DAW1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.09758865
2piRNA metabolic process (GO:0034587)9.02011934
3epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.96610695
4axoneme assembly (GO:0035082)8.56783854
5male meiosis (GO:0007140)7.78470240
6fusion of sperm to egg plasma membrane (GO:0007342)7.33052205
7multicellular organism reproduction (GO:0032504)7.00522022
8meiotic cell cycle (GO:0051321)6.53071068
9acrosome assembly (GO:0001675)6.38592571
10male meiosis I (GO:0007141)6.35666594
11sperm motility (GO:0030317)6.02995238
12sperm-egg recognition (GO:0035036)6.02246906
13ventricular system development (GO:0021591)5.99188797
14cell wall macromolecule catabolic process (GO:0016998)5.68519764
15cell wall macromolecule metabolic process (GO:0044036)5.68519764
16DNA methylation involved in gamete generation (GO:0043046)5.56045650
17binding of sperm to zona pellucida (GO:0007339)5.49422367
18plasma membrane fusion (GO:0045026)5.47976134
19meiosis I (GO:0007127)5.43936918
20reproduction (GO:0000003)5.42999820
21microtubule severing (GO:0051013)5.38119316
22regulation of meiosis I (GO:0060631)5.36110971
23intraciliary transport (GO:0042073)5.35190123
24synaptonemal complex organization (GO:0070193)5.34485172
25spermatid development (GO:0007286)5.29314369
26cell-cell recognition (GO:0009988)5.27241208
27single fertilization (GO:0007338)5.18611789
28cilium organization (GO:0044782)4.97572862
29nucleoside diphosphate phosphorylation (GO:0006165)4.94765347
30synaptonemal complex assembly (GO:0007130)4.93050676
31acrosome reaction (GO:0007340)4.88353027
32regulation of cilium movement (GO:0003352)4.82770597
33meiotic nuclear division (GO:0007126)4.82761264
34fertilization (GO:0009566)4.73753306
35cilium assembly (GO:0042384)4.69107010
36centriole replication (GO:0007099)4.55088043
37GTP biosynthetic process (GO:0006183)4.40678369
38left/right axis specification (GO:0070986)4.37633934
39cilium morphogenesis (GO:0060271)4.34671345
40spermatogenesis (GO:0007283)4.33738764
41male gamete generation (GO:0048232)4.32208353
42gamete generation (GO:0007276)4.27048875
43microtubule bundle formation (GO:0001578)4.20943391
44regulation of meiosis (GO:0040020)4.18512959
45behavioral response to nicotine (GO:0035095)4.16805187
46sulfation (GO:0051923)4.09003200
47cellular component assembly involved in morphogenesis (GO:0010927)4.07171108
48centriole assembly (GO:0098534)3.94619930
49microtubule-based movement (GO:0007018)3.92998723
50protein polyglutamylation (GO:0018095)3.88178521
51UTP biosynthetic process (GO:0006228)3.81630024
52microtubule depolymerization (GO:0007019)3.79812999
53cell proliferation in forebrain (GO:0021846)3.74763013
54retinal cone cell development (GO:0046549)3.66330522
55negative regulation of inclusion body assembly (GO:0090084)3.64573184
56regulation of meiotic cell cycle (GO:0051445)3.58576477
57negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.56550829
58negative regulation of meiosis (GO:0045835)3.53295313
59chromosome organization involved in meiosis (GO:0070192)3.52475670
60regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.52195526
61monoubiquitinated protein deubiquitination (GO:0035520)3.51723494
62meiotic cell cycle process (GO:1903046)3.48352721
63gene silencing by RNA (GO:0031047)3.47669678
64female gamete generation (GO:0007292)3.43771512
65UTP metabolic process (GO:0046051)3.43666880
66response to xenobiotic stimulus (GO:0009410)3.41959471
67multicellular organismal reproductive process (GO:0048609)3.31755187
68cellular process involved in reproduction in multicellular organism (GO:0022412)3.30029425
69regulation of inclusion body assembly (GO:0090083)3.29306443
70sperm capacitation (GO:0048240)3.24788355
71gamma-aminobutyric acid transport (GO:0015812)3.23913472
72cell projection assembly (GO:0030031)3.22073299
73left/right pattern formation (GO:0060972)3.20310070
74germ cell development (GO:0007281)3.19778761
75regulation of centriole replication (GO:0046599)3.15109367
76negative regulation of hormone biosynthetic process (GO:0032353)3.13664518
77negative regulation of hormone metabolic process (GO:0032351)3.13664518
78otic vesicle formation (GO:0030916)3.08391479
79regulation of germinal center formation (GO:0002634)3.05113599
80spermatid nucleus differentiation (GO:0007289)3.02205562
81negative regulation of meiotic cell cycle (GO:0051447)2.99204200
82protein K6-linked ubiquitination (GO:0085020)2.98429873
83protein localization to cilium (GO:0061512)2.95973765
84mitotic metaphase plate congression (GO:0007080)2.95953660
85smoothened signaling pathway (GO:0007224)2.95731852
86L-fucose catabolic process (GO:0042355)2.93091386
87fucose catabolic process (GO:0019317)2.93091386
88L-fucose metabolic process (GO:0042354)2.93091386
89histone exchange (GO:0043486)2.92624961
90attachment of spindle microtubules to kinetochore (GO:0008608)2.91526309
91determination of bilateral symmetry (GO:0009855)2.89069263
92regulation of female gonad development (GO:2000194)2.87485897
93regulation of exit from mitosis (GO:0007096)2.86785105
94negative regulation of T cell differentiation in thymus (GO:0033085)2.86255178
95negative regulation of transcription regulatory region DNA binding (GO:2000678)2.84920558
96mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.84703003
97mitochondrial respiratory chain complex I assembly (GO:0032981)2.84703003
98NADH dehydrogenase complex assembly (GO:0010257)2.84703003
99regulation of collateral sprouting (GO:0048670)2.84681263
100regulation of DNA endoreduplication (GO:0032875)2.84178237
101limb bud formation (GO:0060174)2.83129899
102determination of left/right symmetry (GO:0007368)2.82357678
103specification of symmetry (GO:0009799)2.81242787
104regulation of mononuclear cell migration (GO:0071675)2.80736395
105membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80371524
106DNA alkylation (GO:0006305)2.78870939
107DNA methylation (GO:0006306)2.78870939
108regulation of microtubule-based movement (GO:0060632)2.78591205
109spinal cord motor neuron differentiation (GO:0021522)2.78465232
110meiotic chromosome segregation (GO:0045132)2.78297516
111positive regulation of meiosis (GO:0045836)2.78230252
112deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.77582025
113histone H2A monoubiquitination (GO:0035518)2.77400660
114organelle assembly (GO:0070925)2.75384455
115neuron fate determination (GO:0048664)2.74252316
116oocyte maturation (GO:0001556)2.73870413
117regulation of retinoic acid receptor signaling pathway (GO:0048385)2.73854943
118female gonad development (GO:0008585)2.73799405
119regulation of spindle checkpoint (GO:0090231)2.71726412
120microtubule-based process (GO:0007017)2.70973160
121positive regulation of cAMP-mediated signaling (GO:0043950)2.69436812
122nonmotile primary cilium assembly (GO:0035058)2.68470093
123regulation of DNA methylation (GO:0044030)2.62308019
124water-soluble vitamin biosynthetic process (GO:0042364)2.61437942
125cellular response to ATP (GO:0071318)2.59136132
126detection of light stimulus involved in visual perception (GO:0050908)2.54493316
127detection of light stimulus involved in sensory perception (GO:0050962)2.54493316
128photoreceptor cell development (GO:0042461)2.53544393
129lateral sprouting from an epithelium (GO:0060601)2.53530434
130photoreceptor cell maintenance (GO:0045494)2.53487292
131intra-S DNA damage checkpoint (GO:0031573)2.52241424
132transmission of nerve impulse (GO:0019226)2.51495738
133DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.49909154
134pharyngeal system development (GO:0060037)2.48503628
135regulation of acrosome reaction (GO:0060046)2.46206503
136indole-containing compound catabolic process (GO:0042436)2.45975201
137indolalkylamine catabolic process (GO:0046218)2.45975201
138tryptophan catabolic process (GO:0006569)2.45975201
139diterpenoid biosynthetic process (GO:0016102)2.45476457
140primary alcohol catabolic process (GO:0034310)2.45439240
141pyrimidine-containing compound transmembrane transport (GO:0072531)2.43591455
142negative regulation of telomere maintenance (GO:0032205)2.43245170
143dentate gyrus development (GO:0021542)2.43117982
144magnesium ion transport (GO:0015693)2.41586277
145neural tube formation (GO:0001841)2.40437964
146exogenous drug catabolic process (GO:0042738)2.40401000
147one-carbon compound transport (GO:0019755)2.39811424
148somite development (GO:0061053)2.39711297
149regulation of secondary heart field cardioblast proliferation (GO:0003266)2.38658403
150regulation of cardioblast proliferation (GO:0003264)2.38658403
151regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.38543334
152protein K11-linked deubiquitination (GO:0035871)2.38495642
153synapsis (GO:0007129)2.38324073
154retinoic acid metabolic process (GO:0042573)2.37518545
155startle response (GO:0001964)2.36981939
156parental behavior (GO:0060746)2.36892788
157regulation of glomerulus development (GO:0090192)2.36672318
158forebrain morphogenesis (GO:0048853)2.36662247
159eye photoreceptor cell development (GO:0042462)2.35599260
160axonemal dynein complex assembly (GO:0070286)13.6649746
161cilium or flagellum-dependent cell motility (GO:0001539)12.4031734
162cilium movement (GO:0003341)11.8668279
163epithelial cilium movement (GO:0003351)10.1924551

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.07295100
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.04281207
3GBX2_23144817_ChIP-Seq_PC3_Human3.57773290
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.41565396
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.35157292
6KAP1_22055183_ChIP-Seq_ESCs_Mouse3.01777366
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.75883525
8GATA1_26923725_Chip-Seq_HPCs_Mouse2.61660374
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.41512515
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.38099296
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.21057474
12ZNF274_21170338_ChIP-Seq_K562_Hela2.18455796
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.14685582
14PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.11496858
15EZH2_22144423_ChIP-Seq_EOC_Human2.07935249
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.04556349
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.98132065
18RNF2_27304074_Chip-Seq_NSC_Mouse1.97516543
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.90401167
20NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.87456440
21EWS_26573619_Chip-Seq_HEK293_Human1.85844359
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83663972
23KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.80406905
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.79381775
25MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.78779080
26TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.77814626
27POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.77814626
28TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.74743151
29SUZ12_27294783_Chip-Seq_NPCs_Mouse1.74710675
30ELK4_26923725_Chip-Seq_MESODERM_Mouse1.71128896
31MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.69227942
32GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.68530005
33NANOG_18555785_Chip-Seq_ESCs_Mouse1.68139268
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.66791123
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.64358306
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.63867118
37EED_16625203_ChIP-ChIP_MESCs_Mouse1.61158407
38TAF15_26573619_Chip-Seq_HEK293_Human1.60151344
39ZFP57_27257070_Chip-Seq_ESCs_Mouse1.60042876
40NFE2_27457419_Chip-Seq_LIVER_Mouse1.59718587
41TAL1_26923725_Chip-Seq_HPCs_Mouse1.59514612
42FUS_26573619_Chip-Seq_HEK293_Human1.58791218
43TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.58022306
44IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.57107649
45CBP_20019798_ChIP-Seq_JUKART_Human1.57107649
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56853658
47DROSHA_22980978_ChIP-Seq_HELA_Human1.54541955
48EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.53274437
49SMAD4_21799915_ChIP-Seq_A2780_Human1.49054904
50STAT1_17558387_ChIP-Seq_HELA_Human1.48628495
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.48132892
52CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.47287688
53UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46403965
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.45576158
55LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43157351
56STAT6_21828071_ChIP-Seq_BEAS2B_Human1.42035047
57FOXM1_23109430_ChIP-Seq_U2OS_Human1.41997645
58CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.41694756
59ER_23166858_ChIP-Seq_MCF-7_Human1.41287245
60EZH2_27294783_Chip-Seq_NPCs_Mouse1.40097169
61RUNX1_26923725_Chip-Seq_HPCs_Mouse1.40065491
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.39982897
63PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39899985
64STAT3_23295773_ChIP-Seq_U87_Human1.36605961
65AR_25329375_ChIP-Seq_VCAP_Human1.34789935
66STAT3_18555785_Chip-Seq_ESCs_Mouse1.33588339
67KDM2B_26808549_Chip-Seq_REH_Human1.33178033
68VDR_22108803_ChIP-Seq_LS180_Human1.32968072
69FLI1_21867929_ChIP-Seq_TH2_Mouse1.32473520
70E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.30600891
71REST_21632747_ChIP-Seq_MESCs_Mouse1.30482300
72AR_21572438_ChIP-Seq_LNCaP_Human1.29849479
73AHR_22903824_ChIP-Seq_MCF-7_Human1.29242813
74SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28728246
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28485243
76OCT4_18555785_Chip-Seq_ESCs_Mouse1.28383626
77CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27764244
78P53_22387025_ChIP-Seq_ESCs_Mouse1.27047657
79PRDM14_20953172_ChIP-Seq_ESCs_Human1.26714630
80TCF4_22108803_ChIP-Seq_LS180_Human1.26133585
81ARNT_22903824_ChIP-Seq_MCF-7_Human1.25778554
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25527750
83WDR5_24793694_ChIP-Seq_LNCAP_Human1.25346979
84IGF1R_20145208_ChIP-Seq_DFB_Human1.24876235
85CRX_20693478_ChIP-Seq_RETINA_Mouse1.24614386
86SOX2_18555785_Chip-Seq_ESCs_Mouse1.24146898
87TBL1_22424771_ChIP-Seq_293T_Human1.24142716
88RUNX2_22187159_ChIP-Seq_PCA_Human1.24029410
89TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23846091
90EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.23759535
91SUZ12_18555785_Chip-Seq_ESCs_Mouse1.23433477
92KLF4_18555785_Chip-Seq_ESCs_Mouse1.23411214
93SALL1_21062744_ChIP-ChIP_HESCs_Human1.23295705
94TP53_16413492_ChIP-PET_HCT116_Human1.23075910
95ZFX_18555785_Chip-Seq_ESCs_Mouse1.22499249
96CMYC_18555785_Chip-Seq_ESCs_Mouse1.22002157
97EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.21622506
98LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20551484
99OCT4_21477851_ChIP-Seq_ESCs_Mouse1.19840526
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.19740207
101CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.19540484
102TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17998715
103GF1B_26923725_Chip-Seq_HPCs_Mouse1.16351635
104SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.16292009
105ESRRB_18555785_Chip-Seq_ESCs_Mouse1.16081395
106RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.15711639
107EZH2_27304074_Chip-Seq_ESCs_Mouse1.15367180
108P300_18555785_Chip-Seq_ESCs_Mouse1.14975373
109E2F1_18555785_Chip-Seq_ESCs_Mouse1.13915676
110IRF1_19129219_ChIP-ChIP_H3396_Human1.12658886
111SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.11851693
112EZH2_27294783_Chip-Seq_ESCs_Mouse1.11631677
113CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10678179
114CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10618393
115BMI1_23680149_ChIP-Seq_NPCS_Mouse1.10336242
116TP53_18474530_ChIP-ChIP_U2OS_Human1.10283326
117NANOG_19829295_ChIP-Seq_ESCs_Human1.09515865
118SOX2_19829295_ChIP-Seq_ESCs_Human1.09515865
119GATA3_21867929_ChIP-Seq_TH1_Mouse1.09397776
120SMAD4_21741376_ChIP-Seq_EPCs_Human1.09055036
121TCF4_23295773_ChIP-Seq_U87_Human1.08738681
122RUNX1_27457419_Chip-Seq_LIVER_Mouse1.08333496
123FOXA1_27270436_Chip-Seq_PROSTATE_Human1.08210963
124FOXA1_25329375_ChIP-Seq_VCAP_Human1.08210963
125P300_19829295_ChIP-Seq_ESCs_Human1.07590103
126TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.07383880
127CTCF_18555785_Chip-Seq_ESCs_Mouse1.07298864
128CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07137855
129OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07123341
130GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06292944
131RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05149009
132AUTS2_25519132_ChIP-Seq_293T-REX_Human1.04877955
133P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04724191
134ERG_20517297_ChIP-Seq_VCAP_Human1.04529634
135SOX2_21211035_ChIP-Seq_LN229_Gbm1.04233323
136SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.04220073
137BCAT_22108803_ChIP-Seq_LS180_Human1.04206001
138NMYC_18555785_Chip-Seq_ESCs_Mouse1.03836830
139GATA3_21867929_ChIP-Seq_CD8_Mouse1.03481149
140TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03256327
141FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02833564
142SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02520788
143JARID2_20075857_ChIP-Seq_MESCs_Mouse1.02465088
144AR_21909140_ChIP-Seq_LNCAP_Human1.02014588
145NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01868173
146JUN_21703547_ChIP-Seq_K562_Human1.01615892
147GF1_26923725_Chip-Seq_HPCs_Mouse1.01576449
148JARID2_20064375_ChIP-Seq_MESCs_Mouse1.01248834
149SMAD3_21741376_ChIP-Seq_ESCs_Human0.99057853
150CDX2_22108803_ChIP-Seq_LS180_Human0.98423004
151SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.97696502
152TP53_22573176_ChIP-Seq_HFKS_Human0.97529265
153POU5F1_16153702_ChIP-ChIP_HESCs_Human0.96273412
154KLF5_20875108_ChIP-Seq_MESCs_Mouse0.95540182
155RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95382108
156SMRT_27268052_Chip-Seq_Bcells_Human0.94498567

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology6.82864231
2MP0005410_abnormal_fertilization6.60159199
3MP0003136_yellow_coat_color5.58969714
4MP0001929_abnormal_gametogenesis4.11511677
5MP0008877_abnormal_DNA_methylation3.99850445
6MP0002102_abnormal_ear_morphology3.97879321
7MP0003646_muscle_fatigue3.67407952
8MP0003698_abnormal_male_reproductive3.63183117
9MP0002210_abnormal_sex_determination3.12779933
10MP0008875_abnormal_xenobiotic_pharmacok3.01740983
11MP0005451_abnormal_body_composition2.90920509
12MP0005623_abnormal_meninges_morphology2.81004945
13MP0003718_maternal_effect2.74018434
14MP0000653_abnormal_sex_gland2.65646032
15MP0006292_abnormal_olfactory_placode2.59330702
16MP0001145_abnormal_male_reproductive2.44053437
17MP0002161_abnormal_fertility/fecundity2.41576867
18MP0002138_abnormal_hepatobiliary_system2.32274225
19MP0001485_abnormal_pinna_reflex2.29903873
20MP0003937_abnormal_limbs/digits/tail_de2.06945809
21MP0003879_abnormal_hair_cell2.06582187
22MP0002249_abnormal_larynx_morphology1.99866480
23MP0000049_abnormal_middle_ear1.95042446
24MP0005646_abnormal_pituitary_gland1.94259307
25MP0004142_abnormal_muscle_tone1.94012977
26MP0002160_abnormal_reproductive_system1.93723004
27MP0008789_abnormal_olfactory_epithelium1.91453452
28MP0002272_abnormal_nervous_system1.87143288
29MP0002735_abnormal_chemical_nociception1.81319880
30MP0003880_abnormal_central_pattern1.80829263
31MP0002277_abnormal_respiratory_mucosa1.73604020
32MP0010094_abnormal_chromosome_stability1.73320201
33MP0004885_abnormal_endolymph1.71030561
34MP0002282_abnormal_trachea_morphology1.70641593
35MP0004043_abnormal_pH_regulation1.67512494
36MP0003950_abnormal_plasma_membrane1.67252092
37MP0001119_abnormal_female_reproductive1.65633004
38MP0003699_abnormal_female_reproductive1.61421230
39MP0009745_abnormal_behavioral_response1.59847074
40MP0009780_abnormal_chondrocyte_physiolo1.56126704
41MP0002876_abnormal_thyroid_physiology1.53758816
42MP0008057_abnormal_DNA_replication1.53404648
43MP0005395_other_phenotype1.53207254
44MP0000026_abnormal_inner_ear1.48611890
45MP0000569_abnormal_digit_pigmentation1.46692289
46MP0004381_abnormal_hair_follicle1.39160478
47MP0002234_abnormal_pharynx_morphology1.32044980
48MP0001486_abnormal_startle_reflex1.31782160
49MP0002638_abnormal_pupillary_reflex1.28371758
50MP0001963_abnormal_hearing_physiology1.28157371
51MP0003252_abnormal_bile_duct1.27742339
52MP0001851_eye_inflammation1.27595268
53MP0001293_anophthalmia1.27518221
54MP0008872_abnormal_physiological_respon1.25502325
55MP0003077_abnormal_cell_cycle1.24330373
56MP0005389_reproductive_system_phenotype1.24194874
57MP0003111_abnormal_nucleus_morphology1.23625983
58MP0005499_abnormal_olfactory_system1.23616842
59MP0005394_taste/olfaction_phenotype1.23616842
60MP0003195_calcinosis1.23578463
61MP0006276_abnormal_autonomic_nervous1.23547250
62MP0005084_abnormal_gallbladder_morpholo1.22371349
63MP0005253_abnormal_eye_physiology1.20547437
64MP0005423_abnormal_somatic_nervous1.19273769
65MP0001970_abnormal_pain_threshold1.18026258
66MP0005647_abnormal_sex_gland1.16847606
67MP0004742_abnormal_vestibular_system1.16543077
68MP0001984_abnormal_olfaction1.13573126
69MP0009046_muscle_twitch1.10935520
70MP0009250_abnormal_appendicular_skeleto1.10735005
71MP0001440_abnormal_grooming_behavior1.10410830
72MP0002064_seizures1.08224495
73MP0002572_abnormal_emotion/affect_behav1.06213228
74MP0005195_abnormal_posterior_eye1.05572625
75MP0004145_abnormal_muscle_electrophysio1.05087995
76MP0001968_abnormal_touch/_nociception1.05063445
77MP0003693_abnormal_embryo_hatching1.03952005
78MP0008932_abnormal_embryonic_tissue1.02557881
79MP0004019_abnormal_vitamin_homeostasis0.98796840
80MP0003635_abnormal_synaptic_transmissio0.97800897
81MP0002928_abnormal_bile_duct0.97127647
82MP0004134_abnormal_chest_morphology0.95247628
83MP0003890_abnormal_embryonic-extraembry0.94871336
84MP0005174_abnormal_tail_pigmentation0.94158144
85MP0002557_abnormal_social/conspecific_i0.92767604
86MP0002733_abnormal_thermal_nociception0.92615563
87MP0008058_abnormal_DNA_repair0.91640654
88MP0002139_abnormal_hepatobiliary_system0.91517072
89MP0008007_abnormal_cellular_replicative0.91464874
90MP0000579_abnormal_nail_morphology0.90974274
91MP0002163_abnormal_gland_morphology0.90646227
92MP0000678_abnormal_parathyroid_gland0.90564219
93MP0005377_hearing/vestibular/ear_phenot0.89353886
94MP0003878_abnormal_ear_physiology0.89353886
95MP0005083_abnormal_biliary_tract0.87228458
96MP0002067_abnormal_sensory_capabilities0.86971214
97MP0003861_abnormal_nervous_system0.85703778
98MP0002938_white_spotting0.85383227
99MP0003315_abnormal_perineum_morphology0.85290699
100MP0002063_abnormal_learning/memory/cond0.84864047
101MP0002116_abnormal_craniofacial_bone0.82289490
102MP0002084_abnormal_developmental_patter0.82222751
103MP0002085_abnormal_embryonic_tissue0.81960274
104MP0009379_abnormal_foot_pigmentation0.81123957
105MP0004133_heterotaxia0.80694138
106MP0003119_abnormal_digestive_system0.79501484
107MP0003755_abnormal_palate_morphology0.78755332
108MP0000462_abnormal_digestive_system0.78459217
109MP0001986_abnormal_taste_sensitivity0.77558620
110MP0001529_abnormal_vocalization0.76973620
111MP0000566_synostosis0.76921092
112MP0000427_abnormal_hair_cycle0.76051431
113MP0003123_paternal_imprinting0.75867051
114MP0000631_abnormal_neuroendocrine_gland0.74863408
115MP0001324_abnormal_eye_pigmentation0.74789298
116MP0002233_abnormal_nose_morphology0.74278419
117MP0001502_abnormal_circadian_rhythm0.74221112
118MP0008004_abnormal_stomach_pH0.73607117
119MP0003787_abnormal_imprinting0.73364754
120MP0002168_other_aberrant_phenotype0.73120794
121MP0005397_hematopoietic_system_phenotyp0.72348044
122MP0001545_abnormal_hematopoietic_system0.72348044
123MP0000778_abnormal_nervous_system0.71268704
124MP0000432_abnormal_head_morphology0.69589490
125MP0004233_abnormal_muscle_weight0.69323893
126MP0002109_abnormal_limb_morphology0.67170046
127MP0006072_abnormal_retinal_apoptosis0.64683477
128MP0008995_early_reproductive_senescence0.63684396
129MP0005408_hypopigmentation0.63321302
130MP0003329_amyloid_beta_deposits0.61838860
131MP0003121_genomic_imprinting0.61552394
132MP0000383_abnormal_hair_follicle0.60520967
133MP0001905_abnormal_dopamine_level0.60379403
134MP0001765_abnormal_ion_homeostasis0.59625217
135MP0000613_abnormal_salivary_gland0.59405900
136MP0004270_analgesia0.58877560
137MP0003938_abnormal_ear_development0.57566952
138MP0002734_abnormal_mechanical_nocicepti0.56313549
139MP0002152_abnormal_brain_morphology0.53715869
140MP0005551_abnormal_eye_electrophysiolog0.53564661
141MP0005187_abnormal_penis_morphology0.52634837
142MP0010030_abnormal_orbit_morphology0.52463738
143MP0002752_abnormal_somatic_nervous0.50871249
144MP0005670_abnormal_white_adipose0.50505519
145MP0000428_abnormal_craniofacial_morphol0.50150208
146MP0003011_delayed_dark_adaptation0.49990455
147MP0000639_abnormal_adrenal_gland0.49716696
148MP0001340_abnormal_eyelid_morphology0.49667835
149MP0001919_abnormal_reproductive_system0.49343070
150MP0000538_abnormal_urinary_bladder0.48136534
151MP0010678_abnormal_skin_adnexa0.47380857
152MP0002971_abnormal_brown_adipose0.44785967
153MP0000350_abnormal_cell_proliferation0.44011506
154MP0001915_intracranial_hemorrhage0.43869971
155MP0001270_distended_abdomen0.43327297
156MP0003935_abnormal_craniofacial_develop0.42385220

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.38055935
2Absent/shortened dynein arms (HP:0200106)8.61657234
3Dynein arm defect of respiratory motile cilia (HP:0012255)8.61657234
4Abnormal respiratory motile cilium morphology (HP:0005938)8.43739081
5Abnormal respiratory epithelium morphology (HP:0012253)8.43739081
6Chronic bronchitis (HP:0004469)6.90170886
7Bronchiectasis (HP:0002110)5.74806665
8Nasal polyposis (HP:0100582)5.44225516
9Infertility (HP:0000789)5.05584566
10Male infertility (HP:0003251)4.84241328
11Abnormality of the nasal mucosa (HP:0000433)4.37456060
12Pancreatic fibrosis (HP:0100732)3.82469563
13Nephronophthisis (HP:0000090)3.77307806
14True hermaphroditism (HP:0010459)3.66414682
15Bronchitis (HP:0012387)3.58686649
16Recurrent sinusitis (HP:0011108)3.12994392
17Medial flaring of the eyebrow (HP:0010747)3.05657341
18Occipital encephalocele (HP:0002085)3.01923533
19Chronic sinusitis (HP:0011109)3.01354688
20Abnormality of midbrain morphology (HP:0002418)2.97624811
21Molar tooth sign on MRI (HP:0002419)2.97624811
22Pancreatic cysts (HP:0001737)2.95449798
23Abnormality of the renal medulla (HP:0100957)2.93408145
24Supernumerary spleens (HP:0009799)2.91390944
25Recurrent otitis media (HP:0000403)2.79536710
26Aplasia/Hypoplasia of the tongue (HP:0010295)2.78790430
27Absent rod-and cone-mediated responses on ERG (HP:0007688)2.77107643
28Gait imbalance (HP:0002141)2.72804261
29Congenital primary aphakia (HP:0007707)2.70848790
30Cystic liver disease (HP:0006706)2.57540815
31Postaxial foot polydactyly (HP:0001830)2.49480576
32Abnormal rod and cone electroretinograms (HP:0008323)2.44258621
33Congenital hepatic fibrosis (HP:0002612)2.38987351
34Abnormality of dentin (HP:0010299)2.35877151
35Nephrogenic diabetes insipidus (HP:0009806)2.32467829
36Poor coordination (HP:0002370)2.29147125
37Abolished electroretinogram (ERG) (HP:0000550)2.23566464
38Decreased central vision (HP:0007663)2.19494747
39Median cleft lip (HP:0000161)2.17062500
40Chromosomal breakage induced by crosslinking agents (HP:0003221)2.15404371
41Chromsome breakage (HP:0040012)2.13578495
42Decreased circulating renin level (HP:0003351)2.12206774
43Aplasia/Hypoplasia of the spleen (HP:0010451)2.12188715
44Pendular nystagmus (HP:0012043)2.10023819
45Genital tract atresia (HP:0001827)2.09626252
46Asplenia (HP:0001746)2.08827770
47Progressive cerebellar ataxia (HP:0002073)2.06377545
48Genetic anticipation (HP:0003743)2.06072658
49Papillary thyroid carcinoma (HP:0002895)2.04008703
50Type II lissencephaly (HP:0007260)2.03813491
51Bile duct proliferation (HP:0001408)2.00923427
52Abnormal biliary tract physiology (HP:0012439)2.00923427
53Male pseudohermaphroditism (HP:0000037)2.00414932
54Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.1565899
55Abnormal respiratory motile cilium physiology (HP:0012261)11.8899250
56Abnormal ciliary motility (HP:0012262)11.3171962
57Fibular hypoplasia (HP:0003038)1.96392468
58Tubulointerstitial nephritis (HP:0001970)1.95895739
59Vaginal atresia (HP:0000148)1.94968310
60Microglossia (HP:0000171)1.92568158
61Keratoconus (HP:0000563)1.89318097
62Increased corneal curvature (HP:0100692)1.89318097
63Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.88449918
64Tubular atrophy (HP:0000092)1.86312651
65Septo-optic dysplasia (HP:0100842)1.81864065
66Aplasia/Hypoplasia of the lens (HP:0008063)1.81288987
67Congenital stationary night blindness (HP:0007642)1.79503990
68Postaxial hand polydactyly (HP:0001162)1.79439198
69Aplasia/hypoplasia of the uterus (HP:0008684)1.76413901
70Aplasia/Hypoplasia of the tibia (HP:0005772)1.76261085
71Adrenal hypoplasia (HP:0000835)1.75278594
72Abnormality of the dental pulp (HP:0006479)1.74361816
73Short tibia (HP:0005736)1.72615513
74Short nail (HP:0001799)1.72160537
75Severe visual impairment (HP:0001141)1.71744834
76Bony spicule pigmentary retinopathy (HP:0007737)1.71464585
77Preaxial hand polydactyly (HP:0001177)1.71399648
78Anencephaly (HP:0002323)1.71124110
79Hyperactive renin-angiotensin system (HP:0000841)1.68328612
80Hypoplasia of the uterus (HP:0000013)1.68087078
81Oligodactyly (hands) (HP:0001180)1.67885119
82Stage 5 chronic kidney disease (HP:0003774)1.66898176
83Conjunctival hamartoma (HP:0100780)1.66599800
84Abnormality of the middle phalanges of the toes (HP:0010183)1.65674558
85Methylmalonic acidemia (HP:0002912)1.64708829
86Oculomotor apraxia (HP:0000657)1.64036918
87Hypoplastic pelvis (HP:0008839)1.62932866
88Sclerocornea (HP:0000647)1.62605280
89Abnormal spermatogenesis (HP:0008669)1.61380345
90Abnormality of the dental root (HP:0006486)1.61256494
91Taurodontia (HP:0000679)1.61256494
92Abnormality of permanent molar morphology (HP:0011071)1.61256494
93Short femoral neck (HP:0100864)1.58632093
94Abdominal situs inversus (HP:0003363)1.58166045
95Abnormality of abdominal situs (HP:0011620)1.58166045
96Tubulointerstitial abnormality (HP:0001969)1.54972570
97Symphalangism affecting the phalanges of the hand (HP:0009773)1.53641586
98Azoospermia (HP:0000027)1.53559690
99Atelectasis (HP:0100750)1.51890214
100Polyuria (HP:0000103)1.51156373
101Broad foot (HP:0001769)1.50216284
102Anophthalmia (HP:0000528)1.50141363
103Abnormality of molar morphology (HP:0011070)1.50104612
104Abnormality of molar (HP:0011077)1.50104612
105Aplasia/Hypoplasia of the fibula (HP:0006492)1.49292147
106Intellectual disability, moderate (HP:0002342)1.49116104
107Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.48353987
108Gaze-evoked nystagmus (HP:0000640)1.48326691
109Renal dysplasia (HP:0000110)1.47857333
110Optic nerve hypoplasia (HP:0000609)1.46762410
111Chronic hepatic failure (HP:0100626)1.45065563
112Retinitis pigmentosa (HP:0000510)1.44428680
113Highly arched eyebrow (HP:0002553)1.43109407
114Attenuation of retinal blood vessels (HP:0007843)1.42277644
115Aganglionic megacolon (HP:0002251)1.40795547
116Congenital sensorineural hearing impairment (HP:0008527)1.40569040
117Osteomalacia (HP:0002749)1.40198419
118Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.39308782
119Recurrent bronchitis (HP:0002837)1.37697157
120Bifid tongue (HP:0010297)1.36863894
12111 pairs of ribs (HP:0000878)1.34834913
122Facial hemangioma (HP:0000329)1.34437756
123Abnormality of the renal cortex (HP:0011035)1.33597491
124Facial cleft (HP:0002006)1.28702114
125Abnormality of the fovea (HP:0000493)1.27066443
126Furrowed tongue (HP:0000221)1.26549334
127Sloping forehead (HP:0000340)1.26409733
128Abnormality of macular pigmentation (HP:0008002)1.24414328
129Polycystic ovaries (HP:0000147)1.21882596
130Sex reversal (HP:0012245)1.21010318
131Abnormal sex determination (HP:0012244)1.21010318
132Abnormality of lateral ventricle (HP:0030047)1.20868489
133Hypodontia (HP:0000668)1.20866061
134Narrow forehead (HP:0000341)1.20174423
135Polydipsia (HP:0001959)1.19979061
136Abnormal drinking behavior (HP:0030082)1.19979061
137Ectopic kidney (HP:0000086)1.19786835
138Aplasia/Hypoplasia of the uvula (HP:0010293)1.18928191
139Astigmatism (HP:0000483)1.16253231
140Polycystic kidney dysplasia (HP:0000113)1.15850997
141Tubulointerstitial fibrosis (HP:0005576)1.15392305
142Multicystic kidney dysplasia (HP:0000003)1.13382350

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.06848602
2PDK43.99064433
3PDK33.99064433
4FRK3.59055463
5MAPK153.40637182
6PNCK3.15348014
7MUSK3.13154531
8LATS23.10634230
9MAP3K63.01645105
10STK38L2.87973634
11ADRBK22.71186780
12MST42.65670071
13PLK42.53074420
14PRKD32.44174547
15ERBB42.44056297
16PDK22.33587190
17WNK32.28361832
18TTK2.20458983
19TLK12.18150337
20EEF2K2.12389367
21MAP3K92.08267786
22CDC71.96899319
23MOS1.91582132
24NTRK21.89372345
25STK31.88519080
26KSR21.82430361
27CASK1.74061979
28INSRR1.73587954
29MAP4K21.71431442
30ZAK1.68790452
31BRAF1.61514880
32NEK21.60258841
33DYRK21.48599979
34TAOK31.48574059
35STK241.42882248
36CHEK21.39734111
37MAPKAPK31.33357367
38STK161.33047487
39STK381.30779109
40ARAF1.28338980
41RAF11.28138595
42DMPK1.24563193
43TIE11.13934022
44MAP3K41.11314365
45ICK1.06490492
46WEE11.06107374
47TYRO31.02042524
48BMPR21.01678310
49MAPKAPK51.01617603
50FGR1.01574999
51MELK1.01457022
52MAP3K131.01302191
53MAP2K71.00163902
54CDK90.98412100
55BRSK20.98315173
56OXSR10.97871912
57PAK60.97848983
58PLK10.97422233
59TAF10.95334407
60BCKDK0.94680641
61STK390.91179715
62PTK2B0.91178871
63AURKA0.90542749
64MET0.89736190
65MAPK130.88668320
66KSR10.86208268
67NME10.85063046
68IRAK10.83072270
69PRKCI0.81345617
70VRK10.81081502
71CAMK1G0.79170524
72TAOK10.76458183
73CSNK1G20.76427439
74EIF2AK30.76331285
75BMPR1B0.76145315
76DYRK30.76108378
77CDK30.73743739
78NTRK30.72580218
79TESK10.72522691
80ADRBK10.72109772
81WNK40.71100849
82EPHA40.70981186
83STK100.70006145
84ACVR1B0.68692870
85NEK60.67460931
86PRKCE0.67030662
87ABL20.66957976
88PINK10.63109067
89NUAK10.60876027
90CAMK1D0.60811778
91TXK0.60338069
92EPHA20.59027846
93PLK30.58793770
94CSNK1G30.55258516
95PRKACA0.53844806
96BRSK10.53792517
97PRKAA20.53582540
98PKN10.52185261
99ERBB20.52158044
100VRK20.52142944
101TGFBR10.52138855
102CDK80.51295159
103GRK10.51153252
104NLK0.50554955
105TSSK60.50549654
106CHEK10.50087550
107MARK20.49955800
108CSNK1A1L0.49330089
109ATM0.48179415
110MAP2K40.46973925
111MAP3K120.45802085
112PLK20.44578485
113TRPM70.44441185
114SGK20.44259729
115PRKD20.43564187
116PRKAA10.43146536
117MARK10.41719589
118PRKG10.41509036
119PHKG10.41425880
120PHKG20.41425880
121GRK50.41355681
122LMTK20.41095426
123AURKB0.40724139
124CAMK2A0.39012819
125PRKCZ0.38566435
126WNK10.38408335
127SGK10.38279178
128CSNK1G10.36642356
129CSNK1A10.35749539
130CDK190.35635393
131MKNK20.35145067
132CAMKK20.34299745
133PRKCA0.34263924
134GRK70.33816815
135MAP2K60.33531141
136PRKCQ0.32717654
137CAMK10.32389612
138MAPK100.30489076
139PDK10.30174748
140ABL10.24789908
141DYRK1A0.24163061
142RPS6KA40.23762021
143TNIK0.23122523
144HIPK20.21430190
145MAP3K50.21118186
146ATR0.20456325
147CDK150.20139519
148NEK90.19742814
149PRKCG0.18180712
150SGK4940.18018972
151SGK2230.18018972
152CDK10.17644392
153SRPK10.17521942
154CDK180.17333789

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.92859425
2Basal transcription factors_Homo sapiens_hsa030223.60241489
3Cell cycle_Homo sapiens_hsa041103.27363692
4Fanconi anemia pathway_Homo sapiens_hsa034603.10358256
5Dorso-ventral axis formation_Homo sapiens_hsa043202.96892372
6Circadian rhythm_Homo sapiens_hsa047102.87530050
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.84200886
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.82229700
9Linoleic acid metabolism_Homo sapiens_hsa005912.78871993
10Ether lipid metabolism_Homo sapiens_hsa005652.77692935
11Caffeine metabolism_Homo sapiens_hsa002322.75855141
12Ovarian steroidogenesis_Homo sapiens_hsa049132.71163716
13Chemical carcinogenesis_Homo sapiens_hsa052042.49451599
14Oocyte meiosis_Homo sapiens_hsa041142.46542249
15Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.41122458
16RNA degradation_Homo sapiens_hsa030182.29531686
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.22271353
18Phototransduction_Homo sapiens_hsa047442.22202750
19Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.02626854
20Homologous recombination_Homo sapiens_hsa034402.01896347
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.96743927
22Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.75950596
23Pyruvate metabolism_Homo sapiens_hsa006201.73477977
24TGF-beta signaling pathway_Homo sapiens_hsa043501.68313497
25Nitrogen metabolism_Homo sapiens_hsa009101.67475173
26Oxidative phosphorylation_Homo sapiens_hsa001901.64524963
27Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.58857185
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.56839915
29Glycerophospholipid metabolism_Homo sapiens_hsa005641.50893477
30Taste transduction_Homo sapiens_hsa047421.38166678
31Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.37195664
32Huntingtons disease_Homo sapiens_hsa050161.37006420
33Selenocompound metabolism_Homo sapiens_hsa004501.36060274
34Morphine addiction_Homo sapiens_hsa050321.32341915
35beta-Alanine metabolism_Homo sapiens_hsa004101.32254883
36Cardiac muscle contraction_Homo sapiens_hsa042601.26695958
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.25395566
38Parkinsons disease_Homo sapiens_hsa050121.23412171
39Tryptophan metabolism_Homo sapiens_hsa003801.22686797
40Nucleotide excision repair_Homo sapiens_hsa034201.19475767
41Glucagon signaling pathway_Homo sapiens_hsa049221.17794257
42ABC transporters_Homo sapiens_hsa020101.16469913
43Pentose phosphate pathway_Homo sapiens_hsa000301.15166034
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.12448007
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.11811167
46Amphetamine addiction_Homo sapiens_hsa050311.10276562
47Vitamin digestion and absorption_Homo sapiens_hsa049771.09204702
48Hedgehog signaling pathway_Homo sapiens_hsa043401.08568703
49Purine metabolism_Homo sapiens_hsa002301.04838534
50Cocaine addiction_Homo sapiens_hsa050301.03763185
51GnRH signaling pathway_Homo sapiens_hsa049121.02736340
52Primary bile acid biosynthesis_Homo sapiens_hsa001201.02692297
53Peroxisome_Homo sapiens_hsa041461.01983235
54Arachidonic acid metabolism_Homo sapiens_hsa005901.00810714
55Tyrosine metabolism_Homo sapiens_hsa003500.99690118
56Protein export_Homo sapiens_hsa030600.99560138
57Salivary secretion_Homo sapiens_hsa049700.94635565
58Pancreatic cancer_Homo sapiens_hsa052120.94501131
59Systemic lupus erythematosus_Homo sapiens_hsa053220.92996130
60Choline metabolism in cancer_Homo sapiens_hsa052310.92750660
61GABAergic synapse_Homo sapiens_hsa047270.92257000
62Alzheimers disease_Homo sapiens_hsa050100.91830927
63p53 signaling pathway_Homo sapiens_hsa041150.90239674
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.89585547
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.86142150
66Propanoate metabolism_Homo sapiens_hsa006400.85909557
67Hippo signaling pathway_Homo sapiens_hsa043900.84678583
68Estrogen signaling pathway_Homo sapiens_hsa049150.84375641
69Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.83083045
70RNA transport_Homo sapiens_hsa030130.82465532
71Fatty acid biosynthesis_Homo sapiens_hsa000610.82259250
72Wnt signaling pathway_Homo sapiens_hsa043100.80963847
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.80840206
74Sphingolipid metabolism_Homo sapiens_hsa006000.80363935
75Intestinal immune network for IgA production_Homo sapiens_hsa046720.78319302
76RNA polymerase_Homo sapiens_hsa030200.77773192
77Glutamatergic synapse_Homo sapiens_hsa047240.77682739
78Renal cell carcinoma_Homo sapiens_hsa052110.75681414
79Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75316925
80cAMP signaling pathway_Homo sapiens_hsa040240.74866951
81Prolactin signaling pathway_Homo sapiens_hsa049170.73787289
82Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.73651881
83Nicotine addiction_Homo sapiens_hsa050330.72663033
84One carbon pool by folate_Homo sapiens_hsa006700.71982157
85Pyrimidine metabolism_Homo sapiens_hsa002400.71473995
86mRNA surveillance pathway_Homo sapiens_hsa030150.71100733
87Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.70020009
88Inositol phosphate metabolism_Homo sapiens_hsa005620.69527344
89Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69408111
90Glycerolipid metabolism_Homo sapiens_hsa005610.69034025
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.67006564
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64882523
93Circadian entrainment_Homo sapiens_hsa047130.64187032
94Regulation of autophagy_Homo sapiens_hsa041400.63316007
95Phenylalanine metabolism_Homo sapiens_hsa003600.61052376
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56385084
97Ras signaling pathway_Homo sapiens_hsa040140.55031194
98Alcoholism_Homo sapiens_hsa050340.54304233
99Colorectal cancer_Homo sapiens_hsa052100.53777968
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.53213525
101Basal cell carcinoma_Homo sapiens_hsa052170.53062761
102Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51960698
103Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.51710556
104Long-term depression_Homo sapiens_hsa047300.51698046
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51334412
106Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50249342
107Oxytocin signaling pathway_Homo sapiens_hsa049210.49804726
108Axon guidance_Homo sapiens_hsa043600.49671477
109Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.49534417
110MAPK signaling pathway_Homo sapiens_hsa040100.48809078
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48587174
112Melanoma_Homo sapiens_hsa052180.47705278
113Metabolic pathways_Homo sapiens_hsa011000.47607226
114Asthma_Homo sapiens_hsa053100.47599378
115Insulin secretion_Homo sapiens_hsa049110.46927017
116Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46842527
117MicroRNAs in cancer_Homo sapiens_hsa052060.45918491
118Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45900037
119Adherens junction_Homo sapiens_hsa045200.42671481
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.41577329
121Serotonergic synapse_Homo sapiens_hsa047260.41479266
122AMPK signaling pathway_Homo sapiens_hsa041520.41436791
123Fatty acid degradation_Homo sapiens_hsa000710.40234608
124Olfactory transduction_Homo sapiens_hsa047400.37921097
125cGMP-PKG signaling pathway_Homo sapiens_hsa040220.37670028
126Notch signaling pathway_Homo sapiens_hsa043300.36504778
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36276796
128HTLV-I infection_Homo sapiens_hsa051660.35718913
129Base excision repair_Homo sapiens_hsa034100.35714457
130Sulfur metabolism_Homo sapiens_hsa009200.35226928
131Histidine metabolism_Homo sapiens_hsa003400.34772232
132Calcium signaling pathway_Homo sapiens_hsa040200.33891260
133Retinol metabolism_Homo sapiens_hsa008300.33454858
134VEGF signaling pathway_Homo sapiens_hsa043700.33415112
135Thyroid hormone synthesis_Homo sapiens_hsa049180.32966830
136Other glycan degradation_Homo sapiens_hsa005110.32481127
137Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32244992
138Glutathione metabolism_Homo sapiens_hsa004800.31151470
139Mineral absorption_Homo sapiens_hsa049780.30865627
140Long-term potentiation_Homo sapiens_hsa047200.30461888
141Aldosterone synthesis and secretion_Homo sapiens_hsa049250.30134899
142Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.30088609
143Phospholipase D signaling pathway_Homo sapiens_hsa040720.29412311
144Gastric acid secretion_Homo sapiens_hsa049710.28985052
145Hepatitis B_Homo sapiens_hsa051610.28085686
146Longevity regulating pathway - mammal_Homo sapiens_hsa042110.26992952
147Dopaminergic synapse_Homo sapiens_hsa047280.26965863
148Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26392848
149Renin secretion_Homo sapiens_hsa049240.24185431
150Butanoate metabolism_Homo sapiens_hsa006500.23699967
151PPAR signaling pathway_Homo sapiens_hsa033200.22692247
152Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.22046158
153Melanogenesis_Homo sapiens_hsa049160.20748277
154Rheumatoid arthritis_Homo sapiens_hsa053230.19999208

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