DEPDC7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of meiosis I (GO:0060631)7.12204026
2DNA methylation involved in gamete generation (GO:0043046)5.25389979
3meiotic cell cycle (GO:0051321)5.18567773
4regulation of female gonad development (GO:2000194)4.88772185
5synapsis (GO:0007129)4.84182006
6centriole replication (GO:0007099)4.83469071
7serine family amino acid catabolic process (GO:0009071)4.82274586
8sulfur amino acid catabolic process (GO:0000098)4.54363909
9glycine metabolic process (GO:0006544)4.44867681
10erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.43170065
11L-phenylalanine metabolic process (GO:0006558)4.43170065
12mitotic metaphase plate congression (GO:0007080)4.42258407
13erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.35153685
14L-phenylalanine catabolic process (GO:0006559)4.35153685
15folic acid metabolic process (GO:0046655)4.33436405
16CENP-A containing nucleosome assembly (GO:0034080)4.20079270
17cysteine metabolic process (GO:0006534)4.18507169
18protein localization to chromosome, centromeric region (GO:0071459)4.09193078
19aromatic amino acid family catabolic process (GO:0009074)4.01831416
20vitamin transmembrane transport (GO:0035461)4.00557529
21gene silencing by RNA (GO:0031047)4.00543452
22proline biosynthetic process (GO:0006561)3.98396987
23serine family amino acid metabolic process (GO:0009069)3.96711165
24chromatin remodeling at centromere (GO:0031055)3.94154150
25transcription from mitochondrial promoter (GO:0006390)3.86044399
26negative regulation of fatty acid biosynthetic process (GO:0045717)3.85122983
27urea cycle (GO:0000050)3.81989332
28urea metabolic process (GO:0019627)3.81989332
29chromosome organization involved in meiosis (GO:0070192)3.81495605
30histone exchange (GO:0043486)3.78801447
31regulation of histone H3-K9 methylation (GO:0051570)3.78497900
32nuclear pore organization (GO:0006999)3.78049902
33indolalkylamine catabolic process (GO:0046218)3.76517948
34tryptophan catabolic process (GO:0006569)3.76517948
35indole-containing compound catabolic process (GO:0042436)3.76517948
36serine family amino acid biosynthetic process (GO:0009070)3.75966856
37proline metabolic process (GO:0006560)3.74991014
38male meiosis (GO:0007140)3.71234708
39glyoxylate metabolic process (GO:0046487)3.70226610
40kynurenine metabolic process (GO:0070189)3.70084835
41oogenesis (GO:0048477)3.70074680
42positive regulation of chromosome segregation (GO:0051984)3.58170122
43regulation of acrosome reaction (GO:0060046)3.57068505
44primitive streak formation (GO:0090009)3.56963963
45male meiosis I (GO:0007141)3.56702962
46retinal cone cell development (GO:0046549)3.54942726
47nitrogen cycle metabolic process (GO:0071941)3.53851586
48triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.52576793
49tryptophan metabolic process (GO:0006568)3.52271442
50binding of sperm to zona pellucida (GO:0007339)3.49604773
51S-adenosylmethionine metabolic process (GO:0046500)3.44650840
52regulation of spindle organization (GO:0090224)3.43172526
53metaphase plate congression (GO:0051310)3.41336030
54replication fork processing (GO:0031297)3.41211737
55purine nucleobase biosynthetic process (GO:0009113)3.38924633
56epoxygenase P450 pathway (GO:0019373)3.38888967
57centriole assembly (GO:0098534)3.37469482
58proteasome assembly (GO:0043248)3.34718564
59nuclear pore complex assembly (GO:0051292)3.34468533
60bile acid biosynthetic process (GO:0006699)3.34112442
61folic acid transport (GO:0015884)3.32467182
62bile acid metabolic process (GO:0008206)3.30957921
63pantothenate metabolic process (GO:0015939)3.30899689
64multicellular organism reproduction (GO:0032504)3.29906706
65meiotic nuclear division (GO:0007126)3.29248759
66aromatic amino acid family metabolic process (GO:0009072)3.29236421
67negative regulation of lipase activity (GO:0060192)3.29225013
68cellular glucuronidation (GO:0052695)3.27452374
69positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.26189167
70positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.26189167
71positive regulation of mitotic sister chromatid separation (GO:1901970)3.26189167
72heme transport (GO:0015886)3.24667733
73DNA replication-independent nucleosome assembly (GO:0006336)3.23530031
74DNA replication-independent nucleosome organization (GO:0034724)3.23530031
75regulation of protein activation cascade (GO:2000257)3.23012782
76maturation of 5.8S rRNA (GO:0000460)3.22793275
77urate metabolic process (GO:0046415)3.22644926
78synaptonemal complex assembly (GO:0007130)3.20692025
79meiotic cell cycle process (GO:1903046)3.19709383
80exogenous drug catabolic process (GO:0042738)3.19314325
81positive regulation of histone H3-K4 methylation (GO:0051571)3.18793088
82sulfur amino acid metabolic process (GO:0000096)3.15494895
83protein K6-linked ubiquitination (GO:0085020)3.14149067
84regulation of meiosis (GO:0040020)3.14114409
85maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.13473178
86homocysteine metabolic process (GO:0050667)3.12799719
87DNA deamination (GO:0045006)3.11770658
88acylglycerol homeostasis (GO:0055090)3.11108243
89triglyceride homeostasis (GO:0070328)3.11108243
90regulation of bile acid biosynthetic process (GO:0070857)3.09322129
91amino-acid betaine metabolic process (GO:0006577)3.08860616
92mitotic sister chromatid segregation (GO:0000070)3.06435032
93regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.06260481
94protein localization to kinetochore (GO:0034501)3.05260831
95DNA replication checkpoint (GO:0000076)3.05194418
96genitalia morphogenesis (GO:0035112)3.05002479
97negative regulation of fibrinolysis (GO:0051918)3.04869637
98regulation of complement activation (GO:0030449)3.02987782
99regulation of sister chromatid cohesion (GO:0007063)3.02602459
100cholesterol efflux (GO:0033344)3.01662600
101DNA replication-dependent nucleosome organization (GO:0034723)3.01560975
102DNA replication-dependent nucleosome assembly (GO:0006335)3.01560975
103one-carbon metabolic process (GO:0006730)3.01301645
104high-density lipoprotein particle remodeling (GO:0034375)3.00604694
105biotin metabolic process (GO:0006768)3.00542250
106protein localization to chromosome (GO:0034502)3.00066838
107piRNA metabolic process (GO:0034587)2.99771180
108oxidative demethylation (GO:0070989)2.99708477
109L-serine metabolic process (GO:0006563)2.97467928
110bile acid and bile salt transport (GO:0015721)2.97453260
111uronic acid metabolic process (GO:0006063)2.96134619
112glucuronate metabolic process (GO:0019585)2.96134619
113attachment of spindle microtubules to kinetochore (GO:0008608)2.95802328
114response to nitrosative stress (GO:0051409)2.94324327
115intestinal epithelial cell development (GO:0060576)2.94083335
116vitamin transport (GO:0051180)2.94005590
117omega-hydroxylase P450 pathway (GO:0097267)2.93359767
118sulfur amino acid biosynthetic process (GO:0000097)2.91385237
119L-methionine salvage (GO:0071267)2.90801099
120L-methionine biosynthetic process (GO:0071265)2.90801099
121amino acid salvage (GO:0043102)2.90801099
122translesion synthesis (GO:0019985)2.89065062
123alpha-amino acid catabolic process (GO:1901606)2.88305164
124meiosis I (GO:0007127)2.87650451
125female gamete generation (GO:0007292)2.87591544
126regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.87550612
127sister chromatid cohesion (GO:0007062)2.87455164
128peptidyl-glutamic acid carboxylation (GO:0017187)2.87098794
129protein carboxylation (GO:0018214)2.87098794
130nucleobase biosynthetic process (GO:0046112)2.87005780
131regulation of cholesterol esterification (GO:0010872)2.86334407
132ribosome assembly (GO:0042255)2.85995016
133sperm-egg recognition (GO:0035036)2.85788649
134very-low-density lipoprotein particle assembly (GO:0034379)2.85312452
135synaptonemal complex organization (GO:0070193)2.84834116
136complement activation, alternative pathway (GO:0006957)2.83725330
137mitochondrial DNA metabolic process (GO:0032042)2.83013373
138cullin deneddylation (GO:0010388)2.82214664
139regulation of double-strand break repair via homologous recombination (GO:0010569)2.81683647
140regulation of cell maturation (GO:1903429)2.81650153
141glutamine family amino acid biosynthetic process (GO:0009084)2.80937290
142base-excision repair, AP site formation (GO:0006285)2.80846440
143regulation of fibrinolysis (GO:0051917)2.80118241
144regulation of centriole replication (GO:0046599)2.79711883
145meiotic chromosome segregation (GO:0045132)2.79462301
146establishment of chromosome localization (GO:0051303)2.79099059
147mitotic chromosome condensation (GO:0007076)2.78946172
148kinetochore assembly (GO:0051382)2.78938369
149drug catabolic process (GO:0042737)2.78841313
150regulation of chromosome segregation (GO:0051983)2.78666597
151regulation of mitotic spindle organization (GO:0060236)2.78435702
152regulation of DNA methylation (GO:0044030)2.78108417
153plasma lipoprotein particle assembly (GO:0034377)2.77983542
154positive regulation of cellular amine metabolic process (GO:0033240)2.77060187
155mitotic G2/M transition checkpoint (GO:0044818)2.76745127
156regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.76050752
157regulation of mitotic metaphase/anaphase transition (GO:0030071)2.76050752
158chromosome condensation (GO:0030261)2.74830485
159fertilization (GO:0009566)2.73847202
160nucleotide-excision repair, DNA gap filling (GO:0006297)2.71778937
161regulation of chromatin silencing (GO:0031935)2.71325901
162oocyte development (GO:0048599)2.69829666
163centrosome duplication (GO:0051298)2.69000365
164regulation of spindle checkpoint (GO:0090231)2.68445752
165negative regulation of reproductive process (GO:2000242)2.65699177
166spindle checkpoint (GO:0031577)2.64327088
167telomere maintenance via semi-conservative replication (GO:0032201)2.63935435

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.13042432
2EZH2_22144423_ChIP-Seq_EOC_Human4.57026481
3RXR_22158963_ChIP-Seq_LIVER_Mouse4.16649170
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.86367821
5PPARA_22158963_ChIP-Seq_LIVER_Mouse3.48546953
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.45610001
7* EGR1_23403033_ChIP-Seq_LIVER_Mouse3.24728650
8E2F7_22180533_ChIP-Seq_HELA_Human3.18836344
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.04431030
10LXR_22158963_ChIP-Seq_LIVER_Mouse2.96383667
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.94549977
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.89022826
13AR_21909140_ChIP-Seq_LNCAP_Human2.82920867
14CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.79929740
15CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.78896446
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.51088052
17MYC_18555785_ChIP-Seq_MESCs_Mouse2.49560384
18NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.30596803
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.27587805
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.25701589
21FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.18846740
22SALL1_21062744_ChIP-ChIP_HESCs_Human2.10203547
23KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.08468857
24E2F4_17652178_ChIP-ChIP_JURKAT_Human1.97836473
25MYC_18358816_ChIP-ChIP_MESCs_Mouse1.94404992
26POU3F2_20337985_ChIP-ChIP_501MEL_Human1.93423903
27POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.91404493
28PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.81118654
29ETS1_20019798_ChIP-Seq_JURKAT_Human1.80488975
30CREB1_15753290_ChIP-ChIP_HEK293T_Human1.80408716
31ZNF263_19887448_ChIP-Seq_K562_Human1.77564595
32MYC_19030024_ChIP-ChIP_MESCs_Mouse1.75902016
33NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74674145
34KAP1_22055183_ChIP-Seq_ESCs_Mouse1.74284733
35NELFA_20434984_ChIP-Seq_ESCs_Mouse1.72347443
36STAT3_1855785_ChIP-Seq_MESCs_Mouse1.72293955
37* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.71849800
38SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.69885380
39MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.69725113
40ZNF274_21170338_ChIP-Seq_K562_Hela1.66807616
41NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.65598523
42* FUS_26573619_Chip-Seq_HEK293_Human1.65360597
43MYC_19079543_ChIP-ChIP_MESCs_Mouse1.65274251
44MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62776598
45GABP_17652178_ChIP-ChIP_JURKAT_Human1.61510547
46CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.57903072
47VDR_22108803_ChIP-Seq_LS180_Human1.56162888
48GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.55889452
49EWS_26573619_Chip-Seq_HEK293_Human1.55865555
50TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.55123121
51HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.54941614
52TCF3_18692474_ChIP-Seq_MEFs_Mouse1.52545468
53CBP_20019798_ChIP-Seq_JUKART_Human1.50832206
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50832206
55UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.50781941
56NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.48805938
57GABP_19822575_ChIP-Seq_HepG2_Human1.48265145
58GBX2_23144817_ChIP-Seq_PC3_Human1.47817998
59TCF3_18692474_ChIP-Seq_MESCs_Mouse1.47648530
60NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.46825881
61P300_19829295_ChIP-Seq_ESCs_Human1.45565220
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.43834107
63PADI4_21655091_ChIP-ChIP_MCF-7_Human1.42949414
64DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.41929921
65AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.40261054
66CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39468438
67EST1_17652178_ChIP-ChIP_JURKAT_Human1.39394693
68* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.39098644
69ELK1_19687146_ChIP-ChIP_HELA_Human1.36022656
70EZH2_27294783_Chip-Seq_NPCs_Mouse1.35832060
71KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.34015528
72KDM5A_27292631_Chip-Seq_BREAST_Human1.34009996
73EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.33252676
74DCP1A_22483619_ChIP-Seq_HELA_Human1.32823229
75E2F1_21310950_ChIP-Seq_MCF-7_Human1.30999295
76PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.29932233
77NANOG_21062744_ChIP-ChIP_HESCs_Human1.29379662
78SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.28576428
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28213423
80HTT_18923047_ChIP-ChIP_STHdh_Human1.27750704
81POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26932379
82PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.26561358
83KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.24181962
84* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.20571824
85TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17814356
86MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.17118933
87KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.16271426
88KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.16271426
89KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.16271426
90SOX2_18692474_ChIP-Seq_MEFs_Mouse1.15570429
91POU5F1_16518401_ChIP-PET_MESCs_Mouse1.14831873
92SOX2_19829295_ChIP-Seq_ESCs_Human1.14666584
93NANOG_19829295_ChIP-Seq_ESCs_Human1.14666584
94* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.14434290
95NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.13045346
96ER_23166858_ChIP-Seq_MCF-7_Human1.12180314
97ZFP57_27257070_Chip-Seq_ESCs_Mouse1.11586473
98TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10980402
99VDR_23849224_ChIP-Seq_CD4+_Human1.10429495
100MYC_18940864_ChIP-ChIP_HL60_Human1.09183629
101SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08237105
102BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.08021762
103SALL4_22934838_ChIP-ChIP_CD34+_Human1.06155591
104SMAD4_21799915_ChIP-Seq_A2780_Human1.05615703
105SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.04773281
106STAT3_23295773_ChIP-Seq_U87_Human1.04729057
107PCGF2_27294783_Chip-Seq_ESCs_Mouse1.04604964
108SOX2_18692474_ChIP-Seq_MESCs_Mouse1.04507178
109NANOG_18692474_ChIP-Seq_MESCs_Mouse1.04493470
110TCF4_23295773_ChIP-Seq_U87_Human1.04367840
111FLI1_27457419_Chip-Seq_LIVER_Mouse1.04332497
112KAP1_27257070_Chip-Seq_ESCs_Mouse1.03441106
113XRN2_22483619_ChIP-Seq_HELA_Human1.03281859
114SALL4_18804426_ChIP-ChIP_XEN_Mouse1.03034551
115ZFX_18555785_ChIP-Seq_MESCs_Mouse1.02700905
116* SMAD4_21741376_ChIP-Seq_EPCs_Human1.02484366
117RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01804182
118HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01747135
119TAF15_26573619_Chip-Seq_HEK293_Human1.01363791
120EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00648479
121GATA1_26923725_Chip-Seq_HPCs_Mouse0.99934360
122SRF_21415370_ChIP-Seq_HL-1_Mouse0.99648566
123* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.98822889
124NANOG_18692474_ChIP-Seq_MEFs_Mouse0.97810273
125NFE2_27457419_Chip-Seq_LIVER_Mouse0.97785059
126NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.97163704
127EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96700898
128SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96695672
129CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96601315
130NOTCH1_21737748_ChIP-Seq_TLL_Human0.96480789
131SUZ12_27294783_Chip-Seq_NPCs_Mouse0.96312962
132SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.96213123
133* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.95946721
134YY1_21170310_ChIP-Seq_MESCs_Mouse0.95304707
135IRF1_19129219_ChIP-ChIP_H3396_Human0.94949253
136GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.94897446
137SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.94718055
138AUTS2_25519132_ChIP-Seq_293T-REX_Human0.94436036
139* FOXM1_26456572_ChIP-Seq_MCF-7_Human0.94166683
140SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.94053439
141PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94043069
142* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93996941
143FOXP3_21729870_ChIP-Seq_TREG_Human0.93428872
144TP63_19390658_ChIP-ChIP_HaCaT_Human0.93377718
145* CDX2_22108803_ChIP-Seq_LS180_Human0.91697698
146OCT4_18692474_ChIP-Seq_MEFs_Mouse0.91659489
147CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91543241
148KLF5_20875108_ChIP-Seq_MESCs_Mouse0.91380562
149ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.91213492
150RARB_24833708_ChIP-Seq_LIVER_Mouse0.90541020
151AR_25329375_ChIP-Seq_VCAP_Human0.90342233
152* CBP_21632823_ChIP-Seq_H3396_Human0.89962778
153TAL1_26923725_Chip-Seq_HPCs_Mouse0.89756541
154* SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.89497412
155* TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.89366397
156BCAT_22108803_ChIP-Seq_LS180_Human0.89014961
157SMAD3_21741376_ChIP-Seq_EPCs_Human0.88950920
158SOX2_18555785_ChIP-Seq_MESCs_Mouse0.87835726
159* RARA_24833708_ChIP-Seq_LIVER_Mouse0.87694376
160EP300_21415370_ChIP-Seq_HL-1_Mouse0.87230463
161CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86150638
162* FOXH1_21741376_ChIP-Seq_EPCs_Human0.86042748
163CRX_20693478_ChIP-Seq_RETINA_Mouse0.85721028
164FOXA1_21572438_ChIP-Seq_LNCaP_Human0.85582123
165PCGF2_27294783_Chip-Seq_NPCs_Mouse0.85539962
166SPI1_26923725_Chip-Seq_HPCs_Mouse0.85455496
167MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.85266389
168OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85080558
169PU.1_20513432_ChIP-Seq_Bcells_Mouse0.85023617
170STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.84839569
171FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.83629985

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis5.29758334
2MP0002139_abnormal_hepatobiliary_system4.98203286
3MP0003718_maternal_effect4.62855354
4MP0005365_abnormal_bile_salt4.59384079
5MP0005085_abnormal_gallbladder_physiolo4.52949331
6MP0008875_abnormal_xenobiotic_pharmacok4.02766683
7MP0009840_abnormal_foam_cell3.70310176
8MP0003806_abnormal_nucleotide_metabolis3.46473055
9MP0003693_abnormal_embryo_hatching3.42545875
10MP0008057_abnormal_DNA_replication2.78258882
11MP0005451_abnormal_body_composition2.76982492
12MP0003950_abnormal_plasma_membrane2.62650122
13MP0008789_abnormal_olfactory_epithelium2.53049284
14MP0003111_abnormal_nucleus_morphology2.52736589
15MP0010094_abnormal_chromosome_stability2.51473916
16MP0005410_abnormal_fertilization2.41492511
17MP0004957_abnormal_blastocyst_morpholog2.21609396
18MP0005395_other_phenotype2.17231945
19MP0003252_abnormal_bile_duct2.14310588
20MP0010329_abnormal_lipoprotein_level2.10452356
21MP0005332_abnormal_amino_acid2.02782213
22MP0004019_abnormal_vitamin_homeostasis2.02331580
23MP0003077_abnormal_cell_cycle1.95548300
24MP0005394_taste/olfaction_phenotype1.88732310
25MP0005499_abnormal_olfactory_system1.88732310
26MP0002234_abnormal_pharynx_morphology1.86690381
27MP0004264_abnormal_extraembryonic_tissu1.57149388
28MP0000609_abnormal_liver_physiology1.56229416
29MP0003699_abnormal_female_reproductive1.54149085
30MP0001666_abnormal_nutrient_absorption1.52274799
31MP0008058_abnormal_DNA_repair1.47368461
32MP0008932_abnormal_embryonic_tissue1.45857398
33MP0003941_abnormal_skin_development1.44690616
34MP0003186_abnormal_redox_activity1.44234595
35MP0003195_calcinosis1.43005004
36MP0008877_abnormal_DNA_methylation1.41892065
37MP0008260_abnormal_autophagy1.41423958
38MP0001119_abnormal_female_reproductive1.38161301
39MP0003191_abnormal_cellular_cholesterol1.37652373
40MP0003698_abnormal_male_reproductive1.36554037
41MP0010030_abnormal_orbit_morphology1.31909942
42MP0010234_abnormal_vibrissa_follicle1.31628277
43MP0002653_abnormal_ependyma_morphology1.30966601
44MP0003453_abnormal_keratinocyte_physiol1.30956782
45MP0001764_abnormal_homeostasis1.30200255
46MP0002160_abnormal_reproductive_system1.29878973
47MP0003656_abnormal_erythrocyte_physiolo1.28987062
48MP0001730_embryonic_growth_arrest1.26719330
49MP0010368_abnormal_lymphatic_system1.26040947
50MP0003786_premature_aging1.26004106
51MP0005319_abnormal_enzyme/_coenzyme1.23787154
52MP0002233_abnormal_nose_morphology1.19976546
53MP0002118_abnormal_lipid_homeostasis1.19680807
54MP0000579_abnormal_nail_morphology1.17727504
55MP0005083_abnormal_biliary_tract1.15546364
56MP0000653_abnormal_sex_gland1.14054601
57MP0001672_abnormal_embryogenesis/_devel1.13704489
58MP0005380_embryogenesis_phenotype1.13704489
59MP0005647_abnormal_sex_gland1.10709757
60MP0000350_abnormal_cell_proliferation1.09238472
61MP0001929_abnormal_gametogenesis1.08516152
62MP0002210_abnormal_sex_determination1.05166880
63MP0000762_abnormal_tongue_morphology1.02089220
64MP0003890_abnormal_embryonic-extraembry1.00508670
65MP0001697_abnormal_embryo_size0.99136028
66MP0005187_abnormal_penis_morphology0.96858726
67MP0000598_abnormal_liver_morphology0.94961846
68MP0005408_hypopigmentation0.93817322
69MP0003705_abnormal_hypodermis_morpholog0.89957326
70MP0002085_abnormal_embryonic_tissue0.89587520
71MP0002086_abnormal_extraembryonic_tissu0.89014233
72MP0001145_abnormal_male_reproductive0.87251527
73MP0000372_irregular_coat_pigmentation0.83810037
74MP0009697_abnormal_copulation0.83640541
75MP0003879_abnormal_hair_cell0.82145308
76MP0010307_abnormal_tumor_latency0.81950800
77MP0001545_abnormal_hematopoietic_system0.80874431
78MP0005397_hematopoietic_system_phenotyp0.80874431
79MP0005266_abnormal_metabolism0.80312029
80MP0002138_abnormal_hepatobiliary_system0.79817064
81MP0002019_abnormal_tumor_incidence0.79769042
82MP0003984_embryonic_growth_retardation0.79319927
83MP0002161_abnormal_fertility/fecundity0.78622241
84MP0009278_abnormal_bone_marrow0.77088442
85MP0002088_abnormal_embryonic_growth/wei0.77002183
86MP0002084_abnormal_developmental_patter0.76453723
87MP0004084_abnormal_cardiac_muscle0.75905809
88MP0003183_abnormal_peptide_metabolism0.73982266
89MP0003868_abnormal_feces_composition0.73764048
90MP0008995_early_reproductive_senescence0.73297717
91MP0000639_abnormal_adrenal_gland0.73204804
92MP0006292_abnormal_olfactory_placode0.72638132
93MP0002080_prenatal_lethality0.72596937
94MP0009053_abnormal_anal_canal0.70736310
95MP0001324_abnormal_eye_pigmentation0.70593208
96MP0005197_abnormal_uvea_morphology0.70349282
97MP0008007_abnormal_cellular_replicative0.70012694
98MP0003119_abnormal_digestive_system0.69279968
99MP0001984_abnormal_olfaction0.67089344
100MP0009643_abnormal_urine_homeostasis0.67085073
101MP0002249_abnormal_larynx_morphology0.65256648
102MP0005376_homeostasis/metabolism_phenot0.64460114
103MP0002090_abnormal_vision0.63658056
104MP0003755_abnormal_palate_morphology0.61412874
105MP0002269_muscular_atrophy0.61206400
106MP0003646_muscle_fatigue0.60765534
107MP0001915_intracranial_hemorrhage0.60330728
108MP0002102_abnormal_ear_morphology0.60284566
109MP0002132_abnormal_respiratory_system0.58631478
110MP0000490_abnormal_crypts_of0.57870956
111MP0005551_abnormal_eye_electrophysiolog0.57278921
112MP0005058_abnormal_lysosome_morphology0.56251007
113MP0001919_abnormal_reproductive_system0.56186677
114MP0005389_reproductive_system_phenotype0.55844788
115MP0009115_abnormal_fat_cell0.55602449
116MP0000462_abnormal_digestive_system0.55386807
117MP0001293_anophthalmia0.55348918
118MP0009250_abnormal_appendicular_skeleto0.55178251
119MP0010352_gastrointestinal_tract_polyps0.54689622
120MP0003567_abnormal_fetal_cardiomyocyte0.54592667
121MP0002796_impaired_skin_barrier0.54359560
122MP0005220_abnormal_exocrine_pancreas0.53992859
123MP0005023_abnormal_wound_healing0.53767129
124MP0003937_abnormal_limbs/digits/tail_de0.53032555
125MP0000678_abnormal_parathyroid_gland0.52934110
126MP0001986_abnormal_taste_sensitivity0.52874294
127MP0001881_abnormal_mammary_gland0.52276582
128MP0006138_congestive_heart_failure0.52086415
129MP0001661_extended_life_span0.51623837
130MP0009763_increased_sensitivity_to0.51153852
131MP0000627_abnormal_mammary_gland0.51046435
132MP0003935_abnormal_craniofacial_develop0.50337696
133MP0001286_abnormal_eye_development0.50171284
134MP0000427_abnormal_hair_cycle0.47125364
135MP0003136_yellow_coat_color0.46841069
136MP0004142_abnormal_muscle_tone0.46492509
137MP0000049_abnormal_middle_ear0.45828438
138MP0008775_abnormal_heart_ventricle0.44202433
139MP0002751_abnormal_autonomic_nervous0.43742280

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)5.33040446
2Hyperglycinemia (HP:0002154)5.12362264
3Hypobetalipoproteinemia (HP:0003563)4.92001885
4Abnormality of aromatic amino acid family metabolism (HP:0004338)4.89691402
5Intrahepatic cholestasis (HP:0001406)4.87470980
6Abnormality of monocarboxylic acid metabolism (HP:0010996)4.74260067
7Hyperglycinuria (HP:0003108)4.68513471
8Supernumerary spleens (HP:0009799)4.63823882
9Male infertility (HP:0003251)4.28139813
10Osteomalacia (HP:0002749)4.25250468
11Abnormality of serine family amino acid metabolism (HP:0010894)4.16364822
12Abnormality of glycine metabolism (HP:0010895)4.16364822
13Xanthomatosis (HP:0000991)4.07759398
14Breast hypoplasia (HP:0003187)4.02359968
15Cholecystitis (HP:0001082)3.70854842
16Abnormal gallbladder physiology (HP:0012438)3.70854842
17Hypolipoproteinemia (HP:0010981)3.63275401
18Birth length less than 3rd percentile (HP:0003561)3.63151979
19Facial hemangioma (HP:0000329)3.51224976
20Prolonged partial thromboplastin time (HP:0003645)3.50176717
21Hypophosphatemic rickets (HP:0004912)3.48726711
22Hyperlipoproteinemia (HP:0010980)3.44270367
23Gonadotropin excess (HP:0000837)3.42271928
24Hypochromic microcytic anemia (HP:0004840)3.39875275
25Abnormality of serum amino acid levels (HP:0003112)3.38202487
26Impulsivity (HP:0100710)3.37344740
27Oligodactyly (hands) (HP:0001180)3.37293380
28Hyperammonemia (HP:0001987)3.36838100
29Pustule (HP:0200039)3.36077000
30Abnormality of sulfur amino acid metabolism (HP:0004339)3.34252492
31Gout (HP:0001997)3.33286774
32Generalized aminoaciduria (HP:0002909)3.30245372
33Abnormality of pyrimidine metabolism (HP:0004353)3.29970359
34Popliteal pterygium (HP:0009756)3.29671215
35Alopecia of scalp (HP:0002293)3.25279505
36Fat malabsorption (HP:0002630)3.21406847
37Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.13793282
38Complement deficiency (HP:0004431)3.11897536
39Abnormality of methionine metabolism (HP:0010901)3.11564217
40Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.00138095
41Abnormality of aspartate family amino acid metabolism (HP:0010899)2.99380590
42Malnutrition (HP:0004395)2.98216298
43Patellar aplasia (HP:0006443)2.96525843
44Hypoalphalipoproteinemia (HP:0003233)2.94281781
45Premature ovarian failure (HP:0008209)2.90414325
46Aplasia/Hypoplasia of the patella (HP:0006498)2.86773289
47Short tibia (HP:0005736)2.84942562
48Absent septum pellucidum (HP:0001331)2.81150674
49Abnormality of the labia minora (HP:0012880)2.80925159
50Myocardial infarction (HP:0001658)2.79810448
51Proximal tubulopathy (HP:0000114)2.77691811
52Abnormality of chromosome stability (HP:0003220)2.76524197
53Median cleft lip (HP:0000161)2.75110555
54Steatorrhea (HP:0002570)2.69182085
55Abdominal situs inversus (HP:0003363)2.68097324
56Abnormality of abdominal situs (HP:0011620)2.68097324
57Azoospermia (HP:0000027)2.67829930
58Aplasia/Hypoplasia of the uvula (HP:0010293)2.66288249
59Capillary hemangiomas (HP:0005306)2.64216914
60Abnormal biliary tract physiology (HP:0012439)2.64084109
61Bile duct proliferation (HP:0001408)2.64084109
62Abnormality of nucleobase metabolism (HP:0010932)2.62277946
63Chronic hepatic failure (HP:0100626)2.60575185
64Absent radius (HP:0003974)2.59575024
65Meckel diverticulum (HP:0002245)2.58908709
66Fair hair (HP:0002286)2.58425672
67Abnormality of glutamine family amino acid metabolism (HP:0010902)2.58155734
68Epidermoid cyst (HP:0200040)2.55712689
69Abnormality of lateral ventricle (HP:0030047)2.55379653
70Abnormality of the preputium (HP:0100587)2.54270650
71Aplasia/Hypoplasia of the tibia (HP:0005772)2.53791419
72Aplasia/Hypoplasia involving the musculature (HP:0001460)2.51283881
73Polycythemia (HP:0001901)2.46791504
74Lip pit (HP:0100267)2.42125770
75Absent forearm bone (HP:0003953)2.40833805
76Aplasia involving forearm bones (HP:0009822)2.40833805
77Abnormality of the ileum (HP:0001549)2.40795271
78Abnormality of the septum pellucidum (HP:0007375)2.40463136
79Septo-optic dysplasia (HP:0100842)2.40408101
80Lethargy (HP:0001254)2.37915759
81Stillbirth (HP:0003826)2.34891365
82Aplasia/Hypoplasia of the fovea (HP:0008060)2.33979750
83Hypoplasia of the fovea (HP:0007750)2.33979750
84Abnormality of complement system (HP:0005339)2.33709602
85Aplasia of the musculature (HP:0100854)2.32474065
86Carpal bone hypoplasia (HP:0001498)2.32256923
87Joint hemorrhage (HP:0005261)2.31973526
88Abnormality of purine metabolism (HP:0004352)2.28431740
89Secondary amenorrhea (HP:0000869)2.28414961
90Small intestinal stenosis (HP:0012848)2.27964607
91Duodenal stenosis (HP:0100867)2.27964607
92Cortical dysplasia (HP:0002539)2.26919615
93Abnormal spermatogenesis (HP:0008669)2.25828970
94Spontaneous abortion (HP:0005268)2.25425634
95Irritability (HP:0000737)2.25218754
96Rickets (HP:0002748)2.24654914
97Abnormal tarsal ossification (HP:0008369)2.24409269
98Ketosis (HP:0001946)2.23421304
99Abnormality of the common coagulation pathway (HP:0010990)2.21803769
100Megaloblastic anemia (HP:0001889)2.20335528
101Abnormal lung lobation (HP:0002101)2.15561272
102Hypercholesterolemia (HP:0003124)2.13563923
103Cerebral hypomyelination (HP:0006808)2.12189580
104Increased purine levels (HP:0004368)2.11617142
105Hyperuricemia (HP:0002149)2.11617142
106Glycosuria (HP:0003076)2.11388532
107Abnormality of urine glucose concentration (HP:0011016)2.11388532
108Hyperglycemia (HP:0003074)2.11160130
109Abnormality of the duodenum (HP:0002246)2.09878346
110Papillary thyroid carcinoma (HP:0002895)2.08970817
111Abnormality of the intrinsic pathway (HP:0010989)2.04094830
112Bifid tongue (HP:0010297)2.02548022
113Oligodactyly (HP:0012165)2.02422587
114Abnormality of fatty-acid metabolism (HP:0004359)2.02022306
115Wrist flexion contracture (HP:0001239)2.01102855
116Posterior subcapsular cataract (HP:0007787)2.00067867
117Nausea (HP:0002018)1.99796561
118Abnormality of the fovea (HP:0000493)1.98008553
119Abnormality of male internal genitalia (HP:0000022)1.96775711
120Shawl scrotum (HP:0000049)1.96413379
121Abnormality of the vitamin B12 metabolism (HP:0004341)1.95083583
122Increased serum pyruvate (HP:0003542)1.95026399
123Rib fusion (HP:0000902)1.94878980
124Turricephaly (HP:0000262)1.93167011
125Amniotic constriction ring (HP:0009775)1.88902302
126Abnormality of placental membranes (HP:0011409)1.88902302
127Vaginal fistula (HP:0004320)1.88840909
128Prolonged neonatal jaundice (HP:0006579)1.88578859
129Ankle contracture (HP:0006466)1.87927796
130Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.87396450
131Subcapsular cataract (HP:0000523)1.86569216
132Abnormality of carpal bone ossification (HP:0006257)1.85171500
133Horseshoe kidney (HP:0000085)1.84437225
134Metaphyseal irregularity (HP:0003025)1.82296042
135Type 2 muscle fiber atrophy (HP:0003554)1.82267998
136Aplasia/hypoplasia of the humerus (HP:0006507)1.81364951
137Ureteral duplication (HP:0000073)1.80716859
138Spastic diplegia (HP:0001264)1.80247852
139Dysautonomia (HP:0002459)1.79580548
140Hepatocellular carcinoma (HP:0001402)1.78853488
141Squamous cell carcinoma (HP:0002860)1.78683447
142Elevated alkaline phosphatase (HP:0003155)1.78182273
143Abnormal auditory evoked potentials (HP:0006958)1.76672423
144Oral leukoplakia (HP:0002745)1.75951823
145Conjugated hyperbilirubinemia (HP:0002908)1.75889150
146Hypoglycemic coma (HP:0001325)1.75779813
147Death in infancy (HP:0001522)1.75619451
148Tongue fasciculations (HP:0001308)1.75379364
149Breast aplasia (HP:0100783)1.73218102
150Rhabdomyosarcoma (HP:0002859)1.72063501
151Short humerus (HP:0005792)1.71388821
152Chromsome breakage (HP:0040012)1.71289315
153Infertility (HP:0000789)1.70844667
154Confusion (HP:0001289)1.67853627
155Ulnar bowing (HP:0003031)1.67669461
156Brushfield spots (HP:0001088)1.67534944
157Chromosomal breakage induced by crosslinking agents (HP:0003221)1.67062069
158Adrenal hypoplasia (HP:0000835)1.66416402
159Rough bone trabeculation (HP:0100670)1.65970363

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.19865341
2MAP3K64.06084749
3LATS23.15886277
4TRIM283.10082640
5PLK42.90411215
6LATS12.89186826
7PINK12.88056202
8TAOK32.88016402
9TTK2.82508712
10STK38L2.71025657
11BMPR22.52243966
12MOS2.43790604
13WEE12.43313471
14NEK62.22956023
15AKT32.20176132
16PLK11.99565866
17MET1.99560633
18NEK21.95862220
19BCKDK1.87914007
20MAPK151.87234504
21EPHA21.83622743
22MAP3K111.82387381
23ICK1.77423829
24CHEK21.75351517
25STK391.72351747
26SRPK11.66888572
27DDR21.64710762
28ACVR1B1.62467503
29STK31.58792138
30EIF2AK11.58181732
31CDC71.57045258
32ERBB41.56983498
33STK241.56822708
34BRAF1.56716028
35PNCK1.55823603
36MUSK1.53036425
37MST41.47290005
38BRSK21.46128869
39CDK71.42359048
40NEK11.38022236
41TNIK1.33767787
42PIK3CG1.32809618
43CSNK1G11.31995566
44BMPR1B1.31255135
45KSR11.28503364
46NUAK11.18490574
47AURKB1.17903413
48ARAF1.16627395
49TYRO31.15534452
50CDK61.15282651
51DYRK21.12737016
52STK101.12673420
53AURKA1.12195912
54MELK1.12056173
55ERBB31.10231856
56DYRK31.09553558
57PIM11.07543485
58FGR1.05097107
59BRD41.03297573
60TAOK11.03020213
61MAP3K81.02130444
62CDK41.00640734
63MAPK110.99737639
64PLK20.96291666
65MAP3K40.95014261
66STK160.94748930
67NEK90.94384283
68OXSR10.90110112
69PLK30.89427425
70CSNK1G30.89267764
71MAP3K90.89159490
72RPS6KA40.88371037
73PRKD20.87465127
74BCR0.87424282
75PRKAA10.85843636
76PIM20.85679820
77RAF10.84275683
78TSSK60.83839988
79WNK30.83774858
80ABL20.82086366
81MATK0.80872273
82TAOK20.79910642
83TESK20.78956742
84TGFBR10.73424766
85CSNK1A1L0.73239045
86MAP4K20.71278308
87CDK80.70846593
88CCNB10.70349922
89MST1R0.70204327
90VRK10.64355693
91BMX0.63768872
92BRSK10.62675696
93CHEK10.61297128
94STK380.61148315
95DYRK1B0.60883824
96INSRR0.59929560
97CDK190.59715204
98CDK120.59267855
99ZAK0.58508091
100CSNK1G20.57343265
101ATR0.56687440
102NME10.55879549
103CDK20.55620097
104CSK0.55093862
105KSR20.54909179
106MAP3K50.54234838
107PRKAA20.54005645
108SIK30.52623470
109MTOR0.51485968
110MKNK20.50183344
111STK40.50180756
112PDK20.49925339
113MAP3K120.49699531
114EIF2AK30.48947614
115GSK3A0.48913926
116PRKCI0.47417476
117WNK40.46769370
118DMPK0.45751701
119RPS6KB20.45455861
120MAPKAPK50.45339580
121PRKG10.44345089
122ILK0.44255483
123FGFR40.43805069
124ATM0.42227836
125PKN10.41599457
126CSNK1D0.40150631
127MAPK130.39445721
128PRKACB0.39216367
129PRKD30.38262673
130PAK10.38213543
131CDK10.37897364
132MAP3K30.37630297
133CSNK2A20.36493514
134CSNK2A10.36255035
135PDK30.34341448
136PDK40.34341448
137CDK90.34327013
138CSNK1E0.33480338
139PBK0.32126456
140MAP2K20.29965238
141MAP3K130.29333999
142CAMK2G0.28867812
143MKNK10.27508097
144MAPK10.24137263
145ABL10.24049778

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.64942569
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.24323913
3Primary bile acid biosynthesis_Homo sapiens_hsa001203.05122975
4Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.79157142
5Pentose and glucuronate interconversions_Homo sapiens_hsa000402.72871737
6Folate biosynthesis_Homo sapiens_hsa007902.52684503
7Arginine biosynthesis_Homo sapiens_hsa002202.34012876
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.29272891
9Drug metabolism - other enzymes_Homo sapiens_hsa009832.11797707
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.99791512
11Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.99658870
12Nitrogen metabolism_Homo sapiens_hsa009101.91649188
13Cysteine and methionine metabolism_Homo sapiens_hsa002701.88302452
14Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.83433580
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.80466780
16Complement and coagulation cascades_Homo sapiens_hsa046101.77048732
17Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.73831415
18Steroid hormone biosynthesis_Homo sapiens_hsa001401.67382757
19Chemical carcinogenesis_Homo sapiens_hsa052041.65398302
20Tryptophan metabolism_Homo sapiens_hsa003801.64244927
21Retinol metabolism_Homo sapiens_hsa008301.63282286
22Biosynthesis of amino acids_Homo sapiens_hsa012301.58266339
23Selenocompound metabolism_Homo sapiens_hsa004501.54797406
24Butanoate metabolism_Homo sapiens_hsa006501.54412309
25Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.53963036
26Base excision repair_Homo sapiens_hsa034101.53760438
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.49868884
28Arginine and proline metabolism_Homo sapiens_hsa003301.45058377
29RNA polymerase_Homo sapiens_hsa030201.44696940
30Mismatch repair_Homo sapiens_hsa034301.43213627
31Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.41046191
32Cell cycle_Homo sapiens_hsa041101.40196847
33Fatty acid degradation_Homo sapiens_hsa000711.39748584
34RNA transport_Homo sapiens_hsa030131.37991550
35Peroxisome_Homo sapiens_hsa041461.37782531
36Vitamin digestion and absorption_Homo sapiens_hsa049771.32143725
37DNA replication_Homo sapiens_hsa030301.32028028
38Fatty acid metabolism_Homo sapiens_hsa012121.31697194
39Sulfur relay system_Homo sapiens_hsa041221.30352410
40Fatty acid biosynthesis_Homo sapiens_hsa000611.29074314
41Histidine metabolism_Homo sapiens_hsa003401.28621432
42One carbon pool by folate_Homo sapiens_hsa006701.26423504
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.25874417
44beta-Alanine metabolism_Homo sapiens_hsa004101.23107248
45Steroid biosynthesis_Homo sapiens_hsa001001.22743742
46Non-homologous end-joining_Homo sapiens_hsa034501.22734537
47Basal transcription factors_Homo sapiens_hsa030221.19911671
48Glutathione metabolism_Homo sapiens_hsa004801.17539505
49Circadian rhythm_Homo sapiens_hsa047101.13992967
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.06304684
51Propanoate metabolism_Homo sapiens_hsa006401.05717962
52p53 signaling pathway_Homo sapiens_hsa041151.05008836
53PPAR signaling pathway_Homo sapiens_hsa033201.04295545
54Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01579877
55Staphylococcus aureus infection_Homo sapiens_hsa051501.00110594
56Caffeine metabolism_Homo sapiens_hsa002320.96568511
57Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.96248467
58Starch and sucrose metabolism_Homo sapiens_hsa005000.95302739
59Homologous recombination_Homo sapiens_hsa034400.94718265
60Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.93117711
61Nucleotide excision repair_Homo sapiens_hsa034200.92048705
62Pentose phosphate pathway_Homo sapiens_hsa000300.90940175
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90916935
64Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.89007257
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87712224
66Maturity onset diabetes of the young_Homo sapiens_hsa049500.85928412
67Pyrimidine metabolism_Homo sapiens_hsa002400.85813344
68Fat digestion and absorption_Homo sapiens_hsa049750.84774700
69Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84726259
70Proteasome_Homo sapiens_hsa030500.83876908
71Protein export_Homo sapiens_hsa030600.83229694
72Linoleic acid metabolism_Homo sapiens_hsa005910.81552276
73Fanconi anemia pathway_Homo sapiens_hsa034600.80964256
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.80004822
75Tyrosine metabolism_Homo sapiens_hsa003500.79303033
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.78739414
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.77662931
78Regulation of autophagy_Homo sapiens_hsa041400.76216883
79Carbon metabolism_Homo sapiens_hsa012000.76019642
80Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.74390484
81Bile secretion_Homo sapiens_hsa049760.72935199
82Pyruvate metabolism_Homo sapiens_hsa006200.72643344
83Phenylalanine metabolism_Homo sapiens_hsa003600.68740642
84RNA degradation_Homo sapiens_hsa030180.63158164
85Glycerolipid metabolism_Homo sapiens_hsa005610.62099989
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.58951722
87Fatty acid elongation_Homo sapiens_hsa000620.58845841
88Oocyte meiosis_Homo sapiens_hsa041140.56446469
89Lysine degradation_Homo sapiens_hsa003100.56121891
90ABC transporters_Homo sapiens_hsa020100.55572379
91Arachidonic acid metabolism_Homo sapiens_hsa005900.54402519
92Sulfur metabolism_Homo sapiens_hsa009200.53588247
93Metabolic pathways_Homo sapiens_hsa011000.53261778
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.50947727
95Fructose and mannose metabolism_Homo sapiens_hsa000510.50922944
96Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.49686892
97Olfactory transduction_Homo sapiens_hsa047400.48768052
98Spliceosome_Homo sapiens_hsa030400.48257005
99mRNA surveillance pathway_Homo sapiens_hsa030150.46757796
100Renin-angiotensin system_Homo sapiens_hsa046140.45143572
101Dorso-ventral axis formation_Homo sapiens_hsa043200.40146666
102Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38981460
103Ovarian steroidogenesis_Homo sapiens_hsa049130.38672522
104Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34249475
105Purine metabolism_Homo sapiens_hsa002300.32863596
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30432768
107TGF-beta signaling pathway_Homo sapiens_hsa043500.28545589
108mTOR signaling pathway_Homo sapiens_hsa041500.25077198
109Galactose metabolism_Homo sapiens_hsa000520.25000502
110Protein digestion and absorption_Homo sapiens_hsa049740.22063388
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.20685542
112Hippo signaling pathway_Homo sapiens_hsa043900.20253739
113Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.12495014

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