

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | telomere maintenance via semi-conservative replication (GO:0032201) | 6.41629608 |
| 2 | DNA strand elongation involved in DNA replication (GO:0006271) | 6.39245366 |
| 3 | DNA strand elongation (GO:0022616) | 6.13944509 |
| 4 | CENP-A containing nucleosome assembly (GO:0034080) | 6.02084636 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 5.79721329 |
| 6 | telomere maintenance via recombination (GO:0000722) | 5.60814510 |
| 7 | mitotic recombination (GO:0006312) | 5.42087979 |
| 8 | mitotic chromosome condensation (GO:0007076) | 5.26035449 |
| 9 | DNA unwinding involved in DNA replication (GO:0006268) | 5.24425277 |
| 10 | DNA replication initiation (GO:0006270) | 4.94372752 |
| 11 | DNA replication checkpoint (GO:0000076) | 4.89623677 |
| 12 | mitotic metaphase plate congression (GO:0007080) | 4.78372579 |
| 13 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 4.76088947 |
| 14 | histone exchange (GO:0043486) | 4.75394846 |
| 15 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.70415174 |
| 16 | DNA replication-independent nucleosome organization (GO:0034724) | 4.70415174 |
| 17 | mitotic sister chromatid segregation (GO:0000070) | 4.65226884 |
| 18 | telomere maintenance via telomere lengthening (GO:0010833) | 4.41730146 |
| 19 | protein localization to kinetochore (GO:0034501) | 4.39726889 |
| 20 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.32021378 |
| 21 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.32021378 |
| 22 | deoxyribonucleotide biosynthetic process (GO:0009263) | 4.31616048 |
| 23 | sister chromatid segregation (GO:0000819) | 4.30124276 |
| 24 | protein localization to chromosome, centromeric region (GO:0071459) | 4.27035696 |
| 25 | proteasome assembly (GO:0043248) | 4.25886119 |
| 26 | establishment of integrated proviral latency (GO:0075713) | 4.19295785 |
| 27 | DNA ligation (GO:0006266) | 4.14504004 |
| 28 | mitotic sister chromatid cohesion (GO:0007064) | 4.14267002 |
| 29 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 4.07901185 |
| 30 | metaphase plate congression (GO:0051310) | 4.07470945 |
| 31 | purine nucleobase biosynthetic process (GO:0009113) | 4.03829535 |
| 32 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.96232898 |
| 33 | IMP biosynthetic process (GO:0006188) | 3.93779954 |
| 34 | kinetochore organization (GO:0051383) | 3.92837834 |
| 35 | regulation of centriole replication (GO:0046599) | 3.91975024 |
| 36 | nuclear pore complex assembly (GO:0051292) | 3.86538416 |
| 37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.80365156 |
| 38 | mitotic nuclear envelope disassembly (GO:0007077) | 3.77077901 |
| 39 | nucleobase biosynthetic process (GO:0046112) | 3.72656086 |
| 40 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.72512653 |
| 41 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.72305902 |
| 42 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.71143300 |
| 43 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.68615393 |
| 44 | chromatin assembly or disassembly (GO:0006333) | 3.66631964 |
| 45 | establishment of chromosome localization (GO:0051303) | 3.65051496 |
| 46 | non-recombinational repair (GO:0000726) | 3.61507299 |
| 47 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.61507299 |
| 48 | DNA topological change (GO:0006265) | 3.61335640 |
| 49 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.56105693 |
| 50 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.56105693 |
| 51 | nuclear pore organization (GO:0006999) | 3.53848520 |
| 52 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.53621839 |
| 53 | cell cycle G1/S phase transition (GO:0044843) | 3.53621839 |
| 54 | regulation of sister chromatid cohesion (GO:0007063) | 3.52767385 |
| 55 | establishment of viral latency (GO:0019043) | 3.51198418 |
| 56 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.50806911 |
| 57 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.50806911 |
| 58 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.50676205 |
| 59 | telomere maintenance (GO:0000723) | 3.48785199 |
| 60 | nuclear envelope disassembly (GO:0051081) | 3.47974469 |
| 61 | membrane disassembly (GO:0030397) | 3.47974469 |
| 62 | telomere organization (GO:0032200) | 3.46846357 |
| 63 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.46054973 |
| 64 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.45596994 |
| 65 | DNA double-strand break processing (GO:0000729) | 3.43819864 |
| 66 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.43321045 |
| 67 | negative regulation of ligase activity (GO:0051352) | 3.43321045 |
| 68 | IMP metabolic process (GO:0046040) | 3.35561178 |
| 69 | regulation of chromosome segregation (GO:0051983) | 3.35559089 |
| 70 | chromosome segregation (GO:0007059) | 3.33465740 |
| 71 | ATP-dependent chromatin remodeling (GO:0043044) | 3.33168331 |
| 72 | ribosome assembly (GO:0042255) | 3.32904951 |
| 73 | protein K6-linked ubiquitination (GO:0085020) | 3.31376950 |
| 74 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.30788863 |
| 75 | formation of translation preinitiation complex (GO:0001731) | 3.28884848 |
| 76 | kinetochore assembly (GO:0051382) | 3.28878897 |
| 77 | spindle checkpoint (GO:0031577) | 3.28263924 |
| 78 | chromosome condensation (GO:0030261) | 3.27028309 |
| 79 | negative regulation of chromosome segregation (GO:0051985) | 3.26260809 |
| 80 | positive regulation of chromosome segregation (GO:0051984) | 3.24732796 |
| 81 | base-excision repair (GO:0006284) | 3.23062546 |
| 82 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.22796832 |
| 83 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.19489902 |
| 84 | negative regulation of sister chromatid segregation (GO:0033046) | 3.19489902 |
| 85 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.19489902 |
| 86 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.19489902 |
| 87 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.19489902 |
| 88 | mitotic cell cycle (GO:0000278) | 3.18019565 |
| 89 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.17715092 |
| 90 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.17715092 |
| 91 | mitotic spindle checkpoint (GO:0071174) | 3.16707406 |
| 92 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.14558258 |
| 93 | protein localization to chromosome (GO:0034502) | 3.11198737 |
| 94 | mitotic spindle assembly checkpoint (GO:0007094) | 3.10253878 |
| 95 | spindle assembly checkpoint (GO:0071173) | 3.09652504 |
| 96 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.08524872 |
| 97 | postreplication repair (GO:0006301) | 3.07552379 |
| 98 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.06926565 |
| 99 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.03743117 |
| 100 | regulation of sister chromatid segregation (GO:0033045) | 3.03743117 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.88074564 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.17078105 |
| 3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.11422779 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.92558290 |
| 5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.69012986 |
| 6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.43606601 |
| 7 | AR_21909140_ChIP-Seq_LNCAP_Human | 3.20958132 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.91576470 |
| 9 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.85941546 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.84978129 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.72375829 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.70497985 |
| 13 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.70346951 |
| 14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.68735642 |
| 15 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.60813567 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.45322596 |
| 17 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.43174706 |
| 18 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.37353125 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.34053220 |
| 20 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.34000589 |
| 21 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.30735392 |
| 22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.24877897 |
| 23 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.07668788 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.06172326 |
| 25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.02462939 |
| 26 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.01419974 |
| 27 | E2F7_22180533_ChIP-Seq_HELA_Human | 11.0203907 |
| 28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.99999161 |
| 29 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.98427006 |
| 30 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.98277176 |
| 31 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.94621734 |
| 32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.94088492 |
| 33 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.90183874 |
| 34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.86560103 |
| 35 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.86461791 |
| 36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.76752303 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.76326409 |
| 38 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.74910025 |
| 39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.73225685 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.72476386 |
| 41 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.72285458 |
| 42 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.70281441 |
| 43 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.59136069 |
| 44 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.58547738 |
| 45 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.57394559 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.57107650 |
| 47 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.52623364 |
| 48 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.51348279 |
| 49 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.45638623 |
| 50 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.44196378 |
| 51 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.40398887 |
| 52 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.36462054 |
| 53 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.32463967 |
| 54 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.30707652 |
| 55 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.26750800 |
| 56 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.26018436 |
| 57 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.25445575 |
| 58 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.19321203 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18734854 |
| 60 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.18502964 |
| 61 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.17819811 |
| 62 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15927971 |
| 63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.10486810 |
| 64 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.07269335 |
| 65 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.06507550 |
| 66 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.06061766 |
| 67 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03044850 |
| 68 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.02647540 |
| 69 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.00940249 |
| 70 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.00258709 |
| 71 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.99424177 |
| 72 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96763284 |
| 73 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.95981321 |
| 74 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.95454377 |
| 75 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.94974949 |
| 76 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.94686352 |
| 77 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.93020199 |
| 78 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.92469561 |
| 79 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.92380651 |
| 80 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.91409655 |
| 81 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90761293 |
| 82 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.90543230 |
| 83 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.87354287 |
| 84 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.86545900 |
| 85 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.85130881 |
| 86 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.83422098 |
| 87 | MYC_22102868_ChIP-Seq_BL_Human | 0.82376224 |
| 88 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.81983811 |
| 89 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.80429231 |
| 90 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.79987720 |
| 91 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.79848300 |
| 92 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.79066529 |
| 93 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.76684367 |
| 94 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.75545271 |
| 95 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.71759816 |
| 96 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.71674622 |
| 97 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.70346507 |
| 98 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.66858611 |
| 99 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.64452730 |
| 100 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.61158136 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 6.79176315 |
| 2 | MP0003693_abnormal_embryo_hatching | 5.36021748 |
| 3 | MP0003111_abnormal_nucleus_morphology | 5.11418139 |
| 4 | MP0008057_abnormal_DNA_replication | 4.73617883 |
| 5 | MP0008058_abnormal_DNA_repair | 4.70049383 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 4.67717221 |
| 7 | MP0003077_abnormal_cell_cycle | 4.27066478 |
| 8 | MP0008932_abnormal_embryonic_tissue | 3.44009992 |
| 9 | MP0008007_abnormal_cellular_replicative | 2.92847382 |
| 10 | MP0009697_abnormal_copulation | 2.82767908 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.55954441 |
| 12 | MP0003786_premature_aging | 2.33336059 |
| 13 | MP0001730_embryonic_growth_arrest | 2.33142821 |
| 14 | MP0000350_abnormal_cell_proliferation | 2.19803263 |
| 15 | MP0004147_increased_porphyrin_level | 2.13799155 |
| 16 | MP0003718_maternal_effect | 2.04164905 |
| 17 | MP0010307_abnormal_tumor_latency | 1.97156527 |
| 18 | MP0006035_abnormal_mitochondrial_morpho | 1.78616280 |
| 19 | MP0002396_abnormal_hematopoietic_system | 1.73667571 |
| 20 | MP0001697_abnormal_embryo_size | 1.71299802 |
| 21 | MP0010352_gastrointestinal_tract_polyps | 1.65728905 |
| 22 | MP0000313_abnormal_cell_death | 1.63737741 |
| 23 | MP0002080_prenatal_lethality | 1.63190115 |
| 24 | MP0005380_embryogenesis_phenotype | 1.62373797 |
| 25 | MP0001672_abnormal_embryogenesis/_devel | 1.62373797 |
| 26 | MP0006036_abnormal_mitochondrial_physio | 1.56590322 |
| 27 | MP0002019_abnormal_tumor_incidence | 1.49601256 |
| 28 | MP0000358_abnormal_cell_content/ | 1.45335224 |
| 29 | MP0008877_abnormal_DNA_methylation | 1.45268122 |
| 30 | MP0002210_abnormal_sex_determination | 1.42005837 |
| 31 | MP0003984_embryonic_growth_retardation | 1.30319451 |
| 32 | MP0001929_abnormal_gametogenesis | 1.27766242 |
| 33 | MP0002088_abnormal_embryonic_growth/wei | 1.23769562 |
| 34 | MP0002085_abnormal_embryonic_tissue | 1.23013796 |
| 35 | MP0003186_abnormal_redox_activity | 1.21438595 |
| 36 | MP0003941_abnormal_skin_development | 1.19705442 |
| 37 | MP0009672_abnormal_birth_weight | 1.18740517 |
| 38 | MP0001145_abnormal_male_reproductive | 1.14493882 |
| 39 | MP0001346_abnormal_lacrimal_gland | 1.14275779 |
| 40 | MP0002086_abnormal_extraembryonic_tissu | 1.11471004 |
| 41 | MP0005501_abnormal_skin_physiology | 1.08369899 |
| 42 | MP0003890_abnormal_embryonic-extraembry | 1.05423432 |
| 43 | MP0002084_abnormal_developmental_patter | 1.04804269 |
| 44 | MP0002877_abnormal_melanocyte_morpholog | 1.04476197 |
| 45 | MP0000653_abnormal_sex_gland | 1.04280255 |
| 46 | MP0000490_abnormal_crypts_of | 1.03628717 |
| 47 | MP0004185_abnormal_adipocyte_glucose | 1.00801484 |
| 48 | MP0001727_abnormal_embryo_implantation | 1.00491991 |
| 49 | MP0002796_impaired_skin_barrier | 1.00121022 |
| 50 | MP0001529_abnormal_vocalization | 0.98296930 |
| 51 | MP0003315_abnormal_perineum_morphology | 0.97222861 |
| 52 | MP0002163_abnormal_gland_morphology | 0.96152594 |
| 53 | MP0001881_abnormal_mammary_gland | 0.95066491 |
| 54 | MP0004197_abnormal_fetal_growth/weight/ | 0.94690206 |
| 55 | MP0005384_cellular_phenotype | 0.93529230 |
| 56 | MP0001661_extended_life_span | 0.92642692 |
| 57 | MP0001119_abnormal_female_reproductive | 0.90902189 |
| 58 | MP0002160_abnormal_reproductive_system | 0.89104278 |
| 59 | MP0001764_abnormal_homeostasis | 0.86632301 |
| 60 | MP0002006_tumorigenesis | 0.83136623 |
| 61 | MP0005621_abnormal_cell_physiology | 0.82192706 |
| 62 | MP0000703_abnormal_thymus_morphology | 0.80319237 |
| 63 | MP0000372_irregular_coat_pigmentation | 0.71543725 |
| 64 | MP0003950_abnormal_plasma_membrane | 0.71429118 |
| 65 | MP0002398_abnormal_bone_marrow | 0.71089619 |
| 66 | MP0003699_abnormal_female_reproductive | 0.70171414 |
| 67 | MP0002166_altered_tumor_susceptibility | 0.69830888 |
| 68 | MP0001293_anophthalmia | 0.69658902 |
| 69 | MP0009703_decreased_birth_body | 0.68200973 |
| 70 | MP0001853_heart_inflammation | 0.67649838 |
| 71 | MP0010234_abnormal_vibrissa_follicle | 0.67520157 |
| 72 | MP0000689_abnormal_spleen_morphology | 0.67489331 |
| 73 | MP0000627_abnormal_mammary_gland | 0.66869432 |
| 74 | MP0006292_abnormal_olfactory_placode | 0.66846021 |
| 75 | MP0002722_abnormal_immune_system | 0.66307792 |
| 76 | MP0008995_early_reproductive_senescence | 0.66304808 |
| 77 | MP0003698_abnormal_male_reproductive | 0.66138751 |
| 78 | MP0004233_abnormal_muscle_weight | 0.66118763 |
| 79 | MP0002009_preneoplasia | 0.64999369 |
| 80 | MP0003943_abnormal_hepatobiliary_system | 0.64772892 |
| 81 | MP0003567_abnormal_fetal_cardiomyocyte | 0.63453579 |
| 82 | MP0003656_abnormal_erythrocyte_physiolo | 0.62610837 |
| 83 | MP0002161_abnormal_fertility/fecundity | 0.62527715 |
| 84 | MP0003221_abnormal_cardiomyocyte_apopto | 0.61956433 |
| 85 | MP0009333_abnormal_splenocyte_physiolog | 0.61805577 |
| 86 | MP0002111_abnormal_tail_morphology | 0.61475452 |
| 87 | MP0005379_endocrine/exocrine_gland_phen | 0.59352060 |
| 88 | MP0004808_abnormal_hematopoietic_stem | 0.58929738 |
| 89 | MP0008260_abnormal_autophagy | 0.56100047 |
| 90 | MP0002429_abnormal_blood_cell | 0.55431892 |
| 91 | MP0005389_reproductive_system_phenotype | 0.54615178 |
| 92 | MP0006072_abnormal_retinal_apoptosis | 0.53891955 |
| 93 | MP0000598_abnormal_liver_morphology | 0.52189995 |
| 94 | MP0003763_abnormal_thymus_physiology | 0.52007588 |
| 95 | MP0008789_abnormal_olfactory_epithelium | 0.51420702 |
| 96 | MP0005451_abnormal_body_composition | 0.50787400 |
| 97 | MP0005395_other_phenotype | 0.50307193 |
| 98 | MP0002970_abnormal_white_adipose | 0.50248712 |
| 99 | MP0005266_abnormal_metabolism | 0.49193934 |
| 100 | MP0003937_abnormal_limbs/digits/tail_de | 0.46999607 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 7.09592381 |
| 2 | Chromsome breakage (HP:0040012) | 6.49594201 |
| 3 | Abnormality of the preputium (HP:0100587) | 4.29660797 |
| 4 | Meckel diverticulum (HP:0002245) | 4.27802255 |
| 5 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 4.20773801 |
| 6 | Abnormality of chromosome stability (HP:0003220) | 4.19286297 |
| 7 | Birth length less than 3rd percentile (HP:0003561) | 4.13055942 |
| 8 | Abnormality of the ileum (HP:0001549) | 4.05503573 |
| 9 | Microvesicular hepatic steatosis (HP:0001414) | 3.63489111 |
| 10 | Small intestinal stenosis (HP:0012848) | 3.58868179 |
| 11 | Duodenal stenosis (HP:0100867) | 3.58868179 |
| 12 | Abnormality of glycolysis (HP:0004366) | 3.46433914 |
| 13 | Increased serum pyruvate (HP:0003542) | 3.33257923 |
| 14 | Multiple enchondromatosis (HP:0005701) | 3.09421603 |
| 15 | Medulloblastoma (HP:0002885) | 3.08067923 |
| 16 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.04647967 |
| 17 | Myelodysplasia (HP:0002863) | 2.98151558 |
| 18 | Abnormality of the carotid arteries (HP:0005344) | 2.92228892 |
| 19 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.81919440 |
| 20 | Abnormality of the duodenum (HP:0002246) | 2.81758047 |
| 21 | Abnormality of the labia minora (HP:0012880) | 2.79680828 |
| 22 | Clubbing of toes (HP:0100760) | 2.74400711 |
| 23 | Ependymoma (HP:0002888) | 2.72731590 |
| 24 | Increased nuchal translucency (HP:0010880) | 2.71565565 |
| 25 | Embryonal renal neoplasm (HP:0011794) | 2.63444753 |
| 26 | Acute encephalopathy (HP:0006846) | 2.55767423 |
| 27 | Abnormal gallbladder physiology (HP:0012438) | 2.51573716 |
| 28 | Cholecystitis (HP:0001082) | 2.51573716 |
| 29 | Abnormal lung lobation (HP:0002101) | 2.47416730 |
| 30 | Carpal bone hypoplasia (HP:0001498) | 2.46270317 |
| 31 | Reduced antithrombin III activity (HP:0001976) | 2.41312433 |
| 32 | Acute necrotizing encephalopathy (HP:0006965) | 2.37917754 |
| 33 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.36128213 |
| 34 | Pancytopenia (HP:0001876) | 2.35605063 |
| 35 | Increased serum lactate (HP:0002151) | 2.34732507 |
| 36 | Sloping forehead (HP:0000340) | 2.32019200 |
| 37 | Aplastic anemia (HP:0001915) | 2.27850741 |
| 38 | Absent radius (HP:0003974) | 2.27836617 |
| 39 | Reticulocytopenia (HP:0001896) | 2.27218236 |
| 40 | Increased hepatocellular lipid droplets (HP:0006565) | 2.27125260 |
| 41 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.26475200 |
| 42 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.26475200 |
| 43 | Single umbilical artery (HP:0001195) | 2.26475200 |
| 44 | Volvulus (HP:0002580) | 2.22313339 |
| 45 | Increased CSF lactate (HP:0002490) | 2.21653984 |
| 46 | Bone marrow hypocellularity (HP:0005528) | 2.21445235 |
| 47 | Colon cancer (HP:0003003) | 2.19716994 |
| 48 | Cafe-au-lait spot (HP:0000957) | 2.19525660 |
| 49 | IgM deficiency (HP:0002850) | 2.17738311 |
| 50 | Rhabdomyosarcoma (HP:0002859) | 2.17035161 |
| 51 | Type I transferrin isoform profile (HP:0003642) | 2.16754940 |
| 52 | Hypoplastic pelvis (HP:0008839) | 2.13327655 |
| 53 | Abnormality of the umbilical cord (HP:0010881) | 2.12020722 |
| 54 | Absent forearm bone (HP:0003953) | 2.11191469 |
| 55 | Aplasia involving forearm bones (HP:0009822) | 2.11191469 |
| 56 | Triphalangeal thumb (HP:0001199) | 2.10093069 |
| 57 | Horseshoe kidney (HP:0000085) | 2.09777156 |
| 58 | Lipid accumulation in hepatocytes (HP:0006561) | 2.07916249 |
| 59 | Cerebral hypomyelination (HP:0006808) | 2.06174684 |
| 60 | Neoplasm of the adrenal gland (HP:0100631) | 2.04963115 |
| 61 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.04666466 |
| 62 | Postnatal microcephaly (HP:0005484) | 2.04148212 |
| 63 | Agammaglobulinemia (HP:0004432) | 2.00961076 |
| 64 | Cortical dysplasia (HP:0002539) | 2.00875393 |
| 65 | Mitochondrial inheritance (HP:0001427) | 2.00865588 |
| 66 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.00367309 |
| 67 | Premature ovarian failure (HP:0008209) | 1.99098807 |
| 68 | Glioma (HP:0009733) | 1.97732355 |
| 69 | Hepatocellular necrosis (HP:0001404) | 1.97720138 |
| 70 | Secondary amenorrhea (HP:0000869) | 1.96938625 |
| 71 | Hepatic necrosis (HP:0002605) | 1.96689887 |
| 72 | Ectopic kidney (HP:0000086) | 1.96354638 |
| 73 | Short thumb (HP:0009778) | 1.95199932 |
| 74 | Irregular epiphyses (HP:0010582) | 1.94726397 |
| 75 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.93456333 |
| 76 | Abnormality of alanine metabolism (HP:0010916) | 1.93456333 |
| 77 | Hyperalaninemia (HP:0003348) | 1.93456333 |
| 78 | Cerebral edema (HP:0002181) | 1.92119603 |
| 79 | Selective tooth agenesis (HP:0001592) | 1.91948254 |
| 80 | Breast hypoplasia (HP:0003187) | 1.91763759 |
| 81 | Lactic acidosis (HP:0003128) | 1.91405175 |
| 82 | Choanal atresia (HP:0000453) | 1.90362446 |
| 83 | Arteriovenous malformation (HP:0100026) | 1.90289157 |
| 84 | Cleft eyelid (HP:0000625) | 1.89166892 |
| 85 | Poikiloderma (HP:0001029) | 1.87678743 |
| 86 | Rough bone trabeculation (HP:0100670) | 1.87084245 |
| 87 | Facial cleft (HP:0002006) | 1.85477796 |
| 88 | Proximal placement of thumb (HP:0009623) | 1.85297517 |
| 89 | Neoplasm of the colon (HP:0100273) | 1.85065365 |
| 90 | Microglossia (HP:0000171) | 1.84206903 |
| 91 | Abnormality of the anterior horn cell (HP:0006802) | 1.83865345 |
| 92 | Degeneration of anterior horn cells (HP:0002398) | 1.83865345 |
| 93 | Embryonal neoplasm (HP:0002898) | 1.82567671 |
| 94 | Squamous cell carcinoma (HP:0002860) | 1.81356896 |
| 95 | Ovarian neoplasm (HP:0100615) | 1.81095455 |
| 96 | Agnosia (HP:0010524) | 1.80958630 |
| 97 | Abnormal protein glycosylation (HP:0012346) | 1.80650745 |
| 98 | Abnormal glycosylation (HP:0012345) | 1.80650745 |
| 99 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.80650745 |
| 100 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.80650745 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDC7 | 4.54285413 |
| 2 | BUB1 | 4.11676402 |
| 3 | ZAK | 3.60073110 |
| 4 | VRK2 | 3.57831039 |
| 5 | EIF2AK1 | 3.53887410 |
| 6 | NEK1 | 3.52220071 |
| 7 | TTK | 3.29132990 |
| 8 | PLK4 | 3.09873254 |
| 9 | SRPK1 | 3.02916013 |
| 10 | WEE1 | 2.93876479 |
| 11 | VRK1 | 2.75013995 |
| 12 | PBK | 2.61933647 |
| 13 | SCYL2 | 2.50740748 |
| 14 | EIF2AK3 | 2.42744092 |
| 15 | TSSK6 | 2.30463773 |
| 16 | PLK3 | 1.95959278 |
| 17 | PLK1 | 1.90106118 |
| 18 | MST4 | 1.85601197 |
| 19 | BRSK2 | 1.78328197 |
| 20 | BRSK1 | 1.73260908 |
| 21 | CHEK2 | 1.70865152 |
| 22 | CCNB1 | 1.57612794 |
| 23 | NME2 | 1.56020522 |
| 24 | AURKB | 1.55756775 |
| 25 | ATR | 1.54609048 |
| 26 | STK16 | 1.51793342 |
| 27 | SMG1 | 1.50359076 |
| 28 | TAF1 | 1.45418392 |
| 29 | TLK1 | 1.41004610 |
| 30 | CDK7 | 1.40523020 |
| 31 | TRIM28 | 1.38514581 |
| 32 | AURKA | 1.36564977 |
| 33 | TESK2 | 1.26706977 |
| 34 | CDK8 | 1.26155823 |
| 35 | MKNK1 | 1.24661712 |
| 36 | EIF2AK2 | 1.15052901 |
| 37 | NUAK1 | 1.05319372 |
| 38 | NEK2 | 1.03664823 |
| 39 | CHEK1 | 1.03361453 |
| 40 | NME1 | 1.01714938 |
| 41 | MKNK2 | 0.99987982 |
| 42 | PAK4 | 0.96603994 |
| 43 | MAP3K8 | 0.87213482 |
| 44 | PASK | 0.85961240 |
| 45 | ATM | 0.84109048 |
| 46 | DAPK1 | 0.84034665 |
| 47 | KDR | 0.83891947 |
| 48 | BCKDK | 0.83613767 |
| 49 | STK4 | 0.81451020 |
| 50 | RPS6KB2 | 0.76259340 |
| 51 | CSNK1G3 | 0.72840247 |
| 52 | CDK4 | 0.66849722 |
| 53 | ALK | 0.65454568 |
| 54 | STK10 | 0.64110516 |
| 55 | BRAF | 0.62111147 |
| 56 | NEK9 | 0.60951642 |
| 57 | CDK1 | 0.58210062 |
| 58 | MELK | 0.57899136 |
| 59 | CSNK1G1 | 0.57215959 |
| 60 | CDK9 | 0.55792300 |
| 61 | MAP3K12 | 0.55609120 |
| 62 | PNCK | 0.53782963 |
| 63 | CSNK2A1 | 0.52365553 |
| 64 | CDK2 | 0.52348729 |
| 65 | MST1R | 0.52193894 |
| 66 | CSNK1A1L | 0.51876418 |
| 67 | CLK1 | 0.51238808 |
| 68 | CSNK2A2 | 0.50791108 |
| 69 | RPS6KA5 | 0.46826330 |
| 70 | CDK6 | 0.46104653 |
| 71 | CSNK1G2 | 0.43989302 |
| 72 | BCR | 0.43757173 |
| 73 | AKT2 | 0.42981360 |
| 74 | CDK18 | 0.42386186 |
| 75 | ARAF | 0.40284744 |
| 76 | PAK1 | 0.40232720 |
| 77 | CDK15 | 0.39184569 |
| 78 | CDK14 | 0.37975241 |
| 79 | CDK11A | 0.37855929 |
| 80 | CDK12 | 0.37593838 |
| 81 | RPS6KA4 | 0.35704328 |
| 82 | MAPKAPK5 | 0.34592740 |
| 83 | STK3 | 0.30965210 |
| 84 | PLK2 | 0.29541573 |
| 85 | PIM1 | 0.28802266 |
| 86 | TAOK1 | 0.28770772 |
| 87 | BMPR1B | 0.27954454 |
| 88 | CDK3 | 0.26994527 |
| 89 | DAPK3 | 0.26614594 |
| 90 | SIK3 | 0.25857997 |
| 91 | ERBB3 | 0.25081652 |
| 92 | PRKDC | 0.24193724 |
| 93 | PDK2 | 0.23790690 |
| 94 | RAF1 | 0.23529655 |
| 95 | PIM2 | 0.23050835 |
| 96 | PRKCI | 0.20600762 |
| 97 | LATS1 | 0.20037887 |
| 98 | CSNK1E | 0.17163792 |
| 99 | TESK1 | 0.15800010 |
| 100 | TAOK2 | 0.15122671 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 5.78480069 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 5.01531641 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.85320966 |
| 4 | Base excision repair_Homo sapiens_hsa03410 | 3.43168517 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 3.21548778 |
| 6 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.92042978 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.75979841 |
| 8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.75313951 |
| 9 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.74746826 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.64253300 |
| 11 | Cell cycle_Homo sapiens_hsa04110 | 2.61469352 |
| 12 | Spliceosome_Homo sapiens_hsa03040 | 2.26061299 |
| 13 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.23940991 |
| 14 | RNA transport_Homo sapiens_hsa03013 | 2.16774831 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.11728360 |
| 16 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.04040138 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 1.91502847 |
| 18 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.87284693 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.59736803 |
| 20 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.53088912 |
| 21 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.52761063 |
| 22 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.47061285 |
| 23 | Ribosome_Homo sapiens_hsa03010 | 1.46523575 |
| 24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.45334164 |
| 25 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.39513760 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.35439433 |
| 27 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.34423488 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.33986494 |
| 29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.32188843 |
| 30 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.31187958 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.25337015 |
| 32 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.24071931 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.20080160 |
| 34 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.18261915 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.10790060 |
| 36 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.06930609 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.06696078 |
| 38 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.06241291 |
| 39 | Parkinsons disease_Homo sapiens_hsa05012 | 0.95154799 |
| 40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.94886388 |
| 41 | Alcoholism_Homo sapiens_hsa05034 | 0.87364824 |
| 42 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.86617556 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.86387538 |
| 44 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.85895236 |
| 45 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.85387221 |
| 46 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.82398583 |
| 47 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.81775751 |
| 48 | Huntingtons disease_Homo sapiens_hsa05016 | 0.79468479 |
| 49 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.76622935 |
| 50 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.75982733 |
| 51 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.75661253 |
| 52 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.72856139 |
| 53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.71093478 |
| 54 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.68634260 |
| 55 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.68535453 |
| 56 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.68512310 |
| 57 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65858253 |
| 58 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.65515886 |
| 59 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.61247050 |
| 60 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.58915173 |
| 61 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.57060588 |
| 62 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.56584518 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.55529266 |
| 64 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.55327591 |
| 65 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.47382622 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46444846 |
| 67 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.41701847 |
| 68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.39267352 |
| 69 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.38192432 |
| 70 | Alzheimers disease_Homo sapiens_hsa05010 | 0.34785155 |
| 71 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.33510514 |
| 72 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.33141328 |
| 73 | HTLV-I infection_Homo sapiens_hsa05166 | 0.31669737 |
| 74 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.26938128 |
| 75 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.26807824 |
| 76 | Galactose metabolism_Homo sapiens_hsa00052 | 0.21647594 |
| 77 | Thyroid cancer_Homo sapiens_hsa05216 | 0.21522087 |
| 78 | Lysine degradation_Homo sapiens_hsa00310 | 0.20981466 |
| 79 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.19675007 |
| 80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.16777746 |
| 81 | Peroxisome_Homo sapiens_hsa04146 | 0.16120383 |
| 82 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.15614774 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.14166696 |
| 84 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.12473491 |
| 85 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.12452462 |
| 86 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.12299835 |
| 87 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.11727766 |
| 88 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.10447470 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.10281535 |
| 90 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.09432024 |
| 91 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.08823248 |
| 92 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.08271317 |
| 93 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.07177875 |
| 94 | Hepatitis B_Homo sapiens_hsa05161 | 0.06217901 |
| 95 | Apoptosis_Homo sapiens_hsa04210 | 0.05627678 |
| 96 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.05179697 |
| 97 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.04633106 |
| 98 | Bladder cancer_Homo sapiens_hsa05219 | 0.00166000 |
| 99 | Measles_Homo sapiens_hsa05162 | -0.0500240 |
| 100 | Colorectal cancer_Homo sapiens_hsa05210 | -0.0216940 |

