Rank | Gene Set | Z-score |
---|---|---|
1 | axon ensheathment in central nervous system (GO:0032291) | 5.86085706 |
2 | central nervous system myelination (GO:0022010) | 5.86085706 |
3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.48535867 |
4 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.28305954 |
5 | chaperone-mediated protein transport (GO:0072321) | 5.19427357 |
6 | ATP synthesis coupled proton transport (GO:0015986) | 5.13554205 |
7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.13554205 |
8 | fatty acid elongation (GO:0030497) | 4.97706229 |
9 | proteasome assembly (GO:0043248) | 4.67523336 |
10 | respiratory electron transport chain (GO:0022904) | 4.65513462 |
11 | electron transport chain (GO:0022900) | 4.57248799 |
12 | protein neddylation (GO:0045116) | 4.37054311 |
13 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.33959143 |
14 | signal peptide processing (GO:0006465) | 4.04535369 |
15 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.94891542 |
16 | protein complex biogenesis (GO:0070271) | 3.91099636 |
17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.89496834 |
18 | NADH dehydrogenase complex assembly (GO:0010257) | 3.89496834 |
19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.89496834 |
20 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.88215408 |
21 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.86382682 |
22 | termination of RNA polymerase III transcription (GO:0006386) | 3.86382682 |
23 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.83624091 |
24 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.79248993 |
25 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.74748007 |
26 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.73842817 |
27 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.71611073 |
28 | cholesterol biosynthetic process (GO:0006695) | 3.65974173 |
29 | negative regulation of cell killing (GO:0031342) | 3.60519803 |
30 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.60519803 |
31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.58507273 |
32 | negative regulation of ligase activity (GO:0051352) | 3.58507273 |
33 | cotranslational protein targeting to membrane (GO:0006613) | 3.56387626 |
34 | protein targeting to mitochondrion (GO:0006626) | 3.56243882 |
35 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.55219124 |
36 | mannosylation (GO:0097502) | 3.53619917 |
37 | immunoglobulin mediated immune response (GO:0016064) | 3.50218840 |
38 | ribosomal small subunit biogenesis (GO:0042274) | 3.49346318 |
39 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.48336929 |
40 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.47422742 |
41 | L-methionine salvage (GO:0071267) | 3.47151691 |
42 | L-methionine biosynthetic process (GO:0071265) | 3.47151691 |
43 | amino acid salvage (GO:0043102) | 3.47151691 |
44 | protein targeting to ER (GO:0045047) | 3.44740032 |
45 | protein localization to endoplasmic reticulum (GO:0070972) | 3.44441689 |
46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.43183271 |
47 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.42600676 |
48 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.42546253 |
49 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.40765988 |
50 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.40765988 |
51 | establishment of protein localization to mitochondrion (GO:0072655) | 3.40425046 |
52 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.36024839 |
53 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.36024839 |
54 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.36024839 |
55 | cytidine metabolic process (GO:0046087) | 3.34409018 |
56 | cytidine catabolic process (GO:0006216) | 3.34409018 |
57 | cytidine deamination (GO:0009972) | 3.34409018 |
58 | GPI anchor biosynthetic process (GO:0006506) | 3.30642519 |
59 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.30506959 |
60 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.29459715 |
61 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.29063483 |
62 | metallo-sulfur cluster assembly (GO:0031163) | 3.28945733 |
63 | iron-sulfur cluster assembly (GO:0016226) | 3.28945733 |
64 | sterol biosynthetic process (GO:0016126) | 3.28256649 |
65 | viral transcription (GO:0019083) | 3.27864203 |
66 | isoprenoid biosynthetic process (GO:0008299) | 3.26545224 |
67 | GTP biosynthetic process (GO:0006183) | 3.26337826 |
68 | cellular response to interleukin-15 (GO:0071350) | 3.24304314 |
69 | 7-methylguanosine mRNA capping (GO:0006370) | 3.23808413 |
70 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.22384368 |
71 | establishment of viral latency (GO:0019043) | 3.21993005 |
72 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.21232080 |
73 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.21232080 |
74 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.20122941 |
75 | 7-methylguanosine RNA capping (GO:0009452) | 3.18505136 |
76 | RNA capping (GO:0036260) | 3.18505136 |
77 | response to interferon-beta (GO:0035456) | 3.17561443 |
78 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.14611360 |
79 | cullin deneddylation (GO:0010388) | 3.13922335 |
80 | respiratory chain complex IV assembly (GO:0008535) | 3.13345019 |
81 | DNA deamination (GO:0045006) | 3.12924753 |
82 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.11354768 |
83 | regulation of cellular amine metabolic process (GO:0033238) | 3.09635614 |
84 | protein localization to mitochondrion (GO:0070585) | 3.09287982 |
85 | translational termination (GO:0006415) | 3.07937415 |
86 | leukocyte aggregation (GO:0070486) | 3.05323719 |
87 | protein deneddylation (GO:0000338) | 3.04552143 |
88 | quinone biosynthetic process (GO:1901663) | 3.02034850 |
89 | ubiquinone biosynthetic process (GO:0006744) | 3.02034850 |
90 | neutrophil activation involved in immune response (GO:0002283) | 3.01704603 |
91 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.00442583 |
92 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.97910685 |
93 | GPI anchor metabolic process (GO:0006505) | 2.96912136 |
94 | amyloid precursor protein metabolic process (GO:0042982) | 2.96904894 |
95 | NIK/NF-kappaB signaling (GO:0038061) | 2.96789863 |
96 | positive thymic T cell selection (GO:0045059) | 2.94767385 |
97 | ribosomal small subunit assembly (GO:0000028) | 2.93304334 |
98 | CTP metabolic process (GO:0046036) | 2.92782228 |
99 | CTP biosynthetic process (GO:0006241) | 2.92782228 |
100 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.92228287 |
101 | ubiquinone metabolic process (GO:0006743) | 2.91924566 |
102 | establishment of integrated proviral latency (GO:0075713) | 2.91818433 |
103 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.91238447 |
104 | B cell mediated immunity (GO:0019724) | 2.90311342 |
105 | substantia nigra development (GO:0021762) | 2.89886085 |
106 | regulation of mitochondrial translation (GO:0070129) | 2.88664389 |
107 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.88419001 |
108 | axon ensheathment (GO:0008366) | 2.87698470 |
109 | ensheathment of neurons (GO:0007272) | 2.87698470 |
110 | regulation of regulatory T cell differentiation (GO:0045589) | 2.87581208 |
111 | myelination (GO:0042552) | 2.87529743 |
112 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.87290408 |
113 | hydrogen ion transmembrane transport (GO:1902600) | 2.86735850 |
114 | protein maturation by protein folding (GO:0022417) | 2.86632076 |
115 | translation (GO:0006412) | 2.86417567 |
116 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.84011264 |
117 | T cell migration (GO:0072678) | 2.83883749 |
118 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.81626655 |
119 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.81278376 |
120 | negative T cell selection (GO:0043383) | 2.80797899 |
121 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.75830193 |
122 | peptidyl-histidine modification (GO:0018202) | 2.75180340 |
123 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.74501132 |
124 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 2.73811195 |
125 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.72795583 |
126 | positive regulation of ligase activity (GO:0051351) | 2.72474861 |
127 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.72099526 |
128 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.72009047 |
129 | cytochrome complex assembly (GO:0017004) | 2.71458228 |
130 | cellular response to type I interferon (GO:0071357) | 2.69824514 |
131 | type I interferon signaling pathway (GO:0060337) | 2.69824514 |
132 | nucleotide transmembrane transport (GO:1901679) | 2.69722618 |
133 | GDP-mannose metabolic process (GO:0019673) | 2.69083948 |
134 | proton transport (GO:0015992) | 2.68876841 |
135 | response to interleukin-15 (GO:0070672) | 2.68799768 |
136 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.68763421 |
137 | actin nucleation (GO:0045010) | 2.68378675 |
138 | oxidative phosphorylation (GO:0006119) | 2.68315473 |
139 | negative regulation of interleukin-12 production (GO:0032695) | 2.68228545 |
140 | regulation of chronic inflammatory response (GO:0002676) | 2.66365458 |
141 | deoxyribonucleotide catabolic process (GO:0009264) | 2.65919449 |
142 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.65461180 |
143 | response to type I interferon (GO:0034340) | 2.64176589 |
144 | purine nucleotide salvage (GO:0032261) | 2.62572681 |
145 | autophagic vacuole fusion (GO:0000046) | 2.62230965 |
146 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.61819962 |
147 | response to peptidoglycan (GO:0032494) | 2.59068013 |
148 | regulation of activation of Janus kinase activity (GO:0010533) | 2.57935086 |
149 | deoxyribose phosphate catabolic process (GO:0046386) | 2.57894061 |
150 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.57503423 |
151 | positive T cell selection (GO:0043368) | 2.56489119 |
152 | regulation of gamma-delta T cell activation (GO:0046643) | 2.55404786 |
153 | detection of bacterium (GO:0016045) | 2.54933330 |
154 | respiratory burst (GO:0045730) | 2.53748945 |
155 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.53277016 |
156 | base-excision repair, AP site formation (GO:0006285) | 2.53114430 |
157 | regulation of T cell tolerance induction (GO:0002664) | 2.52305351 |
158 | negative regulation of innate immune response (GO:0045824) | 2.52211905 |
159 | positive regulation of B cell differentiation (GO:0045579) | 2.52070675 |
160 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.51380563 |
161 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.51380563 |
162 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.50174041 |
163 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.49285286 |
164 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.48709972 |
165 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.48233908 |
166 | regulation of superoxide anion generation (GO:0032928) | 2.47664055 |
167 | detection of other organism (GO:0098543) | 2.46852154 |
168 | positive regulation of isotype switching (GO:0045830) | 2.46390932 |
169 | granulocyte activation (GO:0036230) | 2.43850506 |
170 | negative regulation of T cell apoptotic process (GO:0070233) | 2.43731409 |
171 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.43697916 |
172 | cellular response to zinc ion (GO:0071294) | 2.43239661 |
173 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.39767564 |
174 | neutrophil activation (GO:0042119) | 2.39528668 |
175 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.36528304 |
176 | cellular response to interferon-beta (GO:0035458) | 2.36414778 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.94765475 |
2 | * NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.97429789 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.76454688 |
4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.73612878 |
5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.16838732 |
6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.11269427 |
7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.08979188 |
8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.53425486 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.44167648 |
10 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.38443070 |
11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.20701365 |
12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.19722778 |
13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.96497931 |
14 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.84390662 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.72488341 |
16 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.70467838 |
17 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.61018244 |
18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.54501979 |
19 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.37341224 |
20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.32908180 |
21 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.28939311 |
22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.05627179 |
23 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.03615521 |
24 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.01992436 |
25 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.99631150 |
26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.99009657 |
27 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.97199103 |
28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.96756958 |
29 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.94296220 |
30 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.94274247 |
31 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.90584791 |
32 | * VDR_21846776_ChIP-Seq_THP-1_Human | 1.87351151 |
33 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.86965368 |
34 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.85479805 |
35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.82014686 |
36 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.80591655 |
37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.75905360 |
38 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.75291533 |
39 | MYB_26560356_Chip-Seq_TH2_Human | 1.75281170 |
40 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.74616097 |
41 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.74391431 |
42 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.73004482 |
43 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.71118932 |
44 | UTX_26944678_Chip-Seq_JUKART_Human | 1.67740033 |
45 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.65874206 |
46 | MAF_26560356_Chip-Seq_TH1_Human | 1.64524224 |
47 | MAF_26560356_Chip-Seq_TH2_Human | 1.62215937 |
48 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.60855826 |
49 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.43494418 |
50 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.43165599 |
51 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.42160380 |
52 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.41892512 |
53 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.40952330 |
54 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.40462466 |
55 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.40223895 |
56 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.39618947 |
57 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.38943258 |
58 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.38697455 |
59 | MYB_26560356_Chip-Seq_TH1_Human | 1.36576234 |
60 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35927605 |
61 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.35463675 |
62 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.35326074 |
63 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.34606942 |
64 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33279347 |
65 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.30814383 |
66 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.29451183 |
67 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.27866535 |
68 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24157099 |
69 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.24022011 |
70 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23512599 |
71 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.22868263 |
72 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.22445321 |
73 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.22435182 |
74 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.21765628 |
75 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.21270180 |
76 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.21133210 |
77 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.20877294 |
78 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.20030279 |
79 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.19690074 |
80 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.19485782 |
81 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.18870142 |
82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.16859314 |
83 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16566613 |
84 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.16522553 |
85 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.15260257 |
86 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.12348327 |
87 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.12170171 |
88 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.11790380 |
89 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.10451266 |
90 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08715680 |
91 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.08588638 |
92 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.07958721 |
93 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.07936334 |
94 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.07273611 |
95 | P68_20966046_ChIP-Seq_HELA_Human | 1.06960970 |
96 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.06717950 |
97 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06529383 |
98 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.06439776 |
99 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.04022012 |
100 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.03735619 |
101 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97886245 |
102 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97728304 |
103 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97484806 |
104 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.96872216 |
105 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.95955142 |
106 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.92512911 |
107 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.91081090 |
108 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.90251397 |
109 | * CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.88174679 |
110 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.88111371 |
111 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.86239739 |
112 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85755781 |
113 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.83313320 |
114 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.80948316 |
115 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.80279339 |
116 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.79141168 |
117 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.78661927 |
118 | * CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.78583124 |
119 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.78559641 |
120 | FUS_26573619_Chip-Seq_HEK293_Human | 0.78353035 |
121 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.78329028 |
122 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.77352557 |
123 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.77072272 |
124 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.76745753 |
125 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.76399748 |
126 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.76168921 |
127 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.75497431 |
128 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.74572379 |
129 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.73868867 |
130 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.73433936 |
131 | TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse | 0.71831071 |
132 | EOMES_21245162_ChIP-Seq_HESCs_Human | 0.70351153 |
133 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.69975732 |
134 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.69041302 |
135 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.68955430 |
136 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.68837884 |
137 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.68353583 |
138 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.67931185 |
139 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.67746494 |
140 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.67324033 |
141 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.66199828 |
142 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.66038399 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 3.69572612 |
2 | MP0001529_abnormal_vocalization | 3.67038805 |
3 | MP0001905_abnormal_dopamine_level | 3.37030776 |
4 | MP0000920_abnormal_myelination | 3.23728383 |
5 | MP0005671_abnormal_response_to | 2.46492890 |
6 | MP0003191_abnormal_cellular_cholesterol | 2.42745152 |
7 | MP0009840_abnormal_foam_cell | 2.36995231 |
8 | MP0003806_abnormal_nucleotide_metabolis | 2.23977314 |
9 | MP0003136_yellow_coat_color | 2.22087386 |
10 | MP0001986_abnormal_taste_sensitivity | 2.19828811 |
11 | MP0000685_abnormal_immune_system | 2.17573092 |
12 | MP0006082_CNS_inflammation | 2.13251877 |
13 | MP0004142_abnormal_muscle_tone | 2.12471067 |
14 | MP0004147_increased_porphyrin_level | 2.09572797 |
15 | MP0003724_increased_susceptibility_to | 2.04839865 |
16 | MP0001348_abnormal_lacrimal_gland | 1.90890685 |
17 | MP0001873_stomach_inflammation | 1.89933828 |
18 | MP0009785_altered_susceptibility_to | 1.87829585 |
19 | MP0002405_respiratory_system_inflammati | 1.85820998 |
20 | MP0001845_abnormal_inflammatory_respons | 1.81724688 |
21 | MP0000372_irregular_coat_pigmentation | 1.80862284 |
22 | MP0005379_endocrine/exocrine_gland_phen | 1.78200841 |
23 | MP0010155_abnormal_intestine_physiology | 1.78160505 |
24 | MP0002736_abnormal_nociception_after | 1.77422979 |
25 | MP0003329_amyloid_beta_deposits | 1.76401460 |
26 | MP0006036_abnormal_mitochondrial_physio | 1.73650952 |
27 | MP0001853_heart_inflammation | 1.73393493 |
28 | MP0005171_absent_coat_pigmentation | 1.69643929 |
29 | MP0005075_abnormal_melanosome_morpholog | 1.69386561 |
30 | MP0001533_abnormal_skeleton_physiology | 1.68901188 |
31 | MP0001835_abnormal_antigen_presentation | 1.68882616 |
32 | MP0001968_abnormal_touch/_nociception | 1.65618883 |
33 | MP0003186_abnormal_redox_activity | 1.65043684 |
34 | MP0005464_abnormal_platelet_physiology | 1.63118833 |
35 | MP0008260_abnormal_autophagy | 1.62322012 |
36 | MP0006276_abnormal_autonomic_nervous | 1.61375641 |
37 | MP0002272_abnormal_nervous_system | 1.57575351 |
38 | MP0005409_darkened_coat_color | 1.53508369 |
39 | MP0002148_abnormal_hypersensitivity_rea | 1.49854551 |
40 | MP0005000_abnormal_immune_tolerance | 1.49440755 |
41 | MP0005387_immune_system_phenotype | 1.48874101 |
42 | MP0001790_abnormal_immune_system | 1.48874101 |
43 | MP0005025_abnormal_response_to | 1.47041698 |
44 | MP0009764_decreased_sensitivity_to | 1.46957287 |
45 | MP0004381_abnormal_hair_follicle | 1.46323728 |
46 | MP0003718_maternal_effect | 1.44724862 |
47 | MP0009379_abnormal_foot_pigmentation | 1.42116600 |
48 | MP0002734_abnormal_mechanical_nocicepti | 1.41001073 |
49 | MP0010386_abnormal_urinary_bladder | 1.40961029 |
50 | MP0000858_altered_metastatic_potential | 1.38286549 |
51 | MP0002163_abnormal_gland_morphology | 1.38265249 |
52 | MP0001970_abnormal_pain_threshold | 1.37509028 |
53 | MP0002735_abnormal_chemical_nociception | 1.36527121 |
54 | MP0003656_abnormal_erythrocyte_physiolo | 1.36451429 |
55 | MP0009333_abnormal_splenocyte_physiolog | 1.36314942 |
56 | MP0002166_altered_tumor_susceptibility | 1.35716691 |
57 | MP0005058_abnormal_lysosome_morphology | 1.34418298 |
58 | MP0004742_abnormal_vestibular_system | 1.34327427 |
59 | MP0004947_skin_inflammation | 1.33615757 |
60 | MP0002723_abnormal_immune_serum | 1.33478996 |
61 | MP0004270_analgesia | 1.33330119 |
62 | MP0005410_abnormal_fertilization | 1.32326097 |
63 | MP0003303_peritoneal_inflammation | 1.32024106 |
64 | MP0002876_abnormal_thyroid_physiology | 1.31094420 |
65 | MP0002064_seizures | 1.30332706 |
66 | MP0000343_altered_response_to | 1.28951942 |
67 | MP0002420_abnormal_adaptive_immunity | 1.26713971 |
68 | MP0009278_abnormal_bone_marrow | 1.26656323 |
69 | MP0005451_abnormal_body_composition | 1.25464808 |
70 | MP0005423_abnormal_somatic_nervous | 1.25202688 |
71 | MP0008875_abnormal_xenobiotic_pharmacok | 1.24588249 |
72 | MP0006035_abnormal_mitochondrial_morpho | 1.23614898 |
73 | MP0001819_abnormal_immune_cell | 1.23089887 |
74 | MP0003075_altered_response_to | 1.20516650 |
75 | MP0002419_abnormal_innate_immunity | 1.18228827 |
76 | MP0002229_neurodegeneration | 1.17722236 |
77 | MP0002277_abnormal_respiratory_mucosa | 1.16366199 |
78 | MP0000703_abnormal_thymus_morphology | 1.16070856 |
79 | MP0001485_abnormal_pinna_reflex | 1.15840693 |
80 | MP0005310_abnormal_salivary_gland | 1.15550518 |
81 | MP0001800_abnormal_humoral_immune | 1.15093082 |
82 | MP0000604_amyloidosis | 1.14362743 |
83 | MP0003763_abnormal_thymus_physiology | 1.13596536 |
84 | MP0002733_abnormal_thermal_nociception | 1.13197654 |
85 | MP0003690_abnormal_glial_cell | 1.12532741 |
86 | MP0002132_abnormal_respiratory_system | 1.11646379 |
87 | MP0003634_abnormal_glial_cell | 1.10580557 |
88 | MP0002452_abnormal_antigen_presenting | 1.07568197 |
89 | MP0003448_altered_tumor_morphology | 1.07276043 |
90 | MP0005174_abnormal_tail_pigmentation | 1.06960254 |
91 | MP0009046_muscle_twitch | 1.05458339 |
92 | MP0002006_tumorigenesis | 1.05082325 |
93 | MP0003866_abnormal_defecation | 1.04920285 |
94 | MP0009745_abnormal_behavioral_response | 1.03904057 |
95 | MP0003786_premature_aging | 1.01078325 |
96 | MP0000716_abnormal_immune_system | 1.00664151 |
97 | MP0001542_abnormal_bone_strength | 0.99279683 |
98 | MP0009763_increased_sensitivity_to | 0.98089893 |
99 | MP0005408_hypopigmentation | 0.97775013 |
100 | MP0002396_abnormal_hematopoietic_system | 0.96706238 |
101 | MP0000490_abnormal_crypts_of | 0.94233531 |
102 | MP0002933_joint_inflammation | 0.94156769 |
103 | MP0005319_abnormal_enzyme/_coenzyme | 0.93578305 |
104 | MP0001727_abnormal_embryo_implantation | 0.93224032 |
105 | MP0005166_decreased_susceptibility_to | 0.92494296 |
106 | MP0003950_abnormal_plasma_membrane | 0.92242185 |
107 | MP0008058_abnormal_DNA_repair | 0.92234865 |
108 | MP0002398_abnormal_bone_marrow | 0.91560429 |
109 | MP0000015_abnormal_ear_pigmentation | 0.90671348 |
110 | MP0000689_abnormal_spleen_morphology | 0.89923352 |
111 | MP0001963_abnormal_hearing_physiology | 0.89009463 |
112 | MP0005365_abnormal_bile_salt | 0.87102165 |
113 | MP0001440_abnormal_grooming_behavior | 0.86974398 |
114 | MP0001764_abnormal_homeostasis | 0.86479853 |
115 | MP0000465_gastrointestinal_hemorrhage | 0.85910972 |
116 | MP0002429_abnormal_blood_cell | 0.85154584 |
117 | MP0002653_abnormal_ependyma_morphology | 0.84794439 |
118 | MP0000681_abnormal_thyroid_gland | 0.84296076 |
119 | MP0001661_extended_life_span | 0.83840246 |
120 | MP0005397_hematopoietic_system_phenotyp | 0.83546991 |
121 | MP0001545_abnormal_hematopoietic_system | 0.83546991 |
122 | MP0002138_abnormal_hepatobiliary_system | 0.83174639 |
123 | MP0009643_abnormal_urine_homeostasis | 0.83005459 |
124 | MP0002019_abnormal_tumor_incidence | 0.82569031 |
125 | MP0005360_urolithiasis | 0.82152830 |
126 | MP0008932_abnormal_embryonic_tissue | 0.82082879 |
127 | MP0002998_abnormal_bone_remodeling | 0.81478196 |
128 | MP0002572_abnormal_emotion/affect_behav | 0.80233815 |
129 | MP0002722_abnormal_immune_system | 0.79972144 |
130 | MP0008469_abnormal_protein_level | 0.77945574 |
131 | MP0002095_abnormal_skin_pigmentation | 0.77704721 |
132 | MP0005386_behavior/neurological_phenoty | 0.77703572 |
133 | MP0004924_abnormal_behavior | 0.77703572 |
134 | MP0000358_abnormal_cell_content/ | 0.77585237 |
135 | MP0002067_abnormal_sensory_capabilities | 0.77449118 |
136 | MP0003172_abnormal_lysosome_physiology | 0.76860938 |
137 | MP0003436_decreased_susceptibility_to | 0.76566551 |
138 | MP0001486_abnormal_startle_reflex | 0.75779034 |
139 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.74679580 |
140 | MP0001663_abnormal_digestive_system | 0.72550993 |
141 | MP0002877_abnormal_melanocyte_morpholog | 0.70918542 |
142 | MP0002139_abnormal_hepatobiliary_system | 0.69757870 |
143 | MP0000609_abnormal_liver_physiology | 0.68895568 |
144 | MP0005390_skeleton_phenotype | 0.65361414 |
145 | MP0005332_abnormal_amino_acid | 0.64144261 |
146 | MP0003300_gastrointestinal_ulcer | 0.62288777 |
147 | MP0002254_reproductive_system_inflammat | 0.61248739 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 5.72490557 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.21540211 |
3 | Mitochondrial inheritance (HP:0001427) | 5.13842927 |
4 | Acute encephalopathy (HP:0006846) | 4.69361845 |
5 | Hepatocellular necrosis (HP:0001404) | 4.67335046 |
6 | Progressive macrocephaly (HP:0004481) | 4.60311959 |
7 | Increased CSF lactate (HP:0002490) | 4.34594133 |
8 | Abnormality of glycolysis (HP:0004366) | 4.31274874 |
9 | Increased serum pyruvate (HP:0003542) | 4.31274874 |
10 | 3-Methylglutaconic aciduria (HP:0003535) | 4.27422747 |
11 | Cerebral hypomyelination (HP:0006808) | 4.08200720 |
12 | Renal Fanconi syndrome (HP:0001994) | 4.06469229 |
13 | Hepatic necrosis (HP:0002605) | 4.03955606 |
14 | Increased hepatocellular lipid droplets (HP:0006565) | 4.03930575 |
15 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.91602291 |
16 | Stomatitis (HP:0010280) | 3.75507577 |
17 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.67845561 |
18 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.67845561 |
19 | Abnormality of glycolipid metabolism (HP:0010969) | 3.67845561 |
20 | Leukodystrophy (HP:0002415) | 3.53954639 |
21 | Lipid accumulation in hepatocytes (HP:0006561) | 3.51508989 |
22 | T lymphocytopenia (HP:0005403) | 3.44545039 |
23 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.44223222 |
24 | Parakeratosis (HP:0001036) | 3.41786047 |
25 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.37470620 |
26 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.37470620 |
27 | Abnormality of T cell number (HP:0011839) | 3.24991281 |
28 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.24497512 |
29 | Increased serum lactate (HP:0002151) | 3.18456513 |
30 | Eczematoid dermatitis (HP:0000976) | 3.13153584 |
31 | Increased intramyocellular lipid droplets (HP:0012240) | 3.12625855 |
32 | Cerebral edema (HP:0002181) | 3.09223558 |
33 | Obstructive lung disease (HP:0006536) | 3.03557781 |
34 | Chronic obstructive pulmonary disease (HP:0006510) | 3.03557781 |
35 | Myositis (HP:0100614) | 3.01847722 |
36 | Respiratory failure (HP:0002878) | 3.01846553 |
37 | Increased IgM level (HP:0003496) | 2.99952347 |
38 | Recurrent fungal infections (HP:0002841) | 2.98000657 |
39 | Lactic acidosis (HP:0003128) | 2.94729667 |
40 | Mediastinal lymphadenopathy (HP:0100721) | 2.83954838 |
41 | Abnormality of T cells (HP:0002843) | 2.83846014 |
42 | Neuroendocrine neoplasm (HP:0100634) | 2.82151168 |
43 | Recurrent bacterial skin infections (HP:0005406) | 2.77332774 |
44 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.76497471 |
45 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.76314538 |
46 | Recurrent cutaneous fungal infections (HP:0011370) | 2.76314538 |
47 | Exertional dyspnea (HP:0002875) | 2.75404004 |
48 | Optic disc pallor (HP:0000543) | 2.75177482 |
49 | Exercise intolerance (HP:0003546) | 2.75110208 |
50 | Neurofibrillary tangles (HP:0002185) | 2.73999199 |
51 | CNS hypomyelination (HP:0003429) | 2.70554957 |
52 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.65535376 |
53 | Retinal dysplasia (HP:0007973) | 2.58428271 |
54 | Combined immunodeficiency (HP:0005387) | 2.57646316 |
55 | Orchitis (HP:0100796) | 2.56130720 |
56 | Abnormality of renal resorption (HP:0011038) | 2.55948182 |
57 | Abnormal number of erythroid precursors (HP:0012131) | 2.54977172 |
58 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.54392432 |
59 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.54392432 |
60 | CNS demyelination (HP:0007305) | 2.53155691 |
61 | Increased muscle lipid content (HP:0009058) | 2.52435861 |
62 | Autoamputation (HP:0001218) | 2.51673455 |
63 | Spastic paraparesis (HP:0002313) | 2.47704632 |
64 | Recurrent viral infections (HP:0004429) | 2.47041153 |
65 | Meningitis (HP:0001287) | 2.43754174 |
66 | Pheochromocytoma (HP:0002666) | 2.40554394 |
67 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.38340154 |
68 | Autoimmune thrombocytopenia (HP:0001973) | 2.36634043 |
69 | Recurrent skin infections (HP:0001581) | 2.36615221 |
70 | Gastrointestinal infarctions (HP:0005244) | 2.36108846 |
71 | Increased cerebral lipofuscin (HP:0011813) | 2.35986779 |
72 | Autoimmune hemolytic anemia (HP:0001890) | 2.35827626 |
73 | Hepatosplenomegaly (HP:0001433) | 2.35424246 |
74 | Chronic diarrhea (HP:0002028) | 2.32279537 |
75 | Dysostosis multiplex (HP:0000943) | 2.30470527 |
76 | Retrobulbar optic neuritis (HP:0100654) | 2.29860793 |
77 | Optic neuritis (HP:0100653) | 2.29860793 |
78 | Respiratory difficulties (HP:0002880) | 2.29689877 |
79 | Microvesicular hepatic steatosis (HP:0001414) | 2.29322729 |
80 | Abnormality of T cell physiology (HP:0011840) | 2.28255047 |
81 | Panhypogammaglobulinemia (HP:0003139) | 2.27316543 |
82 | Pulmonary infiltrates (HP:0002113) | 2.27125720 |
83 | Anorexia (HP:0002039) | 2.25232358 |
84 | Delusions (HP:0000746) | 2.24846185 |
85 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.24111899 |
86 | Petechiae (HP:0000967) | 2.23757103 |
87 | Encephalitis (HP:0002383) | 2.22746806 |
88 | Purpura (HP:0000979) | 2.21610188 |
89 | Abnormality of eosinophils (HP:0001879) | 2.21279657 |
90 | Increased serum ferritin (HP:0003281) | 2.21272857 |
91 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.19373159 |
92 | Prolonged neonatal jaundice (HP:0006579) | 2.19052955 |
93 | Type I transferrin isoform profile (HP:0003642) | 2.17026406 |
94 | Vacuolated lymphocytes (HP:0001922) | 2.16531348 |
95 | Emotional lability (HP:0000712) | 2.15482791 |
96 | Pustule (HP:0200039) | 2.13962783 |
97 | Testicular atrophy (HP:0000029) | 2.13033369 |
98 | Systemic lupus erythematosus (HP:0002725) | 2.10636599 |
99 | Abnormality of the prostate (HP:0008775) | 2.09656546 |
100 | Leukocytosis (HP:0001974) | 2.08880912 |
101 | Ragged-red muscle fibers (HP:0003200) | 2.08421143 |
102 | Generalized aminoaciduria (HP:0002909) | 2.07893107 |
103 | Hypothermia (HP:0002045) | 2.07637951 |
104 | Acute hepatic failure (HP:0006554) | 2.07401167 |
105 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.06892667 |
106 | Hypertensive crisis (HP:0100735) | 2.06515569 |
107 | Hypergammaglobulinemia (HP:0010702) | 2.04618750 |
108 | Macrocytic anemia (HP:0001972) | 2.04210088 |
109 | Loss of speech (HP:0002371) | 2.03729507 |
110 | Agammaglobulinemia (HP:0004432) | 2.02978916 |
111 | Birth length less than 3rd percentile (HP:0003561) | 2.02481954 |
112 | Vasculitis (HP:0002633) | 2.02175423 |
113 | Reduced antithrombin III activity (HP:0001976) | 2.01644854 |
114 | Granulocytopenia (HP:0001913) | 2.00949748 |
115 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.00052183 |
116 | Peripheral hypomyelination (HP:0007182) | 1.99755310 |
117 | Abnormality of placental membranes (HP:0011409) | 1.99486992 |
118 | Amniotic constriction ring (HP:0009775) | 1.99486992 |
119 | Urticaria (HP:0001025) | 1.99330476 |
120 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.98196365 |
121 | Postnatal microcephaly (HP:0005484) | 1.97712465 |
122 | Abnormal pupillary function (HP:0007686) | 1.97453946 |
123 | Hemoptysis (HP:0002105) | 1.95955672 |
124 | Eosinophilia (HP:0001880) | 1.95033594 |
125 | X-linked dominant inheritance (HP:0001423) | 1.94734496 |
126 | Sensory axonal neuropathy (HP:0003390) | 1.93569236 |
127 | Abnormal protein glycosylation (HP:0012346) | 1.93380299 |
128 | Abnormal glycosylation (HP:0012345) | 1.93380299 |
129 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93380299 |
130 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93380299 |
131 | Abnormality of B cell number (HP:0010975) | 1.91581654 |
132 | Cerebral hemorrhage (HP:0001342) | 1.89855634 |
133 | Abnormality of macrophages (HP:0004311) | 1.88695285 |
134 | Progressive neurologic deterioration (HP:0002344) | 1.87757950 |
135 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.87005563 |
136 | Patchy hypopigmentation of hair (HP:0011365) | 1.81531194 |
137 | Abnormality of urine glucose concentration (HP:0011016) | 1.78651617 |
138 | Glycosuria (HP:0003076) | 1.78651617 |
139 | Lethargy (HP:0001254) | 1.77880494 |
140 | Methylmalonic acidemia (HP:0002912) | 1.75929280 |
141 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.75527642 |
142 | Hypoplastic pelvis (HP:0008839) | 1.73806172 |
143 | Hyperphosphaturia (HP:0003109) | 1.73759426 |
144 | IgM deficiency (HP:0002850) | 1.73303076 |
145 | Breast hypoplasia (HP:0003187) | 1.70439884 |
146 | Severe combined immunodeficiency (HP:0004430) | 1.69099380 |
147 | IgG deficiency (HP:0004315) | 1.68341838 |
148 | Gastrointestinal stroma tumor (HP:0100723) | 1.68290943 |
149 | Methylmalonic aciduria (HP:0012120) | 1.67097090 |
150 | Cerebral inclusion bodies (HP:0100314) | 1.65094532 |
151 | Type II lissencephaly (HP:0007260) | 1.63670701 |
152 | Recurrent abscess formation (HP:0002722) | 1.63565126 |
153 | Supranuclear gaze palsy (HP:0000605) | 1.61500293 |
154 | Stridor (HP:0010307) | 1.58953765 |
155 | Aplastic anemia (HP:0001915) | 1.57085944 |
156 | Epiphyseal stippling (HP:0010655) | 1.56479253 |
157 | Abnormal autonomic nervous system physiology (HP:0012332) | 1.54854378 |
158 | Pancytopenia (HP:0001876) | 1.53922011 |
159 | Blindness (HP:0000618) | 1.53378675 |
160 | Slow saccadic eye movements (HP:0000514) | 1.53249902 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 3.54378922 |
2 | STK39 | 3.49684987 |
3 | STK16 | 3.38453185 |
4 | TESK2 | 3.33897981 |
5 | NME2 | 2.80691016 |
6 | LIMK1 | 2.68480018 |
7 | BUB1 | 2.60537308 |
8 | OXSR1 | 2.53749395 |
9 | NME1 | 2.52266117 |
10 | CDK19 | 2.51992698 |
11 | MST4 | 2.43419602 |
12 | ARAF | 2.32908510 |
13 | MAP3K12 | 2.31323198 |
14 | PBK | 2.19694498 |
15 | TBK1 | 2.16277897 |
16 | MAP3K11 | 2.13909186 |
17 | ERN1 | 2.09142296 |
18 | BCR | 2.06605623 |
19 | TYK2 | 2.04368663 |
20 | PIM2 | 1.87803183 |
21 | CSNK1G3 | 1.70259761 |
22 | ADRBK2 | 1.69377600 |
23 | EIF2AK1 | 1.69030840 |
24 | MAPKAPK5 | 1.68803816 |
25 | CSK | 1.66753827 |
26 | PDK2 | 1.64874138 |
27 | VRK1 | 1.63703358 |
28 | WNK4 | 1.61502520 |
29 | MAP4K1 | 1.57481217 |
30 | BMPR1B | 1.56494133 |
31 | CASK | 1.54639998 |
32 | EIF2AK3 | 1.52994848 |
33 | TAOK3 | 1.46950049 |
34 | RIPK4 | 1.42468691 |
35 | KDR | 1.36598967 |
36 | MAP3K14 | 1.34350235 |
37 | KIT | 1.32022586 |
38 | TXK | 1.28429252 |
39 | TLK1 | 1.24567553 |
40 | JAK3 | 1.23816269 |
41 | MYLK | 1.22672918 |
42 | NEK6 | 1.20185266 |
43 | TNIK | 1.20032031 |
44 | DAPK1 | 1.19535574 |
45 | MAP3K3 | 1.18923570 |
46 | SIK3 | 1.18611732 |
47 | IRAK3 | 1.17669161 |
48 | TESK1 | 1.15961270 |
49 | CSNK1G1 | 1.12064548 |
50 | MAP2K3 | 1.08168429 |
51 | PKN1 | 1.04557058 |
52 | MAPKAPK3 | 1.04348967 |
53 | ZAP70 | 1.03991023 |
54 | TSSK6 | 1.03011390 |
55 | CSNK1G2 | 1.02636852 |
56 | CAMK2B | 1.00545500 |
57 | CSNK1A1L | 0.98085504 |
58 | DYRK2 | 0.96566757 |
59 | TAOK2 | 0.94722114 |
60 | CDK8 | 0.94672738 |
61 | NTRK1 | 0.92006482 |
62 | MARK3 | 0.90383890 |
63 | ROCK2 | 0.89921762 |
64 | ZAK | 0.88152882 |
65 | ABL2 | 0.87455458 |
66 | SCYL2 | 0.86238529 |
67 | HCK | 0.85773828 |
68 | TNK2 | 0.84662303 |
69 | TGFBR2 | 0.83837170 |
70 | CCNB1 | 0.82228236 |
71 | LCK | 0.78590852 |
72 | MAP4K2 | 0.78561630 |
73 | SYK | 0.78492328 |
74 | CAMK2G | 0.75318381 |
75 | TAOK1 | 0.73948434 |
76 | BRAF | 0.73518385 |
77 | CAMK2D | 0.70629616 |
78 | MATK | 0.69632587 |
79 | JAK1 | 0.68430574 |
80 | GRK7 | 0.68243638 |
81 | DAPK3 | 0.66484654 |
82 | CLK1 | 0.66302382 |
83 | STK24 | 0.66100300 |
84 | ILK | 0.65356400 |
85 | PRKCQ | 0.65341043 |
86 | GRK5 | 0.65271157 |
87 | CDK14 | 0.63797526 |
88 | UHMK1 | 0.63760462 |
89 | CSF1R | 0.63400712 |
90 | MUSK | 0.63237401 |
91 | MKNK1 | 0.62841104 |
92 | RPS6KA5 | 0.62814038 |
93 | IRAK4 | 0.61726204 |
94 | PIK3CA | 0.60862296 |
95 | FES | 0.60551151 |
96 | EPHB1 | 0.60140207 |
97 | PASK | 0.59349797 |
98 | LYN | 0.57622784 |
99 | ADRBK1 | 0.55588388 |
100 | PAK1 | 0.55439597 |
101 | MAP2K6 | 0.55067542 |
102 | BCKDK | 0.53922364 |
103 | AURKA | 0.53538318 |
104 | PNCK | 0.52838007 |
105 | BMPR2 | 0.52700424 |
106 | BLK | 0.52537992 |
107 | MAP3K6 | 0.52335780 |
108 | CDK18 | 0.51904076 |
109 | MAPKAPK2 | 0.50795992 |
110 | CDK15 | 0.50620880 |
111 | RAF1 | 0.50419904 |
112 | CDK11A | 0.49761474 |
113 | LRRK2 | 0.48709082 |
114 | PRKD2 | 0.48344358 |
115 | WEE1 | 0.48179258 |
116 | TRIM28 | 0.48087217 |
117 | STK10 | 0.48021588 |
118 | GRK6 | 0.47733124 |
119 | PAK4 | 0.47492298 |
120 | FGR | 0.47432624 |
121 | MAP2K7 | 0.45995462 |
122 | CAMKK2 | 0.44900276 |
123 | TEC | 0.44359532 |
124 | IKBKE | 0.42887087 |
125 | JAK2 | 0.42217807 |
126 | IKBKB | 0.41748761 |
127 | PIM1 | 0.41481054 |
128 | CAMK2A | 0.41202812 |
129 | GRK1 | 0.40048602 |
130 | PRKCE | 0.39262144 |
131 | CSNK2A1 | 0.38842456 |
132 | ITK | 0.35884068 |
133 | CSNK2A2 | 0.35868862 |
134 | BTK | 0.35605372 |
135 | CSNK1A1 | 0.34691593 |
136 | MAPK4 | 0.34616080 |
137 | NUAK1 | 0.34189505 |
138 | SMG1 | 0.33711972 |
139 | PRKCI | 0.33305611 |
140 | ACVR1B | 0.30806590 |
141 | FYN | 0.30286248 |
142 | EIF2AK2 | 0.30265634 |
143 | PRKCD | 0.29688655 |
144 | MAPK11 | 0.27217674 |
145 | MAP3K5 | 0.26964154 |
146 | IGF1R | 0.25897712 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.58585502 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.45418939 |
3 | Protein export_Homo sapiens_hsa03060 | 3.99133028 |
4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.84749719 |
5 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 3.57996800 |
6 | Ribosome_Homo sapiens_hsa03010 | 3.50362179 |
7 | RNA polymerase_Homo sapiens_hsa03020 | 3.33758756 |
8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.81437764 |
9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.61402316 |
10 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.52857125 |
11 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.39399030 |
12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.27244868 |
13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.06448061 |
14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.82478285 |
15 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.73666558 |
16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.68970510 |
17 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.56346262 |
18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.55760383 |
19 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.51499364 |
20 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.48720825 |
21 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.48339954 |
22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.40614079 |
23 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.40318621 |
24 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.40112583 |
25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.36369219 |
26 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.35537973 |
27 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.33518241 |
28 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.33079206 |
29 | Mismatch repair_Homo sapiens_hsa03430 | 1.32004827 |
30 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.26373396 |
31 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.23350107 |
32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23338431 |
33 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.22658647 |
34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.19429210 |
35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.19390250 |
36 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.17460637 |
37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.13363189 |
38 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.12722970 |
39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.12524005 |
40 | DNA replication_Homo sapiens_hsa03030 | 1.11722817 |
41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.11195243 |
42 | Allograft rejection_Homo sapiens_hsa05330 | 1.11150797 |
43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.11056245 |
44 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.09878215 |
45 | Homologous recombination_Homo sapiens_hsa03440 | 1.06753337 |
46 | Measles_Homo sapiens_hsa05162 | 1.04741436 |
47 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.04407264 |
48 | Tuberculosis_Homo sapiens_hsa05152 | 1.04062596 |
49 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.01943427 |
50 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.01252106 |
51 | Purine metabolism_Homo sapiens_hsa00230 | 0.97882711 |
52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.97517996 |
53 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.96770804 |
54 | Spliceosome_Homo sapiens_hsa03040 | 0.95602545 |
55 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.93283236 |
56 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.93010166 |
57 | Sulfur relay system_Homo sapiens_hsa04122 | 0.92797556 |
58 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.88307406 |
59 | Histidine metabolism_Homo sapiens_hsa00340 | 0.87486691 |
60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.87364878 |
61 | Galactose metabolism_Homo sapiens_hsa00052 | 0.85675168 |
62 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.81900851 |
63 | Other glycan degradation_Homo sapiens_hsa00511 | 0.80136941 |
64 | Base excision repair_Homo sapiens_hsa03410 | 0.79791361 |
65 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.78766139 |
66 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.78350238 |
67 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77555500 |
68 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.77229626 |
69 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.76915810 |
70 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.76437175 |
71 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.75516037 |
72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.75273866 |
73 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.69568969 |
74 | Influenza A_Homo sapiens_hsa05164 | 0.68139654 |
75 | Phagosome_Homo sapiens_hsa04145 | 0.65737414 |
76 | Asthma_Homo sapiens_hsa05310 | 0.61838990 |
77 | Lysosome_Homo sapiens_hsa04142 | 0.59441696 |
78 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.58962871 |
79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58637009 |
80 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.57304849 |
81 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.55869384 |
82 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.54366343 |
83 | Peroxisome_Homo sapiens_hsa04146 | 0.54043691 |
84 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.52924308 |
85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.52794862 |
86 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.52177279 |
87 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51823373 |
88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.50954643 |
89 | Apoptosis_Homo sapiens_hsa04210 | 0.49210902 |
90 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.48880173 |
91 | Shigellosis_Homo sapiens_hsa05131 | 0.48695985 |
92 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.48658094 |
93 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.48588332 |
94 | Malaria_Homo sapiens_hsa05144 | 0.47453525 |
95 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47340025 |
96 | RNA degradation_Homo sapiens_hsa03018 | 0.47243884 |
97 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.45285086 |
98 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44423895 |
99 | RNA transport_Homo sapiens_hsa03013 | 0.44253418 |
100 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.43487937 |
101 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.42796110 |
102 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.42761716 |
103 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.41211321 |
104 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39967710 |
105 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39163625 |
106 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.38547298 |
107 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.38305893 |
108 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.38191099 |
109 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.37759471 |
110 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.37682809 |
111 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36555676 |
112 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.36390474 |
113 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.35182709 |
114 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.33931890 |
115 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.33572350 |
116 | HTLV-I infection_Homo sapiens_hsa05166 | 0.33265890 |
117 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32903294 |
118 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.32389305 |
119 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.29852242 |
120 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.27537916 |
121 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.27382285 |
122 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.25722457 |
123 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.24219218 |
124 | Pertussis_Homo sapiens_hsa05133 | 0.23635954 |
125 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.21530529 |
126 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.17468075 |
127 | Carbon metabolism_Homo sapiens_hsa01200 | 0.17366763 |
128 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.16662022 |
129 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.16476482 |
130 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.13924311 |
131 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.13813812 |
132 | Legionellosis_Homo sapiens_hsa05134 | 0.12546268 |
133 | Salmonella infection_Homo sapiens_hsa05132 | 0.12032900 |
134 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.11981924 |
135 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.11610465 |