DACT3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)7.10379051
2axon ensheathment in central nervous system (GO:0032291)7.10379051
3behavioral response to nicotine (GO:0035095)4.86255485
4neuron cell-cell adhesion (GO:0007158)4.66171987
5synaptic vesicle maturation (GO:0016188)4.55681396
6myelination (GO:0042552)4.52879904
7axon ensheathment (GO:0008366)4.50011444
8ensheathment of neurons (GO:0007272)4.50011444
9fatty acid elongation (GO:0030497)4.31337099
10dendritic spine morphogenesis (GO:0060997)4.25191481
11neuronal action potential propagation (GO:0019227)4.23530275
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.21465581
13neuronal ion channel clustering (GO:0045161)4.11265721
14positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.08636893
15presynaptic membrane assembly (GO:0097105)4.05523972
16presynaptic membrane organization (GO:0097090)4.02280558
17long-chain fatty acid biosynthetic process (GO:0042759)4.00282072
18vocalization behavior (GO:0071625)4.00161155
19establishment of mitochondrion localization (GO:0051654)3.99505798
20synaptic vesicle exocytosis (GO:0016079)3.99386999
21glutamate secretion (GO:0014047)3.95791076
22locomotory exploration behavior (GO:0035641)3.90842151
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.89163040
24regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.81368821
25protein localization to synapse (GO:0035418)3.79193484
26neuronal action potential (GO:0019228)3.78874375
27L-amino acid import (GO:0043092)3.75993021
28negative regulation of neurotransmitter transport (GO:0051589)3.69630113
29detection of calcium ion (GO:0005513)3.68619077
30regulation of synaptic vesicle exocytosis (GO:2000300)3.67041449
31membrane depolarization during action potential (GO:0086010)3.66563038
32neuron recognition (GO:0008038)3.65813149
33cAMP catabolic process (GO:0006198)3.55352360
34layer formation in cerebral cortex (GO:0021819)3.54900458
35primary amino compound metabolic process (GO:1901160)3.54524798
36ionotropic glutamate receptor signaling pathway (GO:0035235)3.53146521
37transmission of nerve impulse (GO:0019226)3.52987589
38positive regulation of prostaglandin secretion (GO:0032308)3.52619955
39response to pheromone (GO:0019236)3.51699706
40negative regulation of protein localization to cell surface (GO:2000009)3.45013744
41pyrimidine nucleobase catabolic process (GO:0006208)3.43374757
42negative regulation of neurotransmitter secretion (GO:0046929)3.39193550
43regulation of neuronal synaptic plasticity (GO:0048168)3.37947100
44adult walking behavior (GO:0007628)3.36950879
45regulation of dendritic spine morphogenesis (GO:0061001)3.34881865
46cyclic nucleotide catabolic process (GO:0009214)3.33285296
47axonal fasciculation (GO:0007413)3.29304892
48regulation of glutamate receptor signaling pathway (GO:1900449)3.28625828
49apical protein localization (GO:0045176)3.24817532
50synaptic transmission, glutamatergic (GO:0035249)3.22647845
51negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.22561046
52serotonin metabolic process (GO:0042428)3.21235982
53positive regulation of fatty acid transport (GO:2000193)3.20141046
54glutamate receptor signaling pathway (GO:0007215)3.17707693
55regulation of long-term neuronal synaptic plasticity (GO:0048169)3.13868420
56neuron-neuron synaptic transmission (GO:0007270)3.08959539
57exploration behavior (GO:0035640)3.08686983
58oligodendrocyte differentiation (GO:0048709)3.08281864
59protein polyglutamylation (GO:0018095)3.07717174
60negative regulation of cytosolic calcium ion concentration (GO:0051481)3.06443422
61gamma-aminobutyric acid transport (GO:0015812)3.05719446
62gamma-aminobutyric acid signaling pathway (GO:0007214)3.05449895
63regulation of synaptic vesicle transport (GO:1902803)3.05298769
64positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.03924472
65negative regulation of synaptic transmission, GABAergic (GO:0032229)3.02515095
66long-term memory (GO:0007616)3.00200370
67regulation of dendritic spine development (GO:0060998)3.00121619
68neuromuscular synaptic transmission (GO:0007274)2.99673283
69action potential (GO:0001508)2.99066877
70positive regulation of membrane potential (GO:0045838)2.99011196
71negative regulation of axonogenesis (GO:0050771)2.98804834
72startle response (GO:0001964)2.97125661
73dendrite morphogenesis (GO:0048813)2.96248695
74regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.95228375
75cerebral cortex radially oriented cell migration (GO:0021799)2.95058341
76nucleobase catabolic process (GO:0046113)2.93802177
77calcium ion-dependent exocytosis (GO:0017156)2.92442787
78cerebellar Purkinje cell differentiation (GO:0021702)2.91846598
79asymmetric protein localization (GO:0008105)2.88363443
80regulation of excitatory postsynaptic membrane potential (GO:0060079)2.88277221
81mating behavior (GO:0007617)2.87729849
82amino acid import (GO:0043090)2.87267041
83positive regulation of dendritic spine development (GO:0060999)2.86491617
84peptidyl-tyrosine autophosphorylation (GO:0038083)2.86001343
85L-fucose catabolic process (GO:0042355)2.85714826
86fucose catabolic process (GO:0019317)2.85714826
87L-fucose metabolic process (GO:0042354)2.85714826
88synaptic vesicle docking involved in exocytosis (GO:0016081)2.85065828
89G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.84387097
90postsynaptic membrane organization (GO:0001941)2.83260420
91neurotransmitter secretion (GO:0007269)2.83156493
92regulation of collateral sprouting (GO:0048670)2.82074174
93dendritic spine organization (GO:0097061)2.80056000
94regulation of prostaglandin secretion (GO:0032306)2.79860303
95positive regulation of icosanoid secretion (GO:0032305)2.77842381
96regulation of voltage-gated calcium channel activity (GO:1901385)2.77750504
97C4-dicarboxylate transport (GO:0015740)2.76848163
98regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.76685566
99response to methylmercury (GO:0051597)2.76479129
100regulation of endothelial cell differentiation (GO:0045601)2.76088394
101myelin maintenance (GO:0043217)2.75102998
102membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.75071839
103glycerophospholipid catabolic process (GO:0046475)2.75018356
104auditory behavior (GO:0031223)2.74778901
105acrosome reaction (GO:0007340)2.72059412
106establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.71848605
107mitochondrion transport along microtubule (GO:0047497)2.71848605
108regulation of postsynaptic membrane potential (GO:0060078)2.71580629
109substantia nigra development (GO:0021762)2.70826255
110regulation of action potential (GO:0098900)2.69922456
111membrane depolarization (GO:0051899)2.69580175
112positive regulation of synapse assembly (GO:0051965)2.69032683
113regulation of synaptic plasticity (GO:0048167)2.68531329
114neurotransmitter-gated ion channel clustering (GO:0072578)2.68283854
115cerebellar granule cell differentiation (GO:0021707)2.67884688
116astrocyte development (GO:0014002)2.67683447
117mechanosensory behavior (GO:0007638)2.67063146
118replicative senescence (GO:0090399)2.65545361
119regulation of synapse structural plasticity (GO:0051823)2.63444553
120eye photoreceptor cell differentiation (GO:0001754)2.62429218
121photoreceptor cell differentiation (GO:0046530)2.62429218
122regulation of neurotransmitter transport (GO:0051588)2.61679166
123neuron remodeling (GO:0016322)2.61504683
124neurotransmitter transport (GO:0006836)2.60412785
125neuromuscular process controlling balance (GO:0050885)2.59672961
126glycine transport (GO:0015816)2.59376528
127negative regulation of axon extension (GO:0030517)2.58690257
128regulation of neurotransmitter secretion (GO:0046928)2.58643237
129regulation of vesicle fusion (GO:0031338)2.57817793
130cAMP metabolic process (GO:0046058)2.57817467
131nerve growth factor signaling pathway (GO:0038180)2.57582975
132detection of light stimulus involved in visual perception (GO:0050908)2.57565258
133detection of light stimulus involved in sensory perception (GO:0050962)2.57565258
134peripheral nervous system axon ensheathment (GO:0032292)2.57303307
135myelination in peripheral nervous system (GO:0022011)2.57303307
136membrane assembly (GO:0071709)2.57018898
137hematopoietic stem cell proliferation (GO:0071425)2.56841482
138urinary tract smooth muscle contraction (GO:0014848)2.56160667
139detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.55235507
140regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.54666096
141neurofilament cytoskeleton organization (GO:0060052)2.54573032
142long-term synaptic potentiation (GO:0060291)2.54350040
143membrane hyperpolarization (GO:0060081)2.52664752
144positive regulation of sodium ion transmembrane transport (GO:1902307)2.51526081
145proline transport (GO:0015824)2.50638212
146indole-containing compound metabolic process (GO:0042430)2.49629281
147positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.47674680
148regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.46047730
149cellular potassium ion transport (GO:0071804)2.45633873
150potassium ion transmembrane transport (GO:0071805)2.45633873
151regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.45019761
152regulation of membrane repolarization (GO:0060306)2.44739976
153regulation of microtubule-based movement (GO:0060632)2.43934381
154regulation of neurotransmitter uptake (GO:0051580)2.43267219
155regulation of cell communication by electrical coupling (GO:0010649)2.42590463
156indolalkylamine metabolic process (GO:0006586)2.42565986
157response to auditory stimulus (GO:0010996)2.42500313
158synapse assembly (GO:0007416)2.42314305
159epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.41692884
160cellular ketone body metabolic process (GO:0046950)2.41273850

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.84999492
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.96255201
3GBX2_23144817_ChIP-Seq_PC3_Human3.36218290
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.19693911
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.07276884
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.06049244
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.80811944
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.80811944
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.78543715
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.62296538
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.56978325
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.53479484
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.53289551
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.53143328
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.51513333
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.43281729
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.37326437
18SUZ12_27294783_Chip-Seq_ESCs_Mouse2.35895372
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.30866990
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.26909022
21DROSHA_22980978_ChIP-Seq_HELA_Human2.18599794
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.07302514
23* REST_21632747_ChIP-Seq_MESCs_Mouse2.01681603
24TAF15_26573619_Chip-Seq_HEK293_Human1.91693832
25BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.88646144
26IGF1R_20145208_ChIP-Seq_DFB_Human1.87609288
27AR_21572438_ChIP-Seq_LNCaP_Human1.79096368
28SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.75551947
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.75255611
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.74473608
31PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.73278628
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.67903735
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.64538124
34RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.61576223
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.57925730
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.56885388
37NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.53591477
38OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.49776761
39ERG_21242973_ChIP-ChIP_JURKAT_Human1.47504061
40GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.47295160
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.45738019
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.45035384
43TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44805585
44POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.44805585
45ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43553601
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41262166
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.39683616
48VDR_22108803_ChIP-Seq_LS180_Human1.37974247
49RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36116591
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.35964333
51PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34079578
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33420800
53RING1B_27294783_Chip-Seq_NPCs_Mouse1.29408830
54BCAT_22108803_ChIP-Seq_LS180_Human1.27144013
55SMAD4_21799915_ChIP-Seq_A2780_Human1.25568161
56EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25530754
57MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25285756
58TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23810434
59MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23787263
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.22279853
61WT1_25993318_ChIP-Seq_PODOCYTE_Human1.22107410
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.21372620
63IRF1_19129219_ChIP-ChIP_H3396_Human1.21291712
64SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20658112
65CBP_20019798_ChIP-Seq_JUKART_Human1.19147849
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.19147849
67P300_19829295_ChIP-Seq_ESCs_Human1.18510192
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.17137590
69ER_23166858_ChIP-Seq_MCF-7_Human1.16755751
70MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13400839
71CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.13194650
72TP53_22573176_ChIP-Seq_HFKS_Human1.10181090
73RNF2_27304074_Chip-Seq_NSC_Mouse1.09719216
74TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08646470
75TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08464290
76WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.07221033
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06565289
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06077563
79* SOX2_21211035_ChIP-Seq_LN229_Gbm1.06032192
80STAT3_23295773_ChIP-Seq_U87_Human1.05306815
81NR3C1_23031785_ChIP-Seq_PC12_Mouse1.05203570
82EWS_26573619_Chip-Seq_HEK293_Human1.05045309
83FLI1_21867929_ChIP-Seq_TH2_Mouse1.03954986
84PCGF2_27294783_Chip-Seq_ESCs_Mouse1.02826187
85* ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02235265
86SMAD4_21741376_ChIP-Seq_EPCs_Human1.02117595
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.01959775
88EP300_21415370_ChIP-Seq_HL-1_Mouse1.01833274
89P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00541973
90SMAD3_21741376_ChIP-Seq_ESCs_Human1.00465776
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00414578
92EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00274482
93POU3F2_20337985_ChIP-ChIP_501MEL_Human0.98579249
94DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98306183
95STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.98237083
96PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98079379
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98054032
98PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97631386
99TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97237672
100KDM2B_26808549_Chip-Seq_REH_Human0.97024700
101PRDM14_20953172_ChIP-Seq_ESCs_Human0.96980549
102ZNF274_21170338_ChIP-Seq_K562_Hela0.96643935
103FUS_26573619_Chip-Seq_HEK293_Human0.95277308
104TCF4_23295773_ChIP-Seq_U87_Human0.95228530
105TRIM28_21343339_ChIP-Seq_HEK293_Human0.94635005
106NANOG_19829295_ChIP-Seq_ESCs_Human0.94494761
107SOX2_19829295_ChIP-Seq_ESCs_Human0.94494761
108ARNT_22903824_ChIP-Seq_MCF-7_Human0.93948540
109* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.93387797
110NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92670996
111* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.92549437
112PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.92007697
113* AR_19668381_ChIP-Seq_PC3_Human0.91860629
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91714760
115ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91503407
116AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91258097
117AR_25329375_ChIP-Seq_VCAP_Human0.90614656
118AHR_22903824_ChIP-Seq_MCF-7_Human0.90404836
119TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90331165
120ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.89464226
121TP53_16413492_ChIP-PET_HCT116_Human0.88868501
122WT1_19549856_ChIP-ChIP_CCG9911_Human0.87328252
123RUNX2_22187159_ChIP-Seq_PCA_Human0.86667925
124KDM2B_26808549_Chip-Seq_K562_Human0.83744523
125NRF2_20460467_ChIP-Seq_MEFs_Mouse0.83212927
126NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.83212927
127* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.82716429
128YAP1_20516196_ChIP-Seq_MESCs_Mouse0.82466860
129LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82205842
130* CTCF_27219007_Chip-Seq_Bcells_Human0.81973441

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.98409517
2MP0004859_abnormal_synaptic_plasticity4.95420008
3MP0004270_analgesia3.82719602
4MP0003635_abnormal_synaptic_transmissio3.31736036
5MP0000920_abnormal_myelination3.04187552
6MP0002064_seizures2.81685382
7MP0009745_abnormal_behavioral_response2.77008717
8MP0001486_abnormal_startle_reflex2.73424650
9MP0002063_abnormal_learning/memory/cond2.67183438
10MP0002272_abnormal_nervous_system2.65228805
11MP0003646_muscle_fatigue2.53778416
12MP0005423_abnormal_somatic_nervous2.45656514
13MP0009046_muscle_twitch2.44880307
14MP0002572_abnormal_emotion/affect_behav2.38996804
15MP0002734_abnormal_mechanical_nocicepti2.37715319
16MP0003329_amyloid_beta_deposits2.34107039
17MP0000778_abnormal_nervous_system2.27162478
18MP0001968_abnormal_touch/_nociception2.17978612
19MP0001529_abnormal_vocalization2.11404632
20MP0008872_abnormal_physiological_respon2.02371620
21MP0001905_abnormal_dopamine_level1.99093313
22MP0004742_abnormal_vestibular_system1.99067512
23MP0004885_abnormal_endolymph1.99038292
24MP0001440_abnormal_grooming_behavior1.96505126
25MP0003787_abnormal_imprinting1.85852341
26MP0000013_abnormal_adipose_tissue1.83800243
27MP0002638_abnormal_pupillary_reflex1.82504338
28MP0003690_abnormal_glial_cell1.76485856
29MP0001485_abnormal_pinna_reflex1.75104465
30MP0002822_catalepsy1.74101996
31MP0000569_abnormal_digit_pigmentation1.71260495
32MP0002067_abnormal_sensory_capabilities1.70095497
33MP0004142_abnormal_muscle_tone1.69073644
34MP0001970_abnormal_pain_threshold1.68285119
35MP0002733_abnormal_thermal_nociception1.66932256
36MP0000955_abnormal_spinal_cord1.66856258
37MP0002736_abnormal_nociception_after1.63633133
38MP0004130_abnormal_muscle_cell1.61180610
39MP0003634_abnormal_glial_cell1.58058553
40MP0003950_abnormal_plasma_membrane1.56732734
41MP0008569_lethality_at_weaning1.55048614
42MP0002882_abnormal_neuron_morphology1.54870969
43MP0002735_abnormal_chemical_nociception1.54870001
44MP0001501_abnormal_sleep_pattern1.52645462
45MP0002876_abnormal_thyroid_physiology1.51296685
46MP0008877_abnormal_DNA_methylation1.51007515
47MP0004924_abnormal_behavior1.48724576
48MP0005386_behavior/neurological_phenoty1.48724576
49MP0002066_abnormal_motor_capabilities/c1.44674522
50MP0002184_abnormal_innervation1.41972342
51MP0001986_abnormal_taste_sensitivity1.38783837
52MP0002229_neurodegeneration1.38426411
53MP0005171_absent_coat_pigmentation1.35973568
54MP0004215_abnormal_myocardial_fiber1.35654890
55MP0005623_abnormal_meninges_morphology1.35175445
56MP0005409_darkened_coat_color1.32944941
57MP0002653_abnormal_ependyma_morphology1.30705079
58MP0005253_abnormal_eye_physiology1.30599038
59MP0002557_abnormal_social/conspecific_i1.30416224
60MP0006276_abnormal_autonomic_nervous1.28536578
61MP0004145_abnormal_muscle_electrophysio1.26734306
62MP0003633_abnormal_nervous_system1.26114368
63MP0004811_abnormal_neuron_physiology1.25646260
64MP0003631_nervous_system_phenotype1.24835674
65MP0003632_abnormal_nervous_system1.23944895
66MP0005551_abnormal_eye_electrophysiolog1.23701138
67MP0009780_abnormal_chondrocyte_physiolo1.22773387
68MP0000751_myopathy1.21372250
69MP0010386_abnormal_urinary_bladder1.20036514
70MP0003195_calcinosis1.18909822
71MP0004133_heterotaxia1.16935331
72MP0002102_abnormal_ear_morphology1.16653733
73MP0002152_abnormal_brain_morphology1.16060592
74MP0004858_abnormal_nervous_system1.12716772
75MP0001963_abnormal_hearing_physiology1.11958660
76MP0004147_increased_porphyrin_level1.07868738
77MP0003122_maternal_imprinting1.06177520
78MP0002752_abnormal_somatic_nervous1.05453048
79MP0003879_abnormal_hair_cell1.02746091
80MP0003136_yellow_coat_color1.01585730
81MP0005167_abnormal_blood-brain_barrier1.01264067
82MP0001299_abnormal_eye_distance/0.99724989
83MP0001502_abnormal_circadian_rhythm0.98799308
84MP0009764_decreased_sensitivity_to0.97890202
85MP0000427_abnormal_hair_cycle0.96845407
86MP0005645_abnormal_hypothalamus_physiol0.95964861
87MP0000604_amyloidosis0.95317255
88MP0004134_abnormal_chest_morphology0.95129960
89MP0000462_abnormal_digestive_system0.93989854
90MP0001177_atelectasis0.92905396
91MP0005646_abnormal_pituitary_gland0.92210874
92MP0005410_abnormal_fertilization0.90783422
93MP0006292_abnormal_olfactory_placode0.89656086
94MP0003011_delayed_dark_adaptation0.89118776
95MP0000747_muscle_weakness0.88941089
96MP0008775_abnormal_heart_ventricle0.86499339
97MP0000003_abnormal_adipose_tissue0.86383523
98MP0003938_abnormal_ear_development0.85877433
99MP0002938_white_spotting0.85343181
100MP0003137_abnormal_impulse_conducting0.83754465
101MP0002909_abnormal_adrenal_gland0.83573471
102MP0001348_abnormal_lacrimal_gland0.83301231
103MP0003121_genomic_imprinting0.80964084
104MP0003698_abnormal_male_reproductive0.79200965
105MP0000230_abnormal_systemic_arterial0.79059917
106MP0004085_abnormal_heartbeat0.78895321
107MP0000631_abnormal_neuroendocrine_gland0.76949392
108MP0004043_abnormal_pH_regulation0.76452305
109MP0002234_abnormal_pharynx_morphology0.76399303
110MP0003385_abnormal_body_wall0.73786825
111MP0000026_abnormal_inner_ear0.73746575
112MP0005620_abnormal_muscle_contractility0.72431416
113MP0001984_abnormal_olfaction0.72406668
114MP0003861_abnormal_nervous_system0.72078978
115MP0004484_altered_response_of0.70858308
116MP0004084_abnormal_cardiac_muscle0.69842503
117MP0003119_abnormal_digestive_system0.68204573
118MP0001943_abnormal_respiration0.67170816
119MP0002069_abnormal_eating/drinking_beha0.66813285
120MP0000749_muscle_degeneration0.66560832
121MP0002160_abnormal_reproductive_system0.66380242
122MP0006072_abnormal_retinal_apoptosis0.65888868
123MP0009250_abnormal_appendicular_skeleto0.65302279
124MP0005195_abnormal_posterior_eye0.65078153
125MP0008874_decreased_physiological_sensi0.64488595
126MP0002837_dystrophic_cardiac_calcinosis0.62917789
127MP0004036_abnormal_muscle_relaxation0.60565197
128MP0003283_abnormal_digestive_organ0.60542776
129MP0002090_abnormal_vision0.59232115
130MP0003878_abnormal_ear_physiology0.58491665
131MP0005377_hearing/vestibular/ear_phenot0.58491665
132MP0001664_abnormal_digestion0.58340946

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.43124729
2Neurofibrillary tangles (HP:0002185)5.20217177
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.93135328
4Degeneration of the lateral corticospinal tracts (HP:0002314)4.93135328
5Focal motor seizures (HP:0011153)4.72559905
6Type II lissencephaly (HP:0007260)4.45573314
7Cerebral inclusion bodies (HP:0100314)4.31887894
8Abnormality of the corticospinal tract (HP:0002492)4.14724911
9Supranuclear gaze palsy (HP:0000605)4.03109450
10Hemiplegia (HP:0002301)3.89393004
11Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.71560659
12Focal seizures (HP:0007359)3.66611227
13Cerebellar dysplasia (HP:0007033)3.57335506
14Epileptic encephalopathy (HP:0200134)3.45609827
15Termporal pattern (HP:0011008)3.44120555
16Insidious onset (HP:0003587)3.44120555
17Pancreatic cysts (HP:0001737)3.42894500
18Dysmetria (HP:0001310)3.36550315
19Peripheral hypomyelination (HP:0007182)3.36493539
20Ankle clonus (HP:0011448)3.34951359
21Spastic gait (HP:0002064)3.31861340
22Atonic seizures (HP:0010819)3.26968293
23Congenital stationary night blindness (HP:0007642)3.21220778
24Pancreatic fibrosis (HP:0100732)3.17696274
25Nephronophthisis (HP:0000090)3.15754660
26Abnormality of midbrain morphology (HP:0002418)3.14729463
27Molar tooth sign on MRI (HP:0002419)3.14729463
28Sensory axonal neuropathy (HP:0003390)3.13361727
29Oral leukoplakia (HP:0002745)3.06100103
30Megalencephaly (HP:0001355)3.04408502
31Abnormal drinking behavior (HP:0030082)2.97127643
32Polydipsia (HP:0001959)2.97127643
33Visual hallucinations (HP:0002367)2.91700646
34Intention tremor (HP:0002080)2.85795608
35True hermaphroditism (HP:0010459)2.85415512
36Scanning speech (HP:0002168)2.84462011
37Abnormality of the renal cortex (HP:0011035)2.80550909
38Retinal dysplasia (HP:0007973)2.80415033
39Broad-based gait (HP:0002136)2.75467169
40Action tremor (HP:0002345)2.72283525
41Chronic hepatic failure (HP:0100626)2.70002210
42Abnormality of the renal medulla (HP:0100957)2.69971454
43Parakeratosis (HP:0001036)2.69875049
44Onion bulb formation (HP:0003383)2.69607724
45Calf muscle hypertrophy (HP:0008981)2.68087824
46Progressive cerebellar ataxia (HP:0002073)2.66961589
47Thickened helices (HP:0000391)2.66494115
48Genetic anticipation (HP:0003743)2.65972255
49Lissencephaly (HP:0001339)2.60464459
50Tubular atrophy (HP:0000092)2.55891345
51Pheochromocytoma (HP:0002666)2.55656096
52Anomalous pulmonary venous return (HP:0010772)2.48332162
53Inability to walk (HP:0002540)2.47692941
54Dialeptic seizures (HP:0011146)2.47678219
55Pachygyria (HP:0001302)2.47062344
56Urinary urgency (HP:0000012)2.46784708
57Aplasia involving bones of the upper limbs (HP:0009823)2.46101681
58Aplasia of the phalanges of the hand (HP:0009802)2.46101681
59Aplasia involving bones of the extremities (HP:0009825)2.46101681
60Abnormality of alanine metabolism (HP:0010916)2.45955509
61Hyperalaninemia (HP:0003348)2.45955509
62Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.45955509
63Poor eye contact (HP:0000817)2.45843750
64Absence seizures (HP:0002121)2.45594747
65Muscle hypertrophy of the lower extremities (HP:0008968)2.42526129
66Alacrima (HP:0000522)2.41392575
67Protruding tongue (HP:0010808)2.38995338
68Urinary bladder sphincter dysfunction (HP:0002839)2.38196655
69Lower limb muscle weakness (HP:0007340)2.38059157
70Generalized tonic-clonic seizures (HP:0002069)2.36364468
71Attenuation of retinal blood vessels (HP:0007843)2.33962883
72Dysdiadochokinesis (HP:0002075)2.33469354
73Medial flaring of the eyebrow (HP:0010747)2.32476058
74Gaze-evoked nystagmus (HP:0000640)2.29859799
75Anxiety (HP:0000739)2.28632001
76Akinesia (HP:0002304)2.26917693
77Gait imbalance (HP:0002141)2.23882690
78Hypoplasia of the pons (HP:0012110)2.21212684
79Agitation (HP:0000713)2.19822431
80Cystic liver disease (HP:0006706)2.19714225
81Polyuria (HP:0000103)2.18508124
82Abnormality of the pons (HP:0007361)2.18157397
83Congenital ichthyosiform erythroderma (HP:0007431)2.17839194
84Impaired vibration sensation in the lower limbs (HP:0002166)2.17831385
85Febrile seizures (HP:0002373)2.17779676
86Hyperventilation (HP:0002883)2.17328802
87Cerebral hypomyelination (HP:0006808)2.17160068
88Abnormality of the pulmonary veins (HP:0011718)2.16355880
89Polyphagia (HP:0002591)2.16138365
90Decreased central vision (HP:0007663)2.15827576
91Prolonged QT interval (HP:0001657)2.15055325
92Severe muscular hypotonia (HP:0006829)2.12326141
93Neuroendocrine neoplasm (HP:0100634)2.11803071
94Generalized myoclonic seizures (HP:0002123)2.08041628
95Absent/shortened dynein arms (HP:0200106)2.08038334
96Dynein arm defect of respiratory motile cilia (HP:0012255)2.08038334
97Fetal akinesia sequence (HP:0001989)2.07015319
98Syncope (HP:0001279)2.05731808
99Hemiparesis (HP:0001269)2.05537270
100Impaired social interactions (HP:0000735)2.04189436
101Abnormal social behavior (HP:0012433)2.04189436
102Abnormal eating behavior (HP:0100738)2.03177890
103Bowel incontinence (HP:0002607)2.01487702
104Chorioretinal atrophy (HP:0000533)2.00625762
105Amelogenesis imperfecta (HP:0000705)2.00310856
106Mutism (HP:0002300)2.00107670
107Amblyopia (HP:0000646)1.99986249
108Aplasia/Hypoplasia of the tibia (HP:0005772)1.97387666
109Limb dystonia (HP:0002451)1.96507312
110Progressive inability to walk (HP:0002505)1.96038733
111Slow saccadic eye movements (HP:0000514)1.95814816
112Depression (HP:0000716)1.95253175
113Abolished electroretinogram (ERG) (HP:0000550)1.94961003
114Decreased circulating renin level (HP:0003351)1.94681777
115Truncal ataxia (HP:0002078)1.94569093
116Frequent falls (HP:0002359)1.94517543
117Abnormal auditory evoked potentials (HP:0006958)1.93745376
118Lipid accumulation in hepatocytes (HP:0006561)1.93296867
119Abnormal rod and cone electroretinograms (HP:0008323)1.92557285
120Renal cortical cysts (HP:0000803)1.89241516
121Epileptiform EEG discharges (HP:0011182)1.88312850
122Cerebral hemorrhage (HP:0001342)1.88250671
123Large for gestational age (HP:0001520)1.87993965
124Bundle branch block (HP:0011710)1.87829554
125Keratoconus (HP:0000563)1.87539430
126Increased corneal curvature (HP:0100692)1.87539430
127Left ventricular hypertrophy (HP:0001712)1.87185937
128Hypoplastic pelvis (HP:0008839)1.86781906
129EEG with generalized epileptiform discharges (HP:0011198)1.86414268
130Stomach cancer (HP:0012126)1.86123213
131Decreased lacrimation (HP:0000633)1.85388031
132Abnormal urine output (HP:0012590)1.85176313
133Clumsiness (HP:0002312)1.85035103
134Optic nerve hypoplasia (HP:0000609)1.84508954
135Torticollis (HP:0000473)1.84226004
136Bony spicule pigmentary retinopathy (HP:0007737)1.84093750
137Abnormal large intestine physiology (HP:0012700)1.83873073
138Aplasia/Hypoplasia of the brainstem (HP:0007362)1.83788505
139Hypoplasia of the brainstem (HP:0002365)1.83788505
140Hypsarrhythmia (HP:0002521)1.82945180
141Abnormality of glycolysis (HP:0004366)1.82497155
142Increased serum pyruvate (HP:0003542)1.82497155
143Foot dorsiflexor weakness (HP:0009027)1.81279254
144Clonus (HP:0002169)1.79863478
145Short femoral neck (HP:0100864)1.79422322
146Choreoathetosis (HP:0001266)1.79189697
147Absent septum pellucidum (HP:0001331)1.79085662
148Morphological abnormality of the pyramidal tract (HP:0002062)1.78591750
149Absent speech (HP:0001344)1.78527294
150Sclerocornea (HP:0000647)1.78432026
151Coronal craniosynostosis (HP:0004440)1.78313528
152Fair hair (HP:0002286)1.77546161
153Postural instability (HP:0002172)1.77270699
154Congenital primary aphakia (HP:0007707)1.76992405
155Diplopia (HP:0000651)1.76537555
156Abnormality of binocular vision (HP:0011514)1.76537555
157Hammertoe (HP:0001765)1.76032203
158Decreased motor nerve conduction velocity (HP:0003431)1.74581539
159Abnormality of the septum pellucidum (HP:0007375)1.74255426
160Split foot (HP:0001839)1.73933411
161Pendular nystagmus (HP:0012043)1.73366493
162Anterior segment dysgenesis (HP:0007700)1.73178181
163Increased circulating renin level (HP:0000848)1.73041021
164Neuronal loss in central nervous system (HP:0002529)1.72099108
165Stereotypic behavior (HP:0000733)1.71583421
166Leukodystrophy (HP:0002415)1.70928306
167Widely spaced teeth (HP:0000687)1.70786067
168Excessive salivation (HP:0003781)1.70456266
169Drooling (HP:0002307)1.70456266
170Bulbous nose (HP:0000414)1.70380377
171Abnormality of the foot musculature (HP:0001436)1.70094842
172Buphthalmos (HP:0000557)1.69074966
173Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.68054305
174Abnormal EKG (HP:0003115)1.66899839

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.97820697
2FRK3.78821340
3EPHA43.53191110
4TLK13.38709375
5ZAK2.96695200
6OXSR12.92439496
7MARK12.63125882
8NTRK32.60736689
9MAP3K92.40791506
10PNCK2.26032420
11NTRK12.23645955
12PAK62.23038164
13ADRBK22.16739569
14TNIK2.16201160
15CDK192.13047401
16BMPR1B1.99187945
17CASK1.92275903
18UHMK11.90178133
19ACVR1B1.83269042
20MAPKAPK51.82514722
21PKN11.74786781
22WNK41.72365141
23MAP3K41.69595463
24KSR21.64243785
25MINK11.60520524
26PRPF4B1.59793594
27EPHB11.57850093
28NTRK21.54663390
29BCR1.51756411
30LIMK11.49975093
31WNK11.47645580
32ARAF1.47047036
33MAP4K21.46695496
34PRKD31.46003516
35OBSCN1.44289346
36CDK51.41365938
37WNK31.40233080
38TYRO31.39629125
39GRK11.32937691
40CAMKK21.32658361
41DAPK21.32011964
42INSRR1.30571182
43CAMK2B1.29746927
44TAOK31.25970642
45FGFR21.25957903
46PAK31.22103519
47FGR1.20585940
48ICK1.16389906
49MAP2K71.15099684
50ROCK21.15073337
51CSNK1G31.14114266
52BLK1.12459154
53CSNK1G21.12269928
54MET1.12082120
55PHKG21.09501960
56PHKG11.09501960
57CAMK2A1.07611376
58CDK141.07153346
59NEK61.06735074
60PINK11.05372132
61GRK51.04609523
62MAPK131.03827003
63CSNK1A1L1.02463053
64SGK4941.00538727
65SGK2231.00538727
66CDK151.00193747
67PLK20.99936956
68CAMK2D0.98872594
69IRAK20.97798426
70CDK180.96212615
71MARK20.94211170
72KSR10.93496854
73ADRBK10.92225481
74MAP3K130.88927255
75CDK11A0.88240034
76EPHA30.87326041
77STK110.82955185
78CSNK1G10.81571335
79DDR20.81542420
80DMPK0.81065241
81FES0.80296343
82PDPK10.79047625
83MAP2K40.76553189
84PRKCH0.75786782
85CLK10.74456186
86CAMK2G0.73481874
87SIK20.72927142
88PRKCG0.71288273
89CAMK40.70695291
90SGK20.70658175
91BRAF0.70518091
92PTK2B0.70153066
93NUAK10.69189259
94PRKCE0.68481001
95MAP2K60.68265286
96CAMKK10.66739006
97VRK10.66713371
98DYRK20.66628318
99MAP3K20.64483580
100PBK0.63391283
101MUSK0.62266630
102TXK0.62188949
103FYN0.57909008
104DYRK1A0.57424446
105CAMK1G0.55761416
106PRKAA10.55672237
107RPS6KA50.55388636
108PDK10.55240781
109RAF10.55037735
110LATS20.54992103
111MAPKAPK30.54874161
112CAMK10.54731305
113PRKD10.53939361
114RIPK40.53913630
115STK38L0.53669335
116DAPK30.52594476
117PRKCZ0.51627753
118PRKD20.51113741
119TAOK10.49836968
120RET0.49734337
121MKNK20.49236749
122TESK20.49207291
123PRKCQ0.48416481
124PRKACA0.46571944
125STK380.45519833
126SGK10.45019620
127BMPR20.45008125
128TIE10.44976288
129MAP3K70.44584448
130CAMK1D0.42928865
131PRKG10.41279806
132AKT30.41208108
133PRKAA20.41167051
134PIK3CA0.40664841
135MAP2K20.38579775
136CSNK1D0.38506225
137BMX0.38326044
138PRKCA0.37352015
139PRKCI0.35817686
140ROCK10.35578017
141MAPK120.34838647
142MAP2K10.34693390
143RPS6KA30.34373790
144MAPK150.33649543

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.77889991
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.73175436
3GABAergic synapse_Homo sapiens_hsa047272.42865279
4Glutamatergic synapse_Homo sapiens_hsa047242.38184979
5Synaptic vesicle cycle_Homo sapiens_hsa047212.33261137
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.28240292
7Morphine addiction_Homo sapiens_hsa050322.19645407
8Circadian entrainment_Homo sapiens_hsa047132.16824685
9Steroid biosynthesis_Homo sapiens_hsa001002.13532198
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.97884209
11Olfactory transduction_Homo sapiens_hsa047401.92250498
12Axon guidance_Homo sapiens_hsa043601.92037617
13Long-term potentiation_Homo sapiens_hsa047201.91835557
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.90096052
15Amphetamine addiction_Homo sapiens_hsa050311.86803260
16Salivary secretion_Homo sapiens_hsa049701.82252527
17Dopaminergic synapse_Homo sapiens_hsa047281.81666212
18Long-term depression_Homo sapiens_hsa047301.78166108
19Fatty acid elongation_Homo sapiens_hsa000621.77030426
20Serotonergic synapse_Homo sapiens_hsa047261.71924413
21Cocaine addiction_Homo sapiens_hsa050301.67187391
22Cholinergic synapse_Homo sapiens_hsa047251.66753904
23Gastric acid secretion_Homo sapiens_hsa049711.62308861
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.54629400
25Ether lipid metabolism_Homo sapiens_hsa005651.51736886
26Cardiac muscle contraction_Homo sapiens_hsa042601.49646387
27Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.47392031
28Oxidative phosphorylation_Homo sapiens_hsa001901.45161879
29Insulin secretion_Homo sapiens_hsa049111.38927338
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.37839282
31Oxytocin signaling pathway_Homo sapiens_hsa049211.37775136
32Renin secretion_Homo sapiens_hsa049241.36392653
33Gap junction_Homo sapiens_hsa045401.30245375
34Taste transduction_Homo sapiens_hsa047421.30129120
35Aldosterone synthesis and secretion_Homo sapiens_hsa049251.24633800
36Alzheimers disease_Homo sapiens_hsa050101.23607302
37Collecting duct acid secretion_Homo sapiens_hsa049661.22591611
38ABC transporters_Homo sapiens_hsa020101.21218471
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.20503677
40Calcium signaling pathway_Homo sapiens_hsa040201.17625438
41Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.17521646
42GnRH signaling pathway_Homo sapiens_hsa049121.16468580
43Parkinsons disease_Homo sapiens_hsa050121.15017737
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.13177033
45ErbB signaling pathway_Homo sapiens_hsa040121.12350535
46Tryptophan metabolism_Homo sapiens_hsa003801.10925344
47Vascular smooth muscle contraction_Homo sapiens_hsa042701.10908387
48Renal cell carcinoma_Homo sapiens_hsa052111.10660455
49cAMP signaling pathway_Homo sapiens_hsa040241.09652269
50Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09589433
51Phospholipase D signaling pathway_Homo sapiens_hsa040721.07420594
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.06277500
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.05726983
54Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.04284720
55Melanogenesis_Homo sapiens_hsa049161.03924194
56Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.03069645
57Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.00863288
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.00030799
59Sphingolipid signaling pathway_Homo sapiens_hsa040710.96257117
60Vibrio cholerae infection_Homo sapiens_hsa051100.95487750
61Estrogen signaling pathway_Homo sapiens_hsa049150.94865694
62Selenocompound metabolism_Homo sapiens_hsa004500.94347706
63Systemic lupus erythematosus_Homo sapiens_hsa053220.93984242
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.90670711
65Phototransduction_Homo sapiens_hsa047440.88311748
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87863529
67Nitrogen metabolism_Homo sapiens_hsa009100.87217986
68Dilated cardiomyopathy_Homo sapiens_hsa054140.86305167
69Glioma_Homo sapiens_hsa052140.86279639
70SNARE interactions in vesicular transport_Homo sapiens_hsa041300.85585870
71Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83506623
72Regulation of autophagy_Homo sapiens_hsa041400.83126376
73Ras signaling pathway_Homo sapiens_hsa040140.82166075
74Fatty acid biosynthesis_Homo sapiens_hsa000610.81792842
75Dorso-ventral axis formation_Homo sapiens_hsa043200.80648975
76Tight junction_Homo sapiens_hsa045300.80013081
77Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79109982
78Choline metabolism in cancer_Homo sapiens_hsa052310.78731390
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77923954
80Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.77409936
81Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.75459148
82Sphingolipid metabolism_Homo sapiens_hsa006000.74605059
83Butanoate metabolism_Homo sapiens_hsa006500.73711275
84Pancreatic secretion_Homo sapiens_hsa049720.70506601
85Hedgehog signaling pathway_Homo sapiens_hsa043400.70197274
86Circadian rhythm_Homo sapiens_hsa047100.69495029
87Ovarian steroidogenesis_Homo sapiens_hsa049130.67934377
88Bile secretion_Homo sapiens_hsa049760.67371250
89Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66800516
90Endocytosis_Homo sapiens_hsa041440.66282545
91Glycerolipid metabolism_Homo sapiens_hsa005610.64849252
92Huntingtons disease_Homo sapiens_hsa050160.63838609
93MAPK signaling pathway_Homo sapiens_hsa040100.63231745
94Propanoate metabolism_Homo sapiens_hsa006400.62155874
95Histidine metabolism_Homo sapiens_hsa003400.61852985
96Type II diabetes mellitus_Homo sapiens_hsa049300.61256273
97Prion diseases_Homo sapiens_hsa050200.61183109
98VEGF signaling pathway_Homo sapiens_hsa043700.58025605
99Rap1 signaling pathway_Homo sapiens_hsa040150.57468196
100RNA polymerase_Homo sapiens_hsa030200.57273486
101beta-Alanine metabolism_Homo sapiens_hsa004100.56378001
102Wnt signaling pathway_Homo sapiens_hsa043100.55641724
103Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.51981332
104Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.50935360
105Alcoholism_Homo sapiens_hsa050340.49553136
106Peroxisome_Homo sapiens_hsa041460.49189562
107Regulation of actin cytoskeleton_Homo sapiens_hsa048100.49014056
108Oocyte meiosis_Homo sapiens_hsa041140.48656410
109Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48648146
110Thyroid hormone synthesis_Homo sapiens_hsa049180.47685261
111Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.47088547
112Arachidonic acid metabolism_Homo sapiens_hsa005900.42951046
113Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40378089
114Sulfur relay system_Homo sapiens_hsa041220.40338026
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37891548
116Inositol phosphate metabolism_Homo sapiens_hsa005620.37636959
117Caffeine metabolism_Homo sapiens_hsa002320.37429677
118Sulfur metabolism_Homo sapiens_hsa009200.36615138
119Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36302023
120Glycerophospholipid metabolism_Homo sapiens_hsa005640.34748685
121Primary bile acid biosynthesis_Homo sapiens_hsa001200.34488100
122Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.33945834
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33336284
124Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.33134895
125Arginine and proline metabolism_Homo sapiens_hsa003300.32709010
126Linoleic acid metabolism_Homo sapiens_hsa005910.32672190
127Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30923218

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »