DENND6B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)8.70865609
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.23954727
3cilium movement (GO:0003341)8.11130075
4epithelial cilium movement (GO:0003351)7.42110078
5motile cilium assembly (GO:0044458)6.85018343
6regulation of short-term neuronal synaptic plasticity (GO:0048172)6.18327319
7axoneme assembly (GO:0035082)6.02972885
8synaptic vesicle maturation (GO:0016188)5.98855404
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.73843883
10locomotory exploration behavior (GO:0035641)5.51622852
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.47268926
12response to pheromone (GO:0019236)5.38600879
13vocalization behavior (GO:0071625)5.37634984
14synaptic vesicle exocytosis (GO:0016079)5.35752791
15regulation of cilium movement (GO:0003352)5.19120912
16regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.13022178
17synaptic vesicle docking involved in exocytosis (GO:0016081)4.96999815
18regulation of synaptic vesicle exocytosis (GO:2000300)4.96397768
19glutamate secretion (GO:0014047)4.87188497
20neuron cell-cell adhesion (GO:0007158)4.77830875
21ionotropic glutamate receptor signaling pathway (GO:0035235)4.72368305
22regulation of glutamate receptor signaling pathway (GO:1900449)4.67205327
23left/right pattern formation (GO:0060972)4.64671173
24protein localization to synapse (GO:0035418)4.63989527
25neuronal action potential propagation (GO:0019227)4.62498205
26positive regulation of synapse maturation (GO:0090129)4.59436320
27neurotransmitter secretion (GO:0007269)4.58114743
28cellular potassium ion homeostasis (GO:0030007)4.46531594
29regulation of microtubule-based movement (GO:0060632)4.41911729
30glutamate receptor signaling pathway (GO:0007215)4.41619073
31synaptic transmission, glutamatergic (GO:0035249)4.41334975
32regulation of synaptic vesicle transport (GO:1902803)4.38639983
33cerebellar Purkinje cell differentiation (GO:0021702)4.37706501
34pyrimidine nucleobase catabolic process (GO:0006208)4.31017800
35neurotransmitter-gated ion channel clustering (GO:0072578)4.23612289
36layer formation in cerebral cortex (GO:0021819)4.23438569
37G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.16268959
38sodium ion export (GO:0071436)4.12790335
39regulation of synapse structural plasticity (GO:0051823)4.12514824
40exploration behavior (GO:0035640)4.12373212
41microtubule bundle formation (GO:0001578)4.09519995
42regulation of neuronal synaptic plasticity (GO:0048168)4.08269965
43neuron-neuron synaptic transmission (GO:0007270)4.04167164
44gamma-aminobutyric acid transport (GO:0015812)4.00838086
45membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.00432594
46regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.98012980
47long-term memory (GO:0007616)3.94922202
48regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.93967496
49neuromuscular process controlling posture (GO:0050884)3.93361555
50intraciliary transport (GO:0042073)3.85402015
51membrane depolarization during action potential (GO:0086010)3.83809669
52regulation of long-term neuronal synaptic plasticity (GO:0048169)3.81503380
53synaptic vesicle endocytosis (GO:0048488)3.81444529
54cell communication by electrical coupling (GO:0010644)3.78571751
55protein localization to cilium (GO:0061512)3.77068203
56positive regulation of membrane potential (GO:0045838)3.76439213
57cilium organization (GO:0044782)3.74909936
58cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.74138124
59cilium assembly (GO:0042384)3.70654295
60regulation of excitatory postsynaptic membrane potential (GO:0060079)3.68986126
61dendritic spine morphogenesis (GO:0060997)3.68038617
62neurotransmitter transport (GO:0006836)3.66797564
63positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.65715878
64regulation of synapse maturation (GO:0090128)3.65430036
65establishment of mitochondrion localization (GO:0051654)3.65019657
66cerebellar granule cell differentiation (GO:0021707)3.64320540
67neuron recognition (GO:0008038)3.62638694
68positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.61963688
69axonal fasciculation (GO:0007413)3.60022088
70regulation of postsynaptic membrane potential (GO:0060078)3.55775059
71axon ensheathment in central nervous system (GO:0032291)3.54438552
72central nervous system myelination (GO:0022010)3.54438552
73gamma-aminobutyric acid signaling pathway (GO:0007214)3.53462392
74transmission of nerve impulse (GO:0019226)3.45760971
75membrane hyperpolarization (GO:0060081)3.44962890
76prepulse inhibition (GO:0060134)3.44049513
77regulation of neurotransmitter secretion (GO:0046928)3.43439673
78nucleobase catabolic process (GO:0046113)3.40211991
79dendrite morphogenesis (GO:0048813)3.39931550
80auditory behavior (GO:0031223)3.39697763
81regulation of neurotransmitter levels (GO:0001505)3.36901300
82neuromuscular process controlling balance (GO:0050885)3.36150062
83regulation of synaptic transmission, glutamatergic (GO:0051966)3.35440947
84membrane depolarization (GO:0051899)3.35096124
85response to auditory stimulus (GO:0010996)3.33553135
86regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.28998444
87positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.28548522
88regulation of synaptic plasticity (GO:0048167)3.27453524
89ventricular system development (GO:0021591)3.26920208
90positive regulation of synaptic transmission, GABAergic (GO:0032230)3.26234356
91cell differentiation in hindbrain (GO:0021533)3.25303343
92postsynaptic membrane organization (GO:0001941)3.24655014
93long-term synaptic potentiation (GO:0060291)3.23601912
94activation of protein kinase A activity (GO:0034199)3.23091790
95cell migration in hindbrain (GO:0021535)3.22028701
96positive regulation of potassium ion transmembrane transport (GO:1901381)3.21818018
97establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.20857210
98mitochondrion transport along microtubule (GO:0047497)3.20857210
99potassium ion homeostasis (GO:0055075)3.20061675
100microtubule-based movement (GO:0007018)3.19212139
101neuronal ion channel clustering (GO:0045161)3.16341547
102adult walking behavior (GO:0007628)3.16014616
103regulation of dendritic spine morphogenesis (GO:0061001)3.15323531
104regulation of neurotransmitter transport (GO:0051588)3.15189137
105regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.14476279
106behavioral response to nicotine (GO:0035095)3.10801899
107left/right axis specification (GO:0070986)3.06154405
108regulation of respiratory system process (GO:0044065)3.04795930
109striatum development (GO:0021756)3.04360750
110nonmotile primary cilium assembly (GO:0035058)3.04180261
111potassium ion import (GO:0010107)3.03361754
112negative regulation of synaptic transmission, GABAergic (GO:0032229)3.01887572
113neuromuscular process (GO:0050905)3.00517050
114positive regulation of neurotransmitter transport (GO:0051590)3.00454079
115synapse assembly (GO:0007416)3.00088070
116cerebellar Purkinje cell layer development (GO:0021680)2.99798478
117regulation of vesicle fusion (GO:0031338)2.99706205
118cellular component assembly involved in morphogenesis (GO:0010927)2.99324420
119glycine transport (GO:0015816)2.99245720
120proline transport (GO:0015824)2.98664195
121positive regulation of dendritic spine morphogenesis (GO:0061003)2.97836643
122behavioral response to cocaine (GO:0048148)2.97379988
123mechanosensory behavior (GO:0007638)2.97132211
124positive regulation of neurotransmitter secretion (GO:0001956)2.97030417
125protein polyglutamylation (GO:0018095)2.96191286
126membrane repolarization (GO:0086009)2.95971309
127learning (GO:0007612)2.93543419
128negative regulation of cytosolic calcium ion concentration (GO:0051481)2.93177805
129cilium morphogenesis (GO:0060271)2.81174115
130lung epithelium development (GO:0060428)2.75118813
131dendritic spine organization (GO:0097061)2.74677640
132neurotransmitter catabolic process (GO:0042135)2.69178715
133positive regulation of synapse assembly (GO:0051965)2.62718381
134sperm motility (GO:0030317)2.59344431
135negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.58938905
136neuromuscular synaptic transmission (GO:0007274)2.57219600
137cell projection assembly (GO:0030031)2.55038790
138ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.54658778
139presynaptic membrane organization (GO:0097090)2.49535076
140regulation of voltage-gated calcium channel activity (GO:1901385)2.48279292
141retinal cone cell development (GO:0046549)2.47528717
142adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.44706918
143negative regulation of axonogenesis (GO:0050771)2.42709983
144axonemal dynein complex assembly (GO:0070286)10.5869698

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.75688590
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.32849277
3GBX2_23144817_ChIP-Seq_PC3_Human2.99945306
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98943709
5REST_21632747_ChIP-Seq_MESCs_Mouse2.95415172
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.95329800
7JARID2_20064375_ChIP-Seq_MESCs_Mouse2.88708930
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.85226996
9DROSHA_22980978_ChIP-Seq_HELA_Human2.83526418
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.66851453
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.66851453
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.64850944
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.63704512
14IKZF1_21737484_ChIP-ChIP_HCT116_Human2.56632981
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.56092924
16REST_18959480_ChIP-ChIP_MESCs_Mouse2.53542501
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.50362479
18EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.50019676
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.47308076
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.43963701
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.41536114
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.40804280
23MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.38588273
24SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.34195815
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31550398
26TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.25040777
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.24163266
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.22549932
29RNF2_27304074_Chip-Seq_ESCs_Mouse2.19576677
30EED_16625203_ChIP-ChIP_MESCs_Mouse2.07732929
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.03602593
32ZNF274_21170338_ChIP-Seq_K562_Hela1.68764496
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.67775628
34DNAJC2_21179169_ChIP-ChIP_NT2_Human1.58992862
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52168115
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50756433
37RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.46509862
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.43679840
39TAF15_26573619_Chip-Seq_HEK293_Human1.43601745
40CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.41326115
41AR_21572438_ChIP-Seq_LNCaP_Human1.39270059
42P68_20966046_ChIP-Seq_HELA_Human1.36892776
43PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.35541316
44ZFP281_18757296_ChIP-ChIP_E14_Mouse1.34318432
45SMAD4_21799915_ChIP-Seq_A2780_Human1.33754293
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.33574562
47KDM2B_26808549_Chip-Seq_K562_Human1.32152595
48EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.31752716
49RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.30560915
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27001379
51AR_19668381_ChIP-Seq_PC3_Human1.26133227
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21777573
53P53_22127205_ChIP-Seq_FIBROBLAST_Human1.21470479
54GATA1_26923725_Chip-Seq_HPCs_Mouse1.19631388
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.18949033
56SOX2_21211035_ChIP-Seq_LN229_Gbm1.17481874
57RING1B_27294783_Chip-Seq_NPCs_Mouse1.15249305
58ELF1_20517297_ChIP-Seq_JURKAT_Human1.13024416
59PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.12566130
60BCL6_27268052_Chip-Seq_Bcells_Human1.12054723
61RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.11211800
62WT1_25993318_ChIP-Seq_PODOCYTE_Human1.10996487
63GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10401885
64SRY_22984422_ChIP-ChIP_TESTIS_Rat1.09805177
65CTCF_20526341_ChIP-Seq_ESCs_Human1.09731986
66AR_25329375_ChIP-Seq_VCAP_Human1.07963071
67OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07823396
68SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.06546201
69TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.05709447
70WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.05352975
71ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.04702689
72CTCF_27219007_Chip-Seq_Bcells_Human1.04501453
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04272235
74NR3C1_23031785_ChIP-Seq_PC12_Mouse1.01476516
75MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01470777
76STAT3_23295773_ChIP-Seq_U87_Human1.01001105
77VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00188931
78THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.00062036
79EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99480011
80GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99214714
81TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98793107
82SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.97952182
83PHF8_20622854_ChIP-Seq_HELA_Human0.97951120
84TET1_21490601_ChIP-Seq_MESCs_Mouse0.97802144
85RNF2_27304074_Chip-Seq_NSC_Mouse0.97306491
86SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97296458
87SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97241955
88ZFP281_27345836_Chip-Seq_ESCs_Mouse0.96950674
89SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96269460
90E2F1_20622854_ChIP-Seq_HELA_Human0.95430942
91SMAD3_21741376_ChIP-Seq_EPCs_Human0.94576300
92SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93733998
93ERA_21632823_ChIP-Seq_H3396_Human0.93675868
94ZFP57_27257070_Chip-Seq_ESCs_Mouse0.93595830
95SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.93027178
96P300_19829295_ChIP-Seq_ESCs_Human0.92519551
97SMAD3_21741376_ChIP-Seq_ESCs_Human0.91828345
98TCF4_23295773_ChIP-Seq_U87_Human0.91762564
99RAD21_21589869_ChIP-Seq_MESCs_Mouse0.90230719
100BCOR_27268052_Chip-Seq_Bcells_Human0.89996756
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89766766
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89766766
103TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89661316
104YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89424986
105SA1_27219007_Chip-Seq_Bcells_Human0.89407059
106SMC4_20622854_ChIP-Seq_HELA_Human0.89307241
107TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.88827000
108TP63_22573176_ChIP-Seq_HFKS_Human0.88596930
109CREB1_26743006_Chip-Seq_LNCaP_Human0.87631167
110YY1_22570637_ChIP-Seq_MALME-3M_Human0.87540546
111TAF2_19829295_ChIP-Seq_ESCs_Human0.87397017
112RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87158636
113DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86257335
114KDM2B_26808549_Chip-Seq_SUP-B15_Human0.85768546
115TP53_20018659_ChIP-ChIP_R1E_Mouse0.85383939
116ARNT_22903824_ChIP-Seq_MCF-7_Human0.85032942
117SA1_27219007_Chip-Seq_ERYTHROID_Human0.84398941
118TOP2B_26459242_ChIP-Seq_MCF-7_Human0.83546230
119MYC_19829295_ChIP-Seq_ESCs_Human0.83193084
120IRF1_19129219_ChIP-ChIP_H3396_Human0.82893080
121ETV2_25802403_ChIP-Seq_MESCs_Mouse0.82807429
122RUNX2_22187159_ChIP-Seq_PCA_Human0.82655773
123SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.82103921
124CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.81977978
125AHR_22903824_ChIP-Seq_MCF-7_Human0.80969339
126OCT4_20526341_ChIP-Seq_ESCs_Human0.80825133
127SMAD4_21741376_ChIP-Seq_HESCs_Human0.80017735
128TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79591377
129KLF4_19829295_ChIP-Seq_ESCs_Human0.77710511
130MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.77353339
131TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.76609968
132LXR_22292898_ChIP-Seq_THP-1_Human0.76559020
133OCT4_19829295_ChIP-Seq_ESCs_Human0.76093712

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.91770721
2MP0003880_abnormal_central_pattern4.30711998
3MP0003635_abnormal_synaptic_transmissio3.96892858
4MP0005423_abnormal_somatic_nervous3.38409298
5MP0009046_muscle_twitch3.36393641
6MP0004270_analgesia3.27328923
7MP0009745_abnormal_behavioral_response3.19845872
8MP0002063_abnormal_learning/memory/cond3.08605070
9MP0002064_seizures3.02927795
10MP0002822_catalepsy2.84222993
11MP0001968_abnormal_touch/_nociception2.77800365
12MP0002572_abnormal_emotion/affect_behav2.64584149
13MP0002272_abnormal_nervous_system2.61911421
14MP0001486_abnormal_startle_reflex2.49988259
15MP0002734_abnormal_mechanical_nocicepti2.46347032
16MP0008569_lethality_at_weaning2.26204640
17MP0002067_abnormal_sensory_capabilities2.11023903
18MP0002736_abnormal_nociception_after2.10765241
19MP0002184_abnormal_innervation2.05153378
20MP0001501_abnormal_sleep_pattern2.04196198
21MP0001984_abnormal_olfaction2.00714090
22MP0001440_abnormal_grooming_behavior1.95663786
23MP0002735_abnormal_chemical_nociception1.91212563
24MP0006276_abnormal_autonomic_nervous1.88171015
25MP0002733_abnormal_thermal_nociception1.87843721
26MP0004133_heterotaxia1.87557849
27MP0008875_abnormal_xenobiotic_pharmacok1.85460204
28MP0005551_abnormal_eye_electrophysiolog1.84359498
29MP0002909_abnormal_adrenal_gland1.82979838
30MP0000778_abnormal_nervous_system1.81721600
31MP0002557_abnormal_social/conspecific_i1.79936409
32MP0005645_abnormal_hypothalamus_physiol1.79075131
33MP0001970_abnormal_pain_threshold1.78560449
34MP0003787_abnormal_imprinting1.77589481
35MP0003122_maternal_imprinting1.76048366
36MP0001502_abnormal_circadian_rhythm1.71312398
37MP0004811_abnormal_neuron_physiology1.71191188
38MP0004924_abnormal_behavior1.70519802
39MP0005386_behavior/neurological_phenoty1.70519802
40MP0004145_abnormal_muscle_electrophysio1.68671156
41MP0003879_abnormal_hair_cell1.61365701
42MP0000751_myopathy1.59496893
43MP0000955_abnormal_spinal_cord1.59007252
44MP0005646_abnormal_pituitary_gland1.57241239
45MP0002882_abnormal_neuron_morphology1.56199806
46MP0003329_amyloid_beta_deposits1.52606066
47MP0001529_abnormal_vocalization1.49962085
48MP0004142_abnormal_muscle_tone1.47894793
49MP0004043_abnormal_pH_regulation1.46328260
50MP0002066_abnormal_motor_capabilities/c1.43914428
51MP0008789_abnormal_olfactory_epithelium1.43638505
52MP0004885_abnormal_endolymph1.31312970
53MP0003878_abnormal_ear_physiology1.26775791
54MP0005377_hearing/vestibular/ear_phenot1.26775791
55MP0001986_abnormal_taste_sensitivity1.25485171
56MP0009780_abnormal_chondrocyte_physiolo1.24114514
57MP0004858_abnormal_nervous_system1.24029884
58MP0006072_abnormal_retinal_apoptosis1.21164170
59MP0000026_abnormal_inner_ear1.21137652
60MP0003633_abnormal_nervous_system1.20889785
61MP0002152_abnormal_brain_morphology1.20307776
62MP0002653_abnormal_ependyma_morphology1.19837304
63MP0002229_neurodegeneration1.17337898
64MP0002638_abnormal_pupillary_reflex1.15963856
65MP0000566_synostosis1.14741257
66MP0002928_abnormal_bile_duct1.11667765
67MP0000569_abnormal_digit_pigmentation1.10677280
68MP0008961_abnormal_basal_metabolism1.08482756
69MP0004233_abnormal_muscle_weight1.04525030
70MP0001905_abnormal_dopamine_level1.04017601
71MP0004742_abnormal_vestibular_system1.03908139
72MP0005394_taste/olfaction_phenotype1.03874653
73MP0005499_abnormal_olfactory_system1.03874653
74MP0003283_abnormal_digestive_organ1.03869679
75MP0003631_nervous_system_phenotype1.03217519
76MP0002752_abnormal_somatic_nervous1.02660442
77MP0005167_abnormal_blood-brain_barrier1.01397615
78MP0003137_abnormal_impulse_conducting1.01067832
79MP0005253_abnormal_eye_physiology0.99479019
80MP0002069_abnormal_eating/drinking_beha0.98997158
81MP0005083_abnormal_biliary_tract0.98166392
82MP0004085_abnormal_heartbeat0.95044222
83MP0008877_abnormal_DNA_methylation0.94193002
84MP0004215_abnormal_myocardial_fiber0.93885334
85MP0000631_abnormal_neuroendocrine_gland0.93238343
86MP0008872_abnormal_physiological_respon0.91977294
87MP0003136_yellow_coat_color0.90865645
88MP0003011_delayed_dark_adaptation0.90749325
89MP0006292_abnormal_olfactory_placode0.85530767
90MP0003121_genomic_imprinting0.81432467
91MP0002234_abnormal_pharynx_morphology0.80629193
92MP0002160_abnormal_reproductive_system0.80035730
93MP0002090_abnormal_vision0.79080138
94MP0001963_abnormal_hearing_physiology0.78218239
95MP0003938_abnormal_ear_development0.77898237
96MP0002876_abnormal_thyroid_physiology0.77846474
97MP0003632_abnormal_nervous_system0.76673807
98MP0003861_abnormal_nervous_system0.73777474
99MP0003634_abnormal_glial_cell0.73002823
100MP0002837_dystrophic_cardiac_calcinosis0.72574996
101MP0009379_abnormal_foot_pigmentation0.71525594
102MP0002102_abnormal_ear_morphology0.71220752
103MP0002277_abnormal_respiratory_mucosa0.70474799
104MP0008874_decreased_physiological_sensi0.70318260
105MP0005084_abnormal_gallbladder_morpholo0.69480456
106MP0003698_abnormal_male_reproductive0.69223089
107MP0010386_abnormal_urinary_bladder0.69188520
108MP0003646_muscle_fatigue0.68896690
109MP0001485_abnormal_pinna_reflex0.67345869
110MP0003183_abnormal_peptide_metabolism0.66068511
111MP0000604_amyloidosis0.65729871
112MP0005535_abnormal_body_temperature0.65486051
113MP0003172_abnormal_lysosome_physiology0.65455454
114MP0010769_abnormal_survival0.64145298
115MP0001177_atelectasis0.64063684
116MP0002249_abnormal_larynx_morphology0.63813331
117MP0001765_abnormal_ion_homeostasis0.63196740
118MP0001188_hyperpigmentation0.62552709
119MP0010770_preweaning_lethality0.62123085
120MP0002082_postnatal_lethality0.62123085
121MP0000013_abnormal_adipose_tissue0.61430302
122MP0010768_mortality/aging0.61239076
123MP0000747_muscle_weakness0.61216343
124MP0003123_paternal_imprinting0.60629735
125MP0003690_abnormal_glial_cell0.60398245
126MP0005410_abnormal_fertilization0.60387330
127MP0005195_abnormal_posterior_eye0.60311793

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)8.47435638
2Abnormal respiratory epithelium morphology (HP:0012253)8.47435638
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)8.43900524
4Abnormal ciliary motility (HP:0012262)8.25141681
5Abnormal respiratory motile cilium physiology (HP:0012261)8.07963776
6Dynein arm defect of respiratory motile cilia (HP:0012255)8.06907503
7Absent/shortened dynein arms (HP:0200106)8.06907503
8Focal motor seizures (HP:0011153)6.95219714
9Rhinitis (HP:0012384)6.69066236
10Myokymia (HP:0002411)5.87647231
11Focal seizures (HP:0007359)5.64169929
12Visual hallucinations (HP:0002367)5.25913253
13Bronchiectasis (HP:0002110)5.02806108
14Chronic bronchitis (HP:0004469)4.95196864
15Febrile seizures (HP:0002373)4.78527349
16Epileptic encephalopathy (HP:0200134)4.67329326
17Progressive cerebellar ataxia (HP:0002073)4.66889636
18Atonic seizures (HP:0010819)4.51729376
19Nasal polyposis (HP:0100582)4.40463725
20Absence seizures (HP:0002121)4.30641814
21True hermaphroditism (HP:0010459)3.88131254
22Action tremor (HP:0002345)3.87511470
23Dialeptic seizures (HP:0011146)3.86011804
24Gaze-evoked nystagmus (HP:0000640)3.80585371
25Ankle clonus (HP:0011448)3.79619135
26Pancreatic fibrosis (HP:0100732)3.77879007
27Nephronophthisis (HP:0000090)3.62660807
28Abnormality of the nasal mucosa (HP:0000433)3.58537914
29Abnormality of midbrain morphology (HP:0002418)3.56370593
30Molar tooth sign on MRI (HP:0002419)3.56370593
31Broad-based gait (HP:0002136)3.56015174
32Generalized tonic-clonic seizures (HP:0002069)3.49143128
33Recurrent sinusitis (HP:0011108)3.46903679
34Dysdiadochokinesis (HP:0002075)3.44224939
35Infertility (HP:0000789)3.33373811
36Supranuclear gaze palsy (HP:0000605)3.29735390
37Truncal ataxia (HP:0002078)3.29567360
38Abnormality of the lower motor neuron (HP:0002366)3.22305854
39Pancreatic cysts (HP:0001737)3.22092387
40Cystic liver disease (HP:0006706)3.20592463
41Depression (HP:0000716)3.19982638
42Impaired vibration sensation in the lower limbs (HP:0002166)3.19572868
43Occipital encephalocele (HP:0002085)3.16195913
44Poor eye contact (HP:0000817)3.12816755
45Chronic sinusitis (HP:0011109)3.09993074
46Chronic hepatic failure (HP:0100626)3.07215334
47Hemiparesis (HP:0001269)3.05951071
48Abnormal social behavior (HP:0012433)3.00116825
49Impaired social interactions (HP:0000735)3.00116825
50Genetic anticipation (HP:0003743)2.98271141
51Medial flaring of the eyebrow (HP:0010747)2.92904941
52Urinary bladder sphincter dysfunction (HP:0002839)2.91065626
53Dysmetria (HP:0001310)2.89674799
54Abnormal eating behavior (HP:0100738)2.88911226
55Impaired smooth pursuit (HP:0007772)2.84945420
56Scanning speech (HP:0002168)2.84881976
57Dysmetric saccades (HP:0000641)2.81681502
58Hemiplegia (HP:0002301)2.79203155
59Abnormality of the renal medulla (HP:0100957)2.77723580
60Postural instability (HP:0002172)2.75272326
61Spastic gait (HP:0002064)2.74075123
62Congenital primary aphakia (HP:0007707)2.72625795
63Abnormality of ocular smooth pursuit (HP:0000617)2.71688669
64Anxiety (HP:0000739)2.69877859
65Urinary urgency (HP:0000012)2.69451128
66Central scotoma (HP:0000603)2.68003073
67Recurrent otitis media (HP:0000403)2.66529067
68Bronchitis (HP:0012387)2.65288937
69Status epilepticus (HP:0002133)2.60477088
70Nephrogenic diabetes insipidus (HP:0009806)2.55524939
71Ventricular fibrillation (HP:0001663)2.54411539
72Mutism (HP:0002300)2.50558103
73Progressive inability to walk (HP:0002505)2.46703661
74Congenital stationary night blindness (HP:0007642)2.42940573
75Polyphagia (HP:0002591)2.41384581
76Postaxial foot polydactyly (HP:0001830)2.40779156
77Hyperventilation (HP:0002883)2.40458119
78Excessive salivation (HP:0003781)2.39963526
79Drooling (HP:0002307)2.39963526
80Bradykinesia (HP:0002067)2.35072788
81Papilledema (HP:0001085)2.33185331
82Amblyopia (HP:0000646)2.32129506
83Atelectasis (HP:0100750)2.29994374
84Chronic otitis media (HP:0000389)2.29576133
85Clonus (HP:0002169)2.27978004
86Epileptiform EEG discharges (HP:0011182)2.27831496
87Intention tremor (HP:0002080)2.26586866
88Absent rod-and cone-mediated responses on ERG (HP:0007688)2.25362452
89Insomnia (HP:0100785)2.24106307
90Agitation (HP:0000713)2.23062196
91EEG with generalized epileptiform discharges (HP:0011198)2.22862220
92Torticollis (HP:0000473)2.22661715
93Lower limb muscle weakness (HP:0007340)2.22228328
94Specific learning disability (HP:0001328)2.19766916
95Anencephaly (HP:0002323)2.18725880
96Abnormal EKG (HP:0003115)2.16089260
97Neoplasm of the heart (HP:0100544)2.14865210
98Congenital hepatic fibrosis (HP:0002612)2.13109014
99Prolonged QT interval (HP:0001657)2.13065889
100Abnormality of binocular vision (HP:0011514)2.12597920
101Diplopia (HP:0000651)2.12597920
102Male infertility (HP:0003251)2.12110792
103Annular pancreas (HP:0001734)2.12106050
104Impaired vibratory sensation (HP:0002495)2.11266085
105Stereotypic behavior (HP:0000733)2.10950237
106Abnormality of the corticospinal tract (HP:0002492)2.09503536
107Pointed chin (HP:0000307)2.09191903
108Limb dystonia (HP:0002451)2.09002076
109Focal dystonia (HP:0004373)2.08399420
110Aplasia/Hypoplasia of the spleen (HP:0010451)2.08005392
111Failure to thrive in infancy (HP:0001531)2.06861324
112Hypsarrhythmia (HP:0002521)2.06509665
113Psychosis (HP:0000709)2.06441572
114Gait imbalance (HP:0002141)2.01814254
115Aplasia/Hypoplasia of the tongue (HP:0010295)2.01052647
116Asplenia (HP:0001746)2.00012979
117Exercise-induced myalgia (HP:0003738)1.99242143
118Abnormality of saccadic eye movements (HP:0000570)1.98378028
119Neuronal loss in central nervous system (HP:0002529)1.97374238
120Limb ataxia (HP:0002070)1.96993748
121Sclerocornea (HP:0000647)1.96736578
122Tubular atrophy (HP:0000092)1.96732946
123Sleep apnea (HP:0010535)1.96433330
124Vaginal atresia (HP:0000148)1.95425755
125Genital tract atresia (HP:0001827)1.95051189
126Hand muscle atrophy (HP:0009130)1.93559274
127Gait ataxia (HP:0002066)1.92356044
128Megalencephaly (HP:0001355)1.92102934
129Postaxial hand polydactyly (HP:0001162)1.89966850
130Amyotrophic lateral sclerosis (HP:0007354)1.88766580
131Tubulointerstitial nephritis (HP:0001970)1.88621659
132Craniofacial dystonia (HP:0012179)1.88256446
133Fetal akinesia sequence (HP:0001989)1.87206795
134Hypoventilation (HP:0002791)1.87162872
135Rigidity (HP:0002063)1.86462788
136Protruding tongue (HP:0010808)1.83795982
137Male pseudohermaphroditism (HP:0000037)1.83248267
138Absent speech (HP:0001344)1.83054718
139Abnormality of macular pigmentation (HP:0008002)1.81784748
140Scotoma (HP:0000575)1.80678487
141Poor coordination (HP:0002370)1.79693330
142Incomplete penetrance (HP:0003829)1.78606406
143Polydipsia (HP:0001959)1.77347514
144Abnormal drinking behavior (HP:0030082)1.77347514
145Generalized myoclonic seizures (HP:0002123)1.77245348
146Inability to walk (HP:0002540)1.76857101
147Anosmia (HP:0000458)1.76232221
148Pheochromocytoma (HP:0002666)1.76118256
149Bundle branch block (HP:0011710)1.75638885
150Tetraplegia (HP:0002445)1.73780533
151Spinal canal stenosis (HP:0003416)1.73494514
152Lissencephaly (HP:0001339)1.73012440
153Abnormal rod and cone electroretinograms (HP:0008323)1.71250760
154Nephropathy (HP:0000112)1.70676956
155Decreased circulating renin level (HP:0003351)1.65002969
156Obstructive sleep apnea (HP:0002870)1.63432328
157Decreased central vision (HP:0007663)1.62817301
158Narrow forehead (HP:0000341)1.58431494
159Retinitis pigmentosa (HP:0000510)1.58067657
160Hyperactive renin-angiotensin system (HP:0000841)1.57956976
161Aplasia/Hypoplasia of the brainstem (HP:0007362)1.49609441
162Hypoplasia of the brainstem (HP:0002365)1.49609441
163Short femoral neck (HP:0100864)1.49074060
164Preaxial hand polydactyly (HP:0001177)1.48577372

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK155.95025476
2NTRK34.44239195
3MAP3K93.55762534
4EPHA43.52562362
5MAP3K43.09055869
6MARK13.02649906
7NTRK22.62668238
8MINK12.59626806
9PAK62.58738759
10DAPK22.54150300
11MAP2K72.34876891
12KSR11.92766131
13PRKD31.91785838
14TNIK1.91624559
15SIK21.86499404
16CAMKK11.82780825
17KSR21.81822416
18MAPK131.81690619
19MAP2K41.79796225
20STK381.72693642
21MAP3K121.65995551
22CDK191.63426610
23PHKG11.60769763
24PHKG21.60769763
25UHMK11.59231911
26DYRK21.57004748
27CASK1.54410100
28TLK11.54004676
29PRPF4B1.52616854
30CDK51.48274952
31MAP4K21.41796627
32MAP3K111.39796790
33LMTK21.39698460
34DAPK11.36653415
35CAMKK21.31866315
36SIK31.30237434
37BCR1.29674409
38MAP3K131.29168434
39TYRO31.24677790
40WNK41.23103024
41PNCK1.19070713
42EPHB11.16573092
43INSRR1.14578351
44PRKCG1.13263001
45SGK2231.12468938
46SGK4941.12468938
47CAMK11.12007022
48FES1.11146278
49WNK31.11081127
50PRKCH1.09871069
51RIPK11.07303076
52EPHA31.04168875
53DYRK1B0.98220992
54DYRK1A0.96240727
55MARK20.95374142
56ADRBK20.94473325
57NTRK10.93958908
58SGK20.92804124
59CDK180.90883354
60GRK50.89791252
61PINK10.89577905
62TAOK10.88643221
63STK110.88128739
64CDK150.87009643
65ICK0.87006777
66CDC42BPA0.86584558
67RIPK40.81960085
68ARAF0.81848915
69PAK30.78315435
70CAMK2A0.78270533
71CAMK1G0.77936948
72SGK30.77935908
73CDK140.76820859
74CDK11A0.76488418
75MAP3K70.72374561
76WNK10.68726170
77BCKDK0.68319858
78TNK20.68206981
79CAMK40.65057320
80PLK20.64898192
81SGK10.64499821
82CAMK2B0.63830117
83CSNK1G20.63047106
84ALK0.62907376
85EPHB20.59323370
86MAPKAPK30.57309460
87RPS6KA30.56663363
88NEK10.54637724
89MAP3K10.52639209
90CSNK1G30.52018509
91RET0.51685872
92TAOK30.51278099
93MAPK100.49394168
94PRKACA0.48390892
95CAMK2D0.48374218
96PRKCQ0.48237771
97PRKCZ0.47887155
98PDK10.46846896
99MAP2K60.46580558
100PRKCI0.46369044
101GRK10.46298466
102RAF10.46085949
103CAMK2G0.45491741
104CSNK1A1L0.45333777
105OXSR10.42622644
106BRAF0.42618149
107PKN10.41633503
108RPS6KA20.41253473
109SYK0.41183189
110MAP3K60.40909380
111FYN0.40857284
112MAPKAPK50.40355608
113PRKD20.40012586
114MAP3K20.39172963
115MAPK120.37593071
116TBK10.37586703
117BTK0.37294488
118PRKCB0.37155949
119FGFR20.37098592
120NME10.36883844
121PDPK10.36411264
122MATK0.36029506
123PTK2B0.35201639
124TESK10.35196392
125MAPK80.34963812
126PRKCA0.34846200
127CSNK1E0.34663449
128CSF1R0.33906689
129PIM20.33686208
130ERBB20.33232170
131DAPK30.32912956
132IRAK20.32763579
133MAPK90.32630021
134GSK3B0.32162337

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.12482776
2Synaptic vesicle cycle_Homo sapiens_hsa047213.53422784
3GABAergic synapse_Homo sapiens_hsa047272.94552369
4Circadian entrainment_Homo sapiens_hsa047132.83520522
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.78448289
6Glutamatergic synapse_Homo sapiens_hsa047242.72267862
7Olfactory transduction_Homo sapiens_hsa047402.64113580
8Morphine addiction_Homo sapiens_hsa050322.63068551
9Long-term potentiation_Homo sapiens_hsa047202.50947128
10Amphetamine addiction_Homo sapiens_hsa050312.31470836
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.23324964
12Insulin secretion_Homo sapiens_hsa049112.18839613
13Dopaminergic synapse_Homo sapiens_hsa047282.17340976
14Taste transduction_Homo sapiens_hsa047422.14009255
15Salivary secretion_Homo sapiens_hsa049702.01032837
16Cholinergic synapse_Homo sapiens_hsa047251.88000158
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.87485770
18Cocaine addiction_Homo sapiens_hsa050301.76157822
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.75881391
20Gastric acid secretion_Homo sapiens_hsa049711.72462613
21Long-term depression_Homo sapiens_hsa047301.63748030
22Oxytocin signaling pathway_Homo sapiens_hsa049211.63293120
23Phototransduction_Homo sapiens_hsa047441.60680753
24Calcium signaling pathway_Homo sapiens_hsa040201.57351119
25Serotonergic synapse_Homo sapiens_hsa047261.56506346
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.50205803
27Renin secretion_Homo sapiens_hsa049241.47312921
28GnRH signaling pathway_Homo sapiens_hsa049121.41142785
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.40911746
30Huntingtons disease_Homo sapiens_hsa050161.30979897
31Type II diabetes mellitus_Homo sapiens_hsa049301.29887930
32Cardiac muscle contraction_Homo sapiens_hsa042601.28386341
33Gap junction_Homo sapiens_hsa045401.27877654
34Phosphatidylinositol signaling system_Homo sapiens_hsa040701.26904344
35cAMP signaling pathway_Homo sapiens_hsa040241.25079043
36Collecting duct acid secretion_Homo sapiens_hsa049661.22792014
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.21183842
38Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20430230
39Linoleic acid metabolism_Homo sapiens_hsa005911.20263591
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19759981
41Phenylalanine metabolism_Homo sapiens_hsa003601.11254944
42Axon guidance_Homo sapiens_hsa043601.06799926
43Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.05205661
44Histidine metabolism_Homo sapiens_hsa003401.02576533
45alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.01754459
46Estrogen signaling pathway_Homo sapiens_hsa049151.01655783
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.01409633
48Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00151353
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99092828
50Asthma_Homo sapiens_hsa053100.99083946
51ErbB signaling pathway_Homo sapiens_hsa040120.95078888
52cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94850044
53Circadian rhythm_Homo sapiens_hsa047100.94766098
54Pancreatic secretion_Homo sapiens_hsa049720.93580104
55Chemical carcinogenesis_Homo sapiens_hsa052040.91501428
56Oxidative phosphorylation_Homo sapiens_hsa001900.89867306
57Dilated cardiomyopathy_Homo sapiens_hsa054140.87473396
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.86755129
59Notch signaling pathway_Homo sapiens_hsa043300.85886810
60Melanogenesis_Homo sapiens_hsa049160.85530572
61Glioma_Homo sapiens_hsa052140.83554680
62Oocyte meiosis_Homo sapiens_hsa041140.80805504
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80290886
64Vascular smooth muscle contraction_Homo sapiens_hsa042700.78083212
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.77811220
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77563933
67Tyrosine metabolism_Homo sapiens_hsa003500.77075029
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76520194
69beta-Alanine metabolism_Homo sapiens_hsa004100.75320368
70MAPK signaling pathway_Homo sapiens_hsa040100.74950524
71Dorso-ventral axis formation_Homo sapiens_hsa043200.73615560
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73534677
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.72558052
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71157348
75Vibrio cholerae infection_Homo sapiens_hsa051100.70941308
76Thyroid hormone signaling pathway_Homo sapiens_hsa049190.69151747
77Thyroid hormone synthesis_Homo sapiens_hsa049180.68884082
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.68834816
79Nitrogen metabolism_Homo sapiens_hsa009100.68598542
80Alcoholism_Homo sapiens_hsa050340.68023914
81Inositol phosphate metabolism_Homo sapiens_hsa005620.66843888
82Glucagon signaling pathway_Homo sapiens_hsa049220.66533478
83Allograft rejection_Homo sapiens_hsa053300.65491480
84Choline metabolism in cancer_Homo sapiens_hsa052310.65455813
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65070744
86Regulation of autophagy_Homo sapiens_hsa041400.63777560
87Parkinsons disease_Homo sapiens_hsa050120.63490601
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.62859196
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62044868
90Ether lipid metabolism_Homo sapiens_hsa005650.61259275
91ABC transporters_Homo sapiens_hsa020100.59971927
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58930157
93Rheumatoid arthritis_Homo sapiens_hsa053230.58861469
94Steroid biosynthesis_Homo sapiens_hsa001000.58327602
95Autoimmune thyroid disease_Homo sapiens_hsa053200.55052437
96Alzheimers disease_Homo sapiens_hsa050100.54901065
97Phagosome_Homo sapiens_hsa041450.53590134
98Bile secretion_Homo sapiens_hsa049760.52396842
99mTOR signaling pathway_Homo sapiens_hsa041500.50283792
100Endometrial cancer_Homo sapiens_hsa052130.49640239
101Insulin signaling pathway_Homo sapiens_hsa049100.48913674
102VEGF signaling pathway_Homo sapiens_hsa043700.48369777
103Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48286009
104Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.47845913
105Graft-versus-host disease_Homo sapiens_hsa053320.46646633
106Butanoate metabolism_Homo sapiens_hsa006500.46628199
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46245536
108Ras signaling pathway_Homo sapiens_hsa040140.46212835
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46049370
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45867802
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.45613191
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.44100385
113Ovarian steroidogenesis_Homo sapiens_hsa049130.43669205
114Rap1 signaling pathway_Homo sapiens_hsa040150.41390593
115Non-small cell lung cancer_Homo sapiens_hsa052230.41315443
116Type I diabetes mellitus_Homo sapiens_hsa049400.40907004
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40651665
118Peroxisome_Homo sapiens_hsa041460.40453091
119Endocytosis_Homo sapiens_hsa041440.40052585
120Arachidonic acid metabolism_Homo sapiens_hsa005900.39001525
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38076697
122Wnt signaling pathway_Homo sapiens_hsa043100.38064489
123Glycosaminoglycan degradation_Homo sapiens_hsa005310.37580453
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.36907448
125Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36798345
126Renal cell carcinoma_Homo sapiens_hsa052110.36064763
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.35626498
128Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31297263
129Fatty acid biosynthesis_Homo sapiens_hsa000610.29425086
130Colorectal cancer_Homo sapiens_hsa052100.28624286
131Chemokine signaling pathway_Homo sapiens_hsa040620.27754582
132Prion diseases_Homo sapiens_hsa050200.26231406
133Central carbon metabolism in cancer_Homo sapiens_hsa052300.24138561
134Hedgehog signaling pathway_Homo sapiens_hsa043400.23206916
135SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19434996

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »