DDIAS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.79708614
2regulation of spindle organization (GO:0090224)4.97477622
3regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.93826417
4protein localization to kinetochore (GO:0034501)4.92335679
5metaphase plate congression (GO:0051310)4.84680412
6nuclear pore organization (GO:0006999)4.76234520
7nuclear pore complex assembly (GO:0051292)4.72162412
8protein localization to chromosome, centromeric region (GO:0071459)4.62148093
9DNA replication checkpoint (GO:0000076)4.55069017
10mitotic sister chromatid segregation (GO:0000070)4.45250600
11mitotic nuclear envelope disassembly (GO:0007077)4.42235714
12purine nucleobase biosynthetic process (GO:0009113)4.33984948
13mitotic chromosome condensation (GO:0007076)4.29378702
14establishment of chromosome localization (GO:0051303)4.26375927
15regulation of mitotic spindle organization (GO:0060236)4.25781812
16positive regulation of chromosome segregation (GO:0051984)4.22543197
17establishment of integrated proviral latency (GO:0075713)4.18348837
18chromatin remodeling at centromere (GO:0031055)4.17221251
19CENP-A containing nucleosome assembly (GO:0034080)4.16293760
20DNA replication initiation (GO:0006270)4.16141825
21regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.15873984
22nucleobase biosynthetic process (GO:0046112)4.14953140
23nuclear envelope disassembly (GO:0051081)4.14138136
24membrane disassembly (GO:0030397)4.14138136
25attachment of spindle microtubules to kinetochore (GO:0008608)4.13088260
26protein K6-linked ubiquitination (GO:0085020)4.09015449
27sister chromatid segregation (GO:0000819)4.02688939
28kinetochore organization (GO:0051383)4.02304180
29DNA replication-dependent nucleosome assembly (GO:0006335)4.00273772
30DNA replication-dependent nucleosome organization (GO:0034723)4.00273772
31ribosome assembly (GO:0042255)3.99896440
32histone exchange (GO:0043486)3.97345921
33nucleotide-excision repair, DNA gap filling (GO:0006297)3.97079926
34DNA replication-independent nucleosome organization (GO:0034724)3.93570204
35DNA replication-independent nucleosome assembly (GO:0006336)3.93570204
36regulation of chromosome segregation (GO:0051983)3.92006921
37DNA ligation (GO:0006266)3.85429945
38spindle checkpoint (GO:0031577)3.83548448
39monoubiquitinated protein deubiquitination (GO:0035520)3.73877519
40regulation of centrosome cycle (GO:0046605)3.73157802
41DNA double-strand break processing (GO:0000729)3.72410865
42somatic hypermutation of immunoglobulin genes (GO:0016446)3.72252342
43somatic diversification of immune receptors via somatic mutation (GO:0002566)3.72252342
44positive regulation of mitotic sister chromatid separation (GO:1901970)3.71377732
45positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.71377732
46positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.71377732
47pore complex assembly (GO:0046931)3.70822768
48DNA strand elongation involved in DNA replication (GO:0006271)3.70287227
49microtubule depolymerization (GO:0007019)3.67641699
50protein localization to chromosome (GO:0034502)3.66535564
51kinetochore assembly (GO:0051382)3.66080134
52meiotic chromosome segregation (GO:0045132)3.65611155
53regulation of DNA endoreduplication (GO:0032875)3.64142237
54regulation of mitotic metaphase/anaphase transition (GO:0030071)3.62993159
55negative regulation of chromosome segregation (GO:0051985)3.62285256
56synapsis (GO:0007129)3.60990021
57negative regulation of DNA-dependent DNA replication (GO:2000104)3.60827058
58negative regulation of mitotic sister chromatid separation (GO:2000816)3.57004839
59negative regulation of mitotic sister chromatid segregation (GO:0033048)3.57004839
60negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.57004839
61negative regulation of sister chromatid segregation (GO:0033046)3.57004839
62regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.56369761
63mitotic spindle checkpoint (GO:0071174)3.56065817
64proteasome assembly (GO:0043248)3.55890934
65mitotic sister chromatid cohesion (GO:0007064)3.55039326
66DNA strand elongation (GO:0022616)3.53547142
67ribosome biogenesis (GO:0042254)3.53544369
68spindle assembly checkpoint (GO:0071173)3.50804671
69negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.48609510
70mitotic spindle assembly checkpoint (GO:0007094)3.47745901
71chromosome segregation (GO:0007059)3.45925590
72non-recombinational repair (GO:0000726)3.43474000
73double-strand break repair via nonhomologous end joining (GO:0006303)3.43474000
74regulation of mitotic sister chromatid separation (GO:0010965)3.42151637
75regulation of mitotic sister chromatid segregation (GO:0033047)3.42151637
76regulation of sister chromatid segregation (GO:0033045)3.42151637
77DNA catabolic process, exonucleolytic (GO:0000738)3.41873413
78anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.40751036
79replication fork processing (GO:0031297)3.40072065
80regulation of centriole replication (GO:0046599)3.40012263
81DNA topological change (GO:0006265)3.37334585
82regulation of mitotic spindle checkpoint (GO:1903504)3.37181681
83regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.37181681
84regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.32697369
85nuclear envelope organization (GO:0006998)3.32015870
86resolution of meiotic recombination intermediates (GO:0000712)3.31475372
87piRNA metabolic process (GO:0034587)3.30831834
88regulation of double-strand break repair via homologous recombination (GO:0010569)3.30217391
89synaptonemal complex assembly (GO:0007130)3.28624182
90DNA unwinding involved in DNA replication (GO:0006268)3.28459459
91chromatin assembly or disassembly (GO:0006333)3.26640678
92negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.26184989
93regulation of sister chromatid cohesion (GO:0007063)3.25930779
94IMP metabolic process (GO:0046040)3.25929239
95telomere maintenance via semi-conservative replication (GO:0032201)3.24802363
96telomere maintenance via recombination (GO:0000722)3.20781918
97mitotic recombination (GO:0006312)3.20558875
98postreplication repair (GO:0006301)3.17230487
99formation of translation preinitiation complex (GO:0001731)3.17201420
100chromosome condensation (GO:0030261)3.13670455
101folic acid metabolic process (GO:0046655)3.12340805
102negative regulation of mitosis (GO:0045839)3.12323208
103maturation of 5.8S rRNA (GO:0000460)3.12024550
104cell cycle G1/S phase transition (GO:0044843)3.11344055
105G1/S transition of mitotic cell cycle (GO:0000082)3.11344055
106maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.10576460
107ATP-dependent chromatin remodeling (GO:0043044)3.06511971
108IMP biosynthetic process (GO:0006188)3.04591211
109regulation of exit from mitosis (GO:0007096)3.04052064
110synaptonemal complex organization (GO:0070193)2.98878698
111regulation of telomere maintenance via telomerase (GO:0032210)2.96185805
112maturation of SSU-rRNA (GO:0030490)2.94791541
113folic acid-containing compound biosynthetic process (GO:0009396)2.94399315
114regulation of RNA export from nucleus (GO:0046831)2.94077533
115meiosis I (GO:0007127)2.93897660
116regulation of histone H3-K9 methylation (GO:0051570)2.90769436
117meiotic cell cycle process (GO:1903046)2.89703421
118rRNA modification (GO:0000154)2.89287246
119histone H2A monoubiquitination (GO:0035518)2.89009517
120mitotic cell cycle (GO:0000278)2.88991725
121mitotic G2/M transition checkpoint (GO:0044818)2.88083748
122DNA packaging (GO:0006323)2.87912403
123telomere maintenance via telomere lengthening (GO:0010833)2.87462942
124histone-serine phosphorylation (GO:0035404)2.87323817
125regulation of spindle checkpoint (GO:0090231)2.86211559
126meiotic nuclear division (GO:0007126)2.85237115

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.01554208
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.70879442
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.15150361
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.91096368
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.79455715
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.75002797
7AR_21909140_ChIP-Seq_LNCAP_Human2.92102094
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.83297337
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.71678187
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.65314678
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.63492017
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.61916118
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.53117895
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.44882143
15KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.43762141
16EST1_17652178_ChIP-ChIP_JURKAT_Human2.39286487
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.38151836
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34411514
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.33950927
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.31265418
21E2F1_21310950_ChIP-Seq_MCF-7_Human2.20664091
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.07648900
23MYCN_18555785_ChIP-Seq_MESCs_Mouse2.07357674
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.07119779
25XRN2_22483619_ChIP-Seq_HELA_Human2.02323834
26VDR_23849224_ChIP-Seq_CD4+_Human2.00793857
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.90951097
28NANOG_18555785_ChIP-Seq_MESCs_Mouse1.89350054
29SALL1_21062744_ChIP-ChIP_HESCs_Human1.88729525
30POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.82358748
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.80230508
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71928265
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.70250311
34GABP_19822575_ChIP-Seq_HepG2_Human1.70238716
35FOXP3_21729870_ChIP-Seq_TREG_Human1.68759855
36DCP1A_22483619_ChIP-Seq_HELA_Human1.67678712
37HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.59318449
38SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.54833711
39TTF2_22483619_ChIP-Seq_HELA_Human1.54111817
40KDM5A_27292631_Chip-Seq_BREAST_Human1.53227973
41CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.50879076
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.50362525
43YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44502173
44CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.44274270
45ELK1_19687146_ChIP-ChIP_HELA_Human1.43586376
46KLF4_18555785_ChIP-Seq_MESCs_Mouse1.40844559
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39796556
48STAT3_1855785_ChIP-Seq_MESCs_Mouse1.39587105
49HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35798984
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.34276559
51POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.33997990
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.31268592
53RBPJ_22232070_ChIP-Seq_NCS_Mouse1.30712984
54EWS_26573619_Chip-Seq_HEK293_Human1.25480137
55SOX2_18555785_ChIP-Seq_MESCs_Mouse1.25148195
56POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.22769248
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.21602716
58ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.19838333
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.19517838
60E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.18428518
61CIITA_25753668_ChIP-Seq_RAJI_Human1.17878968
62MYC_22102868_ChIP-Seq_BL_Human1.17866874
63HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17785988
64ZNF274_21170338_ChIP-Seq_K562_Hela1.17436889
65NANOG_16153702_ChIP-ChIP_HESCs_Human1.17206878
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.16296150
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.16259564
68NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.14413412
69DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13433651
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.12477889
71YY1_21170310_ChIP-Seq_MESCs_Mouse1.12160151
72POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11950093
73CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.11943987
74NANOG_21062744_ChIP-ChIP_HESCs_Human1.10452609
75VDR_22108803_ChIP-Seq_LS180_Human1.06486240
76SOX2_16153702_ChIP-ChIP_HESCs_Human1.05877472
77NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.05559027
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04359087
79ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01538893
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01387103
81NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.00942803
82SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.99788743
83TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.99521261
84TFEB_21752829_ChIP-Seq_HELA_Human0.95179645
85SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94376878
86ZNF263_19887448_ChIP-Seq_K562_Human0.94256841
87FUS_26573619_Chip-Seq_HEK293_Human0.93641670
88SRF_21415370_ChIP-Seq_HL-1_Mouse0.93408154
89SOX17_20123909_ChIP-Seq_XEN_Mouse0.92995062
90CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.92767655
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.92473799
92CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90407193
93NOTCH1_21737748_ChIP-Seq_TLL_Human0.90289491
94KAP1_22055183_ChIP-Seq_ESCs_Mouse0.88474205
95IRF1_19129219_ChIP-ChIP_H3396_Human0.87198530
96TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85593148
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85153827
98ELF1_17652178_ChIP-ChIP_JURKAT_Human0.85072444
99KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.83531794
100KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.83531794
101KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.83531794
102MYC_18940864_ChIP-ChIP_HL60_Human0.82902709
103TCF3_18692474_ChIP-Seq_MESCs_Mouse0.81983119
104NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.81427758
105ERG_20887958_ChIP-Seq_HPC-7_Mouse0.80640758
106BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.80015354
107SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.79320670
108BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.79059222
109TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.75971439
110TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.75952782
111PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.74682126
112KAP1_27257070_Chip-Seq_ESCs_Mouse0.74620588
113CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.74480443
114HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.72042014
115IGF1R_20145208_ChIP-Seq_DFB_Human0.68484375
116FLI1_27457419_Chip-Seq_LIVER_Mouse0.68317774
117HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.67850517
118ESR1_15608294_ChIP-ChIP_MCF-7_Human0.61725813

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.60605638
2MP0003111_abnormal_nucleus_morphology4.83649627
3MP0010094_abnormal_chromosome_stability4.80896782
4MP0004957_abnormal_blastocyst_morpholog4.13709306
5MP0008057_abnormal_DNA_replication4.12566651
6MP0003077_abnormal_cell_cycle4.11294324
7MP0008058_abnormal_DNA_repair3.32638198
8MP0008877_abnormal_DNA_methylation3.01794588
9MP0008007_abnormal_cellular_replicative2.95264022
10MP0003718_maternal_effect2.58085102
11MP0010307_abnormal_tumor_latency2.56181717
12MP0001730_embryonic_growth_arrest2.56080647
13MP0008932_abnormal_embryonic_tissue2.50894532
14MP0003123_paternal_imprinting2.38312504
15MP0000350_abnormal_cell_proliferation2.36118945
16MP0003786_premature_aging2.18953695
17MP0009697_abnormal_copulation2.16804124
18MP0005380_embryogenesis_phenotype2.01580054
19MP0001672_abnormal_embryogenesis/_devel2.01580054
20MP0002210_abnormal_sex_determination1.97160169
21MP0002396_abnormal_hematopoietic_system1.95191361
22MP0001929_abnormal_gametogenesis1.93840558
23MP0001697_abnormal_embryo_size1.87986878
24MP0010352_gastrointestinal_tract_polyps1.82246924
25MP0003984_embryonic_growth_retardation1.75151701
26MP0002088_abnormal_embryonic_growth/wei1.70676662
27MP0002085_abnormal_embryonic_tissue1.69204272
28MP0001145_abnormal_male_reproductive1.68660114
29MP0002084_abnormal_developmental_patter1.67126801
30MP0002080_prenatal_lethality1.61565808
31MP0000653_abnormal_sex_gland1.53730640
32MP0002086_abnormal_extraembryonic_tissu1.53666839
33MP0005410_abnormal_fertilization1.49059016
34MP0006035_abnormal_mitochondrial_morpho1.48051918
35MP0005076_abnormal_cell_differentiation1.47125308
36MP0002653_abnormal_ependyma_morphology1.42099951
37MP0004197_abnormal_fetal_growth/weight/1.38287598
38MP0004808_abnormal_hematopoietic_stem1.37893837
39MP0003121_genomic_imprinting1.36331904
40MP0000313_abnormal_cell_death1.35065458
41MP0003698_abnormal_male_reproductive1.33890877
42MP0000490_abnormal_crypts_of1.31132747
43MP0005397_hematopoietic_system_phenotyp1.29622189
44MP0001545_abnormal_hematopoietic_system1.29622189
45MP0002019_abnormal_tumor_incidence1.27628455
46MP0003136_yellow_coat_color1.26835615
47MP0003567_abnormal_fetal_cardiomyocyte1.25334592
48MP0004147_increased_porphyrin_level1.24499799
49MP0002938_white_spotting1.19287250
50MP0009333_abnormal_splenocyte_physiolog1.15677216
51MP0001293_anophthalmia1.14464695
52MP0003937_abnormal_limbs/digits/tail_de1.13829356
53MP0002160_abnormal_reproductive_system1.11377674
54MP0001119_abnormal_female_reproductive1.10731105
55MP0003315_abnormal_perineum_morphology1.10698744
56MP0001529_abnormal_vocalization1.09693869
57MP0003705_abnormal_hypodermis_morpholog1.07214981
58MP0002102_abnormal_ear_morphology1.06700372
59MP0002161_abnormal_fertility/fecundity1.06069049
60MP0001188_hyperpigmentation1.04220754
61MP0003890_abnormal_embryonic-extraembry0.99415068
62MP0010030_abnormal_orbit_morphology0.97660532
63MP0002697_abnormal_eye_size0.97051345
64MP0001346_abnormal_lacrimal_gland0.95349206
65MP0008789_abnormal_olfactory_epithelium0.94873921
66MP0003941_abnormal_skin_development0.93998688
67MP0006036_abnormal_mitochondrial_physio0.93210601
68MP0005621_abnormal_cell_physiology0.92991561
69MP0003699_abnormal_female_reproductive0.91113035
70MP0003186_abnormal_redox_activity0.88908631
71MP0005389_reproductive_system_phenotype0.88686949
72MP0002233_abnormal_nose_morphology0.88512291
73MP0006072_abnormal_retinal_apoptosis0.87411986
74MP0005395_other_phenotype0.87147478
75MP0005384_cellular_phenotype0.86534252
76MP0009053_abnormal_anal_canal0.86141179
77MP0009672_abnormal_birth_weight0.83376007
78MP0004264_abnormal_extraembryonic_tissu0.82665369
79MP0008260_abnormal_autophagy0.81824167
80MP0003119_abnormal_digestive_system0.80858857
81MP0000428_abnormal_craniofacial_morphol0.79859103
82MP0003221_abnormal_cardiomyocyte_apopto0.78125266
83MP0001915_intracranial_hemorrhage0.76005527
84MP0003878_abnormal_ear_physiology0.75850615
85MP0005377_hearing/vestibular/ear_phenot0.75850615
86MP0000647_abnormal_sebaceous_gland0.75511539
87MP0008995_early_reproductive_senescence0.74512450
88MP0000358_abnormal_cell_content/0.73761684
89MP0009703_decreased_birth_body0.73460807
90MP0002092_abnormal_eye_morphology0.71668278
91MP0005501_abnormal_skin_physiology0.69847650
92MP0000627_abnormal_mammary_gland0.69709551
93MP0000733_abnormal_muscle_development0.69034795
94MP0002163_abnormal_gland_morphology0.68593282
95MP0002111_abnormal_tail_morphology0.67751323
96MP0005023_abnormal_wound_healing0.67345593
97MP0003950_abnormal_plasma_membrane0.67279947
98MP0002751_abnormal_autonomic_nervous0.67064243
99MP0000432_abnormal_head_morphology0.67049783
100MP0000537_abnormal_urethra_morphology0.65607127
101MP0000703_abnormal_thymus_morphology0.65323334
102MP0003936_abnormal_reproductive_system0.63317573
103MP0000049_abnormal_middle_ear0.61562358
104MP0001849_ear_inflammation0.61294856
105MP0003566_abnormal_cell_adhesion0.61045242
106MP0003806_abnormal_nucleotide_metabolis0.61039663
107MP0001286_abnormal_eye_development0.59818915
108MP0005391_vision/eye_phenotype0.58978731
109MP0003943_abnormal_hepatobiliary_system0.58942040
110MP0006292_abnormal_olfactory_placode0.58609541
111MP0002796_impaired_skin_barrier0.58572507
112MP0002722_abnormal_immune_system0.58243390
113MP0003656_abnormal_erythrocyte_physiolo0.57015528
114MP0002398_abnormal_bone_marrow0.56866719
115MP0000750_abnormal_muscle_regeneration0.56629681
116MP0005451_abnormal_body_composition0.56197842
117MP0000689_abnormal_spleen_morphology0.55800537
118MP0001177_atelectasis0.55167819
119MP0009278_abnormal_bone_marrow0.55001493
120MP0003115_abnormal_respiratory_system0.54759208
121MP0003935_abnormal_craniofacial_develop0.54659086
122MP0002132_abnormal_respiratory_system0.54298604
123MP0003755_abnormal_palate_morphology0.53767920
124MP0002234_abnormal_pharynx_morphology0.53598403
125MP0003861_abnormal_nervous_system0.53226723
126MP0000427_abnormal_hair_cycle0.52141752
127MP0004233_abnormal_muscle_weight0.51885362
128MP0000631_abnormal_neuroendocrine_gland0.50310376
129MP0005174_abnormal_tail_pigmentation0.50059098
130MP0005499_abnormal_olfactory_system0.49185599
131MP0005394_taste/olfaction_phenotype0.49185599
132MP0001661_extended_life_span0.48328913

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.45688531
2Breast hypoplasia (HP:0003187)4.60059308
3Chromsome breakage (HP:0040012)4.57207000
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.44588186
5Impulsivity (HP:0100710)4.35574511
6Patellar aplasia (HP:0006443)3.88879131
7Abnormality of chromosome stability (HP:0003220)3.74710423
8Carpal bone hypoplasia (HP:0001498)3.67625434
9Aplasia/Hypoplasia of the patella (HP:0006498)3.67622156
10Abnormality of the labia minora (HP:0012880)3.62727028
11Meckel diverticulum (HP:0002245)3.48458276
12Abnormality of the preputium (HP:0100587)3.43914628
13Aplasia/Hypoplasia of the uvula (HP:0010293)3.35558867
14Abnormality of the ileum (HP:0001549)3.30945836
15Facial hemangioma (HP:0000329)3.25377425
16Degeneration of anterior horn cells (HP:0002398)3.16228304
17Abnormality of the anterior horn cell (HP:0006802)3.16228304
18Absent radius (HP:0003974)3.07651227
19Selective tooth agenesis (HP:0001592)3.02872398
20Duodenal stenosis (HP:0100867)3.01092436
21Small intestinal stenosis (HP:0012848)3.01092436
22Oral leukoplakia (HP:0002745)2.96193591
23Supernumerary spleens (HP:0009799)2.93519859
24Ependymoma (HP:0002888)2.92365535
25Rough bone trabeculation (HP:0100670)2.90732419
26Absent forearm bone (HP:0003953)2.86890806
27Aplasia involving forearm bones (HP:0009822)2.86890806
28Ectopic kidney (HP:0000086)2.76123480
29Myelodysplasia (HP:0002863)2.68988241
30Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.68956823
31Hypoplasia of the capital femoral epiphysis (HP:0003090)2.63038801
32Sloping forehead (HP:0000340)2.62466056
33Abnormal spermatogenesis (HP:0008669)2.61090606
34Medulloblastoma (HP:0002885)2.60539924
35Cortical dysplasia (HP:0002539)2.59056373
36Cerebral hypomyelination (HP:0006808)2.45288551
37Bone marrow hypocellularity (HP:0005528)2.42855865
38Neoplasm of the pancreas (HP:0002894)2.42373796
39Neoplasm of the colon (HP:0100273)2.42240759
40Abnormality of the duodenum (HP:0002246)2.41994749
41Absent thumb (HP:0009777)2.40648556
42Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.36473214
43Colon cancer (HP:0003003)2.36264765
44Prominent nose (HP:0000448)2.35730594
45Rhabdomyosarcoma (HP:0002859)2.34171781
46Entropion (HP:0000621)2.28016597
47Secondary amenorrhea (HP:0000869)2.27916660
48Capillary hemangiomas (HP:0005306)2.27718020
49Abnormality of the carotid arteries (HP:0005344)2.25450929
50Premature ovarian failure (HP:0008209)2.24421006
51Squamous cell carcinoma (HP:0002860)2.22613631
52Male infertility (HP:0003251)2.20874247
53Reticulocytopenia (HP:0001896)2.19843832
54Abnormal trabecular bone morphology (HP:0100671)2.19801715
55Short thumb (HP:0009778)2.19154236
56Cafe-au-lait spot (HP:0000957)2.17495448
57Horseshoe kidney (HP:0000085)2.17337753
58Aplasia/hypoplasia of the humerus (HP:0006507)2.17209383
59Sparse lateral eyebrow (HP:0005338)2.15760457
60Oligodactyly (HP:0012165)2.15433319
61Deviation of the thumb (HP:0009603)2.14713924
62Proximal placement of thumb (HP:0009623)2.14643265
63Agnosia (HP:0010524)2.14111413
64Ureteral duplication (HP:0000073)2.13456101
65Tracheoesophageal fistula (HP:0002575)2.12731096
66Aplasia/Hypoplasia of the sacrum (HP:0008517)2.11409768
67Hypoplasia of the pons (HP:0012110)2.11273202
68Abnormality of the pons (HP:0007361)2.11045594
69Microvesicular hepatic steatosis (HP:0001414)2.10801551
70Breast aplasia (HP:0100783)2.07924089
71Atresia of the external auditory canal (HP:0000413)2.02758391
7211 pairs of ribs (HP:0000878)2.01506329
73Oligodactyly (hands) (HP:0001180)2.01286745
74Embryonal neoplasm (HP:0002898)2.01180747
75Triphalangeal thumb (HP:0001199)2.00905312
76Increased hepatocellular lipid droplets (HP:0006565)2.00517898
77Astrocytoma (HP:0009592)1.98533917
78Abnormality of the astrocytes (HP:0100707)1.98533917
79Increased serum pyruvate (HP:0003542)1.98109938
80Nephroblastoma (Wilms tumor) (HP:0002667)1.97366461
81Aplasia/Hypoplasia of the breasts (HP:0010311)1.97363804
82Increased nuchal translucency (HP:0010880)1.97277279
83Clubbing of toes (HP:0100760)1.96873100
84Duplicated collecting system (HP:0000081)1.96280147
85Aplastic anemia (HP:0001915)1.95386534
86Atrophy/Degeneration involving motor neurons (HP:0007373)1.94947143
87Premature graying of hair (HP:0002216)1.94254688
88Glioma (HP:0009733)1.93393836
89Aplasia/Hypoplasia of the sternum (HP:0006714)1.92887303
90Absent epiphyses (HP:0010577)1.91847013
91Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.91847013
92Volvulus (HP:0002580)1.91802344
93Neoplasm of the oral cavity (HP:0100649)1.91287133
94Pancytopenia (HP:0001876)1.90524186
95Ankle contracture (HP:0006466)1.88675935
96Abnormal lung lobation (HP:0002101)1.88431576
97Short humerus (HP:0005792)1.88269893
98Acute myeloid leukemia (HP:0004808)1.87715662
99Lipid accumulation in hepatocytes (HP:0006561)1.87583239
100Abnormality of the proximal phalanges of the hand (HP:0009834)1.87256477
101Shawl scrotum (HP:0000049)1.86863904
102Microretrognathia (HP:0000308)1.86219345
103Absent septum pellucidum (HP:0001331)1.85624001
104Slender long bone (HP:0003100)1.85452551
105Aplasia/Hypoplasia of the earlobes (HP:0009906)1.85430004
106Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.85179357
107Abnormality of alanine metabolism (HP:0010916)1.85179357
108Hyperalaninemia (HP:0003348)1.85179357
109Embryonal renal neoplasm (HP:0011794)1.84223370
110Abnormality of the septum pellucidum (HP:0007375)1.83098306
111Azoospermia (HP:0000027)1.82630837
112Abnormality of methionine metabolism (HP:0010901)1.82493919
113Multiple enchondromatosis (HP:0005701)1.82085603
114Pelvic girdle muscle weakness (HP:0003749)1.81550671
115Abnormality of glycolysis (HP:0004366)1.80801238
116Abnormality of the renal collecting system (HP:0004742)1.80620669
117Breast carcinoma (HP:0003002)1.78581084
118High pitched voice (HP:0001620)1.78129257
119Neoplasm of the adrenal gland (HP:0100631)1.77130747
120Choanal atresia (HP:0000453)1.77117372
121Arteriovenous malformation (HP:0100026)1.76424938
122Abnormal number of incisors (HP:0011064)1.75534135
123Short middle phalanx of the 5th finger (HP:0004220)1.75174119
124Overlapping toe (HP:0001845)1.73746046
125Septo-optic dysplasia (HP:0100842)1.72871363
126Neoplasm of the adrenal cortex (HP:0100641)1.72031002
127Abnormality of serum amino acid levels (HP:0003112)1.71257506
128Acute encephalopathy (HP:0006846)1.70943388
129Ovarian neoplasm (HP:0100615)1.70117539
130Abnormality of cochlea (HP:0000375)1.69141380
131Increased serum lactate (HP:0002151)1.69131778
132Neoplasm of striated muscle (HP:0009728)1.69055129
133Hyperglycinuria (HP:0003108)1.66398588
134Cleft eyelid (HP:0000625)1.66112782
135Hyperglycinemia (HP:0002154)1.65117819
136Hypoplastic pelvis (HP:0008839)1.65024452
137Type I transferrin isoform profile (HP:0003642)1.63773154
138Increased CSF lactate (HP:0002490)1.63125837
139Megaloblastic anemia (HP:0001889)1.61709390
140Abnormality of DNA repair (HP:0003254)1.60433927
141Small hand (HP:0200055)1.59573688
142Abdominal situs inversus (HP:0003363)1.59553791
143Abnormality of abdominal situs (HP:0011620)1.59553791
144Preaxial hand polydactyly (HP:0001177)1.55729169
145Uterine neoplasm (HP:0010784)1.55231139

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.74956527
2WEE14.24364296
3CDC74.11559055
4NEK23.84778515
5EIF2AK13.16723243
6PLK43.16326549
7TTK3.02314251
8PBK2.66163493
9BRSK22.49331266
10ACVR1B2.40443582
11PLK12.37112330
12NEK12.34914101
13SRPK12.25333503
14MST42.17094822
15VRK22.13319425
16CDK122.11142746
17CHEK21.94376306
18PLK31.86787326
19DYRK31.84404246
20TAF11.82733847
21PDK31.79163332
22PDK41.79163332
23AURKB1.78183781
24TRIM281.74021961
25STK31.67460136
26NUAK11.59010563
27EPHA21.58898635
28LATS21.51697699
29ATR1.51119308
30BRSK11.50732878
31TSSK61.48638092
32CDK71.45939784
33MKNK11.43288210
34LATS11.42361537
35CHEK11.40593327
36EIF2AK31.39483410
37CDK41.38461873
38MKNK21.37443754
39STK38L1.36885447
40TESK21.33290648
41NME21.32008335
42MAP3K81.31797832
43STK101.23538246
44EEF2K1.22530182
45RPS6KA41.21402924
46AURKA1.18333121
47BMPR1B1.15795195
48RPS6KB21.15450325
49ZAK1.15082068
50BRAF1.14472233
51STK41.12213150
52MELK1.10526965
53VRK11.07267061
54AKT31.07239600
55CCNB11.05071208
56PDK21.05007417
57ATM1.03081307
58NME10.98833624
59TLK10.90418203
60CDK20.88999804
61WNK30.86921163
62TESK10.86743840
63PIM10.86545933
64PASK0.85120140
65SCYL20.84376648
66CDK60.82796669
67PNCK0.76485327
68BRD40.73546378
69CDK10.72260700
70PAK10.68664421
71STK160.67372046
72PLK20.63385600
73CLK10.61791608
74PAK40.61545714
75ALK0.58908601
76EIF2AK20.56794498
77MTOR0.56434859
78CDK80.50361204
79PRKCI0.49740413
80CSNK1G10.49166271
81DYRK20.48358741
82TNIK0.46702705
83CSNK2A20.45410775
84CSNK2A10.44810362
85STK390.43352053
86RAF10.43154504
87PIM20.42491968
88MAPKAPK50.42391793
89BCR0.39992992
90SMG10.39082484
91MAP3K50.37654190
92ERBB30.37503338
93WNK40.36940846
94PAK20.36398204
95YES10.35639958
96MAP3K100.35300527
97CSNK1E0.34625993
98RPS6KA50.34275963
99MARK30.33947790
100ERBB40.33768310
101CDK190.32804933
102MAPKAPK30.32287720
103CSNK1G20.31785713
104TGFBR10.31514304
105PRKDC0.30556405
106MET0.30550199
107MAP3K60.29006391
108MST1R0.27563166
109NEK90.26801861
110CSNK1D0.26474394
111CDK90.24962877
112DAPK10.24571792
113MAPK140.23626217
114CDK180.23043596
115PRKAA10.21306347
116GSK3B0.20039472
117CDK140.19840463
118CDK11A0.19790063
119CDK150.19722165
120CSNK1A1L0.19679546
121MAP3K90.18983998
122AKT20.18557291
123KSR10.18151368
124MAPK10.17859891
125CHUK0.17216081
126TAOK10.16038545
127MAPK100.16002801
128AKT10.14179992
129CDK30.13332227
130CSNK1G30.13145856
131STK240.13088867

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.19833540
2DNA replication_Homo sapiens_hsa030304.09043008
3RNA transport_Homo sapiens_hsa030133.61299599
4Cell cycle_Homo sapiens_hsa041103.53030255
5Mismatch repair_Homo sapiens_hsa034303.50042259
6RNA polymerase_Homo sapiens_hsa030203.44310209
7Vitamin B6 metabolism_Homo sapiens_hsa007503.40486442
8Homologous recombination_Homo sapiens_hsa034403.00628863
9Spliceosome_Homo sapiens_hsa030402.85678051
10Fanconi anemia pathway_Homo sapiens_hsa034602.74367745
11Basal transcription factors_Homo sapiens_hsa030222.73451586
12Nucleotide excision repair_Homo sapiens_hsa034202.55208003
13Base excision repair_Homo sapiens_hsa034102.53708109
14p53 signaling pathway_Homo sapiens_hsa041152.41261850
15Pyrimidine metabolism_Homo sapiens_hsa002402.31484909
16Proteasome_Homo sapiens_hsa030502.14258384
17One carbon pool by folate_Homo sapiens_hsa006702.12298916
18RNA degradation_Homo sapiens_hsa030181.96872863
19mRNA surveillance pathway_Homo sapiens_hsa030151.96681439
20Non-homologous end-joining_Homo sapiens_hsa034501.93216935
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.85594082
22Protein export_Homo sapiens_hsa030601.60478091
23Ribosome_Homo sapiens_hsa030101.57874492
24Oocyte meiosis_Homo sapiens_hsa041141.57665016
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.52165390
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.39204655
27Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.39015461
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.38857322
29Purine metabolism_Homo sapiens_hsa002301.38116759
30Propanoate metabolism_Homo sapiens_hsa006401.29354603
31Epstein-Barr virus infection_Homo sapiens_hsa051691.28759131
32Systemic lupus erythematosus_Homo sapiens_hsa053221.20035191
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15735547
34Pyruvate metabolism_Homo sapiens_hsa006201.13977792
35Viral carcinogenesis_Homo sapiens_hsa052031.13045039
36Pentose phosphate pathway_Homo sapiens_hsa000301.09867730
37Steroid biosynthesis_Homo sapiens_hsa001001.08968054
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.07681686
392-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.07339282
40Fatty acid elongation_Homo sapiens_hsa000621.06524560
41Folate biosynthesis_Homo sapiens_hsa007901.05272070
42Parkinsons disease_Homo sapiens_hsa050120.97524856
43Herpes simplex infection_Homo sapiens_hsa051680.95845694
44MicroRNAs in cancer_Homo sapiens_hsa052060.92619527
45Huntingtons disease_Homo sapiens_hsa050160.89468743
46Biosynthesis of amino acids_Homo sapiens_hsa012300.89175111
47Small cell lung cancer_Homo sapiens_hsa052220.88187263
48Oxidative phosphorylation_Homo sapiens_hsa001900.83594109
49Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.83027722
50Selenocompound metabolism_Homo sapiens_hsa004500.81696066
51Antigen processing and presentation_Homo sapiens_hsa046120.81148953
52HTLV-I infection_Homo sapiens_hsa051660.79837547
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.77597029
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.75769883
55Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.74675652
56TGF-beta signaling pathway_Homo sapiens_hsa043500.67548577
57Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.66880707
58Hippo signaling pathway_Homo sapiens_hsa043900.66588277
59Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.66112489
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.65382975
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.55842730
62Vitamin digestion and absorption_Homo sapiens_hsa049770.53949718
63Thyroid cancer_Homo sapiens_hsa052160.51609462
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.50944724
65Regulation of autophagy_Homo sapiens_hsa041400.49172955
66Glycerophospholipid metabolism_Homo sapiens_hsa005640.49066266
67mTOR signaling pathway_Homo sapiens_hsa041500.47780110
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.46219445
69Metabolic pathways_Homo sapiens_hsa011000.45867878
70Apoptosis_Homo sapiens_hsa042100.43484315
71Fatty acid metabolism_Homo sapiens_hsa012120.43333728
72Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42961130
73Colorectal cancer_Homo sapiens_hsa052100.42364377
74N-Glycan biosynthesis_Homo sapiens_hsa005100.42151510
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41498884
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41306410
77Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40432175
78Hepatitis B_Homo sapiens_hsa051610.40047680
79Glutathione metabolism_Homo sapiens_hsa004800.39702383
80Sulfur relay system_Homo sapiens_hsa041220.39347913
81Alzheimers disease_Homo sapiens_hsa050100.38870781
82FoxO signaling pathway_Homo sapiens_hsa040680.38676435
83Adherens junction_Homo sapiens_hsa045200.37414965
84Basal cell carcinoma_Homo sapiens_hsa052170.36293677
85Linoleic acid metabolism_Homo sapiens_hsa005910.35421958
86Bladder cancer_Homo sapiens_hsa052190.35293915
87Legionellosis_Homo sapiens_hsa051340.35138226
88Hedgehog signaling pathway_Homo sapiens_hsa043400.34735183
89Chronic myeloid leukemia_Homo sapiens_hsa052200.33049815
90Alcoholism_Homo sapiens_hsa050340.32090864
91Prostate cancer_Homo sapiens_hsa052150.31419112
92Notch signaling pathway_Homo sapiens_hsa043300.29407897
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.28380114
94HIF-1 signaling pathway_Homo sapiens_hsa040660.28203808
95Pathways in cancer_Homo sapiens_hsa052000.27185144
96Carbon metabolism_Homo sapiens_hsa012000.27077738
97Measles_Homo sapiens_hsa051620.26493163
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.26480658
99Pancreatic cancer_Homo sapiens_hsa052120.26449460
100Influenza A_Homo sapiens_hsa051640.25730075
101alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25722860
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25130788
103Cyanoamino acid metabolism_Homo sapiens_hsa004600.25025114
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.23646905
105Shigellosis_Homo sapiens_hsa051310.23366037
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.21390270
107Sulfur metabolism_Homo sapiens_hsa009200.20392607
108Renin-angiotensin system_Homo sapiens_hsa046140.20024485
109Tight junction_Homo sapiens_hsa045300.19439344
110Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.19325021
111Butanoate metabolism_Homo sapiens_hsa006500.18402301
112Caffeine metabolism_Homo sapiens_hsa002320.17761455
113Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.17757420
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.17671361
115Dorso-ventral axis formation_Homo sapiens_hsa043200.17311763
116Viral myocarditis_Homo sapiens_hsa054160.16899912
117Fructose and mannose metabolism_Homo sapiens_hsa000510.16310993
118Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.16241360
119Longevity regulating pathway - mammal_Homo sapiens_hsa042110.15728257
120NOD-like receptor signaling pathway_Homo sapiens_hsa046210.15614378
121Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.15585629
122Phototransduction_Homo sapiens_hsa047440.15040735
123Fatty acid degradation_Homo sapiens_hsa000710.14778189
124beta-Alanine metabolism_Homo sapiens_hsa004100.14436405
125Wnt signaling pathway_Homo sapiens_hsa043100.13459658
126Circadian rhythm_Homo sapiens_hsa047100.13245929
127Arginine and proline metabolism_Homo sapiens_hsa003300.12904000
128Tryptophan metabolism_Homo sapiens_hsa003800.12531411
129Intestinal immune network for IgA production_Homo sapiens_hsa046720.11951630
130Pentose and glucuronate interconversions_Homo sapiens_hsa000400.11630982
131Lysine degradation_Homo sapiens_hsa003100.11387964
132Endometrial cancer_Homo sapiens_hsa052130.10310114
133Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.10272203
134Peroxisome_Homo sapiens_hsa041460.09754219
135Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.04740975

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