DCHS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1planar cell polarity pathway involved in neural tube closure (GO:0090179)4.53860102
2lateral sprouting from an epithelium (GO:0060601)4.47287640
3regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.32851898
4pyrimidine nucleobase catabolic process (GO:0006208)4.18524613
5axonal fasciculation (GO:0007413)4.16866374
6layer formation in cerebral cortex (GO:0021819)4.10272728
7negative regulation of catenin import into nucleus (GO:0035414)4.09194267
8neuron projection extension involved in neuron projection guidance (GO:1902284)4.01317470
9axon extension involved in axon guidance (GO:0048846)4.01317470
10negative regulation of axon extension involved in axon guidance (GO:0048843)3.99440160
11cell migration in hindbrain (GO:0021535)3.97766091
12central nervous system projection neuron axonogenesis (GO:0021952)3.87105020
13head development (GO:0060322)3.69664908
14negative regulation of axon guidance (GO:1902668)3.63636256
15polarized epithelial cell differentiation (GO:0030859)3.62880721
16regulation of axon extension involved in axon guidance (GO:0048841)3.61619055
17lymphangiogenesis (GO:0001946)3.55645044
18establishment of nucleus localization (GO:0040023)3.49078570
19regulation of axon guidance (GO:1902667)3.42901365
20neuron recognition (GO:0008038)3.40764893
21midgut development (GO:0007494)3.40552407
22vascular endothelial growth factor signaling pathway (GO:0038084)3.38257698
23insulin-like growth factor receptor signaling pathway (GO:0048009)3.37925260
24bone trabecula formation (GO:0060346)3.32261524
25presynaptic membrane assembly (GO:0097105)3.28533211
26postsynaptic membrane organization (GO:0001941)3.27141393
27dendritic spine morphogenesis (GO:0060997)3.26986651
28camera-type eye morphogenesis (GO:0048593)3.26051125
29semaphorin-plexin signaling pathway (GO:0071526)3.25663181
30proximal/distal pattern formation (GO:0009954)3.21280512
31Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.17903864
32blood vessel maturation (GO:0001955)3.17106792
33cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.15598072
34endothelium development (GO:0003158)3.15587752
35nucleobase catabolic process (GO:0046113)3.12855888
36dendrite morphogenesis (GO:0048813)3.12100251
37body morphogenesis (GO:0010171)3.11797078
38regulation of establishment of planar polarity (GO:0090175)3.11027403
39retina vasculature morphogenesis in camera-type eye (GO:0061299)3.10208444
40axon extension (GO:0048675)3.04590429
41presynaptic membrane organization (GO:0097090)3.01117126
42lymph vessel development (GO:0001945)3.00639708
43cardiac myofibril assembly (GO:0055003)2.98714096
44cochlea morphogenesis (GO:0090103)2.97754084
45establishment of tissue polarity (GO:0007164)2.97662830
46establishment of planar polarity (GO:0001736)2.97662830
47paraxial mesoderm development (GO:0048339)2.97437665
48* hippo signaling (GO:0035329)2.96090631
49dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.94186274
50cell proliferation involved in metanephros development (GO:0072203)2.93515951
51central nervous system neuron axonogenesis (GO:0021955)2.91955846
52gastrulation with mouth forming second (GO:0001702)2.91779976
53glial cell proliferation (GO:0014009)2.91157433
54cell migration involved in heart development (GO:0060973)2.89958518
55regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.89745206
56G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.85206080
57convergent extension (GO:0060026)2.83089372
58neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.81439331
59embryonic foregut morphogenesis (GO:0048617)2.77495955
60non-canonical Wnt signaling pathway (GO:0035567)2.77352137
61endothelial cell differentiation (GO:0045446)2.77138710
62cell migration involved in sprouting angiogenesis (GO:0002042)2.76756090
63metanephric mesenchyme development (GO:0072075)2.76691333
64regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.75987308
65mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.75256611
66vocalization behavior (GO:0071625)2.74956333
67collagen fibril organization (GO:0030199)2.72492844
68regulation of catenin import into nucleus (GO:0035412)2.72147557
69hindlimb morphogenesis (GO:0035137)2.72120092
70auditory behavior (GO:0031223)2.71290815
71heart valve formation (GO:0003188)2.70521342
72negative regulation of chondrocyte differentiation (GO:0032331)2.70362125
73neuron cell-cell adhesion (GO:0007158)2.69744301
74positive regulation of glycogen biosynthetic process (GO:0045725)2.69702667
75cerebral cortex radially oriented cell migration (GO:0021799)2.66021587
76mesenchyme morphogenesis (GO:0072132)2.64935115
77cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.64653321
78craniofacial suture morphogenesis (GO:0097094)2.64287768
79kidney mesenchyme development (GO:0072074)2.62894642
80* heart morphogenesis (GO:0003007)2.61964944
81nucleus localization (GO:0051647)2.61784539
82artery development (GO:0060840)2.61708438
83endocardial cushion morphogenesis (GO:0003203)2.61199386
84protein heterotrimerization (GO:0070208)2.60971698
85glomerular filtration (GO:0003094)2.59842221
86Notch signaling involved in heart development (GO:0061314)2.59753565
87collecting duct development (GO:0072044)2.59275443
88respiratory tube development (GO:0030323)2.59237678
89outer ear morphogenesis (GO:0042473)2.57333454
90sequestering of extracellular ligand from receptor (GO:0035581)2.55382706
91chondrocyte proliferation (GO:0035988)2.55299318
92neuron projection extension (GO:1990138)2.52521271
93positive regulation of axon extension (GO:0045773)2.52166547
94regulation of mesenchymal cell proliferation (GO:0010464)2.52143170
95dermatan sulfate metabolic process (GO:0030205)2.52117010
96coronary vasculature morphogenesis (GO:0060977)2.51550632
97peripheral nervous system axon ensheathment (GO:0032292)2.51299723
98myelination in peripheral nervous system (GO:0022011)2.51299723
99neurotransmitter-gated ion channel clustering (GO:0072578)2.51085653
100embryonic hindlimb morphogenesis (GO:0035116)2.50169979
101negative regulation of oligodendrocyte differentiation (GO:0048715)2.49778182
102negative regulation of axon extension (GO:0030517)2.49365175
103ganglion development (GO:0061548)2.48925939
104cranial nerve morphogenesis (GO:0021602)2.47338161
105dermatan sulfate biosynthetic process (GO:0030208)2.47045011
106plasma membrane repair (GO:0001778)2.46596147
107atrial septum morphogenesis (GO:0060413)2.45639327
108cardiac ventricle formation (GO:0003211)2.45377742
109anatomical structure regression (GO:0060033)2.45026056
110renal system development (GO:0072001)2.44813769
111negative chemotaxis (GO:0050919)2.43689425
112regulation of NFAT protein import into nucleus (GO:0051532)2.43031799
113cardiac chamber formation (GO:0003207)2.42625692
114embryonic body morphogenesis (GO:0010172)2.42496852
115positive regulation of mesenchymal cell proliferation (GO:0002053)2.42420635
116regulation of synapse structural plasticity (GO:0051823)2.42358914
117spinal cord development (GO:0021510)2.38532721
118lung-associated mesenchyme development (GO:0060484)2.37754660
119establishment of monopolar cell polarity (GO:0061162)2.37528253
120establishment or maintenance of monopolar cell polarity (GO:0061339)2.37528253
121regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.37320531
122dorsal/ventral axis specification (GO:0009950)2.37288749
123facial nerve structural organization (GO:0021612)2.35937193
124establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.34081810
125collagen catabolic process (GO:0030574)2.32202544
126collagen metabolic process (GO:0032963)2.31761107
127regulation of heart morphogenesis (GO:2000826)2.31505962
128regulation of glycogen (starch) synthase activity (GO:2000465)2.31488515
129mesenchymal cell proliferation (GO:0010463)2.31374955
130endocardial cushion development (GO:0003197)2.31223887
131vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.31113255
132renal filtration (GO:0097205)2.30794642
133mesenchyme development (GO:0060485)2.29225165
134positive regulation of synapse assembly (GO:0051965)2.29164078
135chondrocyte development (GO:0002063)2.28840017
136cell communication by electrical coupling (GO:0010644)2.28785665
137morphogenesis of an epithelial sheet (GO:0002011)2.28168582
138venous blood vessel morphogenesis (GO:0048845)2.27884919
139basement membrane organization (GO:0071711)2.27351467
140developmental cell growth (GO:0048588)2.26207247
141negative regulation of blood vessel endothelial cell migration (GO:0043537)2.25213320
142cytoskeletal anchoring at plasma membrane (GO:0007016)2.22050054
143endothelial cell chemotaxis (GO:0035767)2.21067366
144regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.20348388
145multicellular organismal macromolecule metabolic process (GO:0044259)2.19580466
146cellular response to monoamine stimulus (GO:0071868)2.19131112
147cellular response to catecholamine stimulus (GO:0071870)2.19131112
148patterning of blood vessels (GO:0001569)2.18979884
149regulation of cell migration involved in sprouting angiogenesis (GO:0090049)2.17842048
150retinal ganglion cell axon guidance (GO:0031290)2.17540248
151negative regulation of cartilage development (GO:0061037)2.17523849

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.48489793
2EZH2_27304074_Chip-Seq_ESCs_Mouse3.00489445
3EZH2_18974828_ChIP-Seq_MESCs_Mouse2.75718625
4RNF2_18974828_ChIP-Seq_MESCs_Mouse2.75718625
5EED_16625203_ChIP-ChIP_MESCs_Mouse2.74596670
6STAT6_21828071_ChIP-Seq_BEAS2B_Human2.73078444
7EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.69475329
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.64840598
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.58659221
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.51205856
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.47321775
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.45801206
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41878407
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41163553
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.35835180
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.34657171
17SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.28854978
18PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.27570698
19* RNF2_27304074_Chip-Seq_ESCs_Mouse2.26184821
20WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.25296687
21RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.11908443
22ZFP281_18757296_ChIP-ChIP_E14_Mouse2.11477860
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.11386728
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.09514538
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.98677322
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.95172999
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94795555
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.90976774
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.90087720
30ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.82604656
31RING1B_27294783_Chip-Seq_NPCs_Mouse1.82284518
32RING1B_27294783_Chip-Seq_ESCs_Mouse1.82150765
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.80292512
34TP53_20018659_ChIP-ChIP_R1E_Mouse1.79225271
35DROSHA_22980978_ChIP-Seq_HELA_Human1.79157821
36ISL1_27105846_Chip-Seq_CPCs_Mouse1.77506730
37DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.76861964
38* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.75703368
39TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.75573082
40THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.69870298
41TRIM28_21343339_ChIP-Seq_HEK293_Human1.64981851
42* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.61422464
43WT1_19549856_ChIP-ChIP_CCG9911_Human1.59764523
44ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.59316007
45KDM2B_26808549_Chip-Seq_K562_Human1.56885845
46SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.55834112
47EP300_21415370_ChIP-Seq_HL-1_Mouse1.52391760
48HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.52198358
49ZNF274_21170338_ChIP-Seq_K562_Hela1.51102507
50SALL1_21062744_ChIP-ChIP_HESCs_Human1.48641040
51OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.46728639
52AR_21572438_ChIP-Seq_LNCaP_Human1.44773262
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.43891106
54* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.42496799
55TP63_19390658_ChIP-ChIP_HaCaT_Human1.41859310
56KDM2B_26808549_Chip-Seq_SUP-B15_Human1.34158061
57ERG_21242973_ChIP-ChIP_JURKAT_Human1.33747729
58RARG_19884340_ChIP-ChIP_MEFs_Mouse1.33470491
59GBX2_23144817_ChIP-Seq_PC3_Human1.32769332
60CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.32441765
61PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.31172249
62KDM2B_26808549_Chip-Seq_JURKAT_Human1.23404804
63SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.22386267
64FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.21983243
65NFIB_24661679_ChIP-Seq_LUNG_Mouse1.16886868
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14819579
67CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13538076
68YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11673228
69POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11656400
70AR_19668381_ChIP-Seq_PC3_Human1.09186225
71CTCF_27219007_Chip-Seq_Bcells_Human1.08920755
72CTBP2_25329375_ChIP-Seq_LNCAP_Human1.08447301
73RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.08148386
74NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.08070856
75TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07974388
76AHR_22903824_ChIP-Seq_MCF-7_Human1.07845115
77TCF4_18268006_ChIP-ChIP_LS174T_Human1.07392172
78SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.07131292
79TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.06637940
80MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06198929
81* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05765831
82ARNT_22903824_ChIP-Seq_MCF-7_Human1.04899564
83KDM2B_26808549_Chip-Seq_DND41_Human1.04475910
84MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04429388
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01296286
86POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01296286
87P300_27058665_Chip-Seq_ZR-75-30cells_Human0.99997156
88SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99069844
89RARB_27405468_Chip-Seq_BRAIN_Mouse0.97788122
90BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97240854
91SMAD4_21741376_ChIP-Seq_HESCs_Human0.95687304
92CLOCK_20551151_ChIP-Seq_293T_Human0.95232551
93SMAD3_21741376_ChIP-Seq_EPCs_Human0.94614701
94LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94338862
95SOX2_21211035_ChIP-Seq_LN229_Gbm0.93470658
96STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93334554
97* TP53_23651856_ChIP-Seq_MEFs_Mouse0.92634477
98IKZF1_21737484_ChIP-ChIP_HCT116_Human0.92456429
99KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.92361233
100* REST_21632747_ChIP-Seq_MESCs_Mouse0.92232875
101TBX3_20139965_ChIP-Seq_ESCs_Mouse0.91302674
102RNF2_27304074_Chip-Seq_NSC_Mouse0.90352686
103TBX3_20139965_ChIP-Seq_MESCs_Mouse0.90183098
104* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89426711
105SOX2_16153702_ChIP-ChIP_HESCs_Human0.89294956
106ZFP57_27257070_Chip-Seq_ESCs_Mouse0.88900555
107UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.88892231
108REST_18959480_ChIP-ChIP_MESCs_Mouse0.88705336
109ELK3_25401928_ChIP-Seq_HUVEC_Human0.88433591
110ESR1_20079471_ChIP-ChIP_T-47D_Human0.87553417
111TP53_18474530_ChIP-ChIP_U2OS_Human0.86809731
112NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85895981
113ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.85668907
114DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85505093
115NR3C1_23031785_ChIP-Seq_PC12_Mouse0.85497288
116CTNNB1_20460455_ChIP-Seq_HCT116_Human0.84190968
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.83755469
118SMAD3_21741376_ChIP-Seq_HESCs_Human0.83704851
119SOX9_24532713_ChIP-Seq_HFSC_Mouse0.83474787
120RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.82000663
121NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.81652399
122* SMAD4_21799915_ChIP-Seq_A2780_Human0.81311693

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting3.49015625
2MP0000537_abnormal_urethra_morphology2.99933169
3MP0003385_abnormal_body_wall2.74680385
4MP0010030_abnormal_orbit_morphology2.65861177
5MP0005503_abnormal_tendon_morphology2.54315448
6MP0009053_abnormal_anal_canal2.51157546
7MP0000778_abnormal_nervous_system2.38087011
8MP0004272_abnormal_basement_membrane2.31133875
9MP0003705_abnormal_hypodermis_morpholog2.26047452
10MP0003942_abnormal_urinary_system2.22126250
11MP0005187_abnormal_penis_morphology2.19601438
12MP0008438_abnormal_cutaneous_collagen2.17615445
13MP0000049_abnormal_middle_ear2.17294751
14MP0000534_abnormal_ureter_morphology2.09360890
15MP0010368_abnormal_lymphatic_system2.09264468
16MP0003121_genomic_imprinting2.04466053
17MP0005623_abnormal_meninges_morphology2.04444034
18MP0009250_abnormal_appendicular_skeleto2.00501746
19MP0002249_abnormal_larynx_morphology1.92824944
20MP0003123_paternal_imprinting1.87572050
21MP0002822_catalepsy1.78570016
22MP0005409_darkened_coat_color1.77943335
23MP0000751_myopathy1.73783314
24MP0000569_abnormal_digit_pigmentation1.73420021
25MP0003115_abnormal_respiratory_system1.73306148
26MP0003935_abnormal_craniofacial_develop1.72304350
27MP0004859_abnormal_synaptic_plasticity1.72137611
28MP0003755_abnormal_palate_morphology1.70954735
29MP0002282_abnormal_trachea_morphology1.69742182
30MP0000428_abnormal_craniofacial_morphol1.69473007
31MP0002938_white_spotting1.65614991
32MP0002932_abnormal_joint_morphology1.65501861
33MP0004858_abnormal_nervous_system1.63199456
34MP0005248_abnormal_Harderian_gland1.59928066
35MP0003937_abnormal_limbs/digits/tail_de1.59709463
36MP0000566_synostosis1.56983805
37MP0002116_abnormal_craniofacial_bone1.51329877
38MP0001299_abnormal_eye_distance/1.50593043
39MP0003119_abnormal_digestive_system1.46059809
40MP0000733_abnormal_muscle_development1.43591260
41MP0002233_abnormal_nose_morphology1.42218007
42MP0002653_abnormal_ependyma_morphology1.41319198
43MP0003861_abnormal_nervous_system1.39117836
44MP0009780_abnormal_chondrocyte_physiolo1.33591609
45MP0001879_abnormal_lymphatic_vessel1.32372405
46MP0003279_aneurysm1.31345974
47MP0005076_abnormal_cell_differentiation1.31118496
48MP0005167_abnormal_blood-brain_barrier1.28759255
49MP0004270_analgesia1.26869219
50MP0001849_ear_inflammation1.26859550
51MP0000013_abnormal_adipose_tissue1.26006524
52MP0003283_abnormal_digestive_organ1.25287528
53MP0004233_abnormal_muscle_weight1.24911823
54MP0005508_abnormal_skeleton_morphology1.24110855
55MP0002108_abnormal_muscle_morphology1.23312824
56MP0003567_abnormal_fetal_cardiomyocyte1.22045440
57MP0002184_abnormal_innervation1.21309164
58MP0005275_abnormal_skin_tensile1.20865944
59MP0003938_abnormal_ear_development1.19655421
60MP0004084_abnormal_cardiac_muscle1.18782757
61MP0008789_abnormal_olfactory_epithelium1.16990315
62MP0004134_abnormal_chest_morphology1.16168739
63MP0006276_abnormal_autonomic_nervous1.15485684
64MP0002234_abnormal_pharynx_morphology1.14133890
65MP0002638_abnormal_pupillary_reflex1.13507113
66MP0006054_spinal_hemorrhage1.12337940
67MP0005595_abnormal_vascular_smooth1.11912284
68MP0003137_abnormal_impulse_conducting1.10755245
69MP0004885_abnormal_endolymph1.09306981
70MP0001293_anophthalmia1.08835930
71MP0006138_congestive_heart_failure1.08231117
72MP0003091_abnormal_cell_migration1.07818373
73MP0002127_abnormal_cardiovascular_syste1.07690568
74MP0002081_perinatal_lethality1.07124445
75MP0002896_abnormal_bone_mineralization1.06736600
76MP0002109_abnormal_limb_morphology1.06084259
77MP0000955_abnormal_spinal_cord1.05683893
78MP0000432_abnormal_head_morphology1.05375156
79MP0004145_abnormal_muscle_electrophysio1.05001258
80MP0001958_emphysema1.04588130
81MP0000631_abnormal_neuroendocrine_gland1.04277017
82MP0003941_abnormal_skin_development1.03527795
83MP0002089_abnormal_postnatal_growth/wei1.02831223
84MP0000516_abnormal_urinary_system1.01311012
85MP0005367_renal/urinary_system_phenotyp1.01311012
86MP0002063_abnormal_learning/memory/cond1.00908040
87MP0002152_abnormal_brain_morphology0.98831651
88MP0001270_distended_abdomen0.97053945
89MP0002697_abnormal_eye_size0.96059342
90MP0002837_dystrophic_cardiac_calcinosis0.95899642
91MP0002925_abnormal_cardiovascular_devel0.95878578
92MP0002092_abnormal_eye_morphology0.95705131
93MP0002114_abnormal_axial_skeleton0.95551479
94MP0003315_abnormal_perineum_morphology0.93796932
95MP0003787_abnormal_imprinting0.93335032
96MP0004197_abnormal_fetal_growth/weight/0.93316803
97MP0000163_abnormal_cartilage_morphology0.93074951
98MP0001614_abnormal_blood_vessel0.93010075
99MP0004133_heterotaxia0.91947311
100MP0005257_abnormal_intraocular_pressure0.91811321
101MP0005423_abnormal_somatic_nervous0.91098820
102MP0000767_abnormal_smooth_muscle0.90779676
103MP0000762_abnormal_tongue_morphology0.90052430
104MP0001340_abnormal_eyelid_morphology0.88830156
105MP0009384_cardiac_valve_regurgitation0.88616691
106MP0002177_abnormal_outer_ear0.88362468
107MP0002882_abnormal_neuron_morphology0.87321196
108MP0001286_abnormal_eye_development0.87208240
109MP0002128_abnormal_blood_circulation0.87141260
110MP0004215_abnormal_myocardial_fiber0.86716575
111MP0005369_muscle_phenotype0.86678347
112MP0002085_abnormal_embryonic_tissue0.84971806
113MP0003635_abnormal_synaptic_transmissio0.84894469
114MP0002751_abnormal_autonomic_nervous0.83333313
115MP0004811_abnormal_neuron_physiology0.83255802
116MP0010630_abnormal_cardiac_muscle0.83151953
117MP0000026_abnormal_inner_ear0.82911536
118MP0002734_abnormal_mechanical_nocicepti0.82655563
119MP0002115_abnormal_skeleton_extremities0.82319402
120MP0000462_abnormal_digestive_system0.82063427
121MP0002735_abnormal_chemical_nociception0.80935621
122MP0003948_abnormal_gas_homeostasis0.80864007
123MP0002295_abnormal_pulmonary_circulatio0.80354716
124MP0001502_abnormal_circadian_rhythm0.79325142
125MP0003634_abnormal_glial_cell0.78662146
126MP0000759_abnormal_skeletal_muscle0.76787604
127MP0005620_abnormal_muscle_contractility0.76744396
128MP0001348_abnormal_lacrimal_gland0.76309819
129MP0002572_abnormal_emotion/affect_behav0.74813759
130MP0004087_abnormal_muscle_fiber0.74620614
131MP0001177_atelectasis0.74030018
132MP0001943_abnormal_respiration0.73304558

Predicted human phenotypes

RankGene SetZ-score
1* Short 4th metacarpal (HP:0010044)4.61253091
2* Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.61253091
3Shallow orbits (HP:0000586)4.13016419
4* Abnormality of the 4th metacarpal (HP:0010012)3.90269910
5Renal duplication (HP:0000075)3.63989834
6Midline defect of the nose (HP:0004122)3.28447551
7Broad metatarsal (HP:0001783)3.26419319
8Vitreoretinal degeneration (HP:0000655)3.23415211
9Hepatoblastoma (HP:0002884)3.12855661
10Neonatal short-limb short stature (HP:0008921)3.03853453
11Protrusio acetabuli (HP:0003179)2.96537344
12Lymphangioma (HP:0100764)2.95704965
13Hyperacusis (HP:0010780)2.95516944
14Renovascular hypertension (HP:0100817)2.89707823
15Bladder diverticulum (HP:0000015)2.83957380
16Soft skin (HP:0000977)2.82760775
17Elfin facies (HP:0004428)2.76840368
18Vascular tortuosity (HP:0004948)2.68028643
19Atrophic scars (HP:0001075)2.64658023
20Genu recurvatum (HP:0002816)2.63893939
21Trigonocephaly (HP:0000243)2.62982756
22Asymmetry of the thorax (HP:0001555)2.59558373
23Abnormality of the ischium (HP:0003174)2.58138715
24Ankle contracture (HP:0006466)2.56980938
25Flat cornea (HP:0007720)2.56594332
26Overriding aorta (HP:0002623)2.54039261
27Obstructive sleep apnea (HP:0002870)2.51346787
28Arterial tortuosity (HP:0005116)2.46282955
29Wrist flexion contracture (HP:0001239)2.43798332
30Abnormality of the diencephalon (HP:0010662)2.41980359
31Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.40907201
32Buphthalmos (HP:0000557)2.39228145
33Deviation of the hallux (HP:0010051)2.38759390
34Cerebral aneurysm (HP:0004944)2.37963450
35Coronal craniosynostosis (HP:0004440)2.37219347
36Neoplasm of the heart (HP:0100544)2.33796259
37Abnormality of dentin (HP:0010299)2.32452553
38Spinal rigidity (HP:0003306)2.30825456
39Limited hip movement (HP:0008800)2.27659474
40Hallux valgus (HP:0001822)2.26687837
41Insomnia (HP:0100785)2.24591271
42Abnormality of the calcaneus (HP:0008364)2.18267375
43Bowel diverticulosis (HP:0005222)2.18203412
44Broad toe (HP:0001837)2.17986471
45Thin ribs (HP:0000883)2.16551792
46Overgrowth (HP:0001548)2.14463716
47Ectopia lentis (HP:0001083)2.11917418
48Calcaneovalgus deformity (HP:0001848)2.10725442
49Abnormality of the aortic arch (HP:0012303)2.10267867
50Abnormality of the parietal bone (HP:0002696)2.09609730
51Increased nuchal translucency (HP:0010880)2.07628224
52Mitral valve prolapse (HP:0001634)2.03634332
53Broad ribs (HP:0000885)2.03391863
54Fragile skin (HP:0001030)2.02899961
55Wormian bones (HP:0002645)2.02819142
56* Sacral dimple (HP:0000960)2.01653762
57Premature rupture of membranes (HP:0001788)1.99355831
58Cervical subluxation (HP:0003308)1.98339810
59Shawl scrotum (HP:0000049)1.95365220
60Mitral regurgitation (HP:0001653)1.95354987
61Hypoplasia of the iris (HP:0007676)1.95281299
62Broad thumb (HP:0011304)1.95065394
63Infantile muscular hypotonia (HP:0008947)1.94700373
64Short phalanx of the thumb (HP:0009660)1.94390434
65Mild short stature (HP:0003502)1.94235527
66Ulnar bowing (HP:0003031)1.94055187
67Hyperextensible skin (HP:0000974)1.93504039
68Vertebral arch anomaly (HP:0008438)1.91150038
69Patellar dislocation (HP:0002999)1.91065171
70Morphological abnormality of the middle ear (HP:0008609)1.90945137
71Aortic dissection (HP:0002647)1.90334050
72Narrow palate (HP:0000189)1.89408559
73Pointed chin (HP:0000307)1.88907565
74Turricephaly (HP:0000262)1.88201204
75Broad palm (HP:0001169)1.88053274
76Venous insufficiency (HP:0005293)1.88040374
77Macroorchidism (HP:0000053)1.87847034
78High anterior hairline (HP:0009890)1.87744255
79Tracheomalacia (HP:0002779)1.86875922
80Microglossia (HP:0000171)1.85660531
81Peritonitis (HP:0002586)1.84813545
82Visceral angiomatosis (HP:0100761)1.84692013
83Difficulty running (HP:0009046)1.84243674
84Hypoventilation (HP:0002791)1.83450819
85Cortical dysplasia (HP:0002539)1.82631768
86Mesomelia (HP:0003027)1.81860347
87* Cutaneous finger syndactyly (HP:0010554)1.81380613
88Deformed tarsal bones (HP:0008119)1.81073038
89Abnormality of the pubic bones (HP:0003172)1.80362811
90Aneurysm (HP:0002617)1.80349905
91Type 1 muscle fiber predominance (HP:0003803)1.79748012
92Enlarged penis (HP:0000040)1.79179503
93Broad hallux (HP:0010055)1.79027116
94Abnormality of the distal phalanx of the thumb (HP:0009617)1.78372971
95Broad finger (HP:0001500)1.78291781
96Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.78169376
97* Wide anterior fontanel (HP:0000260)1.78093182
98Distal arthrogryposis (HP:0005684)1.76762096
99Broad phalanges of the hand (HP:0009768)1.76200476
100Mildly elevated creatine phosphokinase (HP:0008180)1.75756392
101Skull defect (HP:0001362)1.75676835
102Arnold-Chiari malformation (HP:0002308)1.75289878
103Laryngomalacia (HP:0001601)1.75182582
104Broad face (HP:0000283)1.74683749
105Round ear (HP:0100830)1.74440882
106Increased variability in muscle fiber diameter (HP:0003557)1.74412272
107Subacute progressive viral hepatitis (HP:0006572)1.74342922
108Dilatation of the ascending aorta (HP:0005111)1.74342077
109Broad long bones (HP:0005622)1.74331027
110Bronchomalacia (HP:0002780)1.74298696
111Blue sclerae (HP:0000592)1.71981656
112Disproportionate tall stature (HP:0001519)1.71838252
113Aplasia involving bones of the upper limbs (HP:0009823)1.71676345
114Aplasia of the phalanges of the hand (HP:0009802)1.71676345
115Aplasia involving bones of the extremities (HP:0009825)1.71676345
116Hemangiomatosis (HP:0007461)1.71469213
117Myotonia (HP:0002486)1.71381876
118Broad phalanx (HP:0006009)1.71191363
119Camptodactyly of toe (HP:0001836)1.70901552
120Aortic regurgitation (HP:0001659)1.70209841
121Omphalocele (HP:0001539)1.70142170
122Germ cell neoplasia (HP:0100728)1.69600537
123Follicular hyperkeratosis (HP:0007502)1.67753912
124Abnormality of skeletal muscle fiber size (HP:0012084)1.66877005
125Chin dimple (HP:0010751)1.66251039
126Supernumerary ribs (HP:0005815)1.66106007
127Preaxial foot polydactyly (HP:0001841)1.66062900
128Aortic aneurysm (HP:0004942)1.63080151
129Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.62653362
130Megalencephaly (HP:0001355)1.62330300
131Short 5th finger (HP:0009237)1.62023812
132Protruding ear (HP:0000411)1.60337183
133Abnormality of the phalanges of the hallux (HP:0010057)1.60303695
134Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.59452517
135Short 1st metacarpal (HP:0010034)1.59452517
136Exostoses (HP:0100777)1.59086105
137Hydroureter (HP:0000072)1.58725716
138Long eyelashes (HP:0000527)1.58012500
139Narrow nasal bridge (HP:0000446)1.57507258
140Abnormal number of incisors (HP:0011064)1.56098775
141Obsessive-compulsive behavior (HP:0000722)1.55943929
142Anophthalmia (HP:0000528)1.55512380
143* Cutaneous syndactyly (HP:0012725)1.55243796
144Megalocornea (HP:0000485)1.53864189
145Hip contracture (HP:0003273)1.53835471
146Increased number of teeth (HP:0011069)1.53314013
147Choanal stenosis (HP:0000452)1.52823768
148Hypoplastic ischia (HP:0003175)1.51715380
149Exotropia (HP:0000577)1.51674235
150* Joint laxity (HP:0001388)1.51618581
151Aqueductal stenosis (HP:0002410)1.49670210
152Fibrous tissue neoplasm (HP:0012316)1.49624115

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.61428796
2EPHB23.85671655
3CASK2.86867817
4TRIB32.72437161
5PDGFRA2.70823863
6EPHA32.29996201
7LATS12.23787240
8LATS22.09579246
9RIPK12.08149436
10DDR22.00312715
11FGFR21.98761826
12ICK1.98129436
13PKN21.93083964
14TTN1.92504709
15DYRK21.92356001
16MAP3K101.90187395
17KSR11.89966232
18ERBB31.82169235
19TIE11.79829430
20SIK11.78323262
21NTRK21.75992808
22PHKG21.72695808
23PHKG11.72695808
24SIK21.67603985
25CAMK1G1.65944687
26TYRO31.48468397
27PRKD31.35875573
28DMPK1.34778512
29ERBB21.31653846
30PTK61.28360213
31FGFR11.26993567
32MAPK131.26098566
33MAP3K61.21025893
34PAK61.20718711
35FGFR41.17851754
36LMTK21.17256314
37SGK2231.16537981
38SGK4941.16537981
39CAMK1D1.14019107
40MINK11.11683707
41SGK21.06443258
42MAP3K71.04530213
43TGFBR11.03414045
44MAP3K41.03249082
45CSNK1A1L1.03085968
46MTOR1.01277706
47TNIK0.98957907
48CDK120.95247904
49PAK30.94943211
50PDGFRB0.94819582
51FES0.93122955
52ROCK10.91031238
53AKT30.90170369
54NTRK30.89067597
55UHMK10.87336842
56EEF2K0.86855393
57FER0.86438124
58PAK20.84988400
59MAPK150.84807384
60MAP3K90.84083515
61RPS6KA20.82665408
62CSNK1G20.80846393
63EPHB10.79998684
64RET0.78674899
65MAP2K70.76857535
66MYLK0.76757678
67PTK20.76073402
68MKNK10.75342099
69SGK30.74451015
70ILK0.73105918
71MAPK70.72787370
72CSNK1G30.72757426
73EPHA40.70644013
74MARK20.68704958
75PNCK0.68473966
76CDC42BPA0.67816464
77CSNK1G10.66827881
78RPS6KC10.64693722
79RPS6KL10.64693722
80DYRK1B0.64668352
81PRKCH0.64328800
82PRKD20.63659247
83KDR0.61728556
84LIMK10.60469959
85NLK0.58293567
86CDK50.56795838
87MAPK90.56355301
88MAP2K40.56310163
89PRKCZ0.56223343
90BRD40.55907063
91CAMK40.55525382
92MAPK120.55153819
93BCR0.54410011
94DAPK20.54238571
95RPS6KA60.53323394
96PTK2B0.53233495
97CAMKK10.52317467
98FGFR30.51675261
99ALK0.50698302
100TGFBR20.50377900
101ROCK20.49371075
102CDK140.49118432
103CAMK10.48758155
104CDK180.48205206
105MAPK80.48012447
106NTRK10.47712538
107CDK150.47355585
108PRKD10.47333856
109MKNK20.47287318
110WNK30.46597815
111DYRK1A0.45901848
112PAK40.44444989
113BMX0.42593277
114CDK30.41635281
115STK110.40983917
116ADRBK10.40241203
117PKN10.40054534
118SRC0.39470918
119PLK20.39347441
120PRKAA10.39229438
121CDK11A0.38991086
122MAPK100.38398439
123TAOK10.36953526
124GSK3A0.36816009
125INSRR0.36767213
126HIPK20.36465496
127MAPK40.35779517
128MOS0.35714594
129FYN0.33429308

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052173.09665947
2Axon guidance_Homo sapiens_hsa043602.75505490
3Hedgehog signaling pathway_Homo sapiens_hsa043402.48327046
4Hippo signaling pathway_Homo sapiens_hsa043902.02956326
5Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.94407590
6Notch signaling pathway_Homo sapiens_hsa043301.83586460
7Dilated cardiomyopathy_Homo sapiens_hsa054141.73913833
8Colorectal cancer_Homo sapiens_hsa052101.71998311
9Endometrial cancer_Homo sapiens_hsa052131.70439536
10ECM-receptor interaction_Homo sapiens_hsa045121.68995341
11Wnt signaling pathway_Homo sapiens_hsa043101.65588504
12Focal adhesion_Homo sapiens_hsa045101.64614125
13Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.64306120
14Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.61559850
15Adherens junction_Homo sapiens_hsa045201.59627648
16Melanogenesis_Homo sapiens_hsa049161.57952923
17Viral myocarditis_Homo sapiens_hsa054161.55797130
18Gap junction_Homo sapiens_hsa045401.51670107
19Proteoglycans in cancer_Homo sapiens_hsa052051.48949448
20Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.46147519
21Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.45435853
22MicroRNAs in cancer_Homo sapiens_hsa052061.44333681
23Glioma_Homo sapiens_hsa052141.39008376
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.38409643
25Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.38071409
26Circadian entrainment_Homo sapiens_hsa047131.30351403
27Thyroid hormone signaling pathway_Homo sapiens_hsa049191.29664151
28Estrogen signaling pathway_Homo sapiens_hsa049151.27631077
29Chronic myeloid leukemia_Homo sapiens_hsa052201.24441395
30Dorso-ventral axis formation_Homo sapiens_hsa043201.23423578
31Renal cell carcinoma_Homo sapiens_hsa052111.21963551
32Lysine degradation_Homo sapiens_hsa003101.21147038
33Renin secretion_Homo sapiens_hsa049241.17474089
34Cocaine addiction_Homo sapiens_hsa050301.14612131
35TGF-beta signaling pathway_Homo sapiens_hsa043501.14598655
36Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.14050937
37Aldosterone synthesis and secretion_Homo sapiens_hsa049251.12681667
38Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.12338642
39Cholinergic synapse_Homo sapiens_hsa047251.10105231
40Neurotrophin signaling pathway_Homo sapiens_hsa047221.08550734
41Protein digestion and absorption_Homo sapiens_hsa049741.08197143
42Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.07620219
43Dopaminergic synapse_Homo sapiens_hsa047281.07488506
44Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.07120300
45Pathways in cancer_Homo sapiens_hsa052001.06676330
46mTOR signaling pathway_Homo sapiens_hsa041501.06148476
47Rap1 signaling pathway_Homo sapiens_hsa040151.05620875
48AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.05494341
49ErbB signaling pathway_Homo sapiens_hsa040121.04003888
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03847740
51Type II diabetes mellitus_Homo sapiens_hsa049301.03749316
52Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.02865388
53Tight junction_Homo sapiens_hsa045301.02366575
54Oxytocin signaling pathway_Homo sapiens_hsa049210.99872530
55Glutamatergic synapse_Homo sapiens_hsa047240.96876209
56Longevity regulating pathway - mammal_Homo sapiens_hsa042110.96327529
57GABAergic synapse_Homo sapiens_hsa047270.94348478
58Small cell lung cancer_Homo sapiens_hsa052220.93199911
59Prostate cancer_Homo sapiens_hsa052150.90729968
60GnRH signaling pathway_Homo sapiens_hsa049120.90296866
61Prion diseases_Homo sapiens_hsa050200.89933201
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.89445310
63cAMP signaling pathway_Homo sapiens_hsa040240.88924395
64Melanoma_Homo sapiens_hsa052180.87825503
65Non-small cell lung cancer_Homo sapiens_hsa052230.87159262
66Insulin signaling pathway_Homo sapiens_hsa049100.86082527
67Amoebiasis_Homo sapiens_hsa051460.85039541
68AMPK signaling pathway_Homo sapiens_hsa041520.85033791
69PI3K-Akt signaling pathway_Homo sapiens_hsa041510.84557108
70Gastric acid secretion_Homo sapiens_hsa049710.84126017
71Central carbon metabolism in cancer_Homo sapiens_hsa052300.83916260
72Morphine addiction_Homo sapiens_hsa050320.83254841
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82633434
74Oocyte meiosis_Homo sapiens_hsa041140.82187793
75Insulin secretion_Homo sapiens_hsa049110.81476348
76Nicotine addiction_Homo sapiens_hsa050330.81254095
77Platelet activation_Homo sapiens_hsa046110.80777034
78Prolactin signaling pathway_Homo sapiens_hsa049170.79278358
79Phospholipase D signaling pathway_Homo sapiens_hsa040720.79213267
80Insulin resistance_Homo sapiens_hsa049310.79101126
81Amphetamine addiction_Homo sapiens_hsa050310.79088367
82Long-term potentiation_Homo sapiens_hsa047200.78768756
83Pancreatic cancer_Homo sapiens_hsa052120.78649047
84Taste transduction_Homo sapiens_hsa047420.78631841
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.76748339
86VEGF signaling pathway_Homo sapiens_hsa043700.76412815
87Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.75834531
88HTLV-I infection_Homo sapiens_hsa051660.75478949
89Leukocyte transendothelial migration_Homo sapiens_hsa046700.75336883
90Olfactory transduction_Homo sapiens_hsa047400.75220423
91Alcoholism_Homo sapiens_hsa050340.73961003
92MAPK signaling pathway_Homo sapiens_hsa040100.73689276
93Bladder cancer_Homo sapiens_hsa052190.72063453
94Long-term depression_Homo sapiens_hsa047300.70086499
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69988090
96Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.69660458
97Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.69569283
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.69340912
99Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69024887
100Ras signaling pathway_Homo sapiens_hsa040140.68270368
101Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.67925180
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.67644393
103Ovarian steroidogenesis_Homo sapiens_hsa049130.67047393
104Serotonergic synapse_Homo sapiens_hsa047260.66592593
105mRNA surveillance pathway_Homo sapiens_hsa030150.65249262
106Choline metabolism in cancer_Homo sapiens_hsa052310.63542702
107Glucagon signaling pathway_Homo sapiens_hsa049220.61639080
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.61442071
109Inositol phosphate metabolism_Homo sapiens_hsa005620.60275477
110Salivary secretion_Homo sapiens_hsa049700.60214509
111Calcium signaling pathway_Homo sapiens_hsa040200.57072348
112FoxO signaling pathway_Homo sapiens_hsa040680.54768865

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