DEK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.74503074
2DNA strand elongation involved in DNA replication (GO:0006271)5.21454307
3establishment of integrated proviral latency (GO:0075713)5.15575651
4telomere maintenance via semi-conservative replication (GO:0032201)5.00026586
5DNA strand elongation (GO:0022616)4.95572398
6DNA replication initiation (GO:0006270)4.95052989
7kinetochore organization (GO:0051383)4.91429609
8protein localization to kinetochore (GO:0034501)4.79033707
9mitotic recombination (GO:0006312)4.64712889
10telomere maintenance via recombination (GO:0000722)4.61575270
11DNA replication checkpoint (GO:0000076)4.57827230
12nuclear pore complex assembly (GO:0051292)4.43470470
13mitotic chromosome condensation (GO:0007076)4.39155069
14chromatin remodeling at centromere (GO:0031055)4.39149066
15nuclear pore organization (GO:0006999)4.37870427
16CENP-A containing nucleosome assembly (GO:0034080)4.35556504
17DNA ligation (GO:0006266)4.33894123
18mitotic sister chromatid cohesion (GO:0007064)4.31595754
19protein localization to chromosome, centromeric region (GO:0071459)4.26348278
20DNA replication-independent nucleosome organization (GO:0034724)4.05849285
21DNA replication-independent nucleosome assembly (GO:0006336)4.05849285
22sister chromatid segregation (GO:0000819)4.04918962
23kinetochore assembly (GO:0051382)4.04719647
24regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.01186251
25DNA topological change (GO:0006265)3.99232018
26mitotic sister chromatid segregation (GO:0000070)3.99125485
27telomere maintenance via telomere lengthening (GO:0010833)3.98781212
28meiotic chromosome segregation (GO:0045132)3.98033256
29mitotic metaphase plate congression (GO:0007080)3.97937621
30regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.96790433
31nucleotide-excision repair, DNA gap filling (GO:0006297)3.95985706
32ribosomal small subunit assembly (GO:0000028)3.93488549
33establishment of viral latency (GO:0019043)3.92420670
34attachment of spindle microtubules to kinetochore (GO:0008608)3.89728823
35DNA replication-dependent nucleosome organization (GO:0034723)3.81132617
36DNA replication-dependent nucleosome assembly (GO:0006335)3.81132617
37mitotic nuclear envelope disassembly (GO:0007077)3.80781829
38metaphase plate congression (GO:0051310)3.72802899
39DNA duplex unwinding (GO:0032508)3.70877580
40DNA geometric change (GO:0032392)3.70226487
41regulation of DNA endoreduplication (GO:0032875)3.65824149
42histone exchange (GO:0043486)3.65028720
43negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.64525180
44non-recombinational repair (GO:0000726)3.63956160
45double-strand break repair via nonhomologous end joining (GO:0006303)3.63956160
46regulation of mitotic spindle organization (GO:0060236)3.63786822
47regulation of centriole replication (GO:0046599)3.59513296
48regulation of sister chromatid segregation (GO:0033045)3.54798057
49regulation of mitotic sister chromatid separation (GO:0010965)3.54798057
50regulation of mitotic sister chromatid segregation (GO:0033047)3.54798057
51membrane disassembly (GO:0030397)3.51463075
52nuclear envelope disassembly (GO:0051081)3.51463075
53DNA packaging (GO:0006323)3.50550813
54chromatin assembly or disassembly (GO:0006333)3.48108203
55translesion synthesis (GO:0019985)3.47772191
56mitotic spindle checkpoint (GO:0071174)3.47015013
57mitotic spindle assembly checkpoint (GO:0007094)3.46573891
58establishment of chromosome localization (GO:0051303)3.45337222
59purine nucleobase biosynthetic process (GO:0009113)3.43190036
60maturation of SSU-rRNA (GO:0030490)3.40599014
61pore complex assembly (GO:0046931)3.40079216
62negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.38948721
63viral transcription (GO:0019083)3.36337190
64translational termination (GO:0006415)3.34743665
65negative regulation of RNA splicing (GO:0033119)3.32072110
66telomere maintenance (GO:0000723)3.29533072
67IMP biosynthetic process (GO:0006188)3.28607116
68DNA conformation change (GO:0071103)3.28382749
69regulation of spindle organization (GO:0090224)3.26995759
70telomere organization (GO:0032200)3.26588981
71ribosomal large subunit biogenesis (GO:0042273)3.22229682
72regulation of histone H3-K9 methylation (GO:0051570)3.21189812
73maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.19589466
74ribosome assembly (GO:0042255)3.19521154
75regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.19515477
76ATP-dependent chromatin remodeling (GO:0043044)3.19137197
77protein localization to chromosome (GO:0034502)3.18166015
78regulation of sister chromatid cohesion (GO:0007063)3.17317875
79chromosome segregation (GO:0007059)3.17071962
80folic acid-containing compound biosynthetic process (GO:0009396)3.14766904
81positive regulation of chromosome segregation (GO:0051984)3.13893650
82negative regulation of DNA-dependent DNA replication (GO:2000104)3.13706932
83dosage compensation (GO:0007549)3.11956192
84chromosome condensation (GO:0030261)3.11449260
85formation of translation preinitiation complex (GO:0001731)3.09305329
86regulation of nuclear cell cycle DNA replication (GO:0033262)3.09017800
87postreplication repair (GO:0006301)3.08587002
88DNA synthesis involved in DNA repair (GO:0000731)3.07514308
89negative regulation of mRNA processing (GO:0050686)3.07007878
90mismatch repair (GO:0006298)3.06847898
91regulation of chromosome segregation (GO:0051983)3.06490845
92deoxyribonucleotide biosynthetic process (GO:0009263)3.06015165
93mitotic cell cycle (GO:0000278)3.05877861
94regulation of centrosome cycle (GO:0046605)3.05771677
95mitotic G2 DNA damage checkpoint (GO:0007095)3.04959036
96spindle checkpoint (GO:0031577)3.04339738
97chromatin assembly (GO:0031497)3.02267890
98positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.01774375
99positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.01774375
100positive regulation of mitotic sister chromatid separation (GO:1901970)3.01774375
101nucleobase biosynthetic process (GO:0046112)3.01107752
102regulation of mitotic metaphase/anaphase transition (GO:0030071)3.00375015
103nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.98761852
104spindle assembly checkpoint (GO:0071173)2.98557150
105IMP metabolic process (GO:0046040)2.98106980
106heterochromatin organization (GO:0070828)2.97081897
107regulation of double-strand break repair via homologous recombination (GO:0010569)2.96798569
108negative regulation of chromosome segregation (GO:0051985)2.95142514
109translational elongation (GO:0006414)2.94803219
110mitotic DNA integrity checkpoint (GO:0044774)2.94695545
111mitotic G2/M transition checkpoint (GO:0044818)2.93651134
112ribosomal small subunit biogenesis (GO:0042274)2.93372967
113regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.92862839
114negative regulation of mitotic sister chromatid segregation (GO:0033048)2.92661660
115negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.92661660
116negative regulation of sister chromatid segregation (GO:0033046)2.92661660
117negative regulation of mitotic sister chromatid separation (GO:2000816)2.92661660
118DNA deamination (GO:0045006)2.91857111
119DNA double-strand break processing (GO:0000729)2.91605128
120regulation of helicase activity (GO:0051095)2.91602593
121translational initiation (GO:0006413)2.89582283
122DNA strand renaturation (GO:0000733)2.87921877

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.52965423
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.58428279
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.69947998
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.69860880
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.34680595
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.75845555
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.56966757
8* E2F1_21310950_ChIP-Seq_MCF-7_Human2.51914829
9AR_21909140_ChIP-Seq_LNCAP_Human2.48473104
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.43862384
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.21258205
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.20873146
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.20513083
14NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13597929
15MYC_22102868_ChIP-Seq_BL_Human2.03775990
16XRN2_22483619_ChIP-Seq_HELA_Human2.00233746
17E2F7_22180533_ChIP-Seq_HELA_Human11.6561208
18* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.97660692
19CREB1_15753290_ChIP-ChIP_HEK293T_Human1.95535293
20MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.91714936
21ELF1_17652178_ChIP-ChIP_JURKAT_Human1.90623241
22VDR_23849224_ChIP-Seq_CD4+_Human1.87406468
23GABP_17652178_ChIP-ChIP_JURKAT_Human1.85202822
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.82952678
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.81143927
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.77995711
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.73706314
28FOXP3_21729870_ChIP-Seq_TREG_Human1.69758896
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.68805788
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.67341551
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64831611
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61404930
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.58833732
34CIITA_25753668_ChIP-Seq_RAJI_Human1.58368993
35* TTF2_22483619_ChIP-Seq_HELA_Human1.57463868
36TP63_19390658_ChIP-ChIP_HaCaT_Human1.56941993
37* ELK1_19687146_ChIP-ChIP_HELA_Human1.55016643
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.53413567
39* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.53011793
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.52900537
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52343227
42JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.51875777
43HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.51860490
44DCP1A_22483619_ChIP-Seq_HELA_Human1.51689388
45VDR_21846776_ChIP-Seq_THP-1_Human1.40699583
46* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40373929
47KDM5A_27292631_Chip-Seq_BREAST_Human1.36852209
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.36545332
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.36232295
50GABP_19822575_ChIP-Seq_HepG2_Human1.35948264
51NANOG_18555785_ChIP-Seq_MESCs_Mouse1.32930965
52* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31870378
53SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.29434977
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.26507654
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26249149
56E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.21991277
57THAP11_20581084_ChIP-Seq_MESCs_Mouse1.18438660
58NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.14318043
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12995178
60SPI1_23547873_ChIP-Seq_NB4_Human1.10342868
61HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09356397
62CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09142018
63SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.05803889
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.05739188
65SCL_19346495_ChIP-Seq_HPC-7_Human1.05673359
66TFEB_21752829_ChIP-Seq_HELA_Human1.05294291
67FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03823502
68POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.03316577
69KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02976490
70IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.02746419
71NANOG_16153702_ChIP-ChIP_HESCs_Human1.02170758
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01905445
73MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.01662226
74SOX17_20123909_ChIP-Seq_XEN_Mouse1.00118162
75RBPJ_22232070_ChIP-Seq_NCS_Mouse0.99810052
76SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.99129946
77MYB_21317192_ChIP-Seq_ERMYB_Mouse0.98156124
78GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97942006
79E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.96763185
80SOX2_18555785_ChIP-Seq_MESCs_Mouse0.96716739
81NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.96520991
82* MYB_26560356_Chip-Seq_TH2_Human0.95618062
83MYB_26560356_Chip-Seq_TH1_Human0.95503328
84* NANOG_21062744_ChIP-ChIP_HESCs_Human0.95353848
85STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94884666
86MYC_18940864_ChIP-ChIP_HL60_Human0.94597165
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.94384855
88SOX2_16153702_ChIP-ChIP_HESCs_Human0.93465835
89CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93399010
90ESR1_15608294_ChIP-ChIP_MCF-7_Human0.92909121
91POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.91832274
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90833780
93CHD1_26751641_Chip-Seq_LNCaP_Human0.90077633
94SALL1_21062744_ChIP-ChIP_HESCs_Human0.89726571
95* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88923060
96TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.88023549
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.87817638
98TCF3_18692474_ChIP-Seq_MEFs_Mouse0.86940091
99* MAF_26560356_Chip-Seq_TH1_Human0.86507766
100CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86384640
101UTX_26944678_Chip-Seq_JUKART_Human0.85845153
102SRF_21415370_ChIP-Seq_HL-1_Mouse0.85675981
103FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.84339979
104* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81069717
105CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.80072923
106NOTCH1_21737748_ChIP-Seq_TLL_Human0.79893885
107EWS_26573619_Chip-Seq_HEK293_Human0.79313387
108SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.78842069
109RUNX1_22412390_ChIP-Seq_EML_Mouse0.77573616
110PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.77550926
111BRD4_27068464_Chip-Seq_AML-cells_Mouse0.77476460
112YY1_21170310_ChIP-Seq_MESCs_Mouse0.77400195
113* STAT4_19710469_ChIP-ChIP_TH1__Mouse0.77174981
114* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.76546784
115* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.75762053
116HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.74247412
117POU5F1_16153702_ChIP-ChIP_HESCs_Human0.74084121
118BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.72564714
119SOX2_18692474_ChIP-Seq_MEFs_Mouse0.67236359
120DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.66590630

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.79445155
2MP0003693_abnormal_embryo_hatching4.48047538
3MP0008057_abnormal_DNA_replication4.08118954
4MP0003111_abnormal_nucleus_morphology4.07059669
5MP0004957_abnormal_blastocyst_morpholog3.73750690
6MP0003077_abnormal_cell_cycle3.71839857
7MP0008058_abnormal_DNA_repair2.85624230
8MP0002396_abnormal_hematopoietic_system2.83347468
9MP0010352_gastrointestinal_tract_polyps2.54677345
10MP0009697_abnormal_copulation2.54508891
11MP0008007_abnormal_cellular_replicative2.45307426
12MP0008932_abnormal_embryonic_tissue2.24385811
13MP0010307_abnormal_tumor_latency2.22172851
14MP0003123_paternal_imprinting2.20242382
15MP0008877_abnormal_DNA_methylation2.19556030
16MP0000350_abnormal_cell_proliferation2.11819791
17MP0004808_abnormal_hematopoietic_stem1.98683836
18MP0001730_embryonic_growth_arrest1.98015404
19MP0000490_abnormal_crypts_of1.95373553
20MP0009379_abnormal_foot_pigmentation1.91606905
21MP0003941_abnormal_skin_development1.70248439
22MP0006054_spinal_hemorrhage1.63680024
23MP0005076_abnormal_cell_differentiation1.61426689
24MP0001545_abnormal_hematopoietic_system1.58966129
25MP0005397_hematopoietic_system_phenotyp1.58966129
26MP0003763_abnormal_thymus_physiology1.57666146
27MP0001672_abnormal_embryogenesis/_devel1.57132452
28MP0005380_embryogenesis_phenotype1.57132452
29MP0001697_abnormal_embryo_size1.55371045
30MP0002398_abnormal_bone_marrow1.50646664
31* MP0002019_abnormal_tumor_incidence1.49922577
32MP0003786_premature_aging1.49667486
33MP0003718_maternal_effect1.46074259
34MP0003567_abnormal_fetal_cardiomyocyte1.45796024
35MP0003121_genomic_imprinting1.45786989
36MP0003984_embryonic_growth_retardation1.45052674
37MP0002697_abnormal_eye_size1.44455203
38MP0004197_abnormal_fetal_growth/weight/1.42889777
39MP0000703_abnormal_thymus_morphology1.42535821
40MP0002088_abnormal_embryonic_growth/wei1.41872757
41MP0000313_abnormal_cell_death1.41719190
42MP0002086_abnormal_extraembryonic_tissu1.38512272
43MP0002080_prenatal_lethality1.37249562
44MP0002085_abnormal_embryonic_tissue1.34802673
45MP0001286_abnormal_eye_development1.34263124
46MP0002722_abnormal_immune_system1.30472532
47MP0002084_abnormal_developmental_patter1.29756549
48MP0009333_abnormal_splenocyte_physiolog1.27654447
49MP0002166_altered_tumor_susceptibility1.26922261
50MP0009278_abnormal_bone_marrow1.26328078
51MP0000689_abnormal_spleen_morphology1.24213459
52MP0002006_tumorigenesis1.20351936
53MP0010030_abnormal_orbit_morphology1.18363936
54MP0001835_abnormal_antigen_presentation1.10420639
55MP0002429_abnormal_blood_cell1.09963230
56MP0003890_abnormal_embryonic-extraembry1.08717226
57MP0001800_abnormal_humoral_immune1.07070734
58MP0001293_anophthalmia1.06373069
59MP0002009_preneoplasia1.05902977
60MP0004185_abnormal_adipocyte_glucose1.03343930
61MP0001346_abnormal_lacrimal_gland1.02452473
62MP0002111_abnormal_tail_morphology1.01588027
63MP0000716_abnormal_immune_system1.01535243
64MP0009053_abnormal_anal_canal0.99560990
65MP0003806_abnormal_nucleotide_metabolis0.98780760
66MP0002210_abnormal_sex_determination0.95973972
67MP0002938_white_spotting0.95601539
68MP0003221_abnormal_cardiomyocyte_apopto0.94006113
69MP0000685_abnormal_immune_system0.93156408
70MP0002452_abnormal_antigen_presenting0.92526023
71MP0002420_abnormal_adaptive_immunity0.92423908
72MP0001819_abnormal_immune_cell0.90887205
73MP0005671_abnormal_response_to0.85752437
74MP0005174_abnormal_tail_pigmentation0.85418025
75MP0004147_increased_porphyrin_level0.84555038
76MP0000858_altered_metastatic_potential0.84510476
77MP0001915_intracranial_hemorrhage0.84492708
78MP0003656_abnormal_erythrocyte_physiolo0.84295791
79MP0001145_abnormal_male_reproductive0.84147116
80MP0002405_respiratory_system_inflammati0.83671118
81MP0002095_abnormal_skin_pigmentation0.83081297
82MP0002233_abnormal_nose_morphology0.82336304
83MP0005501_abnormal_skin_physiology0.82082819
84MP0000537_abnormal_urethra_morphology0.80869531
85MP0003315_abnormal_perineum_morphology0.80416123
86MP0009672_abnormal_birth_weight0.80175994
87MP0001853_heart_inflammation0.79496199
88MP0003705_abnormal_hypodermis_morpholog0.78522400
89MP0005075_abnormal_melanosome_morpholog0.77814522
90MP0002723_abnormal_immune_serum0.76806764
91MP0003755_abnormal_palate_morphology0.76015315
92MP0000358_abnormal_cell_content/0.75498435
93MP0003861_abnormal_nervous_system0.74464555
94MP0001299_abnormal_eye_distance/0.74213625
95MP0000465_gastrointestinal_hemorrhage0.73195943
96MP0003950_abnormal_plasma_membrane0.73189698
97MP0002877_abnormal_melanocyte_morpholog0.72408921
98MP0001873_stomach_inflammation0.71742486
99MP0000653_abnormal_sex_gland0.71383166
100MP0003448_altered_tumor_morphology0.71363539
101MP0001119_abnormal_female_reproductive0.71038390
102MP0009703_decreased_birth_body0.70652582
103MP0000432_abnormal_head_morphology0.70057153
104MP0002234_abnormal_pharynx_morphology0.69737803
105MP0010155_abnormal_intestine_physiology0.69280285
106MP0000477_abnormal_intestine_morphology0.69037342
107MP0003436_decreased_susceptibility_to0.68709184
108MP0001929_abnormal_gametogenesis0.68641981
109MP0003566_abnormal_cell_adhesion0.68244452
110MP0002092_abnormal_eye_morphology0.67130037
111MP0003937_abnormal_limbs/digits/tail_de0.66449380
112MP0003935_abnormal_craniofacial_develop0.66140839
113MP0005025_abnormal_response_to0.65939973
114MP0002075_abnormal_coat/hair_pigmentati0.65809762
115MP0003385_abnormal_body_wall0.65638385
116MP0008789_abnormal_olfactory_epithelium0.65559061
117MP0005000_abnormal_immune_tolerance0.65273948
118MP0005023_abnormal_wound_healing0.64738647
119MP0000383_abnormal_hair_follicle0.64520665
120MP0001188_hyperpigmentation0.63490088
121MP0003787_abnormal_imprinting0.63485720
122MP0005384_cellular_phenotype0.63473740
123MP0005621_abnormal_cell_physiology0.63253527
124MP0000428_abnormal_craniofacial_morphol0.62897788
125MP0006292_abnormal_olfactory_placode0.62167405
126MP0010234_abnormal_vibrissa_follicle0.61557211
127MP0003136_yellow_coat_color0.60974837
128MP0006035_abnormal_mitochondrial_morpho0.60741936
129MP0000762_abnormal_tongue_morphology0.60727070
130MP0003115_abnormal_respiratory_system0.60611584
131MP0002796_impaired_skin_barrier0.59040605
132MP0002114_abnormal_axial_skeleton0.58543241
133MP0001881_abnormal_mammary_gland0.58229732
134MP0000566_synostosis0.56453493
135MP0000049_abnormal_middle_ear0.55285617
136MP0005391_vision/eye_phenotype0.55222492
137MP0003943_abnormal_hepatobiliary_system0.54671985
138MP0001727_abnormal_embryo_implantation0.54669548
139MP0000627_abnormal_mammary_gland0.54075461
140MP0003699_abnormal_female_reproductive0.53279386
141MP0001340_abnormal_eyelid_morphology0.53003681
142MP0002081_perinatal_lethality0.51589133

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.32888157
2Reticulocytopenia (HP:0001896)4.24429147
3Birth length less than 3rd percentile (HP:0003561)4.12500851
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.88341971
5Abnormality of chromosome stability (HP:0003220)3.87733438
6Volvulus (HP:0002580)3.60879984
7Abnormality of cells of the erythroid lineage (HP:0012130)3.48046258
8Abnormal number of erythroid precursors (HP:0012131)3.39595509
9Selective tooth agenesis (HP:0001592)3.30148300
10Colon cancer (HP:0003003)3.27921552
11Abnormality of the preputium (HP:0100587)3.06350134
12Cortical dysplasia (HP:0002539)3.01822566
13Meckel diverticulum (HP:0002245)3.01609728
14Medulloblastoma (HP:0002885)2.98352829
15Aplasia/Hypoplasia of the sacrum (HP:0008517)2.97594996
16Increased nuchal translucency (HP:0010880)2.93488847
17Abnormal number of incisors (HP:0011064)2.89865226
18Abnormality of the ileum (HP:0001549)2.87764315
19Myelodysplasia (HP:0002863)2.87127321
20Aplasia/Hypoplasia of the uvula (HP:0010293)2.84360515
21Ectopic kidney (HP:0000086)2.76982249
22Patellar aplasia (HP:0006443)2.75421991
23Oral leukoplakia (HP:0002745)2.74422290
24Breast hypoplasia (HP:0003187)2.66452973
25Small intestinal stenosis (HP:0012848)2.64480340
26Duodenal stenosis (HP:0100867)2.64480340
27IgM deficiency (HP:0002850)2.63449762
28Proximal placement of thumb (HP:0009623)2.58864432
29Agnosia (HP:0010524)2.56284952
30Aplasia/Hypoplasia of the patella (HP:0006498)2.55335734
31Multiple enchondromatosis (HP:0005701)2.53059436
32Rhabdomyosarcoma (HP:0002859)2.51483372
33Absent thumb (HP:0009777)2.50498282
34Pallor (HP:0000980)2.49006243
35Deviation of the thumb (HP:0009603)2.48875742
36Short 4th metacarpal (HP:0010044)2.48703103
37Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.48703103
38High pitched voice (HP:0001620)2.47843748
39Basal cell carcinoma (HP:0002671)2.47455269
4011 pairs of ribs (HP:0000878)2.45282510
41Thrombocytosis (HP:0001894)2.43364341
42Ependymoma (HP:0002888)2.42713196
43Abnormality of the heme biosynthetic pathway (HP:0010472)2.39080904
44Aplastic anemia (HP:0001915)2.37607110
45Lymphoma (HP:0002665)2.37349872
46Microvesicular hepatic steatosis (HP:0001414)2.33472821
47Prominent nose (HP:0000448)2.33006895
48Abnormality of the fingertips (HP:0001211)2.32620808
49Macrocytic anemia (HP:0001972)2.26494123
50Facial hemangioma (HP:0000329)2.25821786
51Abnormality of the carotid arteries (HP:0005344)2.23749135
52Absent radius (HP:0003974)2.22217850
53Duplication of thumb phalanx (HP:0009942)2.22084207
54Atresia of the external auditory canal (HP:0000413)2.21908644
55Choanal atresia (HP:0000453)2.20812259
56Squamous cell carcinoma (HP:0002860)2.19996327
57Degeneration of anterior horn cells (HP:0002398)2.19570712
58Abnormality of the anterior horn cell (HP:0006802)2.19570712
59Abnormality of the duodenum (HP:0002246)2.18492195
60Impulsivity (HP:0100710)2.17713807
61Abnormal lung lobation (HP:0002101)2.17403198
62Cafe-au-lait spot (HP:0000957)2.17384805
63Clubbing of toes (HP:0100760)2.13975076
64Bone marrow hypocellularity (HP:0005528)2.13551472
65Sloping forehead (HP:0000340)2.11637760
66Acute myeloid leukemia (HP:0004808)2.09997848
67Arteriovenous malformation (HP:0100026)2.09769384
68Duplicated collecting system (HP:0000081)2.09636957
69Premature graying of hair (HP:0002216)2.09058613
70Abnormality of reticulocytes (HP:0004312)2.08473053
71Overlapping toe (HP:0001845)2.07659033
72Long eyelashes (HP:0000527)2.06144684
73Short middle phalanx of the 5th finger (HP:0004220)2.05140535
74Neoplasm of the pancreas (HP:0002894)2.05100364
75Acute lymphatic leukemia (HP:0006721)2.04783931
76Embryonal neoplasm (HP:0002898)2.04349471
77Aplasia involving forearm bones (HP:0009822)2.04125593
78Absent forearm bone (HP:0003953)2.04125593
79Tracheoesophageal fistula (HP:0002575)2.03832222
80Progressive muscle weakness (HP:0003323)2.01187594
81Abnormality of cochlea (HP:0000375)1.97654453
82Progressive external ophthalmoplegia (HP:0000590)1.97280391
83Amaurosis fugax (HP:0100576)1.96432149
84Abnormality of DNA repair (HP:0003254)1.94980014
85Recurrent viral infections (HP:0004429)1.94039331
86Facial cleft (HP:0002006)1.92926020
87Abnormality of the calcaneus (HP:0008364)1.91797703
88Triphalangeal thumb (HP:0001199)1.91171898
89Abnormality of T cells (HP:0002843)1.90817379
90Abnormality of the renal collecting system (HP:0004742)1.90663652
91T lymphocytopenia (HP:0005403)1.89512951
92Nephroblastoma (Wilms tumor) (HP:0002667)1.89217270
93High anterior hairline (HP:0009890)1.87223192
94Short thumb (HP:0009778)1.86398645
95Deep philtrum (HP:0002002)1.84631503
96Cellular immunodeficiency (HP:0005374)1.83784762
97Poikiloderma (HP:0001029)1.82253700
98Abnormality of B cell number (HP:0010975)1.80806323
99B lymphocytopenia (HP:0010976)1.80806323
100Horseshoe kidney (HP:0000085)1.80289797
101Neoplasm of striated muscle (HP:0009728)1.80134458
102Aplasia/Hypoplasia of the sternum (HP:0006714)1.76869459
103Asplenia (HP:0001746)1.76051659
104Abnormality of T cell number (HP:0011839)1.75928625
105Septo-optic dysplasia (HP:0100842)1.75286743
106Abnormality of T cell physiology (HP:0011840)1.74755189
107Biliary tract neoplasm (HP:0100574)1.74086423
108Abnormality of the septum pellucidum (HP:0007375)1.73452087
109Neoplasm of the colon (HP:0100273)1.73194512
110Embryonal renal neoplasm (HP:0011794)1.72995055
111Poikilocytosis (HP:0004447)1.72685589
112Carpal bone hypoplasia (HP:0001498)1.72624776
113Cutis marmorata (HP:0000965)1.72282390
114IgG deficiency (HP:0004315)1.72219821
115Broad palm (HP:0001169)1.71822195
116Missing ribs (HP:0000921)1.71314744
117Cleft eyelid (HP:0000625)1.71247192
118Blepharitis (HP:0000498)1.69803847
119Abnormality of chromosome segregation (HP:0002916)1.69492963
120Pancytopenia (HP:0001876)1.66546208
121Gastrointestinal carcinoma (HP:0002672)1.66536188
122Malignant gastrointestinal tract tumors (HP:0006749)1.66536188
123Microglossia (HP:0000171)1.63566662
124Obsessive-compulsive behavior (HP:0000722)1.58098233
125Uterine neoplasm (HP:0010784)1.55888047
126Flared metaphyses (HP:0003015)1.55051252
127Ovarian neoplasm (HP:0100615)1.54791634
128Neoplasm of the small intestine (HP:0100833)1.54677483
129Overriding aorta (HP:0002623)1.53839330
130Absent septum pellucidum (HP:0001331)1.53304567
131Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.52608387
132Neuroblastoma (HP:0003006)1.52608387
133Primitive neuroectodermal tumor (HP:0030065)1.52608387
134Neuroblastic tumors (HP:0004376)1.52608387
135Abnormality of the labia minora (HP:0012880)1.52142363
136Cystic hygroma (HP:0000476)1.50504308
137Partial agenesis of the corpus callosum (HP:0001338)1.50082079
138Abnormality of methionine metabolism (HP:0010901)1.49881225
139Megaloblastic anemia (HP:0001889)1.49824778

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.69549455
2WEE13.64052019
3NEK23.13902446
4TAF13.00723600
5BUB12.97938619
6VRK22.95113249
7TTK2.56494594
8EIF2AK12.56166455
9ACVR1B2.55699341
10SRPK12.34734400
11CDK122.18726648
12MKNK12.16717223
13ATR2.04035750
14PLK11.92028021
15BRSK21.86592033
16RPS6KA41.83654756
17NEK11.76354464
18SMG11.75298141
19* AURKB1.73982584
20STK41.72207601
21CDK41.70699888
22PLK41.69899369
23STK101.66376254
24VRK11.65143571
25CDK71.64996367
26MKNK21.62060446
27CLK11.61202618
28TLK11.56947292
29EEF2K1.55989300
30MAP3K101.55744152
31DYRK31.52555156
32RPS6KB21.49158426
33PASK1.48587049
34CHEK21.45375778
35CDK61.42522841
36PLK31.36730964
37NME21.33083132
38MAP4K11.33007215
39CHEK11.32685153
40MAP3K81.32213769
41TGFBR11.26827054
42TESK21.26787252
43TSSK61.26452170
44SCYL21.19379642
45BRSK11.17386952
46PNCK1.16183126
47CCNB11.15739648
48PIM11.12145747
49ATM1.12023185
50BRD41.05609364
51STK31.04801457
52EIF2AK31.01060466
53MELK0.97738351
54PKN20.96289144
55FLT30.94748482
56LRRK20.93404194
57BRAF0.92738897
58CDK20.92174162
59MAP3K90.92116708
60PAK40.86044848
61AURKA0.85094925
62MST40.83764730
63MAP2K30.81472101
64CDK80.81001011
65TEC0.77972178
66BTK0.74934928
67ZAK0.73676726
68STK160.72204951
69CDK10.71269883
70PBK0.69276497
71LATS20.66646853
72CSNK2A20.61950161
73JAK30.59822645
74GRK60.58272655
75* CSNK2A10.58161295
76MST1R0.57628891
77DMPK0.57499804
78STK38L0.57393900
79CSF1R0.55787197
80ALK0.55546885
81RPS6KA50.55285794
82ERBB40.54992566
83CDK11A0.54451615
84IRAK40.54014417
85CDK150.53528490
86CSNK1E0.53415830
87CDK180.52967835
88NEK90.51612071
89KIT0.50847838
90YES10.50022256
91ZAP700.49101112
92CDK90.48646850
93EIF2AK20.48526055
94TYK20.47389469
95CDK140.46626673
96IRAK30.43699260
97BCR0.42976265
98TRIM280.42030231
99FGFR30.41925822
100PRKDC0.41862414
101CHUK0.40970548
102CDK30.37597105
103STK240.36329002
104MAPK140.35559750
105MAP3K60.34476314
106KDR0.33390947
107LYN0.33274138
108CSNK1D0.33004792
109ERBB30.32981264
110TXK0.32660262
111MARK30.32596058
112LCK0.31873160
113AKT10.31116567
114SYK0.29645110
115MTOR0.29617722
116MAPK110.29479213
117LATS10.28995260
118AKT20.28772792
119PAK10.26740855
120FGFR10.26712861
121PDGFRA0.24984394
122NME10.24244417
123MET0.24104937
124NUAK10.23877750
125DYRK1B0.23843974
126ICK0.23522274
127TRPM70.23409024
128DAPK10.18760758
129BMX0.18742328
130KSR10.18102190
131GSK3B0.17954183
132PAK20.16097023

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.61748720
2Mismatch repair_Homo sapiens_hsa034304.59059271
3Homologous recombination_Homo sapiens_hsa034403.41500072
4Spliceosome_Homo sapiens_hsa030403.25548429
5Base excision repair_Homo sapiens_hsa034103.20288255
6Cell cycle_Homo sapiens_hsa041103.16967441
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.83591479
8Nucleotide excision repair_Homo sapiens_hsa034202.82017474
9Ribosome_Homo sapiens_hsa030102.80924324
10RNA transport_Homo sapiens_hsa030132.73194446
11Fanconi anemia pathway_Homo sapiens_hsa034602.56264206
12One carbon pool by folate_Homo sapiens_hsa006702.48095516
13Non-homologous end-joining_Homo sapiens_hsa034502.33452375
14Pyrimidine metabolism_Homo sapiens_hsa002401.96734881
15RNA polymerase_Homo sapiens_hsa030201.92594369
16RNA degradation_Homo sapiens_hsa030181.86504862
17mRNA surveillance pathway_Homo sapiens_hsa030151.85377209
18p53 signaling pathway_Homo sapiens_hsa041151.81700080
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.70315320
20Systemic lupus erythematosus_Homo sapiens_hsa053221.65588284
21Proteasome_Homo sapiens_hsa030501.58641161
22Basal transcription factors_Homo sapiens_hsa030221.47664452
23Herpes simplex infection_Homo sapiens_hsa051681.39836096
24Antigen processing and presentation_Homo sapiens_hsa046121.28256588
25Viral carcinogenesis_Homo sapiens_hsa052031.22299113
26Protein export_Homo sapiens_hsa030601.20070393
27Primary immunodeficiency_Homo sapiens_hsa053401.14205255
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.12493216
29Epstein-Barr virus infection_Homo sapiens_hsa051691.11544995
30Pyruvate metabolism_Homo sapiens_hsa006201.06743751
31Small cell lung cancer_Homo sapiens_hsa052221.05710751
32HTLV-I infection_Homo sapiens_hsa051661.03482207
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.01544054
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.01051891
35MicroRNAs in cancer_Homo sapiens_hsa052061.00994421
36Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96229106
37Oocyte meiosis_Homo sapiens_hsa041140.93414284
38Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.93258032
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92229191
40Purine metabolism_Homo sapiens_hsa002300.88638693
41NF-kappa B signaling pathway_Homo sapiens_hsa040640.84544819
42Measles_Homo sapiens_hsa051620.84057280
43Hepatitis B_Homo sapiens_hsa051610.81930564
44Carbon metabolism_Homo sapiens_hsa012000.81459559
45Thyroid cancer_Homo sapiens_hsa052160.78037572
46Chronic myeloid leukemia_Homo sapiens_hsa052200.76174990
47Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72272773
48Hematopoietic cell lineage_Homo sapiens_hsa046400.71916524
49Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71459107
50Huntingtons disease_Homo sapiens_hsa050160.71175688
512-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.69849985
52Legionellosis_Homo sapiens_hsa051340.69480699
53Apoptosis_Homo sapiens_hsa042100.68684396
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66315486
55Colorectal cancer_Homo sapiens_hsa052100.66015186
56Intestinal immune network for IgA production_Homo sapiens_hsa046720.62013283
57Parkinsons disease_Homo sapiens_hsa050120.61983512
58Leishmaniasis_Homo sapiens_hsa051400.61963722
59Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61698567
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58685113
61Alcoholism_Homo sapiens_hsa050340.57692651
62Viral myocarditis_Homo sapiens_hsa054160.57396404
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56952799
64Influenza A_Homo sapiens_hsa051640.55258536
65TGF-beta signaling pathway_Homo sapiens_hsa043500.54166901
66Pancreatic cancer_Homo sapiens_hsa052120.53823912
67Shigellosis_Homo sapiens_hsa051310.53757719
68Notch signaling pathway_Homo sapiens_hsa043300.53455676
69Selenocompound metabolism_Homo sapiens_hsa004500.52847026
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.51823780
71B cell receptor signaling pathway_Homo sapiens_hsa046620.51383393
72RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.51113971
73Wnt signaling pathway_Homo sapiens_hsa043100.50173394
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.50067380
75Pentose phosphate pathway_Homo sapiens_hsa000300.49536279
76Prostate cancer_Homo sapiens_hsa052150.48286535
77Non-small cell lung cancer_Homo sapiens_hsa052230.47098181
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46496607
79Basal cell carcinoma_Homo sapiens_hsa052170.45036797
80Lysine degradation_Homo sapiens_hsa003100.44852693
81Steroid biosynthesis_Homo sapiens_hsa001000.43218529
82Pathways in cancer_Homo sapiens_hsa052000.43181507
83Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42684587
84Propanoate metabolism_Homo sapiens_hsa006400.42679480
85Vitamin B6 metabolism_Homo sapiens_hsa007500.42272859
86Bladder cancer_Homo sapiens_hsa052190.41336712
87Oxidative phosphorylation_Homo sapiens_hsa001900.40673749
88Jak-STAT signaling pathway_Homo sapiens_hsa046300.40530405
89Adherens junction_Homo sapiens_hsa045200.40066281
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.39132337
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.38449816
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.38368246
93Acute myeloid leukemia_Homo sapiens_hsa052210.37795861
94Toxoplasmosis_Homo sapiens_hsa051450.35954700
95Hippo signaling pathway_Homo sapiens_hsa043900.35822806
96Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.35520794
97T cell receptor signaling pathway_Homo sapiens_hsa046600.35515066
98Melanoma_Homo sapiens_hsa052180.35357627
99Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34089641
100Hedgehog signaling pathway_Homo sapiens_hsa043400.33608084
101Drug metabolism - other enzymes_Homo sapiens_hsa009830.32958252
102Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32117892
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.31167626
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.31100789
105HIF-1 signaling pathway_Homo sapiens_hsa040660.31070800
106Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30440278
107Toll-like receptor signaling pathway_Homo sapiens_hsa046200.29967121
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.29858437
109Allograft rejection_Homo sapiens_hsa053300.29440947
110N-Glycan biosynthesis_Homo sapiens_hsa005100.28706294
111Fatty acid elongation_Homo sapiens_hsa000620.26801467
112Osteoclast differentiation_Homo sapiens_hsa043800.25856100
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.25650664
114Biosynthesis of amino acids_Homo sapiens_hsa012300.24665374
115Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24632456
116Endometrial cancer_Homo sapiens_hsa052130.24510893
117Asthma_Homo sapiens_hsa053100.24380241
118Renal cell carcinoma_Homo sapiens_hsa052110.24272486
119Platelet activation_Homo sapiens_hsa046110.23835447
120Alzheimers disease_Homo sapiens_hsa050100.23593874
121Graft-versus-host disease_Homo sapiens_hsa053320.23381680
122TNF signaling pathway_Homo sapiens_hsa046680.23085581
123Proteoglycans in cancer_Homo sapiens_hsa052050.23078112
124FoxO signaling pathway_Homo sapiens_hsa040680.22967625
125Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.22125249
126Glutathione metabolism_Homo sapiens_hsa004800.22059998
127Folate biosynthesis_Homo sapiens_hsa007900.19584440
128mTOR signaling pathway_Homo sapiens_hsa041500.19304155
129Metabolic pathways_Homo sapiens_hsa011000.18189161
130Glioma_Homo sapiens_hsa052140.11599385
131Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.11073037
132Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.10204840
133Thyroid hormone signaling pathway_Homo sapiens_hsa049190.09563743
134Tight junction_Homo sapiens_hsa045300.09485503
135Galactose metabolism_Homo sapiens_hsa000520.07716259

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