Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.72585415 |
2 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.72585415 |
3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.39092628 |
4 | ribosomal small subunit assembly (GO:0000028) | 5.13718942 |
5 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.94302824 |
6 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.50381177 |
7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.44539318 |
8 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.43966523 |
9 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.43966523 |
10 | modulation by symbiont of host immune response (GO:0052553) | 4.43966523 |
11 | positive regulation by symbiont of host defense response (GO:0052509) | 4.43966523 |
12 | modulation by symbiont of host defense response (GO:0052031) | 4.43966523 |
13 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.43966523 |
14 | neutrophil activation involved in immune response (GO:0002283) | 4.40711884 |
15 | viral transcription (GO:0019083) | 4.38404457 |
16 | detection of bacterium (GO:0016045) | 4.27864514 |
17 | detection of other organism (GO:0098543) | 4.27154317 |
18 | translational termination (GO:0006415) | 4.18646435 |
19 | regulation of gamma-delta T cell activation (GO:0046643) | 4.12852425 |
20 | antigen processing and presentation via MHC class Ib (GO:0002475) | 4.08215077 |
21 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.01228536 |
22 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.01001142 |
23 | cellular extravasation (GO:0045123) | 3.85953925 |
24 | tolerance induction (GO:0002507) | 3.85617774 |
25 | ribosomal small subunit biogenesis (GO:0042274) | 3.82659381 |
26 | negative regulation of T cell mediated immunity (GO:0002710) | 3.79428102 |
27 | response to peptidoglycan (GO:0032494) | 3.75889624 |
28 | macrophage activation involved in immune response (GO:0002281) | 3.74456990 |
29 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.69760676 |
30 | translational elongation (GO:0006414) | 3.69388895 |
31 | DNA deamination (GO:0045006) | 3.68533703 |
32 | negative regulation of interleukin-12 production (GO:0032695) | 3.67136124 |
33 | neutrophil activation (GO:0042119) | 3.63998008 |
34 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.62738189 |
35 | leukocyte aggregation (GO:0070486) | 3.61924485 |
36 | negative regulation of phagocytosis (GO:0050765) | 3.60773190 |
37 | response to muramyl dipeptide (GO:0032495) | 3.60066983 |
38 | positive regulation of B cell differentiation (GO:0045579) | 3.59239412 |
39 | positive thymic T cell selection (GO:0045059) | 3.58934764 |
40 | negative T cell selection (GO:0043383) | 3.55758995 |
41 | regulation of T cell tolerance induction (GO:0002664) | 3.53348677 |
42 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.53194413 |
43 | respiratory burst (GO:0045730) | 3.52841805 |
44 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.46063399 |
45 | negative thymic T cell selection (GO:0045060) | 3.45506873 |
46 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.45413954 |
47 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.43146462 |
48 | protein targeting to ER (GO:0045047) | 3.43103198 |
49 | cotranslational protein targeting to membrane (GO:0006613) | 3.43031939 |
50 | detection of external biotic stimulus (GO:0098581) | 3.38555331 |
51 | regulation of B cell differentiation (GO:0045577) | 3.37967561 |
52 | granulocyte activation (GO:0036230) | 3.35804142 |
53 | interferon-gamma production (GO:0032609) | 3.35299973 |
54 | activated T cell proliferation (GO:0050798) | 3.34094488 |
55 | viral life cycle (GO:0019058) | 3.32201166 |
56 | myeloid cell activation involved in immune response (GO:0002275) | 3.31757385 |
57 | regulation of tolerance induction (GO:0002643) | 3.31216125 |
58 | regulation of mast cell degranulation (GO:0043304) | 3.30538297 |
59 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.28009385 |
60 | maturation of SSU-rRNA (GO:0030490) | 3.27033000 |
61 | T cell homeostasis (GO:0043029) | 3.26105117 |
62 | response to interleukin-15 (GO:0070672) | 3.26093392 |
63 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.25969458 |
64 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.25959867 |
65 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.21481903 |
66 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.21481903 |
67 | protein localization to endoplasmic reticulum (GO:0070972) | 3.21414043 |
68 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.21343979 |
69 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.19883581 |
70 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.18575267 |
71 | cellular protein complex disassembly (GO:0043624) | 3.17250330 |
72 | translational initiation (GO:0006413) | 3.15006041 |
73 | T cell migration (GO:0072678) | 3.14994852 |
74 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.14031126 |
75 | mast cell activation (GO:0045576) | 3.13511483 |
76 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.13348876 |
77 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.12681768 |
78 | regulation of regulatory T cell differentiation (GO:0045589) | 3.12218330 |
79 | leukocyte degranulation (GO:0043299) | 3.12179465 |
80 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.12072034 |
81 | thymic T cell selection (GO:0045061) | 3.09800587 |
82 | definitive hemopoiesis (GO:0060216) | 3.07344625 |
83 | negative regulation of innate immune response (GO:0045824) | 3.05135382 |
84 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.04695164 |
85 | DNA unwinding involved in DNA replication (GO:0006268) | 3.04656558 |
86 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.04550743 |
87 | response to host immune response (GO:0052572) | 3.04550743 |
88 | defense response to protozoan (GO:0042832) | 3.04235893 |
89 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.02918583 |
90 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.00804655 |
91 | microglial cell activation (GO:0001774) | 3.00745417 |
92 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.99959522 |
93 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.99900362 |
94 | immunoglobulin mediated immune response (GO:0016064) | 2.98972859 |
95 | regulation of leukocyte degranulation (GO:0043300) | 2.98700887 |
96 | positive T cell selection (GO:0043368) | 2.98133306 |
97 | detection of biotic stimulus (GO:0009595) | 2.96029651 |
98 | megakaryocyte development (GO:0035855) | 2.95679523 |
99 | positive regulation of tolerance induction (GO:0002645) | 2.95522425 |
100 | regulation of antigen processing and presentation (GO:0002577) | 2.95381611 |
101 | B cell receptor signaling pathway (GO:0050853) | 2.94426237 |
102 | NIK/NF-kappaB signaling (GO:0038061) | 2.93719229 |
103 | germinal center formation (GO:0002467) | 2.93323192 |
104 | T cell selection (GO:0045058) | 2.92402028 |
105 | dendritic cell chemotaxis (GO:0002407) | 2.91792915 |
106 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.91192278 |
107 | protein complex disassembly (GO:0043241) | 2.90284255 |
108 | DNA strand elongation (GO:0022616) | 2.89754671 |
109 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.88572835 |
110 | positive regulation of antigen processing and presentation (GO:0002579) | 2.88499454 |
111 | T cell receptor signaling pathway (GO:0050852) | 2.83525029 |
112 | response to protozoan (GO:0001562) | 2.83194200 |
113 | B cell mediated immunity (GO:0019724) | 2.82962679 |
114 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.82720596 |
115 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.82720596 |
116 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.80375964 |
117 | mast cell degranulation (GO:0043303) | 2.80245910 |
118 | mast cell activation involved in immune response (GO:0002279) | 2.80245910 |
119 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.74808184 |
120 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.73053897 |
121 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.72953716 |
122 | regulation of necroptotic process (GO:0060544) | 2.72854894 |
123 | lymphocyte homeostasis (GO:0002260) | 2.70119621 |
124 | cellular response to interleukin-15 (GO:0071350) | 2.70002983 |
125 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.69540096 |
126 | natural killer cell differentiation (GO:0001779) | 2.69125622 |
127 | macromolecular complex disassembly (GO:0032984) | 2.67936955 |
128 | formation of translation preinitiation complex (GO:0001731) | 2.67476283 |
129 | Peyers patch development (GO:0048541) | 2.64260018 |
130 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.64260018 |
131 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.62738308 |
132 | DNA replication initiation (GO:0006270) | 2.62718007 |
133 | positive regulation of granulocyte differentiation (GO:0030854) | 2.62361015 |
134 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.62273374 |
135 | mRNA catabolic process (GO:0006402) | 2.61838731 |
136 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.61553520 |
137 | negative regulation of cell killing (GO:0031342) | 2.61553520 |
138 | telomere maintenance via recombination (GO:0000722) | 2.60690399 |
139 | cellular response to interleukin-4 (GO:0071353) | 2.60547023 |
140 | T cell costimulation (GO:0031295) | 2.59574609 |
141 | lymphocyte costimulation (GO:0031294) | 2.58107524 |
142 | positive regulation of isotype switching (GO:0045830) | 2.56446822 |
143 | response to type I interferon (GO:0034340) | 2.56364302 |
144 | regulation of response to interferon-gamma (GO:0060330) | 2.55108900 |
145 | RNA catabolic process (GO:0006401) | 2.54094642 |
146 | type I interferon signaling pathway (GO:0060337) | 2.53364668 |
147 | cellular response to type I interferon (GO:0071357) | 2.53364668 |
148 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.53273235 |
149 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.52635033 |
150 | leukocyte homeostasis (GO:0001776) | 2.51118041 |
151 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.48572694 |
152 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.48285965 |
153 | natural killer cell activation (GO:0030101) | 2.48173975 |
154 | protein localization to kinetochore (GO:0034501) | 2.48097101 |
155 | lymph node development (GO:0048535) | 2.47734831 |
156 | response to interferon-beta (GO:0035456) | 2.47625024 |
157 | regulation of erythrocyte differentiation (GO:0045646) | 2.46928139 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.08057753 |
2 | MYC_22102868_ChIP-Seq_BL_Human | 3.20218481 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.13042751 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.88084602 |
5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.78505084 |
6 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.74747549 |
7 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.68285461 |
8 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.68024142 |
9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.63787580 |
10 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.62868676 |
11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.62776423 |
12 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.60222425 |
13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.51351019 |
14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.48780489 |
15 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.37380504 |
16 | * RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.27952639 |
17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.24688133 |
18 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.18473652 |
19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.15203721 |
20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.12262764 |
21 | MYB_26560356_Chip-Seq_TH2_Human | 2.11779042 |
22 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.08973973 |
23 | MAF_26560356_Chip-Seq_TH1_Human | 2.08956637 |
24 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.06050446 |
25 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.03212479 |
26 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.01672279 |
27 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.98864566 |
28 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.98698005 |
29 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.94633527 |
30 | UTX_26944678_Chip-Seq_JUKART_Human | 1.92316632 |
31 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.91312395 |
32 | MYB_26560356_Chip-Seq_TH1_Human | 1.89631214 |
33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.87359977 |
34 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.81548188 |
35 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80664315 |
36 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.77873056 |
37 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.76205075 |
38 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.75371098 |
39 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.74279464 |
40 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.74269287 |
41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.73582393 |
42 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.71341154 |
43 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.70738223 |
44 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.66771405 |
45 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.66609944 |
46 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.62666622 |
47 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.61308016 |
48 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.61005485 |
49 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.60273012 |
50 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.59741926 |
51 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.59722350 |
52 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.56075399 |
53 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.56022994 |
54 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.54807328 |
55 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.52388826 |
56 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.51673830 |
57 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.50086343 |
58 | MAF_26560356_Chip-Seq_TH2_Human | 1.48278319 |
59 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.48126788 |
60 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.47193050 |
61 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.45740214 |
62 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.45638752 |
63 | * MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45450239 |
64 | GATA3_26560356_Chip-Seq_TH2_Human | 1.44565352 |
65 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.42477566 |
66 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.41125626 |
67 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.40554808 |
68 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.39870907 |
69 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.37881387 |
70 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.36675243 |
71 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.35503797 |
72 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.32222688 |
73 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.32117853 |
74 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.31268865 |
75 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.31095448 |
76 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.30456113 |
77 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.29615724 |
78 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.28979256 |
79 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.28586631 |
80 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27210951 |
81 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.26240819 |
82 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.25879264 |
83 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.24288062 |
84 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.23756602 |
85 | GATA1_22025678_ChIP-Seq_K562_Human | 1.22951302 |
86 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.22764292 |
87 | GATA1_19941826_ChIP-Seq_K562_Human | 1.22140858 |
88 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.21762360 |
89 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.21263258 |
90 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.19895352 |
91 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.19871449 |
92 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19516104 |
93 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.19230907 |
94 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.17812240 |
95 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.16404209 |
96 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.15577361 |
97 | SPI1_23127762_ChIP-Seq_K562_Human | 1.14569821 |
98 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.14555555 |
99 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14488768 |
100 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.14284894 |
101 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.12368111 |
102 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.12252662 |
103 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.10928269 |
104 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.10614785 |
105 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.10289615 |
106 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.10106137 |
107 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.08494187 |
108 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.07732736 |
109 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.07431874 |
110 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07187900 |
111 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.05024772 |
112 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.05005932 |
113 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.04623930 |
114 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.04136476 |
115 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.02253501 |
116 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.00606564 |
117 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.00553599 |
118 | * RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99800395 |
119 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.99681318 |
120 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.98414093 |
121 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.98019033 |
122 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97630725 |
123 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97006551 |
124 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.96952583 |
125 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.96496708 |
126 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.94812956 |
127 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.94558257 |
128 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.92974879 |
129 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.92033105 |
130 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.91427966 |
131 | P68_20966046_ChIP-Seq_HELA_Human | 0.91004342 |
132 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.90564091 |
133 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90327282 |
134 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89709681 |
135 | P300_27268052_Chip-Seq_Bcells_Human | 0.89510267 |
136 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.84862914 |
137 | GATA2_19941826_ChIP-Seq_K562_Human | 0.83905914 |
138 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.82505779 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002396_abnormal_hematopoietic_system | 3.67797044 |
2 | MP0003763_abnormal_thymus_physiology | 3.66982746 |
3 | MP0001835_abnormal_antigen_presentation | 3.50924469 |
4 | MP0000685_abnormal_immune_system | 3.33486828 |
5 | MP0005671_abnormal_response_to | 3.13120351 |
6 | * MP0001800_abnormal_humoral_immune | 2.71917275 |
7 | * MP0002398_abnormal_bone_marrow | 2.65217961 |
8 | MP0009785_altered_susceptibility_to | 2.57150704 |
9 | MP0003436_decreased_susceptibility_to | 2.50724639 |
10 | * MP0002420_abnormal_adaptive_immunity | 2.45697857 |
11 | MP0004808_abnormal_hematopoietic_stem | 2.45693979 |
12 | MP0002166_altered_tumor_susceptibility | 2.43562881 |
13 | * MP0001819_abnormal_immune_cell | 2.42339602 |
14 | MP0001790_abnormal_immune_system | 2.39694561 |
15 | MP0005387_immune_system_phenotype | 2.39694561 |
16 | * MP0002452_abnormal_antigen_presenting | 2.38446189 |
17 | * MP0002723_abnormal_immune_serum | 2.35006706 |
18 | MP0009333_abnormal_splenocyte_physiolog | 2.34004349 |
19 | MP0005025_abnormal_response_to | 2.33937131 |
20 | * MP0005000_abnormal_immune_tolerance | 2.32456405 |
21 | * MP0000716_abnormal_immune_system | 2.23439138 |
22 | * MP0002722_abnormal_immune_system | 2.22247276 |
23 | MP0005397_hematopoietic_system_phenotyp | 2.21238451 |
24 | MP0001545_abnormal_hematopoietic_system | 2.21238451 |
25 | * MP0000689_abnormal_spleen_morphology | 2.18936199 |
26 | MP0000703_abnormal_thymus_morphology | 2.18004811 |
27 | MP0003693_abnormal_embryo_hatching | 2.16246942 |
28 | MP0002405_respiratory_system_inflammati | 2.14897942 |
29 | MP0005464_abnormal_platelet_physiology | 2.14478129 |
30 | * MP0002429_abnormal_blood_cell | 2.00844741 |
31 | MP0010155_abnormal_intestine_physiology | 1.98992520 |
32 | MP0010094_abnormal_chromosome_stability | 1.98767295 |
33 | MP0001873_stomach_inflammation | 1.97299402 |
34 | MP0008057_abnormal_DNA_replication | 1.97150066 |
35 | MP0002419_abnormal_innate_immunity | 1.93174610 |
36 | MP0000490_abnormal_crypts_of | 1.92308613 |
37 | MP0002006_tumorigenesis | 1.89934412 |
38 | MP0005075_abnormal_melanosome_morpholog | 1.84207593 |
39 | MP0009278_abnormal_bone_marrow | 1.82660862 |
40 | MP0000465_gastrointestinal_hemorrhage | 1.79804890 |
41 | MP0002148_abnormal_hypersensitivity_rea | 1.77427121 |
42 | MP0003077_abnormal_cell_cycle | 1.74434200 |
43 | MP0003303_peritoneal_inflammation | 1.74092960 |
44 | MP0003724_increased_susceptibility_to | 1.73009314 |
45 | MP0003300_gastrointestinal_ulcer | 1.69488673 |
46 | MP0003111_abnormal_nucleus_morphology | 1.67374891 |
47 | MP0003866_abnormal_defecation | 1.66821625 |
48 | MP0001853_heart_inflammation | 1.65980170 |
49 | MP0005174_abnormal_tail_pigmentation | 1.65773819 |
50 | MP0004957_abnormal_blastocyst_morpholog | 1.63883251 |
51 | MP0010352_gastrointestinal_tract_polyps | 1.56627469 |
52 | MP0004947_skin_inflammation | 1.53181418 |
53 | MP0008260_abnormal_autophagy | 1.51695207 |
54 | MP0001845_abnormal_inflammatory_respons | 1.49340878 |
55 | MP0002019_abnormal_tumor_incidence | 1.44209835 |
56 | MP0006082_CNS_inflammation | 1.43970561 |
57 | MP0000858_altered_metastatic_potential | 1.43323566 |
58 | MP0008058_abnormal_DNA_repair | 1.33814754 |
59 | MP0008007_abnormal_cellular_replicative | 1.28933884 |
60 | MP0002933_joint_inflammation | 1.28785845 |
61 | MP0010307_abnormal_tumor_latency | 1.23709154 |
62 | MP0005058_abnormal_lysosome_morphology | 1.17828783 |
63 | MP0005451_abnormal_body_composition | 1.17050579 |
64 | MP0002998_abnormal_bone_remodeling | 1.16293068 |
65 | MP0002132_abnormal_respiratory_system | 1.10322175 |
66 | MP0001533_abnormal_skeleton_physiology | 1.09720672 |
67 | MP0002095_abnormal_skin_pigmentation | 1.07646415 |
68 | MP0000313_abnormal_cell_death | 1.05873912 |
69 | MP0008469_abnormal_protein_level | 1.03554674 |
70 | MP0002009_preneoplasia | 1.03210863 |
71 | MP0005310_abnormal_salivary_gland | 1.02923103 |
72 | MP0000350_abnormal_cell_proliferation | 0.97834481 |
73 | MP0002277_abnormal_respiratory_mucosa | 0.97636996 |
74 | MP0004883_abnormal_blood_vessel | 0.94883754 |
75 | MP0005023_abnormal_wound_healing | 0.94440602 |
76 | MP0003448_altered_tumor_morphology | 0.94185707 |
77 | MP0003172_abnormal_lysosome_physiology | 0.87513281 |
78 | MP0003075_altered_response_to | 0.86647835 |
79 | MP0005166_decreased_susceptibility_to | 0.86644208 |
80 | MP0004510_myositis | 0.85482890 |
81 | MP0002138_abnormal_hepatobiliary_system | 0.84727320 |
82 | MP0003806_abnormal_nucleotide_metabolis | 0.82021464 |
83 | MP0001348_abnormal_lacrimal_gland | 0.80556234 |
84 | MP0000015_abnormal_ear_pigmentation | 0.80402153 |
85 | MP0003786_premature_aging | 0.76512431 |
86 | MP0001851_eye_inflammation | 0.76028059 |
87 | MP0000477_abnormal_intestine_morphology | 0.74927368 |
88 | MP0000604_amyloidosis | 0.72981079 |
89 | MP0000343_altered_response_to | 0.72244229 |
90 | MP0001730_embryonic_growth_arrest | 0.70663644 |
91 | MP0003656_abnormal_erythrocyte_physiolo | 0.69607975 |
92 | MP0003690_abnormal_glial_cell | 0.69122034 |
93 | MP0005076_abnormal_cell_differentiation | 0.68737280 |
94 | MP0006054_spinal_hemorrhage | 0.68130460 |
95 | MP0003943_abnormal_hepatobiliary_system | 0.66878141 |
96 | MP0005164_abnormal_response_to | 0.66561807 |
97 | MP0009765_abnormal_xenobiotic_induced | 0.65566284 |
98 | MP0002877_abnormal_melanocyte_morpholog | 0.65151640 |
99 | MP0009840_abnormal_foam_cell | 0.64322192 |
100 | MP0003795_abnormal_bone_structure | 0.63570988 |
101 | MP0003566_abnormal_cell_adhesion | 0.63543390 |
102 | MP0001986_abnormal_taste_sensitivity | 0.61991411 |
103 | MP0002080_prenatal_lethality | 0.60663571 |
104 | MP0000249_abnormal_blood_vessel | 0.59513136 |
105 | MP0004381_abnormal_hair_follicle | 0.58732523 |
106 | MP0003045_fibrosis | 0.57570607 |
107 | MP0003183_abnormal_peptide_metabolism | 0.56919526 |
108 | MP0003191_abnormal_cellular_cholesterol | 0.56782649 |
109 | MP0009763_increased_sensitivity_to | 0.56530060 |
110 | MP0002086_abnormal_extraembryonic_tissu | 0.56416063 |
111 | MP0009931_abnormal_skin_appearance | 0.55685377 |
112 | MP0001663_abnormal_digestive_system | 0.54726335 |
113 | MP0008004_abnormal_stomach_pH | 0.54199753 |
114 | MP0005390_skeleton_phenotype | 0.53947112 |
115 | MP0003828_pulmonary_edema | 0.53490940 |
116 | MP0000371_diluted_coat_color | 0.52648026 |
117 | MP0002693_abnormal_pancreas_physiology | 0.52120617 |
118 | MP0001697_abnormal_embryo_size | 0.51316754 |
119 | MP0008874_decreased_physiological_sensi | 0.50628479 |
120 | MP0004130_abnormal_muscle_cell | 0.50538840 |
121 | MP0009764_decreased_sensitivity_to | 0.50131163 |
122 | MP0000358_abnormal_cell_content/ | 0.50052314 |
123 | MP0005621_abnormal_cell_physiology | 0.49370706 |
124 | MP0000609_abnormal_liver_physiology | 0.49231247 |
125 | MP0004185_abnormal_adipocyte_glucose | 0.49046915 |
126 | MP0005381_digestive/alimentary_phenotyp | 0.47322643 |
127 | MP0005319_abnormal_enzyme/_coenzyme | 0.45690296 |
128 | MP0008873_increased_physiological_sensi | 0.42956140 |
129 | MP0004264_abnormal_extraembryonic_tissu | 0.37747160 |
130 | MP0005535_abnormal_body_temperature | 0.37472276 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IgM deficiency (HP:0002850) | 4.82225710 |
2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.76037035 |
3 | Chronic otitis media (HP:0000389) | 4.60053860 |
4 | Thrombocytosis (HP:0001894) | 4.26364236 |
5 | Optic neuritis (HP:0100653) | 4.05402332 |
6 | Retrobulbar optic neuritis (HP:0100654) | 4.05402332 |
7 | Recurrent bronchitis (HP:0002837) | 4.04382559 |
8 | Panhypogammaglobulinemia (HP:0003139) | 4.03860584 |
9 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.98333221 |
10 | Recurrent fungal infections (HP:0002841) | 3.98172554 |
11 | Nasal polyposis (HP:0100582) | 3.89450488 |
12 | Recurrent viral infections (HP:0004429) | 3.89316800 |
13 | Abnormality of T cells (HP:0002843) | 3.81166078 |
14 | Eczematoid dermatitis (HP:0000976) | 3.80516362 |
15 | T lymphocytopenia (HP:0005403) | 3.80081465 |
16 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.78388140 |
17 | Myositis (HP:0100614) | 3.78186069 |
18 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.69366681 |
19 | Petechiae (HP:0000967) | 3.68313655 |
20 | Gastrointestinal infarctions (HP:0005244) | 3.66739716 |
21 | Abnormality of T cell number (HP:0011839) | 3.62981696 |
22 | Recurrent abscess formation (HP:0002722) | 3.59946311 |
23 | Abnormality of T cell physiology (HP:0011840) | 3.59280695 |
24 | Abnormality of the nasal mucosa (HP:0000433) | 3.57856842 |
25 | Abnormal number of erythroid precursors (HP:0012131) | 3.57789481 |
26 | Reticulocytopenia (HP:0001896) | 3.39105303 |
27 | Aplastic anemia (HP:0001915) | 3.38690823 |
28 | Abnormality of B cell number (HP:0010975) | 3.36438664 |
29 | B lymphocytopenia (HP:0010976) | 3.36438664 |
30 | Prolonged bleeding time (HP:0003010) | 3.27348865 |
31 | Urticaria (HP:0001025) | 3.14187865 |
32 | Meningitis (HP:0001287) | 3.13644987 |
33 | Cellulitis (HP:0100658) | 3.11652396 |
34 | IgG deficiency (HP:0004315) | 3.10488809 |
35 | Combined immunodeficiency (HP:0005387) | 3.09762603 |
36 | Gingivitis (HP:0000230) | 3.04015163 |
37 | Autoimmune hemolytic anemia (HP:0001890) | 3.03589257 |
38 | Recurrent cutaneous fungal infections (HP:0011370) | 3.01886083 |
39 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.01886083 |
40 | Severe combined immunodeficiency (HP:0004430) | 3.01884442 |
41 | Pulmonary infiltrates (HP:0002113) | 2.99330912 |
42 | Recurrent bacterial skin infections (HP:0005406) | 2.98245411 |
43 | Keratoconjunctivitis sicca (HP:0001097) | 2.98238537 |
44 | Pustule (HP:0200039) | 2.98061387 |
45 | Gastrointestinal inflammation (HP:0004386) | 2.96707155 |
46 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.86509686 |
47 | Lymphopenia (HP:0001888) | 2.86062206 |
48 | Inflammation of the large intestine (HP:0002037) | 2.82110124 |
49 | Keratoconjunctivitis (HP:0001096) | 2.80168538 |
50 | Lymphoma (HP:0002665) | 2.77540901 |
51 | Thyroiditis (HP:0100646) | 2.70955735 |
52 | Agammaglobulinemia (HP:0004432) | 2.69953357 |
53 | Eosinophilia (HP:0001880) | 2.69046393 |
54 | Granulocytopenia (HP:0001913) | 2.68299704 |
55 | Leukocytosis (HP:0001974) | 2.65117459 |
56 | Basal cell carcinoma (HP:0002671) | 2.64831590 |
57 | Epistaxis (HP:0000421) | 2.64690987 |
58 | Recurrent skin infections (HP:0001581) | 2.61312190 |
59 | Spontaneous hematomas (HP:0007420) | 2.60282085 |
60 | Obstructive lung disease (HP:0006536) | 2.58687150 |
61 | Chronic obstructive pulmonary disease (HP:0006510) | 2.58687150 |
62 | Osteomyelitis (HP:0002754) | 2.57216769 |
63 | Poikiloderma (HP:0001029) | 2.54851956 |
64 | Increased IgE level (HP:0003212) | 2.54199268 |
65 | Abnormality of eosinophils (HP:0001879) | 2.53180561 |
66 | Pallor (HP:0000980) | 2.51807865 |
67 | Abnormality of the fingertips (HP:0001211) | 2.51527541 |
68 | Mediastinal lymphadenopathy (HP:0100721) | 2.46524853 |
69 | Sepsis (HP:0100806) | 2.42935222 |
70 | Vasculitis (HP:0002633) | 2.42004693 |
71 | Hypochromic microcytic anemia (HP:0004840) | 2.41277856 |
72 | Pulmonary embolism (HP:0002204) | 2.39821300 |
73 | Abnormal platelet function (HP:0011869) | 2.37728713 |
74 | Impaired platelet aggregation (HP:0003540) | 2.37728713 |
75 | Stomatitis (HP:0010280) | 2.37692352 |
76 | IgA deficiency (HP:0002720) | 2.36673504 |
77 | Episodic fever (HP:0001954) | 2.34878041 |
78 | Arterial thrombosis (HP:0004420) | 2.33980223 |
79 | Amaurosis fugax (HP:0100576) | 2.32216233 |
80 | Myelodysplasia (HP:0002863) | 2.27325860 |
81 | Anorexia (HP:0002039) | 2.26181911 |
82 | Hypoplasia of the thymus (HP:0000778) | 2.23351530 |
83 | Chest pain (HP:0100749) | 2.21901262 |
84 | Hypergammaglobulinemia (HP:0010702) | 2.21719892 |
85 | Chronic sinusitis (HP:0011109) | 2.19842842 |
86 | Orchitis (HP:0100796) | 2.19101126 |
87 | Encephalitis (HP:0002383) | 2.15989990 |
88 | Bronchitis (HP:0012387) | 2.15573564 |
89 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.15452460 |
90 | Abnormality of the prostate (HP:0008775) | 2.13849951 |
91 | Colitis (HP:0002583) | 2.12761375 |
92 | Abnormality of macrophages (HP:0004311) | 2.12693108 |
93 | Abnormality of the pleura (HP:0002103) | 2.12399708 |
94 | Abnormal platelet volume (HP:0011876) | 2.12304606 |
95 | Gangrene (HP:0100758) | 2.11288260 |
96 | Verrucae (HP:0200043) | 2.10929851 |
97 | Papilloma (HP:0012740) | 2.10929851 |
98 | Increased serum ferritin (HP:0003281) | 2.09679617 |
99 | Gastrointestinal stroma tumor (HP:0100723) | 2.09344072 |
100 | Emphysema (HP:0002097) | 2.08539533 |
101 | Skin rash (HP:0000988) | 2.08061660 |
102 | Viral hepatitis (HP:0006562) | 2.07908415 |
103 | Acute hepatic failure (HP:0006554) | 2.03811251 |
104 | Increased cerebral lipofuscin (HP:0011813) | 2.03764460 |
105 | Joint swelling (HP:0001386) | 2.03217182 |
106 | Hemoptysis (HP:0002105) | 2.03199865 |
107 | Chronic diarrhea (HP:0002028) | 2.03173613 |
108 | Purpura (HP:0000979) | 2.03080479 |
109 | Entropion (HP:0000621) | 2.02635475 |
110 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.01599618 |
111 | Microcytic anemia (HP:0001935) | 2.01284985 |
112 | Slow saccadic eye movements (HP:0000514) | 2.01271081 |
113 | Cheilitis (HP:0100825) | 2.01186811 |
114 | Skin ulcer (HP:0200042) | 2.00276004 |
115 | Glomerulopathy (HP:0100820) | 1.99704534 |
116 | Hepatosplenomegaly (HP:0001433) | 1.99167476 |
117 | Hypochromic anemia (HP:0001931) | 1.98163374 |
118 | Acute myeloid leukemia (HP:0004808) | 1.96298388 |
119 | Increased IgM level (HP:0003496) | 1.96106340 |
120 | Reduced antithrombin III activity (HP:0001976) | 1.95914108 |
121 | Interstitial pulmonary disease (HP:0006530) | 1.94951064 |
122 | Autoimmune thrombocytopenia (HP:0001973) | 1.94322094 |
123 | Gingival bleeding (HP:0000225) | 1.93044250 |
124 | Recurrent sinusitis (HP:0011108) | 1.92329477 |
125 | Macrocytic anemia (HP:0001972) | 1.91707193 |
126 | Abnormality of iron homeostasis (HP:0011031) | 1.89525462 |
127 | Albinism (HP:0001022) | 1.89037356 |
128 | Loss of speech (HP:0002371) | 1.88204956 |
129 | Increased density of long bones (HP:0006392) | 1.85111914 |
130 | Prominent nose (HP:0000448) | 1.84599734 |
131 | Acute lymphatic leukemia (HP:0006721) | 1.83530412 |
132 | Agnosia (HP:0010524) | 1.80144710 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 4.82939975 |
2 | EEF2K | 3.06633919 |
3 | ZAP70 | 2.63423973 |
4 | TXK | 2.62855586 |
5 | PRPF4B | 2.54947624 |
6 | JAK3 | 2.47903822 |
7 | NME2 | 2.25936119 |
8 | BTK | 2.19558011 |
9 | KIT | 2.19531712 |
10 | STK10 | 2.14183035 |
11 | GRK6 | 2.14002247 |
12 | MAP3K10 | 1.99142388 |
13 | TYK2 | 1.90121372 |
14 | FLT3 | 1.89268424 |
15 | TEC | 1.84706365 |
16 | CSF1R | 1.81757156 |
17 | BLK | 1.80393646 |
18 | TESK2 | 1.68630610 |
19 | IKBKE | 1.66516477 |
20 | KDR | 1.65803067 |
21 | SYK | 1.62606494 |
22 | PKN2 | 1.61099551 |
23 | PIM2 | 1.60301520 |
24 | MAP3K13 | 1.57793255 |
25 | ITK | 1.50940066 |
26 | ERN1 | 1.46104092 |
27 | LRRK2 | 1.45541388 |
28 | TGFBR1 | 1.45440915 |
29 | TBK1 | 1.44675413 |
30 | RPS6KB2 | 1.43637281 |
31 | MAP2K3 | 1.40873245 |
32 | IRAK4 | 1.38249638 |
33 | NEK2 | 1.37246026 |
34 | CDC7 | 1.34711779 |
35 | * LCK | 1.29542901 |
36 | TAOK1 | 1.27798167 |
37 | PIM1 | 1.25509079 |
38 | MAP3K3 | 1.22836874 |
39 | TGFBR2 | 1.17757825 |
40 | FES | 1.17553543 |
41 | CDK12 | 1.17368343 |
42 | HCK | 1.13990515 |
43 | RPS6KA4 | 1.13933492 |
44 | FGR | 1.12273092 |
45 | MAP3K1 | 1.10693129 |
46 | IKBKB | 1.09769400 |
47 | CSK | 1.08132063 |
48 | TRIB3 | 1.06363991 |
49 | FGFR4 | 1.04936283 |
50 | WEE1 | 1.03032812 |
51 | NLK | 1.02272016 |
52 | BMPR2 | 1.01755077 |
53 | MAPKAPK3 | 0.97940297 |
54 | TNK2 | 0.97455342 |
55 | SCYL2 | 0.96405349 |
56 | LYN | 0.95001895 |
57 | FGFR3 | 0.92701609 |
58 | CLK1 | 0.90141366 |
59 | MAP3K11 | 0.88922595 |
60 | CDK7 | 0.88485303 |
61 | CDK4 | 0.87803134 |
62 | ACVR1B | 0.87121980 |
63 | SMG1 | 0.87104360 |
64 | MAP3K14 | 0.86566995 |
65 | SIK2 | 0.85813248 |
66 | PRKCQ | 0.85602078 |
67 | TAOK2 | 0.85549351 |
68 | PASK | 0.84191639 |
69 | STK16 | 0.83747707 |
70 | JAK1 | 0.83647567 |
71 | BUB1 | 0.82445709 |
72 | DYRK3 | 0.81620007 |
73 | MARK2 | 0.77722527 |
74 | MATK | 0.77511546 |
75 | PDK1 | 0.77075069 |
76 | MAPK12 | 0.76973622 |
77 | CAMKK2 | 0.76609246 |
78 | TRPM7 | 0.75814488 |
79 | EIF2AK3 | 0.75569291 |
80 | ATR | 0.74952712 |
81 | TAOK3 | 0.73906628 |
82 | STK4 | 0.72419335 |
83 | MAP3K12 | 0.72303608 |
84 | EIF2AK1 | 0.71606452 |
85 | CAMKK1 | 0.69961401 |
86 | MAP3K6 | 0.69076583 |
87 | PAK4 | 0.68331607 |
88 | MAP2K2 | 0.68243786 |
89 | PRKD2 | 0.66994910 |
90 | VRK1 | 0.66502681 |
91 | CDK19 | 0.64805673 |
92 | PTK6 | 0.64394166 |
93 | MAP3K8 | 0.63823338 |
94 | HIPK2 | 0.63571213 |
95 | FYN | 0.61942824 |
96 | PIK3CG | 0.60345890 |
97 | MAPK7 | 0.58116445 |
98 | MAPK4 | 0.58032580 |
99 | EPHB1 | 0.57279279 |
100 | YES1 | 0.56770725 |
101 | SIK1 | 0.55752216 |
102 | CDC42BPA | 0.54862876 |
103 | SIK3 | 0.54147703 |
104 | TLK1 | 0.54040261 |
105 | JAK2 | 0.53062130 |
106 | MARK3 | 0.52519607 |
107 | CHUK | 0.51772835 |
108 | KSR2 | 0.51392739 |
109 | RPS6KA6 | 0.51236952 |
110 | MST4 | 0.50967912 |
111 | AURKB | 0.50076775 |
112 | ALK | 0.48040594 |
113 | GRK7 | 0.47623085 |
114 | MAPK11 | 0.47065433 |
115 | IRAK1 | 0.46957947 |
116 | PDPK1 | 0.45474851 |
117 | MAP2K6 | 0.43306973 |
118 | CDK6 | 0.42849803 |
119 | STK24 | 0.42462311 |
120 | RPS6KC1 | 0.42241496 |
121 | RPS6KL1 | 0.42241496 |
122 | MAPKAPK2 | 0.41842956 |
123 | ADRBK2 | 0.41531020 |
124 | IRAK2 | 0.40956924 |
125 | RIPK4 | 0.39913868 |
126 | MAP3K7 | 0.39588267 |
127 | TESK1 | 0.36538003 |
128 | IRAK3 | 0.34461678 |
129 | PRKG2 | 0.34319160 |
130 | RET | 0.34016081 |
131 | ILK | 0.33929385 |
132 | PLK1 | 0.32102571 |
133 | DYRK1B | 0.31093237 |
134 | MAP3K5 | 0.30117909 |
135 | PRKCH | 0.28963571 |
136 | RAF1 | 0.28946855 |
137 | STK11 | 0.27367482 |
138 | PTK2B | 0.27355775 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.87152731 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.46864662 |
3 | Ribosome_Homo sapiens_hsa03010 | 3.32292068 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 2.61167616 |
5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.38463366 |
6 | Base excision repair_Homo sapiens_hsa03410 | 2.33872688 |
7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.22976915 |
8 | Spliceosome_Homo sapiens_hsa03040 | 1.99467199 |
9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.96317555 |
10 | Measles_Homo sapiens_hsa05162 | 1.96180977 |
11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.95335356 |
12 | Leishmaniasis_Homo sapiens_hsa05140 | 1.90465033 |
13 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.90183210 |
14 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.88757511 |
15 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.87237334 |
16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.85512306 |
17 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.85462609 |
18 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.81536320 |
19 | Homologous recombination_Homo sapiens_hsa03440 | 1.74292570 |
20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.69355338 |
21 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.69037695 |
22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.66631064 |
23 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.59092591 |
24 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.55806513 |
25 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.49549910 |
26 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.49319179 |
27 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.47905940 |
28 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.47196570 |
29 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.40489819 |
30 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.37592650 |
31 | Cell cycle_Homo sapiens_hsa04110 | 1.33224950 |
32 | RNA transport_Homo sapiens_hsa03013 | 1.31668645 |
33 | Shigellosis_Homo sapiens_hsa05131 | 1.30887000 |
34 | Allograft rejection_Homo sapiens_hsa05330 | 1.23605663 |
35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.21076158 |
36 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.19181491 |
37 | Proteasome_Homo sapiens_hsa03050 | 1.17567174 |
38 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.16722146 |
39 | Hepatitis B_Homo sapiens_hsa05161 | 1.15816002 |
40 | Apoptosis_Homo sapiens_hsa04210 | 1.15631635 |
41 | RNA degradation_Homo sapiens_hsa03018 | 1.14963291 |
42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.13246392 |
43 | Legionellosis_Homo sapiens_hsa05134 | 1.11512552 |
44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.11173921 |
45 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.07058753 |
46 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.05477704 |
47 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.05417797 |
48 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.05287141 |
49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.05232482 |
50 | RNA polymerase_Homo sapiens_hsa03020 | 1.04478067 |
51 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.03519933 |
52 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.99978831 |
53 | Influenza A_Homo sapiens_hsa05164 | 0.99802934 |
54 | HTLV-I infection_Homo sapiens_hsa05166 | 0.99032934 |
55 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.98764816 |
56 | Other glycan degradation_Homo sapiens_hsa00511 | 0.98728214 |
57 | Platelet activation_Homo sapiens_hsa04611 | 0.97993547 |
58 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.96974973 |
59 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.96843187 |
60 | Asthma_Homo sapiens_hsa05310 | 0.96249719 |
61 | Viral myocarditis_Homo sapiens_hsa05416 | 0.96222132 |
62 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.93790639 |
63 | Phagosome_Homo sapiens_hsa04145 | 0.91228870 |
64 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.86773109 |
65 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.83702435 |
66 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.83220295 |
67 | Sulfur relay system_Homo sapiens_hsa04122 | 0.81689410 |
68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.78914339 |
69 | Thyroid cancer_Homo sapiens_hsa05216 | 0.78699182 |
70 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.77263337 |
71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.76771291 |
72 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.75916705 |
73 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.75191096 |
74 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.75111168 |
75 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.73724371 |
76 | Colorectal cancer_Homo sapiens_hsa05210 | 0.73713084 |
77 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.72493160 |
78 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.69755435 |
79 | Tuberculosis_Homo sapiens_hsa05152 | 0.69036473 |
80 | Lysosome_Homo sapiens_hsa04142 | 0.68359430 |
81 | Pertussis_Homo sapiens_hsa05133 | 0.68121483 |
82 | Malaria_Homo sapiens_hsa05144 | 0.67932303 |
83 | Salmonella infection_Homo sapiens_hsa05132 | 0.65730477 |
84 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.64820467 |
85 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.64673154 |
86 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.64654981 |
87 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.64375477 |
88 | Endocytosis_Homo sapiens_hsa04144 | 0.63235412 |
89 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.63232744 |
90 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63031274 |
91 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.59718222 |
92 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.59489297 |
93 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.58520649 |
94 | Basal transcription factors_Homo sapiens_hsa03022 | 0.56339250 |
95 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.55021764 |
96 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53856096 |
97 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.52831448 |
98 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.52723485 |
99 | Hepatitis C_Homo sapiens_hsa05160 | 0.52249840 |
100 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.51867025 |
101 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.51807209 |
102 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51425311 |
103 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.50943296 |
104 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50806743 |
105 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.48255291 |
106 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.48056889 |
107 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47633205 |
108 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.47350901 |
109 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.46629168 |
110 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.46440034 |
111 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.44733519 |
112 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.44661078 |
113 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.41927135 |
114 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41835494 |
115 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.41144384 |
116 | Endometrial cancer_Homo sapiens_hsa05213 | 0.40683222 |
117 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.40584418 |
118 | Purine metabolism_Homo sapiens_hsa00230 | 0.39402588 |
119 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38350434 |
120 | Galactose metabolism_Homo sapiens_hsa00052 | 0.36916604 |
121 | Insulin resistance_Homo sapiens_hsa04931 | 0.33129390 |
122 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.33101859 |
123 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31685194 |
124 | Pathways in cancer_Homo sapiens_hsa05200 | 0.31594400 |
125 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.31556604 |
126 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.30706707 |
127 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.29860826 |
128 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.29270050 |
129 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.27646879 |
130 | Amoebiasis_Homo sapiens_hsa05146 | 0.26327971 |
131 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.22107258 |
132 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.21049611 |
133 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.20187716 |
134 | Prostate cancer_Homo sapiens_hsa05215 | 0.19158544 |
135 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.17015819 |