CYB561D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.39189470
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.39189470
3negative regulation of cell killing (GO:0031342)5.18137551
4negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.18137551
5positive regulation of gamma-delta T cell activation (GO:0046645)5.07989721
6antigen processing and presentation of endogenous antigen (GO:0019883)5.07903297
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.97299249
8positive regulation by organism of defense response of other organism involved in symbiotic interact4.97299249
9modulation by symbiont of host immune response (GO:0052553)4.97299249
10positive regulation by symbiont of host defense response (GO:0052509)4.97299249
11modulation by symbiont of host defense response (GO:0052031)4.97299249
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.97299249
13detection of other organism (GO:0098543)4.43416007
14regulation of B cell receptor signaling pathway (GO:0050855)4.38590355
15detection of bacterium (GO:0016045)4.35614809
16regulation of gamma-delta T cell differentiation (GO:0045586)4.29871589
17positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.28440352
18macrophage activation involved in immune response (GO:0002281)4.10857202
19response to peptidoglycan (GO:0032494)4.06374850
20negative regulation of lymphocyte mediated immunity (GO:0002707)4.02337371
21neutrophil activation involved in immune response (GO:0002283)3.96204603
22negative regulation of interleukin-12 production (GO:0032695)3.90675800
23regulation of gamma-delta T cell activation (GO:0046643)3.88818195
24B cell receptor signaling pathway (GO:0050853)3.85719895
25negative regulation of T cell mediated immunity (GO:0002710)3.80615679
26dicarboxylic acid biosynthetic process (GO:0043650)3.74705345
27detection of external biotic stimulus (GO:0098581)3.73034254
28cellular extravasation (GO:0045123)3.68269224
29negative regulation of leukocyte mediated immunity (GO:0002704)3.61015942
30positive thymic T cell selection (GO:0045059)3.50772497
31response to interleukin-15 (GO:0070672)3.49182591
32positive regulation of histone deacetylation (GO:0031065)3.48888635
33negative T cell selection (GO:0043383)3.48478859
34negative thymic T cell selection (GO:0045060)3.44832350
35respiratory burst (GO:0045730)3.42862063
36detection of molecule of bacterial origin (GO:0032490)3.42815773
37negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.40085474
38daunorubicin metabolic process (GO:0044597)3.39068498
39polyketide metabolic process (GO:0030638)3.39068498
40doxorubicin metabolic process (GO:0044598)3.39068498
41T cell selection (GO:0045058)3.38298704
42response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.37208263
43response to host immune response (GO:0052572)3.37208263
44positive T cell selection (GO:0043368)3.35606294
45positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.35475018
46regulation of interleukin-12 biosynthetic process (GO:0045075)3.34056402
47response to muramyl dipeptide (GO:0032495)3.33652599
48positive regulation of B cell differentiation (GO:0045579)3.30474510
49thymic T cell selection (GO:0045061)3.30124628
50neutrophil activation (GO:0042119)3.28642996
51sodium ion export (GO:0071436)3.26938112
52immunoglobulin mediated immune response (GO:0016064)3.24819210
53regulation of T cell mediated cytotoxicity (GO:0001914)3.21432860
54response to host (GO:0075136)3.20549545
55response to host defenses (GO:0052200)3.20549545
56response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.20549545
57JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.20475959
58detection of biotic stimulus (GO:0009595)3.19251770
59regulation of natural killer cell mediated immunity (GO:0002715)3.19098007
60regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.19098007
61regulation of B cell differentiation (GO:0045577)3.19088789
62negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.14040594
63regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.12490836
64cellular response to interleukin-15 (GO:0071350)3.11911789
65mature B cell differentiation (GO:0002335)3.09679574
66myeloid cell activation involved in immune response (GO:0002275)3.08871743
67positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.07281482
68granulocyte activation (GO:0036230)3.06490910
69leukocyte aggregation (GO:0070486)3.06035388
70regulation of tolerance induction (GO:0002643)3.05730519
71G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.05646177
72regulation of mast cell degranulation (GO:0043304)3.05339034
73glutamate secretion (GO:0014047)3.03234331
74negative regulation of type 2 immune response (GO:0002829)3.01676470
75positive regulation of T cell mediated cytotoxicity (GO:0001916)3.01255838
76regulation of dendritic cell antigen processing and presentation (GO:0002604)2.99418485
77germinal center formation (GO:0002467)2.97171527
78positive regulation of catecholamine secretion (GO:0033605)2.96257615
79regulation of leukocyte degranulation (GO:0043300)2.94544028
80negative regulation of innate immune response (GO:0045824)2.91646959
81antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.91137617
82macrophage activation (GO:0042116)2.90716642
83regulation of ARF protein signal transduction (GO:0032012)2.87560291
84regulation of isotype switching to IgG isotypes (GO:0048302)2.85609663
85NIK/NF-kappaB signaling (GO:0038061)2.84582117
86microglial cell activation (GO:0001774)2.83268444
87regulation of myeloid leukocyte mediated immunity (GO:0002886)2.82743539
88neutrophil mediated immunity (GO:0002446)2.82716456
89positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.81756181
90negative regulation of interleukin-6 production (GO:0032715)2.80060893
91production of molecular mediator involved in inflammatory response (GO:0002532)2.79787178
92regulation of alpha-beta T cell proliferation (GO:0046640)2.79744693
93negative regulation of erythrocyte differentiation (GO:0045647)2.78939463
94regulation of regulatory T cell differentiation (GO:0045589)2.77370879
95regulation of mast cell activation involved in immune response (GO:0033006)2.77238557
96regulation of T-helper 2 cell differentiation (GO:0045628)2.76846076
97regulation of short-term neuronal synaptic plasticity (GO:0048172)2.76552334
98regulation of regulated secretory pathway (GO:1903305)2.74958298
99synaptic vesicle maturation (GO:0016188)2.74872636
100regulation of leukocyte mediated cytotoxicity (GO:0001910)2.74075547
101positive regulation of mast cell activation (GO:0033005)2.73697993
102positive regulation of Rap GTPase activity (GO:0032854)2.73372822
103negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.72609847
104negative regulation of T-helper cell differentiation (GO:0045623)2.72609847
105positive regulation of CREB transcription factor activity (GO:0032793)2.71860553
106interferon-gamma secretion (GO:0072643)2.70873890
107adaptation of signaling pathway (GO:0023058)2.69235174
108negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.68456981
109interferon-gamma-mediated signaling pathway (GO:0060333)2.68207029
110T cell migration (GO:0072678)2.64000779
111antigen receptor-mediated signaling pathway (GO:0050851)2.62668908
112regulation of Rap GTPase activity (GO:0032317)2.59420790
113mature B cell differentiation involved in immune response (GO:0002313)2.57356641
114T cell costimulation (GO:0031295)2.49307680
115interferon-gamma production (GO:0032609)2.48937351
116heparin biosynthetic process (GO:0030210)2.48829043
117heparin metabolic process (GO:0030202)2.48829043
118lymphocyte costimulation (GO:0031294)2.48330206
119regulation of T cell receptor signaling pathway (GO:0050856)2.48273047
120T cell homeostasis (GO:0043029)2.47713428
121regulation of interferon-beta biosynthetic process (GO:0045357)2.46128096
122positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.45905365
123natural killer cell differentiation (GO:0001779)2.44811753
124regulation of ARF GTPase activity (GO:0032312)2.42913731
125regulation of T cell tolerance induction (GO:0002664)2.42710256
126cellular potassium ion homeostasis (GO:0030007)2.41243010
127ionotropic glutamate receptor signaling pathway (GO:0035235)2.40483893
128antigen processing and presentation via MHC class Ib (GO:0002475)2.38880809
129response to type I interferon (GO:0034340)2.38394205
130positive regulation of granulocyte differentiation (GO:0030854)2.36963712
131suckling behavior (GO:0001967)2.34968684
132T cell receptor signaling pathway (GO:0050852)2.34707012
133positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.33837208
134Peyers patch development (GO:0048541)2.32846899
135mucosal-associated lymphoid tissue development (GO:0048537)2.32846899
136positive regulation of protein deacetylation (GO:0090312)2.31007287
137activated T cell proliferation (GO:0050798)2.29871058
138type I interferon signaling pathway (GO:0060337)2.29133860
139cellular response to type I interferon (GO:0071357)2.29133860
140protein localization to endosome (GO:0036010)2.26334192
141locomotory exploration behavior (GO:0035641)2.26258916
142negative regulation of T cell receptor signaling pathway (GO:0050860)2.26013620
143myeloid dendritic cell differentiation (GO:0043011)2.23956770
144regulation of response to interferon-gamma (GO:0060330)2.21633704
145nerve growth factor signaling pathway (GO:0038180)2.21316277
146heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.20633796
147lymphocyte homeostasis (GO:0002260)2.19803867
148defense response to protozoan (GO:0042832)2.19557862
149serine transport (GO:0032329)2.19048368
150mast cell degranulation (GO:0043303)2.18576609
151mast cell activation involved in immune response (GO:0002279)2.18576609
152immune response-activating cell surface receptor signaling pathway (GO:0002429)2.18501111
153regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.16772024
154regulation of synaptic vesicle exocytosis (GO:2000300)2.16468061
155mast cell activation (GO:0045576)2.16378157
156regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.16244015
157membrane depolarization during action potential (GO:0086010)2.13622016
158response to protozoan (GO:0001562)2.12556963
159tolerance induction (GO:0002507)2.12253295
160positive regulation of natural killer cell differentiation (GO:0032825)2.11620959
161myeloid dendritic cell activation (GO:0001773)2.11363615
162cardiac left ventricle morphogenesis (GO:0003214)2.10379939

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.09949326
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.40838006
3RUNX_20019798_ChIP-Seq_JUKART_Human2.91180986
4MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.80719872
5MYC_22102868_ChIP-Seq_BL_Human2.77740545
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.58718219
7GATA1_22025678_ChIP-Seq_K562_Human2.58692496
8FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.51651190
9TCF7_22412390_ChIP-Seq_EML_Mouse2.44487957
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.42808376
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.40664144
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.34861399
13VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.34794354
14IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.30351417
15KDM2B_26808549_Chip-Seq_SUP-B15_Human2.28389196
16THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.27091383
17* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.23857405
18VDR_21846776_ChIP-Seq_THP-1_Human2.23384889
19E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.22253033
20SPI1_23127762_ChIP-Seq_K562_Human2.21115156
21MAF_26560356_Chip-Seq_TH1_Human2.20106092
22IRF8_27001747_Chip-Seq_BMDM_Mouse2.17238136
23STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.15420446
24IRF8_21731497_ChIP-ChIP_J774_Mouse2.12123471
25KDM2B_26808549_Chip-Seq_DND41_Human2.11220438
26NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.09118997
27EGR1_19374776_ChIP-ChIP_THP-1_Human2.05107002
28SCL_19346495_ChIP-Seq_HPC-7_Human2.03457333
29* KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.02137186
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.94341841
31MYB_26560356_Chip-Seq_TH2_Human1.92902222
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.88397416
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.83658014
34UTX_26944678_Chip-Seq_JUKART_Human1.83110498
35RARB_27405468_Chip-Seq_BRAIN_Mouse1.81694174
36VDR_24763502_ChIP-Seq_THP-1_Human1.77214441
37MYB_21317192_ChIP-Seq_ERMYB_Mouse1.74036164
38RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.71891271
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.70561300
40GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.67268025
41GATA1_19941827_ChIP-Seq_MEL_Mouse1.66936363
42PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.62680904
43MYB_26560356_Chip-Seq_TH1_Human1.61613659
44* LXR_22292898_ChIP-Seq_THP-1_Human1.57915030
45DROSHA_22980978_ChIP-Seq_HELA_Human1.56581576
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.56566153
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.49045687
48TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.48855608
49EZH2_22144423_ChIP-Seq_EOC_Human1.48375154
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46729253
51CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.46392634
52* KDM2B_26808549_Chip-Seq_JURKAT_Human1.40355173
53EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39744675
54* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.38413278
55PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.38271511
56NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.38239414
57GATA3_27048872_Chip-Seq_THYMUS_Human1.38109359
58TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37587042
59KDM2B_26808549_Chip-Seq_K562_Human1.33076978
60ELK3_25401928_ChIP-Seq_HUVEC_Human1.32928863
61STAT6_21828071_ChIP-Seq_BEAS2B_Human1.30991191
62BCL6_27268052_Chip-Seq_Bcells_Human1.29519879
63BCOR_27268052_Chip-Seq_Bcells_Human1.28772134
64CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28241384
65TP63_17297297_ChIP-ChIP_HaCaT_Human1.26868394
66PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23799935
67SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.23448156
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.22468584
69MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.21029729
70DNAJC2_21179169_ChIP-ChIP_NT2_Human1.20664007
71MAF_26560356_Chip-Seq_TH2_Human1.20266826
72LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.20134049
73PU.1_20513432_ChIP-Seq_Bcells_Mouse1.19183288
74NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.19121001
75PU_27001747_Chip-Seq_BMDM_Mouse1.18976446
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17806592
77LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17408886
78CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16668745
79P68_20966046_ChIP-Seq_HELA_Human1.15181470
80SPI1_23547873_ChIP-Seq_NB4_Human1.14450610
81SA1_27219007_Chip-Seq_ERYTHROID_Human1.14331565
82GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14232842
83GATA2_22383799_ChIP-Seq_G1ME_Mouse1.14224611
84GATA1_19941826_ChIP-Seq_K562_Human1.14053027
85VDR_24787735_ChIP-Seq_THP-1_Human1.13144835
86GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.12039415
87SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.11209527
88GATA2_19941826_ChIP-Seq_K562_Human1.09280321
89CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.09158577
90PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.08486708
91TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.08373321
92EGR1_19032775_ChIP-ChIP_M12_Human1.08327723
93SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.08125549
94* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.06362751
95* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06280681
96Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.05543099
97SMC4_20622854_ChIP-Seq_HELA_Human1.05390860
98ESR2_21235772_ChIP-Seq_MCF-7_Human1.05324576
99MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.01792158
100PPARA_22158963_ChIP-Seq_LIVER_Mouse1.00718990
101GATA3_26560356_Chip-Seq_TH2_Human1.00536469
102NR3C1_23031785_ChIP-Seq_PC12_Mouse1.00246610
103GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00159026
104SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.99909911
105ELF1_17652178_ChIP-ChIP_JURKAT_Human0.99643381
106ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.98404255
107SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.97980848
108SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.94740396
109SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.93202826
110CTCF_27219007_Chip-Seq_ERYTHROID_Human0.92008803
111P63_26484246_Chip-Seq_KERATINOCYTES_Human0.91362750
112TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90995306
113NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.90295420
114MTF2_20144788_ChIP-Seq_MESCs_Mouse0.88443154
115RARG_19884340_ChIP-ChIP_MEFs_Mouse0.87897150
116* CTCF_21964334_ChIP-Seq_BJAB-B_Human0.86939744
117PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.85885577
118NOTCH1_21737748_ChIP-Seq_TLL_Human0.85683976
119RUNX1_27514584_Chip-Seq_MCF-7_Human0.85337820
120GATA2_21666600_ChIP-Seq_HMVEC_Human0.84987375
121RACK7_27058665_Chip-Seq_MCF-7_Human0.84921507
122RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84550265
123* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.83860519
124ELF1_20517297_ChIP-Seq_JURKAT_Human0.83409129
125RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.82698120
126REST_18959480_ChIP-ChIP_MESCs_Mouse0.81115360
127FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.80202185
128KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.78829780

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.33430818
2MP0001835_abnormal_antigen_presentation2.90296137
3MP0004510_myositis2.58846433
4MP0001790_abnormal_immune_system2.57371188
5MP0005387_immune_system_phenotype2.57371188
6MP0003303_peritoneal_inflammation2.54857969
7MP0001800_abnormal_humoral_immune2.53025834
8MP0000685_abnormal_immune_system2.51011264
9MP0005671_abnormal_response_to2.22971130
10MP0003300_gastrointestinal_ulcer2.18755970
11MP0003763_abnormal_thymus_physiology2.10492841
12MP0001533_abnormal_skeleton_physiology2.07582339
13MP0005000_abnormal_immune_tolerance2.05162847
14MP0002452_abnormal_antigen_presenting2.02147821
15MP0002735_abnormal_chemical_nociception2.00258060
16MP0002723_abnormal_immune_serum2.00077727
17MP0008260_abnormal_autophagy1.96866481
18MP0005310_abnormal_salivary_gland1.95035482
19MP0002420_abnormal_adaptive_immunity1.93841791
20MP0002736_abnormal_nociception_after1.92175313
21MP0001819_abnormal_immune_cell1.91764527
22MP0001873_stomach_inflammation1.91104475
23MP0004381_abnormal_hair_follicle1.90487935
24MP0003436_decreased_susceptibility_to1.89565873
25MP0008961_abnormal_basal_metabolism1.88215312
26MP0009333_abnormal_splenocyte_physiolog1.84822113
27MP0005451_abnormal_body_composition1.84691443
28MP0001968_abnormal_touch/_nociception1.83344566
29MP0005670_abnormal_white_adipose1.81472236
30MP0005464_abnormal_platelet_physiology1.77078214
31MP0002398_abnormal_bone_marrow1.75769367
32MP0001501_abnormal_sleep_pattern1.74559753
33MP0004947_skin_inflammation1.72661525
34MP0002166_altered_tumor_susceptibility1.68813868
35MP0010234_abnormal_vibrissa_follicle1.66804108
36MP0005025_abnormal_response_to1.64223051
37MP0002138_abnormal_hepatobiliary_system1.60341384
38MP0000716_abnormal_immune_system1.56216712
39MP0009785_altered_susceptibility_to1.56088938
40MP0002419_abnormal_innate_immunity1.53108287
41MP0002822_catalepsy1.52821431
42MP0003866_abnormal_defecation1.50340861
43MP0003191_abnormal_cellular_cholesterol1.49560655
44MP0003635_abnormal_synaptic_transmissio1.48241805
45MP0004130_abnormal_muscle_cell1.40560212
46MP0002909_abnormal_adrenal_gland1.40331649
47MP0003183_abnormal_peptide_metabolism1.38832628
48MP0003075_altered_response_to1.37701738
49MP0003172_abnormal_lysosome_physiology1.34992567
50MP0000604_amyloidosis1.34331314
51MP0001845_abnormal_inflammatory_respons1.33896948
52MP0000013_abnormal_adipose_tissue1.33537423
53MP0002998_abnormal_bone_remodeling1.32307085
54MP0008874_decreased_physiological_sensi1.31690459
55MP0002148_abnormal_hypersensitivity_rea1.29439044
56MP0010155_abnormal_intestine_physiology1.29056090
57MP0000689_abnormal_spleen_morphology1.27960160
58MP0005075_abnormal_melanosome_morpholog1.27783358
59MP0008569_lethality_at_weaning1.27241154
60MP0002722_abnormal_immune_system1.27085837
61MP0002429_abnormal_blood_cell1.25277716
62MP0000858_altered_metastatic_potential1.25167370
63MP0005058_abnormal_lysosome_morphology1.24056973
64MP0004808_abnormal_hematopoietic_stem1.23784913
65MP0002405_respiratory_system_inflammati1.18009711
66MP0002132_abnormal_respiratory_system1.17224577
67MP0001851_eye_inflammation1.17210028
68MP0002064_seizures1.14203999
69MP0002006_tumorigenesis1.14094988
70MP0006082_CNS_inflammation1.13680607
71MP0002063_abnormal_learning/memory/cond1.11831736
72MP0002396_abnormal_hematopoietic_system1.11580265
73MP0000703_abnormal_thymus_morphology1.10963332
74MP0004858_abnormal_nervous_system1.09369855
75MP0008877_abnormal_DNA_methylation1.08797096
76MP0003828_pulmonary_edema1.08443651
77MP0009278_abnormal_bone_marrow1.08046924
78MP0002693_abnormal_pancreas_physiology1.07106246
79MP0002572_abnormal_emotion/affect_behav1.04673493
80MP0002254_reproductive_system_inflammat1.04426117
81MP0005174_abnormal_tail_pigmentation1.01908373
82MP0004883_abnormal_blood_vessel1.01712174
83MP0003045_fibrosis1.00925066
84MP0000003_abnormal_adipose_tissue1.00503891
85MP0001765_abnormal_ion_homeostasis0.99623279
86MP0003329_amyloid_beta_deposits0.99170343
87MP0002277_abnormal_respiratory_mucosa0.98525032
88MP0005166_decreased_susceptibility_to0.97755025
89MP0008469_abnormal_protein_level0.97614281
90MP0009745_abnormal_behavioral_response0.96571349
91MP0005390_skeleton_phenotype0.96428642
92MP0003705_abnormal_hypodermis_morpholog0.95992685
93MP0002877_abnormal_melanocyte_morpholog0.92975224
94MP0000015_abnormal_ear_pigmentation0.92930967
95MP0003656_abnormal_erythrocyte_physiolo0.92197638
96MP0002971_abnormal_brown_adipose0.89785890
97MP0001986_abnormal_taste_sensitivity0.89635067
98MP0009765_abnormal_xenobiotic_induced0.89501204
99MP0001663_abnormal_digestive_system0.86669058
100MP0000465_gastrointestinal_hemorrhage0.85503443
101MP0002272_abnormal_nervous_system0.83164283
102MP0002078_abnormal_glucose_homeostasis0.82887950
103MP0000516_abnormal_urinary_system0.80893071
104MP0005367_renal/urinary_system_phenotyp0.80893071
105MP0005360_urolithiasis0.80502514
106MP0000490_abnormal_crypts_of0.78831636
107MP0005164_abnormal_response_to0.78746621
108MP0003690_abnormal_glial_cell0.78629330
109MP0000609_abnormal_liver_physiology0.78507265
110MP0001853_heart_inflammation0.78174191
111MP0005375_adipose_tissue_phenotype0.78145599
112MP0005535_abnormal_body_temperature0.77843936
113MP0003724_increased_susceptibility_to0.77141188
114MP0001958_emphysema0.76914663
115MP0003091_abnormal_cell_migration0.75611857
116MP0005334_abnormal_fat_pad0.74078786
117MP0002796_impaired_skin_barrier0.73391875
118MP0002933_joint_inflammation0.73194047
119MP0003448_altered_tumor_morphology0.73032681
120MP0003633_abnormal_nervous_system0.72658208
121MP0004185_abnormal_adipocyte_glucose0.71852139
122MP0003879_abnormal_hair_cell0.71693730
123MP0001348_abnormal_lacrimal_gland0.70843014
124MP0005076_abnormal_cell_differentiation0.70679555
125MP0003453_abnormal_keratinocyte_physiol0.70165183
126MP0009840_abnormal_foam_cell0.70065997
127MP0003795_abnormal_bone_structure0.69803685
128MP0009764_decreased_sensitivity_to0.69687269
129MP0009780_abnormal_chondrocyte_physiolo0.69358062
130MP0009763_increased_sensitivity_to0.63541587
131MP0001849_ear_inflammation0.62045693
132MP0004264_abnormal_extraembryonic_tissu0.60647511
133MP0000343_altered_response_to0.58645591
134MP0005397_hematopoietic_system_phenotyp0.57157950
135MP0001545_abnormal_hematopoietic_system0.57157950
136MP0000249_abnormal_blood_vessel0.55662084
137MP0002009_preneoplasia0.55072197
138MP0002332_abnormal_exercise_endurance0.52409983
139MP0005319_abnormal_enzyme/_coenzyme0.52396149

Predicted human phenotypes

RankGene SetZ-score
1Myositis (HP:0100614)5.14835966
2Orchitis (HP:0100796)4.88621916
3Retrobulbar optic neuritis (HP:0100654)4.51871099
4Optic neuritis (HP:0100653)4.51871099
5Gastrointestinal infarctions (HP:0005244)4.12017100
6Chronic otitis media (HP:0000389)3.68669186
7Chronic obstructive pulmonary disease (HP:0006510)3.52043321
8Obstructive lung disease (HP:0006536)3.52043321
9Encephalitis (HP:0002383)3.42356450
10Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.41438487
11Recurrent viral infections (HP:0004429)3.40645634
12Eczematoid dermatitis (HP:0000976)3.36176987
13Recurrent fungal infections (HP:0002841)3.34364957
14Gastrointestinal inflammation (HP:0004386)3.29772164
15Inflammation of the large intestine (HP:0002037)3.28724859
16Keratoconjunctivitis sicca (HP:0001097)3.25553918
17Agammaglobulinemia (HP:0004432)3.24665136
18Colitis (HP:0002583)3.17685487
19Frequent falls (HP:0002359)3.05918859
20Pulmonary infiltrates (HP:0002113)3.03814117
21Keratoconjunctivitis (HP:0001096)3.00637167
22Urticaria (HP:0001025)3.00335045
23Abnormal delayed hypersensitivity skin test (HP:0002963)2.99431108
24Calf muscle hypertrophy (HP:0008981)2.98610974
25Verrucae (HP:0200043)2.93760887
26Papilloma (HP:0012740)2.93760887
27Hemoptysis (HP:0002105)2.93239110
28Cellulitis (HP:0100658)2.90935594
29T lymphocytopenia (HP:0005403)2.89669911
30Limb-girdle muscle atrophy (HP:0003797)2.87169667
31Recurrent abscess formation (HP:0002722)2.85994420
32Thyroiditis (HP:0100646)2.83642807
33Recurrent bacterial skin infections (HP:0005406)2.83513195
34Nasal polyposis (HP:0100582)2.78336742
35Recurrent bronchitis (HP:0002837)2.77619961
36Abnormality of T cell number (HP:0011839)2.76515616
37Panhypogammaglobulinemia (HP:0003139)2.76386669
38Increased IgM level (HP:0003496)2.73821389
39Abnormality of glycosphingolipid metabolism (HP:0004343)2.71487716
40Abnormality of glycolipid metabolism (HP:0010969)2.71487716
41Abnormality of liposaccharide metabolism (HP:0010968)2.71487716
42Muscle hypertrophy of the lower extremities (HP:0008968)2.69382627
43Recurrent cutaneous fungal infections (HP:0011370)2.59769488
44Chronic mucocutaneous candidiasis (HP:0002728)2.59769488
45Dysostosis multiplex (HP:0000943)2.58238104
46IgM deficiency (HP:0002850)2.58035652
47Episodic fever (HP:0001954)2.57682629
48Increased IgE level (HP:0003212)2.55770727
49Hypochromic anemia (HP:0001931)2.54318441
50Prolonged bleeding time (HP:0003010)2.53117716
51Peritonitis (HP:0002586)2.50174054
52Leukocytosis (HP:0001974)2.49872400
53Chronic sinusitis (HP:0011109)2.48982564
54Arterial thrombosis (HP:0004420)2.48203977
55Mediastinal lymphadenopathy (HP:0100721)2.47142440
56Abnormality of the nasal mucosa (HP:0000433)2.42736674
57Papilledema (HP:0001085)2.41677538
58Impaired social interactions (HP:0000735)2.41422154
59Abnormal social behavior (HP:0012433)2.41422154
60Autoimmune thrombocytopenia (HP:0001973)2.40862198
61Meningitis (HP:0001287)2.36268076
62Hypergammaglobulinemia (HP:0010702)2.32830495
63Urinary glycosaminoglycan excretion (HP:0003541)2.32685005
64Mucopolysacchariduria (HP:0008155)2.32685005
65Anorexia (HP:0002039)2.32313034
66Granulocytopenia (HP:0001913)2.31854634
67Visual hallucinations (HP:0002367)2.31587398
68Cheilitis (HP:0100825)2.31524678
69Restrictive lung disease (HP:0002091)2.31396400
70Supranuclear gaze palsy (HP:0000605)2.30172516
71Severe combined immunodeficiency (HP:0004430)2.29666455
72Focal motor seizures (HP:0011153)2.29351991
73Recurrent skin infections (HP:0001581)2.25535702
74Pelvic girdle muscle weakness (HP:0003749)2.25406770
75Vacuolated lymphocytes (HP:0001922)2.24879349
76Poor eye contact (HP:0000817)2.24604400
77Achilles tendon contracture (HP:0001771)2.23807578
78Slow saccadic eye movements (HP:0000514)2.22728709
79Febrile seizures (HP:0002373)2.22593007
80Abnormality of T cells (HP:0002843)2.22506218
81Pulmonary embolism (HP:0002204)2.22080819
82Increased neuronal autofluorescent lipopigment (HP:0002074)2.20476889
83Hypoventilation (HP:0002791)2.18572309
84Recurrent gram-negative bacterial infections (HP:0005420)2.18530856
85Centrally nucleated skeletal muscle fibers (HP:0003687)2.18366832
86Gangrene (HP:0100758)2.16124062
87Focal seizures (HP:0007359)2.15967329
88Abnormality of polysaccharide metabolism (HP:0011012)2.14873735
89Abnormality of glycosaminoglycan metabolism (HP:0004371)2.14873735
90Abnormality of mucopolysaccharide metabolism (HP:0011020)2.14873735
91Hypochromic microcytic anemia (HP:0004840)2.14775226
92Impaired platelet aggregation (HP:0003540)2.14092599
93Abnormal platelet function (HP:0011869)2.14092599
94Acute hepatic failure (HP:0006554)2.13517836
95Myoglobinuria (HP:0002913)2.13406466
96Elevated erythrocyte sedimentation rate (HP:0003565)2.12576205
97Abnormality of the endocardium (HP:0004306)2.12318775
98Deep palmar crease (HP:0006191)2.12232203
99Abnormality of the Achilles tendon (HP:0005109)2.11553050
100Abnormality of the peritoneum (HP:0002585)2.10469439
101Lymphopenia (HP:0001888)2.10410911
102Amyloidosis (HP:0011034)2.09680288
103Stomatitis (HP:0010280)2.09440912
104Fatigue (HP:0012378)2.09392165
105Vasculitis (HP:0002633)2.06488103
106Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.05557482
107Abnormality of the pleura (HP:0002103)2.05443083
108Increased cerebral lipofuscin (HP:0011813)2.04619243
109Combined immunodeficiency (HP:0005387)2.03654512
110Interstitial pulmonary disease (HP:0006530)2.03428845
111Gingivitis (HP:0000230)2.03069403
112Global brain atrophy (HP:0002283)2.02565728
113Abnormality of macrophages (HP:0004311)2.01576681
114Loss of speech (HP:0002371)2.01109184
115Chronic diarrhea (HP:0002028)2.01100181
116Increased serum ferritin (HP:0003281)2.00577830
117Acne (HP:0001061)2.00229424
118Abnormality of cells of the lymphoid lineage (HP:0012140)1.99455414
119Skin ulcer (HP:0200042)1.99438783
120Epistaxis (HP:0000421)1.99131603
121Petechiae (HP:0000967)1.94528487
122Gingival bleeding (HP:0000225)1.93894804
123Chest pain (HP:0100749)1.93871070
124Pustule (HP:0200039)1.92214766
125Abnormality of the musculature of the pelvis (HP:0001469)1.90341845
126Abnormality of the hip-girdle musculature (HP:0001445)1.90341845
127Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.90297578
128Cerebellar dysplasia (HP:0007033)1.87583195
129Sepsis (HP:0100806)1.86391791
130Spontaneous hematomas (HP:0007420)1.86126773
131Emphysema (HP:0002097)1.85635149
132Keratitis (HP:0000491)1.83569574
133Abnormality of iron homeostasis (HP:0011031)1.83089956
134Joint swelling (HP:0001386)1.82871905
135Hypoplasia of the thymus (HP:0000778)1.82371962
136Abnormality of B cell number (HP:0010975)1.82286383
137B lymphocytopenia (HP:0010976)1.82286383
138Gastrointestinal stroma tumor (HP:0100723)1.82113165
139Abnormality of T cell physiology (HP:0011840)1.79913664
140Postural instability (HP:0002172)1.77315736
141Macroorchidism (HP:0000053)1.76931185
142Epileptic encephalopathy (HP:0200134)1.73263823
143Neuronal loss in central nervous system (HP:0002529)1.72413396
144Shoulder girdle muscle weakness (HP:0003547)1.71397563
145Osteomyelitis (HP:0002754)1.71073876

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.53574082
2MAP3K133.21790055
3RIPK43.19562849
4PRPF4B2.95638734
5SIK22.71663783
6MAP3K92.65665688
7IRAK42.46051021
8GRK62.31410685
9ERN12.08590905
10TYK21.94555783
11JAK11.80962818
12DAPK21.76836188
13FES1.71913559
14SYK1.66460949
15KSR21.63520042
16CAMKK21.63286678
17NTRK31.63044952
18ITK1.54667411
19MAP3K31.51034904
20PKN21.47598749
21HCK1.47430424
22BTK1.45811152
23TRIB31.45533951
24MAP3K101.45390626
25EPHA41.45201650
26ZAP701.42070459
27FGFR41.40634977
28EEF2K1.34880840
29MAP3K71.34800107
30ARAF1.31483329
31JAK31.28104399
32PRKCH1.26357184
33MAP3K11.23831495
34SIK31.22561708
35CAMKK11.20295077
36SMG11.18059201
37TXK1.17966461
38TBK11.17492136
39FGFR31.16432122
40TEC1.15678699
41TAOK31.15421999
42CAMK1D1.12910718
43JAK21.11911523
44PTK61.10195514
45RAF11.09768138
46HIPK21.09473596
47TNK21.06704325
48BLK1.06417826
49MAP3K21.05556491
50IRAK31.03606929
51FGR1.02555683
52CAMK1G1.00465714
53STK100.97678883
54MAP3K140.96945748
55CDC42BPA0.92368636
56TAOK10.91493228
57LYN0.90886339
58MAP3K40.90521237
59KIT0.89197295
60LCK0.87275361
61CSK0.86436867
62CSF1R0.85410587
63IKBKE0.84879352
64YES10.84532147
65TGFBR20.84447577
66IKBKB0.84340018
67PDK10.82035888
68PRKCQ0.80766098
69CDK90.80653205
70DAPK10.80255696
71RPS6KA20.78087973
72MAP2K10.77989062
73STK380.77897625
74TESK20.77606622
75RET0.74893186
76TAOK20.73840974
77SIK10.73015641
78MARK30.69972042
79MAP3K120.69714228
80DYRK1B0.68930087
81EPHB10.67344572
82MAPK120.66797353
83SGK30.66686729
84MAPK70.65800923
85IRAK20.65388475
86CAMK10.65387222
87MARK20.65338678
88PRKD20.65273961
89ALK0.63767185
90MAP3K110.63141337
91MAP2K60.61831903
92LRRK20.60792219
93FLT30.59595257
94MAP2K30.57186634
95DMPK0.57134435
96MATK0.56997212
97PDPK10.56193955
98CDK50.56156425
99RIPK10.56101742
100PRKD30.54089580
101FYN0.53668213
102MAP2K20.51414068
103ABL10.50625275
104CDK120.50467242
105NTRK20.50204766
106STK110.49487009
107TTN0.48719218
108MAP2K40.47985547
109MAPK40.47951936
110IRAK10.47561933
111GRK70.47239643
112PASK0.46578982
113KSR10.44421007
114RPS6KC10.44256391
115RPS6KL10.44256391
116MAPK110.41899770
117SGK20.41769136
118BMPR20.41295809
119ICK0.39855367
120CLK10.39728680
121CHUK0.38658535
122MINK10.38606115
123RPS6KA60.37279681
124MOS0.36615186
125MAP3K50.36120988
126PTK2B0.35593743
127MAPKAPK20.35247658

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.49256392
2Primary immunodeficiency_Homo sapiens_hsa053402.33476188
3Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.31456083
4Graft-versus-host disease_Homo sapiens_hsa053322.12890924
5Allograft rejection_Homo sapiens_hsa053302.06318484
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.02141451
7Long-term potentiation_Homo sapiens_hsa047201.95531553
8Autoimmune thyroid disease_Homo sapiens_hsa053201.95507507
9T cell receptor signaling pathway_Homo sapiens_hsa046601.80761929
10Osteoclast differentiation_Homo sapiens_hsa043801.75393999
11Type I diabetes mellitus_Homo sapiens_hsa049401.64851843
12Other glycan degradation_Homo sapiens_hsa005111.59932475
13Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.55317979
14NOD-like receptor signaling pathway_Homo sapiens_hsa046211.49151163
15Circadian entrainment_Homo sapiens_hsa047131.47307874
16Leishmaniasis_Homo sapiens_hsa051401.46758298
17Olfactory transduction_Homo sapiens_hsa047401.45459819
18Glutamatergic synapse_Homo sapiens_hsa047241.44095402
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.43939200
20Salivary secretion_Homo sapiens_hsa049701.40346744
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.33463845
22Amphetamine addiction_Homo sapiens_hsa050311.32029173
23Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.31721023
24Insulin secretion_Homo sapiens_hsa049111.29772843
25Malaria_Homo sapiens_hsa051441.29616424
26Viral myocarditis_Homo sapiens_hsa054161.29309451
27Type II diabetes mellitus_Homo sapiens_hsa049301.28137481
28Hepatitis C_Homo sapiens_hsa051601.25846477
29Phosphatidylinositol signaling system_Homo sapiens_hsa040701.25731560
30Synaptic vesicle cycle_Homo sapiens_hsa047211.24946601
31Carbohydrate digestion and absorption_Homo sapiens_hsa049731.23657061
32Renin secretion_Homo sapiens_hsa049241.20770043
33Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.20521149
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.18128571
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.17095203
36Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.15387229
37Lysosome_Homo sapiens_hsa041421.14917209
38Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.14794053
39Chemokine signaling pathway_Homo sapiens_hsa040621.13442936
40Cocaine addiction_Homo sapiens_hsa050301.13288360
41Phagosome_Homo sapiens_hsa041451.12748039
42Herpes simplex infection_Homo sapiens_hsa051681.11964731
43Intestinal immune network for IgA production_Homo sapiens_hsa046721.11937237
44Arginine biosynthesis_Homo sapiens_hsa002201.11911110
45Neurotrophin signaling pathway_Homo sapiens_hsa047221.11252646
46Gastric acid secretion_Homo sapiens_hsa049711.10577017
47Dopaminergic synapse_Homo sapiens_hsa047281.10294321
48Oxytocin signaling pathway_Homo sapiens_hsa049211.06876685
49VEGF signaling pathway_Homo sapiens_hsa043701.06473984
50Nicotine addiction_Homo sapiens_hsa050331.05705319
51Long-term depression_Homo sapiens_hsa047301.05118142
52Morphine addiction_Homo sapiens_hsa050321.05064293
53Toll-like receptor signaling pathway_Homo sapiens_hsa046201.04972568
54Cholinergic synapse_Homo sapiens_hsa047251.03190317
55NF-kappa B signaling pathway_Homo sapiens_hsa040641.02834672
56Acute myeloid leukemia_Homo sapiens_hsa052211.01930159
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.01777236
58Platelet activation_Homo sapiens_hsa046111.01446563
59Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.00091717
60Non-small cell lung cancer_Homo sapiens_hsa052230.99520985
61Renal cell carcinoma_Homo sapiens_hsa052110.97430948
62GABAergic synapse_Homo sapiens_hsa047270.95273448
63Insulin resistance_Homo sapiens_hsa049310.94811437
64Tuberculosis_Homo sapiens_hsa051520.93458763
65Asthma_Homo sapiens_hsa053100.93281932
66Hematopoietic cell lineage_Homo sapiens_hsa046400.92549385
67Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.92529448
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.92305109
69Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.91285704
70Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.90764436
71Endometrial cancer_Homo sapiens_hsa052130.90410982
72Prolactin signaling pathway_Homo sapiens_hsa049170.90074483
73Legionellosis_Homo sapiens_hsa051340.89583306
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.89348510
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87794725
76Shigellosis_Homo sapiens_hsa051310.86880163
77Rheumatoid arthritis_Homo sapiens_hsa053230.85954415
78Endocytosis_Homo sapiens_hsa041440.85126992
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84332271
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.83534544
81SNARE interactions in vesicular transport_Homo sapiens_hsa041300.83081318
82Chronic myeloid leukemia_Homo sapiens_hsa052200.83063739
83GnRH signaling pathway_Homo sapiens_hsa049120.83017102
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.81433482
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81384226
86Toxoplasmosis_Homo sapiens_hsa051450.80672429
87Measles_Homo sapiens_hsa051620.80371543
88Calcium signaling pathway_Homo sapiens_hsa040200.79747979
89mTOR signaling pathway_Homo sapiens_hsa041500.78043569
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.77579127
91Choline metabolism in cancer_Homo sapiens_hsa052310.77571275
92Glioma_Homo sapiens_hsa052140.77064822
93Salmonella infection_Homo sapiens_hsa051320.76983423
94Leukocyte transendothelial migration_Homo sapiens_hsa046700.76445095
95Notch signaling pathway_Homo sapiens_hsa043300.74670280
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74261121
97Pancreatic secretion_Homo sapiens_hsa049720.74215638
98cAMP signaling pathway_Homo sapiens_hsa040240.71942493
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69933965
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.69448025
101Pertussis_Homo sapiens_hsa051330.69112424
102Hepatitis B_Homo sapiens_hsa051610.68726195
103MAPK signaling pathway_Homo sapiens_hsa040100.66827524
104Estrogen signaling pathway_Homo sapiens_hsa049150.66399182
105Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.65858512
106RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.65661285
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65591137
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64966251
109Vibrio cholerae infection_Homo sapiens_hsa051100.64872682
110FoxO signaling pathway_Homo sapiens_hsa040680.64176737
111TNF signaling pathway_Homo sapiens_hsa046680.61169664
112Staphylococcus aureus infection_Homo sapiens_hsa051500.61038779
113ErbB signaling pathway_Homo sapiens_hsa040120.60796310
114Insulin signaling pathway_Homo sapiens_hsa049100.59734562
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.59302460
116Antigen processing and presentation_Homo sapiens_hsa046120.58993165
117ABC transporters_Homo sapiens_hsa020100.58776751
118Caffeine metabolism_Homo sapiens_hsa002320.58444796
119Inositol phosphate metabolism_Homo sapiens_hsa005620.58400262
120Epstein-Barr virus infection_Homo sapiens_hsa051690.58268096
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57262905
122Influenza A_Homo sapiens_hsa051640.56884629
123Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55926307
124Apoptosis_Homo sapiens_hsa042100.55887426
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.55840765
126Pancreatic cancer_Homo sapiens_hsa052120.55828175
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.55126820
128AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54808287
129Dorso-ventral axis formation_Homo sapiens_hsa043200.54302148
130African trypanosomiasis_Homo sapiens_hsa051430.53755115
131Glucagon signaling pathway_Homo sapiens_hsa049220.52978113
132Taste transduction_Homo sapiens_hsa047420.52575376
133HTLV-I infection_Homo sapiens_hsa051660.52328640
134Glycerophospholipid metabolism_Homo sapiens_hsa005640.48833506
135Viral carcinogenesis_Homo sapiens_hsa052030.47037518
136Amoebiasis_Homo sapiens_hsa051460.45659834
137Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.45188168
138Colorectal cancer_Homo sapiens_hsa052100.44490888
139Bladder cancer_Homo sapiens_hsa052190.43878360
140Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43598443
141Prostate cancer_Homo sapiens_hsa052150.43328454

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