Rank | Gene Set | Z-score |
---|---|---|
1 | phenol-containing compound catabolic process (GO:0019336) | 9.98368050 |
2 | * dopamine biosynthetic process (GO:0042416) | 9.30393590 |
3 | catecholamine transport (GO:0051937) | 8.21834109 |
4 | * catecholamine biosynthetic process (GO:0042423) | 6.90175408 |
5 | * catechol-containing compound biosynthetic process (GO:0009713) | 6.90175408 |
6 | angiotensin maturation (GO:0002003) | 6.66990645 |
7 | monoamine transport (GO:0015844) | 6.65911434 |
8 | epoxygenase P450 pathway (GO:0019373) | 6.23712779 |
9 | regulation of catecholamine metabolic process (GO:0042069) | 5.96326359 |
10 | regulation of dopamine metabolic process (GO:0042053) | 5.96326359 |
11 | * alkaloid metabolic process (GO:0009820) | 5.73804580 |
12 | neurotransmitter biosynthetic process (GO:0042136) | 5.71984933 |
13 | glucuronate metabolic process (GO:0019585) | 5.67722396 |
14 | uronic acid metabolic process (GO:0006063) | 5.67722396 |
15 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 5.65325504 |
16 | * dopamine metabolic process (GO:0042417) | 5.55661859 |
17 | cellular glucuronidation (GO:0052695) | 5.49275198 |
18 | regulation of bile acid biosynthetic process (GO:0070857) | 5.44521399 |
19 | neurotransmitter catabolic process (GO:0042135) | 5.36737472 |
20 | urea metabolic process (GO:0019627) | 4.88294087 |
21 | drug metabolic process (GO:0017144) | 4.86997624 |
22 | mating behavior (GO:0007617) | 4.82322094 |
23 | intestinal absorption (GO:0050892) | 4.81905280 |
24 | tyrosine metabolic process (GO:0006570) | 4.76325296 |
25 | urea cycle (GO:0000050) | 4.76256197 |
26 | neurotransmitter metabolic process (GO:0042133) | 4.73154548 |
27 | * phenol-containing compound biosynthetic process (GO:0046189) | 4.67109704 |
28 | drug catabolic process (GO:0042737) | 4.63967586 |
29 | behavioral response to nicotine (GO:0035095) | 4.59847097 |
30 | exogenous drug catabolic process (GO:0042738) | 4.53026083 |
31 | fat-soluble vitamin biosynthetic process (GO:0042362) | 4.38134432 |
32 | regulation of guanylate cyclase activity (GO:0031282) | 4.37914864 |
33 | very-low-density lipoprotein particle assembly (GO:0034379) | 4.33485276 |
34 | negative regulation of neurotransmitter transport (GO:0051589) | 4.32517620 |
35 | nitrogen cycle metabolic process (GO:0071941) | 4.25433469 |
36 | * toxin metabolic process (GO:0009404) | 4.24887556 |
37 | hormone catabolic process (GO:0042447) | 4.22804772 |
38 | cellular response to nicotine (GO:0071316) | 4.20435871 |
39 | synaptic transmission, dopaminergic (GO:0001963) | 4.20227837 |
40 | norepinephrine metabolic process (GO:0042415) | 4.19351868 |
41 | regulation of triglyceride catabolic process (GO:0010896) | 4.13578276 |
42 | bile acid metabolic process (GO:0008206) | 4.11054920 |
43 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 4.07988150 |
44 | NADH metabolic process (GO:0006734) | 4.07696723 |
45 | lipoprotein transport (GO:0042953) | 4.07002817 |
46 | nucleobase catabolic process (GO:0046113) | 4.05652771 |
47 | neuron cell-cell adhesion (GO:0007158) | 4.00817931 |
48 | fructose metabolic process (GO:0006000) | 3.99326228 |
49 | * catecholamine metabolic process (GO:0006584) | 3.98782879 |
50 | * catechol-containing compound metabolic process (GO:0009712) | 3.98782879 |
51 | flavonoid metabolic process (GO:0009812) | 3.96551594 |
52 | response to cocaine (GO:0042220) | 3.95146577 |
53 | prepulse inhibition (GO:0060134) | 3.84623835 |
54 | synaptic transmission, cholinergic (GO:0007271) | 3.84414760 |
55 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.83230086 |
56 | plasma lipoprotein particle assembly (GO:0034377) | 3.82018573 |
57 | glyoxylate metabolic process (GO:0046487) | 3.81511767 |
58 | regulation of oxidative phosphorylation (GO:0002082) | 3.79363801 |
59 | neurotransmitter uptake (GO:0001504) | 3.78999825 |
60 | response to corticosterone (GO:0051412) | 3.75202945 |
61 | regulation of neurotransmitter levels (GO:0001505) | 3.73789833 |
62 | arginine metabolic process (GO:0006525) | 3.70423412 |
63 | synaptic vesicle exocytosis (GO:0016079) | 3.69216377 |
64 | regulation of cholesterol esterification (GO:0010872) | 3.65863683 |
65 | regulation of cell-cell adhesion mediated by cadherin (GO:2000047) | 3.65564734 |
66 | neurotransmitter transport (GO:0006836) | 3.59857650 |
67 | omega-hydroxylase P450 pathway (GO:0097267) | 3.59661743 |
68 | diacylglycerol metabolic process (GO:0046339) | 3.58370851 |
69 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.58255733 |
70 | negative regulation of sterol transport (GO:0032372) | 3.57934860 |
71 | negative regulation of cholesterol transport (GO:0032375) | 3.57934860 |
72 | behavioral response to cocaine (GO:0048148) | 3.56546813 |
73 | insulin secretion (GO:0030073) | 3.54244043 |
74 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 3.53339049 |
75 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 3.53339049 |
76 | endocrine process (GO:0050886) | 3.53339049 |
77 | vitamin biosynthetic process (GO:0009110) | 3.48956220 |
78 | drug transmembrane transport (GO:0006855) | 3.48746053 |
79 | phospholipid efflux (GO:0033700) | 3.47973072 |
80 | digestion (GO:0007586) | 3.47721987 |
81 | high-density lipoprotein particle remodeling (GO:0034375) | 3.46838728 |
82 | dopaminergic neuron differentiation (GO:0071542) | 3.45682686 |
83 | plasma lipoprotein particle remodeling (GO:0034369) | 3.45147488 |
84 | protein-lipid complex remodeling (GO:0034368) | 3.45147488 |
85 | macromolecular complex remodeling (GO:0034367) | 3.45147488 |
86 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.43515207 |
87 | phenylpropanoid metabolic process (GO:0009698) | 3.43149201 |
88 | L-phenylalanine catabolic process (GO:0006559) | 3.41252619 |
89 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.41252619 |
90 | positive regulation of guanylate cyclase activity (GO:0031284) | 3.40711117 |
91 | ethanol oxidation (GO:0006069) | 3.34360946 |
92 | response to amphetamine (GO:0001975) | 3.33998072 |
93 | glutamate secretion (GO:0014047) | 3.31692189 |
94 | regulation of dopamine secretion (GO:0014059) | 3.30232546 |
95 | response to nicotine (GO:0035094) | 3.29828060 |
96 | response to water (GO:0009415) | 3.28771604 |
97 | neurotransmitter secretion (GO:0007269) | 3.27565740 |
98 | regulation of systemic arterial blood pressure (GO:0003073) | 3.25576658 |
99 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 3.25253467 |
100 | behavioral response to ethanol (GO:0048149) | 3.25193705 |
101 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.24294235 |
102 | L-phenylalanine metabolic process (GO:0006558) | 3.24294235 |
103 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.23205735 |
104 | * response to insecticide (GO:0017085) | 3.22162580 |
105 | aromatic amino acid family metabolic process (GO:0009072) | 3.20184655 |
106 | drug transport (GO:0015893) | 3.19663747 |
107 | bile acid biosynthetic process (GO:0006699) | 3.19579110 |
108 | protein-lipid complex assembly (GO:0065005) | 3.19186771 |
109 | positive regulation of lipid catabolic process (GO:0050996) | 3.19020872 |
110 | drinking behavior (GO:0042756) | 3.18086795 |
111 | cerebellar Purkinje cell layer development (GO:0021680) | 3.17191739 |
112 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 3.16449625 |
113 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 3.16449625 |
114 | glycoside metabolic process (GO:0016137) | 3.13036718 |
115 | acylglycerol homeostasis (GO:0055090) | 3.10119077 |
116 | triglyceride homeostasis (GO:0070328) | 3.10119077 |
117 | negative regulation of microtubule polymerization (GO:0031115) | 3.09631633 |
118 | response to mineralocorticoid (GO:0051385) | 3.08246755 |
119 | response to histamine (GO:0034776) | 3.07311244 |
120 | reverse cholesterol transport (GO:0043691) | 3.06442567 |
121 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.06057474 |
122 | protein maturation by protein folding (GO:0022417) | 3.05944804 |
123 | peptide hormone processing (GO:0016486) | 3.00082781 |
124 | cholesterol homeostasis (GO:0042632) | 2.99396923 |
125 | cholesterol efflux (GO:0033344) | 2.98964451 |
126 | regulation of cGMP biosynthetic process (GO:0030826) | 2.98017832 |
127 | plasma lipoprotein particle organization (GO:0071827) | 2.97487819 |
128 | intestinal cholesterol absorption (GO:0030299) | 2.96966920 |
129 | neuromuscular process controlling posture (GO:0050884) | 2.96477072 |
130 | renal system process involved in regulation of blood volume (GO:0001977) | 2.95649450 |
131 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.94947525 |
132 | vitamin transmembrane transport (GO:0035461) | 2.94554152 |
133 | heme transport (GO:0015886) | 2.94506128 |
134 | sterol homeostasis (GO:0055092) | 2.93082553 |
135 | bile acid and bile salt transport (GO:0015721) | 2.90727467 |
136 | negative regulation of catecholamine secretion (GO:0033604) | 2.86984801 |
137 | endocrine pancreas development (GO:0031018) | 2.86671417 |
138 | coenzyme catabolic process (GO:0009109) | 2.85886684 |
139 | vitamin A metabolic process (GO:0006776) | 2.84810062 |
140 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.84739000 |
141 | low-density lipoprotein particle remodeling (GO:0034374) | 2.84277833 |
142 | fat-soluble vitamin metabolic process (GO:0006775) | 2.83066800 |
143 | ethanol metabolic process (GO:0006067) | 2.83003138 |
144 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 2.81988742 |
145 | sulfate transmembrane transport (GO:1902358) | 2.80524625 |
146 | maintenance of gastrointestinal epithelium (GO:0030277) | 2.80520027 |
147 | lipoprotein metabolic process (GO:0042157) | 2.79583418 |
148 | homocysteine metabolic process (GO:0050667) | 2.79326795 |
149 | vitamin D metabolic process (GO:0042359) | 2.79051282 |
150 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.78642752 |
151 | L-ascorbic acid metabolic process (GO:0019852) | 2.77913583 |
152 | regulation of protein activation cascade (GO:2000257) | 2.77504962 |
153 | vitamin transport (GO:0051180) | 2.77042408 |
154 | primary alcohol catabolic process (GO:0034310) | 2.75303800 |
155 | regulation of vesicle fusion (GO:0031338) | 2.75044145 |
156 | response to amine (GO:0014075) | 2.73825087 |
157 | response to iron ion (GO:0010039) | 2.70824670 |
158 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.70088427 |
159 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.70088427 |
160 | COPI coating of Golgi vesicle (GO:0048205) | 2.67643888 |
161 | Golgi transport vesicle coating (GO:0048200) | 2.67643888 |
162 | peptide hormone secretion (GO:0030072) | 2.64794950 |
163 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.63318540 |
164 | * establishment of synaptic vesicle localization (GO:0097480) | 2.62380081 |
165 | * synaptic vesicle transport (GO:0048489) | 2.62380081 |
166 | ATP synthesis coupled proton transport (GO:0015986) | 2.59176618 |
167 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.59176618 |
168 | brain morphogenesis (GO:0048854) | 2.58633076 |
169 | neuron maturation (GO:0042551) | 2.57374398 |
170 | peptide secretion (GO:0002790) | 2.56063289 |
171 | detection of calcium ion (GO:0005513) | 2.55361618 |
172 | proline transport (GO:0015824) | 2.53569049 |
173 | enteric nervous system development (GO:0048484) | 2.53485085 |
174 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.53361569 |
175 | thalamus development (GO:0021794) | 2.52117052 |
176 | electron transport chain (GO:0022900) | 2.50894523 |
177 | intraspecies interaction between organisms (GO:0051703) | 2.49711102 |
178 | social behavior (GO:0035176) | 2.49711102 |
179 | * primary amino compound metabolic process (GO:1901160) | 2.49111576 |
180 | lactate metabolic process (GO:0006089) | 2.47060147 |
181 | respiratory electron transport chain (GO:0022904) | 2.46379750 |
182 | negative regulation of amine transport (GO:0051953) | 2.46284488 |
183 | positive regulation of exocytosis (GO:0045921) | 2.44308226 |
184 | dopamine transport (GO:0015872) | 10.1518482 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.54385359 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.70645384 |
3 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.14869697 |
4 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.03724537 |
5 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.97325596 |
6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.88935401 |
7 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 2.87804975 |
8 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.63377976 |
9 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.50504651 |
10 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.40762340 |
11 | * NR3C1_23031785_ChIP-Seq_PC12_Mouse | 2.30704027 |
12 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.30502974 |
13 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.30019009 |
14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.28121757 |
15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.19910412 |
16 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.17875417 |
17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.17800521 |
18 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.12313234 |
19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.07977220 |
20 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.07400160 |
21 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.03809071 |
22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.99550512 |
23 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.93598694 |
24 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.91000113 |
25 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.90594680 |
26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.88646776 |
27 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.85924160 |
28 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.84424290 |
29 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.83534102 |
30 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.82963263 |
31 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.80778044 |
32 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.79409575 |
33 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.77798492 |
34 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.73147073 |
35 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.72765271 |
36 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.70527096 |
37 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.66452462 |
38 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.65085922 |
39 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.64293125 |
40 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.63966213 |
41 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.63360361 |
42 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.63360361 |
43 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.60785967 |
44 | P300_19829295_ChIP-Seq_ESCs_Human | 1.60749123 |
45 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.55773366 |
46 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.53278155 |
47 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.53222905 |
48 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.51594737 |
49 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.48882755 |
50 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.42890163 |
51 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.41401720 |
52 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.39769696 |
53 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.38581226 |
54 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.37887526 |
55 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.37844451 |
56 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.36101553 |
57 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.35778211 |
58 | * AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.34901036 |
59 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.32223952 |
60 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.30849273 |
61 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.30602440 |
62 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.29459626 |
63 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.29393798 |
64 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.29289274 |
65 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.28557244 |
66 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.28153809 |
67 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 1.26783108 |
68 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.26567580 |
69 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.24878481 |
70 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.24841285 |
71 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.24595568 |
72 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21854305 |
73 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20226343 |
74 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.19660752 |
75 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.18962763 |
76 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.18857167 |
77 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.17723781 |
78 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.15888525 |
79 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.15749387 |
80 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.08402501 |
81 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.07872299 |
82 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.07842483 |
83 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.07770582 |
84 | AR_25329375_ChIP-Seq_VCAP_Human | 1.07490563 |
85 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.05912331 |
86 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.05577455 |
87 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.04156165 |
88 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.03973315 |
89 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.03355734 |
90 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03288701 |
91 | RXR_22108803_ChIP-Seq_LS180_Human | 1.03114729 |
92 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.03079679 |
93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.00770035 |
94 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.00190070 |
95 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.99185371 |
96 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.98319089 |
97 | GATA1_22025678_ChIP-Seq_K562_Human | 0.97641509 |
98 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.97532388 |
99 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.97506432 |
100 | * STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.97190665 |
101 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.97091328 |
102 | TCF4_23295773_ChIP-Seq_U87_Human | 0.96689464 |
103 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.96396172 |
104 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.96254028 |
105 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.94970194 |
106 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.94300743 |
107 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93699072 |
108 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.93605060 |
109 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.93601986 |
110 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92783102 |
111 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.92175690 |
112 | JUN_21703547_ChIP-Seq_K562_Human | 0.92143615 |
113 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.91227099 |
114 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.91083025 |
115 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.91033379 |
116 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.90193476 |
117 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.90160689 |
118 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.89839890 |
119 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.89549240 |
120 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.88971857 |
121 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88839520 |
122 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.87794623 |
123 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.86910746 |
124 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.86715478 |
125 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.86570649 |
126 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85511263 |
127 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85154822 |
128 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85025333 |
129 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.84097324 |
130 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.83921483 |
131 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.83677002 |
132 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.83249321 |
133 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.81464938 |
134 | KDM2B_26808549_Chip-Seq_REH_Human | 0.80996220 |
135 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.80069041 |
136 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.79406603 |
137 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.78409573 |
138 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.78375182 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 5.71777067 |
2 | MP0001905_abnormal_dopamine_level | 4.55908180 |
3 | MP0002822_catalepsy | 4.41805245 |
4 | MP0006276_abnormal_autonomic_nervous | 4.01241947 |
5 | MP0001529_abnormal_vocalization | 3.19682039 |
6 | MP0002909_abnormal_adrenal_gland | 3.11463755 |
7 | MP0004019_abnormal_vitamin_homeostasis | 3.01125153 |
8 | MP0001501_abnormal_sleep_pattern | 2.88134955 |
9 | MP0003122_maternal_imprinting | 2.76224483 |
10 | MP0010386_abnormal_urinary_bladder | 2.63177837 |
11 | MP0009379_abnormal_foot_pigmentation | 2.58280105 |
12 | MP0003880_abnormal_central_pattern | 2.41546397 |
13 | MP0010329_abnormal_lipoprotein_level | 2.39363338 |
14 | MP0002837_dystrophic_cardiac_calcinosis | 2.38711736 |
15 | MP0002638_abnormal_pupillary_reflex | 2.36964887 |
16 | MP0002733_abnormal_thermal_nociception | 2.25758637 |
17 | MP0005535_abnormal_body_temperature | 2.24400250 |
18 | MP0000566_synostosis | 2.21468991 |
19 | MP0003011_delayed_dark_adaptation | 2.06519131 |
20 | MP0004924_abnormal_behavior | 2.01208441 |
21 | MP0005386_behavior/neurological_phenoty | 2.01208441 |
22 | MP0004264_abnormal_extraembryonic_tissu | 1.99158625 |
23 | MP0003635_abnormal_synaptic_transmissio | 1.94310672 |
24 | MP0003195_calcinosis | 1.93470823 |
25 | MP0005379_endocrine/exocrine_gland_phen | 1.91562146 |
26 | MP0000538_abnormal_urinary_bladder | 1.88355001 |
27 | MP0002572_abnormal_emotion/affect_behav | 1.86072073 |
28 | MP0005646_abnormal_pituitary_gland | 1.80332226 |
29 | MP0003868_abnormal_feces_composition | 1.76048955 |
30 | MP0009840_abnormal_foam_cell | 1.73540869 |
31 | MP0004270_analgesia | 1.72074394 |
32 | MP0009046_muscle_twitch | 1.72033412 |
33 | MP0000013_abnormal_adipose_tissue | 1.71512816 |
34 | MP0003283_abnormal_digestive_organ | 1.70828103 |
35 | MP0009745_abnormal_behavioral_response | 1.70666631 |
36 | MP0004859_abnormal_synaptic_plasticity | 1.69320686 |
37 | MP0005085_abnormal_gallbladder_physiolo | 1.69166906 |
38 | MP0005360_urolithiasis | 1.68347586 |
39 | MP0002693_abnormal_pancreas_physiology | 1.62679782 |
40 | MP0002064_seizures | 1.60484663 |
41 | MP0004147_increased_porphyrin_level | 1.60131563 |
42 | MP0002272_abnormal_nervous_system | 1.57611365 |
43 | MP0001440_abnormal_grooming_behavior | 1.54714678 |
44 | MP0009780_abnormal_chondrocyte_physiolo | 1.53136808 |
45 | MP0003183_abnormal_peptide_metabolism | 1.52105705 |
46 | MP0004043_abnormal_pH_regulation | 1.51431063 |
47 | MP0002063_abnormal_learning/memory/cond | 1.45875781 |
48 | MP0008872_abnormal_physiological_respon | 1.45182609 |
49 | MP0002734_abnormal_mechanical_nocicepti | 1.43262414 |
50 | MP0001970_abnormal_pain_threshold | 1.41823166 |
51 | MP0001188_hyperpigmentation | 1.40914720 |
52 | MP0009643_abnormal_urine_homeostasis | 1.39978616 |
53 | MP0002557_abnormal_social/conspecific_i | 1.36858279 |
54 | MP0005365_abnormal_bile_salt | 1.36564521 |
55 | MP0001944_abnormal_pancreas_morphology | 1.36005492 |
56 | MP0001764_abnormal_homeostasis | 1.33219310 |
57 | MP0003879_abnormal_hair_cell | 1.31698766 |
58 | MP0005409_darkened_coat_color | 1.31468757 |
59 | MP0008875_abnormal_xenobiotic_pharmacok | 1.31039099 |
60 | MP0005248_abnormal_Harderian_gland | 1.30946628 |
61 | MP0003890_abnormal_embryonic-extraembry | 1.25742733 |
62 | MP0005645_abnormal_hypothalamus_physiol | 1.25644330 |
63 | MP0001486_abnormal_startle_reflex | 1.25257771 |
64 | MP0002751_abnormal_autonomic_nervous | 1.23148881 |
65 | MP0000639_abnormal_adrenal_gland | 1.19553933 |
66 | MP0001666_abnormal_nutrient_absorption | 1.18752887 |
67 | MP0002067_abnormal_sensory_capabilities | 1.17126348 |
68 | MP0002163_abnormal_gland_morphology | 1.15997798 |
69 | MP0002184_abnormal_innervation | 1.13302374 |
70 | MP0001664_abnormal_digestion | 1.12905576 |
71 | MP0003123_paternal_imprinting | 1.10041734 |
72 | MP0003252_abnormal_bile_duct | 1.09495023 |
73 | MP0002078_abnormal_glucose_homeostasis | 1.08818488 |
74 | MP0003718_maternal_effect | 1.06771006 |
75 | MP0005423_abnormal_somatic_nervous | 1.05078644 |
76 | MP0005220_abnormal_exocrine_pancreas | 1.03392818 |
77 | MP0000631_abnormal_neuroendocrine_gland | 1.02962208 |
78 | MP0006072_abnormal_retinal_apoptosis | 1.02828647 |
79 | MP0003953_abnormal_hormone_level | 1.01625281 |
80 | MP0002138_abnormal_hepatobiliary_system | 1.01293884 |
81 | MP0004142_abnormal_muscle_tone | 1.00242848 |
82 | MP0005083_abnormal_biliary_tract | 0.98160666 |
83 | MP0004858_abnormal_nervous_system | 0.97354390 |
84 | MP0001485_abnormal_pinna_reflex | 0.93799371 |
85 | MP0003121_genomic_imprinting | 0.93398040 |
86 | MP0002877_abnormal_melanocyte_morpholog | 0.93254058 |
87 | MP0001502_abnormal_circadian_rhythm | 0.92675304 |
88 | MP0005670_abnormal_white_adipose | 0.92294516 |
89 | MP0002066_abnormal_motor_capabilities/c | 0.92097168 |
90 | MP0002090_abnormal_vision | 0.90810862 |
91 | MP0000569_abnormal_digit_pigmentation | 0.89898302 |
92 | MP0000462_abnormal_digestive_system | 0.87889155 |
93 | MP0003329_amyloid_beta_deposits | 0.87607215 |
94 | MP0001968_abnormal_touch/_nociception | 0.87396773 |
95 | MP0000609_abnormal_liver_physiology | 0.87031707 |
96 | MP0002876_abnormal_thyroid_physiology | 0.85800806 |
97 | MP0003632_abnormal_nervous_system | 0.83651029 |
98 | MP0000955_abnormal_spinal_cord | 0.82022040 |
99 | MP0003315_abnormal_perineum_morphology | 0.80870377 |
100 | MP0004742_abnormal_vestibular_system | 0.79784980 |
101 | MP0002069_abnormal_eating/drinking_beha | 0.78507453 |
102 | MP0001765_abnormal_ion_homeostasis | 0.77121881 |
103 | MP0003959_abnormal_lean_body | 0.76214590 |
104 | MP0005187_abnormal_penis_morphology | 0.75277490 |
105 | MP0005332_abnormal_amino_acid | 0.75122418 |
106 | MP0004133_heterotaxia | 0.74377762 |
107 | MP0005636_abnormal_mineral_homeostasis | 0.73861636 |
108 | MP0000230_abnormal_systemic_arterial | 0.73628568 |
109 | MP0003631_nervous_system_phenotype | 0.71923992 |
110 | MP0002882_abnormal_neuron_morphology | 0.71162445 |
111 | MP0009642_abnormal_blood_homeostasis | 0.70527169 |
112 | MP0002229_neurodegeneration | 0.70509503 |
113 | MP0004811_abnormal_neuron_physiology | 0.70496097 |
114 | MP0001756_abnormal_urination | 0.70413506 |
115 | MP0002735_abnormal_chemical_nociception | 0.69033224 |
116 | MP0002736_abnormal_nociception_after | 0.67023234 |
117 | MP0000778_abnormal_nervous_system | 0.66222898 |
118 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.66115751 |
119 | MP0000477_abnormal_intestine_morphology | 0.64312035 |
120 | MP0003866_abnormal_defecation | 0.63645359 |
121 | MP0005448_abnormal_energy_balance | 0.63632584 |
122 | MP0002136_abnormal_kidney_physiology | 0.63399154 |
123 | MP0004085_abnormal_heartbeat | 0.63139837 |
124 | MP0002118_abnormal_lipid_homeostasis | 0.62236462 |
125 | MP0003567_abnormal_fetal_cardiomyocyte | 0.62112454 |
126 | MP0001270_distended_abdomen | 0.62001291 |
127 | MP0001299_abnormal_eye_distance/ | 0.61663745 |
128 | MP0003633_abnormal_nervous_system | 0.61160828 |
129 | MP0003638_abnormal_response/metabolism_ | 0.61138994 |
130 | MP0002938_white_spotting | 0.60103975 |
131 | MP0005551_abnormal_eye_electrophysiolog | 0.58112532 |
132 | MP0000490_abnormal_crypts_of | 0.57371512 |
133 | MP0005319_abnormal_enzyme/_coenzyme | 0.55739159 |
134 | MP0003938_abnormal_ear_development | 0.54738188 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Limb dystonia (HP:0002451) | 8.42098512 |
2 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 7.40755506 |
3 | Pheochromocytoma (HP:0002666) | 5.59864040 |
4 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 5.24921066 |
5 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 5.12866574 |
6 | Abnormality of proline metabolism (HP:0010907) | 5.05794404 |
7 | Hydroxyprolinuria (HP:0003080) | 5.05794404 |
8 | Neuroendocrine neoplasm (HP:0100634) | 5.01898842 |
9 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 4.50167178 |
10 | * Hypothermia (HP:0002045) | 4.39244588 |
11 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 4.29609564 |
12 | Fat malabsorption (HP:0002630) | 4.24069417 |
13 | Hyperinsulinemic hypoglycemia (HP:0000825) | 4.19092590 |
14 | Visual hallucinations (HP:0002367) | 4.05439105 |
15 | Hyperglycinuria (HP:0003108) | 4.02912147 |
16 | Failure to thrive in infancy (HP:0001531) | 3.86185716 |
17 | Hypoglycemic seizures (HP:0002173) | 3.74678659 |
18 | Proximal tubulopathy (HP:0000114) | 3.73576744 |
19 | Facial shape deformation (HP:0011334) | 3.72193218 |
20 | Potter facies (HP:0002009) | 3.72193218 |
21 | Malnutrition (HP:0004395) | 3.69356744 |
22 | Abnormality of glycine metabolism (HP:0010895) | 3.69327553 |
23 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.69327553 |
24 | Widely patent fontanelles and sutures (HP:0004492) | 3.69312615 |
25 | Acanthocytosis (HP:0001927) | 3.57761390 |
26 | Deep venous thrombosis (HP:0002625) | 3.54794300 |
27 | Orthostatic hypotension (HP:0001278) | 3.49229660 |
28 | Hypokinesia (HP:0002375) | 3.48514094 |
29 | Symptomatic seizures (HP:0011145) | 3.47719296 |
30 | Hypoglycemic coma (HP:0001325) | 3.46375385 |
31 | Hyperactive renin-angiotensin system (HP:0000841) | 3.45456883 |
32 | Agitation (HP:0000713) | 3.44478501 |
33 | Metabolic alkalosis (HP:0200114) | 3.41107395 |
34 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 3.33847040 |
35 | Alkalosis (HP:0001948) | 3.32998702 |
36 | Decreased circulating renin level (HP:0003351) | 3.30987434 |
37 | Abnormality of vitamin B metabolism (HP:0004340) | 3.29384036 |
38 | Complement deficiency (HP:0004431) | 3.28132553 |
39 | Hypolipoproteinemia (HP:0010981) | 3.24394932 |
40 | Abnormality of vitamin metabolism (HP:0100508) | 3.22828142 |
41 | Ketoacidosis (HP:0001993) | 3.18688113 |
42 | Cerebral hemorrhage (HP:0001342) | 3.17992455 |
43 | Postural tremor (HP:0002174) | 3.09067320 |
44 | Acute necrotizing encephalopathy (HP:0006965) | 3.08475480 |
45 | Systemic lupus erythematosus (HP:0002725) | 3.06534937 |
46 | Glomerulonephritis (HP:0000099) | 3.02465821 |
47 | Abnormal autonomic nervous system physiology (HP:0012332) | 2.99157379 |
48 | Abnormality of renin-angiotensin system (HP:0000847) | 2.95671303 |
49 | Confusion (HP:0001289) | 2.95659729 |
50 | Cerebral inclusion bodies (HP:0100314) | 2.94518301 |
51 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.93264499 |
52 | Abnormality of the parathyroid morphology (HP:0011766) | 2.88456250 |
53 | Hyperammonemia (HP:0001987) | 2.85845351 |
54 | Hypercortisolism (HP:0001578) | 2.83672844 |
55 | Acute encephalopathy (HP:0006846) | 2.81919820 |
56 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.77998081 |
57 | Hyperparathyroidism (HP:0000843) | 2.76114077 |
58 | Delayed gross motor development (HP:0002194) | 2.72253859 |
59 | Hypoventilation (HP:0002791) | 2.70158462 |
60 | Steatorrhea (HP:0002570) | 2.70095364 |
61 | Progressive macrocephaly (HP:0004481) | 2.64989604 |
62 | Diminished movement (HP:0002374) | 2.64310225 |
63 | * Muscular hypotonia of the trunk (HP:0008936) | 2.63413530 |
64 | Mitochondrial inheritance (HP:0001427) | 2.62522067 |
65 | Anxiety (HP:0000739) | 2.56681172 |
66 | Hyperventilation (HP:0002883) | 2.55086239 |
67 | Nausea (HP:0002018) | 2.54359164 |
68 | Myokymia (HP:0002411) | 2.53591683 |
69 | Focal segmental glomerulosclerosis (HP:0000097) | 2.49219195 |
70 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.48173010 |
71 | Epidermoid cyst (HP:0200040) | 2.47313944 |
72 | Late onset (HP:0003584) | 2.46657616 |
73 | Nephrolithiasis (HP:0000787) | 2.46532116 |
74 | Ketosis (HP:0001946) | 2.46214075 |
75 | Enlarged epiphyses (HP:0010580) | 2.44864784 |
76 | Rigidity (HP:0002063) | 2.42674778 |
77 | Conjugated hyperbilirubinemia (HP:0002908) | 2.41585939 |
78 | Ileus (HP:0002595) | 2.40115226 |
79 | Hyperphosphaturia (HP:0003109) | 2.39919359 |
80 | Congenital sensorineural hearing impairment (HP:0008527) | 2.39903922 |
81 | Abnormality of complement system (HP:0005339) | 2.37631574 |
82 | Hyperglycinemia (HP:0002154) | 2.37158821 |
83 | Poor suck (HP:0002033) | 2.36562133 |
84 | Intrahepatic cholestasis (HP:0001406) | 2.32957226 |
85 | Cerebral edema (HP:0002181) | 2.32449887 |
86 | Metabolic acidosis (HP:0001942) | 2.31808704 |
87 | Wide cranial sutures (HP:0010537) | 2.31100072 |
88 | Neoplasm of the peripheral nervous system (HP:0100007) | 2.29846773 |
89 | Osteomalacia (HP:0002749) | 2.28302833 |
90 | Neonatal hypoglycemia (HP:0001998) | 2.27407009 |
91 | Renal tubular dysfunction (HP:0000124) | 2.27311814 |
92 | Abnormality of purine metabolism (HP:0004352) | 2.27160284 |
93 | Hyperuricemia (HP:0002149) | 2.25474064 |
94 | Increased purine levels (HP:0004368) | 2.25474064 |
95 | Abnormality of nucleobase metabolism (HP:0010932) | 2.25209940 |
96 | Increased hepatocellular lipid droplets (HP:0006565) | 2.23921335 |
97 | Hypophosphatemia (HP:0002148) | 2.22610233 |
98 | Lipid accumulation in hepatocytes (HP:0006561) | 2.21997796 |
99 | Hyperglycemia (HP:0003074) | 2.21008207 |
100 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.20954644 |
101 | Dysautonomia (HP:0002459) | 2.20000914 |
102 | Spontaneous abortion (HP:0005268) | 2.19561959 |
103 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.19514405 |
104 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.19514405 |
105 | Thin bony cortex (HP:0002753) | 2.18593317 |
106 | Abnormality of magnesium homeostasis (HP:0004921) | 2.17839424 |
107 | Hepatic necrosis (HP:0002605) | 2.16096921 |
108 | Vascular calcification (HP:0004934) | 2.14785116 |
109 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.13947723 |
110 | Pigmentary retinal degeneration (HP:0001146) | 2.13621755 |
111 | Lethargy (HP:0001254) | 2.13415207 |
112 | Neonatal onset (HP:0003623) | 2.11839677 |
113 | Delayed CNS myelination (HP:0002188) | 2.11819923 |
114 | Delayed epiphyseal ossification (HP:0002663) | 2.10591692 |
115 | Glycosuria (HP:0003076) | 2.09797209 |
116 | Abnormality of urine glucose concentration (HP:0011016) | 2.09797209 |
117 | EEG with generalized epileptiform discharges (HP:0011198) | 2.09645894 |
118 | Increased CSF lactate (HP:0002490) | 2.08885633 |
119 | Rickets (HP:0002748) | 2.08199744 |
120 | Progressive cerebellar ataxia (HP:0002073) | 2.07953281 |
121 | Chronic diarrhea (HP:0002028) | 2.06596419 |
122 | Abnormality of the intrinsic pathway (HP:0010989) | 2.05915801 |
123 | Hemorrhage of the eye (HP:0011885) | 2.04414577 |
124 | Dyskinesia (HP:0100660) | 2.03443375 |
125 | Bradykinesia (HP:0002067) | 2.03150767 |
126 | Restlessness (HP:0000711) | 2.02796919 |
127 | Hypsarrhythmia (HP:0002521) | 2.02541220 |
128 | * Hypotension (HP:0002615) | 2.02313996 |
129 | Increased intramyocellular lipid droplets (HP:0012240) | 2.02151084 |
130 | Focal seizures (HP:0007359) | 2.01157391 |
131 | Megaloblastic anemia (HP:0001889) | 2.00660233 |
132 | Prolonged partial thromboplastin time (HP:0003645) | 2.00627113 |
133 | Gout (HP:0001997) | 2.00308482 |
134 | Hepatocellular necrosis (HP:0001404) | 2.00016031 |
135 | Epileptiform EEG discharges (HP:0011182) | 1.99880640 |
136 | Neurofibrillary tangles (HP:0002185) | 1.98747059 |
137 | Abnormal urine phosphate concentration (HP:0012599) | 1.97134773 |
138 | Hyperaldosteronism (HP:0000859) | 1.97010608 |
139 | Skin nodule (HP:0200036) | 1.95693576 |
140 | Generalized tonic-clonic seizures (HP:0002069) | 1.94738439 |
141 | Renal Fanconi syndrome (HP:0001994) | 1.94568565 |
142 | Delusions (HP:0000746) | 1.93405278 |
143 | Cerebral palsy (HP:0100021) | 1.93053778 |
144 | Craniofacial dystonia (HP:0012179) | 1.91987240 |
145 | Hyperlipoproteinemia (HP:0010980) | 1.91719072 |
146 | Polyphagia (HP:0002591) | 1.91451160 |
147 | Torticollis (HP:0000473) | 1.88890752 |
148 | Xanthomatosis (HP:0000991) | 1.88237262 |
149 | Generalized aminoaciduria (HP:0002909) | 1.87871513 |
150 | Hypokalemia (HP:0002900) | 1.87701015 |
151 | Amblyopia (HP:0000646) | 1.85440305 |
152 | Glomerulosclerosis (HP:0000096) | 1.85167102 |
153 | Nephritis (HP:0000123) | 1.84765395 |
154 | Goiter (HP:0000853) | 1.84142598 |
155 | Joint hemorrhage (HP:0005261) | 1.84113167 |
156 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.83350246 |
157 | Supranuclear gaze palsy (HP:0000605) | 1.82565289 |
158 | Thyroid carcinoma (HP:0002890) | 1.82558057 |
159 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.81984819 |
160 | Abnormality of chloride homeostasis (HP:0011422) | 1.81362293 |
161 | Hypobetalipoproteinemia (HP:0003563) | 1.81286600 |
162 | Genital tract atresia (HP:0001827) | 1.81140446 |
163 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.80034706 |
164 | * Irritability (HP:0000737) | 1.79576588 |
165 | Oligomenorrhea (HP:0000876) | 1.78525479 |
166 | Adrenal overactivity (HP:0002717) | 1.77840063 |
167 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.77401775 |
168 | Increased muscle lipid content (HP:0009058) | 1.77119921 |
169 | Vaginal atresia (HP:0000148) | 1.77082526 |
170 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.76976791 |
171 | Dicarboxylic aciduria (HP:0003215) | 1.76976791 |
172 | Concave nail (HP:0001598) | 1.76799983 |
173 | Abnormality of serum amino acid levels (HP:0003112) | 1.75936419 |
174 | Depression (HP:0000716) | 1.75851553 |
175 | Menstrual irregularities (HP:0000858) | 1.75203099 |
176 | Abnormality of the common coagulation pathway (HP:0010990) | 1.75074326 |
177 | Focal dystonia (HP:0004373) | 1.74656858 |
178 | * Myoclonus (HP:0001336) | 1.73140549 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ACVR1B | 4.70558813 |
2 | MAPKAPK5 | 4.46693716 |
3 | INSRR | 3.93481927 |
4 | PNCK | 3.50811349 |
5 | CSNK1G3 | 3.46426714 |
6 | NTRK1 | 3.25150251 |
7 | GRK5 | 3.24292577 |
8 | CSNK1G2 | 3.01419046 |
9 | MAP3K12 | 2.70443358 |
10 | WNK4 | 2.63714341 |
11 | CSNK1G1 | 2.60760256 |
12 | MAP3K4 | 2.45644485 |
13 | NTRK3 | 2.38997505 |
14 | UHMK1 | 2.16061468 |
15 | ERN1 | 1.96597012 |
16 | PASK | 1.95064707 |
17 | MST1R | 1.92054264 |
18 | MAP2K4 | 1.91458640 |
19 | GRK6 | 1.83327842 |
20 | MAPK15 | 1.82396096 |
21 | WNK3 | 1.78638171 |
22 | TLK1 | 1.77993573 |
23 | STK39 | 1.74729633 |
24 | MAP2K7 | 1.73408608 |
25 | PRKD3 | 1.73205109 |
26 | EPHB2 | 1.72230085 |
27 | GRK1 | 1.72209107 |
28 | MINK1 | 1.65768857 |
29 | CAMK2A | 1.64142599 |
30 | DAPK2 | 1.57440979 |
31 | MAP3K9 | 1.56892507 |
32 | ARAF | 1.56489575 |
33 | RET | 1.48437317 |
34 | DYRK2 | 1.47965086 |
35 | PRKG2 | 1.47645974 |
36 | GRK7 | 1.37191939 |
37 | PAK3 | 1.34358550 |
38 | FGR | 1.33789342 |
39 | ADRBK2 | 1.31581678 |
40 | PIK3CA | 1.31420334 |
41 | MARK1 | 1.30603802 |
42 | NME1 | 1.28227916 |
43 | CAMK2B | 1.25772304 |
44 | MAP3K2 | 1.24239161 |
45 | PTK2 | 1.22264420 |
46 | CAMK2D | 1.22140614 |
47 | DYRK1B | 1.20318388 |
48 | EPHA2 | 1.16664902 |
49 | ADRBK1 | 1.15937245 |
50 | MAP3K10 | 1.14567626 |
51 | PLK2 | 1.11320430 |
52 | HIPK2 | 1.10434362 |
53 | ERBB2 | 1.10067834 |
54 | TAOK3 | 1.03940253 |
55 | NTRK2 | 0.99300032 |
56 | CAMK2G | 0.98670493 |
57 | PINK1 | 0.97939904 |
58 | CDK5 | 0.96750949 |
59 | CASK | 0.95841704 |
60 | ERBB4 | 0.94888793 |
61 | SGK2 | 0.93583580 |
62 | PTK6 | 0.85242992 |
63 | CDK14 | 0.84920696 |
64 | MAPK13 | 0.83629972 |
65 | RIPK1 | 0.83118187 |
66 | PRKCG | 0.82512788 |
67 | OXSR1 | 0.82259940 |
68 | MAP3K11 | 0.81820911 |
69 | PDK2 | 0.80878850 |
70 | TNIK | 0.80136178 |
71 | CDK15 | 0.79884355 |
72 | WNK1 | 0.79094236 |
73 | CDK18 | 0.78316678 |
74 | BCR | 0.77747118 |
75 | MAP3K1 | 0.77213144 |
76 | FRK | 0.76722664 |
77 | BCKDK | 0.74381604 |
78 | DDR2 | 0.71621265 |
79 | CDK11A | 0.69629084 |
80 | FGFR3 | 0.68029241 |
81 | IRAK2 | 0.66442956 |
82 | KSR2 | 0.66432576 |
83 | EPHA4 | 0.65295862 |
84 | MAP2K6 | 0.64974897 |
85 | PTK2B | 0.64265622 |
86 | DYRK1A | 0.62282067 |
87 | LMTK2 | 0.62155061 |
88 | PRKCE | 0.61301965 |
89 | PRKAA2 | 0.61224570 |
90 | CAMKK2 | 0.59995800 |
91 | MAP2K2 | 0.59510122 |
92 | PRKACA | 0.55470981 |
93 | MAP2K1 | 0.53071695 |
94 | BMPR1B | 0.52994151 |
95 | CSNK1A1 | 0.51186647 |
96 | PRKCH | 0.49194009 |
97 | TESK1 | 0.49068578 |
98 | ERBB3 | 0.48823577 |
99 | RPS6KA5 | 0.47844244 |
100 | SIK1 | 0.46304539 |
101 | CAMK4 | 0.45068037 |
102 | SGK223 | 0.43217771 |
103 | SGK494 | 0.43217771 |
104 | DYRK3 | 0.43126834 |
105 | PRKACG | 0.42178562 |
106 | TYRO3 | 0.41596200 |
107 | AKT3 | 0.41428210 |
108 | CSNK1E | 0.41246725 |
109 | PDGFRA | 0.40719192 |
110 | CDC42BPA | 0.40215701 |
111 | CAMK1G | 0.40138878 |
112 | STK16 | 0.39970040 |
113 | PRKCZ | 0.39589774 |
114 | BRAF | 0.38852662 |
115 | PDPK1 | 0.38598779 |
116 | EPHB1 | 0.38404887 |
117 | PRKCA | 0.36838301 |
118 | RPS6KA2 | 0.36588846 |
119 | SGK3 | 0.35908097 |
120 | PRKG1 | 0.35852947 |
121 | MET | 0.35662975 |
122 | CSNK1A1L | 0.34626637 |
123 | SCYL2 | 0.34302150 |
124 | SGK1 | 0.34297110 |
125 | TAOK1 | 0.34160462 |
126 | PHKG2 | 0.34108956 |
127 | PHKG1 | 0.34108956 |
128 | IGF1R | 0.32306405 |
129 | FER | 0.31449876 |
130 | CHUK | 0.31096786 |
131 | TESK2 | 0.30803453 |
132 | MATK | 0.30281764 |
133 | PAK6 | 0.29519709 |
134 | FGFR4 | 0.29515609 |
135 | PRKCB | 0.28910941 |
136 | PKN1 | 0.28098661 |
137 | IRAK1 | 0.27628005 |
138 | LATS2 | 0.27525112 |
139 | GSK3A | 0.27522410 |
140 | TSSK6 | 0.26406822 |
141 | PRKAA1 | 0.25634998 |
142 | SIK2 | 0.25329122 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 4.10269399 |
2 | * Cocaine addiction_Homo sapiens_hsa05030 | 3.53053245 |
3 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 3.12827825 |
4 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.99892248 |
5 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.87700982 |
6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.82944820 |
7 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.74823111 |
8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.72148085 |
9 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.45313397 |
10 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.43245331 |
11 | * Tyrosine metabolism_Homo sapiens_hsa00350 | 2.39753787 |
12 | * Amphetamine addiction_Homo sapiens_hsa05031 | 2.36373784 |
13 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.34955789 |
14 | Protein export_Homo sapiens_hsa03060 | 2.33898853 |
15 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.26280488 |
16 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.11110476 |
17 | Insulin secretion_Homo sapiens_hsa04911 | 2.03120367 |
18 | * Tryptophan metabolism_Homo sapiens_hsa00380 | 2.02328624 |
19 | * Serotonergic synapse_Homo sapiens_hsa04726 | 2.01025429 |
20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.97458786 |
21 | * Dopaminergic synapse_Homo sapiens_hsa04728 | 1.96300850 |
22 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.92861740 |
23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.80129007 |
24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.79509484 |
25 | Mineral absorption_Homo sapiens_hsa04978 | 1.79410589 |
26 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.78586583 |
27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.72798115 |
28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.61216960 |
29 | * Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.59329018 |
30 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.58232496 |
31 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.55312079 |
32 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.54747119 |
33 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.42674663 |
34 | * Histidine metabolism_Homo sapiens_hsa00340 | 1.41696771 |
35 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.39185773 |
36 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.34103598 |
37 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.33204616 |
38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.32858887 |
39 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.30045534 |
40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.29523380 |
41 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.25528058 |
42 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.23613691 |
43 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.22986302 |
44 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.16910385 |
45 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.16195239 |
46 | GABAergic synapse_Homo sapiens_hsa04727 | 1.16085872 |
47 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14764784 |
48 | Nicotine addiction_Homo sapiens_hsa05033 | 1.05412353 |
49 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.03660721 |
50 | Taste transduction_Homo sapiens_hsa04742 | 1.02971774 |
51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.00120416 |
52 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.99948372 |
53 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.99530049 |
54 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.98647392 |
55 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.97843298 |
56 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.97214178 |
57 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.95165207 |
58 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.92087134 |
59 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.90638777 |
60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90356953 |
61 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.88450658 |
62 | Circadian entrainment_Homo sapiens_hsa04713 | 0.86567142 |
63 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.84002196 |
64 | Bile secretion_Homo sapiens_hsa04976 | 0.83423739 |
65 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.83374579 |
66 | * Alcoholism_Homo sapiens_hsa05034 | 0.82135210 |
67 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.79839192 |
68 | Long-term depression_Homo sapiens_hsa04730 | 0.79339230 |
69 | Renin secretion_Homo sapiens_hsa04924 | 0.79004287 |
70 | Gap junction_Homo sapiens_hsa04540 | 0.77596175 |
71 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.77401500 |
72 | Peroxisome_Homo sapiens_hsa04146 | 0.75050171 |
73 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74659842 |
74 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.74409948 |
75 | Long-term potentiation_Homo sapiens_hsa04720 | 0.74398855 |
76 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.72396518 |
77 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.72301712 |
78 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70293607 |
79 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.67445379 |
80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.67133495 |
81 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.66947918 |
82 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.65805346 |
83 | Prion diseases_Homo sapiens_hsa05020 | 0.65606294 |
84 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.65519445 |
85 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.65449730 |
86 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.65174049 |
87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.63410552 |
88 | Morphine addiction_Homo sapiens_hsa05032 | 0.61852350 |
89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.61113580 |
90 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.59732582 |
91 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.59377694 |
92 | Retinol metabolism_Homo sapiens_hsa00830 | 0.58933444 |
93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.55998240 |
94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.54994666 |
95 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.54978701 |
96 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.52844437 |
97 | ABC transporters_Homo sapiens_hsa02010 | 0.51125519 |
98 | Salivary secretion_Homo sapiens_hsa04970 | 0.50639099 |
99 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.50224057 |
100 | Sulfur relay system_Homo sapiens_hsa04122 | 0.49153467 |
101 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.49131380 |
102 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48647895 |
103 | * Metabolic pathways_Homo sapiens_hsa01100 | 0.46510465 |
104 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.45373310 |
105 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44506969 |
106 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.43777702 |
107 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.43690721 |
108 | Phagosome_Homo sapiens_hsa04145 | 0.40271388 |
109 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.40087189 |
110 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.40034890 |
111 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.39727636 |
112 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38983737 |
113 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.38847045 |
114 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.37766162 |
115 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.37573026 |
116 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37377911 |
117 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.37128355 |
118 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.35117529 |
119 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.34447035 |
120 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.33956097 |
121 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.33931011 |
122 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.33920602 |
123 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33562967 |
124 | Galactose metabolism_Homo sapiens_hsa00052 | 0.32415928 |
125 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.29675565 |
126 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29427970 |
127 | Carbon metabolism_Homo sapiens_hsa01200 | 0.29323330 |
128 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.20494217 |