DAB2IP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)4.02856818
2sodium ion export (GO:0071436)3.98474642
3cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.96765260
4synaptic vesicle maturation (GO:0016188)3.93118886
5cytoskeletal anchoring at plasma membrane (GO:0007016)3.89934932
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.81921361
7regulation of short-term neuronal synaptic plasticity (GO:0048172)3.81202763
8cell communication by electrical coupling (GO:0010644)3.80265810
9plasma membrane repair (GO:0001778)3.79719249
10vocalization behavior (GO:0071625)3.66849700
11hemidesmosome assembly (GO:0031581)3.60300426
12regulation of synapse structural plasticity (GO:0051823)3.43935698
13synaptic vesicle docking involved in exocytosis (GO:0016081)3.43290423
14cellular potassium ion homeostasis (GO:0030007)3.41445748
15* layer formation in cerebral cortex (GO:0021819)3.38752488
16desmosome organization (GO:0002934)3.37867315
17establishment of nucleus localization (GO:0040023)3.35970335
18cell communication involved in cardiac conduction (GO:0086065)3.35288690
19positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.29463750
20dendritic spine morphogenesis (GO:0060997)3.25744309
21activation of protein kinase A activity (GO:0034199)3.16383264
22planar cell polarity pathway involved in neural tube closure (GO:0090179)3.14653627
23regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.03463188
24regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.02666759
25synaptic vesicle exocytosis (GO:0016079)2.98299184
26glutamate secretion (GO:0014047)2.97978570
27cell migration in hindbrain (GO:0021535)2.95581678
28semaphorin-plexin signaling pathway (GO:0071526)2.93029790
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.90957730
30cell-substrate junction assembly (GO:0007044)2.88014748
31cardiac myofibril assembly (GO:0055003)2.86529331
32neuromuscular process controlling balance (GO:0050885)2.86474553
33positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.86109352
34regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.84812319
35negative regulation of potassium ion transmembrane transport (GO:1901380)2.84482431
36regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.83894516
37regulation of synaptic vesicle exocytosis (GO:2000300)2.83004265
38negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.81922699
39cerebellar Purkinje cell differentiation (GO:0021702)2.80098769
40neuronal ion channel clustering (GO:0045161)2.75540496
41regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.75528131
42regulation of glutamate receptor signaling pathway (GO:1900449)2.75240119
43negative regulation of cytosolic calcium ion concentration (GO:0051481)2.73258654
44exploration behavior (GO:0035640)2.72918774
45potassium ion import (GO:0010107)2.72700558
46regulation of membrane repolarization (GO:0060306)2.71867648
47cell-substrate adherens junction assembly (GO:0007045)2.70127936
48focal adhesion assembly (GO:0048041)2.70127936
49* positive regulation of synapse maturation (GO:0090129)2.69784761
50membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.69735146
51cerebellar granule cell differentiation (GO:0021707)2.67758528
52axonal fasciculation (GO:0007413)2.63471173
53dendrite morphogenesis (GO:0048813)2.61784135
54regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.61661618
55neurotransmitter secretion (GO:0007269)2.60769046
56proline transport (GO:0015824)2.57424241
57membrane repolarization (GO:0086009)2.57271315
58cell-cell junction maintenance (GO:0045217)2.56979912
59regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.55821465
60establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.55634924
61potassium ion homeostasis (GO:0055075)2.54788894
62peripheral nervous system axon ensheathment (GO:0032292)2.53953865
63myelination in peripheral nervous system (GO:0022011)2.53953865
64cellular sodium ion homeostasis (GO:0006883)2.51524773
65cardiac conduction (GO:0061337)2.50536911
66adherens junction assembly (GO:0034333)2.50347783
67amino acid import (GO:0043090)2.50316417
68cardiac muscle contraction (GO:0060048)2.50197323
69regulation of long-term neuronal synaptic plasticity (GO:0048169)2.49719959
70regulation of neuronal synaptic plasticity (GO:0048168)2.48618097
71membrane repolarization during action potential (GO:0086011)2.48162294
72ventricular cardiac muscle cell action potential (GO:0086005)2.48097431
73neuromuscular junction development (GO:0007528)2.47261416
74regulation of heart rate by cardiac conduction (GO:0086091)2.46158650
75neurotransmitter-gated ion channel clustering (GO:0072578)2.45606374
76regulation of dendritic spine morphogenesis (GO:0061001)2.45480481
77endothelial cell chemotaxis (GO:0035767)2.44922223
78positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.44552548
79atrioventricular valve morphogenesis (GO:0003181)2.43030773
80cell volume homeostasis (GO:0006884)2.42741668
81dendritic spine organization (GO:0097061)2.42612246
82growth hormone secretion (GO:0030252)2.41904520
83membrane depolarization during action potential (GO:0086010)2.41875081
84stress fiber assembly (GO:0043149)2.40709188
85positive regulation of potassium ion transmembrane transport (GO:1901381)2.40457076
86protein localization to synapse (GO:0035418)2.39706477
87innervation (GO:0060384)2.38013824
88regulation of ARF protein signal transduction (GO:0032012)2.37727959
89camera-type eye morphogenesis (GO:0048593)2.37137594
90ionotropic glutamate receptor signaling pathway (GO:0035235)2.36594965
91protein targeting to plasma membrane (GO:0072661)2.36412579
92regulation of synaptic vesicle transport (GO:1902803)2.36017268
93insulin-like growth factor receptor signaling pathway (GO:0048009)2.35982247
94regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.35637516
95auditory behavior (GO:0031223)2.35123465
96response to pheromone (GO:0019236)2.34811286
97neuron recognition (GO:0008038)2.34402992
98protein retention in ER lumen (GO:0006621)2.33920108
99postsynaptic membrane organization (GO:0001941)2.32509474
100positive regulation of dendritic spine development (GO:0060999)2.31803221
101neuronal action potential propagation (GO:0019227)2.30645446
102bundle of His cell to Purkinje myocyte communication (GO:0086069)2.30068382
103cardiac muscle cell action potential involved in contraction (GO:0086002)2.29212294
104cerebellar Purkinje cell layer development (GO:0021680)2.29120685
105glutamate receptor signaling pathway (GO:0007215)2.28311454
106epithelial cell-cell adhesion (GO:0090136)2.27555290
107cardiac muscle cell action potential (GO:0086001)2.26959647
108G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.26568069
109long-term memory (GO:0007616)2.26138485
110basement membrane organization (GO:0071711)2.24798091
111regulation of cholesterol homeostasis (GO:2000188)2.23758369
112mating behavior (GO:0007617)2.23467056
113cell junction maintenance (GO:0034331)2.22728922
114regulation of calcium ion transmembrane transporter activity (GO:1901019)2.21902991
115regulation of calcium ion transmembrane transport (GO:1903169)2.21902991
116positive regulation of axon extension (GO:0045773)2.21598727
117synaptic transmission, glutamatergic (GO:0035249)2.20992860
118axon extension (GO:0048675)2.20910022
119polarized epithelial cell differentiation (GO:0030859)2.20546242
120hippo signaling (GO:0035329)2.20441653
121sarcomere organization (GO:0045214)2.20406304
122regulation of potassium ion transmembrane transporter activity (GO:1901016)2.20267098
123regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.20024579
124glycine transport (GO:0015816)2.19884846
125regulation of potassium ion transmembrane transport (GO:1901379)2.19879123
126apical protein localization (GO:0045176)2.19616489
127dopamine receptor signaling pathway (GO:0007212)2.19478973
128Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.19384324
129gonadal mesoderm development (GO:0007506)2.19375571
130glial cell proliferation (GO:0014009)2.18424931
131maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.17291986
132G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.17163772
133* regulation of synapse maturation (GO:0090128)2.15358113
134axon ensheathment in central nervous system (GO:0032291)2.15246086
135central nervous system myelination (GO:0022010)2.15246086
136L-amino acid import (GO:0043092)2.13118516
137peptidyl-tyrosine autophosphorylation (GO:0038083)2.12922789
138synaptic vesicle endocytosis (GO:0048488)2.12608357
139cellular response to monoamine stimulus (GO:0071868)2.12479862
140cellular response to catecholamine stimulus (GO:0071870)2.12479862
141regulation of synaptic plasticity (GO:0048167)2.08198176
142regulation of early endosome to late endosome transport (GO:2000641)2.06781730
143protein localization to endosome (GO:0036010)2.06020891
144regulation of establishment of planar polarity (GO:0090175)2.05362193
145actin filament depolymerization (GO:0030042)2.03987361
146adherens junction organization (GO:0034332)2.03607593
147developmental cell growth (GO:0048588)2.03029138
148actin filament capping (GO:0051693)2.02512394
149receptor recycling (GO:0001881)2.01674044
150barbed-end actin filament capping (GO:0051016)2.01672161
151regulation of axon extension involved in axon guidance (GO:0048841)2.01106568

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.56874642
2EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.58699824
3EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40990623
4RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40990623
5DROSHA_22980978_ChIP-Seq_HELA_Human2.38867839
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.36652658
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.13004193
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.12559513
9ZFP281_18757296_ChIP-ChIP_E14_Mouse2.09807341
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.05852923
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.04051070
12KDM2B_26808549_Chip-Seq_K562_Human1.99711809
13SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.98279732
14MTF2_20144788_ChIP-Seq_MESCs_Mouse1.97142114
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.96355952
16RARB_27405468_Chip-Seq_BRAIN_Mouse1.92453017
17WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.90306262
18EZH2_27304074_Chip-Seq_ESCs_Mouse1.86512213
19* RNF2_27304074_Chip-Seq_ESCs_Mouse1.85305462
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.84558373
21STAT6_21828071_ChIP-Seq_BEAS2B_Human1.84539428
22EZH2_27294783_Chip-Seq_ESCs_Mouse1.84491042
23PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.82200382
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.81308794
25* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.81030998
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.79971449
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.79672178
28SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.79509362
29* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.76209310
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.74890988
31SUZ12_27294783_Chip-Seq_ESCs_Mouse1.71515877
32ZFP281_27345836_Chip-Seq_ESCs_Mouse1.69759715
33ZNF263_19887448_ChIP-Seq_K562_Human1.66961364
34TRIM28_21343339_ChIP-Seq_HEK293_Human1.61269832
35* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.60577371
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.60151512
37ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.59050337
38* MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.55213026
39EP300_21415370_ChIP-Seq_HL-1_Mouse1.53168328
40ESR2_21235772_ChIP-Seq_MCF-7_Human1.52556315
41ESR1_21235772_ChIP-Seq_MCF-7_Human1.52281284
42* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.50527549
43TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.50200286
44DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.48750505
45WT1_25993318_ChIP-Seq_PODOCYTE_Human1.45240067
46IKZF1_21737484_ChIP-ChIP_HCT116_Human1.42915439
47REST_21632747_ChIP-Seq_MESCs_Mouse1.40848146
48ELK3_25401928_ChIP-Seq_HUVEC_Human1.37678171
49DNAJC2_21179169_ChIP-ChIP_NT2_Human1.36837246
50GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.36811868
51RING1B_27294783_Chip-Seq_ESCs_Mouse1.36468500
52ESR1_20079471_ChIP-ChIP_T-47D_Human1.35925439
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.35425248
54KDM2B_26808549_Chip-Seq_DND41_Human1.33333564
55RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.32315718
56LXR_22292898_ChIP-Seq_THP-1_Human1.31024933
57* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30756796
58ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.30196658
59THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.28842894
60REST_18959480_ChIP-ChIP_MESCs_Mouse1.27667144
61RING1B_27294783_Chip-Seq_NPCs_Mouse1.26348482
62ZNF217_24962896_ChIP-Seq_MCF-7_Human1.24850291
63NFIB_24661679_ChIP-Seq_LUNG_Mouse1.22430329
64* ISL1_27105846_Chip-Seq_CPCs_Mouse1.21011793
65TP53_20018659_ChIP-ChIP_R1E_Mouse1.20472416
66KDM2B_26808549_Chip-Seq_JURKAT_Human1.19496140
67NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.19372801
68CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.19138472
69PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.16670744
70SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.16548477
71NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.15711381
72ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.14692320
73CTCF_27219007_Chip-Seq_Bcells_Human1.13145094
74AHR_22903824_ChIP-Seq_MCF-7_Human1.12936340
75P300_27058665_Chip-Seq_ZR-75-30cells_Human1.11958564
76* AR_19668381_ChIP-Seq_PC3_Human1.11526242
77ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10810285
78CREB1_26743006_Chip-Seq_LNCaP_Human1.10106233
79CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.08201307
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07885157
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07683896
82* TBX20_22328084_ChIP-Seq_HEART_Mouse1.07390735
83* TBX20_22080862_ChIP-Seq_HEART_Mouse1.07390735
84SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.06421924
85* CLOCK_20551151_ChIP-Seq_293T_Human1.06087172
86RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05795645
87PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.05780253
88RACK7_27058665_Chip-Seq_MCF-7_Human1.05263325
89CDX2_20551321_ChIP-Seq_CACO-2_Human1.03761660
90RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03645363
91RUNX1_27514584_Chip-Seq_MCF-7_Human1.03247801
92NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.02414594
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.02206489
94ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01653992
95OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.01643814
96GBX2_23144817_ChIP-Seq_PC3_Human1.01528949
97KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.00914747
98* TET1_21490601_ChIP-Seq_MESCs_Mouse1.00897933
99TCF7_22412390_ChIP-Seq_EML_Mouse1.00321123
100ARNT_22903824_ChIP-Seq_MCF-7_Human0.99422013
101KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98416623
102NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.98317528
103UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96951633
104SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96327343
105SMAD4_21741376_ChIP-Seq_HESCs_Human0.95762759
106ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94220756
107TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94165731
108FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.94146881
109CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93765357
110AR_21572438_ChIP-Seq_LNCaP_Human0.92578155
111* SMAD3_21741376_ChIP-Seq_HESCs_Human0.92448842
112SOX2_21211035_ChIP-Seq_LN229_Gbm0.91794854
113KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.91563254
114PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.91277895
115P68_20966046_ChIP-Seq_HELA_Human0.91077202
116TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.91020561
117TP53_16413492_ChIP-PET_HCT116_Human0.89977365
118RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.89438186
119SMC4_20622854_ChIP-Seq_HELA_Human0.88503512
120* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88268294
121* TP53_23651856_ChIP-Seq_MEFs_Mouse0.87757321
122KLF4_19829295_ChIP-Seq_ESCs_Human0.87452224

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.01299571
2MP0000751_myopathy2.86452256
3MP0005409_darkened_coat_color2.68976221
4MP0003705_abnormal_hypodermis_morpholog2.64550685
5MP0000566_synostosis2.48600538
6MP0003283_abnormal_digestive_organ2.41401247
7MP0005623_abnormal_meninges_morphology2.40206769
8MP0000579_abnormal_nail_morphology2.37204935
9MP0004270_analgesia2.35436735
10MP0003635_abnormal_synaptic_transmissio2.30330335
11MP0004084_abnormal_cardiac_muscle2.18707759
12MP0004145_abnormal_muscle_electrophysio2.16540712
13MP0009780_abnormal_chondrocyte_physiolo2.13384051
14MP0004858_abnormal_nervous_system2.12741516
15MP0002837_dystrophic_cardiac_calcinosis2.03836903
16MP0010234_abnormal_vibrissa_follicle1.89946280
17MP0004233_abnormal_muscle_weight1.83436413
18MP0004215_abnormal_myocardial_fiber1.82900081
19MP0004272_abnormal_basement_membrane1.78760906
20MP0009046_muscle_twitch1.75789134
21MP0005257_abnormal_intraocular_pressure1.70626749
22MP0000537_abnormal_urethra_morphology1.70505267
23MP0002063_abnormal_learning/memory/cond1.67960690
24MP0002249_abnormal_larynx_morphology1.60764703
25MP0004036_abnormal_muscle_relaxation1.56714879
26MP0002909_abnormal_adrenal_gland1.53694745
27MP0004087_abnormal_muscle_fiber1.53448615
28MP0000762_abnormal_tongue_morphology1.52352500
29MP0008438_abnormal_cutaneous_collagen1.51964478
30MP0005275_abnormal_skin_tensile1.51652105
31MP0000013_abnormal_adipose_tissue1.46990981
32MP0002234_abnormal_pharynx_morphology1.44436781
33MP0009745_abnormal_behavioral_response1.43785723
34MP0006138_congestive_heart_failure1.43065655
35MP0003137_abnormal_impulse_conducting1.42098118
36MP0008569_lethality_at_weaning1.41511111
37MP0004130_abnormal_muscle_cell1.38346598
38MP0000678_abnormal_parathyroid_gland1.36963702
39MP0002734_abnormal_mechanical_nocicepti1.36576173
40MP0005167_abnormal_blood-brain_barrier1.34661337
41MP0005503_abnormal_tendon_morphology1.33534322
42MP0002064_seizures1.31139161
43MP0008961_abnormal_basal_metabolism1.29214844
44MP0003122_maternal_imprinting1.27787667
45MP0005620_abnormal_muscle_contractility1.27219511
46MP0005423_abnormal_somatic_nervous1.26786860
47MP0005187_abnormal_penis_morphology1.25962892
48MP0000534_abnormal_ureter_morphology1.25454926
49MP0000003_abnormal_adipose_tissue1.24181730
50MP0005330_cardiomyopathy1.23860789
51MP0010030_abnormal_orbit_morphology1.22614684
52MP0003123_paternal_imprinting1.22122067
53MP0001348_abnormal_lacrimal_gland1.22039099
54MP0002184_abnormal_innervation1.21911992
55MP0002822_catalepsy1.21642831
56MP0004085_abnormal_heartbeat1.21043361
57MP0000462_abnormal_digestive_system1.20170106
58MP0002572_abnormal_emotion/affect_behav1.19922611
59MP0003385_abnormal_body_wall1.18933441
60MP0002796_impaired_skin_barrier1.17314382
61MP0004885_abnormal_endolymph1.16310267
62MP0001486_abnormal_startle_reflex1.16251380
63MP0002896_abnormal_bone_mineralization1.15808071
64MP0000778_abnormal_nervous_system1.14777069
65MP0002272_abnormal_nervous_system1.14443327
66MP0004484_altered_response_of1.14315317
67MP0000749_muscle_degeneration1.14256473
68MP0002972_abnormal_cardiac_muscle1.14136462
69MP0000467_abnormal_esophagus_morphology1.13349307
70MP0010368_abnormal_lymphatic_system1.11291033
71MP0000747_muscle_weakness1.10909716
72MP0000759_abnormal_skeletal_muscle1.10311739
73MP0010630_abnormal_cardiac_muscle1.10269664
74MP0003045_fibrosis1.10188629
75MP0008775_abnormal_heart_ventricle1.08749457
76MP0003880_abnormal_central_pattern1.07866761
77MP0001958_emphysema1.07704016
78MP0000750_abnormal_muscle_regeneration1.07588884
79MP0001502_abnormal_circadian_rhythm1.06577528
80MP0004811_abnormal_neuron_physiology1.06182494
81MP0003119_abnormal_digestive_system1.05629616
82MP0003634_abnormal_glial_cell1.05615030
83MP0005375_adipose_tissue_phenotype1.04832808
84MP0002653_abnormal_ependyma_morphology1.04171824
85MP0003115_abnormal_respiratory_system1.02925375
86MP0003329_amyloid_beta_deposits1.02857669
87MP0002106_abnormal_muscle_physiology1.02699866
88MP0001849_ear_inflammation1.02483494
89MP0005076_abnormal_cell_differentiation1.01298296
90MP0000955_abnormal_spinal_cord1.01183310
91MP0003091_abnormal_cell_migration0.99442162
92MP0002269_muscular_atrophy0.99085507
93MP0001440_abnormal_grooming_behavior0.97674544
94MP0005666_abnormal_adipose_tissue0.97181889
95MP0002060_abnormal_skin_morphology0.96222869
96MP0003566_abnormal_cell_adhesion0.95927177
97MP0002089_abnormal_postnatal_growth/wei0.95019423
98MP0005385_cardiovascular_system_phenoty0.94874607
99MP0001544_abnormal_cardiovascular_syste0.94874607
100MP0002733_abnormal_thermal_nociception0.94486378
101MP0000733_abnormal_muscle_development0.94473929
102MP0005369_muscle_phenotype0.94172486
103MP0009053_abnormal_anal_canal0.93537644
104MP0003646_muscle_fatigue0.92384737
105MP0001968_abnormal_touch/_nociception0.92026056
106MP0001299_abnormal_eye_distance/0.91711672
107MP0002108_abnormal_muscle_morphology0.90948443
108MP0003279_aneurysm0.90461943
109MP0004185_abnormal_adipocyte_glucose0.90010865
110MP0005670_abnormal_white_adipose0.89819800
111MP0009384_cardiac_valve_regurgitation0.88289965
112MP0003941_abnormal_skin_development0.87712648
113MP0001346_abnormal_lacrimal_gland0.85935146
114MP0002067_abnormal_sensory_capabilities0.84402816
115MP0003453_abnormal_keratinocyte_physiol0.84091781
116MP0002152_abnormal_brain_morphology0.83800951
117MP0005377_hearing/vestibular/ear_phenot0.83774664
118MP0003878_abnormal_ear_physiology0.83774664
119MP0002882_abnormal_neuron_morphology0.83383001
120MP0003942_abnormal_urinary_system0.82708279
121MP0002557_abnormal_social/conspecific_i0.82621126
122MP0005508_abnormal_skeleton_morphology0.81938518
123MP0001177_atelectasis0.81576215
124MP0001501_abnormal_sleep_pattern0.81463589
125MP0003879_abnormal_hair_cell0.80441700
126MP0000767_abnormal_smooth_muscle0.80108157
127MP0001970_abnormal_pain_threshold0.79487999
128MP0005595_abnormal_vascular_smooth0.77691499
129MP0002098_abnormal_vibrissa_morphology0.77690319
130MP0005023_abnormal_wound_healing0.77247114
131MP0005248_abnormal_Harderian_gland0.75907854
132MP0000920_abnormal_myelination0.73897164
133MP0001879_abnormal_lymphatic_vessel0.73390671
134MP0002116_abnormal_craniofacial_bone0.72191558
135MP0004264_abnormal_extraembryonic_tissu0.71278244
136MP0003690_abnormal_glial_cell0.71202683
137MP0004782_abnormal_surfactant_physiolog0.70333350
138MP0002066_abnormal_motor_capabilities/c0.69227093

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)3.51713670
2Shallow orbits (HP:0000586)3.19131288
3Myokymia (HP:0002411)3.18649310
4Sudden death (HP:0001699)3.12893599
5Abnormality of the lower motor neuron (HP:0002366)2.97975272
6Broad metatarsal (HP:0001783)2.97600990
7Neurofibrillary tangles (HP:0002185)2.94373892
8Difficulty running (HP:0009046)2.93167464
9Action tremor (HP:0002345)2.92344672
10Ventricular fibrillation (HP:0001663)2.83889086
11Cerebral aneurysm (HP:0004944)2.82723380
12Right ventricular cardiomyopathy (HP:0011663)2.69483801
13Increased variability in muscle fiber diameter (HP:0003557)2.67521070
14Bundle branch block (HP:0011710)2.64561045
15Increased connective tissue (HP:0009025)2.62159797
16Focal seizures (HP:0007359)2.60755754
17Hyporeflexia of lower limbs (HP:0002600)2.60255823
18Hyperacusis (HP:0010780)2.59502676
19Dysmetric saccades (HP:0000641)2.59309641
20Visual hallucinations (HP:0002367)2.57289782
21Protrusio acetabuli (HP:0003179)2.55573354
22Cerebral inclusion bodies (HP:0100314)2.53459154
23Type 1 muscle fiber predominance (HP:0003803)2.52882193
24Neonatal short-limb short stature (HP:0008921)2.47158480
25Exercise-induced myalgia (HP:0003738)2.46831985
26Mildly elevated creatine phosphokinase (HP:0008180)2.39835097
27Insomnia (HP:0100785)2.38660797
28Renal duplication (HP:0000075)2.35180499
29Focal motor seizures (HP:0011153)2.32795200
30Prolonged QT interval (HP:0001657)2.30037668
31Vascular tortuosity (HP:0004948)2.29951704
32Arterial tortuosity (HP:0005116)2.27156595
33Elfin facies (HP:0004428)2.26922615
34Distal upper limb amyotrophy (HP:0007149)2.25724400
35Upper limb amyotrophy (HP:0009129)2.25724400
36Abnormality of skeletal muscle fiber size (HP:0012084)2.25714875
37Myotonia (HP:0002486)2.25412144
38Hemiplegia (HP:0002301)2.23830262
39Pointed chin (HP:0000307)2.23723182
40Bladder diverticulum (HP:0000015)2.21950691
41Neoplasm of the heart (HP:0100544)2.21470092
42Annular pancreas (HP:0001734)2.17693380
43Difficulty climbing stairs (HP:0003551)2.16452535
44Atrial fibrillation (HP:0005110)2.16370655
45Muscle fiber splitting (HP:0003555)2.14954125
46Ankle contracture (HP:0006466)2.14420999
47Progressive cerebellar ataxia (HP:0002073)2.14352478
48Bronchomalacia (HP:0002780)2.12564758
49Syncope (HP:0001279)2.12121627
50Primary atrial arrhythmia (HP:0001692)2.09463218
51Distal lower limb amyotrophy (HP:0008944)2.08258852
52Renovascular hypertension (HP:0100817)2.07104497
53Bowel diverticulosis (HP:0005222)2.06140703
54Ulnar bowing (HP:0003031)2.05912757
55Atrophic scars (HP:0001075)2.04801592
56Distal lower limb muscle weakness (HP:0009053)2.03284760
57Exercise-induced muscle cramps (HP:0003710)2.02076717
58Ventricular tachycardia (HP:0004756)2.00979322
59Lymphangioma (HP:0100764)2.00947698
60Supraventricular arrhythmia (HP:0005115)1.99898653
61Ventricular arrhythmia (HP:0004308)1.99847702
62Genetic anticipation (HP:0003743)1.99051425
63Abnormality of the calf musculature (HP:0001430)1.98866618
64Overriding aorta (HP:0002623)1.97662543
65Ankle clonus (HP:0011448)1.97431939
66Wormian bones (HP:0002645)1.96241890
67Buphthalmos (HP:0000557)1.95225972
68Flat cornea (HP:0007720)1.94962531
69Hand muscle atrophy (HP:0009130)1.94641360
70Supraventricular tachycardia (HP:0004755)1.93464065
71Coronal craniosynostosis (HP:0004440)1.92973291
72Dysdiadochokinesis (HP:0002075)1.92959464
73Broad face (HP:0000283)1.92576591
74Advanced eruption of teeth (HP:0006288)1.90974793
75Ankyloglossia (HP:0010296)1.89658403
76Aortic aneurysm (HP:0004942)1.89040831
77Abnormal social behavior (HP:0012433)1.86599154
78Impaired social interactions (HP:0000735)1.86599154
79Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.86373045
80Short 4th metacarpal (HP:0010044)1.86373045
81Achilles tendon contracture (HP:0001771)1.83341268
82Poor eye contact (HP:0000817)1.82784886
83Turricephaly (HP:0000262)1.82352365
84Hypoventilation (HP:0002791)1.81954467
85Abnormal EKG (HP:0003115)1.81927154
86Spinal rigidity (HP:0003306)1.81068034
87Fragile skin (HP:0001030)1.79641403
88Round ear (HP:0100830)1.79608958
89Scapular winging (HP:0003691)1.78665529
90Flat acetabular roof (HP:0003180)1.78483707
91Vertebral arch anomaly (HP:0008438)1.78285071
92Mitral regurgitation (HP:0001653)1.78268058
93Lower limb amyotrophy (HP:0007210)1.77022677
94Mitral valve prolapse (HP:0001634)1.76189529
95Abnormality of the 4th metacarpal (HP:0010012)1.75476232
96Depression (HP:0000716)1.74059765
97Aortic dissection (HP:0002647)1.73419026
98Milia (HP:0001056)1.73164602
99Aneurysm (HP:0002617)1.73059701
100Overgrowth (HP:0001548)1.72870105
101Aplasia involving bones of the upper limbs (HP:0009823)1.72825372
102Aplasia of the phalanges of the hand (HP:0009802)1.72825372
103Aplasia involving bones of the extremities (HP:0009825)1.72825372
104Megalencephaly (HP:0001355)1.72527291
105Torticollis (HP:0000473)1.71873204
106Enlarged penis (HP:0000040)1.71257081
107Premature rupture of membranes (HP:0001788)1.70234552
108Atonic seizures (HP:0010819)1.70080344
109Macroorchidism (HP:0000053)1.69282382
110Heart block (HP:0012722)1.68828044
111Centrally nucleated skeletal muscle fibers (HP:0003687)1.68744392
112Rapidly progressive (HP:0003678)1.66335426
113Abnormality of the distal phalanx of the thumb (HP:0009617)1.65512944
114Hyperparathyroidism (HP:0000843)1.65292144
115Cervical subluxation (HP:0003308)1.64932540
116EMG: myopathic abnormalities (HP:0003458)1.64647222
117Pterygium (HP:0001059)1.64385895
118Abnormal atrioventricular conduction (HP:0005150)1.64320374
119Hyperextensible skin (HP:0000974)1.63554541
120Calf muscle hypertrophy (HP:0008981)1.62504232
121Akinesia (HP:0002304)1.61651061
122Foot dorsiflexor weakness (HP:0009027)1.61527088
123Arnold-Chiari malformation (HP:0002308)1.60053409
124Hammertoe (HP:0001765)1.59859044
125Abnormality of the salivary glands (HP:0010286)1.58634873
126Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.58544539
127Abnormality of carpal bone ossification (HP:0006257)1.58511542
128Stridor (HP:0010307)1.58249767
129Insidious onset (HP:0003587)1.58160381
130Termporal pattern (HP:0011008)1.58160381
131Myopathic facies (HP:0002058)1.57774519
132Hemiparesis (HP:0001269)1.57663618
133Supranuclear gaze palsy (HP:0000605)1.57012442
134Absence seizures (HP:0002121)1.56720888
135Deviation of the hallux (HP:0010051)1.55826768
136Spinal cord compression (HP:0002176)1.55732243
137Thin ribs (HP:0000883)1.54515323
138Neonatal death (HP:0003811)1.52649241
139Limited hip movement (HP:0008800)1.52596388
140Abnormality of the Achilles tendon (HP:0005109)1.52305158
141Abnormal ossification of hand bones (HP:0005921)1.51887956
142Visceral angiomatosis (HP:0100761)1.50978106
143Hypercortisolism (HP:0001578)1.50850950
144Deep venous thrombosis (HP:0002625)1.49538666
145Hypoplasia of the iris (HP:0007676)1.49344377

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.13982449
2MAP3K92.63410332
3PRKD32.48874776
4LMTK22.11984395
5PKN22.10067792
6TTN2.06339853
7PAK62.05131434
8PDGFRA2.00371313
9LATS21.99624835
10DDR21.94845743
11NTRK31.94698354
12DAPK21.87921170
13MST1R1.87813388
14EPHA41.82788860
15TYRO31.81863050
16PHKG21.81048619
17PHKG11.81048619
18MARK11.80155877
19KSR21.77162095
20STK381.68226209
21CAMKK11.67556661
22MINK11.64271851
23DMPK1.63554218
24ICK1.63086460
25FGFR41.62199371
26PRPF4B1.61636584
27EPHB21.59611726
28CAMK1G1.58498907
29MAP3K41.56259934
30NTRK11.55381968
31SMG11.45622050
32CAMK1D1.35084309
33FER1.32317738
34NEK11.32178324
35TESK11.29591429
36TAOK11.29105339
37NTRK21.28149885
38ARAF1.25651441
39PTK61.25573155
40KSR11.15133725
41MAP2K41.13884015
42PAK31.13389064
43PTK21.12258354
44RET1.10346178
45TIE11.09689495
46CDC42BPA1.09321973
47SIK11.08270046
48MAP3K21.08127923
49WNK11.02022977
50LATS11.00876590
51SIK20.98859980
52BMX0.97621154
53PTK2B0.95950894
54CDK50.93101353
55ERN10.92042731
56CAMKK20.90662887
57ALK0.90655252
58EEF2K0.90389618
59PRKCH0.90056672
60STK110.88496934
61FGFR20.87838591
62MAP3K70.86402788
63MAP3K60.85510786
64MARK20.83777086
65CAMK2B0.82941917
66MAP3K100.82894421
67FGFR10.80942624
68CAMK2G0.77736846
69EPHB10.76844435
70CAMK10.75434793
71MTOR0.73240298
72PDK40.72891312
73PDK30.72891312
74CAMK40.71043233
75ROCK10.70020136
76PRKD10.69629188
77GRK50.68432195
78UHMK10.67838450
79MAPK120.67576212
80CASK0.64729500
81CDK120.63588388
82LIMK10.63371939
83ERBB20.62016031
84SCYL20.61615711
85PDGFRB0.60560307
86CDK150.60247692
87TAOK20.59838804
88MAP2K10.59820361
89NEK60.59614811
90DAPK30.58665070
91SGK30.58367791
92CDK140.58012824
93MAPK100.57912220
94ROCK20.57901844
95PAK40.57889536
96PAK20.56552352
97CDK180.55679994
98OBSCN0.54668170
99MAP3K130.52800565
100SGK20.52494502
101EPHA20.52088889
102RPS6KA20.51938071
103PRKG20.51832255
104ILK0.51825808
105PDPK10.51356479
106PRKD20.51198913
107CAMK2D0.50985864
108PRKAA10.50418412
109DAPK10.50083385
110CDK11A0.49522850
111MET0.49180128
112FGFR30.48497120
113MYLK0.48382219
114MAPKAPK30.46503780
115RPS6KA30.45867005
116DYRK1B0.45288342
117PRKCG0.44427989
118PNCK0.43825662
119SGK10.43815990
120MAP3K10.42083316
121SRC0.41983769
122BRAF0.41890682
123SGK4940.41642782
124SGK2230.41642782

Predicted pathways (KEGG)

RankGene SetZ-score
1Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.04264466
2Circadian entrainment_Homo sapiens_hsa047131.99711675
3Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.83873791
4Dilated cardiomyopathy_Homo sapiens_hsa054141.82079423
5Long-term potentiation_Homo sapiens_hsa047201.80300501
6Nicotine addiction_Homo sapiens_hsa050331.77269930
7Olfactory transduction_Homo sapiens_hsa047401.77059831
8Glutamatergic synapse_Homo sapiens_hsa047241.75323966
9Salivary secretion_Homo sapiens_hsa049701.71528920
10Gastric acid secretion_Homo sapiens_hsa049711.69947647
11GABAergic synapse_Homo sapiens_hsa047271.69816579
12Synaptic vesicle cycle_Homo sapiens_hsa047211.68228250
13Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.64520252
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.63891069
15Aldosterone synthesis and secretion_Homo sapiens_hsa049251.62320545
16Insulin secretion_Homo sapiens_hsa049111.54015448
17Morphine addiction_Homo sapiens_hsa050321.51788383
18Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.49461842
19Dopaminergic synapse_Homo sapiens_hsa047281.47783959
20Renin secretion_Homo sapiens_hsa049241.47705606
21Oxytocin signaling pathway_Homo sapiens_hsa049211.47068640
22Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.45445573
23Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.44866636
24Cholinergic synapse_Homo sapiens_hsa047251.43984329
25Amphetamine addiction_Homo sapiens_hsa050311.40153644
26Gap junction_Homo sapiens_hsa045401.39773708
27GnRH signaling pathway_Homo sapiens_hsa049121.34718025
28Estrogen signaling pathway_Homo sapiens_hsa049151.29638124
29Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.28871518
30cGMP-PKG signaling pathway_Homo sapiens_hsa040221.27567552
31Cyanoamino acid metabolism_Homo sapiens_hsa004601.27128884
32Arginine biosynthesis_Homo sapiens_hsa002201.26717756
33Prion diseases_Homo sapiens_hsa050201.26035422
34Long-term depression_Homo sapiens_hsa047301.25739141
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.25351091
36Cardiac muscle contraction_Homo sapiens_hsa042601.24910041
37Nitrogen metabolism_Homo sapiens_hsa009101.24808245
38Axon guidance_Homo sapiens_hsa043601.24280436
39Melanogenesis_Homo sapiens_hsa049161.22651361
40Type II diabetes mellitus_Homo sapiens_hsa049301.22024129
41Tight junction_Homo sapiens_hsa045301.18949135
42Taste transduction_Homo sapiens_hsa047421.17545595
43Focal adhesion_Homo sapiens_hsa045101.16478595
44Calcium signaling pathway_Homo sapiens_hsa040201.14166172
45Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.14089056
46Glioma_Homo sapiens_hsa052141.13475896
47cAMP signaling pathway_Homo sapiens_hsa040241.12062602
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11948112
49ECM-receptor interaction_Homo sapiens_hsa045121.09374454
50Dorso-ventral axis formation_Homo sapiens_hsa043201.07934460
51Hippo signaling pathway_Homo sapiens_hsa043901.07267026
52Basal cell carcinoma_Homo sapiens_hsa052171.07004552
53mTOR signaling pathway_Homo sapiens_hsa041501.06070467
54Thyroid hormone signaling pathway_Homo sapiens_hsa049191.05581598
55Cocaine addiction_Homo sapiens_hsa050301.03337668
56Vascular smooth muscle contraction_Homo sapiens_hsa042701.02519338
57Proteoglycans in cancer_Homo sapiens_hsa052051.00298468
58Endometrial cancer_Homo sapiens_hsa052131.00264805
59Hedgehog signaling pathway_Homo sapiens_hsa043400.97448221
60Adherens junction_Homo sapiens_hsa045200.96319257
61VEGF signaling pathway_Homo sapiens_hsa043700.95299395
62Phosphatidylinositol signaling system_Homo sapiens_hsa040700.94058610
63Fatty acid biosynthesis_Homo sapiens_hsa000610.93413260
64Central carbon metabolism in cancer_Homo sapiens_hsa052300.92481729
65Arginine and proline metabolism_Homo sapiens_hsa003300.92200208
66Longevity regulating pathway - mammal_Homo sapiens_hsa042110.91435466
67Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90654851
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89784521
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.89351210
70ErbB signaling pathway_Homo sapiens_hsa040120.89296027
71Rap1 signaling pathway_Homo sapiens_hsa040150.89081564
72Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88797080
73Thyroid hormone synthesis_Homo sapiens_hsa049180.88677279
74Histidine metabolism_Homo sapiens_hsa003400.87957525
75Bile secretion_Homo sapiens_hsa049760.86594111
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.86577989
77Glucagon signaling pathway_Homo sapiens_hsa049220.86505809
78Insulin signaling pathway_Homo sapiens_hsa049100.86214647
79Pancreatic secretion_Homo sapiens_hsa049720.86166683
80Vitamin B6 metabolism_Homo sapiens_hsa007500.85451792
81Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.82486758
82Protein digestion and absorption_Homo sapiens_hsa049740.81907473
83Phenylalanine metabolism_Homo sapiens_hsa003600.80337629
84Serotonergic synapse_Homo sapiens_hsa047260.79542921
85PPAR signaling pathway_Homo sapiens_hsa033200.78324842
86Wnt signaling pathway_Homo sapiens_hsa043100.77100990
87Amoebiasis_Homo sapiens_hsa051460.76610057
88Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.76514032
89Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.76425099
90AMPK signaling pathway_Homo sapiens_hsa041520.75987936
91Oocyte meiosis_Homo sapiens_hsa041140.74117077
92Renal cell carcinoma_Homo sapiens_hsa052110.73836533
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73717128
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.73084277
95Inositol phosphate metabolism_Homo sapiens_hsa005620.70984046
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69022528
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68018853
98Insulin resistance_Homo sapiens_hsa049310.66284822
99Bladder cancer_Homo sapiens_hsa052190.65833841
100Circadian rhythm_Homo sapiens_hsa047100.65440377
101Choline metabolism in cancer_Homo sapiens_hsa052310.63183084
102MAPK signaling pathway_Homo sapiens_hsa040100.62786061
103Thyroid cancer_Homo sapiens_hsa052160.61115667
104Colorectal cancer_Homo sapiens_hsa052100.59750393
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59625990
106Non-small cell lung cancer_Homo sapiens_hsa052230.59543394
107AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.58648431
108MicroRNAs in cancer_Homo sapiens_hsa052060.57045249
109Notch signaling pathway_Homo sapiens_hsa043300.56470202
110Endocytosis_Homo sapiens_hsa041440.56090829
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.55842086
112Vibrio cholerae infection_Homo sapiens_hsa051100.55601963
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55306620
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55188577
115Ras signaling pathway_Homo sapiens_hsa040140.54179838
116Chronic myeloid leukemia_Homo sapiens_hsa052200.53413016
117Fructose and mannose metabolism_Homo sapiens_hsa000510.52563318
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.51875153

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