DDA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.96617427
2DNA deamination (GO:0045006)4.91284322
3sequestering of actin monomers (GO:0042989)4.63654380
4negative regulation of DNA-templated transcription, elongation (GO:0032785)4.40902378
5GDP-mannose metabolic process (GO:0019673)4.22673975
6viral protein processing (GO:0019082)4.01570563
7proteasome assembly (GO:0043248)4.01474741
8negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)4.00123046
9virion assembly (GO:0019068)3.98551572
10negative regulation of microtubule polymerization (GO:0031115)3.89281688
11type B pancreatic cell proliferation (GO:0044342)3.75556892
12peptidyl-arginine omega-N-methylation (GO:0035247)3.75070879
13ribosomal small subunit assembly (GO:0000028)3.60670383
14negative regulation of protein oligomerization (GO:0032460)3.57881501
15nuclear envelope reassembly (GO:0031468)3.55619445
16mitotic nuclear envelope reassembly (GO:0007084)3.55619445
17protein retention in ER lumen (GO:0006621)3.50766903
18barbed-end actin filament capping (GO:0051016)3.49005935
19NIK/NF-kappaB signaling (GO:0038061)3.48329348
20negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.48141518
21regulation of translational termination (GO:0006449)3.47836326
22viral transcription (GO:0019083)3.47692216
23positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.46619956
24histone arginine methylation (GO:0034969)3.44909753
25lipopolysaccharide biosynthetic process (GO:0009103)3.43043324
26regulation of protein heterodimerization activity (GO:0043497)3.41846142
27translational termination (GO:0006415)3.31709963
28positive regulation of T cell apoptotic process (GO:0070234)3.29584264
29UV protection (GO:0009650)3.28381030
30anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.27760698
31maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.27632549
32negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.25943109
33negative regulation of ligase activity (GO:0051352)3.25943109
34regulation of nuclear cell cycle DNA replication (GO:0033262)3.25409660
35pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.18756293
36positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.18604040
37regulation of early endosome to late endosome transport (GO:2000641)3.17372293
38translational elongation (GO:0006414)3.17197670
39negative regulation of B cell apoptotic process (GO:0002903)3.16942989
40peptidyl-arginine N-methylation (GO:0035246)3.16191954
41peptidyl-arginine methylation (GO:0018216)3.16191954
42regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.14350891
43deoxyribose phosphate biosynthetic process (GO:0046385)3.13801756
442-deoxyribonucleotide biosynthetic process (GO:0009265)3.13801756
45purine deoxyribonucleotide catabolic process (GO:0009155)3.10486438
46purine deoxyribonucleotide metabolic process (GO:0009151)3.08263736
47regulation of regulatory T cell differentiation (GO:0045589)3.07018381
48cellular response to virus (GO:0098586)3.06853994
49modulation by virus of host process (GO:0019054)3.03172572
50deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.01891344
51protein localization to endosome (GO:0036010)3.00316283
52localization within membrane (GO:0051668)2.99386236
53negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.99354532
54positive regulation of gamma-delta T cell activation (GO:0046645)2.94392448
55translational initiation (GO:0006413)2.94305786
56regulation of apoptotic process involved in morphogenesis (GO:1902337)2.94288098
57regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.91292484
58SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.90441295
59cellular protein complex disassembly (GO:0043624)2.88078946
60positive regulation of lymphocyte apoptotic process (GO:0070230)2.86912555
61nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.86133435
62regulation of mammary gland epithelial cell proliferation (GO:0033599)2.86126204
63maturation of 5.8S rRNA (GO:0000460)2.84990978
64regulation of protein homooligomerization (GO:0032462)2.84129811
65protein complex localization (GO:0031503)2.83724049
66DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.81799807
67viral life cycle (GO:0019058)2.81361139
68protein targeting to ER (GO:0045047)2.80215388
69negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.80142668
70polyamine biosynthetic process (GO:0006596)2.79392865
71cotranslational protein targeting to membrane (GO:0006613)2.79379983
72protein insertion into membrane (GO:0051205)2.78150145
73positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.77407731
74purine nucleotide salvage (GO:0032261)2.76326381
75autophagic vacuole fusion (GO:0000046)2.73356657
76intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.73294234
77signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.73294234
78lipopolysaccharide metabolic process (GO:0008653)2.72813351
79endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.72780076
80DNA unwinding involved in DNA replication (GO:0006268)2.71838035
81tRNA methylation (GO:0030488)2.71512509
82protein complex disassembly (GO:0043241)2.71208314
83signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.70636830
84signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.70636830
85signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.70636830
86positive regulation of protein homooligomerization (GO:0032464)2.69481736
87deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.68170678
88mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.67777833
89protein deneddylation (GO:0000338)2.66835623
90regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.65486240
91protein targeting to mitochondrion (GO:0006626)2.65448511
92positive regulation of mitochondrion organization (GO:0010822)2.65281192
93signal transduction involved in DNA damage checkpoint (GO:0072422)2.65054687
94signal transduction involved in DNA integrity checkpoint (GO:0072401)2.65054687
95establishment of protein localization to endoplasmic reticulum (GO:0072599)2.64029057
96iron-sulfur cluster assembly (GO:0016226)2.63965791
97metallo-sulfur cluster assembly (GO:0031163)2.63965791
98pyrimidine nucleotide catabolic process (GO:0006244)2.63874909
99positive regulation of ligase activity (GO:0051351)2.63804629
100nucleobase-containing small molecule interconversion (GO:0015949)2.63774260
101pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.63758168
102macromolecular complex disassembly (GO:0032984)2.63646853
103regulation of defense response to virus by virus (GO:0050690)2.63333994
104ATP synthesis coupled proton transport (GO:0015986)2.63219606
105energy coupled proton transport, down electrochemical gradient (GO:0015985)2.63219606
106de novo protein folding (GO:0006458)2.63134518
107modulation by symbiont of host cellular process (GO:0044068)2.62860313
108regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.62223562
109positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.62223562
110signal transduction involved in cell cycle checkpoint (GO:0072395)2.61943571
111transcription elongation from RNA polymerase III promoter (GO:0006385)2.61909395
112termination of RNA polymerase III transcription (GO:0006386)2.61909395
113ribosomal small subunit biogenesis (GO:0042274)2.61897290
1142-deoxyribonucleotide metabolic process (GO:0009394)2.61806692
115regulation of centriole replication (GO:0046599)2.61796978
116regulation of mitochondrial membrane potential (GO:0051881)2.61768943
117regulation of RNA export from nucleus (GO:0046831)2.61752485
118positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.61662323
119mitochondrial calcium ion transport (GO:0006851)2.61343724
120nucleotide salvage (GO:0043173)2.61320990
121base-excision repair, AP site formation (GO:0006285)2.61178469
122positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.60393509
123protein localization to endoplasmic reticulum (GO:0070972)2.60228238
124positive regulation of release of cytochrome c from mitochondria (GO:0090200)2.59420463
125establishment of protein localization to mitochondrion (GO:0072655)2.59029267
126protein targeting to plasma membrane (GO:0072661)2.58682503
127de novo posttranslational protein folding (GO:0051084)2.58491150
128Arp2/3 complex-mediated actin nucleation (GO:0034314)2.57178064
129regulation of ubiquitin-protein transferase activity (GO:0051438)2.56536551
130formation of translation preinitiation complex (GO:0001731)2.56378160
131regulation of gamma-delta T cell differentiation (GO:0045586)2.55826509
132regulation of release of cytochrome c from mitochondria (GO:0090199)2.55363714
133deoxyribonucleotide catabolic process (GO:0009264)2.54827501
134regulation of cellular amino acid metabolic process (GO:0006521)2.54068974
135DNA replication checkpoint (GO:0000076)2.52777411
136regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.52005701
137ribosome biogenesis (GO:0042254)2.51926446
138pseudouridine synthesis (GO:0001522)2.51308380
139cellular copper ion homeostasis (GO:0006878)2.50772429
140antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.50321523
141deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.49117917
142maturation of SSU-rRNA (GO:0030490)2.48628384
143protein K11-linked ubiquitination (GO:0070979)2.48403396
144respiratory electron transport chain (GO:0022904)2.46899958
145regulation of ligase activity (GO:0051340)2.45971238
146establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.45568187
147mitochondrion transport along microtubule (GO:0047497)2.45568187
148negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.45298424
149chaperone-mediated protein transport (GO:0072321)2.45109117
150spliceosomal snRNP assembly (GO:0000387)2.44981872
151protein maturation by protein folding (GO:0022417)2.43928748
152chaperone mediated protein folding requiring cofactor (GO:0051085)2.43856666
153mitotic spindle assembly checkpoint (GO:0007094)2.43689565
154positive regulation of TOR signaling (GO:0032008)2.42312824
155negative regulation of cell size (GO:0045792)2.42032613
156activation of MAPKKK activity (GO:0000185)2.41926079
157electron transport chain (GO:0022900)2.41863885
158negative regulation of RNA splicing (GO:0033119)2.40842579
159regulation of metalloenzyme activity (GO:0048552)2.40780763
160positive regulation of cell cycle arrest (GO:0071158)2.40581467
161regulation of G0 to G1 transition (GO:0070316)2.39345629
162response to gravity (GO:0009629)2.39254736
163purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.39031518
164mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.38768880
165retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.38430114
166COPI coating of Golgi vesicle (GO:0048205)2.38304129
167Golgi transport vesicle coating (GO:0048200)2.38304129
168positive regulation of defense response to virus by host (GO:0002230)2.38251792
169regulation of mitochondrion organization (GO:0010821)2.38042536
170ribonucleoprotein complex biogenesis (GO:0022613)2.38001522
171cellular response to nicotine (GO:0071316)2.37141908
172guanosine-containing compound biosynthetic process (GO:1901070)2.36523280
173negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.35679156
174negative regulation of mitotic sister chromatid separation (GO:2000816)2.35222394
175negative regulation of mitotic sister chromatid segregation (GO:0033048)2.35222394
176negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.35222394
177negative regulation of sister chromatid segregation (GO:0033046)2.35222394
178deoxyribose phosphate metabolic process (GO:0019692)2.33394318
179deoxyribose phosphate catabolic process (GO:0046386)2.29745390

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.94781172
2MYC_18555785_ChIP-Seq_MESCs_Mouse3.26840430
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.95906515
4* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.72855254
5* ETS1_20019798_ChIP-Seq_JURKAT_Human2.60685339
6MYC_18358816_ChIP-ChIP_MESCs_Mouse2.55459974
7* XRN2_22483619_ChIP-Seq_HELA_Human2.41431836
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.40471976
9MYC_22102868_ChIP-Seq_BL_Human2.34459450
10* GABP_17652178_ChIP-ChIP_JURKAT_Human2.29482564
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.22628397
12TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.11843897
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.06734236
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.06378822
15SRY_22984422_ChIP-ChIP_TESTIS_Rat2.04002127
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.01917066
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.01784561
18CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.96829894
19TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.95079531
20VDR_21846776_ChIP-Seq_THP-1_Human1.90893142
21FOXM1_23109430_ChIP-Seq_U2OS_Human1.85904064
22DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.85243330
23GABP_19822575_ChIP-Seq_HepG2_Human1.84083186
24THAP11_20581084_ChIP-Seq_MESCs_Mouse1.83842737
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.83099809
26CIITA_25753668_ChIP-Seq_RAJI_Human1.82470867
27DCP1A_22483619_ChIP-Seq_HELA_Human1.77815932
28KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.76132490
29STAT6_21828071_ChIP-Seq_BEAS2B_Human1.75161720
30CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.72587830
31ELK3_25401928_ChIP-Seq_HUVEC_Human1.72125143
32NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71369580
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.70342657
34PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.68442497
35VDR_23849224_ChIP-Seq_CD4+_Human1.64099726
36FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.62595671
37KLF4_18555785_ChIP-Seq_MESCs_Mouse1.59926717
38TTF2_22483619_ChIP-Seq_HELA_Human1.58479553
39NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.57310879
40RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.56973561
41LXR_22292898_ChIP-Seq_THP-1_Human1.56954687
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.56702560
43ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56111607
44BCOR_27268052_Chip-Seq_Bcells_Human1.52930619
45* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.50054734
46ZNF263_19887448_ChIP-Seq_K562_Human1.49463841
47CTCF_27219007_Chip-Seq_ERYTHROID_Human1.48837570
48ZFP281_18757296_ChIP-ChIP_E14_Mouse1.48419807
49ELF1_20517297_ChIP-Seq_JURKAT_Human1.48160767
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.47592394
51HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.47059658
52YY1_21170310_ChIP-Seq_MESCs_Mouse1.45189537
53CTCF_18555785_ChIP-Seq_MESCs_Mouse1.43109086
54SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.42694244
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.40750799
56KDM2B_26808549_Chip-Seq_DND41_Human1.40305662
57SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.39947405
58TET1_21451524_ChIP-Seq_MESCs_Mouse1.36141578
59YY1_22570637_ChIP-Seq_MALME-3M_Human1.34204768
60HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.34100216
61MYCN_18555785_ChIP-Seq_MESCs_Mouse1.33265067
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.32707006
63KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.32280215
64FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.32159173
65MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.32118313
66CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.31387439
67SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.31015623
68MAF_26560356_Chip-Seq_TH1_Human1.30463313
69BCL6_27268052_Chip-Seq_Bcells_Human1.29844323
70FOXP3_21729870_ChIP-Seq_TREG_Human1.29808468
71SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.29090554
72E2F1_20622854_ChIP-Seq_HELA_Human1.27664657
73P68_20966046_ChIP-Seq_HELA_Human1.27475650
74ATF3_27146783_Chip-Seq_COLON_Human1.26177746
75VDR_24763502_ChIP-Seq_THP-1_Human1.25331696
76NANOG_18555785_ChIP-Seq_MESCs_Mouse1.23864820
77CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.23649634
78* MAF_26560356_Chip-Seq_TH2_Human1.23488694
79* CTCF_20526341_ChIP-Seq_ESCs_Human1.23365112
80POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.23222760
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.23181179
82* FOXP1_21924763_ChIP-Seq_HESCs_Human1.22750502
83UTX_26944678_Chip-Seq_JUKART_Human1.20998829
84ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.20360852
85SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.20323109
86CTCF_26484167_Chip-Seq_Bcells_Mouse1.19990459
87SMC4_20622854_ChIP-Seq_HELA_Human1.19939440
88CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.19650403
89UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.19517402
90E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.17845441
91ELK1_22589737_ChIP-Seq_MCF10A_Human1.17343822
92RARG_19884340_ChIP-ChIP_MEFs_Mouse1.17248080
93EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16426565
94TP53_22127205_ChIP-Seq_IMR90_Human1.16183625
95SA1_27219007_Chip-Seq_Bcells_Human1.15252653
96KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.14828204
97* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.14299901
98RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.14073468
99EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.13905070
100ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13371147
101E2F7_22180533_ChIP-Seq_HELA_Human1.13338644
102TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.13323138
103EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12690344
104TRIM28_21343339_ChIP-Seq_HEK293_Human1.11774226
105STAT4_19710469_ChIP-ChIP_TH1__Mouse1.10927699
106* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.10850705
107PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.10793444
108CTCF_27219007_Chip-Seq_Bcells_Human1.10778133
109DNAJC2_21179169_ChIP-ChIP_NT2_Human1.10601722
110MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.10483134
111MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.09739784
112RARA_24833708_ChIP-Seq_LIVER_Mouse1.09380799
113OCT4_18692474_ChIP-Seq_MEFs_Mouse1.09183735
114E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.09026803
115RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.08612307
116TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07887075
117DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06877989
118* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.06863846
119CTCF_21964334_Chip-Seq_Bcells_Human1.06759658
120PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06716622
121SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.06477053
122RARB_24833708_ChIP-Seq_LIVER_Mouse1.06426457
123TP63_19390658_ChIP-ChIP_HaCaT_Human1.06208860
124* TCF7_22412390_ChIP-Seq_EML_Mouse1.05645597
125SA1_27219007_Chip-Seq_ERYTHROID_Human1.05461241
126PU.1_20513432_ChIP-Seq_Bcells_Mouse1.04417222
127SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02237631
128SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01880174
129ELF1_17652178_ChIP-ChIP_JURKAT_Human1.01718718
130TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01600367
131PHF8_20622854_ChIP-Seq_HELA_Human1.01450197
132TP63_17297297_ChIP-ChIP_HaCaT_Human0.99917674
133FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.99403219
134RACK7_27058665_Chip-Seq_MCF-7_Human0.99398878
135ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.98741318
136TFEB_21752829_ChIP-Seq_HELA_Human0.98698548
137BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96983273

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002877_abnormal_melanocyte_morpholog3.46004753
2MP0003693_abnormal_embryo_hatching3.09504505
3MP0005451_abnormal_body_composition2.91457385
4MP0004858_abnormal_nervous_system2.79874469
5MP0005058_abnormal_lysosome_morphology2.72994104
6MP0009840_abnormal_foam_cell2.72458206
7MP0008932_abnormal_embryonic_tissue2.17530785
8MP0002653_abnormal_ependyma_morphology2.14917756
9MP0003111_abnormal_nucleus_morphology2.11654585
10MP0000013_abnormal_adipose_tissue2.07879759
11MP0005257_abnormal_intraocular_pressure2.06564510
12MP0001849_ear_inflammation2.06115917
13MP0004859_abnormal_synaptic_plasticity2.03791863
14MP0003077_abnormal_cell_cycle1.99613804
15MP0003191_abnormal_cellular_cholesterol1.94977889
16MP0004957_abnormal_blastocyst_morpholog1.94530706
17MP0009333_abnormal_splenocyte_physiolog1.93734043
18MP0008260_abnormal_autophagy1.80428954
19MP0010352_gastrointestinal_tract_polyps1.76864372
20MP0008007_abnormal_cellular_replicative1.75441339
21MP0000678_abnormal_parathyroid_gland1.74221060
22MP0001905_abnormal_dopamine_level1.73087514
23MP0010030_abnormal_orbit_morphology1.71186949
24MP0000490_abnormal_crypts_of1.71024293
25MP0000750_abnormal_muscle_regeneration1.67184017
26MP0004270_analgesia1.65071476
27MP0008961_abnormal_basal_metabolism1.64796498
28MP0002148_abnormal_hypersensitivity_rea1.64400620
29MP0001542_abnormal_bone_strength1.62703011
30MP0003279_aneurysm1.62044844
31MP0009785_altered_susceptibility_to1.61415330
32MP0005623_abnormal_meninges_morphology1.58639067
33MP0001730_embryonic_growth_arrest1.58290507
34MP0005000_abnormal_immune_tolerance1.56777639
35MP0003705_abnormal_hypodermis_morpholog1.56739554
36MP0000358_abnormal_cell_content/1.56222105
37MP0003329_amyloid_beta_deposits1.53547471
38MP0009278_abnormal_bone_marrow1.51107729
39MP0003303_peritoneal_inflammation1.48130569
40MP0004808_abnormal_hematopoietic_stem1.45914435
41MP0003763_abnormal_thymus_physiology1.45647763
42MP0002909_abnormal_adrenal_gland1.45557405
43MP0000685_abnormal_immune_system1.45324125
44MP0005083_abnormal_biliary_tract1.38011863
45MP0001533_abnormal_skeleton_physiology1.37730109
46MP0005671_abnormal_response_to1.36383519
47MP0005464_abnormal_platelet_physiology1.35092412
48MP0002163_abnormal_gland_morphology1.33500309
49MP0000350_abnormal_cell_proliferation1.32782803
50MP0002184_abnormal_innervation1.31284720
51MP0002751_abnormal_autonomic_nervous1.31096191
52MP0000703_abnormal_thymus_morphology1.30611162
53MP0002723_abnormal_immune_serum1.29883658
54MP0005025_abnormal_response_to1.29160818
55MP0001348_abnormal_lacrimal_gland1.28776958
56MP0006292_abnormal_olfactory_placode1.27679113
57MP0000343_altered_response_to1.27639946
58MP0004133_heterotaxia1.24818820
59MP0008438_abnormal_cutaneous_collagen1.23960254
60MP0008874_decreased_physiological_sensi1.23718271
61MP0000858_altered_metastatic_potential1.23483206
62MP0010386_abnormal_urinary_bladder1.22279244
63MP0000534_abnormal_ureter_morphology1.21502233
64MP0009379_abnormal_foot_pigmentation1.20720514
65MP0002080_prenatal_lethality1.20051542
66MP0005501_abnormal_skin_physiology1.18224899
67MP0002089_abnormal_postnatal_growth/wei1.17054803
68MP0005076_abnormal_cell_differentiation1.16784822
69MP0003942_abnormal_urinary_system1.16432072
70MP0008770_decreased_survivor_rate1.15412310
71MP0005423_abnormal_somatic_nervous1.15177737
72MP0001819_abnormal_immune_cell1.14844408
73MP0003866_abnormal_defecation1.14643679
74MP0002420_abnormal_adaptive_immunity1.14348698
75MP0001873_stomach_inflammation1.13695527
76MP0005390_skeleton_phenotype1.13471220
77MP0003183_abnormal_peptide_metabolism1.12677845
78MP0009053_abnormal_anal_canal1.11858876
79MP0004233_abnormal_muscle_weight1.11635944
80MP0001697_abnormal_embryo_size1.10816967
81MP0002452_abnormal_antigen_presenting1.09836393
82MP0006276_abnormal_autonomic_nervous1.09729396
83MP0004811_abnormal_neuron_physiology1.09401822
84MP0000604_amyloidosis1.05851008
85MP0003119_abnormal_digestive_system1.04750749
86MP0000465_gastrointestinal_hemorrhage1.04227843
87MP0005275_abnormal_skin_tensile1.04138872
88MP0000778_abnormal_nervous_system1.02802064
89MP0003861_abnormal_nervous_system1.02503079
90MP0001800_abnormal_humoral_immune1.01965049
91MP0002332_abnormal_exercise_endurance1.01936506
92MP0001968_abnormal_touch/_nociception1.01315139
93MP0002085_abnormal_embryonic_tissue1.01276657
94MP0003075_altered_response_to1.00850528
95MP0005375_adipose_tissue_phenotype0.99724555
96MP0002084_abnormal_developmental_patter0.98456806
97MP0005410_abnormal_fertilization0.98225560
98MP0002398_abnormal_bone_marrow0.97825391
99MP0009764_decreased_sensitivity_to0.96844266
100MP0003806_abnormal_nucleotide_metabolis0.96737922
101MP0005023_abnormal_wound_healing0.96646567
102MP0006082_CNS_inflammation0.96484004
103MP0010094_abnormal_chromosome_stability0.96400099
104MP0000313_abnormal_cell_death0.95212512
105MP0000716_abnormal_immune_system0.93144291
106MP0003786_premature_aging0.92952417
107MP0000681_abnormal_thyroid_gland0.92462195
108MP0003453_abnormal_keratinocyte_physiol0.90668611
109MP0005084_abnormal_gallbladder_morpholo0.90606428
110MP0002019_abnormal_tumor_incidence0.90504249
111MP0006036_abnormal_mitochondrial_physio0.89145188
112MP0001299_abnormal_eye_distance/0.88059830
113MP0010368_abnormal_lymphatic_system0.87681149
114MP0005397_hematopoietic_system_phenotyp0.87673851
115MP0001545_abnormal_hematopoietic_system0.87673851
116MP0002735_abnormal_chemical_nociception0.87227247
117MP0001790_abnormal_immune_system0.87013550
118MP0005387_immune_system_phenotype0.87013550
119MP0002419_abnormal_innate_immunity0.86666826
120MP0000759_abnormal_skeletal_muscle0.86455455
121MP0002933_joint_inflammation0.84847177
122MP0003186_abnormal_redox_activity0.83660938
123MP0005165_increased_susceptibility_to0.83053861
124MP0002405_respiratory_system_inflammati0.81842106
125MP0001529_abnormal_vocalization0.81511156
126MP0000733_abnormal_muscle_development0.80800741
127MP0002734_abnormal_mechanical_nocicepti0.80455453
128MP0004510_myositis0.80068707
129MP0005384_cellular_phenotype0.79745599
130MP0003566_abnormal_cell_adhesion0.79397593
131MP0008789_abnormal_olfactory_epithelium0.78735944
132MP0000955_abnormal_spinal_cord0.78642919
133MP0003879_abnormal_hair_cell0.78185250
134MP0003635_abnormal_synaptic_transmissio0.78064120
135MP0005670_abnormal_white_adipose0.77910502
136MP0002722_abnormal_immune_system0.77602829
137MP0002733_abnormal_thermal_nociception0.76923834
138MP0000751_myopathy0.76428648
139MP0001970_abnormal_pain_threshold0.75016950
140MP0001845_abnormal_inflammatory_respons0.74529282
141MP0005621_abnormal_cell_physiology0.73700335
142MP0008469_abnormal_protein_level0.73075922
143MP0001672_abnormal_embryogenesis/_devel0.72827116
144MP0005380_embryogenesis_phenotype0.72827116
145MP0004185_abnormal_adipocyte_glucose0.72697634
146MP0000537_abnormal_urethra_morphology0.72538671
147MP0005166_decreased_susceptibility_to0.72070990
148MP0005197_abnormal_uvea_morphology0.70768191
149MP0001853_heart_inflammation0.70464863
150MP0002736_abnormal_nociception_after0.70234480
151MP0009931_abnormal_skin_appearance0.70121922
152MP0001216_abnormal_epidermal_layer0.69981746
153MP0000003_abnormal_adipose_tissue0.69536287
154MP0003436_decreased_susceptibility_to0.69198474
155MP0004134_abnormal_chest_morphology0.68405859
156MP0008058_abnormal_DNA_repair0.68110364
157MP0003984_embryonic_growth_retardation0.67299756
158MP0002970_abnormal_white_adipose0.67294410
159MP0002429_abnormal_blood_cell0.66507714
160MP0005508_abnormal_skeleton_morphology0.65953114
161MP0003123_paternal_imprinting0.65706946
162MP0003959_abnormal_lean_body0.65636371
163MP0003448_altered_tumor_morphology0.65244610
164MP0000613_abnormal_salivary_gland0.64485744
165MP0004197_abnormal_fetal_growth/weight/0.64386877
166MP0004947_skin_inflammation0.64381928
167MP0002088_abnormal_embryonic_growth/wei0.64105522

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)3.45360057
2Vertebral compression fractures (HP:0002953)3.18993972
3Carpal bone hypoplasia (HP:0001498)3.11202871
4Distal lower limb amyotrophy (HP:0008944)3.00232318
5Testicular atrophy (HP:0000029)2.97019808
6Amyotrophic lateral sclerosis (HP:0007354)2.96991764
7Aplasia/Hypoplasia of the sacrum (HP:0008517)2.89036458
8Abnormality of the heme biosynthetic pathway (HP:0010472)2.79941120
9Delusions (HP:0000746)2.76983919
10Premature rupture of membranes (HP:0001788)2.76390801
11Rough bone trabeculation (HP:0100670)2.68215385
12Distal lower limb muscle weakness (HP:0009053)2.62270433
13Abnormality of the Achilles tendon (HP:0005109)2.60129098
14Trismus (HP:0000211)2.59822810
15Cerebral hypomyelination (HP:0006808)2.57103793
16Atrophy/Degeneration involving motor neurons (HP:0007373)2.54369561
17Hypercortisolism (HP:0001578)2.52898088
18Mutism (HP:0002300)2.51717196
19Abnormality of cells of the erythroid lineage (HP:0012130)2.48311766
20Large eyes (HP:0001090)2.46664366
21Patellar aplasia (HP:0006443)2.46156540
22Opisthotonus (HP:0002179)2.43139541
23Ragged-red muscle fibers (HP:0003200)2.42634194
24Microretrognathia (HP:0000308)2.42379762
25Progressive muscle weakness (HP:0003323)2.37865152
26Abnormality of the umbilical cord (HP:0010881)2.36451986
27Elevated erythrocyte sedimentation rate (HP:0003565)2.35545277
28Short nail (HP:0001799)2.34916342
29Aplasia/Hypoplasia of the patella (HP:0006498)2.34720965
30Abnormality of dentin (HP:0010299)2.34456122
31Poor head control (HP:0002421)2.32404673
32Dilatation of the ascending aorta (HP:0005111)2.29964864
33Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.28123326
34Deep palmar crease (HP:0006191)2.27310623
35Hyperparathyroidism (HP:0000843)2.26534225
36Breech presentation (HP:0001623)2.25446729
37Reduced subcutaneous adipose tissue (HP:0003758)2.25312041
38Pallor (HP:0000980)2.22519486
39Mitochondrial inheritance (HP:0001427)2.22336988
40Webbed neck (HP:0000465)2.21968322
41Spinal rigidity (HP:0003306)2.21894990
42Truncus arteriosus (HP:0001660)2.20063917
43Long palpebral fissure (HP:0000637)2.19563469
44Lower limb amyotrophy (HP:0007210)2.18406811
45Hand muscle atrophy (HP:0009130)2.17938233
46Wrist flexion contracture (HP:0001239)2.17530091
47Acute necrotizing encephalopathy (HP:0006965)2.17137944
48Upper limb muscle weakness (HP:0003484)2.16482147
49Congenital hip dislocation (HP:0001374)2.12787452
50Curly hair (HP:0002212)2.12516833
51Achilles tendon contracture (HP:0001771)2.12077344
52Abnormal number of erythroid precursors (HP:0012131)2.11068947
53Abnormal trabecular bone morphology (HP:0100671)2.09639488
54Genu recurvatum (HP:0002816)2.08936092
55Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.07175708
56Decreased activity of mitochondrial respiratory chain (HP:0008972)2.06004917
57Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.06004917
58Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.04937598
59Spinal cord compression (HP:0002176)2.03779066
60Calcaneovalgus deformity (HP:0001848)2.02257788
61Supranuclear gaze palsy (HP:0000605)2.01577101
62Abnormality of the fetal cardiovascular system (HP:0010948)2.00986537
63Abnormal umbilical cord blood vessels (HP:0011403)2.00986537
64Single umbilical artery (HP:0001195)2.00986537
65Shallow orbits (HP:0000586)2.00971612
66Petechiae (HP:0000967)2.00281043
67Diminished motivation (HP:0000745)1.99690615
68Flat capital femoral epiphysis (HP:0003370)1.99626630
69Adducted thumb (HP:0001181)1.99370827
70Hyperacusis (HP:0010780)1.98923614
71Nail dystrophy (HP:0008404)1.98851741
72Generalized amyotrophy (HP:0003700)1.98613461
73Reticulocytopenia (HP:0001896)1.98167180
74Cholecystitis (HP:0001082)1.97849174
75Abnormal gallbladder physiology (HP:0012438)1.97849174
76Hepatic necrosis (HP:0002605)1.97661916
77Abnormality of the acetabulum (HP:0003170)1.97545600
78Selective tooth agenesis (HP:0001592)1.96292943
79Stridor (HP:0010307)1.95552176
80Distal upper limb amyotrophy (HP:0007149)1.94811363
81Upper limb amyotrophy (HP:0009129)1.94811363
82Concave nail (HP:0001598)1.94530595
83Elbow flexion contracture (HP:0002987)1.94510115
84Emotional lability (HP:0000712)1.91870159
85Nonimmune hydrops fetalis (HP:0001790)1.90514874
86Aplasia/Hypoplasia of the brainstem (HP:0007362)1.89435487
87Hypoplasia of the brainstem (HP:0002365)1.89435487
88Breast hypoplasia (HP:0003187)1.88575083
89Broad distal phalanx of finger (HP:0009836)1.88043758
90Insomnia (HP:0100785)1.87568147
91Thoracolumbar scoliosis (HP:0002944)1.86617559
92Cerebral aneurysm (HP:0004944)1.86357032
93Apathy (HP:0000741)1.86201730
94Abnormal mitochondria in muscle tissue (HP:0008316)1.85604999
95Premature skin wrinkling (HP:0100678)1.84453276
96Interstitial pulmonary disease (HP:0006530)1.84418721
97Unilateral renal agenesis (HP:0000122)1.84282997
98Deformed tarsal bones (HP:0008119)1.83681706
99Bowed forearm bones (HP:0003956)1.83609768
100Bowing of the arm (HP:0006488)1.83609768
101Slender long bone (HP:0003100)1.83575324
102Axonal loss (HP:0003447)1.83473157
103Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.80971097
104Lissencephaly (HP:0001339)1.80957901
105Aplastic anemia (HP:0001915)1.80697631
106Entropion (HP:0000621)1.79872229
107Hypokinesia (HP:0002375)1.79847504
108Ulnar bowing (HP:0003031)1.79057536
109Anterior segment dysgenesis (HP:0007700)1.78931328
110Increased serum ferritin (HP:0003281)1.78930835
111Hepatocellular necrosis (HP:0001404)1.78453433
112Increased muscle lipid content (HP:0009058)1.77575183
113Atrophic scars (HP:0001075)1.76468483
114Seborrheic dermatitis (HP:0001051)1.76335745
115Myopathic facies (HP:0002058)1.76087330
116Myokymia (HP:0002411)1.75737425
117Increased intramyocellular lipid droplets (HP:0012240)1.75169142
118Progressive microcephaly (HP:0000253)1.74787118
119J-shaped sella turcica (HP:0002680)1.74459747
120Colon cancer (HP:0003003)1.73962837
121Centrally nucleated skeletal muscle fibers (HP:0003687)1.73612743
122Personality changes (HP:0000751)1.73424594
123Difficulty climbing stairs (HP:0003551)1.73361432
124Hypertensive crisis (HP:0100735)1.72795244
125Neoplasm of head and neck (HP:0012288)1.72786237
126Esophageal neoplasm (HP:0100751)1.72786237
127Complete atrioventricular canal defect (HP:0001674)1.72737528
128Joint stiffness (HP:0001387)1.70979541
129Soft skin (HP:0000977)1.69947079
130Hyperthyroidism (HP:0000836)1.69744439
131Neuroendocrine neoplasm (HP:0100634)1.69061916
132Abnormality of the nasal mucosa (HP:0000433)1.68924869
133Microvesicular hepatic steatosis (HP:0001414)1.68260223
134Distal arthrogryposis (HP:0005684)1.68216999
135Retinal dysplasia (HP:0007973)1.68153366
136Increased connective tissue (HP:0009025)1.68018799
137Abnormality of the distal phalanges of the toes (HP:0010182)1.67396774
138Broad face (HP:0000283)1.67247603
139Increased CSF lactate (HP:0002490)1.66125273
140Disproportionate tall stature (HP:0001519)1.65976163
141Fragile skin (HP:0001030)1.65917723
142Fragile nails (HP:0001808)1.65838171
143Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.65803581
144Gastrointestinal dysmotility (HP:0002579)1.65792936
145Diastasis recti (HP:0001540)1.65717411
146Overlapping toe (HP:0001845)1.64260746
147Peritonitis (HP:0002586)1.64230055
148Impaired platelet aggregation (HP:0003540)1.64177201
149Abnormal platelet function (HP:0011869)1.64177201
150Postnatal microcephaly (HP:0005484)1.64036456
151Bladder diverticulum (HP:0000015)1.63846393
152Abnormality of liposaccharide metabolism (HP:0010968)1.63515028
153Abnormality of glycosphingolipid metabolism (HP:0004343)1.63515028
154Abnormality of glycolipid metabolism (HP:0010969)1.63515028
155Fatigue (HP:0012378)1.62881431
156Abnormality of T cell physiology (HP:0011840)1.62791034
157Short clavicles (HP:0000894)1.61374055
158Renal Fanconi syndrome (HP:0001994)1.61285920
159Biconcave vertebral bodies (HP:0004586)1.59978694
160Abnormality of the anterior horn cell (HP:0006802)1.59648468
161Degeneration of anterior horn cells (HP:0002398)1.59648468
162Increased variability in muscle fiber diameter (HP:0003557)1.59225753
163Muscle fiber atrophy (HP:0100295)1.58815976
164Hydroureter (HP:0000072)1.57611465
165High anterior hairline (HP:0009890)1.57343219

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TESK24.36501837
2TESK13.86606022
3PLK43.57376299
4NME23.42583036
5BUB13.35341102
6ICK3.31251988
7LIMK13.11071922
8IRAK32.87424831
9MAPKAPK32.69442150
10VRK22.51532546
11MARK12.41497526
12EEF2K2.35867654
13LATS22.33790257
14SMG12.09767984
15TIE12.04799710
16PIM22.00356923
17FGFR41.89870939
18SIK11.88682398
19DYRK21.88435114
20SIK21.87467214
21SCYL21.84112461
22ERN11.82698323
23KDR1.81413805
24MAP3K91.81135474
25BCKDK1.70164822
26MAP3K111.59983944
27ARAF1.58832526
28TYRO31.57974143
29TAOK11.52284301
30TRIB31.50294375
31STK161.43044853
32TGFBR11.40319080
33PRPF4B1.39291593
34KSR21.38457421
35MAP4K11.37607101
36NTRK21.32499636
37PDGFRA1.29399283
38LRRK21.26947719
39SIK31.22543243
40TLK11.20681471
41BRAF1.20508683
42FGFR21.19730277
43MINK11.17549558
44AURKA1.17342702
45DAPK11.17334365
46LMTK21.15181279
47NME11.10061764
48EPHB11.10046297
49PRKD21.02555810
50MAP3K31.00660543
51RPS6KB20.95424651
52CDK140.95395819
53STK100.93981427
54DYRK30.93308646
55CDK120.89353332
56MAP3K100.88283036
57NEK20.87949263
58EPHA20.86855045
59MAP2K30.86747844
60IKBKB0.83277990
61RET0.83131244
62DAPK30.82831628
63MAPK110.81930730
64CDK11A0.79807286
65MAP3K80.79677432
66KSR10.79556131
67CDK150.79309893
68CDK180.79138150
69CSNK1G30.76883013
70BRSK10.75059067
71RAF10.74899408
72MAP3K120.74365812
73PAK10.73531595
74IRAK40.73494239
75SRPK10.73005574
76ILK0.72739650
77PRKD30.71800912
78GRK50.70892645
79ITK0.70740734
80STK380.66652536
81MAPK130.65827073
82MOS0.64586576
83MAP3K10.64368585
84MYLK0.63938955
85UHMK10.63703785
86BLK0.62292020
87TAOK20.61373777
88MAP2K20.59709379
89RPS6KA20.59272899
90PLK10.58138705
91GRK60.57741605
92RPS6KA40.57543167
93CDK80.56909945
94IRAK20.55802601
95TBK10.55397214
96PRKG20.55235931
97EIF2AK10.54898708
98TGFBR20.54445179
99PAK60.53836959
100EPHB20.53169808
101TXK0.52919636
102ZAP700.52798430
103HIPK20.52760258
104TTN0.52570630
105MST1R0.51295683
106PRKCI0.49700807
107PTK20.49390626
108CDK70.49362571
109BMX0.49100262
110NEK10.48782845
111WEE10.48649158
112RIPK10.48610890
113PLK20.48284307
114CLK10.47373957
115CHEK20.47233404
116PTK2B0.47107885
117ABL20.46393026
118PKN20.44490409
119NTRK10.44467733
120PAK30.43825521
121PDPK10.43520701
122DYRK1B0.43425149
123MTOR0.43241869
124CSNK1A1L0.42395653
125RPS6KA50.40896475
126FGFR10.39232023
127ALK0.38303330
128CAMK2G0.37461617
129CAMKK10.37415022
130CHUK0.36907048
131RPS6KC10.36431105
132RPS6KL10.36431105
133PAK40.34655572
134CSNK1G20.34240079
135RPS6KA60.34181404
136CDK190.33997088
137PTK60.33951328
138PAK20.33276486
139MAP2K70.32407261
140IRAK10.31812485
141ACVR1B0.31104965
142MARK20.29265002
143ZAK0.29006175
144AKT20.27483505
145DDR20.26624300
146PHKG20.25291645
147PHKG10.25291645
148HCK0.25241145
149MAPKAPK20.24063725
150PASK0.22848922

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.01608075
2Ribosome_Homo sapiens_hsa030102.79500696
3RNA polymerase_Homo sapiens_hsa030202.16430493
4DNA replication_Homo sapiens_hsa030302.00232166
5Spliceosome_Homo sapiens_hsa030401.96388273
6Base excision repair_Homo sapiens_hsa034101.94558109
7Alzheimers disease_Homo sapiens_hsa050101.74472489
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.66806870
9RNA transport_Homo sapiens_hsa030131.56266465
10SNARE interactions in vesicular transport_Homo sapiens_hsa041301.53613002
11Shigellosis_Homo sapiens_hsa051311.50506336
12Cell cycle_Homo sapiens_hsa041101.50179262
13Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.45771564
14Pyrimidine metabolism_Homo sapiens_hsa002401.43795286
15Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.39589118
16p53 signaling pathway_Homo sapiens_hsa041151.35292011
17Mismatch repair_Homo sapiens_hsa034301.34352060
18Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.29364802
19Glycosaminoglycan degradation_Homo sapiens_hsa005311.28316991
20VEGF signaling pathway_Homo sapiens_hsa043701.27540805
21Bladder cancer_Homo sapiens_hsa052191.24149975
22Other glycan degradation_Homo sapiens_hsa005111.23596144
23Epstein-Barr virus infection_Homo sapiens_hsa051691.22509214
24Neurotrophin signaling pathway_Homo sapiens_hsa047221.22038672
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.22018118
26Collecting duct acid secretion_Homo sapiens_hsa049661.18643493
27Nucleotide excision repair_Homo sapiens_hsa034201.13161312
28Colorectal cancer_Homo sapiens_hsa052101.13127589
29RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.12758348
30Chronic myeloid leukemia_Homo sapiens_hsa052201.12641115
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.11326979
32Synaptic vesicle cycle_Homo sapiens_hsa047211.07977411
33Glioma_Homo sapiens_hsa052141.07620170
34Acute myeloid leukemia_Homo sapiens_hsa052211.06041557
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05912224
36Endometrial cancer_Homo sapiens_hsa052131.05638249
37Apoptosis_Homo sapiens_hsa042101.04598191
38Oocyte meiosis_Homo sapiens_hsa041141.03019823
39Basal transcription factors_Homo sapiens_hsa030221.02919802
40Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.02656529
41Lysosome_Homo sapiens_hsa041421.01016333
42Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.00599510
43Vibrio cholerae infection_Homo sapiens_hsa051101.00438532
44Non-small cell lung cancer_Homo sapiens_hsa052230.97825909
45Thyroid cancer_Homo sapiens_hsa052160.96414986
46TNF signaling pathway_Homo sapiens_hsa046680.93282507
47T cell receptor signaling pathway_Homo sapiens_hsa046600.91859207
48ErbB signaling pathway_Homo sapiens_hsa040120.90933835
49Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.90247165
50Biosynthesis of amino acids_Homo sapiens_hsa012300.90080842
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90076925
52HTLV-I infection_Homo sapiens_hsa051660.90045015
53Fructose and mannose metabolism_Homo sapiens_hsa000510.89972572
54Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.89888177
55MicroRNAs in cancer_Homo sapiens_hsa052060.89546428
562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.87835832
57Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.87579182
58Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87102712
59Viral myocarditis_Homo sapiens_hsa054160.86426185
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86241934
61Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.86004556
62Viral carcinogenesis_Homo sapiens_hsa052030.85756386
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.85630853
64Toll-like receptor signaling pathway_Homo sapiens_hsa046200.85612071
65Folate biosynthesis_Homo sapiens_hsa007900.85160621
66Rheumatoid arthritis_Homo sapiens_hsa053230.84130276
67Gap junction_Homo sapiens_hsa045400.83965523
68N-Glycan biosynthesis_Homo sapiens_hsa005100.83003627
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82597284
70Alcoholism_Homo sapiens_hsa050340.82339967
71Galactose metabolism_Homo sapiens_hsa000520.82154963
72mRNA surveillance pathway_Homo sapiens_hsa030150.81944427
73Sulfur relay system_Homo sapiens_hsa041220.80644064
74Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79734719
75Renal cell carcinoma_Homo sapiens_hsa052110.76799858
76Sulfur metabolism_Homo sapiens_hsa009200.76690652
77Pentose phosphate pathway_Homo sapiens_hsa000300.75560333
78Parkinsons disease_Homo sapiens_hsa050120.75239729
79Pancreatic cancer_Homo sapiens_hsa052120.74586689
80Hippo signaling pathway_Homo sapiens_hsa043900.73823142
81Hepatitis B_Homo sapiens_hsa051610.71836914
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.71465566
83Endocytosis_Homo sapiens_hsa041440.68065576
84Salmonella infection_Homo sapiens_hsa051320.67978547
85Fatty acid elongation_Homo sapiens_hsa000620.67506410
86RNA degradation_Homo sapiens_hsa030180.67411450
87Huntingtons disease_Homo sapiens_hsa050160.66894943
88Cocaine addiction_Homo sapiens_hsa050300.66369170
89Regulation of autophagy_Homo sapiens_hsa041400.65414309
90Cardiac muscle contraction_Homo sapiens_hsa042600.64977271
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64887686
92Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.64214402
93Prolactin signaling pathway_Homo sapiens_hsa049170.64118782
94Osteoclast differentiation_Homo sapiens_hsa043800.63872824
95Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.63780366
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.63533878
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.62701122
98Insulin signaling pathway_Homo sapiens_hsa049100.61729776
99GnRH signaling pathway_Homo sapiens_hsa049120.61715416
100AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61029016
101Purine metabolism_Homo sapiens_hsa002300.60674249
102Prion diseases_Homo sapiens_hsa050200.60337361
103Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.59972907
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.57663385
105Antigen processing and presentation_Homo sapiens_hsa046120.55855578
106Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.55698512
107NF-kappa B signaling pathway_Homo sapiens_hsa040640.55121700
108Primary immunodeficiency_Homo sapiens_hsa053400.54250304
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53534381
110Pathways in cancer_Homo sapiens_hsa052000.53477594
111Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.53183418
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52819140
113Choline metabolism in cancer_Homo sapiens_hsa052310.52463447
114Small cell lung cancer_Homo sapiens_hsa052220.52262740
115B cell receptor signaling pathway_Homo sapiens_hsa046620.52108972
116HIF-1 signaling pathway_Homo sapiens_hsa040660.50531161
117Axon guidance_Homo sapiens_hsa043600.50465924
118Proteoglycans in cancer_Homo sapiens_hsa052050.50118763
119Rap1 signaling pathway_Homo sapiens_hsa040150.48965812
120Measles_Homo sapiens_hsa051620.48419891
121Homologous recombination_Homo sapiens_hsa034400.48367880
122Oxidative phosphorylation_Homo sapiens_hsa001900.48233496
123Notch signaling pathway_Homo sapiens_hsa043300.48017563
124Protein export_Homo sapiens_hsa030600.46894514
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.46716145
126Hematopoietic cell lineage_Homo sapiens_hsa046400.45827645
127Sphingolipid signaling pathway_Homo sapiens_hsa040710.45609023
128Cholinergic synapse_Homo sapiens_hsa047250.45333561
129mTOR signaling pathway_Homo sapiens_hsa041500.44021557
130Phagosome_Homo sapiens_hsa041450.43924041
131Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43540732
132Hedgehog signaling pathway_Homo sapiens_hsa043400.43038836
133Phenylalanine metabolism_Homo sapiens_hsa003600.43030474
134Hepatitis C_Homo sapiens_hsa051600.40205088
135Herpes simplex infection_Homo sapiens_hsa051680.36699785
136Morphine addiction_Homo sapiens_hsa050320.36443501
137MAPK signaling pathway_Homo sapiens_hsa040100.36427176
138Toxoplasmosis_Homo sapiens_hsa051450.33739713
139Malaria_Homo sapiens_hsa051440.32712289
140Intestinal immune network for IgA production_Homo sapiens_hsa046720.32614037
141Focal adhesion_Homo sapiens_hsa045100.31730788
142Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.30741722
143Graft-versus-host disease_Homo sapiens_hsa053320.30482018

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