DARS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.23130098
2DNA strand elongation involved in DNA replication (GO:0006271)5.10907017
3DNA strand elongation (GO:0022616)4.84058017
4telomere maintenance via semi-conservative replication (GO:0032201)4.79045696
5DNA replication initiation (GO:0006270)4.69258108
6nucleobase biosynthetic process (GO:0046112)4.66702751
7mitotic metaphase plate congression (GO:0007080)4.65980695
8protein localization to kinetochore (GO:0034501)4.54693913
9pore complex assembly (GO:0046931)4.52254817
10purine nucleobase biosynthetic process (GO:0009113)4.44038536
11CENP-A containing nucleosome assembly (GO:0034080)4.33202974
12chromatin remodeling at centromere (GO:0031055)4.33011112
13IMP biosynthetic process (GO:0006188)4.29794281
14telomere maintenance via recombination (GO:0000722)4.27747593
15folic acid-containing compound biosynthetic process (GO:0009396)4.27725669
16mitotic recombination (GO:0006312)4.19393572
17metaphase plate congression (GO:0051310)4.19025631
18regulation of translational fidelity (GO:0006450)4.14449812
19mitotic sister chromatid cohesion (GO:0007064)4.12546822
20maturation of SSU-rRNA (GO:0030490)4.04843468
21mitotic chromosome condensation (GO:0007076)4.04657016
22attachment of spindle microtubules to kinetochore (GO:0008608)4.04064794
23ribosomal small subunit assembly (GO:0000028)4.01828090
24DNA replication checkpoint (GO:0000076)3.97911042
25telomere maintenance via telomere lengthening (GO:0010833)3.96335249
26kinetochore organization (GO:0051383)3.95051033
27regulation of spindle organization (GO:0090224)3.89918174
28mitotic nuclear envelope disassembly (GO:0007077)3.89354915
29protein localization to chromosome, centromeric region (GO:0071459)3.87289534
30mitotic sister chromatid segregation (GO:0000070)3.85139609
31DNA topological change (GO:0006265)3.84832670
32DNA replication-independent nucleosome organization (GO:0034724)3.77465320
33DNA replication-independent nucleosome assembly (GO:0006336)3.77465320
34formation of translation preinitiation complex (GO:0001731)3.76784708
35DNA replication-dependent nucleosome assembly (GO:0006335)3.76429859
36DNA replication-dependent nucleosome organization (GO:0034723)3.76429859
37regulation of centriole replication (GO:0046599)3.74662298
38nucleotide-excision repair, DNA gap filling (GO:0006297)3.71823776
39IMP metabolic process (GO:0046040)3.70098515
40establishment of chromosome localization (GO:0051303)3.68803628
41DNA deamination (GO:0045006)3.63353377
42protein complex localization (GO:0031503)3.59663274
43nuclear envelope disassembly (GO:0051081)3.56580212
44membrane disassembly (GO:0030397)3.56580212
45sister chromatid segregation (GO:0000819)3.55938662
46positive regulation of chromosome segregation (GO:0051984)3.55254128
47histone exchange (GO:0043486)3.53431045
48DNA ligation (GO:0006266)3.51324212
49chromosome condensation (GO:0030261)3.51125944
50folic acid metabolic process (GO:0046655)3.49270050
51ribosomal large subunit biogenesis (GO:0042273)3.48892072
52kinetochore assembly (GO:0051382)3.48645014
53meiotic chromosome segregation (GO:0045132)3.46469664
54chromosome segregation (GO:0007059)3.45649947
55non-recombinational repair (GO:0000726)3.44481000
56double-strand break repair via nonhomologous end joining (GO:0006303)3.44481000
57ribosome assembly (GO:0042255)3.44263194
58nuclear pore organization (GO:0006999)3.42984416
59ribosome biogenesis (GO:0042254)3.36100698
60regulation of mitotic spindle organization (GO:0060236)3.31354022
61DNA geometric change (GO:0032392)3.30506066
62DNA duplex unwinding (GO:0032508)3.30356557
63regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.28962407
64proteasome assembly (GO:0043248)3.28841044
65nucleobase-containing small molecule interconversion (GO:0015949)3.27793215
66regulation of centrosome cycle (GO:0046605)3.27108180
67anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.26381186
68transcription-coupled nucleotide-excision repair (GO:0006283)3.25715430
69rRNA modification (GO:0000154)3.23439818
70nuclear envelope organization (GO:0006998)3.22552915
71regulation of sister chromatid segregation (GO:0033045)3.21054471
72regulation of mitotic sister chromatid separation (GO:0010965)3.21054471
73regulation of mitotic sister chromatid segregation (GO:0033047)3.21054471
74regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.20281467
75spindle checkpoint (GO:0031577)3.19750720
76ribonucleoprotein complex biogenesis (GO:0022613)3.19474275
77pseudouridine synthesis (GO:0001522)3.16555029
78cellular protein complex localization (GO:0034629)3.16249623
79positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.16166259
80DNA packaging (GO:0006323)3.15376725
81somatic diversification of immune receptors via somatic mutation (GO:0002566)3.13565596
82somatic hypermutation of immunoglobulin genes (GO:0016446)3.13565596
83negative regulation of chromosome segregation (GO:0051985)3.12800872
84* tRNA aminoacylation for protein translation (GO:0006418)3.12656170
85negative regulation of mitotic sister chromatid separation (GO:2000816)3.11316754
86negative regulation of mitotic sister chromatid segregation (GO:0033048)3.11316754
87negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.11316754
88negative regulation of sister chromatid segregation (GO:0033046)3.11316754
89telomere organization (GO:0032200)3.11302205
90establishment of integrated proviral latency (GO:0075713)3.11160364
91spindle assembly checkpoint (GO:0071173)3.10745158
92telomere maintenance (GO:0000723)3.10712375
93negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.10684994
94spliceosomal snRNP assembly (GO:0000387)3.09549977
95positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.09310715
96positive regulation of mitotic sister chromatid separation (GO:1901970)3.09310715
97positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.09310715
98regulation of double-strand break repair via homologous recombination (GO:0010569)3.08925895
99regulation of mitotic metaphase/anaphase transition (GO:0030071)3.08213488
100L-serine metabolic process (GO:0006563)3.08149212
101glycine metabolic process (GO:0006544)3.08038926
102* amino acid activation (GO:0043038)3.07494801
103* tRNA aminoacylation (GO:0043039)3.07494801
104rRNA processing (GO:0006364)3.06612802
105regulation of chromosome segregation (GO:0051983)3.05971119
106establishment of viral latency (GO:0019043)3.05261625
107mitotic spindle assembly checkpoint (GO:0007094)3.04880286
108regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.04787535
109translational termination (GO:0006415)3.02648278
110viral mRNA export from host cell nucleus (GO:0046784)3.02174262
111negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.02074996
112regulation of sister chromatid cohesion (GO:0007063)3.02069023
113tetrahydrofolate metabolic process (GO:0046653)3.01681093
114viral transcription (GO:0019083)3.01084333
115mismatch repair (GO:0006298)3.00362363
116negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.00299646
117regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.99770797
118pteridine-containing compound biosynthetic process (GO:0042559)2.97975399
119chromatin assembly or disassembly (GO:0006333)2.97891754
120mitotic spindle checkpoint (GO:0071174)2.97507353
121rRNA metabolic process (GO:0016072)2.96593471
122proline biosynthetic process (GO:0006561)2.96379538
123G1/S transition of mitotic cell cycle (GO:0000082)2.96171113
124cell cycle G1/S phase transition (GO:0044843)2.96171113
125nuclear pore complex assembly (GO:0051292)2.91831562
126mitotic cell cycle (GO:0000278)2.91059804
127protein localization to chromosome (GO:0034502)2.91049369
128deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.90296745
129DNA conformation change (GO:0071103)2.90256775

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.99041408
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.65929795
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.29651744
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.97298752
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.69508286
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.61503307
7* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.28959918
8* EST1_17652178_ChIP-ChIP_JURKAT_Human3.00978016
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88654480
10MYC_19079543_ChIP-ChIP_MESCs_Mouse2.85602669
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.85043937
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.84328026
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.71212902
14* ETS1_20019798_ChIP-Seq_JURKAT_Human2.70655252
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.67093536
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.46333170
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.43431441
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.33470482
19AR_21909140_ChIP-Seq_LNCAP_Human2.31100223
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.25079229
21XRN2_22483619_ChIP-Seq_HELA_Human2.24412566
22VDR_23849224_ChIP-Seq_CD4+_Human2.19720147
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.08184448
24E2F1_21310950_ChIP-Seq_MCF-7_Human2.04378378
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.04142663
26FOXP3_21729870_ChIP-Seq_TREG_Human2.01646742
27* DCP1A_22483619_ChIP-Seq_HELA_Human2.01345952
28* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.98358115
29THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92236962
30MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.87702552
31* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.86543885
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84198347
33E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.83560414
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81866013
35GABP_19822575_ChIP-Seq_HepG2_Human1.77990582
36* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.76701171
37KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.71994726
38* TTF2_22483619_ChIP-Seq_HELA_Human1.71355668
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.70883920
40* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67909824
41* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.65711734
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.62745597
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.62037024
44* SRF_21415370_ChIP-Seq_HL-1_Mouse1.61574755
45* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.60303432
46* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.60278044
47PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.56757785
48* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.54494440
49* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53927035
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.53924341
51RBPJ_22232070_ChIP-Seq_NCS_Mouse1.52853420
52SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.52525346
53ELK1_19687146_ChIP-ChIP_HELA_Human1.48735689
54CIITA_25753668_ChIP-Seq_RAJI_Human1.48528051
55KDM5A_27292631_Chip-Seq_BREAST_Human1.40990345
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.35150578
57PADI4_21655091_ChIP-ChIP_MCF-7_Human1.33492932
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.33365521
59SALL1_21062744_ChIP-ChIP_HESCs_Human1.32213044
60EGR1_19374776_ChIP-ChIP_THP-1_Human1.30113037
61PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28853951
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27698590
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26582736
64ZNF263_19887448_ChIP-Seq_K562_Human1.26250194
65* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25212122
66* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.24509435
67STAT3_1855785_ChIP-Seq_MESCs_Mouse1.23144675
68* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.22348204
69* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19575468
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.18506276
71* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.17162519
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.14784739
73MYC_22102868_ChIP-Seq_BL_Human1.14542808
74CHD1_26751641_Chip-Seq_LNCaP_Human1.12436116
75SOX17_20123909_ChIP-Seq_XEN_Mouse1.09774269
76SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.09197727
77* TFEB_21752829_ChIP-Seq_HELA_Human1.08428275
78KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06208289
79SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.01438541
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.00989061
81MYC_18940864_ChIP-ChIP_HL60_Human1.00976979
82ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00648002
83* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00412148
84CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.99725316
85TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.97764854
86* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97487286
87ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.96979404
88* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95697706
89ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94433211
90HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92629235
91* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91691809
92PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.91040434
93NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.89928606
94GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89765658
95NOTCH1_21737748_ChIP-Seq_TLL_Human0.89294749
96* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88506372
97* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.87968066
98DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87077032
99DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.84643351
100* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.84539738
101SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.81760371
102TBX5_21415370_ChIP-Seq_HL-1_Mouse0.79682285
103TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.79461445
104* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.78288577
105TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.77634753
106EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.77059119
107* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.76984208
108EGR1_23403033_ChIP-Seq_LIVER_Mouse0.74759356
109CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73663961
110TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.73236741
111SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.72946131
112ESR1_15608294_ChIP-ChIP_MCF-7_Human0.72657983
113SPI1_23547873_ChIP-Seq_NB4_Human0.72509815
114IRF1_19129219_ChIP-ChIP_H3396_Human0.70515678
115NANOG_21062744_ChIP-ChIP_HESCs_Human0.68435560

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.65056935
2MP0010094_abnormal_chromosome_stability5.39661084
3MP0003111_abnormal_nucleus_morphology4.93320545
4MP0004957_abnormal_blastocyst_morpholog4.57775873
5MP0003077_abnormal_cell_cycle4.32198597
6MP0008057_abnormal_DNA_replication4.19797631
7MP0008058_abnormal_DNA_repair3.68480470
8MP0003806_abnormal_nucleotide_metabolis3.06147561
9MP0008007_abnormal_cellular_replicative2.88319546
10MP0008932_abnormal_embryonic_tissue2.62149275
11MP0002396_abnormal_hematopoietic_system2.60056519
12MP0001730_embryonic_growth_arrest2.40884046
13MP0008877_abnormal_DNA_methylation2.29257165
14MP0003123_paternal_imprinting2.24195733
15MP0002877_abnormal_melanocyte_morpholog2.20373716
16MP0000350_abnormal_cell_proliferation2.20299586
17MP0004233_abnormal_muscle_weight2.08582717
18MP0003941_abnormal_skin_development2.03567466
19MP0010352_gastrointestinal_tract_polyps1.99997515
20MP0010307_abnormal_tumor_latency1.98308625
21MP0004147_increased_porphyrin_level1.91706565
22MP0006036_abnormal_mitochondrial_physio1.85302406
23MP0003718_maternal_effect1.78108566
24MP0003786_premature_aging1.76278395
25MP0005380_embryogenesis_phenotype1.66784635
26MP0001672_abnormal_embryogenesis/_devel1.66784635
27MP0001697_abnormal_embryo_size1.65134668
28MP0000490_abnormal_crypts_of1.64044444
29MP0003186_abnormal_redox_activity1.62252095
30MP0002080_prenatal_lethality1.59633008
31MP0009697_abnormal_copulation1.57346236
32MP0005360_urolithiasis1.54348574
33MP0003984_embryonic_growth_retardation1.53523199
34MP0002088_abnormal_embryonic_growth/wei1.49783455
35MP0002139_abnormal_hepatobiliary_system1.48903800
36MP0000313_abnormal_cell_death1.44573999
37MP0002019_abnormal_tumor_incidence1.43962701
38MP0001764_abnormal_homeostasis1.41173586
39MP0005076_abnormal_cell_differentiation1.39618262
40MP0005085_abnormal_gallbladder_physiolo1.39247565
41MP0003705_abnormal_hypodermis_morpholog1.39231993
42MP0005365_abnormal_bile_salt1.36888795
43MP0004185_abnormal_adipocyte_glucose1.35315453
44MP0005408_hypopigmentation1.30013927
45MP0000537_abnormal_urethra_morphology1.29024521
46MP0006035_abnormal_mitochondrial_morpho1.27197707
47MP0003656_abnormal_erythrocyte_physiolo1.25846185
48MP0009840_abnormal_foam_cell1.24057174
49MP0002086_abnormal_extraembryonic_tissu1.22599844
50MP0003567_abnormal_fetal_cardiomyocyte1.20706601
51MP0009672_abnormal_birth_weight1.20292325
52MP0004197_abnormal_fetal_growth/weight/1.19704377
53MP0002210_abnormal_sex_determination1.19524025
54MP0001545_abnormal_hematopoietic_system1.19178830
55MP0005397_hematopoietic_system_phenotyp1.19178830
56MP0002085_abnormal_embryonic_tissue1.17227166
57MP0006054_spinal_hemorrhage1.16513473
58MP0005266_abnormal_metabolism1.14327384
59MP0005451_abnormal_body_composition1.14187141
60MP0005501_abnormal_skin_physiology1.14035288
61MP0002009_preneoplasia1.13070184
62MP0004782_abnormal_surfactant_physiolog1.12673815
63MP0003221_abnormal_cardiomyocyte_apopto1.10818720
64MP0001145_abnormal_male_reproductive1.10430507
65MP0004808_abnormal_hematopoietic_stem1.10358765
66MP0001346_abnormal_lacrimal_gland1.09497628
67MP0003937_abnormal_limbs/digits/tail_de1.06154369
68MP0002084_abnormal_developmental_patter1.05330575
69MP0002796_impaired_skin_barrier1.05116892
70MP0003890_abnormal_embryonic-extraembry1.04567235
71MP0002697_abnormal_eye_size1.00044600
72MP0000358_abnormal_cell_content/0.97285170
73MP0001929_abnormal_gametogenesis0.96975097
74MP0008875_abnormal_xenobiotic_pharmacok0.94777237
75MP0000689_abnormal_spleen_morphology0.94771843
76MP0001853_heart_inflammation0.94186190
77MP0000653_abnormal_sex_gland0.93927467
78MP0002132_abnormal_respiratory_system0.93140311
79MP0002722_abnormal_immune_system0.92874310
80MP0003566_abnormal_cell_adhesion0.91931541
81MP0010030_abnormal_orbit_morphology0.91321715
82MP0005332_abnormal_amino_acid0.89599963
83MP0002398_abnormal_bone_marrow0.86144424
84MP0000598_abnormal_liver_morphology0.83429972
85MP0000627_abnormal_mammary_gland0.83278373
86MP0001881_abnormal_mammary_gland0.82349214
87MP0005319_abnormal_enzyme/_coenzyme0.82013023
88MP0005623_abnormal_meninges_morphology0.81511169
89MP0009053_abnormal_anal_canal0.81476387
90MP0000703_abnormal_thymus_morphology0.81081355
91MP0000579_abnormal_nail_morphology0.80115289
92MP0000858_altered_metastatic_potential0.80028372
93MP0002160_abnormal_reproductive_system0.79699755
94MP0004272_abnormal_basement_membrane0.77449528
95MP0005376_homeostasis/metabolism_phenot0.76876963
96MP0002429_abnormal_blood_cell0.73597261
97MP0009333_abnormal_splenocyte_physiolog0.70454437
98MP0000609_abnormal_liver_physiology0.69125062
99MP0001216_abnormal_epidermal_layer0.68618131
100MP0005384_cellular_phenotype0.67377416
101MP0001119_abnormal_female_reproductive0.65928800
102MP0002060_abnormal_skin_morphology0.65177436
103MP0000467_abnormal_esophagus_morphology0.63798084
104MP0001286_abnormal_eye_development0.63781883
105MP0001661_extended_life_span0.63706834
106MP0003943_abnormal_hepatobiliary_system0.63647080
107MP0003950_abnormal_plasma_membrane0.63095208
108MP0003699_abnormal_female_reproductive0.62957804
109MP0001915_intracranial_hemorrhage0.62487627
110MP0001293_anophthalmia0.62101555
111MP0005389_reproductive_system_phenotype0.61055674
112MP0002098_abnormal_vibrissa_morphology0.60858843
113MP0009703_decreased_birth_body0.60585893
114MP0010329_abnormal_lipoprotein_level0.60306948
115MP0004133_heterotaxia0.59565163
116MP0004264_abnormal_extraembryonic_tissu0.59373347
117MP0002938_white_spotting0.59091429
118MP0002092_abnormal_eye_morphology0.58910667
119MP0005621_abnormal_cell_physiology0.58411176
120MP0003121_genomic_imprinting0.58353520
121MP0005395_other_phenotype0.58126346
122MP0002269_muscular_atrophy0.57630824
123MP0003763_abnormal_thymus_physiology0.56425476
124MP0003385_abnormal_body_wall0.56122883
125MP0001727_abnormal_embryo_implantation0.55899730
126MP0001849_ear_inflammation0.55620183
127MP0003315_abnormal_perineum_morphology0.55084654
128MP0000428_abnormal_craniofacial_morphol0.54841219
129MP0000377_abnormal_hair_follicle0.54387603
130MP0009379_abnormal_foot_pigmentation0.53603384
131MP0010234_abnormal_vibrissa_follicle0.52810011
132MP0003115_abnormal_respiratory_system0.52593290
133MP0003935_abnormal_craniofacial_develop0.52575484
134MP0000477_abnormal_intestine_morphology0.52545098
135MP0005330_cardiomyopathy0.52517465
136MP0005220_abnormal_exocrine_pancreas0.51716163
137MP0001186_pigmentation_phenotype0.51204828
138MP0002111_abnormal_tail_morphology0.50866234
139MP0004084_abnormal_cardiac_muscle0.50672448
140MP0004215_abnormal_myocardial_fiber0.49683689
141MP0000716_abnormal_immune_system0.49511914
142MP0008873_increased_physiological_sensi0.48974877

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.48988997
2Reticulocytopenia (HP:0001896)4.44762693
3Birth length less than 3rd percentile (HP:0003561)4.38774494
4Oral leukoplakia (HP:0002745)4.13459724
5Chromosomal breakage induced by crosslinking agents (HP:0003221)4.13106695
6Abnormality of pyrimidine metabolism (HP:0004353)3.88315435
7Abnormality of the preputium (HP:0100587)3.36461685
8Abnormality of chromosome stability (HP:0003220)3.33115263
9Colon cancer (HP:0003003)3.33001974
10Abnormality of cells of the erythroid lineage (HP:0012130)3.23352161
11Abnormal number of erythroid precursors (HP:0012131)3.21061113
12Medulloblastoma (HP:0002885)3.10620537
13Agnosia (HP:0010524)3.10432779
14Cerebral hypomyelination (HP:0006808)3.06727092
15Abnormality of glycolysis (HP:0004366)3.06223193
16Increased serum pyruvate (HP:0003542)3.06223193
17Hypobetalipoproteinemia (HP:0003563)3.05768369
18Meckel diverticulum (HP:0002245)3.05661523
19Absent thumb (HP:0009777)3.03267635
20Nephroblastoma (Wilms tumor) (HP:0002667)2.95481380
21Increased nuchal translucency (HP:0010880)2.92505282
22Duplicated collecting system (HP:0000081)2.87731962
23Abnormality of the ileum (HP:0001549)2.87445339
24Impulsivity (HP:0100710)2.84886471
25Breast hypoplasia (HP:0003187)2.84502937
26Increased serum lactate (HP:0002151)2.84446599
27Aplastic anemia (HP:0001915)2.84017587
28Ependymoma (HP:0002888)2.78909852
29Aplasia/Hypoplasia of the uvula (HP:0010293)2.78623234
30Abnormality of the heme biosynthetic pathway (HP:0010472)2.77624353
31Embryonal renal neoplasm (HP:0011794)2.74378582
32Bone marrow hypocellularity (HP:0005528)2.68409015
33Macrocytic anemia (HP:0001972)2.67714981
34Carpal bone hypoplasia (HP:0001498)2.67487561
35Progressive muscle weakness (HP:0003323)2.65301965
36Hepatic necrosis (HP:0002605)2.64727766
37Rhabdomyosarcoma (HP:0002859)2.64510910
38Myelodysplasia (HP:0002863)2.63230182
39Duodenal stenosis (HP:0100867)2.63152154
40Small intestinal stenosis (HP:0012848)2.63152154
41Hepatocellular necrosis (HP:0001404)2.59100857
42Rough bone trabeculation (HP:0100670)2.55059822
43Pancytopenia (HP:0001876)2.52865533
44Megaloblastic anemia (HP:0001889)2.52296473
45Abnormality of the fetal cardiovascular system (HP:0010948)2.51361088
46Abnormal umbilical cord blood vessels (HP:0011403)2.51361088
47Single umbilical artery (HP:0001195)2.51361088
48Abnormality of the renal collecting system (HP:0004742)2.50559040
49Pallor (HP:0000980)2.49957946
50Microvesicular hepatic steatosis (HP:0001414)2.49128787
51Abnormality of the umbilical cord (HP:0010881)2.48629183
52Multiple enchondromatosis (HP:0005701)2.46911892
53Patellar aplasia (HP:0006443)2.46080801
54Absent radius (HP:0003974)2.45963617
55Aplasia/Hypoplasia of the sacrum (HP:0008517)2.45301005
56Sloping forehead (HP:0000340)2.44303631
57Cellular immunodeficiency (HP:0005374)2.43591817
58Increased CSF lactate (HP:0002490)2.43342530
59Nausea (HP:0002018)2.42859701
60Abnormality of reticulocytes (HP:0004312)2.41154185
61Abnormality of methionine metabolism (HP:0010901)2.40824531
62Deep philtrum (HP:0002002)2.40463293
63Abnormality of the labia minora (HP:0012880)2.39585673
64Hyperglycinemia (HP:0002154)2.39028605
65Progressive external ophthalmoplegia (HP:0000590)2.32718706
66Cortical dysplasia (HP:0002539)2.32070604
67Horseshoe kidney (HP:0000085)2.31046238
68Abnormal lung lobation (HP:0002101)2.29383530
69Septate vagina (HP:0001153)2.28494316
70Reduced antithrombin III activity (HP:0001976)2.27001300
71Abnormality of DNA repair (HP:0003254)2.26839485
72Aplasia/Hypoplasia of the patella (HP:0006498)2.26182388
73Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.25111421
74Decreased activity of mitochondrial respiratory chain (HP:0008972)2.25111421
75Overlapping toe (HP:0001845)2.24955953
76Abnormality of monocarboxylic acid metabolism (HP:0010996)2.24860279
77Premature graying of hair (HP:0002216)2.24009026
78Aplasia involving forearm bones (HP:0009822)2.23812404
79Absent forearm bone (HP:0003953)2.23812404
80Neoplasm of the pancreas (HP:0002894)2.23035897
81Proximal placement of thumb (HP:0009623)2.20870298
82Abnormality of the duodenum (HP:0002246)2.20729791
83Neoplasm of the colon (HP:0100273)2.20272170
84Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.19662109
85Abnormality of alanine metabolism (HP:0010916)2.19662109
86Hyperalaninemia (HP:0003348)2.19662109
87Deviation of the thumb (HP:0009603)2.18473136
88Hyperammonemia (HP:0001987)2.18119151
89Abnormality of serum amino acid levels (HP:0003112)2.16090806
90Hyperglycinuria (HP:0003108)2.14673120
91Abnormal gallbladder physiology (HP:0012438)2.14320771
92Cholecystitis (HP:0001082)2.14320771
93Degeneration of anterior horn cells (HP:0002398)2.12104906
94Abnormality of the anterior horn cell (HP:0006802)2.12104906
95Abnormality of serine family amino acid metabolism (HP:0010894)2.10947287
96Abnormality of glycine metabolism (HP:0010895)2.10947287
97Mitochondrial inheritance (HP:0001427)2.07920257
98Squamous cell carcinoma (HP:0002860)2.07348849
99Trismus (HP:0000211)2.06806019
10011 pairs of ribs (HP:0000878)2.06073706
101Abnormalities of placenta or umbilical cord (HP:0001194)2.05881706
102Choanal atresia (HP:0000453)2.05456522
103Ankyloglossia (HP:0010296)2.03770408
104Ectopic kidney (HP:0000086)2.03629852
105Basal cell carcinoma (HP:0002671)2.03261857
106Selective tooth agenesis (HP:0001592)2.03137988
107Spastic diplegia (HP:0001264)2.03072916
108Cerebral edema (HP:0002181)2.02382812
109Lactic acidosis (HP:0003128)2.00527948
110Thrombocytosis (HP:0001894)1.99290770
111CNS demyelination (HP:0007305)1.99092012
112Acute encephalopathy (HP:0006846)1.97212428
113Secondary amenorrhea (HP:0000869)1.97064547
114Triphalangeal thumb (HP:0001199)1.96415396
115Hypoplasia of the capital femoral epiphysis (HP:0003090)1.95460286
116Glioma (HP:0009733)1.95225853
117Cafe-au-lait spot (HP:0000957)1.94370609
118Abnormality of the carotid arteries (HP:0005344)1.92365673
119CNS hypomyelination (HP:0003429)1.91970665
120Tracheoesophageal fistula (HP:0002575)1.90941472
121Astrocytoma (HP:0009592)1.90771201
122Abnormality of the astrocytes (HP:0100707)1.90771201
123Acute necrotizing encephalopathy (HP:0006965)1.90202474
124Intrahepatic cholestasis (HP:0001406)1.90133363
125Cutaneous melanoma (HP:0012056)1.89969284
126Ureteral duplication (HP:0000073)1.89838753
127Microglossia (HP:0000171)1.89188627
128Abnormal mitochondria in muscle tissue (HP:0008316)1.88881530
129Microretrognathia (HP:0000308)1.88664638
130Type I transferrin isoform profile (HP:0003642)1.86737888
131Lipid accumulation in hepatocytes (HP:0006561)1.86722085
132Volvulus (HP:0002580)1.81521475
133Arteriovenous malformation (HP:0100026)1.81485170
134Premature ovarian failure (HP:0008209)1.80235043
135Embryonal neoplasm (HP:0002898)1.78957895
136Missing ribs (HP:0000921)1.77922394
137Asymmetry of the thorax (HP:0001555)1.74508674
138Clubbing of toes (HP:0100760)1.73105075
139Abnormality of chromosome segregation (HP:0002916)1.72380321
140Short thumb (HP:0009778)1.70802352
141Facial cleft (HP:0002006)1.70425542
142Abnormality of sulfur amino acid metabolism (HP:0004339)1.68451849
143Breast carcinoma (HP:0003002)1.67735429
144Duplication of thumb phalanx (HP:0009942)1.66859279
145Poikiloderma (HP:0001029)1.65207831
146Uterine leiomyosarcoma (HP:0002891)1.64837462
147Leiomyosarcoma (HP:0100243)1.64837462
148Insidious onset (HP:0003587)1.62682341
149Termporal pattern (HP:0011008)1.62682341
150Ragged-red muscle fibers (HP:0003200)1.61035920
151Nonimmune hydrops fetalis (HP:0001790)1.59994872
152Uterine neoplasm (HP:0010784)1.59041230
153Abnormality of cochlea (HP:0000375)1.57821032
154Abnormality of homocysteine metabolism (HP:0010919)1.57400615

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.20481139
2WEE14.84710539
3CDC74.28497597
4NEK13.01229559
5EIF2AK12.90025174
6BRSK22.77741314
7NEK22.71993942
8STK162.56939825
9TSSK62.51352012
10TTK2.42878383
11ACVR1B2.25601024
12SRPK12.23819820
13VRK22.18158234
14PLK12.14662196
15TAF12.03835342
16SMG12.02009523
17TLK11.97683173
18NME21.88156826
19VRK11.86006539
20BCKDK1.84003382
21BRSK11.83086714
22PLK31.78986784
23ATR1.78396168
24AURKB1.76411394
25CCNB11.69903095
26PLK41.65045800
27DYRK31.57043605
28PASK1.54073043
29CDK71.53044201
30MKNK11.51611451
31EIF2AK31.48472593
32RPS6KA41.45028897
33FLT31.43401826
34TRIM281.42175329
35AURKA1.36142033
36BRD41.33448759
37MAP3K81.33048889
38MST1R1.32401523
39CDK41.32148780
40CHEK21.31593783
41PBK1.26978660
42TGFBR11.25237076
43STK41.23968861
44RPS6KB21.23774391
45STK101.23758610
46CHEK11.19359765
47IRAK31.12702996
48PDK41.08913554
49PDK31.08913554
50EPHA21.06988094
51ICK1.05504758
52SCYL21.02479047
53MST40.97983682
54TRIB30.96682232
55MELK0.95434821
56ERBB40.92818776
57ZAK0.91340974
58ATM0.83836571
59TESK20.83421204
60PKN20.83298699
61TEC0.82750964
62LATS10.81897921
63BRAF0.81465607
64NEK90.80446658
65MKNK20.79735520
66EIF2AK20.78557962
67CDK20.76968167
68CDK120.76879582
69STK30.73574123
70PAK40.71746165
71CSNK2A20.70987029
72CSNK2A10.70414495
73CDK60.66085425
74PDK20.65413410
75EEF2K0.64971800
76MET0.64462336
77LMTK20.64435531
78CDK10.63843631
79MAP3K100.61281778
80CDK80.59736525
81RPS6KA50.54880163
82MAP2K30.54316969
83TIE10.54296324
84LATS20.54294436
85PAK10.53727113
86NUAK10.52748393
87MTOR0.51958022
88PIM10.51611651
89CDK90.50365746
90CLK10.49676876
91ALK0.48362403
92BTK0.46761047
93AKT20.45145666
94MAP4K10.43785597
95CAMK1D0.40514388
96GRK60.39792288
97KDR0.39750467
98PRKCI0.39273662
99KSR20.38584130
100MAPK110.38109283
101CAMK1G0.36703408
102MAP3K90.35847449
103PIM20.35393186
104SIK30.35062402
105PNCK0.32522592
106KSR10.30869470
107PRKDC0.29781051
108CDK180.28475055
109MAPKAPK50.27335952
110NEK60.27047068
111FGFR10.26904500
112ABL20.26851227
113KIT0.26828726
114MAPK140.25598900
115CSNK1E0.25553809
116DAPK10.25036579
117CDK150.24934538
118CDK30.24721812
119NME10.24540532
120STK38L0.22147088
121CDK11A0.22101624
122LRRK20.21965456
123RAF10.21459385
124CSF1R0.19667662
125ILK0.19277626
126FRK0.17547974
127LYN0.16963500
128CSNK1D0.16331023
129MAP2K60.15350536
130RPS6KB10.15035669
131AKT30.14882495
132IRAK40.14596496

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.86629329
2Mismatch repair_Homo sapiens_hsa034304.37474351
3Proteasome_Homo sapiens_hsa030503.17433019
4One carbon pool by folate_Homo sapiens_hsa006703.13351974
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.12021792
6Homologous recombination_Homo sapiens_hsa034403.07648099
7Base excision repair_Homo sapiens_hsa034102.94361066
8RNA polymerase_Homo sapiens_hsa030202.83913777
9Ribosome_Homo sapiens_hsa030102.83194636
10Spliceosome_Homo sapiens_hsa030402.76201785
11Nucleotide excision repair_Homo sapiens_hsa034202.74878598
12* Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.71129091
13RNA transport_Homo sapiens_hsa030132.58741689
14Pyrimidine metabolism_Homo sapiens_hsa002402.39008708
15Cell cycle_Homo sapiens_hsa041102.31510783
16Fanconi anemia pathway_Homo sapiens_hsa034602.04587867
17Non-homologous end-joining_Homo sapiens_hsa034501.91093945
18RNA degradation_Homo sapiens_hsa030181.59282733
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.59128977
20Biosynthesis of amino acids_Homo sapiens_hsa012301.51822444
212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49063458
22Cysteine and methionine metabolism_Homo sapiens_hsa002701.44333507
23Basal transcription factors_Homo sapiens_hsa030221.43387287
24Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.42612120
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.41396029
26Systemic lupus erythematosus_Homo sapiens_hsa053221.40027147
27Drug metabolism - other enzymes_Homo sapiens_hsa009831.37189006
28Carbon metabolism_Homo sapiens_hsa012001.35071003
29mRNA surveillance pathway_Homo sapiens_hsa030151.27998259
30Folate biosynthesis_Homo sapiens_hsa007901.26313596
31Vitamin B6 metabolism_Homo sapiens_hsa007501.25395025
32Selenocompound metabolism_Homo sapiens_hsa004501.24369959
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.24227542
34Purine metabolism_Homo sapiens_hsa002301.23657418
35Pentose phosphate pathway_Homo sapiens_hsa000301.20523535
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17112518
37p53 signaling pathway_Homo sapiens_hsa041151.14903167
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.07813316
39Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.06643804
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.03751021
41Sulfur relay system_Homo sapiens_hsa041220.97910405
42Propanoate metabolism_Homo sapiens_hsa006400.94654415
43Pyruvate metabolism_Homo sapiens_hsa006200.89631446
44Steroid biosynthesis_Homo sapiens_hsa001000.84820979
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82402520
46Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.81305976
47Fatty acid degradation_Homo sapiens_hsa000710.79623499
48Glutathione metabolism_Homo sapiens_hsa004800.77865966
49Epstein-Barr virus infection_Homo sapiens_hsa051690.76459508
50Parkinsons disease_Homo sapiens_hsa050120.75815969
51Oocyte meiosis_Homo sapiens_hsa041140.75720870
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.72706921
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.72214497
54Huntingtons disease_Homo sapiens_hsa050160.71790054
55Primary bile acid biosynthesis_Homo sapiens_hsa001200.70077797
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65214850
57Fructose and mannose metabolism_Homo sapiens_hsa000510.61712150
58Chronic myeloid leukemia_Homo sapiens_hsa052200.61538461
59Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61182509
60Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60752207
61MicroRNAs in cancer_Homo sapiens_hsa052060.60106106
62Bladder cancer_Homo sapiens_hsa052190.58116575
63beta-Alanine metabolism_Homo sapiens_hsa004100.57924691
64Viral carcinogenesis_Homo sapiens_hsa052030.56658885
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56355381
66Peroxisome_Homo sapiens_hsa041460.56308722
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55866943
68Oxidative phosphorylation_Homo sapiens_hsa001900.55029700
69Metabolic pathways_Homo sapiens_hsa011000.53278609
70Fatty acid elongation_Homo sapiens_hsa000620.51090802
71Small cell lung cancer_Homo sapiens_hsa052220.51064737
72Tryptophan metabolism_Homo sapiens_hsa003800.50334136
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50056688
74Fatty acid metabolism_Homo sapiens_hsa012120.49617511
75Herpes simplex infection_Homo sapiens_hsa051680.47185640
76Adherens junction_Homo sapiens_hsa045200.45469682
77Caffeine metabolism_Homo sapiens_hsa002320.44829621
78Antigen processing and presentation_Homo sapiens_hsa046120.44707780
79Arginine and proline metabolism_Homo sapiens_hsa003300.44482588
80Arginine biosynthesis_Homo sapiens_hsa002200.39461494
81Pancreatic cancer_Homo sapiens_hsa052120.39058021
82Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36826263
83Alcoholism_Homo sapiens_hsa050340.36343231
84Prostate cancer_Homo sapiens_hsa052150.35983988
85Lysine degradation_Homo sapiens_hsa003100.34943200
86Non-small cell lung cancer_Homo sapiens_hsa052230.34519594
87TGF-beta signaling pathway_Homo sapiens_hsa043500.33467568
88Sulfur metabolism_Homo sapiens_hsa009200.33363712
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31977595
90Legionellosis_Homo sapiens_hsa051340.31464892
91Butanoate metabolism_Homo sapiens_hsa006500.30906765
92Hippo signaling pathway_Homo sapiens_hsa043900.30556257
93Galactose metabolism_Homo sapiens_hsa000520.29856132
94Protein export_Homo sapiens_hsa030600.29466095
95Colorectal cancer_Homo sapiens_hsa052100.28637847
96Thyroid cancer_Homo sapiens_hsa052160.26367275
97Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.24772393
98Nitrogen metabolism_Homo sapiens_hsa009100.24702318
99Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.23089976
100HTLV-I infection_Homo sapiens_hsa051660.22653050
101Tyrosine metabolism_Homo sapiens_hsa003500.22374662
102Vitamin digestion and absorption_Homo sapiens_hsa049770.21988052
103Retinol metabolism_Homo sapiens_hsa008300.21444375
104Chemical carcinogenesis_Homo sapiens_hsa052040.21439743
105Phenylalanine metabolism_Homo sapiens_hsa003600.20992302
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.20581621
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.19566699
108Glioma_Homo sapiens_hsa052140.18828366
109Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.16643734
110Endometrial cancer_Homo sapiens_hsa052130.16619305
111N-Glycan biosynthesis_Homo sapiens_hsa005100.16590033
112Apoptosis_Homo sapiens_hsa042100.16203387
113Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.15970193
114Melanoma_Homo sapiens_hsa052180.15688281
115AMPK signaling pathway_Homo sapiens_hsa041520.14945294
116Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.14933782
117Alzheimers disease_Homo sapiens_hsa050100.14013882
118HIF-1 signaling pathway_Homo sapiens_hsa040660.11382932
119Fatty acid biosynthesis_Homo sapiens_hsa000610.10757584
120Acute myeloid leukemia_Homo sapiens_hsa052210.10653237
121Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.10301302
122Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.09596418
123Fat digestion and absorption_Homo sapiens_hsa049750.09418197

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