DCSTAMP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1oligosaccharide catabolic process (GO:0009313)8.30922337
2glycosphingolipid catabolic process (GO:0046479)8.21151511
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G7.54258990
4glycolipid catabolic process (GO:0019377)7.41187571
5ceramide catabolic process (GO:0046514)6.67178649
6amino sugar catabolic process (GO:0046348)6.57954420
7neutrophil activation involved in immune response (GO:0002283)6.37621774
8* positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)6.04583573
9regulation of cholesterol storage (GO:0010885)5.87340112
10glucosamine-containing compound catabolic process (GO:1901072)5.73166008
11cellular response to thyroid hormone stimulus (GO:0097067)5.48908268
12cellular extravasation (GO:0045123)5.12101650
13positive regulation of monocyte chemotaxis (GO:0090026)4.97927058
14response to peptidoglycan (GO:0032494)4.96922956
15hydrogen peroxide biosynthetic process (GO:0050665)4.86192419
16respiratory burst (GO:0045730)4.79540378
17positive regulation by symbiont of host defense response (GO:0052509)4.75616470
18modulation by symbiont of host defense response (GO:0052031)4.75616470
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.75616470
20modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.75616470
21positive regulation by organism of defense response of other organism involved in symbiotic interact4.75616470
22modulation by symbiont of host immune response (GO:0052553)4.75616470
23immunoglobulin mediated immune response (GO:0016064)4.71590416
24sphingolipid catabolic process (GO:0030149)4.64661814
25membrane lipid catabolic process (GO:0046466)4.61430466
26granulocyte activation (GO:0036230)4.58087002
27superoxide anion generation (GO:0042554)4.49911809
28* osteoclast differentiation (GO:0030316)4.45112268
29positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)4.41492709
30apoptotic cell clearance (GO:0043277)4.40934793
31response to thyroid hormone (GO:0097066)4.39882987
32production of molecular mediator involved in inflammatory response (GO:0002532)4.35522607
33ganglioside metabolic process (GO:0001573)4.32608972
34reactive oxygen species biosynthetic process (GO:1903409)4.29185109
35macrophage activation involved in immune response (GO:0002281)4.28268133
36positive regulation of chemokine biosynthetic process (GO:0045080)4.27822189
37defense response to protozoan (GO:0042832)4.26749281
38neutrophil activation (GO:0042119)4.26333311
39positive regulation of interferon-alpha production (GO:0032727)4.24121069
40regulation of activation of Janus kinase activity (GO:0010533)4.22661014
41lipopolysaccharide-mediated signaling pathway (GO:0031663)4.18316432
42positive regulation of osteoclast differentiation (GO:0045672)4.17975713
43fat-soluble vitamin biosynthetic process (GO:0042362)4.17435733
44* regulation of syncytium formation by plasma membrane fusion (GO:0060142)4.13254620
45cellular response to zinc ion (GO:0071294)4.08499501
46negative regulation of interleukin-17 production (GO:0032700)4.07233638
47T-helper 1 type immune response (GO:0042088)4.04590942
48positive regulation of macrophage derived foam cell differentiation (GO:0010744)4.01296214
49positive regulation of mast cell activation involved in immune response (GO:0033008)4.01018581
50positive regulation of mast cell degranulation (GO:0043306)4.01018581
51positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610814.00337201
52positive regulation of mast cell activation (GO:0033005)3.99036974
53regulation of interferon-alpha production (GO:0032647)3.97814012
54regulation of chemokine biosynthetic process (GO:0045073)3.93990751
55eosinophil chemotaxis (GO:0048245)3.93006100
56regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.92531043
57wound healing, spreading of epidermal cells (GO:0035313)3.91788327
58positive regulation of cellular amide metabolic process (GO:0034250)3.89520308
59pyrimidine-containing compound transmembrane transport (GO:0072531)3.88478462
60regulation of monocyte chemotaxis (GO:0090025)3.84724335
61regulation of interferon-beta biosynthetic process (GO:0045357)3.84069260
62positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.83790094
63barbed-end actin filament capping (GO:0051016)3.81214308
64negative regulation of interleukin-12 production (GO:0032695)3.74512784
65natural killer cell mediated immunity (GO:0002228)3.74092388
66natural killer cell mediated cytotoxicity (GO:0042267)3.74092388
67positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.71257346
68monocyte chemotaxis (GO:0002548)3.70168086
69peptide catabolic process (GO:0043171)3.68824876
70keratan sulfate catabolic process (GO:0042340)3.66942073
71myeloid cell activation involved in immune response (GO:0002275)3.64181163
72positive regulation of type 2 immune response (GO:0002830)3.61482628
73negative regulation of myeloid cell apoptotic process (GO:0033033)3.58740751
74* positive regulation of bone remodeling (GO:0046852)3.58702262
75* positive regulation of bone resorption (GO:0045780)3.58702262
76positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.56075083
77response to protozoan (GO:0001562)3.56031182
78decidualization (GO:0046697)3.54227086
79regulation of macrophage derived foam cell differentiation (GO:0010743)3.53306803
80positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.49531243
81transferrin transport (GO:0033572)3.48490783
82regulation of mononuclear cell migration (GO:0071675)3.48452212
83eosinophil migration (GO:0072677)3.47898643
84intracellular pH reduction (GO:0051452)3.47273174
85positive regulation of interleukin-12 production (GO:0032735)3.45242844
86phagocytosis, recognition (GO:0006910)3.44654678
87B cell mediated immunity (GO:0019724)3.42716909
88leukocyte mediated cytotoxicity (GO:0001909)3.39171474
89response to muramyl dipeptide (GO:0032495)3.38993020
90negative regulation of nitric oxide biosynthetic process (GO:0045019)3.38595603
91lymphocyte chemotaxis (GO:0048247)3.36699583
92macrophage differentiation (GO:0030225)3.34860741
93positive regulation of alpha-beta T cell proliferation (GO:0046641)3.34292661
94pinocytosis (GO:0006907)3.34173140
95iron ion import (GO:0097286)3.31793245
96N-acetylneuraminate metabolic process (GO:0006054)3.31755603
97pH reduction (GO:0045851)3.31580206
98regulation of T-helper 1 cell differentiation (GO:0045625)3.30721676
99positive regulation of cholesterol efflux (GO:0010875)3.28463138
100phagosome maturation (GO:0090382)3.25278877
101positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.25150187
102positive regulation of T-helper cell differentiation (GO:0045624)3.22833620
103granulocyte chemotaxis (GO:0071621)3.22034498
104regulation of mast cell degranulation (GO:0043304)3.21978474
105ferric iron transport (GO:0015682)3.21034068
106trivalent inorganic cation transport (GO:0072512)3.21034068
107leukocyte aggregation (GO:0070486)3.20699355
108positive regulation of interleukin-10 production (GO:0032733)3.18856376
109response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.18444354
110response to host immune response (GO:0052572)3.18444354
111regulation of superoxide anion generation (GO:0032928)3.18083892
112positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)3.17503191
113positive regulation of macrophage cytokine production (GO:0060907)3.16261900
114positive regulation of heat generation (GO:0031652)3.15503391
115regulation of interferon-gamma biosynthetic process (GO:0045072)3.14613585
116negative regulation of lipid storage (GO:0010888)3.14445387
117protein localization to endosome (GO:0036010)3.14395405
118microglial cell activation (GO:0001774)3.13384006
119neutrophil chemotaxis (GO:0030593)3.12549485
120positive regulation of leukocyte degranulation (GO:0043302)3.12388557
121positive regulation of interferon-beta production (GO:0032728)3.12326202
122regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.12270341
123positive regulation of macrophage differentiation (GO:0045651)3.11677695
124regulation of lymphocyte chemotaxis (GO:1901623)3.11572466
125low-density lipoprotein particle remodeling (GO:0034374)3.10945231
126regulation of mast cell activation (GO:0033003)3.10796511
127macrophage activation (GO:0042116)3.10576391
128regulation of fever generation (GO:0031620)3.10181132
129positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.10099618
130detection of molecule of bacterial origin (GO:0032490)3.10014409
131regulation of vitamin D biosynthetic process (GO:0060556)3.09643400
132positive regulation of toll-like receptor signaling pathway (GO:0034123)3.09427632
133granulocyte migration (GO:0097530)3.08448042
134positive regulation of lymphocyte migration (GO:2000403)3.07211724
135positive regulation of gamma-delta T cell activation (GO:0046645)3.05174628
136regulation of interleukin-17 production (GO:0032660)3.04876583
137neutrophil migration (GO:1990266)3.04310722
138response to lipoprotein particle (GO:0055094)3.04299047
139T cell migration (GO:0072678)3.02709331
140regulation of leukocyte degranulation (GO:0043300)3.02183735
141neutrophil mediated immunity (GO:0002446)3.00358771
142positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.99889391
143interferon-gamma-mediated signaling pathway (GO:0060333)2.99406710
144vitamin D metabolic process (GO:0042359)2.98370660
145negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.97934405
146positive regulation of tumor necrosis factor production (GO:0032760)2.97440701
147positive regulation of natural killer cell differentiation (GO:0032825)2.96652020
148positive regulation of interleukin-17 production (GO:0032740)2.95831661
149regulation of alpha-beta T cell proliferation (GO:0046640)2.95462693
150regulation of mast cell activation involved in immune response (GO:0033006)2.95433490
151energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.94613004
152ATP hydrolysis coupled proton transport (GO:0015991)2.94613004
153regulation of interleukin-12 biosynthetic process (GO:0045075)2.94604577
154positive regulation of interleukin-2 production (GO:0032743)2.92992849
155plasma lipoprotein particle clearance (GO:0034381)2.92567553
156positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.90279038
157regulation of hypersensitivity (GO:0002883)2.89250193
158positive regulation of T cell cytokine production (GO:0002726)2.89126979
159positive regulation of cytokine biosynthetic process (GO:0042108)2.88752757
160positive regulation of interleukin-6 production (GO:0032755)2.87722530
161regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.83912148
162positive regulation of sterol transport (GO:0032373)2.81914354
163positive regulation of cholesterol transport (GO:0032376)2.81914354
164positive regulation of antigen processing and presentation (GO:0002579)2.78336078
165regulation of cholesterol esterification (GO:0010872)2.76965063
166lytic vacuole organization (GO:0080171)2.75743773
167lysosome organization (GO:0007040)2.75743773
168phospholipid efflux (GO:0033700)2.73964651
169glucose 6-phosphate metabolic process (GO:0051156)2.71830057
170regulation of macrophage chemotaxis (GO:0010758)2.71671081
171iron ion transport (GO:0006826)2.71591755
172regulation of myeloid leukocyte mediated immunity (GO:0002886)2.69864255
173* positive regulation of tissue remodeling (GO:0034105)2.68905851
174positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.68779695

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse7.75087309
2BP1_19119308_ChIP-ChIP_Hs578T_Human7.67409808
3IRF8_22096565_ChIP-ChIP_GC-B_Human7.42586712
4IRF8_27001747_Chip-Seq_BMDM_Mouse4.70771303
5Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse4.43439602
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.22545458
7SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.11314149
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.78432313
9NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.75149011
10GATA1_22025678_ChIP-Seq_K562_Human3.56327902
11RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.27124766
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.20737706
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.07620499
14MYB_21317192_ChIP-Seq_ERMYB_Mouse2.86095401
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.77967254
16SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.77806987
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.70331700
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.60783216
19STAT4_19710469_ChIP-ChIP_TH1__Mouse2.47865836
20EGR1_19374776_ChIP-ChIP_THP-1_Human2.39944728
21PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.00907320
22SPI1_23547873_ChIP-Seq_NB4_Human1.97344027
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.97024490
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.95495393
25BRD4_27068464_Chip-Seq_AML-cells_Mouse1.90861664
26STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.90603839
27VDR_24787735_ChIP-Seq_THP-1_Human1.86904513
28PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.86021124
29CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.80522808
30CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.77713253
31PU_27001747_Chip-Seq_BMDM_Mouse1.67657797
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.56928977
33CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.55828365
34THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.53855984
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.47016126
36PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.44750810
37CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.44135145
38RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.41688481
39RUNX_20019798_ChIP-Seq_JUKART_Human1.39903991
40NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.39148437
41NRF2_20460467_ChIP-Seq_MEFs_Mouse1.39148437
42MYB_26560356_Chip-Seq_TH2_Human1.38842173
43VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36876149
44VDR_24763502_ChIP-Seq_THP-1_Human1.34681034
45RUNX1_22412390_ChIP-Seq_EML_Mouse1.34488703
46GATA1_19941827_ChIP-Seq_MEL_Mouse1.30969267
47SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.30285749
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26792291
49SPI1_23127762_ChIP-Seq_K562_Human1.26490919
50GATA1_19941826_ChIP-Seq_K562_Human1.21112848
51CDX2_19796622_ChIP-Seq_MESCs_Mouse1.20456823
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17697552
53PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.17439682
54FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.16859662
55LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.15254027
56MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.15060593
57SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14381161
58GATA3_26560356_Chip-Seq_TH2_Human1.13904942
59VDR_21846776_ChIP-Seq_THP-1_Human1.13241989
60PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10665683
61CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09027269
62CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.07970964
63TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.07074407
64TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.04929685
65NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02859096
66MAF_26560356_Chip-Seq_TH1_Human1.01317342
67LXR_22292898_ChIP-Seq_THP-1_Human1.00741257
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00239269
69LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.99761825
70IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99691501
71GATA3_27048872_Chip-Seq_THYMUS_Human0.98238462
72SOX2_20726797_ChIP-Seq_SW620_Human0.96472126
73GATA2_19941826_ChIP-Seq_K562_Human0.95353593
74GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.94890368
75ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.94126794
76KDM2B_26808549_Chip-Seq_SUP-B15_Human0.93515705
77BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.93388895
78STAT6_21828071_ChIP-Seq_BEAS2B_Human0.89427083
79LXR_22158963_ChIP-Seq_LIVER_Mouse0.89062563
80MYB_26560356_Chip-Seq_TH1_Human0.89022172
81STAT1_20625510_ChIP-Seq_HELA_Human0.88064563
82CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.87840187
83EGR1_23403033_ChIP-Seq_LIVER_Mouse0.87567123
84GATA2_22383799_ChIP-Seq_G1ME_Mouse0.87449129
85TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86499991
86RXR_22158963_ChIP-Seq_LIVER_Mouse0.85820314
87GATA2_21666600_ChIP-Seq_HMVEC_Human0.85315681
88SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.84631612
89SCL_19346495_ChIP-Seq_HPC-7_Human0.83926611
90NFIB_24661679_ChIP-Seq_LUNG_Mouse0.83763146
91GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83692497
92ESR1_21235772_ChIP-Seq_MCF-7_Human0.81515479
93CJUN_26792858_Chip-Seq_BT549_Human0.80824356
94GATA1_19941827_ChIP-Seq_MEL86_Mouse0.79480351
95BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.79435003
96PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.79063369
97TP63_17297297_ChIP-ChIP_HaCaT_Human0.77932430
98ESR2_21235772_ChIP-Seq_MCF-7_Human0.77478018
99CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.77468599
100CLOCK_20551151_ChIP-Seq_293T_Human0.77366325
101PPARA_22158963_ChIP-Seq_LIVER_Mouse0.76640539
102TRIM28_21343339_ChIP-Seq_HEK293_Human0.76595488
103JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76332169
104SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.75363262
105SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.72791588
106SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.72791588
107EGR1_19032775_ChIP-ChIP_M12_Human0.72615843
108JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.70901458
109ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.67305258
110SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.66476892
111CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.65554171
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.65021455
113TP53_18474530_ChIP-ChIP_U2OS_Human0.63696085
114SMRT_27268052_Chip-Seq_Bcells_Human0.62909378
115P63_26484246_Chip-Seq_KERATINOCYTES_Human0.62497501
116CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.62466419
117FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.61031569
118KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.60599847
119TFEB_21752829_ChIP-Seq_HELA_Human0.58633818
120SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.58357624
121SALL4_18804426_ChIP-ChIP_XEN_Mouse0.56037542
122GATA3_21867929_ChIP-Seq_TH1_Mouse0.55642920
123RARG_19884340_ChIP-ChIP_MEFs_Mouse0.53962292
124SPI1_20517297_ChIP-Seq_HL60_Human0.51663579
125GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.48163389
126PU.1_20513432_ChIP-Seq_Bcells_Mouse0.47806634
127RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.47506606

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.42430407
2MP0002148_abnormal_hypersensitivity_rea4.41676075
3MP0009785_altered_susceptibility_to4.40308725
4MP0003436_decreased_susceptibility_to4.32777638
5MP0006082_CNS_inflammation3.80276090
6MP0002419_abnormal_innate_immunity3.58854710
7MP0005000_abnormal_immune_tolerance3.49268963
8MP0003303_peritoneal_inflammation3.43643048
9MP0005025_abnormal_response_to3.34072565
10MP0002139_abnormal_hepatobiliary_system3.29003694
11MP0003329_amyloid_beta_deposits3.07630266
12MP0003724_increased_susceptibility_to3.04608045
13MP0005671_abnormal_response_to3.02880806
14MP0002452_abnormal_antigen_presenting2.76638998
15MP0002723_abnormal_immune_serum2.55215214
16MP0005387_immune_system_phenotype2.48352396
17MP0001790_abnormal_immune_system2.48352396
18MP0000685_abnormal_immune_system2.46036830
19MP0004510_myositis2.39837090
20MP0002877_abnormal_melanocyte_morpholog2.35660656
21MP0001853_heart_inflammation2.33846201
22MP0001800_abnormal_humoral_immune2.29528346
23MP0009764_decreased_sensitivity_to2.26601374
24MP0001819_abnormal_immune_cell2.26137563
25MP0002420_abnormal_adaptive_immunity2.19858226
26MP0005058_abnormal_lysosome_morphology2.10528042
27MP0003448_altered_tumor_morphology2.04345918
28MP0002405_respiratory_system_inflammati2.03715999
29MP0001533_abnormal_skeleton_physiology2.03287771
30MP0001845_abnormal_inflammatory_respons1.95425571
31MP0005464_abnormal_platelet_physiology1.94755093
32MP0005166_decreased_susceptibility_to1.90696873
33MP0003075_altered_response_to1.90403070
34MP0000343_altered_response_to1.85766530
35MP0005365_abnormal_bile_salt1.77590572
36MP0009333_abnormal_splenocyte_physiolog1.75793763
37MP0008469_abnormal_protein_level1.72365217
38MP0002006_tumorigenesis1.72229644
39MP0004947_skin_inflammation1.71191731
40MP0005310_abnormal_salivary_gland1.70117081
41MP0002998_abnormal_bone_remodeling1.68716029
42MP0003172_abnormal_lysosome_physiology1.66094686
43MP0010155_abnormal_intestine_physiology1.64117891
44MP0003690_abnormal_glial_cell1.61573259
45MP0003806_abnormal_nucleotide_metabolis1.58122119
46MP0003300_gastrointestinal_ulcer1.55002070
47MP0003186_abnormal_redox_activity1.54316055
48MP0005167_abnormal_blood-brain_barrier1.52392290
49MP0000716_abnormal_immune_system1.46891864
50MP0000858_altered_metastatic_potential1.43305639
51MP0000604_amyloidosis1.33707500
52MP0000569_abnormal_digit_pigmentation1.32219038
53MP0004782_abnormal_surfactant_physiolog1.32119898
54MP0005647_abnormal_sex_gland1.29977272
55MP0010386_abnormal_urinary_bladder1.27278004
56MP0001727_abnormal_embryo_implantation1.25025521
57MP0005164_abnormal_response_to1.24357626
58MP0002398_abnormal_bone_marrow1.24242695
59MP0003191_abnormal_cellular_cholesterol1.20933963
60MP0003632_abnormal_nervous_system1.19468075
61MP0003828_pulmonary_edema1.18784351
62MP0002429_abnormal_blood_cell1.11161296
63MP0005451_abnormal_body_composition1.05376203
64MP0009763_increased_sensitivity_to1.03573568
65MP0001545_abnormal_hematopoietic_system1.01951740
66MP0005397_hematopoietic_system_phenotyp1.01951740
67MP0003634_abnormal_glial_cell1.01788055
68MP0004019_abnormal_vitamin_homeostasis0.99436647
69MP0008260_abnormal_autophagy0.95286679
70MP0005390_skeleton_phenotype0.95140294
71MP0000689_abnormal_spleen_morphology0.93610200
72MP0000681_abnormal_thyroid_gland0.93429566
73MP0002722_abnormal_immune_system0.89884909
74MP0005174_abnormal_tail_pigmentation0.88755620
75MP0003195_calcinosis0.88260230
76MP0000920_abnormal_myelination0.87419190
77MP0003879_abnormal_hair_cell0.85357651
78MP0001851_eye_inflammation0.85304307
79MP0009278_abnormal_bone_marrow0.84300256
80MP0010307_abnormal_tumor_latency0.81964213
81MP0002254_reproductive_system_inflammat0.81470034
82MP0010234_abnormal_vibrissa_follicle0.80998994
83MP0004883_abnormal_blood_vessel0.79682939
84MP0004808_abnormal_hematopoietic_stem0.78583748
85MP0008875_abnormal_xenobiotic_pharmacok0.77663586
86MP0005165_increased_susceptibility_to0.75957412
87MP0002090_abnormal_vision0.75922856
88MP0000249_abnormal_blood_vessel0.74596893
89MP0003631_nervous_system_phenotype0.74217970
90MP0003566_abnormal_cell_adhesion0.73841744
91MP0000015_abnormal_ear_pigmentation0.73647857
92MP0003656_abnormal_erythrocyte_physiolo0.73597115
93MP0000371_diluted_coat_color0.72593520
94MP0005257_abnormal_intraocular_pressure0.71300855
95MP0000372_irregular_coat_pigmentation0.71084883
96MP0002933_joint_inflammation0.70680582
97MP0002896_abnormal_bone_mineralization0.69293004
98MP0003279_aneurysm0.68384320
99MP0004742_abnormal_vestibular_system0.67624438
100MP0003453_abnormal_keratinocyte_physiol0.67103965
101MP0003633_abnormal_nervous_system0.66947294
102MP0009115_abnormal_fat_cell0.66904863
103MP0010329_abnormal_lipoprotein_level0.66893836
104MP0003795_abnormal_bone_structure0.65108239
105MP0002277_abnormal_respiratory_mucosa0.65064109
106MP0003950_abnormal_plasma_membrane0.64511250
107MP0002136_abnormal_kidney_physiology0.63756061
108MP0002166_altered_tumor_susceptibility0.63392805
109MP0010352_gastrointestinal_tract_polyps0.62377155
110MP0006054_spinal_hemorrhage0.60840095
111MP0000465_gastrointestinal_hemorrhage0.60492078
112MP0005076_abnormal_cell_differentiation0.60005080
113MP0000609_abnormal_liver_physiology0.58756732
114MP0003705_abnormal_hypodermis_morpholog0.58741088
115MP0002332_abnormal_exercise_endurance0.56601812
116MP0002295_abnormal_pulmonary_circulatio0.56189406
117MP0003091_abnormal_cell_migration0.55897420
118MP0002693_abnormal_pancreas_physiology0.54752288
119MP0001663_abnormal_digestive_system0.54716138
120MP0002138_abnormal_hepatobiliary_system0.54671657
121MP0005535_abnormal_body_temperature0.53213020
122MP0005171_absent_coat_pigmentation0.52018955
123MP0009840_abnormal_foam_cell0.51977261
124MP0003866_abnormal_defecation0.49665617
125MP0004130_abnormal_muscle_cell0.48765326
126MP0008873_increased_physiological_sensi0.47615986
127MP0005319_abnormal_enzyme/_coenzyme0.43813685
128MP0001881_abnormal_mammary_gland0.43429805

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)8.29422484
2Recurrent abscess formation (HP:0002722)8.22061513
3Recurrent gram-negative bacterial infections (HP:0005420)7.68490793
4Recurrent bacterial skin infections (HP:0005406)7.65152359
5Mediastinal lymphadenopathy (HP:0100721)6.20702908
6Abnormality of macrophages (HP:0004311)5.79487022
7Vacuolated lymphocytes (HP:0001922)4.92719272
8Recurrent skin infections (HP:0001581)4.87791865
9Gingivitis (HP:0000230)4.86506268
10Chronic obstructive pulmonary disease (HP:0006510)4.20584336
11Obstructive lung disease (HP:0006536)4.20584336
12Recurrent fungal infections (HP:0002841)4.19289709
13Stomatitis (HP:0010280)4.18154897
14Autoimmune thrombocytopenia (HP:0001973)4.05551370
15Neurofibrillary tangles (HP:0002185)4.03114319
16Optic neuritis (HP:0100653)3.90102528
17Retrobulbar optic neuritis (HP:0100654)3.90102528
18Orchitis (HP:0100796)3.86767097
19Axonal loss (HP:0003447)3.85364629
20Elevated erythrocyte sedimentation rate (HP:0003565)3.78850757
21Myositis (HP:0100614)3.77002434
22Abnormality of mucopolysaccharide metabolism (HP:0011020)3.69564858
23Abnormality of polysaccharide metabolism (HP:0011012)3.69564858
24Abnormality of glycosaminoglycan metabolism (HP:0004371)3.69564858
25Chronic mucocutaneous candidiasis (HP:0002728)3.66002199
26Recurrent cutaneous fungal infections (HP:0011370)3.66002199
27Increased IgM level (HP:0003496)3.63692484
28Disinhibition (HP:0000734)3.61815434
29Increased cerebral lipofuscin (HP:0011813)3.60259554
30Mucopolysacchariduria (HP:0008155)3.58021155
31Urinary glycosaminoglycan excretion (HP:0003541)3.58021155
32Basal ganglia calcification (HP:0002135)3.53971784
33Vasculitis (HP:0002633)3.52582807
34Gastrointestinal infarctions (HP:0005244)3.51857336
35Systemic lupus erythematosus (HP:0002725)3.51453839
36Apathy (HP:0000741)3.49277743
37Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.47561165
38Diminished motivation (HP:0000745)3.47336632
39Increased neuronal autofluorescent lipopigment (HP:0002074)3.36756324
40Cellulitis (HP:0100658)3.28115386
41Metaphyseal irregularity (HP:0003025)3.27266196
42Mutism (HP:0002300)3.25227133
43Prostate neoplasm (HP:0100787)3.22145348
44Abnormality of glycolipid metabolism (HP:0010969)3.18637607
45Abnormality of liposaccharide metabolism (HP:0010968)3.18637607
46Abnormality of glycosphingolipid metabolism (HP:0004343)3.18637607
47Recurrent viral infections (HP:0004429)3.18262707
48Thick nail (HP:0001805)3.16483841
49Interstitial pulmonary disease (HP:0006530)3.03778986
50Hemoptysis (HP:0002105)2.96511038
51Periodontitis (HP:0000704)2.96239027
52Pustule (HP:0200039)2.94182421
53Cerebral inclusion bodies (HP:0100314)2.93308529
54Xanthomatosis (HP:0000991)2.92201240
55Urticaria (HP:0001025)2.92108955
56Recurrent pneumonia (HP:0006532)2.91841958
57Abnormality of the periventricular white matter (HP:0002518)2.88667951
58Pulmonary infiltrates (HP:0002113)2.86677610
59Protuberant abdomen (HP:0001538)2.80254496
60Agnosia (HP:0010524)2.73260152
61Meningitis (HP:0001287)2.66798554
62Joint hemorrhage (HP:0005261)2.60335214
63Osteomyelitis (HP:0002754)2.60171517
64Neuronal loss in central nervous system (HP:0002529)2.54283837
65Nuclear cataract (HP:0100018)2.54206624
66Poor head control (HP:0002421)2.51387809
67Glomerulonephritis (HP:0000099)2.48626731
68Skin nodule (HP:0200036)2.47440801
69Gangrene (HP:0100758)2.47380383
70Recurrent lower respiratory tract infections (HP:0002783)2.46534051
71Global brain atrophy (HP:0002283)2.45149593
72Hypergammaglobulinemia (HP:0010702)2.44434181
73Multiple enchondromatosis (HP:0005701)2.42729428
74Tetraparesis (HP:0002273)2.41912883
75Arterial thrombosis (HP:0004420)2.41055565
76Hepatosplenomegaly (HP:0001433)2.40992396
77Cheilitis (HP:0100825)2.40341972
78Premature loss of primary teeth (HP:0006323)2.38033556
79Myocardial infarction (HP:0001658)2.37175322
80Gingival bleeding (HP:0000225)2.35757888
81Asymmetric septal hypertrophy (HP:0001670)2.34103237
82Epidermoid cyst (HP:0200040)2.32094012
83Leukocytosis (HP:0001974)2.28904146
84Progressive neurologic deterioration (HP:0002344)2.26881016
85Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.25022958
86Dementia (HP:0000726)2.20625776
87Abnormality of T cell number (HP:0011839)2.20403186
88Upper motor neuron abnormality (HP:0002127)2.19991048
89Paralysis (HP:0003470)2.19617376
90Increased CSF protein (HP:0002922)2.18948869
91Keratoconjunctivitis sicca (HP:0001097)2.16556424
92Sepsis (HP:0100806)2.15922962
93Anorexia (HP:0002039)2.14411088
94Personality changes (HP:0000751)2.11294440
95J-shaped sella turcica (HP:0002680)2.09652069
96Cardiomegaly (HP:0001640)2.09108636
97Retinal atrophy (HP:0001105)2.08976925
98Dysostosis multiplex (HP:0000943)2.08518862
99Abnormality of the pericardium (HP:0001697)2.08324375
100Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.08236444
101Prolonged neonatal jaundice (HP:0006579)2.06663794
102Petechiae (HP:0000967)2.05181652
103Nausea (HP:0002018)2.01772788
104Supranuclear gaze palsy (HP:0000605)2.00512754
105Arthralgia (HP:0002829)2.00257988
106Joint swelling (HP:0001386)1.99148230
107Bone pain (HP:0002653)1.97956798
108Purpura (HP:0000979)1.97513128
109Keratoconjunctivitis (HP:0001096)1.96930589
110Increased serum ferritin (HP:0003281)1.96907317
111Neoplasm of head and neck (HP:0012288)1.96876419
112Esophageal neoplasm (HP:0100751)1.96876419
113Inappropriate behavior (HP:0000719)1.96010292
114Thoracic kyphosis (HP:0002942)1.94891183
115T lymphocytopenia (HP:0005403)1.93702413
116Generalized aminoaciduria (HP:0002909)1.92323263
117Porencephaly (HP:0002132)1.90769919
118Segmental peripheral demyelination/remyelination (HP:0003481)1.90589904
119Skin ulcer (HP:0200042)1.90108584
120Multiple lipomas (HP:0001012)1.88409783
121Abnormality of the vasculature of the conjunctiva (HP:0008054)1.86149625
122Hypercholesterolemia (HP:0003124)1.85799777
123Hyperventilation (HP:0002883)1.85344255
124Parakeratosis (HP:0001036)1.85021398
125Nephritis (HP:0000123)1.84854994
126Amaurosis fugax (HP:0100576)1.84496087
127Pathologic fracture (HP:0002756)1.82758717
128Thin bony cortex (HP:0002753)1.82576517
129Abnormality of the prostate (HP:0008775)1.81760197
130Abnormality of the pleura (HP:0002103)1.81330371
131Esophageal varix (HP:0002040)1.79667960
132Progressive visual loss (HP:0000529)1.77542079
133Chest pain (HP:0100749)1.77185873
134Abnormality of the endocardium (HP:0004306)1.76802848
135Gastrointestinal stroma tumor (HP:0100723)1.76101159
136Osteolytic defects of the phalanges of the hand (HP:0009771)1.76096878
137Osteolytic defects of the hand bones (HP:0009699)1.76096878
138Loss of speech (HP:0002371)1.72757381
139Peripheral demyelination (HP:0011096)1.70650173
140Autoimmune hemolytic anemia (HP:0001890)1.70042297
141Abnormality of the lumbar spine (HP:0100712)1.68742284
142Spinal muscular atrophy (HP:0007269)1.66267658
143Peripheral hypomyelination (HP:0007182)1.64611396
144Steatorrhea (HP:0002570)1.63176245
145Distal lower limb muscle weakness (HP:0009053)1.57656890
146Ovoid vertebral bodies (HP:0003300)1.56449459
147Hypophosphatemia (HP:0002148)1.55235562
148Vertebral compression fractures (HP:0002953)1.54697219
149Abnormality of iron homeostasis (HP:0011031)1.53309085

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK45.88594464
2PBK5.85958151
3BLK4.31588383
4MAP3K144.28533608
5TBK13.30714732
6IRAK42.89905402
7PDK22.86453942
8ACVR1B2.63210133
9TYK22.62371269
10JAK32.48447726
11IRAK32.39917650
12CAMKK22.38967653
13IKBKB2.29505145
14CAMK1D2.18095970
15PIM22.11918925
16NME22.08258711
17TXK1.88033122
18JAK11.80150519
19MST1R1.77729441
20IKBKE1.76491102
21MAP4K11.73357768
22NEK91.66907837
23LIMK11.64435762
24DDR21.62575858
25MAP2K31.59204377
26TAOK21.58774622
27MAP3K31.57562187
28ABL21.57512059
29BMX1.52325592
30MST41.50030071
31KIT1.49369370
32GRK71.46719446
33CAMK1G1.43903173
34FGR1.41202322
35CSK1.40658538
36TESK21.40098044
37SYK1.37027548
38BMPR21.37007479
39CHUK1.23699611
40DAPK21.21202796
41LYN1.20018573
42PRPF4B1.19650861
43STK41.19505258
44MATK1.19396096
45JAK21.19314339
46HCK1.15586155
47ERBB31.15101029
48CDC42BPA1.10829625
49PAK41.10033549
50MAP3K131.08972360
51RPS6KA41.08759449
52YES11.07998345
53ADRBK21.06528914
54ERN11.04843098
55ZAP701.02534951
56RPS6KA21.01637594
57BTK1.00870907
58TRPM70.94440444
59LCK0.93634346
60MARK30.93237281
61PIM10.89706921
62CSF1R0.89368911
63PRKCD0.86990162
64ARAF0.85486737
65MAPK120.84215489
66IRAK10.83297271
67EIF2AK20.83147257
68TAOK30.80394867
69IRAK20.80049714
70TEC0.80014474
71EPHB10.75892602
72SGK30.73598810
73MAP3K120.71302550
74TAOK10.70745824
75RPS6KC10.70012971
76RPS6KL10.70012971
77ERBB40.69191922
78ABL10.66375551
79CLK10.66241672
80EPHA30.65321829
81FGFR30.61707553
82MAP2K60.61383070
83EGFR0.60954041
84MAP3K80.58411287
85CAMKK10.58350844
86PRKCQ0.57323123
87CAMK40.57075243
88MAP3K50.56570868
89SIK30.56540545
90MET0.55862276
91PRKG20.55823788
92SIK20.51802792
93SGK20.49924859
94RIPK10.46975765
95TGFBR20.46108678
96MAP3K110.44625035
97PDGFRB0.43710756
98STK30.42887645
99KSR10.42223793
100MAP3K90.40147486
101MAPK40.38992422
102GSK3A0.38632390
103FES0.38151758
104STK240.36149008
105FGFR40.36076637
106FYN0.35180942
107DAPK30.33987276
108NEK60.33165912
109MAPK70.33125748
110PRKACB0.33026970
111PDPK10.32579892
112MAP3K60.32398909
113PDK10.30977226
114MOS0.29195538
115ITK0.28444393
116STK100.26942425
117MAP3K10.23848957
118INSR0.23812321
119MUSK0.22936847
120IGF1R0.22783688
121BMPR1B0.22332699
122PRKCE0.22202360
123LRRK20.21207869
124NLK0.20800559
125PIK3CG0.19945494
126CDK60.19604898
127KSR20.18344009
128PRKCH0.18269739
129SRC0.17919702
130SCYL20.17372211
131TESK10.17213341
132MAPKAPK20.17176566
133TTN0.15532466
134PTK60.13476501
135MAP3K20.11104893
136RPS6KA60.10447556

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.99105115
2Leishmaniasis_Homo sapiens_hsa051403.42558868
3Allograft rejection_Homo sapiens_hsa053303.15622327
4Rheumatoid arthritis_Homo sapiens_hsa053232.92102186
5Legionellosis_Homo sapiens_hsa051342.90811107
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.84602018
7Type I diabetes mellitus_Homo sapiens_hsa049402.77439113
8Staphylococcus aureus infection_Homo sapiens_hsa051502.76484655
9Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.63057256
10Tuberculosis_Homo sapiens_hsa051522.58520476
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.55219476
12Malaria_Homo sapiens_hsa051442.53270425
13Pertussis_Homo sapiens_hsa051332.43903747
14NOD-like receptor signaling pathway_Homo sapiens_hsa046212.39633285
15Phagosome_Homo sapiens_hsa041452.28686918
16Asthma_Homo sapiens_hsa053102.28353423
17Osteoclast differentiation_Homo sapiens_hsa043802.21861069
18African trypanosomiasis_Homo sapiens_hsa051432.15423521
19Primary bile acid biosynthesis_Homo sapiens_hsa001202.12838756
20Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.04110409
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.03174287
22Lysosome_Homo sapiens_hsa041421.91285930
23Measles_Homo sapiens_hsa051621.91100883
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.90699510
25Salmonella infection_Homo sapiens_hsa051321.87628249
26TNF signaling pathway_Homo sapiens_hsa046681.82783128
27Intestinal immune network for IgA production_Homo sapiens_hsa046721.74397503
28Collecting duct acid secretion_Homo sapiens_hsa049661.63432088
29Influenza A_Homo sapiens_hsa051641.59290046
30Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.57189226
31Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.46616866
32Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.45928256
33Hematopoietic cell lineage_Homo sapiens_hsa046401.43657641
34Chemokine signaling pathway_Homo sapiens_hsa040621.39639476
35Toxoplasmosis_Homo sapiens_hsa051451.31129084
36Autoimmune thyroid disease_Homo sapiens_hsa053201.24886734
37PPAR signaling pathway_Homo sapiens_hsa033201.24188252
38Herpes simplex infection_Homo sapiens_hsa051681.23999841
39B cell receptor signaling pathway_Homo sapiens_hsa046621.23905005
40Galactose metabolism_Homo sapiens_hsa000521.19294715
41Apoptosis_Homo sapiens_hsa042101.19123784
42Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.16923954
43Other glycan degradation_Homo sapiens_hsa005111.15282638
44Pentose phosphate pathway_Homo sapiens_hsa000301.11372287
45Jak-STAT signaling pathway_Homo sapiens_hsa046301.10414174
46Viral myocarditis_Homo sapiens_hsa054161.05528981
47Fructose and mannose metabolism_Homo sapiens_hsa000511.04823887
48Amoebiasis_Homo sapiens_hsa051461.04610158
49AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.01129869
50Shigellosis_Homo sapiens_hsa051310.98037387
51Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.94378060
52Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.93223857
53Antigen processing and presentation_Homo sapiens_hsa046120.92935572
54Steroid biosynthesis_Homo sapiens_hsa001000.90429994
55Sulfur metabolism_Homo sapiens_hsa009200.90080139
56Complement and coagulation cascades_Homo sapiens_hsa046100.87086496
57Prion diseases_Homo sapiens_hsa050200.86240115
58Hepatitis B_Homo sapiens_hsa051610.79693320
59Primary immunodeficiency_Homo sapiens_hsa053400.74829438
60Leukocyte transendothelial migration_Homo sapiens_hsa046700.74414426
61Vibrio cholerae infection_Homo sapiens_hsa051100.74244510
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73837994
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72184955
64Hepatitis C_Homo sapiens_hsa051600.69647874
65Glycosaminoglycan degradation_Homo sapiens_hsa005310.64975922
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61902941
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61521706
68Bladder cancer_Homo sapiens_hsa052190.59548327
69T cell receptor signaling pathway_Homo sapiens_hsa046600.55562435
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53546686
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50873736
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46279908
73Platelet activation_Homo sapiens_hsa046110.45395726
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44860152
75Prolactin signaling pathway_Homo sapiens_hsa049170.44508905
76Acute myeloid leukemia_Homo sapiens_hsa052210.43837020
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.42899105
78Fatty acid elongation_Homo sapiens_hsa000620.41665742
79Notch signaling pathway_Homo sapiens_hsa043300.39159413
80Glutathione metabolism_Homo sapiens_hsa004800.38140266
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.37499290
82Mineral absorption_Homo sapiens_hsa049780.36601186
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.36309619
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.34265089
85HIF-1 signaling pathway_Homo sapiens_hsa040660.34077454
86Epstein-Barr virus infection_Homo sapiens_hsa051690.33720708
87Synaptic vesicle cycle_Homo sapiens_hsa047210.31267669
88Renin-angiotensin system_Homo sapiens_hsa046140.29135755
89Proteasome_Homo sapiens_hsa030500.28230513
90Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28168722
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.27368247
92Type II diabetes mellitus_Homo sapiens_hsa049300.27269248
93Renal cell carcinoma_Homo sapiens_hsa052110.25252635
94GnRH signaling pathway_Homo sapiens_hsa049120.23451218
95Carbon metabolism_Homo sapiens_hsa012000.22637589
96Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.21357973
97Proteoglycans in cancer_Homo sapiens_hsa052050.21107076
98Chronic myeloid leukemia_Homo sapiens_hsa052200.20481436
99Viral carcinogenesis_Homo sapiens_hsa052030.20274774
100Pancreatic cancer_Homo sapiens_hsa052120.20128621
101Ether lipid metabolism_Homo sapiens_hsa005650.19679798
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.19321828
103Sphingolipid metabolism_Homo sapiens_hsa006000.18962048
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.16839578
105Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.16498847
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.15793621
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.15775107
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.14883676
109Insulin resistance_Homo sapiens_hsa049310.14682414
110Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.13182191
111Dorso-ventral axis formation_Homo sapiens_hsa043200.12968309
112Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.11768906
113Carbohydrate digestion and absorption_Homo sapiens_hsa049730.10735324
114Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.08996264
115Endocytosis_Homo sapiens_hsa041440.07890951
116FoxO signaling pathway_Homo sapiens_hsa040680.06611215
117VEGF signaling pathway_Homo sapiens_hsa043700.05636438
118Histidine metabolism_Homo sapiens_hsa003400.04796361

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