

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.74829765 |
| 2 | histone-serine phosphorylation (GO:0035404) | 5.14075365 |
| 3 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.11265451 |
| 4 | spliceosomal complex assembly (GO:0000245) | 4.99616456 |
| 5 | sulfation (GO:0051923) | 4.95615771 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 4.83140290 |
| 7 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.81329344 |
| 8 | regulation of gene silencing by miRNA (GO:0060964) | 4.81329344 |
| 9 | regulation of gene silencing by RNA (GO:0060966) | 4.81329344 |
| 10 | regulation of DNA endoreduplication (GO:0032875) | 4.74137806 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 4.68719775 |
| 12 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.68719775 |
| 13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.58580310 |
| 14 | respiratory electron transport chain (GO:0022904) | 4.34680365 |
| 15 | histone H2B ubiquitination (GO:0033523) | 4.33766482 |
| 16 | regulation of phospholipid biosynthetic process (GO:0071071) | 4.29533290 |
| 17 | electron transport chain (GO:0022900) | 4.27790569 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.22181041 |
| 19 | spinal cord motor neuron differentiation (GO:0021522) | 4.08646646 |
| 20 | histone H3-K4 trimethylation (GO:0080182) | 4.08600019 |
| 21 | chromatin remodeling at centromere (GO:0031055) | 4.07825898 |
| 22 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 4.07650994 |
| 23 | termination of RNA polymerase III transcription (GO:0006386) | 4.06949486 |
| 24 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.06949486 |
| 25 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.95265975 |
| 26 | spliceosomal snRNP assembly (GO:0000387) | 3.94462359 |
| 27 | cellular response to ATP (GO:0071318) | 3.92491801 |
| 28 | regulation of glomerulus development (GO:0090192) | 3.86347809 |
| 29 | regulation of cell maturation (GO:1903429) | 3.85607927 |
| 30 | CENP-A containing nucleosome assembly (GO:0034080) | 3.79784408 |
| 31 | regulation of spindle checkpoint (GO:0090231) | 3.78822862 |
| 32 | otic vesicle formation (GO:0030916) | 3.70364849 |
| 33 | N-acetylglucosamine metabolic process (GO:0006044) | 3.67126141 |
| 34 | centrosome localization (GO:0051642) | 3.65301121 |
| 35 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 3.60174758 |
| 36 | behavioral response to nicotine (GO:0035095) | 3.59564484 |
| 37 | interleukin-6-mediated signaling pathway (GO:0070102) | 3.58240997 |
| 38 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 3.58197526 |
| 39 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.52198984 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.50295044 |
| 41 | inner ear receptor cell development (GO:0060119) | 3.47204326 |
| 42 | protein localization to microtubule cytoskeleton (GO:0072698) | 3.43671409 |
| 43 | protein neddylation (GO:0045116) | 3.43509739 |
| 44 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.42361174 |
| 45 | histone exchange (GO:0043486) | 3.40071967 |
| 46 | regulation of cell proliferation involved in kidney development (GO:1901722) | 3.37789316 |
| 47 | dorsal/ventral axis specification (GO:0009950) | 3.37054626 |
| 48 | epithelial cell fate commitment (GO:0072148) | 3.30808301 |
| 49 | cell proliferation in forebrain (GO:0021846) | 3.30805617 |
| 50 | regulation of acrosome reaction (GO:0060046) | 3.27751229 |
| 51 | pre-miRNA processing (GO:0031054) | 3.21180178 |
| 52 | peristalsis (GO:0030432) | 3.20464970 |
| 53 | neuron fate determination (GO:0048664) | 3.19987519 |
| 54 | cytochrome complex assembly (GO:0017004) | 3.11590645 |
| 55 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.10116380 |
| 56 | pseudouridine synthesis (GO:0001522) | 3.10084627 |
| 57 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.04539084 |
| 58 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.04539084 |
| 59 | NADH dehydrogenase complex assembly (GO:0010257) | 3.04539084 |
| 60 | protein complex biogenesis (GO:0070271) | 3.01730945 |
| 61 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.01668614 |
| 62 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.01668614 |
| 63 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.99007975 |
| 64 | ATP biosynthetic process (GO:0006754) | 2.97800584 |
| 65 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.92833280 |
| 66 | ribosomal small subunit biogenesis (GO:0042274) | 2.91286006 |
| 67 | regulation of spindle organization (GO:0090224) | 2.90223094 |
| 68 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.90083897 |
| 69 | viral transcription (GO:0019083) | 2.89428441 |
| 70 | ribosomal small subunit assembly (GO:0000028) | 2.87033756 |
| 71 | regulation of mitochondrial translation (GO:0070129) | 2.86848021 |
| 72 | hydrogen ion transmembrane transport (GO:1902600) | 2.80671315 |
| 73 | positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) | 2.78759580 |
| 74 | positive regulation of cell cycle G2/M phase transition (GO:1902751) | 2.78759580 |
| 75 | negative regulation of cardiac muscle tissue development (GO:0055026) | 2.78374125 |
| 76 | regulation of helicase activity (GO:0051095) | 2.78140197 |
| 77 | protein localization to cytoskeleton (GO:0044380) | 2.77473650 |
| 78 | DNA replication-independent nucleosome organization (GO:0034724) | 2.77384073 |
| 79 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.77384073 |
| 80 | opsonization (GO:0008228) | 2.76462088 |
| 81 | termination of RNA polymerase II transcription (GO:0006369) | 2.75627407 |
| 82 | artery development (GO:0060840) | 2.74510125 |
| 83 | regulation of chromatin binding (GO:0035561) | 2.73887827 |
| 84 | lateral sprouting from an epithelium (GO:0060601) | 2.73443699 |
| 85 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.73023329 |
| 86 | DNA-templated transcription, termination (GO:0006353) | 2.72493299 |
| 87 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.71977097 |
| 88 | protein targeting to mitochondrion (GO:0006626) | 2.71581926 |
| 89 | response to UV-C (GO:0010225) | 2.70475351 |
| 90 | negative regulation of telomerase activity (GO:0051974) | 2.70447415 |
| 91 | female gonad development (GO:0008585) | 2.69619334 |
| 92 | regulation of G2/M transition of mitotic cell cycle (GO:0010389) | 2.68376554 |
| 93 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.66144100 |
| 94 | proteasome assembly (GO:0043248) | 2.65714397 |
| 95 | rRNA modification (GO:0000154) | 2.64348003 |
| 96 | presynaptic membrane assembly (GO:0097105) | 2.62519850 |
| 97 | positive regulation of metanephros development (GO:0072216) | 2.61773579 |
| 98 | translational termination (GO:0006415) | 2.61025047 |
| 99 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.60804475 |
| 100 | pituitary gland development (GO:0021983) | 2.60004188 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 4.18529818 |
| 2 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.07103951 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.94116596 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.53383022 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.50535080 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.45460357 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.98951264 |
| 8 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 2.65915147 |
| 9 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.65736911 |
| 10 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.65188196 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.61103762 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.49404155 |
| 13 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.41773119 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.41676545 |
| 15 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 2.34922891 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.34225178 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.09465624 |
| 18 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.07604161 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 2.04950141 |
| 20 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.01142327 |
| 21 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.94577949 |
| 22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.93008196 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.91748539 |
| 24 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.91359611 |
| 25 | FUS_26573619_Chip-Seq_HEK293_Human | 1.90788985 |
| 26 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.87107213 |
| 27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.82358293 |
| 28 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.79935968 |
| 29 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.79228484 |
| 30 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.78060703 |
| 31 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.77119619 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.74712801 |
| 33 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.74160364 |
| 34 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.72464280 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.71162953 |
| 36 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.70975226 |
| 37 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.70859257 |
| 38 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.55582601 |
| 39 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.55582601 |
| 40 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.55582601 |
| 41 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.52647123 |
| 42 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.49766191 |
| 43 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.47464797 |
| 44 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.46133159 |
| 45 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.39953991 |
| 46 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.39128844 |
| 47 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.35097488 |
| 48 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.33078076 |
| 49 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.31629730 |
| 50 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.31375480 |
| 51 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.30053578 |
| 52 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28987339 |
| 53 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.27284658 |
| 54 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.26502041 |
| 55 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.25269037 |
| 56 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.25197830 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.24378359 |
| 58 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.21198618 |
| 59 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.17572137 |
| 60 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.15564095 |
| 61 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14954449 |
| 62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.13967369 |
| 63 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.13806152 |
| 64 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13557076 |
| 65 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.09115245 |
| 66 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.08253042 |
| 67 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.06994219 |
| 68 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.06366022 |
| 69 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.05648673 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05564577 |
| 71 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.03942902 |
| 72 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.03942902 |
| 73 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.02452004 |
| 74 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.02327741 |
| 75 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.01796682 |
| 76 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.00298919 |
| 77 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.99342887 |
| 78 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.98255732 |
| 79 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.97239130 |
| 80 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.95980886 |
| 81 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.94006204 |
| 82 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.92983754 |
| 83 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.91606359 |
| 84 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.91145646 |
| 85 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.90964582 |
| 86 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.90487062 |
| 87 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.89153049 |
| 88 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88836099 |
| 89 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.88610622 |
| 90 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.87589381 |
| 91 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.86038773 |
| 92 | NANOG_18692474_ChIP-Seq_MESCs_Mouse | 0.85730870 |
| 93 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.85422842 |
| 94 | SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.83582637 |
| 95 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.83477258 |
| 96 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.81475420 |
| 97 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.79462532 |
| 98 | JUN_21703547_ChIP-Seq_K562_Human | 0.78953598 |
| 99 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.78390822 |
| 100 | TCF3_18347094_ChIP-ChIP_MESCs_Mouse | 0.78215345 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.23000529 |
| 2 | MP0003693_abnormal_embryo_hatching | 4.16295487 |
| 3 | MP0003941_abnormal_skin_development | 4.02563845 |
| 4 | MP0009379_abnormal_foot_pigmentation | 3.53372688 |
| 5 | MP0008877_abnormal_DNA_methylation | 3.08826555 |
| 6 | MP0008057_abnormal_DNA_replication | 2.97942715 |
| 7 | MP0004134_abnormal_chest_morphology | 2.66856047 |
| 8 | MP0003195_calcinosis | 2.39657988 |
| 9 | MP0003787_abnormal_imprinting | 2.30495777 |
| 10 | MP0000049_abnormal_middle_ear | 2.20134057 |
| 11 | MP0002277_abnormal_respiratory_mucosa | 2.20071472 |
| 12 | MP0002735_abnormal_chemical_nociception | 2.13428573 |
| 13 | MP0001485_abnormal_pinna_reflex | 2.10780518 |
| 14 | MP0009780_abnormal_chondrocyte_physiolo | 2.04968544 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 2.01243296 |
| 16 | MP0010094_abnormal_chromosome_stability | 1.97912778 |
| 17 | MP0001188_hyperpigmentation | 1.83099709 |
| 18 | MP0003111_abnormal_nucleus_morphology | 1.74620152 |
| 19 | MP0003122_maternal_imprinting | 1.69857872 |
| 20 | MP0003136_yellow_coat_color | 1.69524601 |
| 21 | MP0009250_abnormal_appendicular_skeleto | 1.69397869 |
| 22 | MP0003121_genomic_imprinting | 1.64395728 |
| 23 | MP0004885_abnormal_endolymph | 1.56883599 |
| 24 | MP0001293_anophthalmia | 1.54631430 |
| 25 | MP0004133_heterotaxia | 1.53742464 |
| 26 | MP0000631_abnormal_neuroendocrine_gland | 1.53523778 |
| 27 | MP0003077_abnormal_cell_cycle | 1.52597178 |
| 28 | MP0001968_abnormal_touch/_nociception | 1.49259460 |
| 29 | MP0003938_abnormal_ear_development | 1.42049246 |
| 30 | MP0002160_abnormal_reproductive_system | 1.40961537 |
| 31 | MP0002089_abnormal_postnatal_growth/wei | 1.40533541 |
| 32 | MP0002734_abnormal_mechanical_nocicepti | 1.38101238 |
| 33 | MP0004142_abnormal_muscle_tone | 1.37841225 |
| 34 | MP0008007_abnormal_cellular_replicative | 1.36372161 |
| 35 | MP0000428_abnormal_craniofacial_morphol | 1.36200661 |
| 36 | MP0009053_abnormal_anal_canal | 1.35858448 |
| 37 | MP0003937_abnormal_limbs/digits/tail_de | 1.33622294 |
| 38 | MP0003718_maternal_effect | 1.32633637 |
| 39 | MP0003638_abnormal_response/metabolism_ | 1.32630556 |
| 40 | MP0004957_abnormal_blastocyst_morpholog | 1.31923558 |
| 41 | MP0002111_abnormal_tail_morphology | 1.28467935 |
| 42 | MP0008872_abnormal_physiological_respon | 1.28203515 |
| 43 | MP0002254_reproductive_system_inflammat | 1.27457371 |
| 44 | MP0001177_atelectasis | 1.22708021 |
| 45 | MP0005551_abnormal_eye_electrophysiolog | 1.21955048 |
| 46 | MP0000750_abnormal_muscle_regeneration | 1.21556160 |
| 47 | MP0002249_abnormal_larynx_morphology | 1.20108754 |
| 48 | MP0004145_abnormal_muscle_electrophysio | 1.15265309 |
| 49 | MP0006276_abnormal_autonomic_nervous | 1.12683781 |
| 50 | MP0003755_abnormal_palate_morphology | 1.12472945 |
| 51 | MP0009672_abnormal_birth_weight | 1.09557016 |
| 52 | MP0005389_reproductive_system_phenotype | 1.09432968 |
| 53 | MP0001286_abnormal_eye_development | 1.09391489 |
| 54 | MP0002751_abnormal_autonomic_nervous | 1.07068077 |
| 55 | MP0003890_abnormal_embryonic-extraembry | 1.06263343 |
| 56 | MP0003183_abnormal_peptide_metabolism | 1.05453868 |
| 57 | MP0002733_abnormal_thermal_nociception | 1.01534543 |
| 58 | MP0002736_abnormal_nociception_after | 1.01243822 |
| 59 | MP0005084_abnormal_gallbladder_morpholo | 1.00864491 |
| 60 | MP0001919_abnormal_reproductive_system | 1.00379065 |
| 61 | MP0003878_abnormal_ear_physiology | 0.96174064 |
| 62 | MP0005377_hearing/vestibular/ear_phenot | 0.96174064 |
| 63 | MP0000678_abnormal_parathyroid_gland | 0.95610690 |
| 64 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94861140 |
| 65 | MP0002138_abnormal_hepatobiliary_system | 0.92960304 |
| 66 | MP0009046_muscle_twitch | 0.92637225 |
| 67 | MP0000733_abnormal_muscle_development | 0.90420405 |
| 68 | MP0001145_abnormal_male_reproductive | 0.89655725 |
| 69 | MP0002272_abnormal_nervous_system | 0.89610330 |
| 70 | MP0004270_analgesia | 0.89477025 |
| 71 | MP0003942_abnormal_urinary_system | 0.89218041 |
| 72 | MP0005360_urolithiasis | 0.89078065 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.86545361 |
| 74 | MP0001970_abnormal_pain_threshold | 0.85522690 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.85343242 |
| 76 | MP0002233_abnormal_nose_morphology | 0.82892563 |
| 77 | MP0000026_abnormal_inner_ear | 0.82579099 |
| 78 | MP0002116_abnormal_craniofacial_bone | 0.82538635 |
| 79 | MP0002085_abnormal_embryonic_tissue | 0.82317346 |
| 80 | MP0003137_abnormal_impulse_conducting | 0.82118640 |
| 81 | MP0000350_abnormal_cell_proliferation | 0.81697550 |
| 82 | MP0003880_abnormal_central_pattern | 0.80706649 |
| 83 | MP0003119_abnormal_digestive_system | 0.80390985 |
| 84 | MP0005195_abnormal_posterior_eye | 0.79346464 |
| 85 | MP0003861_abnormal_nervous_system | 0.79193794 |
| 86 | MP0001697_abnormal_embryo_size | 0.76764648 |
| 87 | MP0009703_decreased_birth_body | 0.76718327 |
| 88 | MP0008932_abnormal_embryonic_tissue | 0.74864196 |
| 89 | MP0000653_abnormal_sex_gland | 0.74300368 |
| 90 | MP0001963_abnormal_hearing_physiology | 0.73631866 |
| 91 | MP0000762_abnormal_tongue_morphology | 0.73513727 |
| 92 | MP0003011_delayed_dark_adaptation | 0.73090119 |
| 93 | MP0002210_abnormal_sex_determination | 0.72786838 |
| 94 | MP0002102_abnormal_ear_morphology | 0.69438720 |
| 95 | MP0006036_abnormal_mitochondrial_physio | 0.68310213 |
| 96 | MP0001542_abnormal_bone_strength | 0.68181475 |
| 97 | MP0002184_abnormal_innervation | 0.68071808 |
| 98 | MP0003936_abnormal_reproductive_system | 0.66927708 |
| 99 | MP0004130_abnormal_muscle_cell | 0.66926284 |
| 100 | MP0005253_abnormal_eye_physiology | 0.66858191 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Confusion (HP:0001289) | 5.05640590 |
| 2 | Septo-optic dysplasia (HP:0100842) | 4.78760947 |
| 3 | Pendular nystagmus (HP:0012043) | 4.62760678 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.96668941 |
| 5 | Methylmalonic acidemia (HP:0002912) | 3.59427970 |
| 6 | Abnormality of homocysteine metabolism (HP:0010919) | 3.55445403 |
| 7 | Homocystinuria (HP:0002156) | 3.55445403 |
| 8 | Volvulus (HP:0002580) | 3.55199407 |
| 9 | Abolished electroretinogram (ERG) (HP:0000550) | 3.52084824 |
| 10 | Congenital, generalized hypertrichosis (HP:0004540) | 3.51595681 |
| 11 | Abnormality of methionine metabolism (HP:0010901) | 3.48614426 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.29843808 |
| 13 | Methylmalonic aciduria (HP:0012120) | 3.28253237 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.20912546 |
| 15 | Severe visual impairment (HP:0001141) | 3.17481105 |
| 16 | Oral leukoplakia (HP:0002745) | 3.15999148 |
| 17 | Acute encephalopathy (HP:0006846) | 3.07720568 |
| 18 | Increased hepatocellular lipid droplets (HP:0006565) | 2.99537261 |
| 19 | Mitochondrial inheritance (HP:0001427) | 2.99314659 |
| 20 | Decreased central vision (HP:0007663) | 2.96301996 |
| 21 | Abnormal number of incisors (HP:0011064) | 2.93439812 |
| 22 | Dry hair (HP:0011359) | 2.91754693 |
| 23 | Truncal obesity (HP:0001956) | 2.88402226 |
| 24 | Optic nerve hypoplasia (HP:0000609) | 2.84601023 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.84191045 |
| 26 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.80666521 |
| 27 | Porencephaly (HP:0002132) | 2.76037510 |
| 28 | Macrocytic anemia (HP:0001972) | 2.75488533 |
| 29 | Abnormal number of erythroid precursors (HP:0012131) | 2.75441459 |
| 30 | Genetic anticipation (HP:0003743) | 2.74370824 |
| 31 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.69717600 |
| 32 | True hermaphroditism (HP:0010459) | 2.66622381 |
| 33 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.65438622 |
| 34 | Lipid accumulation in hepatocytes (HP:0006561) | 2.62991992 |
| 35 | Cleft eyelid (HP:0000625) | 2.61605267 |
| 36 | Pancreatic cysts (HP:0001737) | 2.57316781 |
| 37 | Woolly hair (HP:0002224) | 2.55880389 |
| 38 | Cerebral edema (HP:0002181) | 2.53942358 |
| 39 | Absent septum pellucidum (HP:0001331) | 2.53157803 |
| 40 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.47205994 |
| 41 | Short 1st metacarpal (HP:0010034) | 2.47205994 |
| 42 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.44417151 |
| 43 | Megaloblastic anemia (HP:0001889) | 2.42558618 |
| 44 | 3-Methylglutaconic aciduria (HP:0003535) | 2.42522891 |
| 45 | Optic disc pallor (HP:0000543) | 2.39310067 |
| 46 | Increased CSF lactate (HP:0002490) | 2.37334286 |
| 47 | Renal Fanconi syndrome (HP:0001994) | 2.36336593 |
| 48 | Progressive cerebellar ataxia (HP:0002073) | 2.33568385 |
| 49 | Agitation (HP:0000713) | 2.31306951 |
| 50 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.28302608 |
| 51 | Rib fusion (HP:0000902) | 2.26994608 |
| 52 | Facial cleft (HP:0002006) | 2.22603525 |
| 53 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.21930782 |
| 54 | Constricted visual fields (HP:0001133) | 2.21781341 |
| 55 | Abnormality of the septum pellucidum (HP:0007375) | 2.20388085 |
| 56 | Hypoglycemic seizures (HP:0002173) | 2.20184243 |
| 57 | Abnormality of the nasolacrimal system (HP:0000614) | 2.18982012 |
| 58 | Abnormality of the 1st metacarpal (HP:0010009) | 2.17985126 |
| 59 | Maternal diabetes (HP:0009800) | 2.17656119 |
| 60 | Mesomelia (HP:0003027) | 2.15372426 |
| 61 | Abnormality of the lacrimal duct (HP:0011481) | 2.11506424 |
| 62 | Furrowed tongue (HP:0000221) | 2.07351368 |
| 63 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.06256571 |
| 64 | Abnormality of proline metabolism (HP:0010907) | 2.06088434 |
| 65 | Hydroxyprolinuria (HP:0003080) | 2.06088434 |
| 66 | Nasolacrimal duct obstruction (HP:0000579) | 2.04460370 |
| 67 | Bilateral microphthalmos (HP:0007633) | 2.04231572 |
| 68 | Increased corneal curvature (HP:0100692) | 2.03716384 |
| 69 | Keratoconus (HP:0000563) | 2.03716384 |
| 70 | Abnormal lung lobation (HP:0002101) | 2.03172193 |
| 71 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.01953951 |
| 72 | Abnormality of the axillary hair (HP:0100134) | 2.01778322 |
| 73 | Abnormality of secondary sexual hair (HP:0009888) | 2.01778322 |
| 74 | Abnormality of the nasal septum (HP:0000419) | 2.00826504 |
| 75 | Pallor (HP:0000980) | 1.98536514 |
| 76 | Hypoglycemic coma (HP:0001325) | 1.97232170 |
| 77 | Radial bowing (HP:0002986) | 1.94597521 |
| 78 | Breast aplasia (HP:0100783) | 1.94289850 |
| 79 | Reticulocytopenia (HP:0001896) | 1.92820435 |
| 80 | Intrahepatic cholestasis (HP:0001406) | 1.92444574 |
| 81 | Male pseudohermaphroditism (HP:0000037) | 1.90552577 |
| 82 | Goiter (HP:0000853) | 1.90383610 |
| 83 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.89185540 |
| 84 | Short hallux (HP:0010109) | 1.87739414 |
| 85 | Abnormality of vitamin B metabolism (HP:0004340) | 1.87717235 |
| 86 | Conjunctival hamartoma (HP:0100780) | 1.87015456 |
| 87 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.86761247 |
| 88 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.84996084 |
| 89 | Hyperglycinuria (HP:0003108) | 1.84766354 |
| 90 | Sclerocornea (HP:0000647) | 1.83436460 |
| 91 | Hepatocellular necrosis (HP:0001404) | 1.82033116 |
| 92 | Abnormality of vitamin metabolism (HP:0100508) | 1.80906603 |
| 93 | Leukodystrophy (HP:0002415) | 1.79621188 |
| 94 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.78859980 |
| 95 | Abnormality of cochlea (HP:0000375) | 1.78751000 |
| 96 | Hypoplastic ischia (HP:0003175) | 1.78375737 |
| 97 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.77697498 |
| 98 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.77165230 |
| 99 | Aplastic anemia (HP:0001915) | 1.76722622 |
| 100 | Proximal placement of thumb (HP:0009623) | 1.75487058 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAF1 | 5.69802060 |
| 2 | VRK2 | 4.51348934 |
| 3 | MARK1 | 3.39909981 |
| 4 | CDC7 | 2.52992988 |
| 5 | CASK | 2.46738626 |
| 6 | TNIK | 2.34231842 |
| 7 | NME1 | 2.21670189 |
| 8 | BUB1 | 2.07162325 |
| 9 | GRK1 | 2.06409133 |
| 10 | PBK | 2.06125714 |
| 11 | MAP3K9 | 10.5154782 |
| 12 | PNCK | 1.91048412 |
| 13 | STK16 | 1.73532431 |
| 14 | MST4 | 1.58887885 |
| 15 | VRK1 | 1.57972752 |
| 16 | PIK3CG | 1.49148674 |
| 17 | ADRBK2 | 1.37519204 |
| 18 | DYRK2 | 1.31737813 |
| 19 | NUAK1 | 1.29003153 |
| 20 | SRPK1 | 1.25052406 |
| 21 | AURKA | 0.96338051 |
| 22 | DDR2 | 0.93568346 |
| 23 | FES | 0.90361298 |
| 24 | CHEK2 | 0.88015512 |
| 25 | BMPR1B | 0.85248448 |
| 26 | AURKB | 0.84989300 |
| 27 | CSNK1G1 | 0.83747885 |
| 28 | MATK | 0.81200931 |
| 29 | PLK3 | 0.80777805 |
| 30 | PLK1 | 0.80509297 |
| 31 | TYRO3 | 0.79451321 |
| 32 | NTRK2 | 0.77822582 |
| 33 | MKNK2 | 0.76927951 |
| 34 | DYRK3 | 0.75170834 |
| 35 | PRKD2 | 0.70861287 |
| 36 | PINK1 | 0.63305610 |
| 37 | MKNK1 | 0.60377612 |
| 38 | NLK | 0.60244494 |
| 39 | PAK1 | 0.59172050 |
| 40 | SMG1 | 0.58559380 |
| 41 | WNK3 | 0.55312747 |
| 42 | TLK1 | 0.53851120 |
| 43 | CSNK1E | 0.53562467 |
| 44 | ARAF | 0.53287284 |
| 45 | BRSK2 | 0.52134186 |
| 46 | BRAF | 0.51241667 |
| 47 | CDK7 | 0.50287371 |
| 48 | CDK9 | 0.49984412 |
| 49 | ACVR1B | 0.49056180 |
| 50 | GRK6 | 0.48799418 |
| 51 | TTK | 0.48507257 |
| 52 | PRKCG | 0.47803907 |
| 53 | ZAK | 0.47672370 |
| 54 | NME2 | 0.46870399 |
| 55 | FER | 0.46408867 |
| 56 | CSNK1G3 | 0.45548242 |
| 57 | NEK9 | 0.45321166 |
| 58 | CSNK1G2 | 0.44551750 |
| 59 | CAMK1G | 0.44258145 |
| 60 | CSNK2A2 | 0.43705080 |
| 61 | SGK2 | 0.42926986 |
| 62 | MAPKAPK5 | 0.40992438 |
| 63 | PLK4 | 0.40794447 |
| 64 | CHEK1 | 0.40729775 |
| 65 | MAPK4 | 0.39569679 |
| 66 | INSRR | 0.37830281 |
| 67 | CAMK1 | 0.37645048 |
| 68 | CSNK1A1 | 0.35493941 |
| 69 | MAP3K10 | 0.34269403 |
| 70 | CSNK2A1 | 0.32993738 |
| 71 | ATM | 0.32779152 |
| 72 | SGK223 | 0.32095547 |
| 73 | SGK494 | 0.32095547 |
| 74 | GRK5 | 0.31747670 |
| 75 | CSNK1A1L | 0.29978717 |
| 76 | PRKDC | 0.28617337 |
| 77 | DAPK1 | 0.27574695 |
| 78 | NEK2 | 0.26891840 |
| 79 | ATR | 0.25829440 |
| 80 | MAP3K13 | 0.25570435 |
| 81 | OXSR1 | 0.24877855 |
| 82 | PRKCH | 0.23966815 |
| 83 | FGR | 0.23410018 |
| 84 | EIF2AK1 | 0.23346459 |
| 85 | NEK1 | 0.22644990 |
| 86 | CHUK | 0.22522007 |
| 87 | TAOK2 | 0.22199051 |
| 88 | TEC | 0.21216086 |
| 89 | CDK2 | 0.20892579 |
| 90 | PRKG1 | 0.20869212 |
| 91 | RPS6KB1 | 0.20618365 |
| 92 | GSK3B | 0.18803138 |
| 93 | CDK1 | 0.18341233 |
| 94 | PRKACA | 0.17609252 |
| 95 | EIF2AK2 | 0.16972443 |
| 96 | CSNK1D | 0.15994312 |
| 97 | PRKG2 | 0.15955045 |
| 98 | DAPK3 | 0.15887265 |
| 99 | RPS6KA3 | 0.15448476 |
| 100 | STK24 | 0.15276975 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.20530714 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.89144661 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.51144314 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 3.35762420 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 3.24102200 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.79788883 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.72952788 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.71907596 |
| 9 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.65738429 |
| 10 | Basal transcription factors_Homo sapiens_hsa03022 | 2.62527838 |
| 11 | Spliceosome_Homo sapiens_hsa03040 | 2.62453781 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.59079442 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 2.57031311 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.47005364 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.41421662 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.25437410 |
| 17 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.20430465 |
| 18 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.07777106 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.90220470 |
| 20 | Mismatch repair_Homo sapiens_hsa03430 | 1.85656664 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.77343944 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.63081308 |
| 23 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.35883554 |
| 24 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.30209356 |
| 25 | Nicotine addiction_Homo sapiens_hsa05033 | 1.28057248 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.24536290 |
| 27 | Melanoma_Homo sapiens_hsa05218 | 1.23530651 |
| 28 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.19595307 |
| 29 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.14241538 |
| 30 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.11057242 |
| 31 | Taste transduction_Homo sapiens_hsa04742 | 1.08891050 |
| 32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.07997537 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.06259770 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.04273875 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02976892 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.02150797 |
| 37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.99983004 |
| 38 | Phototransduction_Homo sapiens_hsa04744 | 0.99802278 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 0.99269816 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.98032318 |
| 41 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.96218915 |
| 42 | Cell cycle_Homo sapiens_hsa04110 | 0.95745223 |
| 43 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.94350453 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.93498219 |
| 45 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.91641127 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.86366727 |
| 47 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.84954425 |
| 48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.83196951 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.79650373 |
| 50 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.78433333 |
| 51 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.70183774 |
| 52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.67982024 |
| 53 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.66002292 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64181007 |
| 55 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.63824381 |
| 56 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.63429936 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.61919572 |
| 58 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.60609203 |
| 59 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.57721373 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56976068 |
| 61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.54306241 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.54085106 |
| 63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52459335 |
| 64 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48144248 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43948765 |
| 66 | Morphine addiction_Homo sapiens_hsa05032 | 0.42933682 |
| 67 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.40786479 |
| 68 | Thyroid cancer_Homo sapiens_hsa05216 | 0.40532065 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.37879835 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.36630134 |
| 71 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35356632 |
| 72 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.32547478 |
| 73 | Prostate cancer_Homo sapiens_hsa05215 | 0.31488629 |
| 74 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.31307821 |
| 75 | Olfactory transduction_Homo sapiens_hsa04740 | 0.30000840 |
| 76 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.29910656 |
| 77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.29695973 |
| 78 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.29052455 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27232218 |
| 80 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.27185672 |
| 81 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.25130505 |
| 82 | GABAergic synapse_Homo sapiens_hsa04727 | 0.25095892 |
| 83 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.24626235 |
| 84 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.23937964 |
| 85 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.22548703 |
| 86 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.21791132 |
| 87 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.21322513 |
| 88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.20639308 |
| 89 | Melanogenesis_Homo sapiens_hsa04916 | 0.20371461 |
| 90 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.19909556 |
| 91 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.19874026 |
| 92 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.19428278 |
| 93 | Tight junction_Homo sapiens_hsa04530 | 0.19247986 |
| 94 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.17713824 |
| 95 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.17240085 |
| 96 | Histidine metabolism_Homo sapiens_hsa00340 | 0.15795631 |
| 97 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.15718039 |
| 98 | Gap junction_Homo sapiens_hsa04540 | 0.15297033 |
| 99 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.15150868 |
| 100 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.14686280 |

