DHX15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.63475082
2nuclear pore organization (GO:0006999)5.54924642
3DNA unwinding involved in DNA replication (GO:0006268)5.40991783
4establishment of integrated proviral latency (GO:0075713)4.82773029
5mitotic sister chromatid cohesion (GO:0007064)4.46270375
6protein localization to kinetochore (GO:0034501)4.42297435
7pore complex assembly (GO:0046931)4.38691684
8double-strand break repair via nonhomologous end joining (GO:0006303)4.12488873
9non-recombinational repair (GO:0000726)4.12488873
10mitotic chromosome condensation (GO:0007076)4.10375517
11mitotic nuclear envelope disassembly (GO:0007077)4.09050333
12DNA duplex unwinding (GO:0032508)3.94840992
13DNA geometric change (GO:0032392)3.93243873
14regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.91219264
15membrane disassembly (GO:0030397)3.86940764
16nuclear envelope disassembly (GO:0051081)3.86940764
17regulation of RNA export from nucleus (GO:0046831)3.74437991
18DNA replication-dependent nucleosome assembly (GO:0006335)3.71948586
19DNA replication-dependent nucleosome organization (GO:0034723)3.71948586
20DNA ligation (GO:0006266)3.71528250
21pre-miRNA processing (GO:0031054)3.68965221
22protein localization to chromosome, centromeric region (GO:0071459)3.68293179
23folic acid-containing compound biosynthetic process (GO:0009396)3.67630470
24sister chromatid segregation (GO:0000819)3.63746005
25heterochromatin organization (GO:0070828)3.60437218
26negative regulation of chromosome segregation (GO:0051985)3.59798188
27negative regulation of histone methylation (GO:0031061)3.57847795
28spindle checkpoint (GO:0031577)3.56624452
29regulation of histone H3-K9 methylation (GO:0051570)3.56496151
30mitotic spindle checkpoint (GO:0071174)3.55301471
31establishment of viral latency (GO:0019043)3.55297849
32IMP biosynthetic process (GO:0006188)3.54781525
33DNA replication initiation (GO:0006270)3.54409432
34regulation of sister chromatid cohesion (GO:0007063)3.53977480
35negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.51879157
36negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.51879157
37negative regulation of mitotic sister chromatid segregation (GO:0033048)3.51879157
38negative regulation of mitotic sister chromatid separation (GO:2000816)3.51879157
39negative regulation of sister chromatid segregation (GO:0033046)3.51879157
40negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.47854324
41dosage compensation (GO:0007549)3.45078978
42regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.43859491
43DNA strand elongation involved in DNA replication (GO:0006271)3.43188813
44chromatin assembly (GO:0031497)3.42845139
45protein complex localization (GO:0031503)3.42315798
46regulation of spindle organization (GO:0090224)3.42134690
47mitotic spindle assembly checkpoint (GO:0007094)3.39424747
48spindle assembly checkpoint (GO:0071173)3.36009738
49regulation of mitotic sister chromatid separation (GO:0010965)3.35168309
50regulation of mitotic sister chromatid segregation (GO:0033047)3.35168309
51regulation of sister chromatid segregation (GO:0033045)3.35168309
52negative regulation of RNA splicing (GO:0033119)3.33330287
53purine nucleobase biosynthetic process (GO:0009113)3.28576978
54regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.27999932
55mitotic metaphase plate congression (GO:0007080)3.26015991
56DNA strand elongation (GO:0022616)3.24662578
57translesion synthesis (GO:0019985)3.24121007
58kinetochore organization (GO:0051383)3.23104741
59positive regulation of chromosome segregation (GO:0051984)3.22443374
60mitotic sister chromatid segregation (GO:0000070)3.19930739
61mRNA stabilization (GO:0048255)3.19446115
62RNA stabilization (GO:0043489)3.19446115
63alternative mRNA splicing, via spliceosome (GO:0000380)3.16264588
64DNA conformation change (GO:0071103)3.15606819
65chromatin assembly or disassembly (GO:0006333)3.15519043
66regulation of mitotic spindle organization (GO:0060236)3.15243490
67DNA topological change (GO:0006265)3.14781452
68metaphase plate congression (GO:0051310)3.09414265
69cellular protein complex localization (GO:0034629)3.08983174
70histone exchange (GO:0043486)3.08754895
71regulation of translational fidelity (GO:0006450)3.08694398
72regulation of DNA endoreduplication (GO:0032875)3.08630414
73formation of translation preinitiation complex (GO:0001731)3.08566062
74positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.07647946
75positive regulation of mitotic sister chromatid separation (GO:1901970)3.07647946
76positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.07647946
77IMP metabolic process (GO:0046040)3.07252866
78regulation of centriole replication (GO:0046599)3.07107108
79nuclear envelope organization (GO:0006998)3.06661736
80chromosome segregation (GO:0007059)3.04651684
81negative regulation of mRNA processing (GO:0050686)3.04129465
82nucleobase biosynthetic process (GO:0046112)3.00746017
83RNA export from nucleus (GO:0006405)2.99026724
84termination of RNA polymerase II transcription (GO:0006369)2.98841015
85mitotic recombination (GO:0006312)2.97783028
86mRNA export from nucleus (GO:0006406)2.97568030
87DNA replication-independent nucleosome organization (GO:0034724)2.96917970
88DNA replication-independent nucleosome assembly (GO:0006336)2.96917970
89positive regulation of cell cycle checkpoint (GO:1901978)2.95898209
90telomere maintenance via telomere lengthening (GO:0010833)2.95355238
91ribosome assembly (GO:0042255)2.94871927
92regulation of centrosome duplication (GO:0010824)2.94823919
93regulation of translational termination (GO:0006449)2.92914183
94regulation of nucleobase-containing compound transport (GO:0032239)2.92199601
95protein localization to chromosome (GO:0034502)2.91306497
96chromatin remodeling at centromere (GO:0031055)2.88796216
97telomere maintenance via semi-conservative replication (GO:0032201)2.88769390
98regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.87078880
99negative regulation of mRNA metabolic process (GO:1903312)2.86391391
100mRNA transport (GO:0051028)2.84640343
101histone H2A monoubiquitination (GO:0035518)2.84552926
102regulation of centrosome cycle (GO:0046605)2.83898698
103spliceosomal tri-snRNP complex assembly (GO:0000244)2.83089075
104chromosome condensation (GO:0030261)2.82928361
105CENP-A containing nucleosome assembly (GO:0034080)2.79934526
106meiotic chromosome segregation (GO:0045132)2.79466792
107regulation of chromosome segregation (GO:0051983)2.79156984
108NLS-bearing protein import into nucleus (GO:0006607)2.78112176
109establishment of chromosome localization (GO:0051303)2.76986179
110ATP-dependent chromatin remodeling (GO:0043044)2.76717753
111telomere maintenance via recombination (GO:0000722)2.76344763
112peptidyl-lysine dimethylation (GO:0018027)2.73578085
113DNA replication checkpoint (GO:0000076)2.73492602
114regulation of posttranscriptional gene silencing (GO:0060147)2.73266606
115regulation of gene silencing by miRNA (GO:0060964)2.73266606
116regulation of gene silencing by RNA (GO:0060966)2.73266606
1173-UTR-mediated mRNA stabilization (GO:0070935)2.70880773
118regulation of mRNA stability (GO:0043488)2.70578245
119attachment of spindle microtubules to kinetochore (GO:0008608)2.69758523
120negative regulation of DNA repair (GO:0045738)2.68934170
121somatic diversification of immune receptors via somatic mutation (GO:0002566)2.67032506
122somatic hypermutation of immunoglobulin genes (GO:0016446)2.67032506
123regulation of helicase activity (GO:0051095)2.66795834
124glucocorticoid receptor signaling pathway (GO:0042921)2.66613838
125positive regulation of SMAD protein import into nucleus (GO:0060391)2.66170547
126regulation of mitotic metaphase/anaphase transition (GO:0030071)2.65513520
127monoubiquitinated protein deubiquitination (GO:0035520)2.64865769
128maturation of SSU-rRNA (GO:0030490)2.64611320
129postreplication repair (GO:0006301)2.64311778
130mRNA splicing, via spliceosome (GO:0000398)2.64118434

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.30260211
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.08639834
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.03381609
4* MYC_18555785_ChIP-Seq_MESCs_Mouse3.41576619
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.14413020
6MYC_22102868_ChIP-Seq_BL_Human2.73967698
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.70418626
8* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.64300451
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.56757320
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.56064695
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.53145743
12AR_21909140_ChIP-Seq_LNCAP_Human2.48338659
13E2F1_21310950_ChIP-Seq_MCF-7_Human2.40265459
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.18590188
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06760374
16SALL1_21062744_ChIP-ChIP_HESCs_Human2.03470886
17E2F7_22180533_ChIP-Seq_HELA_Human10.6067918
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.76985121
19XRN2_22483619_ChIP-Seq_HELA_Human1.76606087
20ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.72252090
21TP63_19390658_ChIP-ChIP_HaCaT_Human1.71381921
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70946336
23CIITA_25753668_ChIP-Seq_RAJI_Human1.69767658
24MYC_18358816_ChIP-ChIP_MESCs_Mouse1.65986232
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.64093006
26MYCN_18555785_ChIP-Seq_MESCs_Mouse1.63028251
27JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.62464190
28THAP11_20581084_ChIP-Seq_MESCs_Mouse1.61071156
29MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.54279352
30ESR1_15608294_ChIP-ChIP_MCF-7_Human1.47105202
31FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.46687172
32SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.45405472
33VDR_21846776_ChIP-Seq_THP-1_Human1.45302825
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43416442
35VDR_23849224_ChIP-Seq_CD4+_Human1.41514404
36* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41061514
37YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.39539538
38KDM5A_27292631_Chip-Seq_BREAST_Human1.39460143
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37081424
40EST1_17652178_ChIP-ChIP_JURKAT_Human1.36591797
41ELK1_19687146_ChIP-ChIP_HELA_Human1.34751465
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.34157794
43FOXP3_21729870_ChIP-Seq_TREG_Human1.32498032
44CREB1_15753290_ChIP-ChIP_HEK293T_Human1.30787928
45TTF2_22483619_ChIP-Seq_HELA_Human1.29365218
46POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26664704
47* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26530943
48CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.25697616
49NANOG_18555785_ChIP-Seq_MESCs_Mouse1.25451778
50SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.24173057
51CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.23733055
52TCF7_22412390_ChIP-Seq_EML_Mouse1.23325174
53PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18674381
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18499340
55ETS1_20019798_ChIP-Seq_JURKAT_Human1.18316656
56TFEB_21752829_ChIP-Seq_HELA_Human1.16743252
57KLF4_18555785_ChIP-Seq_MESCs_Mouse1.16522031
58SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.15197417
59CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.15002619
60HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.12664148
61HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.10377208
62SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10017609
63SOX17_20123909_ChIP-Seq_XEN_Mouse1.09922594
64* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09814081
65* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.09723336
66NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09153684
67DCP1A_22483619_ChIP-Seq_HELA_Human1.08380134
68HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.07993922
69DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07814348
70MYB_26560356_Chip-Seq_TH2_Human1.07811815
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.07528140
72NANOG_16153702_ChIP-ChIP_HESCs_Human1.07488553
73UTX_26944678_Chip-Seq_JUKART_Human1.07416403
74* CHD1_26751641_Chip-Seq_LNCaP_Human1.06973583
75STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.06718283
76MYB_26560356_Chip-Seq_TH1_Human1.05536727
77* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.05431680
78GABP_19822575_ChIP-Seq_HepG2_Human1.04881890
79NANOG_21062744_ChIP-ChIP_HESCs_Human1.04652987
80MAF_26560356_Chip-Seq_TH1_Human1.04396637
81CLOCK_20551151_ChIP-Seq_293T_Human1.04167365
82KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.03524512
83ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.02610074
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02344953
85ELF1_17652178_ChIP-ChIP_JURKAT_Human1.01953386
86SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01652154
87KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01076617
88KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.01072686
89E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00793267
90SOX2_16153702_ChIP-ChIP_HESCs_Human1.00334631
91CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00260797
92ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99266125
93SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.99216878
94PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98872613
95TCF3_18692474_ChIP-Seq_MEFs_Mouse0.97994741
96HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.96980576
97* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94412153
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94148194
99NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.93986047
100HIF1A_21447827_ChIP-Seq_MCF-7_Human0.93982652
101GABP_17652178_ChIP-ChIP_JURKAT_Human0.93085104
102NOTCH1_21737748_ChIP-Seq_TLL_Human0.92969484
103POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.91940320
104CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.91121303
105WT1_19549856_ChIP-ChIP_CCG9911_Human0.90949694
106BRD4_27068464_Chip-Seq_AML-cells_Mouse0.90851113
107FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.90454846
108TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90235053
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.90039022
110MYC_18940864_ChIP-ChIP_HL60_Human0.89929106
111PKCTHETA_26484144_Chip-Seq_BREAST_Human0.89423280
112KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.89158925
113MYB_21317192_ChIP-Seq_ERMYB_Mouse0.88850658
114STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.87921102
115TP63_17297297_ChIP-ChIP_HaCaT_Human0.87709768
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87331519
117ERG_20887958_ChIP-Seq_HPC-7_Mouse0.86969977
118KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.86900360
119KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.86900360
120TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.82588734
121EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.82033035
122GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.81926037
123KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.81351453
124POU5F1_16153702_ChIP-ChIP_HESCs_Human0.80243595
125SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.79287841

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.53486598
2MP0003693_abnormal_embryo_hatching3.48070812
3MP0010352_gastrointestinal_tract_polyps3.30336787
4MP0008057_abnormal_DNA_replication3.30169168
5MP0003111_abnormal_nucleus_morphology3.13619874
6MP0004957_abnormal_blastocyst_morpholog3.08077828
7MP0003077_abnormal_cell_cycle2.99524277
8MP0003705_abnormal_hypodermis_morpholog2.54882194
9MP0010307_abnormal_tumor_latency2.45094155
10MP0005076_abnormal_cell_differentiation2.44366587
11MP0002396_abnormal_hematopoietic_system2.27077570
12MP0001730_embryonic_growth_arrest2.16675347
13MP0008007_abnormal_cellular_replicative2.16664979
14MP0003123_paternal_imprinting2.11228810
15MP0000350_abnormal_cell_proliferation2.08620238
16MP0008058_abnormal_DNA_repair2.06633523
17MP0004808_abnormal_hematopoietic_stem1.98063457
18MP0009697_abnormal_copulation1.89221721
19MP0004197_abnormal_fetal_growth/weight/1.87969140
20MP0010234_abnormal_vibrissa_follicle1.81293924
21MP0001672_abnormal_embryogenesis/_devel1.77853509
22MP0005380_embryogenesis_phenotype1.77853509
23MP0000569_abnormal_digit_pigmentation1.74472143
24MP0003221_abnormal_cardiomyocyte_apopto1.71241465
25MP0003984_embryonic_growth_retardation1.70653889
26MP0002088_abnormal_embryonic_growth/wei1.69473434
27MP0002084_abnormal_developmental_patter1.69120802
28MP0001697_abnormal_embryo_size1.65530087
29MP0002086_abnormal_extraembryonic_tissu1.65116052
30MP0008932_abnormal_embryonic_tissue1.64985159
31MP0000537_abnormal_urethra_morphology1.63764580
32MP0003121_genomic_imprinting1.56507179
33MP0006054_spinal_hemorrhage1.54950885
34MP0002085_abnormal_embryonic_tissue1.54934150
35MP0009053_abnormal_anal_canal1.52455659
36MP0002080_prenatal_lethality1.45459138
37MP0000490_abnormal_crypts_of1.43731230
38MP0010030_abnormal_orbit_morphology1.41463348
39MP0003890_abnormal_embryonic-extraembry1.39822078
40MP0003300_gastrointestinal_ulcer1.37731212
41MP0008877_abnormal_DNA_methylation1.36674287
42MP0003567_abnormal_fetal_cardiomyocyte1.36626452
43MP0009278_abnormal_bone_marrow1.35778172
44MP0000733_abnormal_muscle_development1.31617570
45MP0003566_abnormal_cell_adhesion1.30246352
46MP0001293_anophthalmia1.28648917
47MP0000703_abnormal_thymus_morphology1.23257335
48MP0002019_abnormal_tumor_incidence1.18525812
49MP0003763_abnormal_thymus_physiology1.17215058
50MP0002166_altered_tumor_susceptibility1.14776572
51MP0002796_impaired_skin_barrier1.14404340
52MP0000313_abnormal_cell_death1.11895351
53MP0000428_abnormal_craniofacial_morphol1.09888388
54MP0009703_decreased_birth_body1.09434897
55MP0005023_abnormal_wound_healing1.08551793
56MP0009672_abnormal_birth_weight1.08529748
57MP0002398_abnormal_bone_marrow1.07158389
58MP0001545_abnormal_hematopoietic_system1.05429208
59MP0005397_hematopoietic_system_phenotyp1.05429208
60MP0003718_maternal_effect1.04999994
61MP0002092_abnormal_eye_morphology1.04833487
62MP0003786_premature_aging1.04526810
63MP0001849_ear_inflammation1.04184838
64MP0002877_abnormal_melanocyte_morpholog1.03647804
65MP0001915_intracranial_hemorrhage1.02308808
66MP0005501_abnormal_skin_physiology1.01016856
67MP0003937_abnormal_limbs/digits/tail_de1.00068960
68MP0003315_abnormal_perineum_morphology0.96713785
69MP0004233_abnormal_muscle_weight0.96361650
70MP0001346_abnormal_lacrimal_gland0.96233930
71MP0002006_tumorigenesis0.95204666
72MP0003119_abnormal_digestive_system0.91816730
73MP0002722_abnormal_immune_system0.91784014
74MP0003115_abnormal_respiratory_system0.91541588
75MP0002697_abnormal_eye_size0.91495404
76MP0002925_abnormal_cardiovascular_devel0.90822931
77MP0000358_abnormal_cell_content/0.90496490
78MP0006035_abnormal_mitochondrial_morpho0.89762637
79MP0003935_abnormal_craniofacial_develop0.88523740
80MP0009333_abnormal_splenocyte_physiolog0.86446049
81MP0000432_abnormal_head_morphology0.85922888
82MP0002233_abnormal_nose_morphology0.85338445
83MP0003943_abnormal_hepatobiliary_system0.84415761
84MP0002111_abnormal_tail_morphology0.82982245
85MP0008438_abnormal_cutaneous_collagen0.82889047
86MP0000689_abnormal_spleen_morphology0.81049304
87MP0010678_abnormal_skin_adnexa0.79300303
88MP0008995_early_reproductive_senescence0.78925176
89MP0001727_abnormal_embryo_implantation0.78847341
90MP0003941_abnormal_skin_development0.78141899
91MP0000477_abnormal_intestine_morphology0.76368663
92MP0000647_abnormal_sebaceous_gland0.75878022
93MP0003861_abnormal_nervous_system0.74744069
94MP0003755_abnormal_palate_morphology0.74607620
95MP0004185_abnormal_adipocyte_glucose0.73957864
96MP0005621_abnormal_cell_physiology0.73533077
97MP0000579_abnormal_nail_morphology0.73464669
98MP0005257_abnormal_intraocular_pressure0.73429711
99MP0001299_abnormal_eye_distance/0.73327556
100MP0002429_abnormal_blood_cell0.72866451
101MP0003303_peritoneal_inflammation0.72835632
102MP0003448_altered_tumor_morphology0.72830510
103MP0001216_abnormal_epidermal_layer0.72717169
104MP0001177_atelectasis0.72609377
105MP0003091_abnormal_cell_migration0.72335603
106MP0001286_abnormal_eye_development0.72084149
107MP0002009_preneoplasia0.71591206
108MP0001661_extended_life_span0.71238145
109MP0000371_diluted_coat_color0.71115262
110MP0003385_abnormal_body_wall0.70162074
111MP0001800_abnormal_humoral_immune0.70002465
112MP0004264_abnormal_extraembryonic_tissu0.69154348
113MP0000716_abnormal_immune_system0.68631450
114MP0000377_abnormal_hair_follicle0.68056515
115MP0000858_altered_metastatic_potential0.67889089
116MP0000685_abnormal_immune_system0.67545847
117MP0002751_abnormal_autonomic_nervous0.67172508
118MP0004782_abnormal_surfactant_physiolog0.66987641
119MP0000383_abnormal_hair_follicle0.66408873
120MP0005384_cellular_phenotype0.66347044
121MP0002060_abnormal_skin_morphology0.66178697
122MP0000627_abnormal_mammary_gland0.65800484
123MP0002210_abnormal_sex_determination0.64906986
124MP0000465_gastrointestinal_hemorrhage0.64555429
125MP0005187_abnormal_penis_morphology0.64461475
126MP0003283_abnormal_digestive_organ0.63911211
127MP0002081_perinatal_lethality0.62646244
128MP0002254_reproductive_system_inflammat0.60676713
129MP0001145_abnormal_male_reproductive0.60617689
130MP0005394_taste/olfaction_phenotype0.60528387

Predicted human phenotypes

RankGene SetZ-score
1Nephroblastoma (Wilms tumor) (HP:0002667)3.64328983
2Cortical dysplasia (HP:0002539)3.54947171
3Embryonal renal neoplasm (HP:0011794)3.44720937
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.36328934
5Short 4th metacarpal (HP:0010044)3.36328934
6Colon cancer (HP:0003003)3.12126771
7Ependymoma (HP:0002888)3.09846686
8Volvulus (HP:0002580)3.04736060
9Proximal placement of thumb (HP:0009623)3.00359719
10Deviation of the thumb (HP:0009603)2.99904072
11Abnormality of the preputium (HP:0100587)2.98157238
12Medulloblastoma (HP:0002885)2.92936023
13Increased nuchal translucency (HP:0010880)2.88396792
14Selective tooth agenesis (HP:0001592)2.82220612
15Chromsome breakage (HP:0040012)2.75434543
16Microvesicular hepatic steatosis (HP:0001414)2.61778948
17Abnormal lung lobation (HP:0002101)2.59291726
18Multiple enchondromatosis (HP:0005701)2.57510455
19Spastic diplegia (HP:0001264)2.51704040
20Abnormality of the fingertips (HP:0001211)2.48981156
21Chromosomal breakage induced by crosslinking agents (HP:0003221)2.48819095
22Biliary tract neoplasm (HP:0100574)2.47113117
23Abnormality of the 4th metacarpal (HP:0010012)2.44053831
24High anterior hairline (HP:0009890)2.43524213
25Basal cell carcinoma (HP:0002671)2.40671264
26Abnormality of the astrocytes (HP:0100707)2.39376655
27Astrocytoma (HP:0009592)2.39376655
28Insidious onset (HP:0003587)2.35442320
29Termporal pattern (HP:0011008)2.35442320
30Progressive external ophthalmoplegia (HP:0000590)2.33415789
31Gastrointestinal carcinoma (HP:0002672)2.33217857
32Malignant gastrointestinal tract tumors (HP:0006749)2.33217857
33Abnormality of chromosome stability (HP:0003220)2.32317708
34Rhabdomyosarcoma (HP:0002859)2.28576924
35Subacute progressive viral hepatitis (HP:0006572)2.20565320
36Abnormality of the duodenum (HP:0002246)2.20339231
37Increased density of long bones (HP:0006392)2.19984750
38Reticulocytopenia (HP:0001896)2.16434920
39Shoulder girdle muscle weakness (HP:0003547)2.14746586
40Ectopic kidney (HP:0000086)2.14312250
41Leiomyosarcoma (HP:0100243)2.12729438
42Uterine leiomyosarcoma (HP:0002891)2.12729438
43Facial hemangioma (HP:0000329)2.12339198
44High pitched voice (HP:0001620)2.12298138
45Glioma (HP:0009733)2.12148426
46Embryonal neoplasm (HP:0002898)2.12100238
47Agnosia (HP:0010524)2.12098493
48Prominent nose (HP:0000448)2.11641401
49Absent radius (HP:0003974)2.10955651
50Long eyelashes (HP:0000527)2.09997957
51Birth length less than 3rd percentile (HP:0003561)2.09252231
52Asymmetry of the thorax (HP:0001555)2.09074761
53Papillary thyroid carcinoma (HP:0002895)2.07682616
54Neoplasm of the oral cavity (HP:0100649)2.07438058
55Heterotopia (HP:0002282)2.07427067
56Cutis marmorata (HP:0000965)2.06704125
57Neoplasm of striated muscle (HP:0009728)2.02040605
58Abnormal number of incisors (HP:0011064)1.99333148
59Hyperacusis (HP:0010780)1.99064218
60Myelodysplasia (HP:0002863)1.98903342
61Renal duplication (HP:0000075)1.98757806
62Transitional cell carcinoma of the bladder (HP:0006740)1.97492539
63Atresia of the external auditory canal (HP:0000413)1.97284462
64Sandal gap (HP:0001852)1.96712531
65Amaurosis fugax (HP:0100576)1.96437229
66Sloping forehead (HP:0000340)1.95225244
67Neoplasm of the colon (HP:0100273)1.94864586
68Aplasia involving forearm bones (HP:0009822)1.94645553
69Absent forearm bone (HP:0003953)1.94645553
70Overlapping toe (HP:0001845)1.91809264
71Cutaneous melanoma (HP:0012056)1.91773620
72Choanal atresia (HP:0000453)1.91267984
73Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.91012052
74Syringomyelia (HP:0003396)1.90954305
75Spinal cord lesions (HP:0100561)1.90954305
76Low anterior hairline (HP:0000294)1.90311968
77Pelvic girdle muscle weakness (HP:0003749)1.90017724
78Neoplasm of the pancreas (HP:0002894)1.89486749
79Skin tags (HP:0010609)1.89426770
80Rectal prolapse (HP:0002035)1.89153688
81Shallow orbits (HP:0000586)1.87125566
82Missing ribs (HP:0000921)1.86668288
83Skull defect (HP:0001362)1.85425269
84Neuroblastoma (HP:0003006)1.85075147
85Primitive neuroectodermal tumor (HP:0030065)1.85075147
86Neuroblastic tumors (HP:0004376)1.85075147
87Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.85075147
88Deep philtrum (HP:0002002)1.83035375
89Degeneration of anterior horn cells (HP:0002398)1.82497238
90Abnormality of the anterior horn cell (HP:0006802)1.82497238
91Thrombocytosis (HP:0001894)1.81733655
92Hematochezia (HP:0002573)1.81453691
93Broad palm (HP:0001169)1.81202307
94Cafe-au-lait spot (HP:0000957)1.80788027
95Uterine neoplasm (HP:0010784)1.79787951
96Aplasia/Hypoplasia of the uvula (HP:0010293)1.78901323
97Ankle contracture (HP:0006466)1.78707373
98Breast carcinoma (HP:0003002)1.78576918
99Abnormality of chromosome segregation (HP:0002916)1.78540960
100Meckel diverticulum (HP:0002245)1.77912885
101Carpal bone hypoplasia (HP:0001498)1.76556267
102Bladder neoplasm (HP:0009725)1.76190820
103Bladder carcinoma (HP:0002862)1.76190820
104Clubbing of toes (HP:0100760)1.76100474
105Abnormality of the calcaneus (HP:0008364)1.75992471
106Curly hair (HP:0002212)1.75293745
107Patellar aplasia (HP:0006443)1.74904386
108Cerebral aneurysm (HP:0004944)1.74413490
109Acute myeloid leukemia (HP:0004808)1.74088685
110Squamous cell carcinoma (HP:0002860)1.73875263
111Abnormality of the carotid arteries (HP:0005344)1.73525631
112Hepatoblastoma (HP:0002884)1.73210392
113Acute lymphatic leukemia (HP:0006721)1.72725354
114Broad thumb (HP:0011304)1.70860757
115Ankyloglossia (HP:0010296)1.70163205
116Ovarian neoplasm (HP:0100615)1.70097216
117Thyroid carcinoma (HP:0002890)1.69990644
118Bowel diverticulosis (HP:0005222)1.69982301
119Postnatal microcephaly (HP:0005484)1.69832948
120Abnormality of glycolysis (HP:0004366)1.69331921
121Horseshoe kidney (HP:0000085)1.69094276
122Arteriovenous malformation (HP:0100026)1.68832274
123Supernumerary ribs (HP:0005815)1.68598657
124T lymphocytopenia (HP:0005403)1.68310279
125Obsessive-compulsive behavior (HP:0000722)1.68235706
126Facial cleft (HP:0002006)1.68093672
127Abnormality of the hip-girdle musculature (HP:0001445)1.67740514
128Abnormality of the musculature of the pelvis (HP:0001469)1.67740514
129Bicuspid aortic valve (HP:0001647)1.67442415
130Intestinal polyp (HP:0005266)1.66902331
131Trigonocephaly (HP:0000243)1.66556606
132Anal stenosis (HP:0002025)1.65688393
133Preauricular skin tag (HP:0000384)1.65499064
134Abnormality of the peritoneum (HP:0002585)1.65332784
135Abnormality of the ileum (HP:0001549)1.64528244
136Aplasia/Hypoplasia of the patella (HP:0006498)1.64509378
137Neoplasm of the adrenal cortex (HP:0100641)1.64462239
138Protrusio acetabuli (HP:0003179)1.64391602
139Macroorchidism (HP:0000053)1.64312169
140Truncal obesity (HP:0001956)1.64283463
141Microglossia (HP:0000171)1.63341159
142Short thumb (HP:0009778)1.62783374
143Abnormality of the labia minora (HP:0012880)1.62763718
144Abnormal foot bone ossification (HP:0010675)1.62687243
145Aplasia/Hypoplasia of the sternum (HP:0006714)1.62665604
146Nervous tissue neoplasm (HP:0030060)1.62657028
147Neuroectodermal neoplasm (HP:0030061)1.62657028
148Neuroepithelial neoplasm (HP:0030063)1.62657028
149Blepharitis (HP:0000498)1.62625748
150Duodenal stenosis (HP:0100867)1.62371828
151Small intestinal stenosis (HP:0012848)1.62371828
15211 pairs of ribs (HP:0000878)1.62263547
153Limited elbow extension (HP:0001377)1.62199483
154Renovascular hypertension (HP:0100817)1.61977909
155Abnormality of oral frenula (HP:0000190)1.61673745
156Intestinal polyposis (HP:0200008)1.61301167
157Neoplasm of the small intestine (HP:0100833)1.60150965

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.08575649
2CDK123.38722656
3EEF2K3.30409561
4NEK22.73567332
5PKN22.67575241
6WEE12.65199185
7MAP3K102.58310558
8PBK2.36797446
9PASK1.98109115
10STK101.89628381
11RPS6KB21.88701088
12TAF11.85102960
13TSSK61.84056956
14SMG11.83218347
15SRPK11.82693983
16TTK1.81839404
17TGFBR11.81460772
18TRIB31.77020730
19SCYL21.75563487
20MKNK11.74446889
21BUB11.72233089
22ATR1.65515369
23LATS11.65495321
24BRD41.61089054
25CDK61.60536920
26CDK41.60018880
27MAP3K81.50549773
28RPS6KA41.47530272
29TRIM281.46084347
30ACVR1B1.43968638
31BRSK21.41274284
32AURKB1.38696830
33BCR1.36592576
34STK31.34254579
35EIF2AK11.34079570
36CDK71.33195456
37CHEK11.32338798
38LRRK21.30600284
39NEK11.29721149
40ALK1.29400710
41PLK11.29179149
42MAP4K11.23894554
43TTN1.22633571
44MKNK21.20494370
45STK41.20059249
46VRK21.19800387
47PTK61.19450191
48EIF2AK21.14828781
49PLK31.13918144
50MST41.13119054
51PAK41.12400680
52CHEK21.10867068
53MELK1.06730164
54MTOR1.06695511
55ATM1.04669695
56PIM11.04525099
57EPHA21.02384789
58PDGFRA1.01772382
59STK38L0.98226565
60DYRK30.97688455
61FGFR10.95247528
62FLT30.94369028
63PLK40.93455337
64CDK20.89351813
65FGFR30.89288029
66PAK20.81691096
67RIPK10.80393360
68ERBB40.78502157
69TLK10.78110561
70JAK30.77047975
71CDK90.73693676
72CAMK1G0.72772275
73LATS20.71704828
74NEK90.69442537
75GRK60.67235836
76CDK10.63874229
77MST1R0.63592000
78CHUK0.61410004
79MAP2K30.59565612
80CAMK1D0.59198794
81NME20.58030646
82CSNK1G10.56126085
83PNCK0.53975876
84YES10.53787893
85PRPF4B0.53609594
86PDGFRB0.53412905
87ERBB30.53092213
88MAP3K90.52893126
89PRKDC0.51998830
90ITK0.51985312
91CSNK1A1L0.51334462
92SIK30.50968888
93BRSK10.50478200
94BTK0.49340954
95MAP3K40.49163412
96STK240.48030703
97NEK60.47579470
98AURKA0.47517142
99TGFBR20.46292564
100CSNK1D0.46088428
101EIF2AK30.44325178
102CSF1R0.44253826
103ICK0.44198628
104FGFR20.43612273
105BMX0.43452184
106ZAP700.43301398
107KSR10.42824736
108CSNK1G30.42750668
109CSNK2A20.42620891
110ZAK0.42003790
111FGFR40.41802055
112STK160.41075383
113MAPK140.40146169
114VRK10.39819326
115BRAF0.39707740
116CSNK1E0.39295053
117MARK30.38673637
118TESK20.37880899
119CDK80.37085976
120AKT10.36010471
121CDK30.35874388
122RPS6KA50.35623274
123MAP3K140.35327689
124AKT20.34521539
125CDK180.34204907
126CSNK2A10.34074157
127CLK10.33974735
128MET0.33054602
129MAPK10.32645896
130RPS6KB10.32576660
131CCNB10.32399911
132RPS6KA10.31310406
133MAP3K30.30128250
134TBK10.29701509
135CDK11A0.29613903
136CDK150.29310440
137DYRK1B0.27821277

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.65403549
2Mismatch repair_Homo sapiens_hsa034303.18777313
3RNA transport_Homo sapiens_hsa030132.85055881
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.74288463
5* Spliceosome_Homo sapiens_hsa030402.73118421
6Cell cycle_Homo sapiens_hsa041102.73103435
7One carbon pool by folate_Homo sapiens_hsa006702.39883846
8Base excision repair_Homo sapiens_hsa034102.23675480
9mRNA surveillance pathway_Homo sapiens_hsa030152.12906993
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.09547019
11Nucleotide excision repair_Homo sapiens_hsa034202.01474958
12Non-homologous end-joining_Homo sapiens_hsa034501.97530498
13Homologous recombination_Homo sapiens_hsa034401.70786251
14Fanconi anemia pathway_Homo sapiens_hsa034601.68255750
15Systemic lupus erythematosus_Homo sapiens_hsa053221.66603927
16p53 signaling pathway_Homo sapiens_hsa041151.63721122
17Biosynthesis of amino acids_Homo sapiens_hsa012301.61718936
18Viral carcinogenesis_Homo sapiens_hsa052031.61598139
19Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.55903338
20MicroRNAs in cancer_Homo sapiens_hsa052061.53649537
21RNA degradation_Homo sapiens_hsa030181.49417360
22Small cell lung cancer_Homo sapiens_hsa052221.49230252
23Chronic myeloid leukemia_Homo sapiens_hsa052201.48939389
24Cysteine and methionine metabolism_Homo sapiens_hsa002701.48635232
25Antigen processing and presentation_Homo sapiens_hsa046121.44554898
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.36722546
27Herpes simplex infection_Homo sapiens_hsa051681.35859766
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.34300274
29HTLV-I infection_Homo sapiens_hsa051661.31628508
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.26907032
31Ribosome_Homo sapiens_hsa030101.23927297
32Epstein-Barr virus infection_Homo sapiens_hsa051691.21249008
33Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.21038847
34Transcriptional misregulation in cancer_Homo sapiens_hsa052021.20319599
35Adherens junction_Homo sapiens_hsa045201.16566004
36Colorectal cancer_Homo sapiens_hsa052101.16465919
37Thyroid cancer_Homo sapiens_hsa052161.07842844
38Carbon metabolism_Homo sapiens_hsa012001.05278052
39NF-kappa B signaling pathway_Homo sapiens_hsa040641.04668589
40mTOR signaling pathway_Homo sapiens_hsa041501.04580521
41Steroid biosynthesis_Homo sapiens_hsa001001.03493405
42Pancreatic cancer_Homo sapiens_hsa052121.02303741
43RNA polymerase_Homo sapiens_hsa030201.01971990
44Viral myocarditis_Homo sapiens_hsa054161.01310259
45Basal cell carcinoma_Homo sapiens_hsa052171.01224927
46Hepatitis B_Homo sapiens_hsa051611.00517193
47TGF-beta signaling pathway_Homo sapiens_hsa043500.99735518
48Hippo signaling pathway_Homo sapiens_hsa043900.99381618
49Basal transcription factors_Homo sapiens_hsa030220.97570074
50Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.97242773
51Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.95993832
52Pyrimidine metabolism_Homo sapiens_hsa002400.94662052
53Proteoglycans in cancer_Homo sapiens_hsa052050.94427534
54Measles_Homo sapiens_hsa051620.93809595
55Oocyte meiosis_Homo sapiens_hsa041140.93439655
56Pyruvate metabolism_Homo sapiens_hsa006200.92161121
57Legionellosis_Homo sapiens_hsa051340.91233240
58Non-small cell lung cancer_Homo sapiens_hsa052230.89664754
59Lysine degradation_Homo sapiens_hsa003100.89366995
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89292760
61Vitamin B6 metabolism_Homo sapiens_hsa007500.88214668
62Apoptosis_Homo sapiens_hsa042100.88158589
63Selenocompound metabolism_Homo sapiens_hsa004500.88025902
64Prostate cancer_Homo sapiens_hsa052150.87982854
65Notch signaling pathway_Homo sapiens_hsa043300.86766123
66Primary immunodeficiency_Homo sapiens_hsa053400.86064783
67Pentose phosphate pathway_Homo sapiens_hsa000300.83235121
68B cell receptor signaling pathway_Homo sapiens_hsa046620.82412494
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.81998129
70Bladder cancer_Homo sapiens_hsa052190.81870525
71Purine metabolism_Homo sapiens_hsa002300.81141980
72Acute myeloid leukemia_Homo sapiens_hsa052210.81021195
73T cell receptor signaling pathway_Homo sapiens_hsa046600.79500013
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.78623949
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77021169
76Toxoplasmosis_Homo sapiens_hsa051450.75896907
77Leukocyte transendothelial migration_Homo sapiens_hsa046700.75250004
78Endometrial cancer_Homo sapiens_hsa052130.75154365
79Shigellosis_Homo sapiens_hsa051310.74123427
80Pathways in cancer_Homo sapiens_hsa052000.73690803
81Protein export_Homo sapiens_hsa030600.73652901
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.73326899
83Leishmaniasis_Homo sapiens_hsa051400.72043323
84Influenza A_Homo sapiens_hsa051640.71679074
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69443510
86Focal adhesion_Homo sapiens_hsa045100.67787676
87Alcoholism_Homo sapiens_hsa050340.67523515
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67441199
89Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.67435189
90Propanoate metabolism_Homo sapiens_hsa006400.65109216
91N-Glycan biosynthesis_Homo sapiens_hsa005100.62931221
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62291347
93Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.62016081
94Hedgehog signaling pathway_Homo sapiens_hsa043400.61728156
95Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61692104
96TNF signaling pathway_Homo sapiens_hsa046680.61628008
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61132638
98HIF-1 signaling pathway_Homo sapiens_hsa040660.60533664
99FoxO signaling pathway_Homo sapiens_hsa040680.59029686
100Osteoclast differentiation_Homo sapiens_hsa043800.58418392
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.57545385
102Hematopoietic cell lineage_Homo sapiens_hsa046400.51152095
103RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48462845
104Jak-STAT signaling pathway_Homo sapiens_hsa046300.47674043
105Glioma_Homo sapiens_hsa052140.47237055
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.47115411
107PI3K-Akt signaling pathway_Homo sapiens_hsa041510.46959377
108ECM-receptor interaction_Homo sapiens_hsa045120.46315729
109Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46133647
110Melanoma_Homo sapiens_hsa052180.45428689
111Platelet activation_Homo sapiens_hsa046110.45336811
112Wnt signaling pathway_Homo sapiens_hsa043100.43685790
113Renal cell carcinoma_Homo sapiens_hsa052110.43594888
114Dorso-ventral axis formation_Homo sapiens_hsa043200.43011419
115Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.41350260
116Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.40902656
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.40676387
118Hepatitis C_Homo sapiens_hsa051600.40625087
119Intestinal immune network for IgA production_Homo sapiens_hsa046720.40616493
120Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40476886
121Proteasome_Homo sapiens_hsa030500.40388984
122Tight junction_Homo sapiens_hsa045300.40385251
123Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39820758
124ErbB signaling pathway_Homo sapiens_hsa040120.31279385
125Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29880165
126Inositol phosphate metabolism_Homo sapiens_hsa005620.27858506
127AMPK signaling pathway_Homo sapiens_hsa041520.23658260
128Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.22220664
129Fructose and mannose metabolism_Homo sapiens_hsa000510.20274504
130Prolactin signaling pathway_Homo sapiens_hsa049170.16025339

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