DCC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.90404845
2axonal fasciculation (GO:0007413)5.65201777
3neuron cell-cell adhesion (GO:0007158)5.34369590
4neuron recognition (GO:0008038)5.00694137
5response to pheromone (GO:0019236)4.81328124
6* central nervous system projection neuron axonogenesis (GO:0021952)4.75762611
7establishment of mitochondrion localization (GO:0051654)4.71742296
8dendritic spine morphogenesis (GO:0060997)4.68908351
9regulation of short-term neuronal synaptic plasticity (GO:0048172)4.60350827
10olfactory bulb development (GO:0021772)4.53593237
11nucleobase catabolic process (GO:0046113)4.49458773
12vocalization behavior (GO:0071625)4.48916294
13retinal ganglion cell axon guidance (GO:0031290)4.47234414
14cell migration in hindbrain (GO:0021535)4.39248102
15regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.35648770
16positive regulation of synapse maturation (GO:0090129)4.33665379
17dendrite morphogenesis (GO:0048813)4.26321495
18protein localization to synapse (GO:0035418)4.24541085
19regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.13215572
20mitochondrion transport along microtubule (GO:0047497)4.11405975
21establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.11405975
22positive regulation of mitochondrial fission (GO:0090141)4.07760049
23positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.03901083
24layer formation in cerebral cortex (GO:0021819)3.94573829
25regulation of synapse structural plasticity (GO:0051823)3.93123125
26neural tube formation (GO:0001841)3.87552579
27cerebral cortex radially oriented cell migration (GO:0021799)3.84306119
28neurotransmitter-gated ion channel clustering (GO:0072578)3.80184204
29limb bud formation (GO:0060174)3.79688914
30regulation of glutamate receptor signaling pathway (GO:1900449)3.70519373
31epithelial cilium movement (GO:0003351)3.69863599
32regulation of synapse maturation (GO:0090128)3.69152780
33calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.67501538
34epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.63678227
35positive regulation of synapse assembly (GO:0051965)3.63127412
36lateral sprouting from an epithelium (GO:0060601)3.62625021
37transmission of nerve impulse (GO:0019226)3.62022076
38cerebellum development (GO:0021549)3.59286112
39heparin metabolic process (GO:0030202)3.56176052
40heparin biosynthetic process (GO:0030210)3.56176052
41spinal cord development (GO:0021510)3.55378172
42* central nervous system neuron axonogenesis (GO:0021955)3.53535820
43mating behavior (GO:0007617)3.52165281
44synaptic vesicle exocytosis (GO:0016079)3.50543565
45ionotropic glutamate receptor signaling pathway (GO:0035235)3.49719661
46hippocampus development (GO:0021766)3.46423726
47G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.46225320
48glutamate receptor signaling pathway (GO:0007215)3.44888703
49positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.43623505
50mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.43623505
51cerebellar Purkinje cell differentiation (GO:0021702)3.41388680
52auditory behavior (GO:0031223)3.40224759
53neuronal ion channel clustering (GO:0045161)3.39270357
54neuron projection extension involved in neuron projection guidance (GO:1902284)3.39227506
55axon extension involved in axon guidance (GO:0048846)3.39227506
56presynaptic membrane organization (GO:0097090)3.38428098
57negative regulation of oligodendrocyte differentiation (GO:0048715)3.37533135
58regulation of synaptic vesicle exocytosis (GO:2000300)3.35165030
59positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.34209358
60prepulse inhibition (GO:0060134)3.32243095
61ganglion development (GO:0061548)3.31222892
62cerebellar granule cell differentiation (GO:0021707)3.30899629
63regulation of axon guidance (GO:1902667)3.30783040
64negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.30089171
65postsynaptic membrane organization (GO:0001941)3.29910574
66regulation of long-term neuronal synaptic plasticity (GO:0048169)3.28780778
67synaptic transmission, cholinergic (GO:0007271)3.28480490
68nonmotile primary cilium assembly (GO:0035058)3.28109161
69synaptic transmission, glutamatergic (GO:0035249)3.24854468
70regulation of neuronal synaptic plasticity (GO:0048168)3.21485429
71positive regulation of gastrulation (GO:2000543)3.20894677
72presynaptic membrane assembly (GO:0097105)3.20718812
73negative regulation of axon extension involved in axon guidance (GO:0048843)3.19940430
74regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.19014991
75adult walking behavior (GO:0007628)3.13956295
76neuron-neuron synaptic transmission (GO:0007270)3.13197040
77neurofilament cytoskeleton organization (GO:0060052)3.13021329
78response to auditory stimulus (GO:0010996)3.11298069
79* neuron migration (GO:0001764)3.11056031
80locomotory exploration behavior (GO:0035641)3.10886739
81intraciliary transport (GO:0042073)3.10259840
82regulation of NFAT protein import into nucleus (GO:0051532)3.07814452
83behavioral response to nicotine (GO:0035095)3.06615254
84regulation of synapse assembly (GO:0051963)3.04250233
85gonadal mesoderm development (GO:0007506)3.04199738
86neuromuscular synaptic transmission (GO:0007274)3.04134186
87cilium movement (GO:0003341)3.03517526
88positive regulation of dendritic spine morphogenesis (GO:0061003)3.03375090
89negative regulation of axon guidance (GO:1902668)3.03075120
90startle response (GO:0001964)3.03045203
91exploration behavior (GO:0035640)3.03019740
92synaptic vesicle maturation (GO:0016188)3.01661600
93protein localization to cilium (GO:0061512)3.00040155
94substrate-independent telencephalic tangential migration (GO:0021826)2.99398293
95substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.99398293
96cranial nerve morphogenesis (GO:0021602)2.98462576
97membrane hyperpolarization (GO:0060081)2.98179973
98regulation of synapse organization (GO:0050807)2.97858982
99organelle transport along microtubule (GO:0072384)2.93882539
100glutamate secretion (GO:0014047)2.93003320
101innervation (GO:0060384)2.92269940
102negative regulation of axon extension (GO:0030517)2.91432536
103behavioral defense response (GO:0002209)2.90959242
104behavioral fear response (GO:0001662)2.90959242
105protein polyglutamylation (GO:0018095)2.90412203
106sequestering of actin monomers (GO:0042989)2.89808334
107regulation of feeding behavior (GO:0060259)2.88867936
108homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.88431212
109head development (GO:0060322)2.88419729
110spinal cord association neuron differentiation (GO:0021527)2.87291064
111regulation of synaptic transmission, glutamatergic (GO:0051966)2.86648209
112* axonogenesis (GO:0007409)2.85438434
113dendritic spine organization (GO:0097061)2.85418815
114negative regulation of microtubule polymerization (GO:0031115)2.85062248
115regulation of synaptic vesicle transport (GO:1902803)2.82540603
116dendrite development (GO:0016358)2.82432959
117cytoskeleton-dependent intracellular transport (GO:0030705)2.81555552
118forebrain neuron differentiation (GO:0021879)2.80727706
119synaptic vesicle docking involved in exocytosis (GO:0016081)2.80470946
120regulation of excitatory postsynaptic membrane potential (GO:0060079)2.79529411
121synaptic vesicle endocytosis (GO:0048488)2.78761664
122cell differentiation in hindbrain (GO:0021533)2.77738444
123cerebral cortex cell migration (GO:0021795)2.76937596
124negative regulation of catenin import into nucleus (GO:0035414)2.76742952
125axon extension (GO:0048675)2.75710720
126striatum development (GO:0021756)2.75202922
127synapse assembly (GO:0007416)2.74686956
128heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.73595353
129mechanosensory behavior (GO:0007638)2.73201780
130positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.72848148
131synapse organization (GO:0050808)2.71902462
132regulation of postsynaptic membrane potential (GO:0060078)2.71797639
133regulation of mitochondrial fission (GO:0090140)2.71397512
134hindbrain development (GO:0030902)2.69538049
135regulation of dendritic spine morphogenesis (GO:0061001)2.68928424
136cornea development in camera-type eye (GO:0061303)2.68271792
137regulation of neurotransmitter secretion (GO:0046928)2.68204048
138regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.67237743
139establishment of nucleus localization (GO:0040023)2.66732635
140neuron fate determination (GO:0048664)2.64087818
141regulation of axon extension involved in axon guidance (GO:0048841)2.64059511
142behavioral response to ethanol (GO:0048149)2.62604096
143retinal cone cell development (GO:0046549)2.62346274
144* negative regulation of axonogenesis (GO:0050771)2.62222807

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.42410584
2GBX2_23144817_ChIP-Seq_PC3_Human3.68065047
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.26595628
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02667174
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.89529624
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.87160545
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.72114191
8* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.68348046
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.63062636
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.63062636
11* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.61859811
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.60372518
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.57787013
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.39663038
15CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.36708275
16RNF2_27304074_Chip-Seq_ESCs_Mouse2.34912254
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.34662258
18TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.33635095
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.33027574
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.30902555
21CBX2_27304074_Chip-Seq_ESCs_Mouse2.26904805
22REST_21632747_ChIP-Seq_MESCs_Mouse2.20972909
23MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12829810
24* PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.08097551
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.07642425
26RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.07377307
27* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.06047025
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.02047005
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96526654
30BMI1_23680149_ChIP-Seq_NPCS_Mouse1.93112108
31DROSHA_22980978_ChIP-Seq_HELA_Human1.92276233
32AR_21572438_ChIP-Seq_LNCaP_Human1.91852429
33TAF15_26573619_Chip-Seq_HEK293_Human1.89984079
34PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.87722744
35RNF2_27304074_Chip-Seq_NSC_Mouse1.78653110
36* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77714248
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76879901
38REST_18959480_ChIP-ChIP_MESCs_Mouse1.71166310
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.68648712
40* RARB_27405468_Chip-Seq_BRAIN_Mouse1.66852791
41TP63_19390658_ChIP-ChIP_HaCaT_Human1.62804060
42HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.62092536
43EWS_26573619_Chip-Seq_HEK293_Human1.58578824
44* P300_19829295_ChIP-Seq_ESCs_Human1.58237468
45RING1B_27294783_Chip-Seq_ESCs_Mouse1.54749972
46* IGF1R_20145208_ChIP-Seq_DFB_Human1.54209848
47TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51769436
48POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.51769436
49* SMAD4_21799915_ChIP-Seq_A2780_Human1.51570153
50EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48145689
51MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.47412567
52RING1B_27294783_Chip-Seq_NPCs_Mouse1.46184085
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.45129105
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.40137294
55* SMAD3_21741376_ChIP-Seq_EPCs_Human1.39592133
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37858490
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.32594044
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32324875
59* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31100462
60OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.30767462
61* SOX2_21211035_ChIP-Seq_LN229_Gbm1.29183519
62* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28805163
63KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.28373388
64EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.28303004
65* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26719656
66RBPJ_22232070_ChIP-Seq_NCS_Mouse1.26085181
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.25828821
68YAP1_20516196_ChIP-Seq_MESCs_Mouse1.22393017
69MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.19899331
70MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18367882
71VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18281567
72ERG_21242973_ChIP-ChIP_JURKAT_Human1.16888233
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16330860
74* STAT3_23295773_ChIP-Seq_U87_Human1.15627302
75ARNT_22903824_ChIP-Seq_MCF-7_Human1.15531555
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15484892
77AR_25329375_ChIP-Seq_VCAP_Human1.15308358
78P53_22127205_ChIP-Seq_FIBROBLAST_Human1.14982565
79TP53_20018659_ChIP-ChIP_R1E_Mouse1.14922958
80* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14799226
81* AR_19668381_ChIP-Seq_PC3_Human1.13130792
82* RUNX2_22187159_ChIP-Seq_PCA_Human1.11331329
83AHR_22903824_ChIP-Seq_MCF-7_Human1.10935173
84CBP_20019798_ChIP-Seq_JUKART_Human1.10205046
85IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10205046
86RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.09738278
87FUS_26573619_Chip-Seq_HEK293_Human1.09294022
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09065539
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.08681340
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.08535962
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07969714
92* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07084085
93KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06341263
94VDR_22108803_ChIP-Seq_LS180_Human1.05898980
95CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04290823
96NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03668810
97* TCF4_23295773_ChIP-Seq_U87_Human1.03399172
98STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.03068235
99ZNF274_21170338_ChIP-Seq_K562_Hela1.02458535
100ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01883223
101EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.00851781
102ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00559571
103* IRF1_19129219_ChIP-ChIP_H3396_Human1.00530542
104RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00462226
105GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99719427
106ER_23166858_ChIP-Seq_MCF-7_Human0.99490195
107SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.99262274
108BCAT_22108803_ChIP-Seq_LS180_Human0.98657930
109NANOG_18555785_Chip-Seq_ESCs_Mouse0.98396937
110* SOX9_26525672_Chip-Seq_HEART_Mouse0.97019229
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.96727998
112SMAD4_21741376_ChIP-Seq_HESCs_Human0.96043827
113GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95721616
114TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.94733337
115WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.93728733
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.93568136
117GATA1_26923725_Chip-Seq_HPCs_Mouse0.93446991
118WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92964143
119PCGF2_27294783_Chip-Seq_NPCs_Mouse0.92076696

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.84256486
2MP0004859_abnormal_synaptic_plasticity3.63921939
3MP0000566_synostosis3.38396086
4* MP0000778_abnormal_nervous_system3.11046160
5MP0001984_abnormal_olfaction2.82133308
6MP0003635_abnormal_synaptic_transmissio2.67624956
7MP0005423_abnormal_somatic_nervous2.60377077
8MP0006276_abnormal_autonomic_nervous2.56577783
9MP0010030_abnormal_orbit_morphology2.55158658
10MP0002063_abnormal_learning/memory/cond2.43963016
11MP0004270_analgesia2.40628065
12MP0006292_abnormal_olfactory_placode2.31613841
13MP0005187_abnormal_penis_morphology2.29731260
14MP0008789_abnormal_olfactory_epithelium2.26699300
15MP0000569_abnormal_digit_pigmentation2.25316446
16MP0002184_abnormal_innervation2.25175551
17MP0001486_abnormal_startle_reflex2.25068326
18MP0005394_taste/olfaction_phenotype2.19193405
19MP0005499_abnormal_olfactory_system2.19193405
20MP0001529_abnormal_vocalization2.15391462
21MP0002102_abnormal_ear_morphology2.12023828
22MP0002572_abnormal_emotion/affect_behav2.04499901
23MP0002938_white_spotting1.98290076
24MP0009745_abnormal_behavioral_response1.97902701
25MP0004133_heterotaxia1.90199457
26MP0005248_abnormal_Harderian_gland1.87359732
27MP0002653_abnormal_ependyma_morphology1.83386850
28MP0002064_seizures1.83220586
29MP0002557_abnormal_social/conspecific_i1.82265665
30MP0003890_abnormal_embryonic-extraembry1.76665594
31MP0000537_abnormal_urethra_morphology1.74624677
32MP0009046_muscle_twitch1.67998327
33MP0004742_abnormal_vestibular_system1.62725744
34MP0002734_abnormal_mechanical_nocicepti1.60991197
35MP0004811_abnormal_neuron_physiology1.60861142
36MP0000631_abnormal_neuroendocrine_gland1.58151132
37MP0003122_maternal_imprinting1.54113807
38MP0000955_abnormal_spinal_cord1.51731070
39* MP0002882_abnormal_neuron_morphology1.51118062
40MP0002272_abnormal_nervous_system1.51092346
41MP0005646_abnormal_pituitary_gland1.48479027
42MP0005645_abnormal_hypothalamus_physiol1.46741630
43MP0002067_abnormal_sensory_capabilities1.46741599
44MP0010386_abnormal_urinary_bladder1.46275458
45MP0003787_abnormal_imprinting1.43037713
46* MP0003861_abnormal_nervous_system1.42957545
47MP0001299_abnormal_eye_distance/1.39417325
48MP0005253_abnormal_eye_physiology1.38494637
49MP0004885_abnormal_endolymph1.37436224
50MP0003938_abnormal_ear_development1.37199291
51* MP0002152_abnormal_brain_morphology1.35765602
52MP0002751_abnormal_autonomic_nervous1.33454628
53MP0005386_behavior/neurological_phenoty1.33321611
54MP0004924_abnormal_behavior1.33321611
55MP0001968_abnormal_touch/_nociception1.32479215
56MP0003315_abnormal_perineum_morphology1.28943023
57MP0001502_abnormal_circadian_rhythm1.25900204
58MP0002249_abnormal_larynx_morphology1.23936363
59MP0001440_abnormal_grooming_behavior1.23492450
60MP0008877_abnormal_DNA_methylation1.20169327
61MP0002928_abnormal_bile_duct1.17723972
62MP0004145_abnormal_muscle_electrophysio1.15222393
63MP0003385_abnormal_body_wall1.14600482
64MP0000026_abnormal_inner_ear1.14102240
65MP0009250_abnormal_appendicular_skeleto1.13765711
66MP0000049_abnormal_middle_ear1.12480563
67* MP0002752_abnormal_somatic_nervous1.11227887
68MP0005551_abnormal_eye_electrophysiolog1.11190139
69MP0002909_abnormal_adrenal_gland1.10221242
70MP0002116_abnormal_craniofacial_bone1.09738648
71MP0003755_abnormal_palate_morphology1.09280146
72MP0003121_genomic_imprinting1.08798521
73MP0002733_abnormal_thermal_nociception1.08610378
74MP0002066_abnormal_motor_capabilities/c1.08305815
75MP0004858_abnormal_nervous_system1.05635553
76MP0001188_hyperpigmentation1.02884666
77MP0008569_lethality_at_weaning1.01509997
78MP0003221_abnormal_cardiomyocyte_apopto1.00943963
79MP0001485_abnormal_pinna_reflex1.00904242
80MP0002234_abnormal_pharynx_morphology1.00104374
81MP0001970_abnormal_pain_threshold0.98708194
82* MP0005195_abnormal_posterior_eye0.96617331
83MP0001346_abnormal_lacrimal_gland0.96346254
84MP0001177_atelectasis0.96313063
85MP0001293_anophthalmia0.95598997
86MP0002233_abnormal_nose_morphology0.94257254
87MP0002736_abnormal_nociception_after0.92823771
88MP0006072_abnormal_retinal_apoptosis0.90456630
89MP0003935_abnormal_craniofacial_develop0.89816280
90MP0003567_abnormal_fetal_cardiomyocyte0.89724273
91MP0005391_vision/eye_phenotype0.89427522
92MP0000579_abnormal_nail_morphology0.88779381
93MP0003011_delayed_dark_adaptation0.87176887
94MP0002932_abnormal_joint_morphology0.86027460
95MP0001905_abnormal_dopamine_level0.84654434
96MP0005257_abnormal_intraocular_pressure0.84397678
97MP0002229_neurodegeneration0.83920491
98MP0000647_abnormal_sebaceous_gland0.83859316
99MP0003937_abnormal_limbs/digits/tail_de0.83219756
100* MP0002081_perinatal_lethality0.81983155
101MP0001501_abnormal_sleep_pattern0.81911528
102MP0004142_abnormal_muscle_tone0.81521106
103MP0008995_early_reproductive_senescence0.81401813
104MP0000428_abnormal_craniofacial_morphol0.81343357
105MP0002735_abnormal_chemical_nociception0.79629818
106MP0002638_abnormal_pupillary_reflex0.78842606
107MP0001963_abnormal_hearing_physiology0.78010639
108MP0000538_abnormal_urinary_bladder0.76679425
109MP0005503_abnormal_tendon_morphology0.76530397
110* MP0002069_abnormal_eating/drinking_beha0.76087751
111MP0002822_catalepsy0.75547646
112MP0001943_abnormal_respiration0.75255714
113MP0003942_abnormal_urinary_system0.74738568
114MP0003119_abnormal_digestive_system0.74506929
115MP0001286_abnormal_eye_development0.70584699
116MP0003633_abnormal_nervous_system0.70168035
117MP0003136_yellow_coat_color0.69232463
118MP0002160_abnormal_reproductive_system0.67281429
119MP0005084_abnormal_gallbladder_morpholo0.66441132
120MP0000534_abnormal_ureter_morphology0.63533791

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)4.54924833
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.54924833
3Cortical dysplasia (HP:0002539)4.25424883
4Focal motor seizures (HP:0011153)4.06556873
5Abnormality of the labia minora (HP:0012880)3.86001341
6Hepatoblastoma (HP:0002884)3.79524647
7Gait imbalance (HP:0002141)3.77948948
8Medial flaring of the eyebrow (HP:0010747)3.42391876
9Midline defect of the nose (HP:0004122)3.33661560
10Congenital primary aphakia (HP:0007707)3.32569790
11Trigonocephaly (HP:0000243)3.23453072
12Amyotrophic lateral sclerosis (HP:0007354)3.19055061
13Abnormality of the 4th metacarpal (HP:0010012)3.17311178
14Nephrogenic diabetes insipidus (HP:0009806)3.17262679
15Alacrima (HP:0000522)3.15444001
16True hermaphroditism (HP:0010459)3.08825913
17Pancreatic fibrosis (HP:0100732)3.05734764
18Chronic hepatic failure (HP:0100626)3.04940212
19Epileptic encephalopathy (HP:0200134)3.04750547
20Retinal dysplasia (HP:0007973)3.04328792
21Anteriorly placed anus (HP:0001545)2.99520412
22Pancreatic cysts (HP:0001737)2.98558592
23Nephronophthisis (HP:0000090)2.96844780
24Focal seizures (HP:0007359)2.91235098
25Molar tooth sign on MRI (HP:0002419)2.88420030
26Abnormality of midbrain morphology (HP:0002418)2.88420030
27Decreased lacrimation (HP:0000633)2.84348266
28Genital tract atresia (HP:0001827)2.80044452
29Vaginal atresia (HP:0000148)2.79969451
30Agitation (HP:0000713)2.78776360
31Abnormality of the corticospinal tract (HP:0002492)2.73967321
32Abnormality of the lower motor neuron (HP:0002366)2.73664452
33Hyperventilation (HP:0002883)2.72930680
34Neoplasm of the heart (HP:0100544)2.64382029
35Myokymia (HP:0002411)2.62949844
36Polyphagia (HP:0002591)2.60856788
37Drooling (HP:0002307)2.60708063
38Excessive salivation (HP:0003781)2.60708063
39Polymicrogyria (HP:0002126)2.56131774
40Facial hemangioma (HP:0000329)2.52559551
41Exotropia (HP:0000577)2.52526472
42Lissencephaly (HP:0001339)2.49644163
43Abnormality of the diencephalon (HP:0010662)2.49037896
44Abnormality of the renal medulla (HP:0100957)2.48793335
45Abnormality of the parietal bone (HP:0002696)2.47578817
46Impaired vibration sensation in the lower limbs (HP:0002166)2.46683263
47Poor coordination (HP:0002370)2.45732647
48Abnormality of the aortic arch (HP:0012303)2.44758830
49Febrile seizures (HP:0002373)2.42159008
50Broad-based gait (HP:0002136)2.40952387
51Amblyopia (HP:0000646)2.38782387
52Failure to thrive in infancy (HP:0001531)2.37711580
53Abnormal respiratory epithelium morphology (HP:0012253)2.36237302
54Abnormal respiratory motile cilium morphology (HP:0005938)2.36237302
55Anencephaly (HP:0002323)2.36197954
56Oligodactyly (hands) (HP:0001180)2.32575392
57Growth hormone deficiency (HP:0000824)2.31741466
58Occipital encephalocele (HP:0002085)2.31386906
59Protruding tongue (HP:0010808)2.29652625
60Wide cranial sutures (HP:0010537)2.28675734
61Aplasia/Hypoplasia of the brainstem (HP:0007362)2.28387541
62Hypoplasia of the brainstem (HP:0002365)2.28387541
63Labial hypoplasia (HP:0000066)2.27872015
64Intestinal atresia (HP:0011100)2.26434731
65Postaxial hand polydactyly (HP:0001162)2.24853435
66Epileptiform EEG discharges (HP:0011182)2.23902611
67EEG with generalized epileptiform discharges (HP:0011198)2.23110108
68Limb dystonia (HP:0002451)2.21903469
69Spastic tetraplegia (HP:0002510)2.21440887
70Aqueductal stenosis (HP:0002410)2.21202419
71Anosmia (HP:0000458)2.19801127
72Decreased testicular size (HP:0008734)2.19748855
73Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.15800128
74Wrist flexion contracture (HP:0001239)2.15713797
75Narrow forehead (HP:0000341)2.13048015
76Anophthalmia (HP:0000528)2.12750052
77Abnormality of the astrocytes (HP:0100707)2.10625015
78Astrocytoma (HP:0009592)2.10625015
79Shallow orbits (HP:0000586)2.09514839
80Cystic liver disease (HP:0006706)2.09423167
81Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.09258684
82Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.08792873
83Degeneration of the lateral corticospinal tracts (HP:0002314)2.08792873
84Tubulointerstitial nephritis (HP:0001970)2.08364873
85Micropenis (HP:0000054)2.08331451
86Hypsarrhythmia (HP:0002521)2.08017758
87Sclerocornea (HP:0000647)2.07717901
88Concave nail (HP:0001598)2.07486490
89Oligodactyly (HP:0012165)2.07348761
90Hypoplastic female external genitalia (HP:0012815)2.06733601
91Heterochromia iridis (HP:0001100)2.05861746
92Postaxial foot polydactyly (HP:0001830)2.05210903
93Absent speech (HP:0001344)2.04837740
94Glioma (HP:0009733)2.04332557
95Megalencephaly (HP:0001355)2.01367729
96Progressive cerebellar ataxia (HP:0002073)2.01215804
97Broad foot (HP:0001769)1.99233159
98Optic nerve hypoplasia (HP:0000609)1.98643596
99Morphological abnormality of the middle ear (HP:0008609)1.97699885
100Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.97162539
101Tubulointerstitial abnormality (HP:0001969)1.95131848
102Bilateral microphthalmos (HP:0007633)1.95043588
103Abnormal eating behavior (HP:0100738)1.94986813
104Morphological abnormality of the pyramidal tract (HP:0002062)1.94212838
105Abnormal respiratory motile cilium physiology (HP:0012261)1.92072290
106Truncal ataxia (HP:0002078)1.91802491
107High anterior hairline (HP:0009890)1.91460051
108Congenital stationary night blindness (HP:0007642)1.91370619
109Abnormality of salivation (HP:0100755)1.91021273
110Medulloblastoma (HP:0002885)1.90616076
111Type II lissencephaly (HP:0007260)1.89586934
112Septo-optic dysplasia (HP:0100842)1.89415829
113Abnormality of the intervertebral disk (HP:0005108)1.88668863
114Abnormal ciliary motility (HP:0012262)1.88230173
115Sleep apnea (HP:0010535)1.87423999
116Hypoplastic nipples (HP:0002557)1.87144627
117Aplasia/Hypoplasia of the lens (HP:0008063)1.86604260
118Open mouth (HP:0000194)1.86308071
119Nasolacrimal duct obstruction (HP:0000579)1.86270865
120Aplasia/Hypoplasia of the sternum (HP:0006714)1.86058338
121Abnormal hair whorl (HP:0010721)1.85077984
122Thyroid-stimulating hormone excess (HP:0002925)1.84256628
123Shawl scrotum (HP:0000049)1.83451761
124Aplasia/Hypoplasia of the tongue (HP:0010295)1.83361080
125Pachygyria (HP:0001302)1.83155068
126Inability to walk (HP:0002540)1.83080134
127Visual hallucinations (HP:0002367)1.82661010
128Renal hypoplasia (HP:0000089)1.82606925
129Preaxial hand polydactyly (HP:0001177)1.82555615
130Hip dysplasia (HP:0001385)1.82351112
131Atrophy/Degeneration involving motor neurons (HP:0007373)1.82255709
132Absence seizures (HP:0002121)1.80962979
133Abnormality of the metopic suture (HP:0005556)1.80266778
134Esotropia (HP:0000565)1.79021332
135Abnormality of the lacrimal duct (HP:0011481)1.79011308
136Patellar aplasia (HP:0006443)1.78865991
137Shoulder girdle muscle weakness (HP:0003547)1.78776592
138Generalized tonic-clonic seizures (HP:0002069)1.76490986
139Scrotal hypoplasia (HP:0000046)1.76231145
140Vitreoretinal degeneration (HP:0000655)1.76014034
141Abnormality of the nasal septum (HP:0000419)1.75994311
142Hyperglycinemia (HP:0002154)1.75517351
143Keratoconus (HP:0000563)1.74961015
144Increased corneal curvature (HP:0100692)1.74961015
145Blue irides (HP:0000635)1.74518148
146Intellectual disability, moderate (HP:0002342)1.74306467
147Thickened helices (HP:0000391)1.72743638
148Hypoplasia of the corpus callosum (HP:0002079)1.69960002
149Autism (HP:0000717)1.69951847
150Cutaneous finger syndactyly (HP:0010554)1.69942628
151Abnormality of the nasolacrimal system (HP:0000614)1.69460421
152Split foot (HP:0001839)1.69128589
153Specific learning disability (HP:0001328)1.68157737
154Short phalanx of the thumb (HP:0009660)1.67378807
155Urinary bladder sphincter dysfunction (HP:0002839)1.67287117
156Choanal stenosis (HP:0000452)1.67192884
157Heterotopia (HP:0002282)1.66730389
158Ankle clonus (HP:0011448)1.66699351
159Stereotypic behavior (HP:0000733)1.66623890
160Tented upper lip vermilion (HP:0010804)1.65297012

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.56183562
2KSR13.93499144
3TRIM283.18907046
4NTRK33.00154075
5EPHB22.75180873
6SIK32.66525887
7FGFR22.55683511
8CASK2.53269200
9NTRK22.53131376
10EPHA42.36323547
11PRPF4B2.31647887
12DYRK22.30895419
13MAP4K22.28289127
14MAPK132.15713448
15BCR2.09747575
16MAP3K41.94474078
17MAP3K91.92113593
18MINK11.91554662
19ERBB31.89140436
20PINK11.76523881
21UHMK11.68788983
22TNIK1.64696259
23ICK1.62519889
24PAK61.60432516
25MAP2K71.56012914
26DYRK1B1.48896547
27SIK21.44072643
28WNK31.31337125
29DAPK21.28749846
30PNCK1.28503962
31ADRBK21.27047431
32CDK51.18483153
33SGK4941.18441415
34SGK2231.18441415
35RPS6KA41.14191968
36FRK1.13781647
37TYRO31.12535816
38DYRK1A1.04479679
39FGFR11.02805489
40CSNK1G21.01698342
41SGK20.99758044
42CSNK1G30.99399011
43CAMK1G0.99288560
44ERBB20.99182132
45CAMKK20.98472054
46MAP2K40.97987718
47CSNK1A1L0.96843998
48KSR20.95140885
49BMPR1B0.93839424
50MAP3K120.89113825
51CDK180.88214439
52BCKDK0.87051372
53MAP3K60.85274244
54TAOK20.84200966
55LIMK10.83464190
56BRD40.83384837
57MAPK150.81732748
58WNK40.80571030
59IRAK20.74342548
60CDK150.74147746
61CDK190.73916583
62STK110.73640654
63CDK140.71784073
64CSNK1G10.71749731
65PHKG10.69187989
66PHKG20.69187989
67PDGFRA0.68347179
68YES10.68304557
69PRKCG0.68123707
70CCNB10.66403856
71MARK20.65885782
72NEK60.64262244
73INSRR0.64242053
74ADRBK10.63021974
75GRK10.62833519
76PRKCE0.61945339
77CDK11A0.60827684
78PRKD30.60022609
79PAK30.59718296
80PRKCZ0.59658348
81ROCK10.59628933
82SGK10.59288332
83SGK30.59276805
84DAPK10.58768350
85CAMK2A0.58063548
86SRPK10.57643314
87PLK20.56152035
88CAMK2B0.55924293
89OXSR10.55884068
90RET0.54267805
91CDK30.54123791
92EPHB10.53720846
93MAPK90.52513388
94CAMK40.51183538
95AKT30.50430453
96LATS10.49826419
97ROCK20.47553326
98PKN10.46624598
99CAMK10.46059809
100ERBB40.45667947
101MAPK80.42986540
102RPS6KA20.42747655
103MAPK100.42664111
104CAMKK10.41258528
105GSK3B0.40933815
106PRKAA10.40814548
107EPHA30.40056366
108PRKACA0.39790797
109DDR20.39663754
110DYRK30.39471550
111LATS20.38347716
112STK38L0.37539817
113PRKG10.36569009
114MKNK10.36327434
115CDC42BPA0.35970588
116RPS6KA30.34497565
117NTRK10.34306559
118CSNK1D0.33287657
119PRKCH0.33074613
120CSNK1E0.32843060
121CDK10.32819139
122STK380.32678659
123CSNK1A10.32257952
124STK390.28172596
125MKNK20.28028560
126RPS6KA50.27359769
127PRKACB0.26491204
128CLK10.24791467
129PRKACG0.23154608

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.61869943
2Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005342.85067218
3Synaptic vesicle cycle_Homo sapiens_hsa047212.51444979
4* Axon guidance_Homo sapiens_hsa043602.48166454
5Morphine addiction_Homo sapiens_hsa050322.46196068
6GABAergic synapse_Homo sapiens_hsa047272.38228059
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.36942371
8Olfactory transduction_Homo sapiens_hsa047402.27082726
9Glutamatergic synapse_Homo sapiens_hsa047242.23039629
10Circadian entrainment_Homo sapiens_hsa047132.15538122
11Dopaminergic synapse_Homo sapiens_hsa047282.08736092
12Basal cell carcinoma_Homo sapiens_hsa052172.03096959
13Steroid biosynthesis_Homo sapiens_hsa001001.95729715
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.95635603
15Cocaine addiction_Homo sapiens_hsa050301.95332940
16Cholinergic synapse_Homo sapiens_hsa047251.95332828
17Taste transduction_Homo sapiens_hsa047421.92476943
18Hedgehog signaling pathway_Homo sapiens_hsa043401.85976468
19Amphetamine addiction_Homo sapiens_hsa050311.83407774
20Long-term potentiation_Homo sapiens_hsa047201.64699201
21Renin secretion_Homo sapiens_hsa049241.63897662
22Serotonergic synapse_Homo sapiens_hsa047261.63287779
23Endometrial cancer_Homo sapiens_hsa052131.60041695
24Gap junction_Homo sapiens_hsa045401.56996495
25Butanoate metabolism_Homo sapiens_hsa006501.53296180
26ErbB signaling pathway_Homo sapiens_hsa040121.49664277
27Insulin secretion_Homo sapiens_hsa049111.48738968
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.44438115
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.37988669
30Oxytocin signaling pathway_Homo sapiens_hsa049211.37520955
31Wnt signaling pathway_Homo sapiens_hsa043101.37072551
32Protein export_Homo sapiens_hsa030601.33905703
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33871507
34* Colorectal cancer_Homo sapiens_hsa052101.29476583
35Type II diabetes mellitus_Homo sapiens_hsa049301.27613656
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26848721
37Parkinsons disease_Homo sapiens_hsa050121.25406660
38Long-term depression_Homo sapiens_hsa047301.25125852
39Calcium signaling pathway_Homo sapiens_hsa040201.23682010
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.21043751
41cAMP signaling pathway_Homo sapiens_hsa040241.19665811
42Glioma_Homo sapiens_hsa052141.19338776
43Salivary secretion_Homo sapiens_hsa049701.15842177
44Notch signaling pathway_Homo sapiens_hsa043301.14471683
45Melanogenesis_Homo sapiens_hsa049161.14186564
46Oxidative phosphorylation_Homo sapiens_hsa001901.14144546
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.13567645
48Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.11817840
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.09622138
50Regulation of autophagy_Homo sapiens_hsa041401.07477160
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07303220
52Hippo signaling pathway_Homo sapiens_hsa043901.07093534
53Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.05846997
54Maturity onset diabetes of the young_Homo sapiens_hsa049501.04953450
55Phototransduction_Homo sapiens_hsa047441.03356028
56GnRH signaling pathway_Homo sapiens_hsa049121.02445216
57Gastric acid secretion_Homo sapiens_hsa049711.02368930
58Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.99650738
59Choline metabolism in cancer_Homo sapiens_hsa052310.99008191
60Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.98550577
61Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.96135777
62Alcoholism_Homo sapiens_hsa050340.95472494
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.94564805
64Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93345165
65Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.93096727
66Melanoma_Homo sapiens_hsa052180.92563737
67MAPK signaling pathway_Homo sapiens_hsa040100.91609490
68Ether lipid metabolism_Homo sapiens_hsa005650.89473302
69Huntingtons disease_Homo sapiens_hsa050160.88353812
70Estrogen signaling pathway_Homo sapiens_hsa049150.87292567
71Propanoate metabolism_Homo sapiens_hsa006400.87097013
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86448284
73Linoleic acid metabolism_Homo sapiens_hsa005910.84236328
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83886412
75Oocyte meiosis_Homo sapiens_hsa041140.82136571
76cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81083769
77Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80876428
78Renal cell carcinoma_Homo sapiens_hsa052110.80195423
79Collecting duct acid secretion_Homo sapiens_hsa049660.78119950
80Phospholipase D signaling pathway_Homo sapiens_hsa040720.76681224
81Ras signaling pathway_Homo sapiens_hsa040140.76051085
82Rap1 signaling pathway_Homo sapiens_hsa040150.75075202
83Dilated cardiomyopathy_Homo sapiens_hsa054140.72605143
84mTOR signaling pathway_Homo sapiens_hsa041500.71340098
85VEGF signaling pathway_Homo sapiens_hsa043700.71060713
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.70956446
87Neurotrophin signaling pathway_Homo sapiens_hsa047220.70484867
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.70352677
89Alzheimers disease_Homo sapiens_hsa050100.69006997
90Non-small cell lung cancer_Homo sapiens_hsa052230.68861399
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67179995
92Basal transcription factors_Homo sapiens_hsa030220.67090384
93Circadian rhythm_Homo sapiens_hsa047100.63776538
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.62282005
95Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60061288
96AMPK signaling pathway_Homo sapiens_hsa041520.57154843
97MicroRNAs in cancer_Homo sapiens_hsa052060.56130063
98Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.54992089
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54296419
100Tight junction_Homo sapiens_hsa045300.54078960
101Vibrio cholerae infection_Homo sapiens_hsa051100.53859483
102Cardiac muscle contraction_Homo sapiens_hsa042600.53218578
103Steroid hormone biosynthesis_Homo sapiens_hsa001400.52885277
104Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52652721
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52320684
106Primary bile acid biosynthesis_Homo sapiens_hsa001200.50535284
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.50205370
108Ovarian steroidogenesis_Homo sapiens_hsa049130.49736581
109mRNA surveillance pathway_Homo sapiens_hsa030150.49398731
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.49388775
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47740120
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47705181
113Dorso-ventral axis formation_Homo sapiens_hsa043200.47436383
114Fatty acid metabolism_Homo sapiens_hsa012120.46878158
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.46864403
116Vascular smooth muscle contraction_Homo sapiens_hsa042700.46540599
117Prolactin signaling pathway_Homo sapiens_hsa049170.45805424
118RNA degradation_Homo sapiens_hsa030180.45704987
119* Pathways in cancer_Homo sapiens_hsa052000.45487966
120Central carbon metabolism in cancer_Homo sapiens_hsa052300.44660312
121Prostate cancer_Homo sapiens_hsa052150.44005640
122Insulin signaling pathway_Homo sapiens_hsa049100.42008530
123Peroxisome_Homo sapiens_hsa041460.41018533
124Chronic myeloid leukemia_Homo sapiens_hsa052200.40979505
125Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.40756492
126Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39338936
127Adherens junction_Homo sapiens_hsa045200.39213170
128Phagosome_Homo sapiens_hsa041450.37107719
129Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36710676
130Fatty acid elongation_Homo sapiens_hsa000620.34324302
131Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34244428
132Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.33833450
133Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33810005
134Fat digestion and absorption_Homo sapiens_hsa049750.31903278
135Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.31764014
136Tryptophan metabolism_Homo sapiens_hsa003800.31463107
137ABC transporters_Homo sapiens_hsa020100.30922138

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »