DDX55P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1dopamine transport (GO:0015872)5.89661395
2dopamine biosynthetic process (GO:0042416)5.31570839
3intestinal epithelial cell development (GO:0060576)5.21105710
4protein polyglutamylation (GO:0018095)5.16598206
5serotonin metabolic process (GO:0042428)4.97146001
6chondrocyte proliferation (GO:0035988)4.88387861
7norepinephrine metabolic process (GO:0042415)4.82411100
8primary amino compound metabolic process (GO:1901160)4.76305087
9oligosaccharide catabolic process (GO:0009313)4.41338871
10regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.31703954
11catecholamine transport (GO:0051937)4.25021513
12positive regulation of cardiac muscle cell differentiation (GO:2000727)4.23602436
13fucose catabolic process (GO:0019317)4.07103500
14L-fucose metabolic process (GO:0042354)4.07103500
15L-fucose catabolic process (GO:0042355)4.07103500
16catechol-containing compound biosynthetic process (GO:0009713)3.99567671
17catecholamine biosynthetic process (GO:0042423)3.99567671
18regulation of acyl-CoA biosynthetic process (GO:0050812)3.98690954
19establishment of protein localization to mitochondrial membrane (GO:0090151)3.75813541
20dendritic spine morphogenesis (GO:0060997)3.74978586
21auditory receptor cell differentiation (GO:0042491)3.55699544
22snRNA transcription (GO:0009301)3.47589030
23regulation of cofactor metabolic process (GO:0051193)3.37122272
24regulation of coenzyme metabolic process (GO:0051196)3.37122272
25regulation of neurotransmitter uptake (GO:0051580)3.36922794
26UDP-N-acetylglucosamine metabolic process (GO:0006047)3.35100533
27DNA double-strand break processing (GO:0000729)3.28534093
28positive regulation of calcium ion import (GO:0090280)3.27997372
29regulation of catecholamine metabolic process (GO:0042069)3.18579903
30regulation of dopamine metabolic process (GO:0042053)3.18579903
31atrial cardiac muscle cell action potential (GO:0086014)3.18218027
32indole-containing compound metabolic process (GO:0042430)3.17668997
33monoubiquitinated protein deubiquitination (GO:0035520)3.14849600
34dopamine metabolic process (GO:0042417)3.13524055
35dentate gyrus development (GO:0021542)3.11585391
36regulation of sulfur metabolic process (GO:0042762)3.09192258
37positive regulation of cell fate commitment (GO:0010455)3.04371781
38positive regulation of dendritic spine morphogenesis (GO:0061003)3.04350438
39ether lipid metabolic process (GO:0046485)2.99464683
40regulation of cardiac muscle cell contraction (GO:0086004)2.97961264
41ceramide catabolic process (GO:0046514)2.96415053
42behavioral response to nicotine (GO:0035095)2.95313042
43epithelial cell fate commitment (GO:0072148)2.94582338
44glycosphingolipid catabolic process (GO:0046479)2.91404455
45mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.87349260
46synaptic transmission, dopaminergic (GO:0001963)2.87299834
47tryptophan metabolic process (GO:0006568)2.86241281
48phenol-containing compound catabolic process (GO:0019336)2.85487025
49negative regulation of hormone biosynthetic process (GO:0032353)2.82878465
50monoamine transport (GO:0015844)2.82780192
51ganglioside metabolic process (GO:0001573)2.77613416
52heart field specification (GO:0003128)2.76780002
53secondary heart field specification (GO:0003139)2.76780002
54endothelial tube morphogenesis (GO:0061154)2.75257251
55morphogenesis of an endothelium (GO:0003159)2.75257251
56prepulse inhibition (GO:0060134)2.74322858
57T-helper cell differentiation (GO:0042093)2.73928468
58CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.73928468
59glycosphingolipid biosynthetic process (GO:0006688)2.72549221
60negative regulation of signal transduction by p53 class mediator (GO:1901797)2.72157976
61cellular response to nicotine (GO:0071316)2.69868111
62intracellular protein transmembrane import (GO:0044743)2.69792821
63positive regulation of cell size (GO:0045793)2.69706750
64cardiac left ventricle morphogenesis (GO:0003214)2.69141122
65indolalkylamine metabolic process (GO:0006586)2.68992714
66regulation of oxidative phosphorylation (GO:0002082)2.64814777
67insulin secretion (GO:0030073)2.62531636
68response to amphetamine (GO:0001975)2.62268048
69signal peptide processing (GO:0006465)2.62266194
70glycolipid catabolic process (GO:0019377)2.61433182
71calcium ion-dependent exocytosis (GO:0017156)2.60615141
72protein K11-linked deubiquitination (GO:0035871)2.60521183
73positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.60516671
74regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.60191626
75regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.60191626
76positive regulation of sodium ion transmembrane transporter activity (GO:2000651)2.59398523
77regulation of Rac protein signal transduction (GO:0035020)2.53334542
78peptidyl-histidine modification (GO:0018202)2.52333597
79innervation (GO:0060384)2.51634807
80opioid receptor signaling pathway (GO:0038003)2.51398815
81regulation of mesoderm development (GO:2000380)2.49984867
82regulation of cardiac muscle cell differentiation (GO:2000725)2.49907288
83male meiosis I (GO:0007141)2.47334175
84anterograde synaptic vesicle transport (GO:0048490)2.47234113
85peptide hormone processing (GO:0016486)2.46938276
86regulation of protein polyubiquitination (GO:1902914)2.46605232
87peptidyl-glutamic acid modification (GO:0018200)2.46107101
88neuronal action potential (GO:0019228)2.45751163
89ether metabolic process (GO:0018904)2.45559196
90glycerophospholipid catabolic process (GO:0046475)2.44913682
91alpha-beta T cell activation involved in immune response (GO:0002287)2.44501917
92T cell differentiation involved in immune response (GO:0002292)2.44501917
93alpha-beta T cell differentiation involved in immune response (GO:0002293)2.44501917
94multicellular organismal aging (GO:0010259)2.43938594
95catechol-containing compound metabolic process (GO:0009712)2.39748688
96catecholamine metabolic process (GO:0006584)2.39748688
97specification of organ identity (GO:0010092)2.39229740
98positive regulation of protein depolymerization (GO:1901881)2.38524493
99negative regulation of execution phase of apoptosis (GO:1900118)2.38014793
100regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.37878613

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse7.00817303
2GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse4.38114604
3EZH2_22144423_ChIP-Seq_EOC_Human3.34839640
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.02312843
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.71518809
6GBX2_23144817_ChIP-Seq_PC3_Human2.54104996
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.48990228
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.46932622
9FUS_26573619_Chip-Seq_HEK293_Human2.43122515
10GATA1_22025678_ChIP-Seq_K562_Human2.21618450
11TAF15_26573619_Chip-Seq_HEK293_Human2.19441748
12P300_19829295_ChIP-Seq_ESCs_Human2.16938573
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.07198724
14SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.96332706
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.88646112
16CTBP1_25329375_ChIP-Seq_LNCAP_Human1.85787806
17AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.83677446
18ELK1_19687146_ChIP-ChIP_HELA_Human1.81689553
19EWS_26573619_Chip-Seq_HEK293_Human1.81627875
20SMAD3_21741376_ChIP-Seq_EPCs_Human1.78264801
21KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.75369903
22SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.73393552
23NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.72096111
24SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.71763799
25SMAD4_21799915_ChIP-Seq_A2780_Human1.70007687
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68190725
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.66306322
28VDR_22108803_ChIP-Seq_LS180_Human1.66305671
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.65940833
30STAT3_23295773_ChIP-Seq_U87_Human1.61425511
31BCAT_22108803_ChIP-Seq_LS180_Human1.58343412
32TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57944049
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54655680
34TRIM28_21343339_ChIP-Seq_HEK293_Human1.53656586
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.50592290
36NANOG_19829295_ChIP-Seq_ESCs_Human1.48637291
37SOX2_19829295_ChIP-Seq_ESCs_Human1.48637291
38HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.48322534
39NANOG_18555785_Chip-Seq_ESCs_Mouse1.46550841
40UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46039558
41TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42350970
42CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42171469
43KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.41345038
44REST_21632747_ChIP-Seq_MESCs_Mouse1.38985080
45TP53_22573176_ChIP-Seq_HFKS_Human1.38460756
46OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35992335
47IGF1R_20145208_ChIP-Seq_DFB_Human1.34764807
48NR3C1_21868756_ChIP-Seq_MCF10A_Human1.32437505
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.32409899
50TCF4_22108803_ChIP-Seq_LS180_Human1.31783872
51EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.29358860
52EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.29181003
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.28049226
54FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.27434454
55BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26617474
56JUN_21703547_ChIP-Seq_K562_Human1.26155401
57IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25851273
58CBP_20019798_ChIP-Seq_JUKART_Human1.25851273
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.25378477
60CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.24700785
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.23571375
62CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23109148
63FLI1_21867929_ChIP-Seq_TH2_Mouse1.23038226
64SMAD_19615063_ChIP-ChIP_OVARY_Human1.22449237
65MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20382035
66AHR_22903824_ChIP-Seq_MCF-7_Human1.19847920
67TCF4_23295773_ChIP-Seq_U87_Human1.19513519
68RNF2_27304074_Chip-Seq_NSC_Mouse1.18645713
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.18298327
70EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18169217
71AR_25329375_ChIP-Seq_VCAP_Human1.17730504
72RUNX2_22187159_ChIP-Seq_PCA_Human1.14380904
73TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08992276
74POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08992276
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08643940
76PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.08300439
77TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.07233010
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.06799692
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06352173
80TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05028819
81TAL1_26923725_Chip-Seq_HPCs_Mouse1.04395057
82LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04265284
83WT1_19549856_ChIP-ChIP_CCG9911_Human1.04061633
84CBX2_27304074_Chip-Seq_ESCs_Mouse1.03960396
85SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.03529724
86TP53_18474530_ChIP-ChIP_U2OS_Human1.03417760
87PRDM14_20953172_ChIP-Seq_ESCs_Human1.02215968
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.01210822
89RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99923027
90ARNT_22903824_ChIP-Seq_MCF-7_Human0.98670528
91SMAD4_21741376_ChIP-Seq_EPCs_Human0.98464219
92AR_20517297_ChIP-Seq_VCAP_Human0.98070357
93KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97592426
94P53_22387025_ChIP-Seq_ESCs_Mouse0.97471766
95ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.97443240
96KDM2B_26808549_Chip-Seq_REH_Human0.97089775
97FOXA1_25329375_ChIP-Seq_VCAP_Human0.96207821
98FOXA1_27270436_Chip-Seq_PROSTATE_Human0.96207821
99ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93879166
100SUZ12_27294783_Chip-Seq_NPCs_Mouse0.93672345

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006054_spinal_hemorrhage3.82666708
2MP0002163_abnormal_gland_morphology3.12372859
3MP0010386_abnormal_urinary_bladder3.04744163
4MP0000372_irregular_coat_pigmentation2.83655749
5MP0005379_endocrine/exocrine_gland_phen2.79694301
6MP0006292_abnormal_olfactory_placode2.70564473
7MP0002638_abnormal_pupillary_reflex2.67365964
8MP0002837_dystrophic_cardiac_calcinosis2.63826474
9MP0000566_synostosis2.49739042
10MP0009046_muscle_twitch2.43003061
11MP0006072_abnormal_retinal_apoptosis2.39429130
12MP0005377_hearing/vestibular/ear_phenot2.33608191
13MP0003878_abnormal_ear_physiology2.33608191
14MP0008057_abnormal_DNA_replication2.14495025
15MP0009745_abnormal_behavioral_response2.02477652
16MP0002938_white_spotting2.01927719
17MP0003787_abnormal_imprinting1.95024967
18MP0001905_abnormal_dopamine_level1.94181645
19MP0005645_abnormal_hypothalamus_physiol1.88843601
20MP0005084_abnormal_gallbladder_morpholo1.84992331
21MP0003937_abnormal_limbs/digits/tail_de1.80819958
22MP0003122_maternal_imprinting1.80440830
23MP0003195_calcinosis1.76765185
24MP0008877_abnormal_DNA_methylation1.71738807
25MP0000631_abnormal_neuroendocrine_gland1.70146216
26MP0008875_abnormal_xenobiotic_pharmacok1.68671499
27MP0001501_abnormal_sleep_pattern1.68053712
28MP0004270_analgesia1.67921985
29MP0001968_abnormal_touch/_nociception1.65495625
30MP0002909_abnormal_adrenal_gland1.62145002
31MP0002272_abnormal_nervous_system1.62130807
32MP0004885_abnormal_endolymph1.61326417
33MP0006276_abnormal_autonomic_nervous1.59712867
34MP0003567_abnormal_fetal_cardiomyocyte1.57715992
35MP0002876_abnormal_thyroid_physiology1.56341101
36MP0001502_abnormal_circadian_rhythm1.55650385
37MP0008872_abnormal_physiological_respon1.55262055
38MP0003121_genomic_imprinting1.53795401
39MP0001879_abnormal_lymphatic_vessel1.53407846
40MP0005253_abnormal_eye_physiology1.48845777
41MP0005310_abnormal_salivary_gland1.46561888
42MP0002064_seizures1.46201726
43MP0002735_abnormal_chemical_nociception1.45870554
44MP0005623_abnormal_meninges_morphology1.45613218
45MP0009780_abnormal_chondrocyte_physiolo1.44616030
46MP0002009_preneoplasia1.38925976
47MP0000778_abnormal_nervous_system1.37099386
48MP0000003_abnormal_adipose_tissue1.35256506
49MP0005187_abnormal_penis_morphology1.32989791
50MP0005646_abnormal_pituitary_gland1.29386348
51MP0010368_abnormal_lymphatic_system1.28411762
52MP0005551_abnormal_eye_electrophysiolog1.28142649
53MP0000639_abnormal_adrenal_gland1.26847795
54MP0004043_abnormal_pH_regulation1.23975376
55MP0002168_other_aberrant_phenotype1.19849944
56MP0000613_abnormal_salivary_gland1.19592477
57MP0001485_abnormal_pinna_reflex1.19373659
58MP0005332_abnormal_amino_acid1.17587435
59MP0003868_abnormal_feces_composition1.17109394
60MP0009697_abnormal_copulation1.15243775
61MP0004742_abnormal_vestibular_system1.15022540
62MP0003137_abnormal_impulse_conducting1.11365076
63MP0003635_abnormal_synaptic_transmissio1.09185637
64MP0005367_renal/urinary_system_phenotyp1.08305496
65MP0000516_abnormal_urinary_system1.08305496
66MP0002557_abnormal_social/conspecific_i1.07440210
67MP0002572_abnormal_emotion/affect_behav1.03726273
68MP0005448_abnormal_energy_balance1.03146245
69MP0002067_abnormal_sensory_capabilities1.00813476
70MP0001944_abnormal_pancreas_morphology0.99711424
71MP0004142_abnormal_muscle_tone0.96925692
72MP0004215_abnormal_myocardial_fiber0.94750329
73MP0005395_other_phenotype0.94346381
74MP0005248_abnormal_Harderian_gland0.92979622
75MP0005171_absent_coat_pigmentation0.92876994
76MP0002069_abnormal_eating/drinking_beha0.92647804
77MP0002063_abnormal_learning/memory/cond0.91618145
78MP0003385_abnormal_body_wall0.89455115
79MP0002736_abnormal_nociception_after0.88441437
80MP0005174_abnormal_tail_pigmentation0.87754927
81MP0002090_abnormal_vision0.87136912
82MP0002733_abnormal_thermal_nociception0.85790248
83MP0000538_abnormal_urinary_bladder0.83478066
84MP0001486_abnormal_startle_reflex0.82360130
85MP0000026_abnormal_inner_ear0.82210214
86MP0002734_abnormal_mechanical_nocicepti0.80806704
87MP0002693_abnormal_pancreas_physiology0.78405386
88MP0000013_abnormal_adipose_tissue0.78151996
89MP0001970_abnormal_pain_threshold0.77571173
90MP0002229_neurodegeneration0.77392119
91MP0001348_abnormal_lacrimal_gland0.76467052
92MP0003718_maternal_effect0.75332258
93MP0005636_abnormal_mineral_homeostasis0.73159495
94MP0001440_abnormal_grooming_behavior0.72134612
95MP0003880_abnormal_central_pattern0.71660994
96MP0002295_abnormal_pulmonary_circulatio0.70497989
97MP0002882_abnormal_neuron_morphology0.69447606
98MP0005083_abnormal_biliary_tract0.67643875
99MP0001963_abnormal_hearing_physiology0.66404061
100MP0001756_abnormal_urination0.65435023

Predicted human phenotypes

RankGene SetZ-score
1Agitation (HP:0000713)5.21579754
2Limb dystonia (HP:0002451)4.60170760
3Genetic anticipation (HP:0003743)4.34362446
4Progressive cerebellar ataxia (HP:0002073)4.21130898
5Hypothermia (HP:0002045)4.00638515
6Failure to thrive in infancy (HP:0001531)3.97882407
7Hypokinesia (HP:0002375)3.86771128
8Proximal tubulopathy (HP:0000114)3.49019904
9Pancreatic islet-cell hyperplasia (HP:0004510)3.48960531
10Abnormality of midbrain morphology (HP:0002418)3.44471049
11Molar tooth sign on MRI (HP:0002419)3.44471049
12Urethral obstruction (HP:0000796)3.26015538
13Febrile seizures (HP:0002373)3.23622633
14Drooling (HP:0002307)3.20483462
15Thyroiditis (HP:0100646)3.17439235
16Nephronophthisis (HP:0000090)3.10830029
17Restlessness (HP:0000711)3.07866787
18Volvulus (HP:0002580)3.03716430
19Severe visual impairment (HP:0001141)3.01684776
20Atonic seizures (HP:0010819)2.97439887
21Excessive salivation (HP:0003781)2.95660030
22Decreased muscle mass (HP:0003199)2.94428987
23Gaze-evoked nystagmus (HP:0000640)2.90656555
24Diminished movement (HP:0002374)2.88361847
25Limb hypertonia (HP:0002509)2.85573396
26Delayed gross motor development (HP:0002194)2.83307997
27Abnormality of aromatic amino acid family metabolism (HP:0004338)2.80261153
28Ectopic kidney (HP:0000086)2.76421800
29Chronic diarrhea (HP:0002028)2.75649210
30Postural tremor (HP:0002174)2.74992620
31Congenital stationary night blindness (HP:0007642)2.69200514
32Severe combined immunodeficiency (HP:0004430)2.61040565
33Acute necrotizing encephalopathy (HP:0006965)2.58738235
34Long nose (HP:0003189)2.57136350
35Dyskinesia (HP:0100660)2.47130337
36Abnormality of the renal medulla (HP:0100957)2.44917138
37Bony spicule pigmentary retinopathy (HP:0007737)2.43876237
38Dialeptic seizures (HP:0011146)2.35456762
39Progressive neurologic deterioration (HP:0002344)2.33142054
40Colon cancer (HP:0003003)2.32526355
41EEG with generalized epileptiform discharges (HP:0011198)2.31827567
42Absence seizures (HP:0002121)2.31615771
43Epileptiform EEG discharges (HP:0011182)2.30646778
44Intestinal atresia (HP:0011100)2.29882897
45Hyperglycemia (HP:0003074)2.29241914
46Hypsarrhythmia (HP:0002521)2.26546822
47Hypoproteinemia (HP:0003075)2.25686925
48B lymphocytopenia (HP:0010976)2.24501511
49Action tremor (HP:0002345)2.21770284
50Progressive macrocephaly (HP:0004481)2.21484232
51Constricted visual fields (HP:0001133)2.20843255
52Pendular nystagmus (HP:0012043)2.19443466
53Abnormal mitochondria in muscle tissue (HP:0008316)2.18428031
54Abnormality of salivation (HP:0100755)2.17752263
55Adrenal hypoplasia (HP:0000835)2.15829346
56Acute encephalopathy (HP:0006846)2.13699111
57Prolonged partial thromboplastin time (HP:0003645)2.12897244
58Large for gestational age (HP:0001520)2.06571374
59Akinesia (HP:0002304)2.06506666
60Broad-based gait (HP:0002136)2.05739864
61Oligodactyly (hands) (HP:0001180)2.01410835
62Nonimmune hydrops fetalis (HP:0001790)2.00775737
63Morphological abnormality of the pyramidal tract (HP:0002062)1.99965498
64Curly hair (HP:0002212)1.99555716
65Hypoalbuminemia (HP:0003073)1.99003018
66Abnormal albumin level (HP:0012116)1.99003018
67Abnormality of macular pigmentation (HP:0008002)1.97796998
68Humeroradial synostosis (HP:0003041)1.96402154
69Synostosis involving the elbow (HP:0003938)1.96402154
702-3 toe syndactyly (HP:0004691)1.96131827
71Narrow forehead (HP:0000341)1.94978211
72Anxiety (HP:0000739)1.91843882
73Increased CSF lactate (HP:0002490)1.91829290
74Bradykinesia (HP:0002067)1.90768055
75Retinal dysplasia (HP:0007973)1.87075379
76Parakeratosis (HP:0001036)1.85121504
77Oligodactyly (HP:0012165)1.83824538
78Abnormality of B cell number (HP:0010975)1.82412251
79Epileptic encephalopathy (HP:0200134)1.80704456
80Flat face (HP:0012368)1.79932003
81Vaginal fistula (HP:0004320)1.79806828
82Vacuolated lymphocytes (HP:0001922)1.79258955
83Ketosis (HP:0001946)1.78125626
84Hypoplasia of the thymus (HP:0000778)1.77590092
85Abnormal respiratory epithelium morphology (HP:0012253)1.76711484
86Abnormal respiratory motile cilium morphology (HP:0005938)1.76711484
87Mitochondrial inheritance (HP:0001427)1.76684812
88Absent/shortened dynein arms (HP:0200106)1.76000327
89Dynein arm defect of respiratory motile cilia (HP:0012255)1.76000327
90Abnormality of the pancreatic islet cells (HP:0006476)1.75564351
91Abnormality of endocrine pancreas physiology (HP:0012093)1.75564351
92Partial duplication of thumb phalanx (HP:0009944)1.75229661
93Progressive microcephaly (HP:0000253)1.74527759
94Muscular hypotonia of the trunk (HP:0008936)1.71178566
95Insulin-resistant diabetes mellitus (HP:0000831)1.71156204
96Type II lissencephaly (HP:0007260)1.69803260
97Abnormality of dental color (HP:0011073)1.68117297
98Preaxial foot polydactyly (HP:0001841)1.64972083
99Abnormality of the intrinsic pathway (HP:0010989)1.64781592
100Decreased activity of mitochondrial respiratory chain (HP:0008972)1.64541414

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PAK35.72230476
2FRK2.83037393
3STK392.50609103
4BMPR1B2.28927296
5ACVR1B2.28341739
6MKNK22.26892012
7MAP4K22.21915253
8WNK42.06869071
9WNK32.04705134
10SRPK11.98249580
11INSRR1.97426560
12CASK1.94128021
13SCYL21.93058610
14NUAK11.91499809
15MAPK131.87826104
16DAPK21.85530774
17PINK11.76082698
18CSNK1G31.72203386
19CSNK1G11.68208815
20CSNK1G21.66262897
21PHKG11.55502425
22PHKG21.55502425
23BCKDK1.55401833
24MAP2K71.50671888
25TNIK1.49518620
26ADRBK21.49123130
27MINK11.48678598
28MST41.45473385
29EPHB21.33208476
30FGFR31.28091484
31PLK21.25230721
32GRK11.23227672
33LATS11.19635502
34TIE11.16861554
35PRKCG1.10860393
36TEC1.09389363
37FGFR21.08223667
38CSNK1A1L1.04174587
39PRKCE1.02521950
40STK161.02402370
41CAMK2A0.99691185
42OXSR10.94755769
43NTRK30.94577706
44PAK20.90988603
45CAMK2D0.90974938
46GRK50.90361074
47KSR10.89239220
48STK38L0.88007460
49TRIM280.87684106
50BCR0.85512503
51TESK10.84745988
52MAPKAPK50.82913020
53LIMK10.82712862
54MKNK10.82690354
55TGFBR10.77585103
56MAP3K120.76241290
57PAK60.75621434
58PKN10.75051256
59CSNK1A10.73852752
60PNCK0.73025504
61PRKCI0.72536960
62MAP3K90.72169005
63NLK0.72053389
64EPHA40.71641587
65FER0.71314394
66STK380.70376366
67RPS6KB10.69986754
68MAPKAPK30.68477494
69PRKG10.67800512
70CAMK2G0.67346099
71DYRK20.64727778
72BRSK20.63228992
73MARK10.62090048
74MAP3K40.61436700
75CAMK2B0.61283928
76TSSK60.57247358
77CAMKK20.55767961
78EIF2AK10.53616762
79EIF2AK30.52838545
80RPS6KB20.49766340
81NTRK20.49390653
82EGFR0.49369264
83PIK3CA0.49159749
84SGK10.45255522
85MAP2K60.44589766
86PIK3CG0.43209473
87NME10.42682209
88ADRBK10.42366963
89FGFR10.40022283
90TAOK10.38225298
91CSNK1D0.38208955
92DAPK10.35791384
93CDK180.35484548
94PRKD10.35206693
95IRAK10.32521849
96MAP3K20.31754171
97PRKCQ0.31695735
98ABL20.30412398
99PRKACB0.28725598
100DYRK1A0.28076902

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009204.00958081
2Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.64338231
3Insulin secretion_Homo sapiens_hsa049112.59309159
4Oxidative phosphorylation_Homo sapiens_hsa001902.56584739
5Sphingolipid metabolism_Homo sapiens_hsa006002.31590758
6Parkinsons disease_Homo sapiens_hsa050122.18426553
7Folate biosynthesis_Homo sapiens_hsa007902.18242124
8Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.15906074
9Protein export_Homo sapiens_hsa030602.11891652
10Phototransduction_Homo sapiens_hsa047442.10105456
11Circadian rhythm_Homo sapiens_hsa047102.00277702
12Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.99356207
13SNARE interactions in vesicular transport_Homo sapiens_hsa041301.96758709
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.96601571
15Cocaine addiction_Homo sapiens_hsa050301.93393331
16Other glycan degradation_Homo sapiens_hsa005111.91104139
17Amphetamine addiction_Homo sapiens_hsa050311.90305667
18Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.89328990
19Nicotine addiction_Homo sapiens_hsa050331.87018061
20Propanoate metabolism_Homo sapiens_hsa006401.79789663
21Proteasome_Homo sapiens_hsa030501.71724996
22Ether lipid metabolism_Homo sapiens_hsa005651.70296551
23Synaptic vesicle cycle_Homo sapiens_hsa047211.69385627
24Non-homologous end-joining_Homo sapiens_hsa034501.55653538
25Morphine addiction_Homo sapiens_hsa050321.52951308
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.52006083
27Dopaminergic synapse_Homo sapiens_hsa047281.47257102
28Selenocompound metabolism_Homo sapiens_hsa004501.45295770
29Alzheimers disease_Homo sapiens_hsa050101.36088906
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.33011883
31Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.31601758
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.26151745
33Taste transduction_Homo sapiens_hsa047421.25522185
34Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.22083875
35Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.21900058
36Huntingtons disease_Homo sapiens_hsa050161.18170250
37Collecting duct acid secretion_Homo sapiens_hsa049661.17313390
38Circadian entrainment_Homo sapiens_hsa047131.14727405
39Olfactory transduction_Homo sapiens_hsa047401.12476713
40Maturity onset diabetes of the young_Homo sapiens_hsa049501.11283422
41RNA polymerase_Homo sapiens_hsa030201.09339264
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.08898131
43Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.07678499
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.05421520
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99369340
46Regulation of autophagy_Homo sapiens_hsa041400.96690924
47Tryptophan metabolism_Homo sapiens_hsa003800.95629226
48Serotonergic synapse_Homo sapiens_hsa047260.95294277
49Cardiac muscle contraction_Homo sapiens_hsa042600.93836045
50GABAergic synapse_Homo sapiens_hsa047270.92340569
51Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.90807123
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.89391615
53Nitrogen metabolism_Homo sapiens_hsa009100.88704781
54Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.88123077
55Primary bile acid biosynthesis_Homo sapiens_hsa001200.87843331
56beta-Alanine metabolism_Homo sapiens_hsa004100.87282552
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.85414021
58Pentose and glucuronate interconversions_Homo sapiens_hsa000400.84630024
59Cholinergic synapse_Homo sapiens_hsa047250.81898742
60RNA degradation_Homo sapiens_hsa030180.80738109
61Calcium signaling pathway_Homo sapiens_hsa040200.78187554
62Basal transcription factors_Homo sapiens_hsa030220.77459298
63Salivary secretion_Homo sapiens_hsa049700.75680025
64Thyroid hormone synthesis_Homo sapiens_hsa049180.74847033
65Fatty acid biosynthesis_Homo sapiens_hsa000610.73875488
66Butanoate metabolism_Homo sapiens_hsa006500.73417090
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71962312
68Aldosterone synthesis and secretion_Homo sapiens_hsa049250.69597457
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.68224961
70Vitamin B6 metabolism_Homo sapiens_hsa007500.66207734
71Hedgehog signaling pathway_Homo sapiens_hsa043400.66202773
72Glutamatergic synapse_Homo sapiens_hsa047240.63653334
73Pyruvate metabolism_Homo sapiens_hsa006200.62535814
74Gastric acid secretion_Homo sapiens_hsa049710.62332791
75Lysosome_Homo sapiens_hsa041420.60207817
76Metabolic pathways_Homo sapiens_hsa011000.56256560
77Peroxisome_Homo sapiens_hsa041460.52086703
78Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51924575
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49698711
80Linoleic acid metabolism_Homo sapiens_hsa005910.46311459
81Steroid hormone biosynthesis_Homo sapiens_hsa001400.44463119
82Hippo signaling pathway_Homo sapiens_hsa043900.43012613
83cAMP signaling pathway_Homo sapiens_hsa040240.42957844
84Glutathione metabolism_Homo sapiens_hsa004800.41397535
85Fatty acid metabolism_Homo sapiens_hsa012120.40011341
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.39550187
87Oocyte meiosis_Homo sapiens_hsa041140.38087050
88Retinol metabolism_Homo sapiens_hsa008300.35820186
89Glucagon signaling pathway_Homo sapiens_hsa049220.35372200
90Basal cell carcinoma_Homo sapiens_hsa052170.35289811
91TGF-beta signaling pathway_Homo sapiens_hsa043500.33818243
92Vibrio cholerae infection_Homo sapiens_hsa051100.33509415
93Mineral absorption_Homo sapiens_hsa049780.32809707
94Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.31108556
95Glycerolipid metabolism_Homo sapiens_hsa005610.30006437
96Pancreatic secretion_Homo sapiens_hsa049720.26754541
97Purine metabolism_Homo sapiens_hsa002300.26491198
98RNA transport_Homo sapiens_hsa030130.26151132
99Melanogenesis_Homo sapiens_hsa049160.26006586
100African trypanosomiasis_Homo sapiens_hsa051430.25144963

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »