DENND6A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.31447202
2phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.96514081
3definitive hemopoiesis (GO:0060216)3.89068808
4cytoplasmic mRNA processing body assembly (GO:0033962)3.76098830
5mitotic sister chromatid cohesion (GO:0007064)3.75288840
6positive T cell selection (GO:0043368)3.66998537
7alpha-beta T cell differentiation (GO:0046632)3.65319406
8cellular extravasation (GO:0045123)3.65015256
9negative regulation of neurotransmitter secretion (GO:0046929)3.52553881
10protein K11-linked deubiquitination (GO:0035871)3.48028702
11CD4-positive, alpha-beta T cell differentiation (GO:0043367)3.41826415
12positive regulation of granulocyte differentiation (GO:0030854)3.41486982
13protein K48-linked deubiquitination (GO:0071108)3.41207142
14CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.39426803
15T-helper cell differentiation (GO:0042093)3.39426803
16regulation of pigment cell differentiation (GO:0050932)3.38852759
17positive regulation of developmental pigmentation (GO:0048087)3.37422334
18alpha-beta T cell activation (GO:0046631)3.34615655
19cellular response to ethanol (GO:0071361)3.33107515
20negative T cell selection (GO:0043383)3.32521513
21nuclear pore complex assembly (GO:0051292)3.28059659
22negative thymic T cell selection (GO:0045060)3.27125139
23establishment of protein localization to Golgi (GO:0072600)3.26656968
24activated T cell proliferation (GO:0050798)3.26139266
25negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.23898085
26negative regulation of cell killing (GO:0031342)3.23898085
27regulation of B cell receptor signaling pathway (GO:0050855)3.16983211
28tolerance induction (GO:0002507)3.16916345
29alpha-beta T cell differentiation involved in immune response (GO:0002293)3.08368112
30alpha-beta T cell activation involved in immune response (GO:0002287)3.08368112
31T cell differentiation involved in immune response (GO:0002292)3.08368112
32protein targeting to Golgi (GO:0000042)3.07767824
33histone H3-K36 demethylation (GO:0070544)3.07105634
34necroptotic process (GO:0070266)3.03332190
35nuclear pore organization (GO:0006999)3.02357761
36CD4-positive, alpha-beta T cell activation (GO:0035710)2.99903590
37necrotic cell death (GO:0070265)2.99521237
38retrograde transport, vesicle recycling within Golgi (GO:0000301)2.98722917
39hepatocyte apoptotic process (GO:0097284)2.98506327
40negative regulation of DNA-dependent DNA replication (GO:2000104)2.97769164
41protein K63-linked deubiquitination (GO:0070536)2.97674383
42regulation of DNA endoreduplication (GO:0032875)2.94383656
43neutrophil mediated immunity (GO:0002446)2.94300974
44negative regulation of neurotransmitter transport (GO:0051589)2.91760932
45Golgi to endosome transport (GO:0006895)2.90211629
46T cell selection (GO:0045058)2.87437237
47embryonic hemopoiesis (GO:0035162)2.87316279
48response to muramyl dipeptide (GO:0032495)2.83665135
49embryonic camera-type eye morphogenesis (GO:0048596)2.82506159
50negative regulation of T cell mediated immunity (GO:0002710)2.81352642
51kinetochore organization (GO:0051383)2.80723859
52T cell differentiation (GO:0030217)2.79841684
53positive regulation of DNA-dependent DNA replication (GO:2000105)2.78359622
54early endosome to late endosome transport (GO:0045022)2.78090442
55regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.76927606
56regulation of chromatin silencing (GO:0031935)2.75446860
57neural tube formation (GO:0001841)2.75424667
58polyol transport (GO:0015791)2.75084466
59sister chromatid cohesion (GO:0007062)2.74819289
60negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.74707411
61negative regulation of translation, ncRNA-mediated (GO:0040033)2.74707411
62regulation of translation, ncRNA-mediated (GO:0045974)2.74707411
63interkinetic nuclear migration (GO:0022027)2.71693399
64regulation of protein polyubiquitination (GO:1902914)2.71117616
65response to interleukin-15 (GO:0070672)2.70912470
66negative regulation of histone methylation (GO:0031061)2.70529415
67pericardium development (GO:0060039)2.69933019
68positive regulation of gamma-delta T cell activation (GO:0046645)2.69051244
69negative regulation of interleukin-12 production (GO:0032695)2.66691677
70regulation of gamma-delta T cell differentiation (GO:0045586)2.66659632
71negative regulation of granulocyte differentiation (GO:0030853)2.65606214
72regulation of interferon-beta biosynthetic process (GO:0045357)2.64200237
73lymph vessel development (GO:0001945)2.63929321
74peptidyl-lysine trimethylation (GO:0018023)2.62488887
75histone H3-K4 trimethylation (GO:0080182)2.61746689
76programmed necrotic cell death (GO:0097300)2.59905895
77histone lysine demethylation (GO:0070076)2.59432828
783-UTR-mediated mRNA stabilization (GO:0070935)2.58757279
79lipid translocation (GO:0034204)2.58747376
80phospholipid translocation (GO:0045332)2.58747376
81positive thymic T cell selection (GO:0045059)2.58301679
82regulation of histone H3-K9 methylation (GO:0051570)2.56897618
83dosage compensation (GO:0007549)2.56725558
84microglial cell activation (GO:0001774)2.56542154
85myeloid leukocyte mediated immunity (GO:0002444)2.56497344
86regulation of Golgi to plasma membrane protein transport (GO:0042996)2.55965686
87monoubiquitinated protein deubiquitination (GO:0035520)2.55254560
88type B pancreatic cell development (GO:0003323)2.55165929
89histone demethylation (GO:0016577)2.54058566
90paraxial mesoderm development (GO:0048339)2.53615685
91kinetochore assembly (GO:0051382)2.53342299
92negative regulation of cAMP-mediated signaling (GO:0043951)2.53103540
93immunoglobulin mediated immune response (GO:0016064)2.51967748
94meiotic chromosome segregation (GO:0045132)2.51808400
95T cell migration (GO:0072678)2.51680326
96histone mRNA catabolic process (GO:0071044)2.48418585
97regulation of helicase activity (GO:0051095)2.47751485
98leukocyte aggregation (GO:0070486)2.47668901
99interferon-gamma production (GO:0032609)2.47314350
100mesenchymal cell differentiation involved in kidney development (GO:0072161)2.46184352
101mesenchymal cell differentiation involved in renal system development (GO:2001012)2.46184352
102negative regulation of stress fiber assembly (GO:0051497)2.46095984
103regulation of granulocyte differentiation (GO:0030852)2.44890334
104pore complex assembly (GO:0046931)2.44864266
105negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.44345414
106negative regulation of mast cell activation (GO:0033004)2.44169732
107positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.44151046
108nucleus localization (GO:0051647)2.43395580
109positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.43248314
110radial glial cell differentiation (GO:0060019)2.42703820
111negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.41536235
112regulation of fibroblast apoptotic process (GO:2000269)2.40283980
113regulation of interleukin-12 biosynthetic process (GO:0045075)2.40247736
114snRNA transcription (GO:0009301)2.39585717
115regulation of telomere maintenance via telomerase (GO:0032210)2.38466213
116negative regulation of cell cycle G2/M phase transition (GO:1902750)2.38386019
117regulation of gene silencing (GO:0060968)2.37549583
118regulation of histone H3-K27 methylation (GO:0061085)2.36328408
119exocrine pancreas development (GO:0031017)2.34390546
120DNA damage induced protein phosphorylation (GO:0006975)2.33912071
121T cell activation involved in immune response (GO:0002286)2.33703890
122mesenchymal cell differentiation (GO:0048762)2.33581488
123cellular response to interleukin-15 (GO:0071350)2.33564050
124histone-serine phosphorylation (GO:0035404)2.32819037
125histone H3-K9 demethylation (GO:0033169)2.32775418
126glomerulus development (GO:0032835)2.32192670
127regulation of nuclear cell cycle DNA replication (GO:0033262)2.30924491
128regulation of sister chromatid cohesion (GO:0007063)2.30850570
129positive regulation by host of viral transcription (GO:0043923)2.30557937
130cAMP catabolic process (GO:0006198)2.30350328
131regulation of establishment of cell polarity (GO:2000114)2.30190357
132gland morphogenesis (GO:0022612)2.29726918
133growth hormone receptor signaling pathway (GO:0060396)2.28849601
134histone H3-K9 methylation (GO:0051567)2.28739568
135fibroblast migration (GO:0010761)2.28562725
136DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.28009985
137pre-miRNA processing (GO:0031054)2.23869681
138negative regulation of glycogen biosynthetic process (GO:0045719)2.22568104
139genitalia morphogenesis (GO:0035112)2.22327352
140phagocytosis, engulfment (GO:0006911)2.22271065
141negative regulation of protein autophosphorylation (GO:0031953)2.22094660
142female gonad development (GO:0008585)2.22042169
143positive regulation of SMAD protein import into nucleus (GO:0060391)2.21512048
144regulation of transforming growth factor beta2 production (GO:0032909)2.21059393
145modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.21026680
146positive regulation by organism of defense response of other organism involved in symbiotic interact2.21026680
147modulation by symbiont of host immune response (GO:0052553)2.21026680
148positive regulation by symbiont of host defense response (GO:0052509)2.21026680
149modulation by symbiont of host defense response (GO:0052031)2.21026680
150modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.21026680
151positive regulation of interferon-alpha production (GO:0032727)2.18927597
152positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.18009979
153positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.18009979
154positive regulation of mitotic sister chromatid separation (GO:1901970)2.18009979
155I-kappaB phosphorylation (GO:0007252)2.17953528
156positive regulation of interleukin-1 beta secretion (GO:0050718)2.17140993
157positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.16947884
158cellular anion homeostasis (GO:0030002)2.16229805
159myoblast migration (GO:0051451)2.16015453
160positive regulation of gene expression, epigenetic (GO:0045815)2.15386534
161protein dealkylation (GO:0008214)2.15164719
162protein demethylation (GO:0006482)2.15164719
163histone H3-K9 modification (GO:0061647)2.15108605
164regulation of steroid hormone biosynthetic process (GO:0090030)2.14665532
165regulation of establishment or maintenance of cell polarity (GO:0032878)2.14407728
166bone remodeling (GO:0046849)2.14120143
167positive regulation of interleukin-1 secretion (GO:0050716)2.13779998
168negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.13418188
169oocyte maturation (GO:0001556)2.13033313
170regulation of DNA-dependent DNA replication (GO:0090329)2.12317808
171embryonic retina morphogenesis in camera-type eye (GO:0060059)2.11629059
172metaphase plate congression (GO:0051310)2.11423375
173corticosteroid receptor signaling pathway (GO:0031958)2.11232258
174histone H2A monoubiquitination (GO:0035518)2.10847906
175glandular epithelial cell development (GO:0002068)2.10594227
176regulation of gamma-delta T cell activation (GO:0046643)2.10482195
177B cell mediated immunity (GO:0019724)2.08840109
178negative regulation of B cell proliferation (GO:0030889)2.07999041

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.87633615
2SALL1_21062744_ChIP-ChIP_HESCs_Human3.43406650
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.41551705
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.37339317
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.36993662
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.08326685
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.98983304
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.96309904
9CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.69571148
10SCL_19346495_ChIP-Seq_HPC-7_Human2.43344488
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.33035611
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.29462249
13IRF8_21731497_ChIP-ChIP_J774_Mouse2.29088028
14IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.19691037
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.15976928
16GBX2_23144817_ChIP-Seq_PC3_Human2.08881468
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.04813835
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.92583592
19EGR1_19374776_ChIP-ChIP_THP-1_Human1.90821228
20KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.87725593
21ER_23166858_ChIP-Seq_MCF-7_Human1.84267890
22TAF15_26573619_Chip-Seq_HEK293_Human1.82379736
23HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.81587218
24SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.80070889
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.76696675
26ZNF274_21170338_ChIP-Seq_K562_Hela1.76100155
27IRF8_27001747_Chip-Seq_BMDM_Mouse1.75360707
28GATA2_21666600_ChIP-Seq_HMVEC_Human1.73456194
29RUNX_20019798_ChIP-Seq_JUKART_Human1.73392191
30FLI1_27457419_Chip-Seq_LIVER_Mouse1.72831540
31STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.67739312
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.67189655
33RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64920720
34PCGF2_27294783_Chip-Seq_NPCs_Mouse1.64583167
35POU3F2_20337985_ChIP-ChIP_501MEL_Human1.63777604
36VDR_22108803_ChIP-Seq_LS180_Human1.63467277
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.59495228
38EGR1_23403033_ChIP-Seq_LIVER_Mouse1.59033599
39Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.54718111
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.54230135
41P300_19829295_ChIP-Seq_ESCs_Human1.54120182
42FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.49392814
43MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.48499257
44NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.47930742
45NFE2_27457419_Chip-Seq_LIVER_Mouse1.47666664
46AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.47142016
47NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.45065870
48FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.44662573
49SUZ12_27294783_Chip-Seq_NPCs_Mouse1.43478692
50STAT3_23295773_ChIP-Seq_U87_Human1.39995709
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37159387
52AR_21909140_ChIP-Seq_LNCAP_Human1.36077824
53RBPJ_22232070_ChIP-Seq_NCS_Mouse1.35599928
54GATA3_27048872_Chip-Seq_THYMUS_Human1.34851676
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.34187020
56EWS_26573619_Chip-Seq_HEK293_Human1.33958951
57CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.33670324
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.33159714
59ZNF217_24962896_ChIP-Seq_MCF-7_Human1.32510297
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31599419
61STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.31527919
62SMAD4_21799915_ChIP-Seq_A2780_Human1.30566984
63PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.30336951
64AR_21572438_ChIP-Seq_LNCaP_Human1.29771866
65FLI1_21867929_ChIP-Seq_TH2_Mouse1.29468317
66GATA1_22025678_ChIP-Seq_K562_Human1.29177698
67FUS_26573619_Chip-Seq_HEK293_Human1.27738099
68UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27711902
69TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26488975
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26488975
71IGF1R_20145208_ChIP-Seq_DFB_Human1.25965899
72GATA3_26560356_Chip-Seq_TH2_Human1.24256045
73SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24151438
74SALL4_18804426_ChIP-ChIP_XEN_Mouse1.22084302
75FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.21868680
76SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20293424
77TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20271121
78FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19371295
79NANOG_18555785_Chip-Seq_ESCs_Mouse1.18928698
80FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.17438623
81MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16647297
82CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16299924
83IRF1_19129219_ChIP-ChIP_H3396_Human1.14224227
84EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13714427
85POU5F1_16153702_ChIP-ChIP_HESCs_Human1.13242320
86TCF4_23295773_ChIP-Seq_U87_Human1.12438530
87GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.11295934
88PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10713255
89IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10648214
90CBP_20019798_ChIP-Seq_JUKART_Human1.10648214
91STAT3_18555785_Chip-Seq_ESCs_Mouse1.09490864
92PRDM14_20953172_ChIP-Seq_ESCs_Human1.09463603
93E2F1_18555785_Chip-Seq_ESCs_Mouse1.08841698
94SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08433045
95PKCTHETA_26484144_Chip-Seq_BREAST_Human1.08415810
96OCT4_18555785_Chip-Seq_ESCs_Mouse1.08170819
97NOTCH1_21737748_ChIP-Seq_TLL_Human1.07535315
98PU_27001747_Chip-Seq_BMDM_Mouse1.06863227
99BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.04385629
100PIAS1_25552417_ChIP-Seq_VCAP_Human1.04141144
101TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03597760
102P53_22387025_ChIP-Seq_ESCs_Mouse1.03342968
103P300_18555785_Chip-Seq_ESCs_Mouse1.02362456
104GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01974978
105CMYC_18555785_Chip-Seq_ESCs_Mouse1.01915322
106TCF4_18268006_ChIP-ChIP_LS174T_Human1.01315758
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.01280595
108CTBP1_25329375_ChIP-Seq_LNCAP_Human1.01152154
109MYB_21317192_ChIP-Seq_ERMYB_Mouse1.01019605
110CDX2_22108803_ChIP-Seq_LS180_Human1.00796710
111ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00096815
112VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00087131
113NMYC_18555785_Chip-Seq_ESCs_Mouse0.99809174
114SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.99252480
115ZFX_18555785_Chip-Seq_ESCs_Mouse0.99178403
116TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98990978
117SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.98867118
118SMAD3_21741376_ChIP-Seq_EPCs_Human0.98792665
119MYB_26560356_Chip-Seq_TH2_Human0.98466105
120CRX_20693478_ChIP-Seq_RETINA_Mouse0.97848294
121RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.97787986
122SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.96904383
123CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96887434
124NRF2_20460467_ChIP-Seq_MEFs_Mouse0.96163919
125NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.96163919
126MYB_26560356_Chip-Seq_TH1_Human0.95679397
127TP53_16413492_ChIP-PET_HCT116_Human0.95205027
128VDR_24787735_ChIP-Seq_THP-1_Human0.94416056
129OCT4_21477851_ChIP-Seq_ESCs_Mouse0.94226363
130FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.93700166
131MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.93357398
132SOX2_18555785_Chip-Seq_ESCs_Mouse0.92206527
133EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.91300003
134FOXA1_25552417_ChIP-Seq_VCAP_Human0.89294215
135BRD4_25478319_ChIP-Seq_HGPS_Human0.89275647
136ESRRB_18555785_Chip-Seq_ESCs_Mouse0.88796103
137TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.88429004
138RUNX1_27457419_Chip-Seq_LIVER_Mouse0.87556351

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003724_increased_susceptibility_to2.98877878
2MP0002009_preneoplasia2.47013396
3MP0008961_abnormal_basal_metabolism2.45056324
4MP0000569_abnormal_digit_pigmentation2.39901197
5MP0006292_abnormal_olfactory_placode2.35166565
6MP0004484_altered_response_of2.18096411
7MP0001879_abnormal_lymphatic_vessel2.07891591
8MP0004264_abnormal_extraembryonic_tissu2.00904077
9MP0010368_abnormal_lymphatic_system1.98428594
10MP0002837_dystrophic_cardiac_calcinosis1.96411298
11MP0004381_abnormal_hair_follicle1.94600366
12MP0002396_abnormal_hematopoietic_system1.91857971
13MP0005248_abnormal_Harderian_gland1.89528630
14MP0002166_altered_tumor_susceptibility1.81811772
15MP0004808_abnormal_hematopoietic_stem1.81667042
16MP0003656_abnormal_erythrocyte_physiolo1.77462499
17MP0003646_muscle_fatigue1.75074260
18MP0001835_abnormal_antigen_presentation1.72201467
19MP0003890_abnormal_embryonic-extraembry1.70912793
20MP0002877_abnormal_melanocyte_morpholog1.68892854
21MP0004084_abnormal_cardiac_muscle1.68588066
22MP0003787_abnormal_imprinting1.68188894
23MP0003221_abnormal_cardiomyocyte_apopto1.66220147
24MP0010234_abnormal_vibrissa_follicle1.64441438
25MP0002138_abnormal_hepatobiliary_system1.63117194
26MP0002006_tumorigenesis1.62777570
27MP0000566_synostosis1.62270416
28MP0008057_abnormal_DNA_replication1.60294433
29MP0002405_respiratory_system_inflammati1.60153927
30MP0010094_abnormal_chromosome_stability1.57888959
31MP0003436_decreased_susceptibility_to1.55057172
32MP0003121_genomic_imprinting1.53678663
33MP0004130_abnormal_muscle_cell1.52591731
34MP0003943_abnormal_hepatobiliary_system1.50287348
35MP0002928_abnormal_bile_duct1.43498335
36MP0003300_gastrointestinal_ulcer1.42750325
37MP0003252_abnormal_bile_duct1.42006350
38MP0000490_abnormal_crypts_of1.41614868
39MP0003303_peritoneal_inflammation1.39339678
40MP0010352_gastrointestinal_tract_polyps1.38382671
41MP0003077_abnormal_cell_cycle1.37614090
42MP0002277_abnormal_respiratory_mucosa1.37126184
43MP0006054_spinal_hemorrhage1.35789646
44MP0001293_anophthalmia1.35351343
45MP0000613_abnormal_salivary_gland1.33493690
46MP0003937_abnormal_limbs/digits/tail_de1.33274498
47MP0000767_abnormal_smooth_muscle1.30930025
48MP0005408_hypopigmentation1.28666663
49MP0005174_abnormal_tail_pigmentation1.27653418
50MP0003868_abnormal_feces_composition1.27575549
51MP0001800_abnormal_humoral_immune1.23827248
52MP0000685_abnormal_immune_system1.22640706
53MP0010678_abnormal_skin_adnexa1.22267040
54MP0003567_abnormal_fetal_cardiomyocyte1.21285568
55MP0001851_eye_inflammation1.20229194
56MP0000516_abnormal_urinary_system1.19895542
57MP0005367_renal/urinary_system_phenotyp1.19895542
58MP0000383_abnormal_hair_follicle1.19102666
59MP0005220_abnormal_exocrine_pancreas1.17755064
60MP0005076_abnormal_cell_differentiation1.16455783
61MP0002095_abnormal_skin_pigmentation1.16256110
62MP0002452_abnormal_antigen_presenting1.15851422
63MP0005310_abnormal_salivary_gland1.15317001
64MP0004883_abnormal_blood_vessel1.14459658
65MP0003195_calcinosis1.10460115
66MP0005000_abnormal_immune_tolerance1.10267317
67MP0002234_abnormal_pharynx_morphology1.10263458
68MP0002098_abnormal_vibrissa_morphology1.09777245
69MP0005671_abnormal_response_to1.09048648
70MP0009115_abnormal_fat_cell1.06818750
71MP0002398_abnormal_bone_marrow1.05594899
72MP0010307_abnormal_tumor_latency1.05169783
73MP0000465_gastrointestinal_hemorrhage1.03596364
74MP0003693_abnormal_embryo_hatching1.03533347
75MP0000427_abnormal_hair_cycle1.02854273
76MP0002132_abnormal_respiratory_system1.02194162
77MP0010155_abnormal_intestine_physiology1.00574909
78MP0001188_hyperpigmentation1.00291195
79MP0001119_abnormal_female_reproductive0.98943779
80MP0008004_abnormal_stomach_pH0.97859505
81MP0003828_pulmonary_edema0.97105097
82MP0000537_abnormal_urethra_morphology0.95208979
83MP0003111_abnormal_nucleus_morphology0.94665814
84MP0001919_abnormal_reproductive_system0.94266963
85MP0008995_early_reproductive_senescence0.94209277
86MP0000432_abnormal_head_morphology0.94080840
87MP0002420_abnormal_adaptive_immunity0.93451822
88MP0008058_abnormal_DNA_repair0.92392262
89MP0002697_abnormal_eye_size0.92163219
90MP0001819_abnormal_immune_cell0.92144960
91MP0000371_diluted_coat_color0.91835865
92MP0008007_abnormal_cellular_replicative0.90952839
93MP0000716_abnormal_immune_system0.90892286
94MP0002249_abnormal_larynx_morphology0.90801017
95MP0005503_abnormal_tendon_morphology0.90800519
96MP0000689_abnormal_spleen_morphology0.90341523
97MP0003763_abnormal_thymus_physiology0.90157633
98MP0002693_abnormal_pancreas_physiology0.89365409
99MP0002102_abnormal_ear_morphology0.89066402
100MP0005025_abnormal_response_to0.88642985
101MP0002086_abnormal_extraembryonic_tissu0.88463152
102MP0009697_abnormal_copulation0.88364863
103MP0002419_abnormal_innate_immunity0.86260232
104MP0002092_abnormal_eye_morphology0.85992466
105MP0003935_abnormal_craniofacial_develop0.85979491
106MP0003866_abnormal_defecation0.85164252
107MP0008260_abnormal_autophagy0.84136260
108MP0002177_abnormal_outer_ear0.84029744
109MP0001845_abnormal_inflammatory_respons0.83962509
110MP0001790_abnormal_immune_system0.83492852
111MP0005387_immune_system_phenotype0.83492852
112MP0005409_darkened_coat_color0.83003146
113MP0000015_abnormal_ear_pigmentation0.82965642
114MP0000703_abnormal_thymus_morphology0.82825515
115MP0001286_abnormal_eye_development0.82618017
116MP0009785_altered_susceptibility_to0.81974311
117MP0005380_embryogenesis_phenotype0.81933471
118MP0001672_abnormal_embryogenesis/_devel0.81933471
119MP0002168_other_aberrant_phenotype0.81722534
120MP0002722_abnormal_immune_system0.81276202
121MP0003315_abnormal_perineum_morphology0.81260956
122MP0002723_abnormal_immune_serum0.81107658
123MP0005464_abnormal_platelet_physiology0.80223796
124MP0005666_abnormal_adipose_tissue0.79792646
125MP0002938_white_spotting0.79514125
126MP0002933_joint_inflammation0.79049652
127MP0001915_intracranial_hemorrhage0.78152477
128MP0002084_abnormal_developmental_patter0.77868731
129MP0002127_abnormal_cardiovascular_syste0.77541260
130MP0005075_abnormal_melanosome_morpholog0.77276986
131MP0002429_abnormal_blood_cell0.77224614
132MP0000470_abnormal_stomach_morphology0.76203643
133MP0004185_abnormal_adipocyte_glucose0.74010916
134MP0009764_decreased_sensitivity_to0.72471143
135MP0004036_abnormal_muscle_relaxation0.71795588
136MP0005647_abnormal_sex_gland0.71533314
137MP0005389_reproductive_system_phenotype0.71369068
138MP0001784_abnormal_fluid_regulation0.70377057
139MP0001873_stomach_inflammation0.69136278
140MP0002163_abnormal_gland_morphology0.68959447
141MP0003045_fibrosis0.67133014
142MP0004215_abnormal_myocardial_fiber0.64008809
143MP0005397_hematopoietic_system_phenotyp0.63602258
144MP0001545_abnormal_hematopoietic_system0.63602258
145MP0000631_abnormal_neuroendocrine_gland0.62152670
146MP0005253_abnormal_eye_physiology0.61548148
147MP0002088_abnormal_embryonic_growth/wei0.60552096
148MP0006082_CNS_inflammation0.59688315
149MP0002971_abnormal_brown_adipose0.59282657
150MP0005266_abnormal_metabolism0.58313141

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.82570480
2Stomach cancer (HP:0012126)3.81590824
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.71632893
4Abnormality of the fingertips (HP:0001211)3.62858859
5T lymphocytopenia (HP:0005403)3.55653690
6Abnormality of T cell number (HP:0011839)3.51439647
7Absent rod-and cone-mediated responses on ERG (HP:0007688)3.22852438
8Volvulus (HP:0002580)3.21978753
9Eczematoid dermatitis (HP:0000976)3.12917115
10Hematochezia (HP:0002573)3.02238336
11Subaortic stenosis (HP:0001682)2.82017287
12Abnormality of the left ventricular outflow tract (HP:0011103)2.82017287
13Prostate neoplasm (HP:0100787)2.79197744
14Curly hair (HP:0002212)2.76875735
15Acute myeloid leukemia (HP:0004808)2.62411700
16Lip pit (HP:0100267)2.53381062
17Ectopic kidney (HP:0000086)2.47923089
18Thyroiditis (HP:0100646)2.44706373
19Subacute progressive viral hepatitis (HP:0006572)2.41464857
20Hypoplasia of the thymus (HP:0000778)2.40625493
21Stomatitis (HP:0010280)2.40035186
22Eosinophilia (HP:0001880)2.39440850
23Long eyelashes (HP:0000527)2.36791738
24Abnormality of eosinophils (HP:0001879)2.36741662
25Chronic diarrhea (HP:0002028)2.35652299
26Large earlobe (HP:0009748)2.34786708
27Myocardial infarction (HP:0001658)2.34423543
28Agammaglobulinemia (HP:0004432)2.33202633
29Thyroid carcinoma (HP:0002890)2.30990112
30Abnormality of the nasal septum (HP:0000419)2.29207188
31Shawl scrotum (HP:0000049)2.26649329
32Recurrent viral infections (HP:0004429)2.25225872
33Abnormal rod and cone electroretinograms (HP:0008323)2.25005289
34Widely spaced teeth (HP:0000687)2.24320727
35Truncal obesity (HP:0001956)2.23941162
36Papilledema (HP:0001085)2.21386614
37Absent frontal sinuses (HP:0002688)2.18203853
38Pancreatic cysts (HP:0001737)2.15006013
39Portal hypertension (HP:0001409)2.14755145
40Abnormality of the hepatic vasculature (HP:0006707)2.13963620
41Hypoplastic labia majora (HP:0000059)2.12633349
42Hypoplastic iliac wings (HP:0002866)2.12584210
43Abnormality of T cells (HP:0002843)2.11693970
44Abnormality of the renal collecting system (HP:0004742)2.11169172
45Fair hair (HP:0002286)2.10857574
46Tubulointerstitial nephritis (HP:0001970)2.10595467
47Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.10259719
48Short 4th metacarpal (HP:0010044)2.10259719
49Autoimmune hemolytic anemia (HP:0001890)2.08971267
50Cerebellar dysplasia (HP:0007033)2.07964258
51Abnormality of chromosome stability (HP:0003220)2.07685688
52Neoplasm of the adrenal cortex (HP:0100641)2.07528665
53Abnormality of B cell number (HP:0010975)2.04223143
54Cone-rod dystrophy (HP:0000548)2.03263293
55Osteomalacia (HP:0002749)2.03042732
56Clubbing of toes (HP:0100760)2.02948659
57Midline defect of the nose (HP:0004122)2.02822943
58Hyperventilation (HP:0002883)2.02737133
59Abnormal biliary tract morphology (HP:0012440)2.02255124
60Viral hepatitis (HP:0006562)2.01731049
61Encephalitis (HP:0002383)2.01690381
62Attenuation of retinal blood vessels (HP:0007843)2.01267164
63Spontaneous hematomas (HP:0007420)1.99805066
64Leukocytosis (HP:0001974)1.99329098
65Severe combined immunodeficiency (HP:0004430)1.98897090
66Supernumerary ribs (HP:0005815)1.97994381
67Pustule (HP:0200039)1.97755307
68Abnormality of the parietal bone (HP:0002696)1.97655623
69Dynein arm defect of respiratory motile cilia (HP:0012255)1.96876042
70Absent/shortened dynein arms (HP:0200106)1.96876042
71Abnormal delayed hypersensitivity skin test (HP:0002963)1.96415266
72Granulocytopenia (HP:0001913)1.96415093
73Inflammation of the large intestine (HP:0002037)1.94110835
74Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.92289910
75Type II lissencephaly (HP:0007260)1.90811996
76Papillary thyroid carcinoma (HP:0002895)1.89646071
77Broad-based gait (HP:0002136)1.88263015
78Abnormality of the labia majora (HP:0012881)1.87994637
79Deep philtrum (HP:0002002)1.87845446
80Keratoconjunctivitis sicca (HP:0001097)1.87649708
81Colitis (HP:0002583)1.87148568
82Transitional cell carcinoma of the bladder (HP:0006740)1.86638756
83Renal cortical cysts (HP:0000803)1.86224283
84Hypochromic microcytic anemia (HP:0004840)1.86151991
85Prolonged bleeding time (HP:0003010)1.86105622
86Spondylolisthesis (HP:0003302)1.85780016
87IgM deficiency (HP:0002850)1.85507107
88Acute lymphatic leukemia (HP:0006721)1.85477379
89Chronic hepatic failure (HP:0100626)1.84567742
90Recurrent fungal infections (HP:0002841)1.83153614
91Panhypogammaglobulinemia (HP:0003139)1.82091221
92Abnormality of the renal cortex (HP:0011035)1.81803462
93White forelock (HP:0002211)1.81499075
94Basal cell carcinoma (HP:0002671)1.79781349
95Excessive salivation (HP:0003781)1.79462603
96Medulloblastoma (HP:0002885)1.79409681
97Cystic hygroma (HP:0000476)1.79202223
98Hypophosphatemic rickets (HP:0004912)1.78593404
99Aplasia/Hypoplasia of the uvula (HP:0010293)1.78032119
100Tented upper lip vermilion (HP:0010804)1.78004691
101Keratoconjunctivitis (HP:0001096)1.77063425
102Meckel diverticulum (HP:0002245)1.76583310
103Recurrent abscess formation (HP:0002722)1.75926704
104Duplicated collecting system (HP:0000081)1.75504400
105Tapered finger (HP:0001182)1.75454025
106Mediastinal lymphadenopathy (HP:0100721)1.74848610
107Retrobulbar optic neuritis (HP:0100654)1.74031258
108Optic neuritis (HP:0100653)1.74031258
109Gastrointestinal carcinoma (HP:0002672)1.73728663
110Malignant gastrointestinal tract tumors (HP:0006749)1.73728663
111Protruding tongue (HP:0010808)1.73533574
112Nephroblastoma (Wilms tumor) (HP:0002667)1.73465130
113Biliary tract neoplasm (HP:0100574)1.73414267
114Thickened calvaria (HP:0002684)1.73226151
115Drooling (HP:0002307)1.73133637
116Sandal gap (HP:0001852)1.72868765
117Recurrent skin infections (HP:0001581)1.72659596
118Patchy hypopigmentation of hair (HP:0011365)1.72130087
119Neoplasm of the oral cavity (HP:0100649)1.72095447
120Low anterior hairline (HP:0000294)1.71084452
121Abnormality of incisor morphology (HP:0011063)1.70188000
122Cutis marmorata (HP:0000965)1.70090490
123Abnormality of the incisor (HP:0000676)1.68185565
124Bladder neoplasm (HP:0009725)1.67845132
125Bladder carcinoma (HP:0002862)1.67845132
126Germ cell neoplasia (HP:0100728)1.67747824
127Aplastic anemia (HP:0001915)1.67076244
128Hypoglycemic seizures (HP:0002173)1.66270742
129Narrow palate (HP:0000189)1.66113118
130Esophageal varix (HP:0002040)1.65727044
131Capillary hemangiomas (HP:0005306)1.65347613
132Leiomyosarcoma (HP:0100243)1.65342213
133Uterine leiomyosarcoma (HP:0002891)1.65342213
134Barrel-shaped chest (HP:0001552)1.64912234
135Gastrointestinal infarctions (HP:0005244)1.64208480
136Hypergonadotropic hypogonadism (HP:0000815)1.63466045
137Abnormality of DNA repair (HP:0003254)1.63399836
138Abnormality of the ileum (HP:0001549)1.63114207
139Embryonal renal neoplasm (HP:0011794)1.62950438
140Abnormality of the renal medulla (HP:0100957)1.62840200
141Neoplasm of the tracheobronchial system (HP:0100552)1.62308948
142Supernumerary bones of the axial skeleton (HP:0009144)1.61574626
143Gastrointestinal inflammation (HP:0004386)1.61421381
144Thick eyebrow (HP:0000574)1.61333408
145Periodontitis (HP:0000704)1.61229723
146Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.61031786
147Absent speech (HP:0001344)1.60878875
148Osteomyelitis (HP:0002754)1.60232446
149Myelodysplasia (HP:0002863)1.59845188
150Meningitis (HP:0001287)1.59767367
151Hamartoma (HP:0010566)1.59589294
152Spinal cord lesions (HP:0100561)1.58477648
153Syringomyelia (HP:0003396)1.58477648
154Recurrent cutaneous fungal infections (HP:0011370)1.58473183
155Chronic mucocutaneous candidiasis (HP:0002728)1.58473183
156Symptomatic seizures (HP:0011145)1.58038333
157Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.57907992
158Conjugated hyperbilirubinemia (HP:0002908)1.55946296
159Azoospermia (HP:0000027)1.55427170
160Abnormality of the frontal sinuses (HP:0002687)1.53226856
161Orchitis (HP:0100796)1.53179219
162Myositis (HP:0100614)1.52620237
163Gastrointestinal stroma tumor (HP:0100723)1.52418400
164Recurrent bacterial skin infections (HP:0005406)1.51604390
165Lymphopenia (HP:0001888)1.51127191
166Gingival bleeding (HP:0000225)1.50890991
167Cellulitis (HP:0100658)1.50358091

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS14.16694710
2FRK2.68204732
3BRD42.67210568
4NUAK12.60055100
5TAOK32.53391920
6CDK122.51264588
7INSRR2.50309338
8CAMKK22.45935539
9MAP3K102.44058647
10ZAK2.31544716
11AKT32.00855438
12STK31.97614376
13MARK31.87674996
14TGFBR21.80615781
15MAP3K141.80083862
16MAP3K131.68126980
17IRAK41.65544558
18EIF2AK31.63808236
19TTK1.63082990
20TIE11.54517012
21MAP3K41.54033303
22CDK91.52064550
23MKNK21.50342305
24STK381.48213285
25CHUK1.47792988
26CDC71.47308819
27KIT1.43191229
28PINK11.42844034
29IRAK11.37804243
30IKBKE1.37291192
31STK41.33430765
32ERBB31.33155032
33CSF1R1.31714363
34PLK41.28870045
35IRAK31.28602646
36MAP4K11.26860314
37STK101.26856022
38FLT31.25553295
39CAMK1D1.24898407
40MAP3K61.22244334
41NLK1.20628006
42JAK31.19384321
43NEK91.16412040
44MKNK11.14955514
45SRPK11.14282447
46NEK21.13623965
47TEC1.13515720
48MELK1.11135482
49TYK21.06785036
50BTK1.06775118
51SGK21.05664768
52YES11.04686193
53EEF2K1.04432059
54FGFR31.02252636
55SIK11.00480215
56PTK61.00200819
57PASK0.99431487
58IKBKB0.97888465
59CAMK1G0.96659252
60ATR0.96389236
61CDK60.96274819
62SGK4940.94772267
63SGK2230.94772267
64EPHA30.94261177
65CDK70.94158790
66HCK0.93856880
67PIK3CG0.93473326
68RPS6KB20.90597489
69ERBB40.88001260
70CHEK20.87795525
71PRPF4B0.86628828
72HIPK20.85676597
73STK38L0.84604787
74CAMK40.84387158
75SGK30.84161496
76STK110.83614784
77CDK30.79579374
78TGFBR10.79556492
79JAK10.78902081
80PIM10.77955517
81MUSK0.77499261
82MAP3K70.76181493
83PRKAA20.75477868
84DMPK0.75042240
85MAP2K40.74964120
86ATM0.74389702
87TAF10.74151582
88RPS6KA40.73186385
89WNK10.71946383
90LYN0.71718065
91TLK10.70341356
92EIF2AK20.69391257
93GRK10.69326762
94BRSK20.69280218
95FGFR20.68878796
96KSR10.68743814
97TNK20.68303935
98RET0.67873514
99ITK0.67729216
100DYRK30.66874489
101CASK0.65494424
102CAMKK10.65408855
103IRAK20.65106581
104ACVR1B0.64067210
105ZAP700.63905695
106CSK0.63635377
107BLK0.63607846
108SYK0.61904362
109FES0.61742465
110MAP2K70.61609007
111TXK0.60717046
112VRK10.59568189
113MAPK150.59270926
114JAK20.57865148
115AURKB0.57451935
116WNK30.57258040
117ABL10.56176294
118AKT10.55542688
119TRPM70.53775659
120MAP3K20.53476932
121CDK40.52435802
122PDGFRB0.51848743
123PIK3CA0.51532695
124STK240.51254578
125KDR0.50453605
126RPS6KB10.50173695
127RPS6KA60.49768280
128FGR0.48336171
129MAP2K30.47956378
130MATK0.47715812
131PRKD20.47069635
132CSNK1A1L0.46776948
133EPHB20.45224309
134RIPK40.44819836
135TNIK0.44759524
136PLK10.44613800
137BMPR1B0.44018562
138LCK0.43883831
139EPHB10.42630489
140PKN20.42530934
141MAPK70.42283294
142PRKCQ0.42006172

Predicted pathways (KEGG)

RankGene SetZ-score
1Non-homologous end-joining_Homo sapiens_hsa034502.46167229
2Maturity onset diabetes of the young_Homo sapiens_hsa049502.21942021
3T cell receptor signaling pathway_Homo sapiens_hsa046602.06484455
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.00194673
5Transcriptional misregulation in cancer_Homo sapiens_hsa052021.79727520
6Caffeine metabolism_Homo sapiens_hsa002321.75576230
7Dorso-ventral axis formation_Homo sapiens_hsa043201.69946516
8Herpes simplex infection_Homo sapiens_hsa051681.61188179
9Adherens junction_Homo sapiens_hsa045201.60788497
10Fanconi anemia pathway_Homo sapiens_hsa034601.59613175
11B cell receptor signaling pathway_Homo sapiens_hsa046621.56859485
12Lysine degradation_Homo sapiens_hsa003101.56564280
13Cell cycle_Homo sapiens_hsa041101.54793955
14Primary immunodeficiency_Homo sapiens_hsa053401.51164206
15RNA degradation_Homo sapiens_hsa030181.46905651
16Hematopoietic cell lineage_Homo sapiens_hsa046401.41934266
17Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.38894937
18MicroRNAs in cancer_Homo sapiens_hsa052061.38839826
19TGF-beta signaling pathway_Homo sapiens_hsa043501.38111919
20Systemic lupus erythematosus_Homo sapiens_hsa053221.37694028
21Renal cell carcinoma_Homo sapiens_hsa052111.34669759
22Small cell lung cancer_Homo sapiens_hsa052221.33982878
23Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.33912564
24Leishmaniasis_Homo sapiens_hsa051401.32738980
25Homologous recombination_Homo sapiens_hsa034401.32515476
26NOD-like receptor signaling pathway_Homo sapiens_hsa046211.30094164
27Toll-like receptor signaling pathway_Homo sapiens_hsa046201.28688518
28Measles_Homo sapiens_hsa051621.28600929
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.26673906
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.25008757
31Prostate cancer_Homo sapiens_hsa052151.24704925
32mTOR signaling pathway_Homo sapiens_hsa041501.24523480
33Phosphatidylinositol signaling system_Homo sapiens_hsa040701.24118684
34Staphylococcus aureus infection_Homo sapiens_hsa051501.21962376
35Pancreatic cancer_Homo sapiens_hsa052121.21750411
36Chronic myeloid leukemia_Homo sapiens_hsa052201.20227866
37RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.19999035
38p53 signaling pathway_Homo sapiens_hsa041151.13682729
39Other glycan degradation_Homo sapiens_hsa005111.13177022
40Osteoclast differentiation_Homo sapiens_hsa043801.12636229
41Neurotrophin signaling pathway_Homo sapiens_hsa047221.10268368
42Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.08618279
43Antigen processing and presentation_Homo sapiens_hsa046121.07548839
44Intestinal immune network for IgA production_Homo sapiens_hsa046721.05018847
45Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.04741678
46Toxoplasmosis_Homo sapiens_hsa051451.03224941
47Choline metabolism in cancer_Homo sapiens_hsa052311.02463950
48Hepatitis B_Homo sapiens_hsa051611.02433648
49Influenza A_Homo sapiens_hsa051641.02020868
50VEGF signaling pathway_Homo sapiens_hsa043700.98446340
51FoxO signaling pathway_Homo sapiens_hsa040680.97250083
52Prolactin signaling pathway_Homo sapiens_hsa049170.96991044
53Basal cell carcinoma_Homo sapiens_hsa052170.96613489
54Renin secretion_Homo sapiens_hsa049240.94989607
55Notch signaling pathway_Homo sapiens_hsa043300.94852733
56Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.94400094
57Mismatch repair_Homo sapiens_hsa034300.93098656
58Jak-STAT signaling pathway_Homo sapiens_hsa046300.92054007
59Viral carcinogenesis_Homo sapiens_hsa052030.92010114
60Sphingolipid signaling pathway_Homo sapiens_hsa040710.91389586
61Circadian rhythm_Homo sapiens_hsa047100.87765346
62mRNA surveillance pathway_Homo sapiens_hsa030150.87395916
63Type II diabetes mellitus_Homo sapiens_hsa049300.87209358
64ErbB signaling pathway_Homo sapiens_hsa040120.87055753
65Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.86865570
66Regulation of autophagy_Homo sapiens_hsa041400.86089577
67Colorectal cancer_Homo sapiens_hsa052100.84563127
68TNF signaling pathway_Homo sapiens_hsa046680.84402254
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.83890231
70Leukocyte transendothelial migration_Homo sapiens_hsa046700.82783584
71Long-term depression_Homo sapiens_hsa047300.82628096
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.82439843
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.81724631
74Pathways in cancer_Homo sapiens_hsa052000.81665192
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.80911233
76Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80867924
77Base excision repair_Homo sapiens_hsa034100.80711710
78Longevity regulating pathway - mammal_Homo sapiens_hsa042110.80536569
79Glioma_Homo sapiens_hsa052140.79063174
80Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.78985774
81Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78401058
82Chemokine signaling pathway_Homo sapiens_hsa040620.77981120
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.77040842
84Platelet activation_Homo sapiens_hsa046110.76986614
85MAPK signaling pathway_Homo sapiens_hsa040100.75999248
86Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75486406
87HTLV-I infection_Homo sapiens_hsa051660.74713719
88Basal transcription factors_Homo sapiens_hsa030220.73595932
89One carbon pool by folate_Homo sapiens_hsa006700.72393247
90Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72242827
91Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71843741
92Apoptosis_Homo sapiens_hsa042100.71590107
93Starch and sucrose metabolism_Homo sapiens_hsa005000.70885921
94N-Glycan biosynthesis_Homo sapiens_hsa005100.70847987
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.69964702
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.69898818
97Hepatitis C_Homo sapiens_hsa051600.68883340
98Endometrial cancer_Homo sapiens_hsa052130.68430352
99ABC transporters_Homo sapiens_hsa020100.67960788
100Acute myeloid leukemia_Homo sapiens_hsa052210.66945654
101Wnt signaling pathway_Homo sapiens_hsa043100.66896542
102Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65431674
103Ovarian steroidogenesis_Homo sapiens_hsa049130.64818036
104Non-small cell lung cancer_Homo sapiens_hsa052230.64785665
105Selenocompound metabolism_Homo sapiens_hsa004500.62077930
106Adipocytokine signaling pathway_Homo sapiens_hsa049200.62068948
107Pertussis_Homo sapiens_hsa051330.61480326
108Tuberculosis_Homo sapiens_hsa051520.61000639
109Vascular smooth muscle contraction_Homo sapiens_hsa042700.60449453
110Proteoglycans in cancer_Homo sapiens_hsa052050.60447636
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.60278135
112Complement and coagulation cascades_Homo sapiens_hsa046100.59504169
113Thyroid cancer_Homo sapiens_hsa052160.59323607
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58782435
115DNA replication_Homo sapiens_hsa030300.58701674
116Ether lipid metabolism_Homo sapiens_hsa005650.58648496
117Hippo signaling pathway_Homo sapiens_hsa043900.58553729
118GnRH signaling pathway_Homo sapiens_hsa049120.57980280
119Shigellosis_Homo sapiens_hsa051310.57880732
120Vitamin digestion and absorption_Homo sapiens_hsa049770.57064731
121Phospholipase D signaling pathway_Homo sapiens_hsa040720.56882491
122Melanoma_Homo sapiens_hsa052180.56150033
123Legionellosis_Homo sapiens_hsa051340.55957350
124Alcoholism_Homo sapiens_hsa050340.55883757
125Phototransduction_Homo sapiens_hsa047440.55720483
126Linoleic acid metabolism_Homo sapiens_hsa005910.55624790
127Malaria_Homo sapiens_hsa051440.55567256
128Ras signaling pathway_Homo sapiens_hsa040140.54650722
129Insulin resistance_Homo sapiens_hsa049310.53127827
130cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51491776
131Graft-versus-host disease_Homo sapiens_hsa053320.51217509
132Serotonergic synapse_Homo sapiens_hsa047260.51212338
133Sphingolipid metabolism_Homo sapiens_hsa006000.50286856
134Viral myocarditis_Homo sapiens_hsa054160.49294630
135Inositol phosphate metabolism_Homo sapiens_hsa005620.49046626
136PI3K-Akt signaling pathway_Homo sapiens_hsa041510.46979068

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »