466253
118STK110.16072935
119ABL10.15925358
120MAP3K70.15646902
121HIPK20.15227851
122CDK80.15144124
123BRSK20.14637309
124PRKD10.14366021
125EGFR0.14137231
126BUB10.13444228
127ZAK0.12940746
128PIK3CG0.12185438
129EIF2AK20.11904221
130ROCK20.11614800
131MAPK30.11138921
132CDK90.10740986
133PAK40.09814297
134PRKCB0.08281802
135MAPKAPK20.08145316

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053406.46176081
2Graft-versus-host disease_Homo sapiens_hsa053325.05369399
3Inflammatory bowel disease (IBD)_Homo sapiens_hsa053214.28822441
4Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046504.09910870
5T cell receptor signaling pathway_Homo sapiens_hsa046604.08879471
6Intestinal immune network for IgA production_Homo sapiens_hsa046723.68921844
7Antigen processing and presentation_Homo sapiens_hsa046123.43181051
8Allograft rejection_Homo sapiens_hsa053303.28495177
9Hematopoietic cell lineage_Homo sapiens_hsa046402.95913614
10Autoimmune thyroid disease_Homo sapiens_hsa053202.68851695
11Measles_Homo sapiens_hsa051622.67402447
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.18787418
13Viral myocarditis_Homo sapiens_hsa054161.88641628
14Jak-STAT signaling pathway_Homo sapiens_hsa046301.81902036
15Asthma_Homo sapiens_hsa053101.74300392
16Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.68428744
17* Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.67918358
18Osteoclast differentiation_Homo sapiens_hsa043801.63679358
19Leishmaniasis_Homo sapiens_hsa051401.55329536
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.44909546
21Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.38443008
22B cell receptor signaling pathway_Homo sapiens_hsa046621.20333292
23RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.15945919
24Herpes simplex infection_Homo sapiens_hsa051681.15475877
25Staphylococcus aureus infection_Homo sapiens_hsa051501.11425026
26Toxoplasmosis_Homo sapiens_hsa051451.06992042
27* Chemokine signaling pathway_Homo sapiens_hsa040621.06543416
28Leukocyte transendothelial migration_Homo sapiens_hsa046701.05492765
29Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.02342415
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.01047058
31Malaria_Homo sapiens_hsa051440.95662056
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95455419
33Type I diabetes mellitus_Homo sapiens_hsa049400.94337370
34TNF signaling pathway_Homo sapiens_hsa046680.93276721
35Apoptosis_Homo sapiens_hsa042100.92486265
36Shigellosis_Homo sapiens_hsa051310.82621930
37HTLV-I infection_Homo sapiens_hsa051660.82344146
38alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.81333145
39Influenza A_Homo sapiens_hsa051640.78131814
40VEGF signaling pathway_Homo sapiens_hsa043700.76193332
41Rheumatoid arthritis_Homo sapiens_hsa053230.75986208
42Ribosome_Homo sapiens_hsa030100.73336272
43Nitrogen metabolism_Homo sapiens_hsa009100.71724229
44Legionellosis_Homo sapiens_hsa051340.71170269
45Hepatitis B_Homo sapiens_hsa051610.70585422
46Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68088616
47Toll-like receptor signaling pathway_Homo sapiens_hsa046200.67611690
48Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65103505
49Oxidative phosphorylation_Homo sapiens_hsa001900.64044105
50Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59820961
51Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.58931185
52Phototransduction_Homo sapiens_hsa047440.58463334
53Epstein-Barr virus infection_Homo sapiens_hsa051690.56969192
54p53 signaling pathway_Homo sapiens_hsa041150.54683297
55Platelet activation_Homo sapiens_hsa046110.54434749
56Parkinsons disease_Homo sapiens_hsa050120.54327901
57Tuberculosis_Homo sapiens_hsa051520.54034658
58Linoleic acid metabolism_Homo sapiens_hsa005910.52433432
59Circadian rhythm_Homo sapiens_hsa047100.48613682
60Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48132695
61Salmonella infection_Homo sapiens_hsa051320.46694216
62Pancreatic cancer_Homo sapiens_hsa052120.45756597
63Endocytosis_Homo sapiens_hsa041440.45392319
64African trypanosomiasis_Homo sapiens_hsa051430.45125732
65Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40531102
66Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39769323
67Viral carcinogenesis_Homo sapiens_hsa052030.39590397
68Acute myeloid leukemia_Homo sapiens_hsa052210.38320980
69Hepatitis C_Homo sapiens_hsa051600.38192980
70Prolactin signaling pathway_Homo sapiens_hsa049170.37372954
71Protein export_Homo sapiens_hsa030600.35667071
72Regulation of autophagy_Homo sapiens_hsa041400.35289132
73Alzheimers disease_Homo sapiens_hsa050100.33731967
74Pertussis_Homo sapiens_hsa051330.33592403
75Colorectal cancer_Homo sapiens_hsa052100.32568360
76Peroxisome_Homo sapiens_hsa041460.32165133
77RNA degradation_Homo sapiens_hsa030180.31864201
78Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.31774630
79Systemic lupus erythematosus_Homo sapiens_hsa053220.31771463
80Proteasome_Homo sapiens_hsa030500.31256699
81Other glycan degradation_Homo sapiens_hsa005110.26521732
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.25743986
83FoxO signaling pathway_Homo sapiens_hsa040680.24303364
84Rap1 signaling pathway_Homo sapiens_hsa040150.24296784
85Sulfur metabolism_Homo sapiens_hsa009200.23106518
86Ether lipid metabolism_Homo sapiens_hsa005650.22699876
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.22690490
88Non-homologous end-joining_Homo sapiens_hsa034500.21933451
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.21057343
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20143823
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.19494003
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.19254142
93Mineral absorption_Homo sapiens_hsa049780.18083896
94Pentose phosphate pathway_Homo sapiens_hsa000300.16898539
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.15413607
96Lysosome_Homo sapiens_hsa041420.14617449
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.14242107
98Collecting duct acid secretion_Homo sapiens_hsa049660.13964914
99Mismatch repair_Homo sapiens_hsa034300.13275139
100Base excision repair_Homo sapiens_hsa034100.13171053
101DNA replication_Homo sapiens_hsa030300.12336614
102Cardiac muscle contraction_Homo sapiens_hsa042600.12328416
103Pyrimidine metabolism_Homo sapiens_hsa002400.10942598
104Chronic myeloid leukemia_Homo sapiens_hsa052200.10110971
105Homologous recombination_Homo sapiens_hsa034400.09150178
106Insulin resistance_Homo sapiens_hsa049310.08940578
107Drug metabolism - other enzymes_Homo sapiens_hsa009830.08700052
108Focal adhesion_Homo sapiens_hsa045100.07610492
109Spliceosome_Homo sapiens_hsa030400.06558014
110Selenocompound metabolism_Homo sapiens_hsa004500.06224720
111Vascular smooth muscle contraction_Homo sapiens_hsa042700.05660789
112RNA polymerase_Homo sapiens_hsa030200.05649511
113Purine metabolism_Homo sapiens_hsa002300.05376991
114MAPK signaling pathway_Homo sapiens_hsa040100.05308151
115Prion diseases_Homo sapiens_hsa050200.04770789
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.04358727
117Non-small cell lung cancer_Homo sapiens_hsa052230.04146209
118Notch signaling pathway_Homo sapiens_hsa043300.03983603
119Small cell lung cancer_Homo sapiens_hsa052220.03134998
120Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.01597698
121Huntingtons disease_Homo sapiens_hsa050160.01363082
122Caffeine metabolism_Homo sapiens_hsa002320.00890693
123Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.00099206
124Inositol phosphate metabolism_Homo sapiens_hsa00562-0.0502098
125Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410-0.0339279
126SNARE interactions in vesicular transport_Homo sapiens_hsa04130-0.0333100
127Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601-0.0191220
128ABC transporters_Homo sapiens_hsa02010-0.0142677

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