

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | kinetochore assembly (GO:0051382) | 5.55693504 |
| 2 | regulation of centriole replication (GO:0046599) | 5.32120340 |
| 3 | kinetochore organization (GO:0051383) | 5.26264451 |
| 4 | proteasome assembly (GO:0043248) | 5.16604016 |
| 5 | viral mRNA export from host cell nucleus (GO:0046784) | 4.73892158 |
| 6 | positive regulation of megakaryocyte differentiation (GO:0045654) | 4.53390415 |
| 7 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.53272436 |
| 8 | protein K6-linked ubiquitination (GO:0085020) | 4.42238543 |
| 9 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.29781146 |
| 10 | DNA strand elongation (GO:0022616) | 4.23919810 |
| 11 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 4.22100117 |
| 12 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 4.22100117 |
| 13 | protein localization to kinetochore (GO:0034501) | 4.21213443 |
| 14 | nucleobase biosynthetic process (GO:0046112) | 4.15376367 |
| 15 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 4.12770789 |
| 16 | DNA ligation (GO:0006266) | 4.08953439 |
| 17 | meiotic chromosome segregation (GO:0045132) | 4.03481818 |
| 18 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.99818246 |
| 19 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.99818246 |
| 20 | telomere maintenance via recombination (GO:0000722) | 3.96381606 |
| 21 | synapsis (GO:0007129) | 3.96044564 |
| 22 | mitotic recombination (GO:0006312) | 3.94572737 |
| 23 | mitotic nuclear envelope disassembly (GO:0007077) | 3.91999566 |
| 24 | GMP metabolic process (GO:0046037) | 3.91264756 |
| 25 | purine nucleobase biosynthetic process (GO:0009113) | 3.89959844 |
| 26 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.87098138 |
| 27 | nuclear pore organization (GO:0006999) | 3.80636566 |
| 28 | DNA unwinding involved in DNA replication (GO:0006268) | 3.79041446 |
| 29 | DNA topological change (GO:0006265) | 3.75342505 |
| 30 | DNA replication checkpoint (GO:0000076) | 3.72108881 |
| 31 | nuclear pore complex assembly (GO:0051292) | 3.68413142 |
| 32 | membrane disassembly (GO:0030397) | 3.60012645 |
| 33 | nuclear envelope disassembly (GO:0051081) | 3.60012645 |
| 34 | chromatin remodeling at centromere (GO:0031055) | 3.58903645 |
| 35 | negative regulation of mRNA processing (GO:0050686) | 3.58005960 |
| 36 | mitotic sister chromatid cohesion (GO:0007064) | 3.57564059 |
| 37 | DNA double-strand break processing (GO:0000729) | 3.56315522 |
| 38 | metaphase plate congression (GO:0051310) | 3.56005666 |
| 39 | mitotic metaphase plate congression (GO:0007080) | 3.53546976 |
| 40 | mitotic sister chromatid segregation (GO:0000070) | 3.51618685 |
| 41 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.51497830 |
| 42 | DNA replication initiation (GO:0006270) | 3.51144036 |
| 43 | CENP-A containing nucleosome assembly (GO:0034080) | 3.49065691 |
| 44 | establishment of integrated proviral latency (GO:0075713) | 3.46646492 |
| 45 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.45267500 |
| 46 | sister chromatid segregation (GO:0000819) | 3.43935183 |
| 47 | resolution of meiotic recombination intermediates (GO:0000712) | 3.42768663 |
| 48 | regulation of centrosome duplication (GO:0010824) | 3.41209411 |
| 49 | regulation of centrosome cycle (GO:0046605) | 3.36794593 |
| 50 | protein localization to chromosome, centromeric region (GO:0071459) | 3.34044510 |
| 51 | IMP biosynthetic process (GO:0006188) | 3.32952321 |
| 52 | replication fork processing (GO:0031297) | 3.30370090 |
| 53 | branching involved in prostate gland morphogenesis (GO:0060442) | 3.29992183 |
| 54 | maturation of 5.8S rRNA (GO:0000460) | 3.25692389 |
| 55 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.24812604 |
| 56 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.24042990 |
| 57 | regulation of translational fidelity (GO:0006450) | 3.18516100 |
| 58 | histone exchange (GO:0043486) | 3.18425544 |
| 59 | exocrine pancreas development (GO:0031017) | 3.17923476 |
| 60 | centriole replication (GO:0007099) | 3.12198891 |
| 61 | folic acid metabolic process (GO:0046655) | 3.10983406 |
| 62 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.10474975 |
| 63 | non-recombinational repair (GO:0000726) | 3.10474975 |
| 64 | telomere maintenance via telomere lengthening (GO:0010833) | 3.10356716 |
| 65 | chromosome segregation (GO:0007059) | 3.07591132 |
| 66 | double-strand break repair via homologous recombination (GO:0000724) | 3.07463031 |
| 67 | recombinational repair (GO:0000725) | 3.05722989 |
| 68 | mitotic chromosome condensation (GO:0007076) | 3.04793623 |
| 69 | negative regulation of mRNA metabolic process (GO:1903312) | 3.02145656 |
| 70 | microtubule depolymerization (GO:0007019) | 3.02107457 |
| 71 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.01695107 |
| 72 | negative regulation of RNA splicing (GO:0033119) | 2.89667561 |
| 73 | DNA synthesis involved in DNA repair (GO:0000731) | 2.88095934 |
| 74 | pore complex assembly (GO:0046931) | 2.87151412 |
| 75 | regulation of mitotic spindle organization (GO:0060236) | 2.86830437 |
| 76 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.86461370 |
| 77 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.86286472 |
| 78 | IMP metabolic process (GO:0046040) | 2.84372091 |
| 79 | cell cycle G1/S phase transition (GO:0044843) | 2.76374068 |
| 80 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.76374068 |
| 81 | DNA strand renaturation (GO:0000733) | 2.75617954 |
| 82 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.75400957 |
| 83 | mitotic cell cycle (GO:0000278) | 2.75087182 |
| 84 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.74595975 |
| 85 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.72827620 |
| 86 | pseudouridine synthesis (GO:0001522) | 2.70862442 |
| 87 | rRNA processing (GO:0006364) | 2.70570642 |
| 88 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.70243134 |
| 89 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.70243134 |
| 90 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.68677441 |
| 91 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.68677441 |
| 92 | protein localization to chromosome (GO:0034502) | 2.66919783 |
| 93 | regulation of double-strand break repair (GO:2000779) | 2.66872297 |
| 94 | chaperone-mediated protein transport (GO:0072321) | 2.66795513 |
| 95 | rRNA metabolic process (GO:0016072) | 2.66747493 |
| 96 | RNA export from nucleus (GO:0006405) | 2.66687337 |
| 97 | establishment of chromosome localization (GO:0051303) | 2.66655626 |
| 98 | chromosome organization involved in meiosis (GO:0070192) | 2.65775669 |
| 99 | regulation of exit from mitosis (GO:0007096) | 2.64820964 |
| 100 | homocysteine metabolic process (GO:0050667) | 2.64583634 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.99324419 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.45559173 |
| 3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.01502346 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.69368147 |
| 5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.65860212 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.41633793 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.85851977 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.80570411 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.80482460 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.77774089 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.71454162 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.68466189 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.51294685 |
| 14 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.45090369 |
| 15 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.41493199 |
| 16 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.38173163 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.35176596 |
| 18 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.32971735 |
| 19 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.31086654 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.27230322 |
| 21 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.24501149 |
| 22 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.21720909 |
| 23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.11251911 |
| 24 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.05364709 |
| 25 | E2F7_22180533_ChIP-Seq_HELA_Human | 10.0371830 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96911907 |
| 27 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.93069532 |
| 28 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.92706327 |
| 29 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.86715572 |
| 30 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.82672860 |
| 31 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.81680489 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79779786 |
| 33 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.78531532 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.76108464 |
| 35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.74802166 |
| 36 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.74648750 |
| 37 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.74244866 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.73319243 |
| 39 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.69897076 |
| 40 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.69374984 |
| 41 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.63341406 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.63273344 |
| 43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59459590 |
| 44 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.56438965 |
| 45 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.56054640 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52540849 |
| 47 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.50613669 |
| 48 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49142749 |
| 49 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.45445360 |
| 50 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.43201584 |
| 51 | FUS_26573619_Chip-Seq_HEK293_Human | 1.42995474 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.39605541 |
| 53 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.36196418 |
| 54 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.32978450 |
| 55 | VDR_22108803_ChIP-Seq_LS180_Human | 1.30387164 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.28909745 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.24894081 |
| 58 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.24245370 |
| 59 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.23925574 |
| 60 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.20095740 |
| 61 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.16495444 |
| 62 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.16086202 |
| 63 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16038748 |
| 64 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.13511517 |
| 65 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.06182555 |
| 66 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.05007413 |
| 67 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.02712040 |
| 68 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.00095430 |
| 69 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.98109219 |
| 70 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.96040870 |
| 71 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.94178305 |
| 72 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.88853625 |
| 73 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.88571496 |
| 74 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.87689246 |
| 75 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.86639806 |
| 76 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.86579036 |
| 77 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.86096080 |
| 78 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.84865745 |
| 79 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.81984045 |
| 80 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.78900731 |
| 81 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.76437886 |
| 82 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.76232405 |
| 83 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.76228859 |
| 84 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.76168026 |
| 85 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.75418837 |
| 86 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.74114038 |
| 87 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72041211 |
| 88 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.70479501 |
| 89 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.70229675 |
| 90 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.69563831 |
| 91 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.68435110 |
| 92 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.67895960 |
| 93 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.67856491 |
| 94 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.67526883 |
| 95 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.65968108 |
| 96 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.65195299 |
| 97 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.65155573 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.63721711 |
| 99 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.63721711 |
| 100 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.62659815 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002254_reproductive_system_inflammat | 6.46505103 |
| 2 | MP0010094_abnormal_chromosome_stability | 4.48285015 |
| 3 | MP0008058_abnormal_DNA_repair | 4.00165575 |
| 4 | MP0003111_abnormal_nucleus_morphology | 3.27360680 |
| 5 | MP0001346_abnormal_lacrimal_gland | 3.26573064 |
| 6 | MP0003136_yellow_coat_color | 3.11611841 |
| 7 | MP0001873_stomach_inflammation | 2.79707197 |
| 8 | MP0005377_hearing/vestibular/ear_phenot | 2.69340319 |
| 9 | MP0003878_abnormal_ear_physiology | 2.69340319 |
| 10 | MP0004957_abnormal_blastocyst_morpholog | 2.60881134 |
| 11 | MP0002876_abnormal_thyroid_physiology | 2.48155038 |
| 12 | MP0003693_abnormal_embryo_hatching | 2.43903609 |
| 13 | MP0003077_abnormal_cell_cycle | 2.37823455 |
| 14 | MP0009697_abnormal_copulation | 2.23326277 |
| 15 | MP0003786_premature_aging | 2.21607118 |
| 16 | MP0008995_early_reproductive_senescence | 2.20657400 |
| 17 | MP0000427_abnormal_hair_cycle | 2.01838543 |
| 18 | MP0000537_abnormal_urethra_morphology | 1.94745090 |
| 19 | MP0008877_abnormal_DNA_methylation | 1.93763410 |
| 20 | MP0000383_abnormal_hair_follicle | 1.93492150 |
| 21 | MP0005187_abnormal_penis_morphology | 1.91515895 |
| 22 | MP0008057_abnormal_DNA_replication | 1.90397912 |
| 23 | MP0000516_abnormal_urinary_system | 1.86554969 |
| 24 | MP0005367_renal/urinary_system_phenotyp | 1.86554969 |
| 25 | MP0008007_abnormal_cellular_replicative | 1.85167310 |
| 26 | MP0001293_anophthalmia | 1.81754288 |
| 27 | MP0003315_abnormal_perineum_morphology | 1.80150866 |
| 28 | MP0006035_abnormal_mitochondrial_morpho | 1.79923833 |
| 29 | MP0008932_abnormal_embryonic_tissue | 1.77532362 |
| 30 | MP0001348_abnormal_lacrimal_gland | 1.76246436 |
| 31 | MP0003937_abnormal_limbs/digits/tail_de | 1.70334157 |
| 32 | MP0006036_abnormal_mitochondrial_physio | 1.68259948 |
| 33 | MP0002396_abnormal_hematopoietic_system | 1.66084502 |
| 34 | MP0000015_abnormal_ear_pigmentation | 1.58262602 |
| 35 | MP0002095_abnormal_skin_pigmentation | 1.55570956 |
| 36 | MP0003950_abnormal_plasma_membrane | 1.54049366 |
| 37 | MP0010307_abnormal_tumor_latency | 1.47770935 |
| 38 | MP0008872_abnormal_physiological_respon | 1.46517823 |
| 39 | MP0002210_abnormal_sex_determination | 1.43233367 |
| 40 | MP0005075_abnormal_melanosome_morpholog | 1.38648770 |
| 41 | MP0000372_irregular_coat_pigmentation | 1.37106110 |
| 42 | MP0000647_abnormal_sebaceous_gland | 1.30393373 |
| 43 | MP0001929_abnormal_gametogenesis | 1.29100535 |
| 44 | MP0005197_abnormal_uvea_morphology | 1.24452644 |
| 45 | MP0001697_abnormal_embryo_size | 1.22327062 |
| 46 | MP0001730_embryonic_growth_arrest | 1.21867003 |
| 47 | MP0002938_white_spotting | 1.19067291 |
| 48 | MP0001145_abnormal_male_reproductive | 1.15400235 |
| 49 | MP0006292_abnormal_olfactory_placode | 1.11961388 |
| 50 | MP0003718_maternal_effect | 1.11481406 |
| 51 | MP0004782_abnormal_surfactant_physiolog | 1.08291984 |
| 52 | MP0000538_abnormal_urinary_bladder | 1.08265696 |
| 53 | MP0003698_abnormal_male_reproductive | 1.07235193 |
| 54 | MP0003186_abnormal_redox_activity | 1.07203308 |
| 55 | MP0004381_abnormal_hair_follicle | 1.05368376 |
| 56 | MP0000653_abnormal_sex_gland | 1.05265735 |
| 57 | MP0005310_abnormal_salivary_gland | 0.95843960 |
| 58 | MP0005645_abnormal_hypothalamus_physiol | 0.94265832 |
| 59 | MP0002085_abnormal_embryonic_tissue | 0.93912330 |
| 60 | MP0005380_embryogenesis_phenotype | 0.93363200 |
| 61 | MP0001672_abnormal_embryogenesis/_devel | 0.93363200 |
| 62 | MP0000350_abnormal_cell_proliferation | 0.93108047 |
| 63 | MP0004043_abnormal_pH_regulation | 0.91913956 |
| 64 | MP0000358_abnormal_cell_content/ | 0.90177158 |
| 65 | MP0005410_abnormal_fertilization | 0.89168469 |
| 66 | MP0003567_abnormal_fetal_cardiomyocyte | 0.88588519 |
| 67 | MP0005408_hypopigmentation | 0.88587203 |
| 68 | MP0001119_abnormal_female_reproductive | 0.88385480 |
| 69 | MP0004197_abnormal_fetal_growth/weight/ | 0.87298701 |
| 70 | MP0010678_abnormal_skin_adnexa | 0.85462635 |
| 71 | MP0003984_embryonic_growth_retardation | 0.84776800 |
| 72 | MP0002080_prenatal_lethality | 0.83548505 |
| 73 | MP0002088_abnormal_embryonic_growth/wei | 0.78848697 |
| 74 | MP0000313_abnormal_cell_death | 0.77330836 |
| 75 | MP0002098_abnormal_vibrissa_morphology | 0.76560160 |
| 76 | MP0005647_abnormal_sex_gland | 0.75954490 |
| 77 | MP0000467_abnormal_esophagus_morphology | 0.75618148 |
| 78 | MP0009672_abnormal_birth_weight | 0.74965734 |
| 79 | MP0002086_abnormal_extraembryonic_tissu | 0.74285116 |
| 80 | MP0005084_abnormal_gallbladder_morpholo | 0.72422351 |
| 81 | MP0003943_abnormal_hepatobiliary_system | 0.71600943 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.70703606 |
| 83 | MP0001177_atelectasis | 0.70370308 |
| 84 | MP0003646_muscle_fatigue | 0.69420998 |
| 85 | MP0008770_decreased_survivor_rate | 0.68691129 |
| 86 | MP0009379_abnormal_foot_pigmentation | 0.67800171 |
| 87 | MP0002161_abnormal_fertility/fecundity | 0.67704210 |
| 88 | MP0002084_abnormal_developmental_patter | 0.67634267 |
| 89 | MP0001661_extended_life_span | 0.66144096 |
| 90 | MP0010352_gastrointestinal_tract_polyps | 0.64885225 |
| 91 | MP0000566_synostosis | 0.61327309 |
| 92 | MP0000613_abnormal_salivary_gland | 0.60723469 |
| 93 | MP0002075_abnormal_coat/hair_pigmentati | 0.59749695 |
| 94 | MP0002233_abnormal_nose_morphology | 0.59114091 |
| 95 | MP0000639_abnormal_adrenal_gland | 0.59104610 |
| 96 | MP0003938_abnormal_ear_development | 0.58877519 |
| 97 | MP0010030_abnormal_orbit_morphology | 0.58170520 |
| 98 | MP0009278_abnormal_bone_marrow | 0.58075761 |
| 99 | MP0001905_abnormal_dopamine_level | 0.57791090 |
| 100 | MP0003699_abnormal_female_reproductive | 0.57697023 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased circulating renin level (HP:0000848) | 6.63211423 |
| 2 | Short 1st metacarpal (HP:0010034) | 5.25701004 |
| 3 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 5.25701004 |
| 4 | Bilateral sensorineural hearing impairment (HP:0008619) | 5.16846571 |
| 5 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.07318764 |
| 6 | Hypokalemic alkalosis (HP:0001949) | 4.57448916 |
| 7 | Abnormality of the 1st metacarpal (HP:0010009) | 4.56762787 |
| 8 | Chromsome breakage (HP:0040012) | 4.51028610 |
| 9 | Hypomagnesemia (HP:0002917) | 4.45190089 |
| 10 | Tetany (HP:0001281) | 4.41593095 |
| 11 | Septate vagina (HP:0001153) | 4.33641143 |
| 12 | Paralysis (HP:0003470) | 4.09906322 |
| 13 | Abnormality of magnesium homeostasis (HP:0004921) | 3.82951567 |
| 14 | Abnormal drinking behavior (HP:0030082) | 3.81852703 |
| 15 | Polydipsia (HP:0001959) | 3.81852703 |
| 16 | Abnormality of the ileum (HP:0001549) | 3.46684479 |
| 17 | Meckel diverticulum (HP:0002245) | 3.38838795 |
| 18 | Abnormality of the preputium (HP:0100587) | 3.37102108 |
| 19 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.21546735 |
| 20 | Short phalanx of the thumb (HP:0009660) | 3.20738693 |
| 21 | Abnormal tarsal ossification (HP:0008369) | 3.13422380 |
| 22 | Amelogenesis imperfecta (HP:0000705) | 3.04849927 |
| 23 | Abnormality of chromosome stability (HP:0003220) | 3.04733168 |
| 24 | Polyuria (HP:0000103) | 2.79757987 |
| 25 | Dyschromatopsia (HP:0007641) | 2.79135636 |
| 26 | Abnormality of renin-angiotensin system (HP:0000847) | 2.77229198 |
| 27 | Renal tubular acidosis (HP:0001947) | 2.70971679 |
| 28 | Duodenal stenosis (HP:0100867) | 2.69055097 |
| 29 | Small intestinal stenosis (HP:0012848) | 2.69055097 |
| 30 | Abnormality of the 2nd finger (HP:0004100) | 2.68590951 |
| 31 | Spontaneous abortion (HP:0005268) | 2.64722647 |
| 32 | Sloping forehead (HP:0000340) | 2.61270406 |
| 33 | Asplenia (HP:0001746) | 2.53003600 |
| 34 | Short thumb (HP:0009778) | 2.52865540 |
| 35 | Long clavicles (HP:0000890) | 2.46935702 |
| 36 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 2.45625150 |
| 37 | Abnormality of the carotid arteries (HP:0005344) | 2.43049078 |
| 38 | Abnormality of glycolysis (HP:0004366) | 2.42528355 |
| 39 | Myelodysplasia (HP:0002863) | 2.40956078 |
| 40 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.38883588 |
| 41 | Horseshoe kidney (HP:0000085) | 2.35851340 |
| 42 | Cerebellar dysplasia (HP:0007033) | 2.33150327 |
| 43 | Birth length less than 3rd percentile (HP:0003561) | 2.29625956 |
| 44 | Alkalosis (HP:0001948) | 2.28180100 |
| 45 | Short middle phalanx of finger (HP:0005819) | 2.27684478 |
| 46 | Abnormality of the labia minora (HP:0012880) | 2.27040653 |
| 47 | Abnormal foot bone ossification (HP:0010675) | 2.25288071 |
| 48 | Abnormal urine output (HP:0012590) | 2.23977912 |
| 49 | Duplicated collecting system (HP:0000081) | 2.23352680 |
| 50 | High anterior hairline (HP:0009890) | 2.20842572 |
| 51 | Increased serum pyruvate (HP:0003542) | 2.14553608 |
| 52 | Septo-optic dysplasia (HP:0100842) | 2.14186349 |
| 53 | Abnormality of the duodenum (HP:0002246) | 2.13811722 |
| 54 | Ectopic kidney (HP:0000086) | 2.10592984 |
| 55 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.10190571 |
| 56 | Abnormality of cochlea (HP:0000375) | 2.06803985 |
| 57 | Colon cancer (HP:0003003) | 2.06185108 |
| 58 | Short 5th finger (HP:0009237) | 2.05306716 |
| 59 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.05216753 |
| 60 | Abnormality of the renal collecting system (HP:0004742) | 2.04555362 |
| 61 | Patellar aplasia (HP:0006443) | 2.04112049 |
| 62 | Clubbing of toes (HP:0100760) | 2.03865061 |
| 63 | Delayed CNS myelination (HP:0002188) | 2.02192251 |
| 64 | 3-Methylglutaconic aciduria (HP:0003535) | 2.01692055 |
| 65 | Hypoparathyroidism (HP:0000829) | 1.98478954 |
| 66 | Molar tooth sign on MRI (HP:0002419) | 1.97991071 |
| 67 | Abnormality of midbrain morphology (HP:0002418) | 1.97991071 |
| 68 | Increased nuchal translucency (HP:0010880) | 1.95137341 |
| 69 | Ureteral duplication (HP:0000073) | 1.93618437 |
| 70 | Recurrent cutaneous fungal infections (HP:0011370) | 1.92924661 |
| 71 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.92924661 |
| 72 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.90460666 |
| 73 | Type I transferrin isoform profile (HP:0003642) | 1.86737712 |
| 74 | Nephronophthisis (HP:0000090) | 1.83974305 |
| 75 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.82011571 |
| 76 | Abnormality of renal excretion (HP:0011036) | 1.81006564 |
| 77 | Hypokalemia (HP:0002900) | 1.78903209 |
| 78 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.78900257 |
| 79 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.78900257 |
| 80 | Ureteral stenosis (HP:0000071) | 1.74436457 |
| 81 | Morphological abnormality of the inner ear (HP:0011390) | 1.74299149 |
| 82 | Cleft eyelid (HP:0000625) | 1.73190851 |
| 83 | Neoplasm of the adrenal cortex (HP:0100641) | 1.71911492 |
| 84 | Generalized muscle weakness (HP:0003324) | 1.71694974 |
| 85 | High pitched voice (HP:0001620) | 1.70685333 |
| 86 | Renal tubular dysfunction (HP:0000124) | 1.70646108 |
| 87 | Methylmalonic acidemia (HP:0002912) | 1.70585031 |
| 88 | Unilateral renal agenesis (HP:0000122) | 1.68754256 |
| 89 | Cortical dysplasia (HP:0002539) | 1.68710353 |
| 90 | Cafe-au-lait spot (HP:0000957) | 1.67715149 |
| 91 | Arteriovenous malformation (HP:0100026) | 1.67462167 |
| 92 | Abnormality of DNA repair (HP:0003254) | 1.66792341 |
| 93 | Flat capital femoral epiphysis (HP:0003370) | 1.66644033 |
| 94 | Cholelithiasis (HP:0001081) | 1.66009567 |
| 95 | Abnormality of dental color (HP:0011073) | 1.65305765 |
| 96 | Absent radius (HP:0003974) | 1.64515209 |
| 97 | Abnormality of homocysteine metabolism (HP:0010919) | 1.63887049 |
| 98 | Homocystinuria (HP:0002156) | 1.63887049 |
| 99 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.61454321 |
| 100 | Blepharitis (HP:0000498) | 1.61069356 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 8.68913909 |
| 2 | STK39 | 8.33916425 |
| 3 | OXSR1 | 6.09047735 |
| 4 | TNIK | 2.44278341 |
| 5 | CDC7 | 2.24931915 |
| 6 | VRK2 | 2.23121610 |
| 7 | PLK4 | 1.97212311 |
| 8 | TTK | 1.79886892 |
| 9 | EIF2AK1 | 1.75248960 |
| 10 | EIF2AK3 | 1.64376501 |
| 11 | PRKD3 | 1.60706718 |
| 12 | TAF1 | 1.51043737 |
| 13 | NEK1 | 1.48302622 |
| 14 | WEE1 | 1.45651689 |
| 15 | PLK2 | 1.40240604 |
| 16 | NUAK1 | 1.32461954 |
| 17 | BRSK2 | 1.31559206 |
| 18 | CCNB1 | 1.28991173 |
| 19 | PLK3 | 1.27515576 |
| 20 | MKNK2 | 1.22983033 |
| 21 | CHEK2 | 1.19596886 |
| 22 | ATR | 1.19183849 |
| 23 | MKNK1 | 1.16808674 |
| 24 | PBK | 1.13727581 |
| 25 | PLK1 | 1.07227123 |
| 26 | VRK1 | 1.04803745 |
| 27 | EIF2AK2 | 1.00520285 |
| 28 | NME1 | 0.99590365 |
| 29 | MAP2K7 | 0.99232619 |
| 30 | BUB1 | 0.92271158 |
| 31 | SRPK1 | 0.90973499 |
| 32 | BRD4 | 0.89882297 |
| 33 | TSSK6 | 0.86948875 |
| 34 | MST4 | 0.83899446 |
| 35 | MAP3K4 | 0.82077057 |
| 36 | ZAK | 0.77359994 |
| 37 | STK16 | 0.76238346 |
| 38 | ERBB4 | 0.75271810 |
| 39 | STK10 | 0.73042660 |
| 40 | BRSK1 | 0.69801922 |
| 41 | MAP3K6 | 0.68705863 |
| 42 | AURKB | 0.66850957 |
| 43 | BMPR1B | 0.63963038 |
| 44 | TNK2 | 0.61822379 |
| 45 | PIK3CA | 0.61481470 |
| 46 | CHEK1 | 0.58300638 |
| 47 | PRKG2 | 0.54924930 |
| 48 | LATS2 | 0.54753871 |
| 49 | PTK2B | 0.54350490 |
| 50 | ATM | 0.52760090 |
| 51 | NEK2 | 0.52206164 |
| 52 | DYRK2 | 0.49551290 |
| 53 | CDK8 | 0.48274726 |
| 54 | RPS6KB2 | 0.46346696 |
| 55 | CDK1 | 0.46345724 |
| 56 | CDK12 | 0.46194437 |
| 57 | TIE1 | 0.43324169 |
| 58 | WNK3 | 0.42563674 |
| 59 | DAPK1 | 0.41424477 |
| 60 | PKN2 | 0.40069192 |
| 61 | AKT3 | 0.39308008 |
| 62 | NLK | 0.38916557 |
| 63 | CAMK1D | 0.38605786 |
| 64 | PKN1 | 0.37172303 |
| 65 | DMPK | 0.36415260 |
| 66 | STK4 | 0.34989066 |
| 67 | CSNK2A1 | 0.32942112 |
| 68 | FLT3 | 0.32664000 |
| 69 | CDK3 | 0.31363775 |
| 70 | ALK | 0.31259735 |
| 71 | RET | 0.31160724 |
| 72 | CDK7 | 0.30198338 |
| 73 | PINK1 | 0.30192958 |
| 74 | MAPK13 | 0.29539864 |
| 75 | CDK2 | 0.29283059 |
| 76 | PRKDC | 0.28294452 |
| 77 | PDK2 | 0.27613823 |
| 78 | CSNK2A2 | 0.25297303 |
| 79 | FGFR1 | 0.24408462 |
| 80 | MAP2K4 | 0.23443116 |
| 81 | MARK3 | 0.22116252 |
| 82 | PAK1 | 0.21701414 |
| 83 | AURKA | 0.21183132 |
| 84 | GRK5 | 0.19593471 |
| 85 | CSNK1G1 | 0.19367996 |
| 86 | CDK4 | 0.19014007 |
| 87 | CLK1 | 0.17837416 |
| 88 | RAF1 | 0.17488635 |
| 89 | CSNK1E | 0.17367850 |
| 90 | ADRBK1 | 0.16129393 |
| 91 | CAMK1G | 0.16013076 |
| 92 | PRKCH | 0.15012223 |
| 93 | SCYL2 | 0.14738459 |
| 94 | RPS6KA4 | 0.14663040 |
| 95 | MAPK14 | 0.14633084 |
| 96 | MAP3K8 | 0.10744860 |
| 97 | GRK7 | 0.10079069 |
| 98 | MTOR | 0.09632726 |
| 99 | KDR | 0.09534928 |
| 100 | STK3 | 0.09150478 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.95683493 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 4.06809603 |
| 3 | Homologous recombination_Homo sapiens_hsa03440 | 3.68245225 |
| 4 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.60900425 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.51485568 |
| 6 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 3.38093713 |
| 7 | Proteasome_Homo sapiens_hsa03050 | 3.27045440 |
| 8 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.86875509 |
| 9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.69133976 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 2.67990372 |
| 11 | Basal transcription factors_Homo sapiens_hsa03022 | 2.44042831 |
| 12 | Spliceosome_Homo sapiens_hsa03040 | 2.40916744 |
| 13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.40503278 |
| 14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.33724418 |
| 15 | Base excision repair_Homo sapiens_hsa03410 | 2.31592375 |
| 16 | Cell cycle_Homo sapiens_hsa04110 | 1.87584226 |
| 17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.68293282 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 1.67505277 |
| 19 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.49672976 |
| 20 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.48289006 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.47416930 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.44569866 |
| 23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.34101222 |
| 24 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.23115151 |
| 25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.22232200 |
| 26 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.18154036 |
| 27 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.17201617 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.11891011 |
| 29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.11180366 |
| 30 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.07682405 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03404288 |
| 32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.01429163 |
| 33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.00572230 |
| 34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.99159534 |
| 35 | Huntingtons disease_Homo sapiens_hsa05016 | 0.98454868 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.97169549 |
| 37 | Protein export_Homo sapiens_hsa03060 | 0.96445495 |
| 38 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.96070412 |
| 39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93030080 |
| 40 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.92794540 |
| 41 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.89767852 |
| 42 | Ribosome_Homo sapiens_hsa03010 | 0.88636084 |
| 43 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.88112738 |
| 44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.86423141 |
| 45 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.86035299 |
| 46 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.85477685 |
| 47 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.85189269 |
| 48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.81590615 |
| 49 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.81370720 |
| 50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.81314195 |
| 51 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.78469911 |
| 52 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.76205049 |
| 53 | Purine metabolism_Homo sapiens_hsa00230 | 0.75648803 |
| 54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72980024 |
| 55 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72044386 |
| 56 | Carbon metabolism_Homo sapiens_hsa01200 | 0.67525709 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65109900 |
| 58 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65049271 |
| 59 | Lysine degradation_Homo sapiens_hsa00310 | 0.60444958 |
| 60 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.60264815 |
| 61 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.59958014 |
| 62 | Parkinsons disease_Homo sapiens_hsa05012 | 0.58474662 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.57109007 |
| 64 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.55713367 |
| 65 | Peroxisome_Homo sapiens_hsa04146 | 0.53307308 |
| 66 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.52474168 |
| 67 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.51190382 |
| 68 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.50962101 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49452012 |
| 70 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.48574483 |
| 71 | Taste transduction_Homo sapiens_hsa04742 | 0.47488751 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.45577315 |
| 73 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.43653613 |
| 74 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.39737704 |
| 75 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.35942951 |
| 76 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.32633954 |
| 77 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.31674929 |
| 78 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.31066130 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30272016 |
| 80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29197311 |
| 81 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.27767333 |
| 82 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.27376621 |
| 83 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.27188441 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.27064048 |
| 85 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.24372308 |
| 86 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.24061847 |
| 87 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.22964112 |
| 88 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.22760464 |
| 89 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.22396479 |
| 90 | Phototransduction_Homo sapiens_hsa04744 | 0.22315240 |
| 91 | Thyroid cancer_Homo sapiens_hsa05216 | 0.20048065 |
| 92 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.18737839 |
| 93 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.18704407 |
| 94 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.17807228 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.17231644 |
| 96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.15164829 |
| 97 | Alzheimers disease_Homo sapiens_hsa05010 | 0.10532103 |
| 98 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.09823772 |
| 99 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.06058939 |
| 100 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.05788319 |

