DBNDD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)6.07533020
2response to pheromone (GO:0019236)5.44531330
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.10211605
4cell migration in hindbrain (GO:0021535)4.95786980
5vocalization behavior (GO:0071625)4.81218550
6neuron recognition (GO:0008038)4.81077742
7layer formation in cerebral cortex (GO:0021819)4.79919949
8synaptic vesicle exocytosis (GO:0016079)4.68640411
9pyrimidine nucleobase catabolic process (GO:0006208)4.60770954
10axonal fasciculation (GO:0007413)4.57934131
11regulation of synapse structural plasticity (GO:0051823)4.50836470
12regulation of short-term neuronal synaptic plasticity (GO:0048172)4.48466690
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.40553262
14negative regulation of microtubule polymerization (GO:0031115)4.26217896
15regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.24850104
16positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.08791334
17synaptic vesicle maturation (GO:0016188)3.97991186
18protein localization to synapse (GO:0035418)3.94311545
19regulation of synaptic vesicle exocytosis (GO:2000300)3.93157409
20glutamate secretion (GO:0014047)3.88639525
21positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.82038266
22synaptic vesicle endocytosis (GO:0048488)3.81710555
23regulation of glutamate receptor signaling pathway (GO:1900449)3.75285109
24neurotransmitter secretion (GO:0007269)3.64996977
25nucleobase catabolic process (GO:0046113)3.62441681
26positive regulation of synapse maturation (GO:0090129)3.60208873
27cerebellar Purkinje cell differentiation (GO:0021702)3.55255110
28dendritic spine morphogenesis (GO:0060997)3.54363827
29regulation of synaptic vesicle transport (GO:1902803)3.54109351
30establishment of mitochondrion localization (GO:0051654)3.50454866
31central nervous system projection neuron axonogenesis (GO:0021952)3.41976925
32behavioral response to ethanol (GO:0048149)3.40666489
33cerebellar granule cell differentiation (GO:0021707)3.38720599
34postsynaptic membrane organization (GO:0001941)3.34387412
35hippocampus development (GO:0021766)3.33732352
36peptidyl-arginine omega-N-methylation (GO:0035247)3.33557056
37establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.33034818
38mitochondrion transport along microtubule (GO:0047497)3.33034818
39ionotropic glutamate receptor signaling pathway (GO:0035235)3.32390453
40positive regulation of synapse assembly (GO:0051965)3.30632255
41positive regulation of dendritic spine morphogenesis (GO:0061003)3.28557677
42glutamate receptor signaling pathway (GO:0007215)3.24177894
43presynaptic membrane organization (GO:0097090)3.23372787
44synaptic transmission, glutamatergic (GO:0035249)3.22686618
45neuron-neuron synaptic transmission (GO:0007270)3.22332763
46behavioral response to cocaine (GO:0048148)3.19746829
47sodium ion export (GO:0071436)3.19530092
48regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.16004348
49protein polyglutamylation (GO:0018095)3.15510186
50mating behavior (GO:0007617)3.15483512
51dendrite morphogenesis (GO:0048813)3.13785935
52proline transport (GO:0015824)3.12858911
53histone arginine methylation (GO:0034969)3.12282096
54synapse assembly (GO:0007416)3.11750514
55regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.10393773
56regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.10393773
57regulation of neuronal synaptic plasticity (GO:0048168)3.09870932
58exploration behavior (GO:0035640)3.09037567
59neuronal action potential propagation (GO:0019227)3.07297621
60neurotransmitter transport (GO:0006836)3.06199097
61locomotory exploration behavior (GO:0035641)3.05951240
62innervation (GO:0060384)3.05224612
63negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.02628688
64membrane hyperpolarization (GO:0060081)3.02613490
65adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.01465385
66regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.00606959
67dopamine receptor signaling pathway (GO:0007212)2.98781431
68behavioral fear response (GO:0001662)2.97340460
69behavioral defense response (GO:0002209)2.97340460
70regulation of synapse maturation (GO:0090128)2.96113027
71G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.94994812
72cerebellar Purkinje cell layer development (GO:0021680)2.94618492
73chaperone-mediated protein transport (GO:0072321)2.94578174
74intraspecies interaction between organisms (GO:0051703)2.92451095
75social behavior (GO:0035176)2.92451095
76prepulse inhibition (GO:0060134)2.91109224
77cellular potassium ion homeostasis (GO:0030007)2.90680870
78peptidyl-arginine N-methylation (GO:0035246)2.89988661
79peptidyl-arginine methylation (GO:0018216)2.89988661
80presynaptic membrane assembly (GO:0097105)2.89900433
81regulation of long-term neuronal synaptic plasticity (GO:0048169)2.89711272
82establishment of synaptic vesicle localization (GO:0097480)2.89655434
83synaptic vesicle transport (GO:0048489)2.89655434
84response to auditory stimulus (GO:0010996)2.89356576
85regulation of neurotransmitter levels (GO:0001505)2.87186653
86sensory perception of smell (GO:0007608)2.86520358
87epithelial cilium movement (GO:0003351)2.85537350
88proline biosynthetic process (GO:0006561)2.85273555
89positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.84392670
90cerebellum development (GO:0021549)2.83694223
91regulation of synaptic transmission, dopaminergic (GO:0032225)2.83465690
92piRNA metabolic process (GO:0034587)2.83427501
93positive regulation of membrane potential (GO:0045838)2.82661829
94dendrite development (GO:0016358)2.82508677
95neurotransmitter-gated ion channel clustering (GO:0072578)2.81584988
96fear response (GO:0042596)2.80323643
97auditory behavior (GO:0031223)2.79674086
98cilium movement (GO:0003341)2.79452702
99cerebral cortex neuron differentiation (GO:0021895)2.78977297
100regulation of synaptic transmission, glutamatergic (GO:0051966)2.78292555
101regulation of mammary gland epithelial cell proliferation (GO:0033599)2.77173593
102synaptic vesicle docking involved in exocytosis (GO:0016081)2.77004279
103membrane depolarization during action potential (GO:0086010)2.76769139
104gamma-aminobutyric acid transport (GO:0015812)2.76757447
105response to histamine (GO:0034776)2.76414963
106gamma-aminobutyric acid signaling pathway (GO:0007214)2.76377896
107L-serine metabolic process (GO:0006563)2.76242878
108axon extension (GO:0048675)2.75948438
109regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.75423461
110regulation of neurotransmitter secretion (GO:0046928)2.75401758
111cell-cell junction maintenance (GO:0045217)2.75270194
112regulation of excitatory postsynaptic membrane potential (GO:0060079)2.73759577
113establishment of vesicle localization (GO:0051650)2.73554026
114regulation of postsynaptic membrane potential (GO:0060078)2.73151888
115neuronal ion channel clustering (GO:0045161)2.72655486
116detection of calcium ion (GO:0005513)2.72615649
117dendritic spine organization (GO:0097061)2.69214412
118regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.66907014
119neuromuscular process controlling balance (GO:0050885)2.66695650
120positive regulation of dendritic spine development (GO:0060999)2.62907837
121adenine nucleotide transport (GO:0051503)2.62482872
122regulation of dendritic spine morphogenesis (GO:0061001)2.60202405
123amino acid import (GO:0043090)2.57772759
124cell communication by electrical coupling (GO:0010644)2.53384333
125regulation of synaptic plasticity (GO:0048167)2.51784382
126positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.49846788
127protein insertion into membrane (GO:0051205)2.48837033
128neuromuscular synaptic transmission (GO:0007274)2.48210211
129proline metabolic process (GO:0006560)2.45688292
130heterochromatin organization (GO:0070828)2.42690980
131dicarboxylic acid transport (GO:0006835)2.42488771
132regulation of cholesterol biosynthetic process (GO:0045540)2.38148027
133purine nucleotide transport (GO:0015865)2.37953208
134protein retention in ER lumen (GO:0006621)2.37663496
135cytoskeletal anchoring at plasma membrane (GO:0007016)2.36760713
136protein-DNA complex disassembly (GO:0032986)2.36641901
137nucleosome disassembly (GO:0006337)2.36641901
138response to parathyroid hormone (GO:0071107)2.32615349
139membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.31818264
140ephrin receptor signaling pathway (GO:0048013)2.31611587
141paraxial mesoderm development (GO:0048339)2.30633941
142positive regulation of dendrite development (GO:1900006)2.30581645
143long-term memory (GO:0007616)2.30459570
144RNA localization (GO:0006403)2.30039707
145neuromuscular process controlling posture (GO:0050884)2.28867523
146establishment or maintenance of monopolar cell polarity (GO:0061339)2.27933566
147establishment of monopolar cell polarity (GO:0061162)2.27933566
148positive regulation of neurotransmitter transport (GO:0051590)2.27725757
149neurofilament cytoskeleton organization (GO:0060052)2.26129306
150protein complex localization (GO:0031503)2.25654752

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.94095943
2GBX2_23144817_ChIP-Seq_PC3_Human3.06189884
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.87085588
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.75901395
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.68719872
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.64127235
7REST_21632747_ChIP-Seq_MESCs_Mouse2.58744678
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.47999059
9ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.42241037
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.41138185
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.41138185
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.41094474
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.36743137
14SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26769487
15RNF2_27304074_Chip-Seq_ESCs_Mouse2.23109119
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.20544775
17TAF15_26573619_Chip-Seq_HEK293_Human2.17481332
18* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.16303306
19ESR1_15608294_ChIP-ChIP_MCF-7_Human2.15830553
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.15718397
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.13417013
22* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.13261077
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.09212364
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.09035157
25CTBP2_25329375_ChIP-Seq_LNCAP_Human2.08880449
26MTF2_20144788_ChIP-Seq_MESCs_Mouse2.08751139
27BMI1_23680149_ChIP-Seq_NPCS_Mouse2.08452164
28RNF2_27304074_Chip-Seq_NSC_Mouse2.01305400
29LXR_22292898_ChIP-Seq_THP-1_Human2.00552677
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.98208342
31ESR2_21235772_ChIP-Seq_MCF-7_Human1.96898235
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.91178755
33HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.90765312
34* KDM2B_26808549_Chip-Seq_K562_Human1.87812934
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.87324949
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.86811615
37IGF1R_20145208_ChIP-Seq_DFB_Human1.85085022
38BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.79176680
39* RACK7_27058665_Chip-Seq_MCF-7_Human1.78104063
40TET1_21451524_ChIP-Seq_MESCs_Mouse1.76896776
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.71604927
42CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.71118744
43* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.68525206
44* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.67493185
45RARB_27405468_Chip-Seq_BRAIN_Mouse1.66948355
46ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.64940389
47CTCF_27219007_Chip-Seq_Bcells_Human1.64857726
48CTBP1_25329375_ChIP-Seq_LNCAP_Human1.64404214
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.63845381
50TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63062875
51SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.61571401
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61362994
53ZFP57_27257070_Chip-Seq_ESCs_Mouse1.57842339
54ZNF274_21170338_ChIP-Seq_K562_Hela1.57802531
55DROSHA_22980978_ChIP-Seq_HELA_Human1.57430408
56CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.56014481
57EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55251022
58PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53785811
59MYC_18555785_ChIP-Seq_MESCs_Mouse1.53682563
60DNAJC2_21179169_ChIP-ChIP_NT2_Human1.53039697
61WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.53002953
62* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.50343303
63ZFP281_27345836_Chip-Seq_ESCs_Mouse1.50254335
64P68_20966046_ChIP-Seq_HELA_Human1.48795333
65ZNF263_19887448_ChIP-Seq_K562_Human1.48536413
66ESR1_21235772_ChIP-Seq_MCF-7_Human1.48504038
67SMAD4_21799915_ChIP-Seq_A2780_Human1.48222979
68GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48105261
69SRY_22984422_ChIP-ChIP_TESTIS_Rat1.47664969
70POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.46872079
71CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44118369
72CREB1_26743006_Chip-Seq_LNCaP_Human1.43589253
73XRN2_22483619_ChIP-Seq_HELA_Human1.42147410
74P300_19829295_ChIP-Seq_ESCs_Human1.41386933
75RING1B_27294783_Chip-Seq_ESCs_Mouse1.39683920
76SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37927941
77RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.36766228
78AR_21572438_ChIP-Seq_LNCaP_Human1.36517143
79EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.36511767
80TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35594106
81SMC4_20622854_ChIP-Seq_HELA_Human1.34503803
82CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.33654327
83* SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.33460209
84MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33217095
85MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.32075698
86VDR_22108803_ChIP-Seq_LS180_Human1.31838176
87POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.31497087
88TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31497087
89TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30584238
90TET1_21490601_ChIP-Seq_MESCs_Mouse1.30485266
91SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.29262788
92MYC_19079543_ChIP-ChIP_MESCs_Mouse1.29145099
93NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.29099944
94* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.24454568
95RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.24228662
96TP63_17297297_ChIP-ChIP_HaCaT_Human1.24029823
97ERG_21242973_ChIP-ChIP_JURKAT_Human1.23890833
98YY1_21170310_ChIP-Seq_MESCs_Mouse1.23721655
99DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.23716371
100SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22715386
101GATA1_26923725_Chip-Seq_HPCs_Mouse1.22573675
102SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21880832
103TP53_20018659_ChIP-ChIP_R1E_Mouse1.21079459
104* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21022792
105MYC_18358816_ChIP-ChIP_MESCs_Mouse1.19614465
106KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.19491713
107SMAD3_21741376_ChIP-Seq_EPCs_Human1.18981887
108SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.18448831
109SOX2_21211035_ChIP-Seq_LN229_Gbm1.18165373
110RING1B_27294783_Chip-Seq_NPCs_Mouse1.17386665
111OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.16643567
112ELK4_26923725_Chip-Seq_MESODERM_Mouse1.16604757
113* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.15447784
114TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15279029
115KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.14880469
116FOXP1_21924763_ChIP-Seq_HESCs_Human1.14199614
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12582962
118SA1_27219007_Chip-Seq_ERYTHROID_Human1.11591390
119SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.11225598
120CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.10841644
121NR3C1_23031785_ChIP-Seq_PC12_Mouse1.09372761
122KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09169604
123POU3F2_20337985_ChIP-ChIP_501MEL_Human1.08720225
124CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.08491364
125RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.07127200
126ZFX_18555785_ChIP-Seq_MESCs_Mouse1.06076666
127* KDM2B_26808549_Chip-Seq_DND41_Human1.05283177
128SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.05166308
129CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04625195
130RBPJ_22232070_ChIP-Seq_NCS_Mouse1.04561004
131POU5F1_16518401_ChIP-PET_MESCs_Mouse1.03998081
132AR_25329375_ChIP-Seq_VCAP_Human1.03783221
133FUS_26573619_Chip-Seq_HEK293_Human1.03265881
134ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.03076584
135CTCF_18555785_ChIP-Seq_MESCs_Mouse1.03031684
136STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.02787694
137DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.02302176
138FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.01563677
139STAT3_23295773_ChIP-Seq_U87_Human1.01224831
140SMAD3_21741376_ChIP-Seq_ESCs_Human1.00798667
141* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00727386
142RARA_24833708_ChIP-Seq_LIVER_Mouse1.00651615
143RUNX2_22187159_ChIP-Seq_PCA_Human1.00349958
144TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99316895
145PIAS1_25552417_ChIP-Seq_VCAP_Human0.96953263
146OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96846825
147* AR_19668381_ChIP-Seq_PC3_Human0.96630234
148P53_22127205_ChIP-Seq_FIBROBLAST_Human0.96121117
149AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95596507
150SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94541445
151ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94222774
152ARNT_22903824_ChIP-Seq_MCF-7_Human0.93707647
153UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93694015
154TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93010630
155AHR_22903824_ChIP-Seq_MCF-7_Human0.92653304
156YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92475780
157KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.92379427
158MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91929449
159PRDM14_20953172_ChIP-Seq_ESCs_Human0.90487166
160TCF4_23295773_ChIP-Seq_U87_Human0.89084900
161JUN_21703547_ChIP-Seq_K562_Human0.88178035
162SOX9_26525672_Chip-Seq_HEART_Mouse0.87701164
163TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87461036
164GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87397679
165NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85336353
166WT1_25993318_ChIP-Seq_PODOCYTE_Human0.85188918

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.60159474
2MP0004859_abnormal_synaptic_plasticity4.20760015
3MP0006276_abnormal_autonomic_nervous3.64680118
4MP0001984_abnormal_olfaction3.28590062
5MP0005423_abnormal_somatic_nervous3.18685042
6MP0003635_abnormal_synaptic_transmissio3.09415845
7MP0004270_analgesia2.97884398
8MP0000778_abnormal_nervous_system2.77198461
9MP0002063_abnormal_learning/memory/cond2.67230199
10MP0001968_abnormal_touch/_nociception2.62291791
11MP0002734_abnormal_mechanical_nocicepti2.54804909
12MP0009745_abnormal_behavioral_response2.42856738
13MP0009046_muscle_twitch2.39243169
14MP0002572_abnormal_emotion/affect_behav2.34703993
15MP0001529_abnormal_vocalization2.33769378
16MP0002184_abnormal_innervation2.32876533
17MP0002736_abnormal_nociception_after2.29596725
18MP0002064_seizures2.26711022
19MP0002733_abnormal_thermal_nociception2.08625915
20MP0000566_synostosis2.08093673
21MP0003122_maternal_imprinting2.04850837
22MP0005646_abnormal_pituitary_gland1.96550282
23MP0002272_abnormal_nervous_system1.96064969
24MP0002735_abnormal_chemical_nociception1.94273238
25MP0001486_abnormal_startle_reflex1.93387003
26MP0001970_abnormal_pain_threshold1.90736813
27MP0005645_abnormal_hypothalamus_physiol1.89845814
28MP0005499_abnormal_olfactory_system1.88781918
29MP0005394_taste/olfaction_phenotype1.88781918
30MP0004858_abnormal_nervous_system1.83169036
31MP0002653_abnormal_ependyma_morphology1.80266586
32MP0002557_abnormal_social/conspecific_i1.76470830
33MP0002067_abnormal_sensory_capabilities1.75971376
34MP0008789_abnormal_olfactory_epithelium1.73364323
35MP0001905_abnormal_dopamine_level1.72309429
36MP0004811_abnormal_neuron_physiology1.72022861
37MP0003787_abnormal_imprinting1.71939312
38MP0001440_abnormal_grooming_behavior1.71077108
39MP0000955_abnormal_spinal_cord1.66564571
40MP0002249_abnormal_larynx_morphology1.62846392
41MP0002102_abnormal_ear_morphology1.58964461
42MP0001501_abnormal_sleep_pattern1.57077409
43MP0001346_abnormal_lacrimal_gland1.54116160
44MP0002882_abnormal_neuron_morphology1.53161200
45MP0010030_abnormal_orbit_morphology1.52377596
46MP0005386_behavior/neurological_phenoty1.51567052
47MP0004924_abnormal_behavior1.51567052
48MP0003121_genomic_imprinting1.47173259
49MP0003646_muscle_fatigue1.42450731
50MP0009672_abnormal_birth_weight1.36930095
51MP0002909_abnormal_adrenal_gland1.34943053
52MP0002152_abnormal_brain_morphology1.34739936
53MP0000537_abnormal_urethra_morphology1.34721593
54MP0000631_abnormal_neuroendocrine_gland1.34715168
55MP0009780_abnormal_chondrocyte_physiolo1.33004392
56MP0002066_abnormal_motor_capabilities/c1.24165785
57MP0004233_abnormal_muscle_weight1.22075052
58MP0002638_abnormal_pupillary_reflex1.21683678
59MP0002822_catalepsy1.21021775
60MP0003329_amyloid_beta_deposits1.20241206
61MP0002752_abnormal_somatic_nervous1.19207413
62MP0003861_abnormal_nervous_system1.15423344
63MP0003879_abnormal_hair_cell1.15381417
64MP0001502_abnormal_circadian_rhythm1.13225751
65MP0000579_abnormal_nail_morphology1.11964531
66MP0003705_abnormal_hypodermis_morpholog1.11496136
67MP0004142_abnormal_muscle_tone1.07941611
68MP0004133_heterotaxia1.07862703
69MP0003119_abnormal_digestive_system1.07228613
70MP0008569_lethality_at_weaning1.06882569
71MP0002837_dystrophic_cardiac_calcinosis1.06797009
72MP0002751_abnormal_autonomic_nervous1.06514323
73MP0002089_abnormal_postnatal_growth/wei1.06289978
74MP0000569_abnormal_digit_pigmentation1.06189812
75MP0004742_abnormal_vestibular_system1.06159118
76MP0006072_abnormal_retinal_apoptosis1.06109332
77MP0000751_myopathy1.05976633
78MP0005410_abnormal_fertilization1.05572230
79MP0010386_abnormal_urinary_bladder1.05395514
80MP0006292_abnormal_olfactory_placode1.04043125
81MP0001348_abnormal_lacrimal_gland1.03752954
82MP0008877_abnormal_DNA_methylation1.01196162
83MP0005551_abnormal_eye_electrophysiolog0.95448399
84MP0000049_abnormal_middle_ear0.93667552
85MP0003698_abnormal_male_reproductive0.92738182
86MP0004885_abnormal_endolymph0.87211124
87MP0000462_abnormal_digestive_system0.87060100
88MP0004145_abnormal_muscle_electrophysio0.86552053
89MP0002069_abnormal_eating/drinking_beha0.85444741
90MP0001849_ear_inflammation0.83855824
91MP0001188_hyperpigmentation0.82741246
92MP0003941_abnormal_skin_development0.82741070
93MP0000026_abnormal_inner_ear0.82165494
94MP0002697_abnormal_eye_size0.82126729
95MP0005377_hearing/vestibular/ear_phenot0.82064113
96MP0003878_abnormal_ear_physiology0.82064113
97MP0000678_abnormal_parathyroid_gland0.81153599
98MP0000538_abnormal_urinary_bladder0.80503208
99MP0001485_abnormal_pinna_reflex0.79972746
100MP0005187_abnormal_penis_morphology0.79397798
101MP0001963_abnormal_hearing_physiology0.78199605
102MP0002229_neurodegeneration0.76668717
103MP0003890_abnormal_embryonic-extraembry0.76453787
104MP0003693_abnormal_embryo_hatching0.75294973
105MP0001299_abnormal_eye_distance/0.74888322
106MP0000534_abnormal_ureter_morphology0.74385244
107MP0002163_abnormal_gland_morphology0.73712278
108MP0003937_abnormal_limbs/digits/tail_de0.73357367
109MP0005409_darkened_coat_color0.72885543
110MP0003115_abnormal_respiratory_system0.71644344
111MP0002161_abnormal_fertility/fecundity0.71115879
112MP0000003_abnormal_adipose_tissue0.70695307
113MP0003634_abnormal_glial_cell0.70379330
114MP0001929_abnormal_gametogenesis0.70251818
115MP0003283_abnormal_digestive_organ0.70083469
116MP0003137_abnormal_impulse_conducting0.69939263
117MP0002796_impaired_skin_barrier0.69824480
118MP0003315_abnormal_perineum_morphology0.69271917
119MP0010234_abnormal_vibrissa_follicle0.69215717
120MP0005623_abnormal_meninges_morphology0.68863287
121MP0002081_perinatal_lethality0.68338561
122MP0002233_abnormal_nose_morphology0.68256320
123MP0003123_paternal_imprinting0.67870361
124MP0003385_abnormal_body_wall0.66884925
125MP0003942_abnormal_urinary_system0.66721468
126MP0003631_nervous_system_phenotype0.66402436
127MP0001943_abnormal_respiration0.66309198
128MP0002254_reproductive_system_inflammat0.64732026
129MP0008872_abnormal_physiological_respon0.64473731
130MP0004085_abnormal_heartbeat0.63574488
131MP0008995_early_reproductive_senescence0.62590655
132MP0003938_abnormal_ear_development0.61099505
133MP0003632_abnormal_nervous_system0.59265291
134MP0002210_abnormal_sex_determination0.59256332
135MP0005253_abnormal_eye_physiology0.58335853

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.99406592
2Focal motor seizures (HP:0011153)4.52693150
3Limb dystonia (HP:0002451)4.25254326
4Polyphagia (HP:0002591)4.23354978
5Focal seizures (HP:0007359)4.05094228
6Supranuclear gaze palsy (HP:0000605)4.00105454
7Progressive cerebellar ataxia (HP:0002073)3.78330075
8Failure to thrive in infancy (HP:0001531)3.75571712
9Febrile seizures (HP:0002373)3.59046455
10Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.55111010
11Atonic seizures (HP:0010819)3.51438799
12Abnormal eating behavior (HP:0100738)3.40055636
13Visual hallucinations (HP:0002367)3.38659533
14Epileptic encephalopathy (HP:0200134)3.29175162
15Abnormality of the labia minora (HP:0012880)3.08841346
16Abnormal respiratory motile cilium physiology (HP:0012261)3.01908379
17Hepatoblastoma (HP:0002884)2.99093788
18Gait imbalance (HP:0002141)2.96100745
19Hyperacusis (HP:0010780)2.91473962
20Amblyopia (HP:0000646)2.84762174
21Absence seizures (HP:0002121)2.84354936
22Esotropia (HP:0000565)2.79846366
23Insomnia (HP:0100785)2.74909650
24Abnormal ciliary motility (HP:0012262)2.74075291
25Abnormal hair whorl (HP:0010721)2.73481848
26Fetal akinesia sequence (HP:0001989)2.69921160
27Termporal pattern (HP:0011008)2.66904289
28Insidious onset (HP:0003587)2.66904289
29Impaired vibration sensation in the lower limbs (HP:0002166)2.64851360
30Pheochromocytoma (HP:0002666)2.60277571
31Medial flaring of the eyebrow (HP:0010747)2.59068597
32Generalized tonic-clonic seizures (HP:0002069)2.56564055
33Specific learning disability (HP:0001328)2.53799769
34Dialeptic seizures (HP:0011146)2.52092028
35Infertility (HP:0000789)2.49584884
36Mutism (HP:0002300)2.48425711
37Rhinitis (HP:0012384)2.48254712
38Abnormal respiratory epithelium morphology (HP:0012253)2.47354643
39Abnormal respiratory motile cilium morphology (HP:0005938)2.47354643
40Dynein arm defect of respiratory motile cilia (HP:0012255)2.47080960
41Absent/shortened dynein arms (HP:0200106)2.47080960
42Aplasia/Hypoplasia of the brainstem (HP:0007362)2.43010153
43Hypoplasia of the brainstem (HP:0002365)2.43010153
44Agitation (HP:0000713)2.41023274
45Congenital primary aphakia (HP:0007707)2.40406022
46Neuroendocrine neoplasm (HP:0100634)2.40238647
47Abnormality of the corticospinal tract (HP:0002492)2.38628293
48Anosmia (HP:0000458)2.37702293
49Broad-based gait (HP:0002136)2.37001475
50Action tremor (HP:0002345)2.32505416
51Ankle clonus (HP:0011448)2.31451376
52Urinary bladder sphincter dysfunction (HP:0002839)2.31366749
53Truncal ataxia (HP:0002078)2.30101980
54Excessive salivation (HP:0003781)2.27776249
55Drooling (HP:0002307)2.27776249
56Septate vagina (HP:0001153)2.26076741
57EEG with generalized epileptiform discharges (HP:0011198)2.25766312
58Exotropia (HP:0000577)2.25227708
59Progressive inability to walk (HP:0002505)2.24244815
60Epileptiform EEG discharges (HP:0011182)2.23935079
61Retinal dysplasia (HP:0007973)2.23746981
62Amyotrophic lateral sclerosis (HP:0007354)2.23448567
63Bronchomalacia (HP:0002780)2.22823474
64Urinary urgency (HP:0000012)2.22023788
65Overriding aorta (HP:0002623)2.19507022
66Genital tract atresia (HP:0001827)2.19316050
67Nephrogenic diabetes insipidus (HP:0009806)2.18033895
68Hypsarrhythmia (HP:0002521)2.16752674
69Atelectasis (HP:0100750)2.15865156
70Broad distal phalanx of finger (HP:0009836)2.15394616
71Poor suck (HP:0002033)2.13911760
72Spastic gait (HP:0002064)2.13646905
73Turricephaly (HP:0000262)2.13449588
74Cerebral hypomyelination (HP:0006808)2.13382294
75Shoulder girdle muscle weakness (HP:0003547)2.12770970
76Vaginal atresia (HP:0000148)2.12363308
77Hypoventilation (HP:0002791)2.12030049
78Lissencephaly (HP:0001339)2.11357587
79Molar tooth sign on MRI (HP:0002419)2.10354912
80Abnormality of midbrain morphology (HP:0002418)2.10354912
81Distal upper limb amyotrophy (HP:0007149)2.09528087
82Upper limb amyotrophy (HP:0009129)2.09528087
83Sleep apnea (HP:0010535)2.09128697
84Hand muscle atrophy (HP:0009130)2.09031477
85Elfin facies (HP:0004428)2.08891795
86Abnormality of the lower motor neuron (HP:0002366)2.07967000
87Torticollis (HP:0000473)2.07708328
88Abnormality of the aortic arch (HP:0012303)2.07500353
89Long palpebral fissure (HP:0000637)2.06602739
90Choanal stenosis (HP:0000452)2.04490147
91Status epilepticus (HP:0002133)2.02708523
92Aplasia/Hypoplasia of the lens (HP:0008063)2.01416876
93Narrow nasal bridge (HP:0000446)2.00282754
94Morphological abnormality of the inner ear (HP:0011390)1.99431911
95Gaze-evoked nystagmus (HP:0000640)1.99122653
96Focal dystonia (HP:0004373)1.98175867
97Enlarged penis (HP:0000040)1.97793274
98Papillary thyroid carcinoma (HP:0002895)1.94520160
99Abnormality of cochlea (HP:0000375)1.94367610
100Obstructive sleep apnea (HP:0002870)1.93546994
101Pointed chin (HP:0000307)1.93378903
102Hypothermia (HP:0002045)1.92891101
103Hemiparesis (HP:0001269)1.92293947
104Lower limb muscle weakness (HP:0007340)1.91470439
105High anterior hairline (HP:0009890)1.87888089
106Depression (HP:0000716)1.87664568
107Double outlet right ventricle (HP:0001719)1.86639049
108Congenital malformation of the right heart (HP:0011723)1.86639049
109Anxiety (HP:0000739)1.86124403
110Germ cell neoplasia (HP:0100728)1.85800121
111Generalized hypotonia (HP:0001290)1.85003359
112Craniofacial dystonia (HP:0012179)1.84891380
113Hyperthyroidism (HP:0000836)1.84627699
114Peripheral hypomyelination (HP:0007182)1.84484073
115Narrow forehead (HP:0000341)1.83586998
116Annular pancreas (HP:0001734)1.82785353
117Male infertility (HP:0003251)1.82503270
118Increased nuchal translucency (HP:0010880)1.81149413
119Akinesia (HP:0002304)1.81090799
120Hyperventilation (HP:0002883)1.80652792
121Neoplasm of the peripheral nervous system (HP:0100007)1.77486895
122Morphological abnormality of the pyramidal tract (HP:0002062)1.76071287
123Degeneration of the lateral corticospinal tracts (HP:0002314)1.75872450
124Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.75872450
125Dysmetria (HP:0001310)1.75185051
126Dysdiadochokinesis (HP:0002075)1.75147193
127Abnormality of macular pigmentation (HP:0008002)1.74887875
128Neoplasm of the adrenal cortex (HP:0100641)1.74579676
129Lower limb amyotrophy (HP:0007210)1.73876945
130Aplasia involving bones of the upper limbs (HP:0009823)1.72406067
131Aplasia of the phalanges of the hand (HP:0009802)1.72406067
132Aplasia involving bones of the extremities (HP:0009825)1.72406067
133Abnormal social behavior (HP:0012433)1.72277412
134Impaired social interactions (HP:0000735)1.72277412
135Precocious puberty (HP:0000826)1.72258719
136Concave nail (HP:0001598)1.70421070
137Cholecystitis (HP:0001082)1.69842187
138Abnormal gallbladder physiology (HP:0012438)1.69842187
139Nephronophthisis (HP:0000090)1.69755209
140Myopathic facies (HP:0002058)1.67299935
141Renal duplication (HP:0000075)1.66023007
142Diastasis recti (HP:0001540)1.65889847
143Bicornuate uterus (HP:0000813)1.64961499
144Megalencephaly (HP:0001355)1.63428834
145Truncus arteriosus (HP:0001660)1.63364813
146Poor eye contact (HP:0000817)1.62578325
147Restlessness (HP:0000711)1.61111542
148Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.59988928
149Shallow orbits (HP:0000586)1.59531455
150Deep palmar crease (HP:0006191)1.55038454
151Deep venous thrombosis (HP:0002625)1.54825410
152Hyperparathyroidism (HP:0000843)1.53841925
153Arnold-Chiari malformation (HP:0002308)1.53718646
154Microglossia (HP:0000171)1.52986504
155Asymmetry of the thorax (HP:0001555)1.51808108
156Nasal speech (HP:0001611)1.49627802
157Athetosis (HP:0002305)1.48544508
158Asymmetric growth (HP:0100555)1.48441726
159Partial duplication of thumb phalanx (HP:0009944)1.47055862
160Hypercalcemia (HP:0003072)1.46296272

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.24963807
2TRIB33.82980344
3MAP3K93.71036807
4MAP3K43.15472493
5NTRK32.68249414
6NTRK22.64768003
7MAP2K72.51319880
8SIK12.45011017
9MAPK132.44730015
10SMG12.42803458
11MINK12.29863190
12PAK62.29664534
13DYRK22.22362368
14PNCK2.21200233
15KSR12.10590820
16EPHA22.10505962
17CASK2.02563345
18MAP3K121.95063502
19ARAF1.93044727
20KSR21.83899867
21SIK21.77695455
22CAMKK21.77073142
23CAMK1G1.76631369
24MAP2K41.70738771
25EPHA41.68509373
26PKN21.62006023
27MAP3K61.60256843
28GRK51.45844740
29PHKG21.44869023
30PHKG11.44869023
31VRK21.44321054
32WNK31.43757304
33LATS21.43332808
34PRKD31.42471173
35UHMK11.41316510
36CSNK1G21.36913805
37PLK21.34730501
38BRSK11.32767467
39NME21.30444149
40BRAF1.30324266
41CSNK1G31.29106266
42SIK31.25990130
43CAMK1D1.25019408
44TESK11.23963258
45CDK51.18964705
46DAPK21.13685208
47TYRO31.11184616
48RPS6KB21.10769539
49CAMKK11.09704484
50STK161.08421448
51FGFR41.07379874
52NME11.04090507
53PRPF4B1.03238034
54NTRK11.01243685
55PRKCI1.00576864
56SGK4940.95979831
57SGK2230.95979831
58CDK180.94111992
59PRKCG0.91121043
60PAK30.90132177
61BCR0.89413679
62CAMK2A0.88860438
63CSNK1G10.87380861
64CDK150.86786227
65EPHB20.86123913
66DYRK1A0.85984847
67ICK0.85820733
68ALK0.85794692
69MAP3K110.85111995
70CDK140.84898271
71LIMK10.84269076
72PTK20.84012381
73RPS6KA20.80439583
74DYRK1B0.78406882
75CSNK1A1L0.77693476
76ERBB30.77399639
77ERBB40.76857912
78MOS0.75923582
79TAOK10.74663820
80MARK20.74453091
81CDK11A0.72275119
82BMPR20.72101088
83RET0.71968167
84SRPK10.70929259
85FGFR20.70524117
86MAP3K100.69786310
87IRAK30.69003637
88AKT20.68735103
89MTOR0.68089601
90RIPK10.67811901
91TAF10.67095444
92STK380.66937322
93MAP2K20.66908841
94EEF2K0.63199138
95CDC70.62902001
96SGK20.62670940
97NEK60.62557366
98CAMK2B0.61913025
99DAPK30.60940403
100PRKCH0.60053082
101MUSK0.59310148
102ILK0.59195324
103RAF10.58826311
104MAP3K130.58773645
105PTK60.58487318
106STK110.58305695
107CDK190.57766508
108CDK70.57566309
109ADRBK10.57539773
110DAPK10.55104773
111PRKCZ0.55039887
112MAPKAPK30.53913239
113TESK20.52801429
114WNK40.52757505
115BMPR1B0.50419033
116ROCK20.48851997
117PLK30.48407898
118IRAK20.47935452
119TTK0.47551339
120DYRK30.46888544
121PDPK10.46721750
122CDK120.46400417
123CHEK20.45691837
124PAK40.44854281
125ROCK10.39361345
126TNIK0.39278619
127GRK70.38556662
128CCNB10.38349084
129LMTK20.37777794
130MAPK90.37300200
131CAMK40.37189660
132CAMK10.36249063
133CAMK2G0.35862498
134AURKA0.35305470
135CDK80.35149666
136CSNK1E0.33732105
137PKN10.32622417
138RIPK40.32217120
139MAP2K10.31999105
140PRKCE0.31218413
141FGR0.29700220
142MAPK100.29678253
143MAPKAPK50.29465548

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.72165502
2Synaptic vesicle cycle_Homo sapiens_hsa047213.42585005
3Olfactory transduction_Homo sapiens_hsa047403.18053359
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.59169685
5GABAergic synapse_Homo sapiens_hsa047272.55646708
6Vitamin B6 metabolism_Homo sapiens_hsa007502.43429176
7Glutamatergic synapse_Homo sapiens_hsa047242.33900522
8Dopaminergic synapse_Homo sapiens_hsa047282.33254787
9Circadian entrainment_Homo sapiens_hsa047132.31077822
10Morphine addiction_Homo sapiens_hsa050322.30132008
11Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.19075312
12Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.18547858
13Taste transduction_Homo sapiens_hsa047422.14954775
14Sulfur relay system_Homo sapiens_hsa041222.12428474
15Serotonergic synapse_Homo sapiens_hsa047262.05582264
162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.04911115
17Cholinergic synapse_Homo sapiens_hsa047251.95260573
18Collecting duct acid secretion_Homo sapiens_hsa049661.91905193
19Long-term potentiation_Homo sapiens_hsa047201.91531681
20Amphetamine addiction_Homo sapiens_hsa050311.88487035
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.81969675
22Cocaine addiction_Homo sapiens_hsa050301.81608109
23Insulin secretion_Homo sapiens_hsa049111.78594085
24Axon guidance_Homo sapiens_hsa043601.77110948
25Biosynthesis of amino acids_Homo sapiens_hsa012301.74523661
26Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.60360543
27Long-term depression_Homo sapiens_hsa047301.59182076
28Gap junction_Homo sapiens_hsa045401.52440752
29Salivary secretion_Homo sapiens_hsa049701.52422533
30GnRH signaling pathway_Homo sapiens_hsa049121.48716705
31Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.47834115
32Cardiac muscle contraction_Homo sapiens_hsa042601.43691323
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.42104616
34Oocyte meiosis_Homo sapiens_hsa041141.38094249
35Gastric acid secretion_Homo sapiens_hsa049711.36588052
36Arginine and proline metabolism_Homo sapiens_hsa003301.34586594
37Oxytocin signaling pathway_Homo sapiens_hsa049211.34071230
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.32866143
39Renin secretion_Homo sapiens_hsa049241.32466641
40Oxidative phosphorylation_Homo sapiens_hsa001901.24011360
41Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.23047000
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20321472
43Steroid biosynthesis_Homo sapiens_hsa001001.20034659
44Calcium signaling pathway_Homo sapiens_hsa040201.19661727
45Parkinsons disease_Homo sapiens_hsa050121.16917890
46Estrogen signaling pathway_Homo sapiens_hsa049151.14729985
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.10103029
48Phototransduction_Homo sapiens_hsa047441.08266795
49Huntingtons disease_Homo sapiens_hsa050161.07829399
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.07716292
51Central carbon metabolism in cancer_Homo sapiens_hsa052301.07048695
52Vibrio cholerae infection_Homo sapiens_hsa051101.06442047
53ErbB signaling pathway_Homo sapiens_hsa040121.06234949
54Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04348842
55Arginine biosynthesis_Homo sapiens_hsa002201.03574316
56Alzheimers disease_Homo sapiens_hsa050101.03113900
57Carbon metabolism_Homo sapiens_hsa012001.00687712
58Tight junction_Homo sapiens_hsa045301.00225929
59Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.99639551
60Ribosome_Homo sapiens_hsa030100.99195727
61Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98101743
62AMPK signaling pathway_Homo sapiens_hsa041520.97621732
63Melanogenesis_Homo sapiens_hsa049160.97499354
64cAMP signaling pathway_Homo sapiens_hsa040240.94375219
65Alcoholism_Homo sapiens_hsa050340.94251770
66Dorso-ventral axis formation_Homo sapiens_hsa043200.91704820
67Colorectal cancer_Homo sapiens_hsa052100.90995258
68Ovarian steroidogenesis_Homo sapiens_hsa049130.90277910
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.88877244
70Basal cell carcinoma_Homo sapiens_hsa052170.88675040
71Endometrial cancer_Homo sapiens_hsa052130.88357079
72Pentose phosphate pathway_Homo sapiens_hsa000300.87406692
73Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.84953197
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.84770589
75Notch signaling pathway_Homo sapiens_hsa043300.84540337
76Glioma_Homo sapiens_hsa052140.84529096
77Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.83162780
78Type II diabetes mellitus_Homo sapiens_hsa049300.81855989
79Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81047788
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.79862760
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.77738717
82Thyroid cancer_Homo sapiens_hsa052160.77429435
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77039578
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75788824
85Fructose and mannose metabolism_Homo sapiens_hsa000510.75522063
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75151593
87Lysine degradation_Homo sapiens_hsa003100.68897441
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.68442949
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.68273017
90MAPK signaling pathway_Homo sapiens_hsa040100.68075898
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.67578159
92Renal cell carcinoma_Homo sapiens_hsa052110.65770913
93Choline metabolism in cancer_Homo sapiens_hsa052310.65224476
94Bile secretion_Homo sapiens_hsa049760.65098791
95Ras signaling pathway_Homo sapiens_hsa040140.65070388
96Wnt signaling pathway_Homo sapiens_hsa043100.61380371
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60659922
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60496864
99Circadian rhythm_Homo sapiens_hsa047100.60178161
100Dilated cardiomyopathy_Homo sapiens_hsa054140.59879942
101Phenylalanine metabolism_Homo sapiens_hsa003600.59712975
102Hedgehog signaling pathway_Homo sapiens_hsa043400.59356241
103Insulin signaling pathway_Homo sapiens_hsa049100.58249072
104Galactose metabolism_Homo sapiens_hsa000520.57999166
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57570285
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.57221382
107Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56193105
108Glucagon signaling pathway_Homo sapiens_hsa049220.54874523
109mTOR signaling pathway_Homo sapiens_hsa041500.53121361
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52455708
111Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.52277373
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52010703
113Base excision repair_Homo sapiens_hsa034100.51236422
114VEGF signaling pathway_Homo sapiens_hsa043700.50590831
115DNA replication_Homo sapiens_hsa030300.48877827
116Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48824373
117Inositol phosphate metabolism_Homo sapiens_hsa005620.48312923
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47378943
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46740692
120Non-small cell lung cancer_Homo sapiens_hsa052230.46216037
121mRNA surveillance pathway_Homo sapiens_hsa030150.44728367
122Prion diseases_Homo sapiens_hsa050200.43576460
123Rap1 signaling pathway_Homo sapiens_hsa040150.41992616
124Hippo signaling pathway_Homo sapiens_hsa043900.38625736
125Thyroid hormone synthesis_Homo sapiens_hsa049180.38503774
126Pancreatic secretion_Homo sapiens_hsa049720.37022853
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.36879594
128Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36511141
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36229525
130Phagosome_Homo sapiens_hsa041450.35364058
131Prolactin signaling pathway_Homo sapiens_hsa049170.34399008
132Ether lipid metabolism_Homo sapiens_hsa005650.31994911
133Pyruvate metabolism_Homo sapiens_hsa006200.31841182
134Endocytosis_Homo sapiens_hsa041440.31768374

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