DCBLD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)5.95123127
2keratinocyte proliferation (GO:0043616)4.39354045
3membrane raft organization (GO:0031579)4.37099575
4positive regulation of vesicle fusion (GO:0031340)4.28200874
5protein heterotetramerization (GO:0051290)4.25359536
6cellular response to vitamin D (GO:0071305)4.16362601
7regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.11749926
8chondrocyte proliferation (GO:0035988)4.11363604
9hepatocyte differentiation (GO:0070365)4.07426467
10protein localization to endosome (GO:0036010)3.82421705
11axon extension involved in axon guidance (GO:0048846)3.76397113
12neuron projection extension involved in neuron projection guidance (GO:1902284)3.76397113
13collagen fibril organization (GO:0030199)3.74454315
14cell adhesion mediated by integrin (GO:0033627)3.71987035
15cellular response to vitamin (GO:0071295)3.65774723
16skin morphogenesis (GO:0043589)3.63890157
17negative regulation of axon extension involved in axon guidance (GO:0048843)3.57582845
18muscle cell migration (GO:0014812)3.53021043
19endothelial cell morphogenesis (GO:0001886)3.46617273
20response to X-ray (GO:0010165)3.43599527
21mitotic metaphase plate congression (GO:0007080)3.38954428
22protein hydroxylation (GO:0018126)3.35943797
23regulation of mitotic spindle organization (GO:0060236)3.30524314
24desmosome organization (GO:0002934)3.29182982
25wound healing, spreading of epidermal cells (GO:0035313)3.26662775
26hippo signaling (GO:0035329)3.26060431
27paraxial mesoderm development (GO:0048339)3.23772790
28hypotonic response (GO:0006971)3.18689916
29negative regulation of DNA repair (GO:0045738)3.17424806
30metaphase plate congression (GO:0051310)3.16912653
31UDP-N-acetylglucosamine metabolic process (GO:0006047)3.15446042
32metanephric mesenchyme development (GO:0072075)3.12239244
33establishment of chromosome localization (GO:0051303)3.10957688
34ribosome assembly (GO:0042255)3.05605051
35sequestering of extracellular ligand from receptor (GO:0035581)3.01514208
36membrane budding (GO:0006900)3.00662569
37establishment of integrated proviral latency (GO:0075713)2.99193455
38mesenchymal-epithelial cell signaling (GO:0060638)2.95810645
39kidney mesenchyme development (GO:0072074)2.95108308
40ganglion development (GO:0061548)2.93982041
41ventricular cardiac muscle cell development (GO:0055015)2.93720618
42mitotic cytokinesis (GO:0000281)2.93564198
43cell-substrate junction assembly (GO:0007044)2.93177879
44cell migration involved in sprouting angiogenesis (GO:0002042)2.92909159
45endodermal cell differentiation (GO:0035987)2.91752581
46negative regulation of chondrocyte differentiation (GO:0032331)2.91472885
47cytoskeleton-dependent cytokinesis (GO:0061640)2.87071115
48facial nerve structural organization (GO:0021612)2.87032448
49regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.86576180
50protein heterotrimerization (GO:0070208)2.85901384
51positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.85406156
52mesodermal cell differentiation (GO:0048333)2.81416052
53negative regulation of axon guidance (GO:1902668)2.79046266
54mitotic sister chromatid segregation (GO:0000070)2.78967476
55COPI coating of Golgi vesicle (GO:0048205)2.77023337
56Golgi transport vesicle coating (GO:0048200)2.77023337
57mammary gland epithelial cell proliferation (GO:0033598)2.76856254
58regulation of spindle organization (GO:0090224)2.76657252
59retina vasculature morphogenesis in camera-type eye (GO:0061299)2.76274571
60membrane assembly (GO:0071709)2.75368809
61negative regulation of keratinocyte proliferation (GO:0010839)2.72843483
62nuclear pore complex assembly (GO:0051292)2.71756246
63positive regulation of heat generation (GO:0031652)2.70253761
64lipopolysaccharide biosynthetic process (GO:0009103)2.70135995
65regulation of epidermal growth factor-activated receptor activity (GO:0007176)2.69412750
66sister chromatid segregation (GO:0000819)2.68556234
67nucleobase-containing small molecule interconversion (GO:0015949)2.67069278
68basement membrane organization (GO:0071711)2.67003913
69histone-serine phosphorylation (GO:0035404)2.64595106
70dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.64495785
71bone trabecula formation (GO:0060346)2.63915427
72cartilage morphogenesis (GO:0060536)2.63662790
73protein localization to kinetochore (GO:0034501)2.63218445
74nucleotide-sugar biosynthetic process (GO:0009226)2.61859533
75planar cell polarity pathway involved in neural tube closure (GO:0090179)2.61508258
76proteasome assembly (GO:0043248)2.60962735
77chondrocyte development (GO:0002063)2.59753210
78insulin-like growth factor receptor signaling pathway (GO:0048009)2.57087325
79mitotic sister chromatid cohesion (GO:0007064)2.56215355
80protein localization to cell surface (GO:0034394)2.55301556
81face morphogenesis (GO:0060325)2.54771699
82regulation of fever generation (GO:0031620)2.53267944
83regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.52819238
84negative regulation of anoikis (GO:2000811)2.52518224
85cellular response to interferon-alpha (GO:0035457)2.52054753
86regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.50919995
87protein localization to chromosome, centromeric region (GO:0071459)2.50898626
88regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.50826637
89pericardium development (GO:0060039)2.50789573
90craniofacial suture morphogenesis (GO:0097094)2.50633868
91mitotic chromosome condensation (GO:0007076)2.49565138
92plasma membrane repair (GO:0001778)2.49330695
93positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.47127607
94fibroblast migration (GO:0010761)2.47102439
95activation of Rac GTPase activity (GO:0032863)2.46349484
96positive regulation of cytokinesis (GO:0032467)2.45940645
97negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.44394506
98substrate adhesion-dependent cell spreading (GO:0034446)2.43897503
99regulation of integrin activation (GO:0033623)2.43325741
100substrate-dependent cell migration (GO:0006929)2.42755853
101notochord development (GO:0030903)2.42173917
102positive regulation of protein autophosphorylation (GO:0031954)2.41631833
103lymphangiogenesis (GO:0001946)2.41478081
104semaphorin-plexin signaling pathway (GO:0071526)2.40804627
105nuclear pore organization (GO:0006999)2.39712456
106apoptotic cell clearance (GO:0043277)2.38837501
107embryonic cranial skeleton morphogenesis (GO:0048701)2.38422602
108peptidyl-proline hydroxylation (GO:0019511)2.37468967
109positive regulation of actin filament depolymerization (GO:0030836)2.36102622
110wound healing, spreading of cells (GO:0044319)2.35826493
111SMAD protein complex assembly (GO:0007183)2.35782411
112regulation of axon extension involved in axon guidance (GO:0048841)2.34941271
113bone remodeling (GO:0046849)2.34940703
114neural crest cell development (GO:0014032)2.34852394
115mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.34485098
116positive regulation of male gonad development (GO:2000020)2.33931524
117negative regulation of fatty acid transport (GO:2000192)2.32786428
118morphogenesis of an epithelial sheet (GO:0002011)2.31767494
119collagen catabolic process (GO:0030574)2.31686976
120branching involved in salivary gland morphogenesis (GO:0060445)2.31600191
121glomerular visceral epithelial cell development (GO:0072015)2.31474090
122renal filtration (GO:0097205)2.31313602
123atrial septum morphogenesis (GO:0060413)2.31178674
124tight junction assembly (GO:0070830)2.31062239
125heart morphogenesis (GO:0003007)2.30862149
126negative regulation of stem cell proliferation (GO:2000647)2.30701236
127collagen metabolic process (GO:0032963)2.30690448
128regulation of protein export from nucleus (GO:0046825)2.30256528
129fibrinolysis (GO:0042730)2.30220276
130cellular protein complex localization (GO:0034629)2.29560311
131regulation of centriole replication (GO:0046599)2.29498792
132negative regulation of cartilage development (GO:0061037)2.29410987
133positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.28979744
134positive regulation vascular endothelial growth factor production (GO:0010575)2.28564723
135positive regulation of establishment of protein localization to plasma membrane (GO:0090004)2.26587992
136lateral sprouting from an epithelium (GO:0060601)2.26499455
137smooth muscle tissue development (GO:0048745)2.26226284
138dorsal/ventral axis specification (GO:0009950)2.25640416
139regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.24532570
140regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.24343387
141negative chemotaxis (GO:0050919)2.23695154
142epithelial to mesenchymal transition (GO:0001837)2.23600236
143negative regulation of catenin import into nucleus (GO:0035414)2.22577467
144iron ion import (GO:0097286)2.20068081
145regulation of heart morphogenesis (GO:2000826)2.19667550
146cytoplasmic mRNA processing body assembly (GO:0033962)2.19476916
147pore complex assembly (GO:0046931)2.19302689
148mesenchyme development (GO:0060485)2.18748224
149extracellular matrix disassembly (GO:0022617)2.17389607
150regulation of SMAD protein import into nucleus (GO:0060390)2.17128992
151head development (GO:0060322)2.17044596
152glomerular basement membrane development (GO:0032836)2.16995109
153anatomical structure arrangement (GO:0048532)2.16857390
154germ cell migration (GO:0008354)2.16659788
155embryonic forelimb morphogenesis (GO:0035115)2.16657382
156embryonic camera-type eye development (GO:0031076)2.16431746
157regulation of keratinocyte proliferation (GO:0010837)2.16096340
158regulation of transforming growth factor beta2 production (GO:0032909)2.15376174
159regulation of tight junction assembly (GO:2000810)2.15283244
160multicellular organismal macromolecule metabolic process (GO:0044259)2.15217701
161embryonic skeletal joint morphogenesis (GO:0060272)2.13955414
162positive regulation of SMAD protein import into nucleus (GO:0060391)2.13764230
163regulation of chondrocyte differentiation (GO:0032330)2.13148624
164endocardial cushion development (GO:0003197)2.12736571
165regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.12208793
166positive regulation of endothelial cell apoptotic process (GO:2000353)2.11284339
167mesenchymal cell differentiation (GO:0048762)2.10880602
168regulation of hippo signaling (GO:0035330)2.09600396
169regulation of mononuclear cell migration (GO:0071675)2.09177519
170positive regulation of mesenchymal cell proliferation (GO:0002053)2.08805865
171regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.08567762

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1AR_21909140_ChIP-Seq_LNCAP_Human3.74669614
2E2F7_22180533_ChIP-Seq_HELA_Human3.63398650
3CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.78991133
4TP63_17297297_ChIP-ChIP_HaCaT_Human2.78446113
5TRIM28_21343339_ChIP-Seq_HEK293_Human2.70638293
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.49865494
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.38359921
8GBX2_23144817_ChIP-Seq_PC3_Human2.29421722
9ELK1_19687146_ChIP-ChIP_HELA_Human2.19932740
10SMAD_19615063_ChIP-ChIP_OVARY_Human2.16953446
11RBPJ_22232070_ChIP-Seq_NCS_Mouse2.10307409
12* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.09312263
13HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.08402542
14WT1_19549856_ChIP-ChIP_CCG9911_Human2.07332386
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.04698629
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.01474336
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.01431629
18* CJUN_26792858_Chip-Seq_BT549_Human2.00566922
19TP53_16413492_ChIP-PET_HCT116_Human1.99929407
20BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.98179585
21E2F4_17652178_ChIP-ChIP_JURKAT_Human1.95231117
22ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.95018077
23ZNF217_24962896_ChIP-Seq_MCF-7_Human1.93597061
24CDX2_19796622_ChIP-Seq_MESCs_Mouse1.88190386
25BRD4_25478319_ChIP-Seq_HGPS_Human1.85285209
26EP300_21415370_ChIP-Seq_HL-1_Mouse1.81127513
27EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.78777398
28FOXM1_23109430_ChIP-Seq_U2OS_Human1.75317384
29* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.73999638
30FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.68355507
31JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.66825404
32TP63_19390658_ChIP-ChIP_HaCaT_Human1.66025279
33JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.65822259
34CLOCK_20551151_ChIP-Seq_293T_Human1.63443032
35SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.61607736
36PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.58466534
37TP53_18474530_ChIP-ChIP_U2OS_Human1.55835453
38TCF4_18268006_ChIP-ChIP_LS174T_Human1.55706327
39FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.54943450
40SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.53672023
41FOXM1_26456572_ChIP-Seq_MCF-7_Human1.51389433
42KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.50234410
43NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.47003290
44* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46430665
45NRF2_20460467_ChIP-Seq_MEFs_Mouse1.43162750
46NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.43162750
47TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.42614697
48RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.42073815
49RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41570337
50AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.40642488
51ESR1_20079471_ChIP-ChIP_T-47D_Human1.40011400
52* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.39753400
53SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.37759701
54SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.37759701
55SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.37167818
56KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.36883495
57EED_16625203_ChIP-ChIP_MESCs_Mouse1.36415266
58KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.35667877
59SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.35650723
60ELK1_22589737_ChIP-Seq_MCF10A_Human1.31787276
61PIAS1_25552417_ChIP-Seq_VCAP_Human1.31363142
62EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.31274102
63MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.31018482
64ISL1_27105846_Chip-Seq_CPCs_Mouse1.30472478
65CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.29973555
66SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.29304275
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28988337
68* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.28586824
69SOX17_20123909_ChIP-Seq_XEN_Mouse1.28576474
70PPAR_26484153_Chip-Seq_NCI-H1993_Human1.27249378
71* SOX2_20726797_ChIP-Seq_SW620_Human1.26887064
72IGF1R_20145208_ChIP-Seq_DFB_Human1.26104094
73GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.25804800
74PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25376696
75SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24559250
76* ATF3_27146783_Chip-Seq_COLON_Human1.24371953
77UBF1/2_26484160_Chip-Seq_HMECs_Human1.23891294
78* TP63_23658742_ChIP-Seq_EP156T_Human1.22440136
79HIF1A_21447827_ChIP-Seq_MCF-7_Human1.21965612
80SOX9_24532713_ChIP-Seq_HFSC_Mouse1.19541768
81TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.19482516
82PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.19300078
83Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.18531837
84TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.18150078
85STAT6_21828071_ChIP-Seq_BEAS2B_Human1.17674637
86VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16621461
87NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.16076598
88NELFA_20434984_ChIP-Seq_ESCs_Mouse1.15799541
89ESR1_21235772_ChIP-Seq_MCF-7_Human1.15529187
90RNF2_18974828_ChIP-Seq_MESCs_Mouse1.15454013
91EZH2_18974828_ChIP-Seq_MESCs_Mouse1.15454013
92MYC_18555785_ChIP-Seq_MESCs_Mouse1.15200128
93AHR_22903824_ChIP-Seq_MCF-7_Human1.14342481
94TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.14206151
95AR_21572438_ChIP-Seq_LNCaP_Human1.14036872
96MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13670637
97STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.13511378
98FUS_26573619_Chip-Seq_HEK293_Human1.13276524
99SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.12928275
100* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.12886574
101CTNNB1_20460455_ChIP-Seq_HCT116_Human1.12555793
102POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12017567
103ARNT_22903824_ChIP-Seq_MCF-7_Human1.11758289
104RXR_22108803_ChIP-Seq_LS180_Human1.11241022
105STAT3_23295773_ChIP-Seq_U87_Human1.09827871
106PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.08988140
107CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.08377773
108* EWS_26573619_Chip-Seq_HEK293_Human1.08195677
109EZH2_27304074_Chip-Seq_ESCs_Mouse1.06244165
110TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.06155686
111* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05425687
112SMAD4_21799915_ChIP-Seq_A2780_Human1.04604657
113PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04565675
114YAP1_20516196_ChIP-Seq_MESCs_Mouse1.04486722
115DCP1A_22483619_ChIP-Seq_HELA_Human1.04314862
116* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04134965
117RNF2_27304074_Chip-Seq_ESCs_Mouse1.03774106
118DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.03602721
119PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03381082
120MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.03093490
121SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.02914204
122ZFP57_27257070_Chip-Seq_ESCs_Mouse1.02802636
123JARID2_20064375_ChIP-Seq_MESCs_Mouse1.02709249
124E2F1_21310950_ChIP-Seq_MCF-7_Human1.02244571
125VDR_24787735_ChIP-Seq_THP-1_Human1.01291249
126FOXO3_23340844_ChIP-Seq_DLD1_Human1.00544324
127GABP_17652178_ChIP-ChIP_JURKAT_Human1.00294578
128NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99015395
129SMAD3_21741376_ChIP-Seq_EPCs_Human0.99006042
130* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98912411
131POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97767945
132* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96496879
133RING1B_27294783_Chip-Seq_NPCs_Mouse0.96394684
134GATA2_21666600_ChIP-Seq_HMVEC_Human0.96054121
135FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95933509
136PCGF2_27294783_Chip-Seq_ESCs_Mouse0.95521454
137KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.95496671
138E2F1_18555785_Chip-Seq_ESCs_Mouse0.95120192
139SMAD3_21741376_ChIP-Seq_HESCs_Human0.94772415
140ZNF263_19887448_ChIP-Seq_K562_Human0.93654675
141* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.93512777
142GATA4_21415370_ChIP-Seq_HL-1_Mouse0.89022248
143P300_27058665_Chip-Seq_ZR-75-30cells_Human0.88879201
144HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.85795722
145PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.85783840
146RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.85207473
147ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.84410683
148FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.83262542
149ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.82944889
150CDX2_22108803_ChIP-Seq_LS180_Human0.81465689

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.03328360
2MP0005257_abnormal_intraocular_pressure3.81873984
3MP0005623_abnormal_meninges_morphology3.07660632
4MP0005503_abnormal_tendon_morphology2.92376771
5MP0000569_abnormal_digit_pigmentation2.83293865
6MP0005275_abnormal_skin_tensile2.71788331
7MP0003705_abnormal_hypodermis_morpholog2.60260164
8MP0009697_abnormal_copulation2.57179269
9MP0004272_abnormal_basement_membrane2.36791478
10MP0001299_abnormal_eye_distance/2.25216461
11MP0003279_aneurysm2.23485309
12MP0009780_abnormal_chondrocyte_physiolo2.12847756
13MP0010368_abnormal_lymphatic_system2.05891163
14MP0003385_abnormal_body_wall2.04748705
15MP0003941_abnormal_skin_development1.98943317
16MP0009250_abnormal_appendicular_skeleto1.97414037
17MP0010030_abnormal_orbit_morphology1.96846204
18MP0010352_gastrointestinal_tract_polyps1.92991094
19MP0010234_abnormal_vibrissa_follicle1.91852702
20MP0003566_abnormal_cell_adhesion1.86689199
21MP0000733_abnormal_muscle_development1.86168520
22MP0001958_emphysema1.84750572
23MP0003091_abnormal_cell_migration1.82193873
24MP0009384_cardiac_valve_regurgitation1.76070839
25MP0003937_abnormal_limbs/digits/tail_de1.74123727
26MP0003191_abnormal_cellular_cholesterol1.72301533
27MP0005171_absent_coat_pigmentation1.70632886
28MP0003045_fibrosis1.68210944
29MP0005508_abnormal_skeleton_morphology1.61775517
30MP0000537_abnormal_urethra_morphology1.60167726
31MP0004957_abnormal_blastocyst_morpholog1.52695368
32MP0003755_abnormal_palate_morphology1.51366970
33MP0000428_abnormal_craniofacial_morphol1.51072875
34MP0009053_abnormal_anal_canal1.47232263
35MP0008007_abnormal_cellular_replicative1.46186038
36MP0001879_abnormal_lymphatic_vessel1.45372365
37MP0005076_abnormal_cell_differentiation1.45333345
38MP0000432_abnormal_head_morphology1.41405968
39MP0000566_synostosis1.40352979
40MP0000534_abnormal_ureter_morphology1.37136411
41MP0003121_genomic_imprinting1.35888798
42MP0002697_abnormal_eye_size1.35807021
43MP0000767_abnormal_smooth_muscle1.34197270
44MP0001346_abnormal_lacrimal_gland1.32089133
45MP0002896_abnormal_bone_mineralization1.31081232
46MP0010094_abnormal_chromosome_stability1.29837520
47MP0003935_abnormal_craniofacial_develop1.28916813
48MP0000049_abnormal_middle_ear1.28527416
49MP0005367_renal/urinary_system_phenotyp1.28353527
50MP0000516_abnormal_urinary_system1.28353527
51MP0008932_abnormal_embryonic_tissue1.28254146
52MP0001849_ear_inflammation1.27913250
53MP0001348_abnormal_lacrimal_gland1.25977152
54MP0003942_abnormal_urinary_system1.25404337
55MP0002282_abnormal_trachea_morphology1.24886948
56MP0000749_muscle_degeneration1.24589979
57MP0002116_abnormal_craniofacial_bone1.23098499
58MP0003122_maternal_imprinting1.21251284
59MP0005197_abnormal_uvea_morphology1.21187683
60MP0002234_abnormal_pharynx_morphology1.20557499
61MP0003111_abnormal_nucleus_morphology1.17519834
62MP0003115_abnormal_respiratory_system1.16369681
63MP0002233_abnormal_nose_morphology1.15178925
64MP0000647_abnormal_sebaceous_gland1.15061631
65MP0002113_abnormal_skeleton_development1.14990882
66MP0005248_abnormal_Harderian_gland1.14518435
67MP0000163_abnormal_cartilage_morphology1.12529526
68MP0002109_abnormal_limb_morphology1.12226667
69MP0002115_abnormal_skeleton_extremities1.12067898
70MP0002932_abnormal_joint_morphology1.12014835
71MP0000579_abnormal_nail_morphology1.10547313
72MP0003950_abnormal_plasma_membrane1.09318147
73MP0003077_abnormal_cell_cycle1.09073459
74MP0003453_abnormal_keratinocyte_physiol1.09018386
75MP0000627_abnormal_mammary_gland1.08050853
76MP0005023_abnormal_wound_healing1.07825347
77MP0010307_abnormal_tumor_latency1.06706560
78MP0000427_abnormal_hair_cycle1.05856172
79MP0002060_abnormal_skin_morphology1.05043727
80MP0005164_abnormal_response_to1.04662554
81MP0004134_abnormal_chest_morphology1.04203326
82MP0002249_abnormal_larynx_morphology1.04180293
83MP0002877_abnormal_melanocyte_morpholog1.04004636
84MP0002108_abnormal_muscle_morphology1.03864768
85MP0002998_abnormal_bone_remodeling0.99458410
86MP0001216_abnormal_epidermal_layer0.99124108
87MP0002925_abnormal_cardiovascular_devel0.98564536
88MP0003693_abnormal_embryo_hatching0.97177052
89MP0004084_abnormal_cardiac_muscle0.97047992
90MP0003567_abnormal_fetal_cardiomyocyte0.96716337
91MP0004197_abnormal_fetal_growth/weight/0.95412564
92MP0002102_abnormal_ear_morphology0.95393865
93MP0003943_abnormal_hepatobiliary_system0.94441722
94MP0003828_pulmonary_edema0.93582382
95MP0000383_abnormal_hair_follicle0.93419112
96MP0006054_spinal_hemorrhage0.93261130
97MP0002277_abnormal_respiratory_mucosa0.92645423
98MP0000467_abnormal_esophagus_morphology0.92144224
99MP0002168_other_aberrant_phenotype0.91977210
100MP0002177_abnormal_outer_ear0.91028877
101MP0000013_abnormal_adipose_tissue0.90965184
102MP0005165_increased_susceptibility_to0.90876696
103MP0000350_abnormal_cell_proliferation0.90872767
104MP0002086_abnormal_extraembryonic_tissu0.90537984
105MP0001293_anophthalmia0.90217305
106MP0001697_abnormal_embryo_size0.89474566
107MP0004233_abnormal_muscle_weight0.89213131
108MP0002085_abnormal_embryonic_tissue0.88511516
109MP0002111_abnormal_tail_morphology0.88451007
110MP0003787_abnormal_imprinting0.87692310
111MP0004185_abnormal_adipocyte_glucose0.87654751
112MP0005390_skeleton_phenotype0.87574793
113MP0002092_abnormal_eye_morphology0.86340200
114MP0000751_myopathy0.85810529
115MP0005408_hypopigmentation0.84214810
116MP0001672_abnormal_embryogenesis/_devel0.83377475
117MP0005380_embryogenesis_phenotype0.83377475
118MP0000750_abnormal_muscle_regeneration0.82694278
119MP0002084_abnormal_developmental_patter0.82567133
120MP0001286_abnormal_eye_development0.81751409
121MP0003984_embryonic_growth_retardation0.81422290
122MP0003283_abnormal_digestive_organ0.81133911
123MP0002114_abnormal_axial_skeleton0.80456907
124MP0001915_intracranial_hemorrhage0.80211479
125MP0001614_abnormal_blood_vessel0.79804376
126MP0003252_abnormal_bile_duct0.79647752
127MP0002938_white_spotting0.79625589
128MP0001730_embryonic_growth_arrest0.79445329
129MP0000762_abnormal_tongue_morphology0.78704780
130MP0006138_congestive_heart_failure0.77764980
131MP0001175_abnormal_lung_morphology0.77484041
132MP0003123_paternal_imprinting0.77252246
133MP0002269_muscular_atrophy0.77130799
134MP0002332_abnormal_exercise_endurance0.76761803
135MP0001243_abnormal_dermal_layer0.76630714
136MP0002088_abnormal_embryonic_growth/wei0.76280684
137MP0005409_darkened_coat_color0.76153110
138MP0005621_abnormal_cell_physiology0.76139331
139MP0010678_abnormal_skin_adnexa0.76120074
140MP0003890_abnormal_embryonic-extraembry0.75649548
141MP0002295_abnormal_pulmonary_circulatio0.74146388
142MP0002128_abnormal_blood_circulation0.72827135
143MP0004858_abnormal_nervous_system0.72614032
144MP0009278_abnormal_bone_marrow0.69643720
145MP0005193_abnormal_anterior_eye0.69184230

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.69917951
2Protrusio acetabuli (HP:0003179)3.88061500
3Aortic dissection (HP:0002647)3.37222406
4Shallow orbits (HP:0000586)3.32659661
5Aortic aneurysm (HP:0004942)3.17368081
6Onycholysis (HP:0001806)3.10629285
7Cerebral aneurysm (HP:0004944)3.06449624
8Ankle contracture (HP:0006466)2.94938228
9Genu recurvatum (HP:0002816)2.93378840
10Ankyloglossia (HP:0010296)2.92115219
11Vascular tortuosity (HP:0004948)2.82243065
12Atrophic scars (HP:0001075)2.81810752
13Soft skin (HP:0000977)2.81584067
14Milia (HP:0001056)2.81139725
15Reduced subcutaneous adipose tissue (HP:0003758)2.80862235
16Absent frontal sinuses (HP:0002688)2.76518097
17Arterial tortuosity (HP:0005116)2.69602975
18Abnormality of oral frenula (HP:0000190)2.69478332
19Bladder diverticulum (HP:0000015)2.60385110
20Cervical subluxation (HP:0003308)2.58680791
21Mesomelia (HP:0003027)2.57191684
22Abnormality of the nasal septum (HP:0000419)2.50797007
23Dilatation of the ascending aorta (HP:0005111)2.47977332
24Entropion (HP:0000621)2.45504070
25Mitral valve prolapse (HP:0001634)2.44372505
26Pterygium (HP:0001059)2.42450482
27Vertebral arch anomaly (HP:0008438)2.38558011
28Vertebral compression fractures (HP:0002953)2.36747853
29Selective tooth agenesis (HP:0001592)2.34759487
30Neonatal short-limb short stature (HP:0008921)2.30183845
31Wrist flexion contracture (HP:0001239)2.29679482
32Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.29464342
33Short 4th metacarpal (HP:0010044)2.29464342
34Ulnar bowing (HP:0003031)2.29395368
35Mitral stenosis (HP:0001718)2.28049713
36Cardiovascular calcification (HP:0011915)2.27433775
37Fragile nails (HP:0001808)2.26291260
38Conjugated hyperbilirubinemia (HP:0002908)2.25001954
39Abnormality of the umbilical cord (HP:0010881)2.21976318
40Microglossia (HP:0000171)2.19724539
41Scapular winging (HP:0003691)2.19287810
42Abnormality of the frontal sinuses (HP:0002687)2.18040840
43Glucose intolerance (HP:0000833)2.17482006
44Natal tooth (HP:0000695)2.15597627
45Coronal craniosynostosis (HP:0004440)2.14877048
46Spinal cord lesions (HP:0100561)2.09891515
47Syringomyelia (HP:0003396)2.09891515
48Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.09725804
49Abnormality of dentin (HP:0010299)2.08951302
50Fragile skin (HP:0001030)2.08123959
51Wormian bones (HP:0002645)2.06962315
52Tibial bowing (HP:0002982)2.05698638
53Fibular aplasia (HP:0002990)2.05220815
54Abnormalities of placenta or umbilical cord (HP:0001194)2.04764263
55Broad metatarsal (HP:0001783)2.03858997
56Termporal pattern (HP:0011008)2.01876227
57Insidious onset (HP:0003587)2.01876227
58Missing ribs (HP:0000921)2.01198800
59Overgrowth (HP:0001548)2.00144673
60Amniotic constriction ring (HP:0009775)1.98982737
61Abnormality of placental membranes (HP:0011409)1.98982737
62Bowel diverticulosis (HP:0005222)1.98149850
63Hypoplastic ischia (HP:0003175)1.98075522
64Follicular hyperkeratosis (HP:0007502)1.96758774
65Blue sclerae (HP:0000592)1.96368082
66Abnormal auditory evoked potentials (HP:0006958)1.96130819
67Chorioretinal atrophy (HP:0000533)1.95912359
68Upper limb muscle weakness (HP:0003484)1.95080398
69Insomnia (HP:0100785)1.94533869
70Subacute progressive viral hepatitis (HP:0006572)1.93909575
71Abnormality of the fetal cardiovascular system (HP:0010948)1.93560319
72Abnormal umbilical cord blood vessels (HP:0011403)1.93560319
73Single umbilical artery (HP:0001195)1.93560319
74Delayed gross motor development (HP:0002194)1.93401998
75Abnormality of the distal phalanges of the toes (HP:0010182)1.93253338
76Pulmonic stenosis (HP:0001642)1.91521847
77Sensory axonal neuropathy (HP:0003390)1.91465304
78Limited elbow extension (HP:0001377)1.90406132
79Osteolytic defects of the hand bones (HP:0009699)1.90040710
80Osteolytic defects of the phalanges of the hand (HP:0009771)1.90040710
81Joint laxity (HP:0001388)1.89634072
82Abnormality of carpal bone ossification (HP:0006257)1.88477811
83Broad thumb (HP:0011304)1.87753108
84Posterior subcapsular cataract (HP:0007787)1.87560226
85Tetraparesis (HP:0002273)1.87380795
86Bell-shaped thorax (HP:0001591)1.84960180
87Broad long bones (HP:0005622)1.84541072
88Spondylolisthesis (HP:0003302)1.84087370
89Limited hip movement (HP:0008800)1.83385033
90Vascular calcification (HP:0004934)1.83169988
91Poikiloderma (HP:0001029)1.82600302
92Elbow flexion contracture (HP:0002987)1.82231828
93Persistence of primary teeth (HP:0006335)1.81110837
94Spinal rigidity (HP:0003306)1.80742480
95Spinal cord compression (HP:0002176)1.80534960
96Lower limb amyotrophy (HP:0007210)1.80016542
97Aneurysm (HP:0002617)1.79928206
98Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.79000999
99Nail dystrophy (HP:0008404)1.78753832
100Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.78571815
101Peritonitis (HP:0002586)1.78283021
102Knee flexion contracture (HP:0006380)1.77870662
103Abnormality of the distal phalanx of the thumb (HP:0009617)1.77114083
104Abnormality of proline metabolism (HP:0010907)1.76804130
105Hydroxyprolinuria (HP:0003080)1.76804130
106Thick nail (HP:0001805)1.76371455
107Radial bowing (HP:0002986)1.75717819
108Right ventricular cardiomyopathy (HP:0011663)1.74821163
109Rectal prolapse (HP:0002035)1.74589091
110Decreased skull ossification (HP:0004331)1.74502553
111Asymmetry of the thorax (HP:0001555)1.72932554
112Stillbirth (HP:0003826)1.72362124
113Ectopic kidney (HP:0000086)1.71801321
114Deviation of the hallux (HP:0010051)1.71540825
115Broad phalanx (HP:0006009)1.71315291
116Epiphyseal dysplasia (HP:0002656)1.69254540
117Adrenal hypoplasia (HP:0000835)1.69221013
118Plantar hyperkeratosis (HP:0007556)1.68084122
119Delayed closure of the anterior fontanelle (HP:0001476)1.67876376
120Aortic regurgitation (HP:0001659)1.67589429
121Chromsome breakage (HP:0040012)1.66419304
122Hallux valgus (HP:0001822)1.65456661
123Abnormality of the ischium (HP:0003174)1.65397296
124Broad ribs (HP:0000885)1.65291376
125Hip contracture (HP:0003273)1.64263119
126Bowed forearm bones (HP:0003956)1.64080921
127Bowing of the arm (HP:0006488)1.64080921
128Abnormality of the 4th metacarpal (HP:0010012)1.63620957
129Abnormal ossification of hand bones (HP:0005921)1.63579001
130Narrow palate (HP:0000189)1.63352183
131Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.63062989
132Vertebral hypoplasia (HP:0008417)1.63010287
133Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.63010287
134Mildly elevated creatine phosphokinase (HP:0008180)1.62939242
135Ridged nail (HP:0001807)1.62541122
136Abnormality of the intrinsic pathway (HP:0010989)1.62083360
137Broad phalanges of the hand (HP:0009768)1.60991147
138Abnormality of incisor morphology (HP:0011063)1.60303704
139Nuclear cataract (HP:0100018)1.59608491
140Bilateral sensorineural hearing impairment (HP:0008619)1.59470285
141Increased number of teeth (HP:0011069)1.59389709
142Wide anterior fontanel (HP:0000260)1.59357026
143Short nail (HP:0001799)1.58981216
144Aplasia/Hypoplasia of the scapulae (HP:0006713)1.58307850
145Hypoplastic scapulae (HP:0000882)1.58307850
146Broad finger (HP:0001500)1.58168965
147Renal duplication (HP:0000075)1.57999449
148Distal lower limb amyotrophy (HP:0008944)1.55971341
149Exostoses (HP:0100777)1.55427923
150Increased connective tissue (HP:0009025)1.55031631
151Fused cervical vertebrae (HP:0002949)1.54881552
152Flat cornea (HP:0007720)1.53645743
153Chromosomal breakage induced by crosslinking agents (HP:0003221)1.53549421
154Hypoplasia of the iris (HP:0007676)1.52680942
155Craniofacial hyperostosis (HP:0004493)1.51666991
156Abnormality of the acetabulum (HP:0003170)1.51168024
157Dislocated radial head (HP:0003083)1.51103405
158Myelomeningocele (HP:0002475)1.50984881
159Type 1 muscle fiber predominance (HP:0003803)1.50972512
160Abnormality of the right ventricle (HP:0001707)1.50649501
161Mitral regurgitation (HP:0001653)1.50194359
162Deviation of the thumb (HP:0009603)1.50051199
163Abnormality of the peritoneum (HP:0002585)1.49975836

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.54512184
2CDK123.75730861
3DDR23.63496496
4TTN3.62413836
5TRIM283.16456689
6MST42.72681221
7PDGFRA2.53043914
8STK32.44194447
9EIF2AK32.41911271
10EIF2AK12.29457794
11EPHB22.16858916
12SIK12.14658336
13LATS22.10490870
14CAMK1D1.99814690
15STK38L1.98204434
16TGFBR21.97763694
17DMPK1.96171392
18EPHA21.81726778
19LIMK11.69604269
20TRPM71.69291767
21NEK11.68250630
22BUB11.66433037
23SIK31.62260140
24ZAK1.57610658
25PBK1.57492655
26CDK81.52615353
27NUAK11.46995809
28BMX1.45808061
29PLK21.45496624
30MAP3K121.44528614
31PTK21.43087135
32ERBB31.41620796
33SCYL21.40060799
34LMTK21.38818583
35CAMK1G1.38358253
36PDGFRB1.38129528
37KSR11.37898135
38PAK21.37800395
39RIPK11.37035935
40MET1.33534487
41BRSK21.31985451
42MYLK1.31021696
43MTOR1.23923138
44FER1.21868108
45BRD41.20663763
46TSSK61.15256111
47ERBB41.14510418
48NEK91.07378163
49EIF2AK21.06319079
50CDK61.06106112
51FRK1.05293114
52MKNK11.05137864
53NTRK11.05058924
54PKN21.02176728
55CDC71.02067637
56SRPK10.97695443
57PAK40.96691609
58WEE10.96630466
59FGFR10.96195225
60ROCK10.95632334
61RPS6KA40.92005817
62TESK10.91957896
63BRSK10.90271180
64WNK10.88479801
65MARK30.88401423
66STK390.86092125
67CDK70.82475643
68FGFR20.81883006
69PIK3CA0.81880349
70TNIK0.81583039
71MELK0.81249684
72PAK30.81225013
73NME20.80248592
74FLT30.77085829
75IRAK30.76853497
76CHEK20.75928439
77AKT20.74244995
78BCR0.74225709
79MOS0.73962899
80SIK20.72292654
81TTK0.71620022
82CHUK0.71526582
83PLK10.69992520
84PLK30.68396856
85ALK0.68029975
86PTK60.67578780
87TRIB30.66132640
88INSR0.65563409
89STK100.65434161
90MKNK20.64733314
91PNCK0.62935326
92CDC42BPA0.61980176
93TYRO30.60644716
94BMPR1B0.59887754
95YES10.58797612
96PLK40.58237552
97PRKCI0.58139911
98ICK0.57580380
99MAP3K90.57272525
100ABL20.57179668
101INSRR0.55790552
102ATR0.55210689
103JAK10.55118088
104NEK20.55016955
105ATM0.53938012
106FGR0.53589175
107ERBB20.53193421
108WNK40.49810007
109RET0.49092105
110PRKD30.48552584
111STK40.48536243
112MAP3K80.48363859
113STK240.47792019
114EPHA30.46517471
115AKT10.46137749
116FGFR30.44711235
117ADRBK10.43445847
118BMPR20.41988155
119SRC0.41715200
120TGFBR10.41623251
121MAPK140.41195827
122STK380.41163241
123IGF1R0.41113451
124CSNK1D0.41101155
125ROCK20.38859935
126MAPK10.38487788
127CDK90.38474879
128CHEK10.38405652
129CDK10.38133969
130MAP3K140.37363030
131PRKCE0.37082040
132EEF2K0.36930354
133AURKB0.36461413
134ARAF0.36436545
135CSNK1A1L0.35504275
136ILK0.35394942
137MINK10.35380607
138MST1R0.35292431
139CLK10.34783006
140PAK60.34543834
141ABL10.33775084
142MAPK100.33453037
143AKT30.32866046
144EGFR0.30962413
145PTK2B0.30684328
146CCNB10.28863166
147BRAF0.27860539
148GSK3A0.27397378
149PAK10.25293887
150MAP3K30.23290598
151CAMK2D0.21331392

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.17988242
2ECM-receptor interaction_Homo sapiens_hsa045122.43653342
3Vitamin B6 metabolism_Homo sapiens_hsa007502.33302224
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.18211140
5Non-homologous end-joining_Homo sapiens_hsa034502.07627943
6Adherens junction_Homo sapiens_hsa045202.05596250
7Focal adhesion_Homo sapiens_hsa045101.97914014
8Protein export_Homo sapiens_hsa030601.90624124
9Small cell lung cancer_Homo sapiens_hsa052221.89403491
10Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.86230280
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.81495863
12MicroRNAs in cancer_Homo sapiens_hsa052061.81481546
13Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.75434052
14Proteoglycans in cancer_Homo sapiens_hsa052051.74334397
15Hippo signaling pathway_Homo sapiens_hsa043901.72100958
16TGF-beta signaling pathway_Homo sapiens_hsa043501.68928968
17Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.58857449
18Nucleotide excision repair_Homo sapiens_hsa034201.56620090
19Basal cell carcinoma_Homo sapiens_hsa052171.55394714
20Thyroid cancer_Homo sapiens_hsa052161.53565908
21Chronic myeloid leukemia_Homo sapiens_hsa052201.53202276
22Dilated cardiomyopathy_Homo sapiens_hsa054141.49772483
23Melanoma_Homo sapiens_hsa052181.45768323
24AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.44324963
25Amoebiasis_Homo sapiens_hsa051461.43953659
26Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.39370763
27Axon guidance_Homo sapiens_hsa043601.37737079
28Pancreatic cancer_Homo sapiens_hsa052121.32898242
29Viral myocarditis_Homo sapiens_hsa054161.29387544
30Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.28011522
31Basal transcription factors_Homo sapiens_hsa030221.27595559
32Regulation of actin cytoskeleton_Homo sapiens_hsa048101.27061615
33Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.22610683
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.22136983
35Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.21736206
36N-Glycan biosynthesis_Homo sapiens_hsa005101.20456363
37Prostate cancer_Homo sapiens_hsa052151.19828849
38RNA transport_Homo sapiens_hsa030131.19090843
39Colorectal cancer_Homo sapiens_hsa052101.17674146
40TNF signaling pathway_Homo sapiens_hsa046681.16243977
41PI3K-Akt signaling pathway_Homo sapiens_hsa041511.13923154
42Malaria_Homo sapiens_hsa051441.13856033
43Hedgehog signaling pathway_Homo sapiens_hsa043401.13008586
44Glioma_Homo sapiens_hsa052141.09746789
45Pyrimidine metabolism_Homo sapiens_hsa002401.08068044
46Tight junction_Homo sapiens_hsa045301.08037664
47Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.05787563
48Steroid biosynthesis_Homo sapiens_hsa001001.05165248
49p53 signaling pathway_Homo sapiens_hsa041151.04911455
50Wnt signaling pathway_Homo sapiens_hsa043101.04483347
51Endometrial cancer_Homo sapiens_hsa052131.02730131
52Pathways in cancer_Homo sapiens_hsa052001.01992245
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.01741599
54mTOR signaling pathway_Homo sapiens_hsa041501.00994114
55Fanconi anemia pathway_Homo sapiens_hsa034600.99978467
56Leukocyte transendothelial migration_Homo sapiens_hsa046700.99791216
57Rap1 signaling pathway_Homo sapiens_hsa040150.99693159
58HTLV-I infection_Homo sapiens_hsa051660.99214348
59Mismatch repair_Homo sapiens_hsa034300.97770298
60Sulfur metabolism_Homo sapiens_hsa009200.97489625
61Renal cell carcinoma_Homo sapiens_hsa052110.96673945
62Ovarian steroidogenesis_Homo sapiens_hsa049130.96559044
63Toxoplasmosis_Homo sapiens_hsa051450.95575600
64Bladder cancer_Homo sapiens_hsa052190.95546699
65DNA replication_Homo sapiens_hsa030300.95048589
66Protein digestion and absorption_Homo sapiens_hsa049740.93836811
67Osteoclast differentiation_Homo sapiens_hsa043800.92173412
68Toll-like receptor signaling pathway_Homo sapiens_hsa046200.91310840
69Sphingolipid metabolism_Homo sapiens_hsa006000.90327216
70Cell cycle_Homo sapiens_hsa041100.89637945
71Viral carcinogenesis_Homo sapiens_hsa052030.88825494
72Hepatitis B_Homo sapiens_hsa051610.88263319
73NF-kappa B signaling pathway_Homo sapiens_hsa040640.87230242
74Transcriptional misregulation in cancer_Homo sapiens_hsa052020.87098622
75ErbB signaling pathway_Homo sapiens_hsa040120.85414281
76Notch signaling pathway_Homo sapiens_hsa043300.83823733
77Platelet activation_Homo sapiens_hsa046110.83785894
78Dorso-ventral axis formation_Homo sapiens_hsa043200.82350548
79FoxO signaling pathway_Homo sapiens_hsa040680.82089887
80Phagosome_Homo sapiens_hsa041450.81201238
81Prolactin signaling pathway_Homo sapiens_hsa049170.79403831
82Salmonella infection_Homo sapiens_hsa051320.79074015
83Ras signaling pathway_Homo sapiens_hsa040140.78665468
84Oocyte meiosis_Homo sapiens_hsa041140.78506180
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.78441676
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.77159698
87Leishmaniasis_Homo sapiens_hsa051400.77123598
88Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75948902
89Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.74424449
90Apoptosis_Homo sapiens_hsa042100.74171297
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72855035
92Type II diabetes mellitus_Homo sapiens_hsa049300.72413462
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72110540
94Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71635866
95HIF-1 signaling pathway_Homo sapiens_hsa040660.71136096
96Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.70863031
97Rheumatoid arthritis_Homo sapiens_hsa053230.70027215
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.69232406
99MAPK signaling pathway_Homo sapiens_hsa040100.68872493
100Longevity regulating pathway - mammal_Homo sapiens_hsa042110.68065532
101Non-small cell lung cancer_Homo sapiens_hsa052230.65828283
102RNA polymerase_Homo sapiens_hsa030200.65644265
103Shigellosis_Homo sapiens_hsa051310.65622810
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.65345359
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65118539
106Melanogenesis_Homo sapiens_hsa049160.63604133
107Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.63442615
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63275959
109GnRH signaling pathway_Homo sapiens_hsa049120.63216160
110Circadian rhythm_Homo sapiens_hsa047100.63096979
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62854877
112Selenocompound metabolism_Homo sapiens_hsa004500.61764238
113Homologous recombination_Homo sapiens_hsa034400.61373413
114Phospholipase D signaling pathway_Homo sapiens_hsa040720.60367921
115Tuberculosis_Homo sapiens_hsa051520.60282860
116Herpes simplex infection_Homo sapiens_hsa051680.59309963
117Gap junction_Homo sapiens_hsa045400.58080030
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.57600204
119Estrogen signaling pathway_Homo sapiens_hsa049150.57597813
120Glycosaminoglycan degradation_Homo sapiens_hsa005310.56879070
121One carbon pool by folate_Homo sapiens_hsa006700.56809288
122Autoimmune thyroid disease_Homo sapiens_hsa053200.56628816
123Pentose phosphate pathway_Homo sapiens_hsa000300.56467411
124Measles_Homo sapiens_hsa051620.56147103
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.55636960
126cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55218732
127Influenza A_Homo sapiens_hsa051640.53562393
128Choline metabolism in cancer_Homo sapiens_hsa052310.53322030
129Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.53036612
130Oxytocin signaling pathway_Homo sapiens_hsa049210.51886667
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51880102
132Systemic lupus erythematosus_Homo sapiens_hsa053220.51355201
133Galactose metabolism_Homo sapiens_hsa000520.48566014
134RNA degradation_Homo sapiens_hsa030180.41753649
135Fatty acid biosynthesis_Homo sapiens_hsa000610.41734874
136mRNA surveillance pathway_Homo sapiens_hsa030150.41658588
137Glutathione metabolism_Homo sapiens_hsa004800.40114350
138Lysine degradation_Homo sapiens_hsa003100.39994616
139Pyruvate metabolism_Homo sapiens_hsa006200.39994417
140Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.39045372
141Endocytosis_Homo sapiens_hsa041440.38940136
142Biosynthesis of amino acids_Homo sapiens_hsa012300.38850061
143Folate biosynthesis_Homo sapiens_hsa007900.36779670
144Vibrio cholerae infection_Homo sapiens_hsa051100.32949145
1452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.30590628
146Purine metabolism_Homo sapiens_hsa002300.30570040
147Inositol phosphate metabolism_Homo sapiens_hsa005620.28208803
148Fructose and mannose metabolism_Homo sapiens_hsa000510.25365250

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