DECR2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.32929310
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.32929310
3L-phenylalanine metabolic process (GO:0006558)6.97568042
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.97568042
5aromatic amino acid family catabolic process (GO:0009074)6.83565593
6indole-containing compound catabolic process (GO:0042436)6.38421243
7indolalkylamine catabolic process (GO:0046218)6.38421243
8tryptophan catabolic process (GO:0006569)6.38421243
9tryptophan metabolic process (GO:0006568)6.11076910
10triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.09458563
11kynurenine metabolic process (GO:0070189)5.97805265
12bile acid biosynthetic process (GO:0006699)5.78491579
13glyoxylate metabolic process (GO:0046487)5.53559879
14high-density lipoprotein particle remodeling (GO:0034375)5.53397684
15urea cycle (GO:0000050)5.47569230
16urea metabolic process (GO:0019627)5.47569230
17alpha-linolenic acid metabolic process (GO:0036109)5.30765406
18sulfur amino acid catabolic process (GO:0000098)5.13110030
19protein carboxylation (GO:0018214)5.09432230
20peptidyl-glutamic acid carboxylation (GO:0017187)5.09432230
21negative regulation of fibrinolysis (GO:0051918)5.07413905
22nitrogen cycle metabolic process (GO:0071941)5.03425732
23aromatic amino acid family metabolic process (GO:0009072)5.03424469
24regulation of fibrinolysis (GO:0051917)5.01377068
25serine family amino acid catabolic process (GO:0009071)4.99562021
26bile acid metabolic process (GO:0008206)4.99282430
27regulation of cholesterol esterification (GO:0010872)4.98134105
28cysteine metabolic process (GO:0006534)4.94909331
29complement activation, alternative pathway (GO:0006957)4.91067899
30homocysteine metabolic process (GO:0050667)4.88636661
31tyrosine metabolic process (GO:0006570)4.88060763
32fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.86724187
33regulation of protein activation cascade (GO:2000257)4.86534902
34reverse cholesterol transport (GO:0043691)4.82923395
35plasma lipoprotein particle remodeling (GO:0034369)4.76077085
36protein-lipid complex remodeling (GO:0034368)4.76077085
37macromolecular complex remodeling (GO:0034367)4.76077085
38regulation of triglyceride catabolic process (GO:0010896)4.72449066
39amino-acid betaine metabolic process (GO:0006577)4.67081977
40indolalkylamine metabolic process (GO:0006586)4.63681674
41alpha-amino acid catabolic process (GO:1901606)4.61325022
42amine catabolic process (GO:0009310)4.58834188
43cellular biogenic amine catabolic process (GO:0042402)4.58834188
44phospholipid efflux (GO:0033700)4.58502476
45epoxygenase P450 pathway (GO:0019373)4.53306972
46triglyceride homeostasis (GO:0070328)4.53150947
47acylglycerol homeostasis (GO:0055090)4.53150947
48regulation of complement activation (GO:0030449)4.52606319
49cellular ketone body metabolic process (GO:0046950)4.41532699
50bile acid and bile salt transport (GO:0015721)4.40761212
51lysine catabolic process (GO:0006554)4.38352511
52lysine metabolic process (GO:0006553)4.38352511
53imidazole-containing compound metabolic process (GO:0052803)4.33315173
54negative regulation of cholesterol transport (GO:0032375)4.31491156
55negative regulation of sterol transport (GO:0032372)4.31491156
56coenzyme catabolic process (GO:0009109)4.29692334
57cellular glucuronidation (GO:0052695)4.28361794
58cellular amino acid catabolic process (GO:0009063)4.23740927
59cholesterol efflux (GO:0033344)4.21023631
60benzene-containing compound metabolic process (GO:0042537)4.19441838
61low-density lipoprotein particle remodeling (GO:0034374)4.14394310
62oxidative demethylation (GO:0070989)4.14084799
63S-adenosylmethionine metabolic process (GO:0046500)4.11223594
64glycine metabolic process (GO:0006544)4.09813695
65drug metabolic process (GO:0017144)4.05097833
66plasma lipoprotein particle clearance (GO:0034381)4.04455738
67drug catabolic process (GO:0042737)4.02937894
68aldehyde catabolic process (GO:0046185)4.02761923
69NAD biosynthetic process (GO:0009435)3.99046722
70arginine metabolic process (GO:0006525)3.98712143
71glutamate metabolic process (GO:0006536)3.97648286
72serine family amino acid metabolic process (GO:0009069)3.92501233
73plasma lipoprotein particle assembly (GO:0034377)3.89864909
74glucuronate metabolic process (GO:0019585)3.86633308
75uronic acid metabolic process (GO:0006063)3.86633308
76regulation of plasminogen activation (GO:0010755)3.83815902
77very-low-density lipoprotein particle assembly (GO:0034379)3.81808966
78cellular modified amino acid catabolic process (GO:0042219)3.81671969
79arginine catabolic process (GO:0006527)3.81086929
80ketone body metabolic process (GO:1902224)3.80578864
81omega-hydroxylase P450 pathway (GO:0097267)3.79528764
82dicarboxylic acid biosynthetic process (GO:0043650)3.78546120
83organic acid catabolic process (GO:0016054)3.78294109
84carboxylic acid catabolic process (GO:0046395)3.78294109
85negative regulation of lipase activity (GO:0060192)3.77902464
86nicotinamide nucleotide biosynthetic process (GO:0019359)3.77518275
87pyridine nucleotide biosynthetic process (GO:0019363)3.77518275
88regulation of bile acid biosynthetic process (GO:0070857)3.77220917
89cofactor catabolic process (GO:0051187)3.75836869
90blood coagulation, intrinsic pathway (GO:0007597)3.73225470
91ethanol oxidation (GO:0006069)3.71253074
92phospholipid homeostasis (GO:0055091)3.71050066
93serine family amino acid biosynthetic process (GO:0009070)3.68828235
94fibrinolysis (GO:0042730)3.66117099
95positive regulation of triglyceride lipase activity (GO:0061365)3.64614235
96positive regulation of lipoprotein lipase activity (GO:0051006)3.64614235
97plasma lipoprotein particle organization (GO:0071827)3.63717544
98cholesterol homeostasis (GO:0042632)3.61261311
99positive regulation of lipid catabolic process (GO:0050996)3.58810530
100quinone biosynthetic process (GO:1901663)3.58281884
101short-chain fatty acid metabolic process (GO:0046459)3.58225987
102phenylpropanoid metabolic process (GO:0009698)3.58111419
103flavonoid metabolic process (GO:0009812)3.56797298
104exogenous drug catabolic process (GO:0042738)3.54722976
105sterol homeostasis (GO:0055092)3.54286909
106protein activation cascade (GO:0072376)3.51657390
107carnitine metabolic process (GO:0009437)3.48134349
108monocarboxylic acid catabolic process (GO:0072329)3.47953869
109complement activation, classical pathway (GO:0006958)3.45271888
110behavioral response to nicotine (GO:0035095)3.43443313
111L-methionine salvage (GO:0071267)3.36377192
112L-methionine biosynthetic process (GO:0071265)3.36377192
113amino acid salvage (GO:0043102)3.36377192
114ubiquinone biosynthetic process (GO:0006744)3.36348173
115L-serine metabolic process (GO:0006563)3.29393493
116quinone metabolic process (GO:1901661)3.29322454
117water-soluble vitamin biosynthetic process (GO:0042364)3.29009043
118alkaloid metabolic process (GO:0009820)3.24911736
119intestinal cholesterol absorption (GO:0030299)3.22581779
120pyrimidine nucleobase catabolic process (GO:0006208)3.18113708
121heme transport (GO:0015886)3.13784823
122response to misfolded protein (GO:0051788)3.11251172
123ubiquinone metabolic process (GO:0006743)3.05780113
124positive regulation of triglyceride metabolic process (GO:0090208)3.05655439
125daunorubicin metabolic process (GO:0044597)2.97380400
126polyketide metabolic process (GO:0030638)2.97380400
127doxorubicin metabolic process (GO:0044598)2.97380400
128proline metabolic process (GO:0006560)2.97306441
129nucleobase catabolic process (GO:0046113)2.88493316
130peptidyl-glutamic acid modification (GO:0018200)2.82702507
131ethanol metabolic process (GO:0006067)2.81289849
132sulfur amino acid metabolic process (GO:0000096)2.80899596
133regulation of lipoprotein particle clearance (GO:0010984)2.79469879
134aminoglycoside antibiotic metabolic process (GO:0030647)2.79455858

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse8.01169376
2EGR1_23403033_ChIP-Seq_LIVER_Mouse7.26380087
3* PPARA_22158963_ChIP-Seq_LIVER_Mouse6.77552081
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.16191651
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.19985942
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.15001190
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.26589978
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.11954809
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.89630662
10NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.87187655
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.90950840
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.59869260
13CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.34208606
14ZNF274_21170338_ChIP-Seq_K562_Hela2.31702988
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.09499855
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.03305602
17ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.2727105
18TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.97547851
19HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.96396811
20P68_20966046_ChIP-Seq_HELA_Human1.93355381
21HTT_18923047_ChIP-ChIP_STHdh_Human1.88611625
22ETS1_20019798_ChIP-Seq_JURKAT_Human1.85022998
23E2F1_20622854_ChIP-Seq_HELA_Human1.82860269
24TET1_21451524_ChIP-Seq_MESCs_Mouse1.80456367
25BCL6_27268052_Chip-Seq_Bcells_Human1.79046220
26TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76429081
27PHF8_20622854_ChIP-Seq_HELA_Human1.75469188
28* ERA_21632823_ChIP-Seq_H3396_Human1.68063827
29ELF1_20517297_ChIP-Seq_JURKAT_Human1.64821176
30GABP_19822575_ChIP-Seq_HepG2_Human1.62102584
31GABP_17652178_ChIP-ChIP_JURKAT_Human1.61937947
32YY1_22570637_ChIP-Seq_MALME-3M_Human1.61002391
33CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.60509816
34GATA1_22025678_ChIP-Seq_K562_Human1.58967206
35* CTCF_27219007_Chip-Seq_Bcells_Human1.54476927
36ZNF263_19887448_ChIP-Seq_K562_Human1.52404005
37RAC3_21632823_ChIP-Seq_H3396_Human1.52007691
38EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.50549081
39CTCF_20526341_ChIP-Seq_ESCs_Human1.50288760
40STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.50103588
41SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.46295534
42IRF8_22096565_ChIP-ChIP_GC-B_Human1.46155194
43BCOR_27268052_Chip-Seq_Bcells_Human1.45918763
44FOXP1_21924763_ChIP-Seq_HESCs_Human1.45182811
45IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.44024813
46OCT4_20526341_ChIP-Seq_ESCs_Human1.38400090
47RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.38321692
48SA1_27219007_Chip-Seq_Bcells_Human1.38066909
49FOXA2_19822575_ChIP-Seq_HepG2_Human1.37677438
50* HNF4A_19822575_ChIP-Seq_HepG2_Human1.35711088
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.33196117
52* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.32094985
53TAF2_19829295_ChIP-Seq_ESCs_Human1.31240937
54P53_21459846_ChIP-Seq_SAOS-2_Human1.30696966
55* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30246434
56LXR_22292898_ChIP-Seq_THP-1_Human1.26457593
57YY1_21170310_ChIP-Seq_MESCs_Mouse1.24068082
58P300_27268052_Chip-Seq_Bcells_Human1.22910374
59* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.20100604
60EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.19587692
61* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.18882731
62RXRA_24833708_ChIP-Seq_LIVER_Mouse1.17522985
63KAP1_22055183_ChIP-Seq_ESCs_Mouse1.16614289
64E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.16511619
65DCP1A_22483619_ChIP-Seq_HELA_Human1.14691562
66XRN2_22483619_ChIP-Seq_HELA_Human1.14130328
67MYC_19829295_ChIP-Seq_ESCs_Human1.13499176
68* SMC4_20622854_ChIP-Seq_HELA_Human1.12468380
69DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11730913
70IGF1R_20145208_ChIP-Seq_DFB_Human1.11362390
71NANOG_20526341_ChIP-Seq_ESCs_Human1.11061580
72EST1_17652178_ChIP-ChIP_JURKAT_Human1.10527807
73HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.09936485
74* SOX2_21211035_ChIP-Seq_LN229_Human1.09274355
75THAP11_20581084_ChIP-Seq_MESCs_Mouse1.08961560
76PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.06464888
77NCOR_22424771_ChIP-Seq_293T_Human1.03895957
78ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03226305
79Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.02912608
80* CTCF_26484167_Chip-Seq_Bcells_Mouse1.02866470
81VDR_22108803_ChIP-Seq_LS180_Human1.02703132
82PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01888126
83TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01762330
84TP53_22573176_ChIP-Seq_HFKS_Human1.00809446
85LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99846297
86SA1_27219007_Chip-Seq_ERYTHROID_Human0.99812366
87THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.99447556
88* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.98975609
89NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.98073688
90CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.97637593
91PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.97373271
92BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.97239784
93FOXH1_21741376_ChIP-Seq_ESCs_Human0.96707945
94ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96649429
95KDM5A_27292631_Chip-Seq_BREAST_Human0.96405533
96CTCF_21964334_Chip-Seq_Bcells_Human0.95724585
97EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95380530
98SOX2_22085726_ChIP-Seq_NPCs_Mouse0.95211999
99GATA3_21878914_ChIP-Seq_MCF-7_Human0.94398488
100TAF15_26573619_Chip-Seq_HEK293_Human0.92091410
101CLOCK_20551151_ChIP-Seq_293T_Human0.90835494
102GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.89330654
103AUTS2_25519132_ChIP-Seq_293T-REX_Human0.84646936
104NFE2_27457419_Chip-Seq_LIVER_Mouse0.81978987
105GATA4_25053715_ChIP-Seq_YYC3_Human0.80579291
106NRF2_20460467_ChIP-Seq_MEFs_Mouse0.80081109
107NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.80081109
108SUZ12_27294783_Chip-Seq_NPCs_Mouse0.79710701
109AR_20517297_ChIP-Seq_VCAP_Human0.79705870
110EZH2_27294783_Chip-Seq_NPCs_Mouse0.78770313
111CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.75691749
112STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.75387379
113STAT1_17558387_ChIP-Seq_HELA_Human0.73219934
114SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.73009968
115CRX_20693478_ChIP-Seq_RETINA_Mouse0.70016143
116SOX2_27498859_Chip-Seq_STOMACH_Mouse0.69323317
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.68597263
118RARA_24833708_ChIP-Seq_LIVER_Mouse0.67848349
119IRF1_19129219_ChIP-ChIP_H3396_Human0.67368724
120RUNX1_27457419_Chip-Seq_LIVER_Mouse0.67102437
121BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.66028126
122OCT4_21477851_ChIP-Seq_ESCs_Mouse0.65109171
123AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.63975067
124SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.62504679
125BCAT_22108803_ChIP-Seq_LS180_Human0.62409631
126RAD21_21589869_ChIP-Seq_MESCs_Mouse0.62363717
127TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.61035083
128ESR1_15608294_ChIP-ChIP_MCF-7_Human0.60881367
129GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.60727174
130PIAS1_25552417_ChIP-Seq_VCAP_Human0.58732132
131RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.58590057
132FLI1_27457419_Chip-Seq_LIVER_Mouse0.58402058
133* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.58005202
134PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.57408480
135EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.57389510
136CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.57384157
137PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.56773469
138ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.56691354
139PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.56637332
140SMAD1_18555785_Chip-Seq_ESCs_Mouse0.55420237
141FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.55184332
142CBP_21632823_ChIP-Seq_H3396_Human0.54498286
143* PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.54341997
144GBX2_23144817_ChIP-Seq_PC3_Human0.53946199
145ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.53450283
146PU1_27457419_Chip-Seq_LIVER_Mouse0.52843111
147RARB_24833708_ChIP-Seq_LIVER_Mouse0.52679163
148AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.52533552
149EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.52316762
150ESRRB_18555785_Chip-Seq_ESCs_Mouse0.52231785
151SALL4_18804426_ChIP-ChIP_XEN_Mouse0.52018405
152NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.51997148
153CEBPB_22108803_ChIP-Seq_LS180_Human0.51845591
154EGR1_19032775_ChIP-ChIP_M12_Human0.51731841
155FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.51457947
156* MYC_19915707_ChIP-ChIP_AK7_Human0.51041045
157CDX2_22108803_ChIP-Seq_LS180_Human0.50503631
158LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.50192592
159* ESET_19884257_ChIP-Seq_ESCs_Mouse0.49804277
160OCT4_18555785_Chip-Seq_ESCs_Mouse0.49053980
161SRF_21415370_ChIP-Seq_HL-1_Mouse0.48967785
162FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.48193303
163P53_22387025_ChIP-Seq_ESCs_Mouse0.47082035
164RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.47018267
165STAT3_18555785_Chip-Seq_ESCs_Mouse0.46970340
166IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.46824382
167FOXA1_25552417_ChIP-Seq_VCAP_Human0.46819482
168CDX2_20551321_ChIP-Seq_CACO-2_Human0.45037860
169FOXH1_21741376_ChIP-Seq_EPCs_Human0.44999765
170PCGF2_27294783_Chip-Seq_ESCs_Mouse0.44975732
171ZFP57_27257070_Chip-Seq_ESCs_Mouse0.44553232

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.20870137
2MP0005360_urolithiasis7.23630101
3MP0005085_abnormal_gallbladder_physiolo6.44978536
4MP0005365_abnormal_bile_salt6.29795995
5MP0008875_abnormal_xenobiotic_pharmacok5.24901421
6MP0003252_abnormal_bile_duct3.91785075
7MP0003806_abnormal_nucleotide_metabolis3.91369943
8MP0010329_abnormal_lipoprotein_level3.54013604
9MP0003195_calcinosis2.93354551
10MP0009840_abnormal_foam_cell2.88954180
11MP0005083_abnormal_biliary_tract2.87355961
12MP0005332_abnormal_amino_acid2.84395823
13MP0001666_abnormal_nutrient_absorption2.58934837
14MP0004019_abnormal_vitamin_homeostasis2.36222499
15MP0003191_abnormal_cellular_cholesterol2.20189648
16MP0002138_abnormal_hepatobiliary_system2.16705669
17MP0009697_abnormal_copulation2.13393936
18MP0000609_abnormal_liver_physiology2.07536395
19MP0002118_abnormal_lipid_homeostasis2.05224937
20MP0001986_abnormal_taste_sensitivity2.02301852
21MP0003868_abnormal_feces_composition2.01961700
22MP0001764_abnormal_homeostasis1.92998732
23MP0005319_abnormal_enzyme/_coenzyme1.80499295
24MP0005451_abnormal_body_composition1.71544559
25MP0004147_increased_porphyrin_level1.62564510
26MP0006292_abnormal_olfactory_placode1.61304112
27MP0005584_abnormal_enzyme/coenzyme_acti1.53606660
28MP0003646_muscle_fatigue1.53444401
29MP0002876_abnormal_thyroid_physiology1.51179782
30MP0003011_delayed_dark_adaptation1.50975473
31MP0004133_heterotaxia1.50264843
32MP0003186_abnormal_redox_activity1.49866440
33MP0001968_abnormal_touch/_nociception1.47073151
34MP0000013_abnormal_adipose_tissue1.32873607
35MP0005551_abnormal_eye_electrophysiolog1.31800013
36MP0002653_abnormal_ependyma_morphology1.29519827
37MP0009643_abnormal_urine_homeostasis1.27827416
38MP0009764_decreased_sensitivity_to1.27538899
39MP0003879_abnormal_hair_cell1.24678838
40MP0005647_abnormal_sex_gland1.22444403
41MP0002736_abnormal_nociception_after1.15417223
42MP0000598_abnormal_liver_morphology1.10562443
43MP0006276_abnormal_autonomic_nervous1.09340706
44MP0005670_abnormal_white_adipose1.08719005
45MP0008789_abnormal_olfactory_epithelium1.06336173
46MP0008995_early_reproductive_senescence1.05760387
47MP0003122_maternal_imprinting1.05225327
48MP0005084_abnormal_gallbladder_morpholo1.04876733
49MP0003656_abnormal_erythrocyte_physiolo1.03692732
50MP0000003_abnormal_adipose_tissue1.02318288
51MP0001529_abnormal_vocalization1.00408368
52MP0009763_increased_sensitivity_to0.99848571
53MP0005636_abnormal_mineral_homeostasis0.99478874
54MP0002254_reproductive_system_inflammat0.99380890
55MP0002160_abnormal_reproductive_system0.97365628
56MP0008469_abnormal_protein_level0.95430961
57MP0009384_cardiac_valve_regurgitation0.93945264
58MP0005408_hypopigmentation0.91473847
59MP0009642_abnormal_blood_homeostasis0.90643662
60MP0002938_white_spotting0.90622159
61MP0002234_abnormal_pharynx_morphology0.89547461
62MP0008775_abnormal_heart_ventricle0.89288250
63MP0006036_abnormal_mitochondrial_physio0.85678186
64MP0002249_abnormal_larynx_morphology0.85293352
65MP0009765_abnormal_xenobiotic_induced0.84228290
66MP0004142_abnormal_muscle_tone0.83019857
67MP0002102_abnormal_ear_morphology0.82478265
68MP0002078_abnormal_glucose_homeostasis0.81744254
69MP0001502_abnormal_circadian_rhythm0.81332974
70MP0005376_homeostasis/metabolism_phenot0.80634131
71MP0005220_abnormal_exocrine_pancreas0.79898672
72MP0002638_abnormal_pupillary_reflex0.79728271
73MP0005058_abnormal_lysosome_morphology0.79685140
74MP0001905_abnormal_dopamine_level0.79546819
75MP0002735_abnormal_chemical_nociception0.77241463
76MP0005389_reproductive_system_phenotype0.75808633
77MP0000049_abnormal_middle_ear0.75232575
78MP0005535_abnormal_body_temperature0.74546505
79MP0008877_abnormal_DNA_methylation0.74490044
80MP0000678_abnormal_parathyroid_gland0.74208977
81MP0004145_abnormal_muscle_electrophysio0.73427184
82MP0003724_increased_susceptibility_to0.73225094
83MP0001756_abnormal_urination0.72925423
84MP0005334_abnormal_fat_pad0.72590495
85MP0005394_taste/olfaction_phenotype0.72297639
86MP0005499_abnormal_olfactory_system0.72297639
87MP0005410_abnormal_fertilization0.71705383
88MP0000604_amyloidosis0.71575707
89MP0004782_abnormal_surfactant_physiolog0.71055680
90MP0002557_abnormal_social/conspecific_i0.68749553
91MP0001661_extended_life_span0.68234072
92MP0009745_abnormal_behavioral_response0.66029449
93MP0005266_abnormal_metabolism0.62835908
94MP0003878_abnormal_ear_physiology0.62217886
95MP0005377_hearing/vestibular/ear_phenot0.62217886
96MP0003698_abnormal_male_reproductive0.61803641
97MP0002733_abnormal_thermal_nociception0.61688829
98MP0002971_abnormal_brown_adipose0.61587756
99MP0000372_irregular_coat_pigmentation0.59951250
100MP0010368_abnormal_lymphatic_system0.59637254
101MP0002282_abnormal_trachea_morphology0.59413232
102MP0006035_abnormal_mitochondrial_morpho0.59033233
103MP0003137_abnormal_impulse_conducting0.58389583
104MP0003938_abnormal_ear_development0.58347141
105MP0005645_abnormal_hypothalamus_physiol0.57547641
106MP0005448_abnormal_energy_balance0.57515787
107MP0003718_maternal_effect0.57295139
108MP0000639_abnormal_adrenal_gland0.56804355
109MP0000026_abnormal_inner_ear0.56627532
110MP0005464_abnormal_platelet_physiology0.55250896
111MP0002132_abnormal_respiratory_system0.54839205
112MP0004381_abnormal_hair_follicle0.54069087
113MP0005395_other_phenotype0.50993821
114MP0002928_abnormal_bile_duct0.50829487
115MP0002136_abnormal_kidney_physiology0.50296660
116MP0004130_abnormal_muscle_cell0.49664665
117MP0003953_abnormal_hormone_level0.48693460
118MP0003638_abnormal_response/metabolism_0.47418827
119MP0003436_decreased_susceptibility_to0.47096780
120MP0008872_abnormal_physiological_respon0.46414470
121MP0005248_abnormal_Harderian_gland0.45418236
122MP0002822_catalepsy0.44844751
123MP0000230_abnormal_systemic_arterial0.42562345
124MP0001853_heart_inflammation0.41834633
125MP0009053_abnormal_anal_canal0.41428987
126MP0003690_abnormal_glial_cell0.41189562
127MP0005646_abnormal_pituitary_gland0.40132419
128MP0005075_abnormal_melanosome_morpholog0.38884757
129MP0008874_decreased_physiological_sensi0.37288071
130MP0004264_abnormal_extraembryonic_tissu0.37046003
131MP0009785_altered_susceptibility_to0.36954005
132MP0001845_abnormal_inflammatory_respons0.36820839
133MP0000566_synostosis0.36480513
134MP0003705_abnormal_hypodermis_morpholog0.35535806
135MP0008873_increased_physiological_sensi0.34433511
136MP0002837_dystrophic_cardiac_calcinosis0.34096999
137MP0000579_abnormal_nail_morphology0.33812007
138MP0009115_abnormal_fat_cell0.32822576
139MP0000538_abnormal_urinary_bladder0.31281017
140MP0005166_decreased_susceptibility_to0.30985135
141MP0002168_other_aberrant_phenotype0.30838044
142MP0006082_CNS_inflammation0.30778115
143MP0001881_abnormal_mammary_gland0.30626675
144MP0000427_abnormal_hair_cycle0.28342621
145MP0005379_endocrine/exocrine_gland_phen0.28119401
146MP0001324_abnormal_eye_pigmentation0.27599433
147MP0004883_abnormal_blood_vessel0.26758070
148MP0003075_altered_response_to0.26734439
149MP0005666_abnormal_adipose_tissue0.26002218
150MP0004043_abnormal_pH_regulation0.25881338

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.19741073
2Intrahepatic cholestasis (HP:0001406)7.01261929
3Prolonged partial thromboplastin time (HP:0003645)6.61326454
4Deep venous thrombosis (HP:0002625)6.51465952
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.50265526
6Hypobetalipoproteinemia (HP:0003563)6.11058320
7Xanthomatosis (HP:0000991)5.81935663
8Hyperlipoproteinemia (HP:0010980)5.28902900
9Joint hemorrhage (HP:0005261)4.89379397
10Complement deficiency (HP:0004431)4.69583016
11Hypolipoproteinemia (HP:0010981)4.57939740
12Hyperammonemia (HP:0001987)4.48303432
13Abnormality of methionine metabolism (HP:0010901)4.39762281
14Hyperglycinemia (HP:0002154)4.38015731
15Epidermoid cyst (HP:0200040)4.31330645
16Abnormality of aspartate family amino acid metabolism (HP:0010899)4.22768725
17Abnormality of glutamine family amino acid metabolism (HP:0010902)4.20741487
18Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.19990010
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.16385701
20Ketosis (HP:0001946)4.14164350
21Hyperglycinuria (HP:0003108)4.13949832
22Abnormality of pyrimidine metabolism (HP:0004353)4.13262140
23Conjugated hyperbilirubinemia (HP:0002908)4.13005858
24Abnormality of the common coagulation pathway (HP:0010990)4.11781721
25Fat malabsorption (HP:0002630)4.09842363
26Hypoalphalipoproteinemia (HP:0003233)4.02674736
27Hypoglycemic coma (HP:0001325)3.92771381
28Abnormality of glycine metabolism (HP:0010895)3.88203851
29Abnormality of serine family amino acid metabolism (HP:0010894)3.88203851
30Abnormality of the intrinsic pathway (HP:0010989)3.75901670
31Abnormality of fatty-acid metabolism (HP:0004359)3.57591715
32Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.51030156
33Hypercholesterolemia (HP:0003124)3.43536632
34Abnormality of complement system (HP:0005339)3.42141858
35Hyperbilirubinemia (HP:0002904)3.37100975
36Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.34835436
37Abnormality of alanine metabolism (HP:0010916)3.34835436
38Hyperalaninemia (HP:0003348)3.34835436
39Abnormality of serum amino acid levels (HP:0003112)3.22461577
40Abnormality of nucleobase metabolism (HP:0010932)3.22109909
41Steatorrhea (HP:0002570)3.12599023
42Cerebral palsy (HP:0100021)3.06510299
43Acute encephalopathy (HP:0006846)3.05672357
44Delayed CNS myelination (HP:0002188)3.04284658
45Ketoacidosis (HP:0001993)2.98868413
46Hepatic necrosis (HP:0002605)2.96375939
47Metabolic acidosis (HP:0001942)2.93250238
48Hepatocellular necrosis (HP:0001404)2.89024788
49Spontaneous abortion (HP:0005268)2.83637338
50Lethargy (HP:0001254)2.81964445
51Dicarboxylic aciduria (HP:0003215)2.76937088
52Abnormality of dicarboxylic acid metabolism (HP:0010995)2.76937088
53Hepatocellular carcinoma (HP:0001402)2.76915787
54Abnormality of purine metabolism (HP:0004352)2.76533793
55Hypoglycemic seizures (HP:0002173)2.72151268
56Mitochondrial inheritance (HP:0001427)2.71191548
57Systemic lupus erythematosus (HP:0002725)2.66500219
58Hypochromic microcytic anemia (HP:0004840)2.66148015
59Myocardial infarction (HP:0001658)2.65293333
60Cerebral edema (HP:0002181)2.64554019
61Abnormal mitochondria in muscle tissue (HP:0008316)2.61278592
62Acute necrotizing encephalopathy (HP:0006965)2.60618955
63Renal cortical cysts (HP:0000803)2.58063024
64Generalized aminoaciduria (HP:0002909)2.56463399
65Skin nodule (HP:0200036)2.56282406
66Increased CSF lactate (HP:0002490)2.56099091
67Vascular calcification (HP:0004934)2.55767135
68Mesangial abnormality (HP:0001966)2.50075990
69Gout (HP:0001997)2.45159183
70Increased serum lactate (HP:0002151)2.43573000
71Retinal atrophy (HP:0001105)2.41659897
72Methylmalonic aciduria (HP:0012120)2.40735443
73Lactic acidosis (HP:0003128)2.40349790
74Acanthocytosis (HP:0001927)2.40132573
75Glomerulonephritis (HP:0000099)2.32711106
76Enlarged kidneys (HP:0000105)2.31834149
77Irritability (HP:0000737)2.27169133
78Type II lissencephaly (HP:0007260)2.26733853
79Pancreatitis (HP:0001733)2.25794666
80Increased muscle lipid content (HP:0009058)2.24962878
81Brushfield spots (HP:0001088)2.24439184
82Mitral stenosis (HP:0001718)2.23933100
83Recurrent gram-negative bacterial infections (HP:0005420)2.23362842
84Reduced antithrombin III activity (HP:0001976)2.22921738
85Cardiovascular calcification (HP:0011915)2.22135767
86Abnormal gallbladder morphology (HP:0012437)2.21557494
87Menorrhagia (HP:0000132)2.21541149
88Gingival bleeding (HP:0000225)2.21105481
89Increased serum pyruvate (HP:0003542)2.20979510
90Opisthotonus (HP:0002179)2.19831894
91Decreased electroretinogram (ERG) amplitude (HP:0000654)2.19225752
92Hyperinsulinemic hypoglycemia (HP:0000825)2.16536262
93Lipid accumulation in hepatocytes (HP:0006561)2.16517964
94Proximal tubulopathy (HP:0000114)2.16478212
95Severe muscular hypotonia (HP:0006829)2.16299956
96Hyperphosphaturia (HP:0003109)2.15427132
97Vomiting (HP:0002013)2.15073845
98Sensorimotor neuropathy (HP:0007141)2.13417440
99Molar tooth sign on MRI (HP:0002419)2.12550292
100Abnormality of midbrain morphology (HP:0002418)2.12550292
101Rib fusion (HP:0000902)2.10933982
102Cholelithiasis (HP:0001081)2.09357595
103Alkalosis (HP:0001948)2.05954564
104Neonatal onset (HP:0003623)2.05916976
105Amyloidosis (HP:0011034)2.05803890
106Spastic diplegia (HP:0001264)2.05614627
107Malnutrition (HP:0004395)2.05172510
108Retinal dysplasia (HP:0007973)2.04995496
109Renal Fanconi syndrome (HP:0001994)2.02834976
110Increased intramyocellular lipid droplets (HP:0012240)2.00768581
111Hydroxyprolinuria (HP:0003080)2.00543196
112Abnormality of proline metabolism (HP:0010907)2.00543196
113Glycosuria (HP:0003076)2.00163790
114Abnormality of urine glucose concentration (HP:0011016)2.00163790
115Elevated hepatic transaminases (HP:0002910)1.98784421
116Esophageal varix (HP:0002040)1.97906393
117Type I transferrin isoform profile (HP:0003642)1.97760107
118Symptomatic seizures (HP:0011145)1.96030497
119Fair hair (HP:0002286)1.94903418
120Abnormal urine phosphate concentration (HP:0012599)1.94735429
121Pendular nystagmus (HP:0012043)1.94659211
122Abnormal gallbladder physiology (HP:0012438)1.93436607
123Cholecystitis (HP:0001082)1.93436607
124Abnormal protein glycosylation (HP:0012346)1.92773498
125Abnormal glycosylation (HP:0012345)1.92773498
126Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.92773498
127Abnormal protein N-linked glycosylation (HP:0012347)1.92773498
128Thrombophlebitis (HP:0004418)1.92364906
129Rickets (HP:0002748)1.92184094
130Late onset (HP:0003584)1.90880183
131Congenital stationary night blindness (HP:0007642)1.90223621
132Abnormality of glycolysis (HP:0004366)1.89252604
133Hyperglycemia (HP:0003074)1.88059097
134Poikilocytosis (HP:0004447)1.87936053
135Progressive microcephaly (HP:0000253)1.84590818
136Progressive macrocephaly (HP:0004481)1.83363634
137Abnormality of vitamin metabolism (HP:0100508)1.83058643
138Acute hepatic failure (HP:0006554)1.82858331
139Abnormality of the gallbladder (HP:0005264)1.82678077
140Nephronophthisis (HP:0000090)1.82395542
141Hemorrhage of the eye (HP:0011885)1.80723273
142CNS demyelination (HP:0007305)1.80261715
143Hypophosphatemic rickets (HP:0004912)1.80076015
144Methylmalonic acidemia (HP:0002912)1.79729242
145Increased hepatocellular lipid droplets (HP:0006565)1.77812334
146Testicular atrophy (HP:0000029)1.77776112
147Pancreatic cysts (HP:0001737)1.77105432
148Tachypnea (HP:0002789)1.76664900
149Patellar aplasia (HP:0006443)1.75491236
150Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.74284395
151Decreased activity of mitochondrial respiratory chain (HP:0008972)1.74284395

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.39571677
2INSRR3.74307603
3FGFR43.45436524
4SIK13.45038456
5WNK43.32183321
6MAP4K23.15622536
7TAOK32.77648803
8TLK12.76933197
9ERN12.71912761
10IRAK32.59388773
11FRK2.47275447
12ERBB42.35813610
13MAPKAPK32.33440900
14FLT32.25838586
15MAP3K142.13400594
16MAP2K42.11962740
17STK38L2.02617189
18AKT31.99752534
19PHKG21.99744338
20PHKG11.99744338
21VRK21.93934183
22PIK3CG1.89177878
23PINK11.85109626
24CASK1.84405729
25NME11.80843828
26PDK21.77301611
27DYRK21.74927879
28MUSK1.71005316
29NEK91.68590875
30TYK21.66450799
31WNK31.62083336
32MST1R1.55960716
33MAPK111.52225805
34MAP2K21.49241316
35PIM21.47746327
36MAPK131.40233025
37SGK21.36001774
38STK161.35691775
39CSNK1G31.31181326
40TESK21.30882688
41MAP3K111.29034817
42PRKCI1.23996654
43MAP2K71.23332295
44ABL21.20587675
45DAPK21.19608046
46LIMK11.19069661
47MAP3K41.17244783
48JAK11.16042781
49TBK11.15120595
50OXSR11.15040694
51EPHA31.14516335
52STK391.13071729
53IKBKE1.08703256
54IRAK11.08244956
55ZAK1.08032311
56PRKAA21.06087955
57IRAK41.03237424
58MAP2K61.02759176
59PRKD31.02100403
60TIE11.01991875
61CCNB11.01871896
62ADRBK21.01530714
63TESK11.00647731
64SIK20.98742566
65MARK10.98432299
66EPHB20.98342792
67SIK30.97871354
68BMPR1B0.96964952
69CSNK1G10.96357801
70CSNK1A1L0.95915177
71SGK30.95103800
72NME20.95084065
73KDR0.94414560
74LATS10.94392838
75JAK20.94026751
76GRK10.86401651
77MET0.83611987
78TAOK20.83369368
79NLK0.80965620
80EIF2AK20.80743605
81PRKCZ0.79959513
82MAPK70.79638147
83MAPK40.79238369
84IRAK20.78017486
85NUAK10.76668425
86BMPR20.76277803
87ADRBK10.75812112
88CSNK1G20.75486089
89TXK0.74915306
90AURKA0.72712464
91CSNK1A10.72523250
92MAPK150.70600901
93MYLK0.69652144
94OBSCN0.69117592
95MAP3K70.68413005
96PRKD20.67659673
97SGK4940.66941000
98SGK2230.66941000
99PAK30.66046390
100CAMK2G0.65171653
101TRIB30.64820477
102MAP2K30.64616421
103RPS6KB20.64304292
104KIT0.64157382
105RPS6KA50.63962524
106PRKACG0.62755730
107IKBKB0.60680711
108PKN20.60661104
109TEC0.59878848
110PTK60.59518173
111PRKACA0.58894966
112FGFR30.57927713
113MAPK120.57706072
114PRKAA10.57575721
115PRKCG0.57473556
116TGFBR20.57038947
117PRKCE0.55707365
118MAP3K50.53462670
119MAPKAPK50.52957908
120RPS6KA20.52673687
121ERBB20.52670796
122CDK190.51583217
123RPS6KA60.51355213
124DYRK1B0.50886381
125MAP3K30.50660696
126VRK10.50109354
127PIK3CA0.48418777
128CHUK0.48216637
129EPHA20.48002227
130CAMK2D0.47498805
131PBK0.47045221
132FGFR20.46119999
133MAP3K60.45502989
134CDK80.45313675
135MAP2K10.44690912
136TNIK0.44582653
137ATR0.44534948
138CSNK2A10.43607384
139IGF1R0.43584511
140PRKCQ0.43569721
141ACVR1B0.41851897
142AKT20.41748719
143GRK70.40457814
144PAK60.39769878
145EPHA40.38309774
146CSK0.37051553
147JAK30.36484929
148PLK10.35763690
149CAMK10.35295747
150TNK20.35002434
151GRK60.34977556
152NEK20.34911953
153LYN0.34784159
154CSF1R0.34143694
155EIF2AK30.32987801
156RPS6KB10.32818678
157GSK3A0.32608619
158PRKCA0.31589523
159BLK0.31563667
160STK240.31527140
161CAMK40.30988037
162DAPK10.28433317

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.39235786
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.33466024
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.21806365
4Nitrogen metabolism_Homo sapiens_hsa009103.00769736
5Arginine biosynthesis_Homo sapiens_hsa002202.89750219
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.76235034
7Tryptophan metabolism_Homo sapiens_hsa003802.74857630
8Complement and coagulation cascades_Homo sapiens_hsa046102.57256993
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.52212522
10Fatty acid degradation_Homo sapiens_hsa000712.51989952
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.45478076
12Pentose and glucuronate interconversions_Homo sapiens_hsa000402.41628248
13Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.38437836
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.19613487
15* Peroxisome_Homo sapiens_hsa041462.16976370
16Butanoate metabolism_Homo sapiens_hsa006502.12850653
17Steroid hormone biosynthesis_Homo sapiens_hsa001402.06340860
18Chemical carcinogenesis_Homo sapiens_hsa052041.99674576
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.99655161
20Propanoate metabolism_Homo sapiens_hsa006401.99601111
21Histidine metabolism_Homo sapiens_hsa003401.95763130
22Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.90142067
23beta-Alanine metabolism_Homo sapiens_hsa004101.88038793
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.86743732
25Fatty acid metabolism_Homo sapiens_hsa012121.84579271
26Retinol metabolism_Homo sapiens_hsa008301.84154799
27PPAR signaling pathway_Homo sapiens_hsa033201.83242980
28Caffeine metabolism_Homo sapiens_hsa002321.75292184
29Staphylococcus aureus infection_Homo sapiens_hsa051501.65777786
30Selenocompound metabolism_Homo sapiens_hsa004501.65183033
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.63530547
32Phenylalanine metabolism_Homo sapiens_hsa003601.61364925
33Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.61121346
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58704786
35Fatty acid elongation_Homo sapiens_hsa000621.51257040
36Sulfur metabolism_Homo sapiens_hsa009201.45411873
37Tyrosine metabolism_Homo sapiens_hsa003501.44488599
382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.44018234
39Bile secretion_Homo sapiens_hsa049761.38602419
40Pyruvate metabolism_Homo sapiens_hsa006201.37209353
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.36127555
42Starch and sucrose metabolism_Homo sapiens_hsa005001.34651303
43Oxidative phosphorylation_Homo sapiens_hsa001901.32030966
44Folate biosynthesis_Homo sapiens_hsa007901.32025519
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.26514313
46ABC transporters_Homo sapiens_hsa020101.25416168
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.22664284
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.17709256
49Steroid biosynthesis_Homo sapiens_hsa001001.13594189
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.10900837
51Fat digestion and absorption_Homo sapiens_hsa049751.09296027
52Vitamin digestion and absorption_Homo sapiens_hsa049771.08065704
53Biosynthesis of amino acids_Homo sapiens_hsa012301.06782006
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.06139102
55Carbon metabolism_Homo sapiens_hsa012001.05663729
56Parkinsons disease_Homo sapiens_hsa050121.02047640
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.01496662
58Arginine and proline metabolism_Homo sapiens_hsa003300.98972813
59Vitamin B6 metabolism_Homo sapiens_hsa007500.90567213
60Cyanoamino acid metabolism_Homo sapiens_hsa004600.86295530
61Sulfur relay system_Homo sapiens_hsa041220.84157458
62Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77144864
63One carbon pool by folate_Homo sapiens_hsa006700.76273255
64Lysine degradation_Homo sapiens_hsa003100.73770913
65RNA polymerase_Homo sapiens_hsa030200.69955226
66Glycerolipid metabolism_Homo sapiens_hsa005610.67686733
67Base excision repair_Homo sapiens_hsa034100.67607804
68Glutathione metabolism_Homo sapiens_hsa004800.64498473
69Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63171444
70Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62572672
71Phototransduction_Homo sapiens_hsa047440.60553113
72Ether lipid metabolism_Homo sapiens_hsa005650.57874398
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56617128
74Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55173907
75Metabolic pathways_Homo sapiens_hsa011000.54253398
76Huntingtons disease_Homo sapiens_hsa050160.53208966
77Pentose phosphate pathway_Homo sapiens_hsa000300.52288019
78Homologous recombination_Homo sapiens_hsa034400.45271316
79Alzheimers disease_Homo sapiens_hsa050100.44820368
80Fatty acid biosynthesis_Homo sapiens_hsa000610.43936596
81Cardiac muscle contraction_Homo sapiens_hsa042600.43638917
82Fanconi anemia pathway_Homo sapiens_hsa034600.42775921
83Other glycan degradation_Homo sapiens_hsa005110.42695355
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.38321782
85Galactose metabolism_Homo sapiens_hsa000520.35533119
86Fructose and mannose metabolism_Homo sapiens_hsa000510.34667286
87Proteasome_Homo sapiens_hsa030500.28511150
88Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.28297464
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26584590
90Collecting duct acid secretion_Homo sapiens_hsa049660.26426326
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.25201728
92Purine metabolism_Homo sapiens_hsa002300.24926708
93Linoleic acid metabolism_Homo sapiens_hsa005910.23460841
94Prion diseases_Homo sapiens_hsa050200.20910280
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.17013158
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.13800384
97Insulin resistance_Homo sapiens_hsa049310.11980360
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.11263289
99Regulation of autophagy_Homo sapiens_hsa041400.07975994
100Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.04343671
101Glucagon signaling pathway_Homo sapiens_hsa049220.03365776
102Arachidonic acid metabolism_Homo sapiens_hsa005900.00314722
103Pertussis_Homo sapiens_hsa05133-0.2203895
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.2167200
105Circadian rhythm_Homo sapiens_hsa04710-0.2103428
106Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601-0.2098462
107Mineral absorption_Homo sapiens_hsa04978-0.2077807
108Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623-0.2065251
109Insulin signaling pathway_Homo sapiens_hsa04910-0.2041110
110Protein export_Homo sapiens_hsa03060-0.1905061
111Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.1699176
112Pyrimidine metabolism_Homo sapiens_hsa00240-0.1676579
113Hepatitis C_Homo sapiens_hsa05160-0.1562878
114AMPK signaling pathway_Homo sapiens_hsa04152-0.1101322
115Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.0948570
116Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0772088
117RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622-0.0767583
118Renin-angiotensin system_Homo sapiens_hsa04614-0.0765997
119Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0723992
120African trypanosomiasis_Homo sapiens_hsa05143-0.0498026
121Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932-0.0032298

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »