Rank | Gene Set | Z-score |
---|---|---|
1 | * actin-mediated cell contraction (GO:0070252) | 5.69563502 |
2 | cardiac muscle cell development (GO:0055013) | 4.76152986 |
3 | relaxation of cardiac muscle (GO:0055119) | 4.60063413 |
4 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.52883136 |
5 | cardiac cell development (GO:0055006) | 4.51158607 |
6 | actomyosin structure organization (GO:0031032) | 4.48817233 |
7 | retinal cone cell development (GO:0046549) | 4.43663742 |
8 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.40865006 |
9 | * regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.40366866 |
10 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 4.40308749 |
11 | cell communication by electrical coupling (GO:0010644) | 4.28242180 |
12 | response to inactivity (GO:0014854) | 4.21674709 |
13 | * actin filament-based movement (GO:0030048) | 4.21459417 |
14 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 4.19620293 |
15 | * regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 4.13338801 |
16 | * regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.10837589 |
17 | response to caffeine (GO:0031000) | 4.07601105 |
18 | relaxation of muscle (GO:0090075) | 4.02564238 |
19 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.97882119 |
20 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.94110729 |
21 | * regulation of skeletal muscle contraction (GO:0014819) | 3.91897351 |
22 | regulation of the force of heart contraction (GO:0002026) | 3.86251947 |
23 | detection of light stimulus involved in visual perception (GO:0050908) | 3.85439769 |
24 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.85439769 |
25 | rhodopsin mediated signaling pathway (GO:0016056) | 3.85050844 |
26 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.83815160 |
27 | * regulation of striated muscle contraction (GO:0006942) | 3.81458297 |
28 | muscle tissue morphogenesis (GO:0060415) | 3.78840487 |
29 | skeletal muscle contraction (GO:0003009) | 3.69466962 |
30 | relaxation of smooth muscle (GO:0044557) | 3.64402290 |
31 | * muscle contraction (GO:0006936) | 3.62429682 |
32 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.58036182 |
33 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.57621422 |
34 | regulation of membrane repolarization (GO:0060306) | 3.56318060 |
35 | eye photoreceptor cell development (GO:0042462) | 3.54608947 |
36 | photoreceptor cell development (GO:0042461) | 3.53854641 |
37 | cell communication involved in cardiac conduction (GO:0086065) | 3.53612548 |
38 | retinal rod cell development (GO:0046548) | 3.52990622 |
39 | photoreceptor cell maintenance (GO:0045494) | 3.51993032 |
40 | cellular potassium ion homeostasis (GO:0030007) | 3.47347580 |
41 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.46141329 |
42 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 3.44007777 |
43 | * muscle fiber development (GO:0048747) | 3.42245051 |
44 | * muscle system process (GO:0003012) | 3.42111822 |
45 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.38814756 |
46 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.37890767 |
47 | cardiac muscle adaptation (GO:0014887) | 3.37843047 |
48 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 3.37843047 |
49 | muscle hypertrophy in response to stress (GO:0003299) | 3.37843047 |
50 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.34880803 |
51 | regulation of cell communication by electrical coupling (GO:0010649) | 3.34876415 |
52 | fatty acid transmembrane transport (GO:1902001) | 3.34069332 |
53 | protein localization to synapse (GO:0035418) | 3.33244952 |
54 | cellular response to epinephrine stimulus (GO:0071872) | 3.28264791 |
55 | * regulation of cardiac muscle contraction (GO:0055117) | 3.26550409 |
56 | cardiac myofibril assembly (GO:0055003) | 3.26169465 |
57 | regulation of relaxation of muscle (GO:1901077) | 3.22996650 |
58 | striated muscle adaptation (GO:0014888) | 3.22485733 |
59 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.20057439 |
60 | * striated muscle cell development (GO:0055002) | 3.17212753 |
61 | atrial cardiac muscle cell action potential (GO:0086014) | 3.13090640 |
62 | cardiac chamber formation (GO:0003207) | 3.12667877 |
63 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 3.09385143 |
64 | positive regulation of cation channel activity (GO:2001259) | 3.08738896 |
65 | vocalization behavior (GO:0071625) | 3.08535051 |
66 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.07535391 |
67 | glutamate receptor signaling pathway (GO:0007215) | 3.06700141 |
68 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.04838505 |
69 | neuronal action potential propagation (GO:0019227) | 3.04484160 |
70 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.04393369 |
71 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.03710998 |
72 | cardiac muscle hypertrophy (GO:0003300) | 3.03537906 |
73 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.03144822 |
74 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.01674030 |
75 | skeletal muscle adaptation (GO:0043501) | 3.01178872 |
76 | * regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.00175884 |
77 | sarcomere organization (GO:0045214) | 2.98979316 |
78 | neuron cell-cell adhesion (GO:0007158) | 2.95329041 |
79 | innervation (GO:0060384) | 2.94466284 |
80 | * regulation of muscle system process (GO:0090257) | 2.94267852 |
81 | striated muscle hypertrophy (GO:0014897) | 2.94219107 |
82 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.94122073 |
83 | eye photoreceptor cell differentiation (GO:0001754) | 2.93298435 |
84 | photoreceptor cell differentiation (GO:0046530) | 2.93298435 |
85 | * regulation of heart rate (GO:0002027) | 2.92662006 |
86 | cardiac ventricle formation (GO:0003211) | 2.92637305 |
87 | interkinetic nuclear migration (GO:0022027) | 2.91999910 |
88 | response to muscle activity (GO:0014850) | 2.91287109 |
89 | regulation of actin filament-based movement (GO:1903115) | 2.91039320 |
90 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.88762536 |
91 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 2.88114371 |
92 | * cardiac muscle cell action potential (GO:0086001) | 2.88114371 |
93 | potassium ion import (GO:0010107) | 2.87129303 |
94 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.86233106 |
95 | regulation of skeletal muscle cell differentiation (GO:2001014) | 2.86208978 |
96 | detection of calcium ion (GO:0005513) | 2.85229785 |
97 | myofibril assembly (GO:0030239) | 2.84976612 |
98 | response to histamine (GO:0034776) | 2.84899573 |
99 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.84870700 |
100 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.84378859 |
101 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.82828023 |
102 | * regulation of muscle contraction (GO:0006937) | 2.79924186 |
103 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.78783587 |
104 | membrane hyperpolarization (GO:0060081) | 2.78603792 |
105 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 2.78418445 |
106 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 2.78418445 |
107 | * cardiac muscle contraction (GO:0060048) | 2.77583404 |
108 | synaptic transmission, glutamatergic (GO:0035249) | 2.76960003 |
109 | regulation of cardiac muscle cell differentiation (GO:2000725) | 2.76095563 |
110 | carnitine transmembrane transport (GO:1902603) | 2.75756419 |
111 | neuron-neuron synaptic transmission (GO:0007270) | 2.75715510 |
112 | membrane depolarization during action potential (GO:0086010) | 2.74449104 |
113 | regulation of ATPase activity (GO:0043462) | 2.74396500 |
114 | regulation of ATP catabolic process (GO:1903289) | 2.74396500 |
115 | * muscle cell development (GO:0055001) | 2.72936627 |
116 | negative regulation of protein localization to cell surface (GO:2000009) | 2.72674296 |
117 | presynaptic membrane assembly (GO:0097105) | 2.71704595 |
118 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.70267523 |
119 | synaptic vesicle exocytosis (GO:0016079) | 2.70148175 |
120 | retina layer formation (GO:0010842) | 2.69842383 |
121 | glutamate secretion (GO:0014047) | 2.69541196 |
122 | cGMP-mediated signaling (GO:0019934) | 2.68179746 |
123 | sodium ion export (GO:0071436) | 2.68107020 |
124 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.67749508 |
125 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.67461041 |
126 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.67166713 |
127 | * striated muscle contraction (GO:0006941) | 2.66455473 |
128 | potassium ion homeostasis (GO:0055075) | 2.64846799 |
129 | skeletal muscle fiber development (GO:0048741) | 2.62404698 |
130 | positive regulation of heart rate (GO:0010460) | 2.61912916 |
131 | regulation of cardioblast differentiation (GO:0051890) | 2.61795667 |
132 | cardiac conduction (GO:0061337) | 2.61710268 |
133 | locomotory exploration behavior (GO:0035641) | 2.61149808 |
134 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.60292531 |
135 | regulation of potassium ion transmembrane transport (GO:1901379) | 2.59978300 |
136 | * regulation of heart contraction (GO:0008016) | 2.59788360 |
137 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.59156905 |
138 | regulation of postsynaptic membrane potential (GO:0060078) | 2.57009115 |
139 | otic vesicle formation (GO:0030916) | 2.56487321 |
140 | response to epinephrine (GO:0071871) | 2.55093443 |
141 | L-amino acid import (GO:0043092) | 2.54870814 |
142 | detection of light stimulus (GO:0009583) | 2.53026719 |
143 | detection of visible light (GO:0009584) | 2.52529588 |
144 | adrenergic receptor signaling pathway (GO:0071875) | 2.51836271 |
145 | muscle hypertrophy (GO:0014896) | 2.51075271 |
146 | * regulation of calcium ion transmembrane transport (GO:1903169) | 2.50443992 |
147 | * regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.50443992 |
148 | phototransduction (GO:0007602) | 2.49949840 |
149 | adult heart development (GO:0007512) | 2.47588824 |
150 | regulation of potassium ion transmembrane transporter activity (GO:1901016) | 2.47186081 |
151 | calcium ion import (GO:0070509) | 2.46250756 |
152 | * actin-myosin filament sliding (GO:0033275) | 2.46079906 |
153 | * muscle filament sliding (GO:0030049) | 2.46079906 |
154 | regulation of sarcomere organization (GO:0060297) | 2.45688774 |
155 | carnitine shuttle (GO:0006853) | 2.42890662 |
156 | postsynaptic membrane organization (GO:0001941) | 2.42553111 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.96265930 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.78801606 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.52194198 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.40265448 |
5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.31489290 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.22819814 |
7 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.16795314 |
8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.12669169 |
9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.11943860 |
10 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.11847067 |
11 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.07744416 |
12 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.05996729 |
13 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.05996729 |
14 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.02312748 |
15 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.01607580 |
16 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.94936623 |
17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.91324088 |
18 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.89487228 |
19 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.89432590 |
20 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.88673063 |
21 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.84604252 |
22 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.83940370 |
23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.81218013 |
24 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.80572843 |
25 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.80228008 |
26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.75766838 |
27 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.75732408 |
28 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.75306147 |
29 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.74763160 |
30 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.74401317 |
31 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.72327012 |
32 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.72116582 |
33 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.68132787 |
34 | TP53_16413492_ChIP-PET_HCT116_Human | 1.66225809 |
35 | P300_19829295_ChIP-Seq_ESCs_Human | 1.64817529 |
36 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.64816939 |
37 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.60792565 |
38 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.55347801 |
39 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.53951576 |
40 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.46400161 |
41 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.46042907 |
42 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.42217789 |
43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.42155082 |
44 | VDR_22108803_ChIP-Seq_LS180_Human | 1.41751963 |
45 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.41308980 |
46 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.40608811 |
47 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.40185824 |
48 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.40167864 |
49 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.40167864 |
50 | * BCAT_22108803_ChIP-Seq_LS180_Human | 1.39460463 |
51 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.38515687 |
52 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.37027222 |
53 | AR_25329375_ChIP-Seq_VCAP_Human | 1.35348128 |
54 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.35159973 |
55 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.34507532 |
56 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.33228652 |
57 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.33208920 |
58 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.33009881 |
59 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.32328667 |
60 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.31324839 |
61 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.30813061 |
62 | * AR_19668381_ChIP-Seq_PC3_Human | 1.30392892 |
63 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.30054236 |
64 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.29946103 |
65 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29774464 |
66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.29063580 |
67 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29010696 |
68 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.27049291 |
69 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.24144807 |
70 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.23991494 |
71 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.23919486 |
72 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.22377838 |
73 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.21593707 |
74 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.20406254 |
75 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.19749598 |
76 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.19052277 |
77 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.18577006 |
78 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18577006 |
79 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.17682748 |
80 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.17281586 |
81 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16905259 |
82 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.16404784 |
83 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.15622930 |
84 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.15622930 |
85 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14827265 |
86 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.14544546 |
87 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.13752733 |
88 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.13555270 |
89 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.12500154 |
90 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.12398846 |
91 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.11918914 |
92 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.11828318 |
93 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.11687685 |
94 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.10781862 |
95 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.10655242 |
96 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.09666797 |
97 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.09518002 |
98 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.08709811 |
99 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.08482276 |
100 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.07872990 |
101 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.07797608 |
102 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.07590423 |
103 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.07395752 |
104 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.06734728 |
105 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.06708923 |
106 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.06428879 |
107 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.06316306 |
108 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.06253706 |
109 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.06214418 |
110 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.06112247 |
111 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.06064541 |
112 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.05898773 |
113 | CJUN_26792858_Chip-Seq_BT549_Human | 1.05798504 |
114 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.05606485 |
115 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.04587532 |
116 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04111290 |
117 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.03581951 |
118 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.02343878 |
119 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01925510 |
120 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.00493976 |
121 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.98334398 |
122 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.97661371 |
123 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.96775705 |
124 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.96663770 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MP0005551_abnormal_eye_electrophysiolog | 3.78261291 |
2 | * MP0004215_abnormal_myocardial_fiber | 3.18975315 |
3 | MP0002837_dystrophic_cardiac_calcinosis | 3.09476616 |
4 | * MP0000751_myopathy | 2.90733482 |
5 | MP0004859_abnormal_synaptic_plasticity | 2.61486572 |
6 | MP0006072_abnormal_retinal_apoptosis | 2.50860616 |
7 | MP0004084_abnormal_cardiac_muscle | 2.48123265 |
8 | MP0003011_delayed_dark_adaptation | 2.47478702 |
9 | MP0003646_muscle_fatigue | 2.44860014 |
10 | * MP0005253_abnormal_eye_physiology | 2.40845256 |
11 | MP0003880_abnormal_central_pattern | 2.39514507 |
12 | MP0004270_analgesia | 2.19969253 |
13 | MP0004036_abnormal_muscle_relaxation | 2.17920811 |
14 | MP0004233_abnormal_muscle_weight | 2.13786540 |
15 | MP0001486_abnormal_startle_reflex | 2.13191308 |
16 | MP0003136_yellow_coat_color | 2.09121438 |
17 | MP0003635_abnormal_synaptic_transmissio | 2.08002727 |
18 | * MP0000749_muscle_degeneration | 2.06141729 |
19 | * MP0003137_abnormal_impulse_conducting | 2.04248176 |
20 | MP0009046_muscle_twitch | 1.96358819 |
21 | * MP0005620_abnormal_muscle_contractility | 1.94926756 |
22 | MP0005423_abnormal_somatic_nervous | 1.83189045 |
23 | * MP0005330_cardiomyopathy | 1.81482459 |
24 | MP0009745_abnormal_behavioral_response | 1.76357289 |
25 | MP0004085_abnormal_heartbeat | 1.75030943 |
26 | MP0002063_abnormal_learning/memory/cond | 1.70649767 |
27 | MP0002064_seizures | 1.69234292 |
28 | MP0002972_abnormal_cardiac_muscle | 1.68652213 |
29 | MP0002272_abnormal_nervous_system | 1.66964598 |
30 | MP0004484_altered_response_of | 1.64579075 |
31 | MP0001502_abnormal_circadian_rhythm | 1.63264851 |
32 | MP0002572_abnormal_emotion/affect_behav | 1.62848573 |
33 | MP0005670_abnormal_white_adipose | 1.60866530 |
34 | MP0005646_abnormal_pituitary_gland | 1.60845294 |
35 | * MP0004087_abnormal_muscle_fiber | 1.58349769 |
36 | MP0001968_abnormal_touch/_nociception | 1.55759952 |
37 | MP0002734_abnormal_mechanical_nocicepti | 1.50426293 |
38 | MP0008775_abnormal_heart_ventricle | 1.49520563 |
39 | MP0002067_abnormal_sensory_capabilities | 1.47668093 |
40 | MP0000013_abnormal_adipose_tissue | 1.45593648 |
41 | * MP0002106_abnormal_muscle_physiology | 1.44289653 |
42 | * MP0005195_abnormal_posterior_eye | 1.44137678 |
43 | * MP0002127_abnormal_cardiovascular_syste | 1.42861753 |
44 | * MP0004145_abnormal_muscle_electrophysio | 1.41550356 |
45 | MP0002638_abnormal_pupillary_reflex | 1.39680302 |
46 | MP0009384_cardiac_valve_regurgitation | 1.38172208 |
47 | MP0009780_abnormal_chondrocyte_physiolo | 1.36417209 |
48 | MP0001984_abnormal_olfaction | 1.36204971 |
49 | * MP0002269_muscular_atrophy | 1.33525308 |
50 | MP0004130_abnormal_muscle_cell | 1.32408793 |
51 | MP0001440_abnormal_grooming_behavior | 1.28658245 |
52 | MP0002090_abnormal_vision | 1.28020171 |
53 | * MP0005369_muscle_phenotype | 1.27055770 |
54 | MP0005248_abnormal_Harderian_gland | 1.20825117 |
55 | MP0002229_neurodegeneration | 1.20554568 |
56 | MP0001501_abnormal_sleep_pattern | 1.17941679 |
57 | MP0000778_abnormal_nervous_system | 1.17848308 |
58 | MP0005171_absent_coat_pigmentation | 1.17156575 |
59 | MP0001324_abnormal_eye_pigmentation | 1.15788349 |
60 | MP0004272_abnormal_basement_membrane | 1.15092850 |
61 | * MP0002752_abnormal_somatic_nervous | 1.14703857 |
62 | * MP0002882_abnormal_neuron_morphology | 1.14079696 |
63 | MP0005386_behavior/neurological_phenoty | 1.13580480 |
64 | MP0004924_abnormal_behavior | 1.13580480 |
65 | MP0002557_abnormal_social/conspecific_i | 1.11410969 |
66 | MP0004858_abnormal_nervous_system | 1.11186259 |
67 | MP0002102_abnormal_ear_morphology | 1.11075441 |
68 | MP0001544_abnormal_cardiovascular_syste | 1.08914735 |
69 | MP0005385_cardiovascular_system_phenoty | 1.08914735 |
70 | MP0005623_abnormal_meninges_morphology | 1.08598222 |
71 | * MP0000759_abnormal_skeletal_muscle | 1.07810877 |
72 | MP0006138_congestive_heart_failure | 1.06042258 |
73 | MP0003937_abnormal_limbs/digits/tail_de | 1.05510652 |
74 | MP0004510_myositis | 1.04140159 |
75 | * MP0000750_abnormal_muscle_regeneration | 1.03897716 |
76 | MP0002736_abnormal_nociception_after | 1.03525872 |
77 | * MP0000747_muscle_weakness | 1.03237071 |
78 | MP0008569_lethality_at_weaning | 1.02258269 |
79 | MP0004885_abnormal_endolymph | 1.02257573 |
80 | * MP0010630_abnormal_cardiac_muscle | 1.01461230 |
81 | * MP0000733_abnormal_muscle_development | 0.99633588 |
82 | MP0010368_abnormal_lymphatic_system | 0.99567021 |
83 | MP0002332_abnormal_exercise_endurance | 0.99538768 |
84 | * MP0003950_abnormal_plasma_membrane | 0.97755075 |
85 | MP0002735_abnormal_chemical_nociception | 0.97698153 |
86 | * MP0005391_vision/eye_phenotype | 0.96781895 |
87 | MP0002184_abnormal_innervation | 0.93906616 |
88 | * MP0002108_abnormal_muscle_morphology | 0.93302196 |
89 | MP0006292_abnormal_olfactory_placode | 0.91828103 |
90 | * MP0003634_abnormal_glial_cell | 0.89883795 |
91 | MP0003633_abnormal_nervous_system | 0.89274246 |
92 | * MP0000266_abnormal_heart_morphology | 0.87157040 |
93 | MP0003221_abnormal_cardiomyocyte_apopto | 0.86769629 |
94 | MP0000579_abnormal_nail_morphology | 0.85983322 |
95 | MP0001188_hyperpigmentation | 0.84585497 |
96 | MP0005266_abnormal_metabolism | 0.83503352 |
97 | MP0001299_abnormal_eye_distance/ | 0.83301718 |
98 | * MP0002066_abnormal_motor_capabilities/c | 0.77603314 |
99 | MP0001970_abnormal_pain_threshold | 0.77554099 |
100 | MP0002234_abnormal_pharynx_morphology | 0.77445313 |
101 | MP0003690_abnormal_glial_cell | 0.77351465 |
102 | MP0010386_abnormal_urinary_bladder | 0.76682578 |
103 | MP0005595_abnormal_vascular_smooth | 0.76035525 |
104 | MP0003787_abnormal_imprinting | 0.75483846 |
105 | MP0006276_abnormal_autonomic_nervous | 0.74844893 |
106 | MP0000230_abnormal_systemic_arterial | 0.74120626 |
107 | MP0000955_abnormal_spinal_cord | 0.73872718 |
108 | MP0003631_nervous_system_phenotype | 0.73211588 |
109 | MP0005503_abnormal_tendon_morphology | 0.73136078 |
110 | MP0009250_abnormal_appendicular_skeleto | 0.72764897 |
111 | MP0005275_abnormal_skin_tensile | 0.72602823 |
112 | MP0005187_abnormal_penis_morphology | 0.70483003 |
113 | MP0000026_abnormal_inner_ear | 0.69057793 |
114 | MP0000372_irregular_coat_pigmentation | 0.68103219 |
115 | * MP0001963_abnormal_hearing_physiology | 0.68064541 |
116 | MP0000534_abnormal_ureter_morphology | 0.67965985 |
117 | MP0010030_abnormal_orbit_morphology | 0.67452261 |
118 | * MP0002128_abnormal_blood_circulation | 0.66057130 |
119 | MP0000383_abnormal_hair_follicle | 0.64984340 |
120 | MP0003385_abnormal_body_wall | 0.63189296 |
121 | MP0004043_abnormal_pH_regulation | 0.61833102 |
122 | MP0002971_abnormal_brown_adipose | 0.61051770 |
123 | MP0000427_abnormal_hair_cycle | 0.59072972 |
124 | MP0003935_abnormal_craniofacial_develop | 0.58985979 |
125 | MP0001879_abnormal_lymphatic_vessel | 0.58333498 |
126 | MP0000569_abnormal_digit_pigmentation | 0.57520003 |
127 | * MP0001661_extended_life_span | 0.54773444 |
128 | MP0000767_abnormal_smooth_muscle | 0.54769613 |
129 | MP0002822_catalepsy | 0.53631117 |
130 | MP0003890_abnormal_embryonic-extraembry | 0.53504470 |
131 | MP0000566_synostosis | 0.52901239 |
132 | MP0001529_abnormal_vocalization | 0.52343271 |
133 | MP0003879_abnormal_hair_cell | 0.52027603 |
134 | MP0003567_abnormal_fetal_cardiomyocyte | 0.51595277 |
135 | MP0003755_abnormal_palate_morphology | 0.50996141 |
136 | MP0001485_abnormal_pinna_reflex | 0.50151709 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nemaline bodies (HP:0003798) | 7.18378917 |
2 | Congenital stationary night blindness (HP:0007642) | 6.61236335 |
3 | Central scotoma (HP:0000603) | 5.15395450 |
4 | Sudden death (HP:0001699) | 4.75248002 |
5 | Scotoma (HP:0000575) | 4.30747233 |
6 | Bony spicule pigmentary retinopathy (HP:0007737) | 4.13772985 |
7 | Focal motor seizures (HP:0011153) | 3.98301960 |
8 | Exercise-induced myalgia (HP:0003738) | 3.95906243 |
9 | Atrial fibrillation (HP:0005110) | 3.88562561 |
10 | Calf muscle hypertrophy (HP:0008981) | 3.83848988 |
11 | Abnormality of macular pigmentation (HP:0008002) | 3.78704946 |
12 | Pigmentary retinal degeneration (HP:0001146) | 3.72228965 |
13 | Chorioretinal atrophy (HP:0000533) | 3.71701256 |
14 | Syncope (HP:0001279) | 3.70998778 |
15 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.68596454 |
16 | Primary atrial arrhythmia (HP:0001692) | 3.66856768 |
17 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.47437964 |
18 | Dyschromatopsia (HP:0007641) | 3.46548083 |
19 | Neck muscle weakness (HP:0000467) | 3.46320549 |
20 | Supraventricular tachycardia (HP:0004755) | 3.43851492 |
21 | Hip contracture (HP:0003273) | 3.40792649 |
22 | Subaortic stenosis (HP:0001682) | 3.38778053 |
23 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.38778053 |
24 | Epileptic encephalopathy (HP:0200134) | 3.38710537 |
25 | Supraventricular arrhythmia (HP:0005115) | 3.36183567 |
26 | Febrile seizures (HP:0002373) | 3.30204720 |
27 | Prolonged QT interval (HP:0001657) | 3.25351442 |
28 | * Abnormality of the calf musculature (HP:0001430) | 3.05950660 |
29 | * Dilated cardiomyopathy (HP:0001644) | 3.00849598 |
30 | Muscle fiber splitting (HP:0003555) | 2.93201369 |
31 | Aortic aneurysm (HP:0004942) | 2.89553493 |
32 | Decreased central vision (HP:0007663) | 2.85218750 |
33 | Myopathic facies (HP:0002058) | 2.84754966 |
34 | Attenuation of retinal blood vessels (HP:0007843) | 2.84179889 |
35 | Action tremor (HP:0002345) | 2.81427406 |
36 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.80950307 |
37 | Focal seizures (HP:0007359) | 2.74957920 |
38 | Areflexia of lower limbs (HP:0002522) | 2.72415075 |
39 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.71593870 |
40 | Exercise-induced muscle cramps (HP:0003710) | 2.70986415 |
41 | Absent phalangeal crease (HP:0006109) | 2.68336485 |
42 | Increased corneal curvature (HP:0100692) | 2.65585945 |
43 | Keratoconus (HP:0000563) | 2.65585945 |
44 | Ventricular tachycardia (HP:0004756) | 2.63756012 |
45 | Right ventricular cardiomyopathy (HP:0011663) | 2.63607090 |
46 | Hyporeflexia of lower limbs (HP:0002600) | 2.60451234 |
47 | Hyperventilation (HP:0002883) | 2.60275353 |
48 | Ulnar deviation of the wrist (HP:0003049) | 2.60134514 |
49 | EMG: neuropathic changes (HP:0003445) | 2.59329945 |
50 | Pendular nystagmus (HP:0012043) | 2.57385639 |
51 | Frequent falls (HP:0002359) | 2.54999282 |
52 | Abolished electroretinogram (ERG) (HP:0000550) | 2.53397210 |
53 | Ulnar claw (HP:0001178) | 2.50093212 |
54 | Progressive cerebellar ataxia (HP:0002073) | 2.48781526 |
55 | Dysdiadochokinesis (HP:0002075) | 2.47008838 |
56 | Asymmetric septal hypertrophy (HP:0001670) | 2.46322340 |
57 | Abnormal EKG (HP:0003115) | 2.45071012 |
58 | Rhabdomyolysis (HP:0003201) | 2.41992136 |
59 | Hyperkalemia (HP:0002153) | 2.41192230 |
60 | Neoplasm of the heart (HP:0100544) | 2.39907504 |
61 | Ventricular arrhythmia (HP:0004308) | 2.39031475 |
62 | Left ventricular hypertrophy (HP:0001712) | 2.38687127 |
63 | Steppage gait (HP:0003376) | 2.38597178 |
64 | EMG: myopathic abnormalities (HP:0003458) | 2.33650803 |
65 | Increased variability in muscle fiber diameter (HP:0003557) | 2.31966252 |
66 | Abnormal finger flexion creases (HP:0006143) | 2.31894385 |
67 | Calcaneovalgus deformity (HP:0001848) | 2.29627833 |
68 | Fetal akinesia sequence (HP:0001989) | 2.24196171 |
69 | Generalized muscle weakness (HP:0003324) | 2.24030641 |
70 | Difficulty running (HP:0009046) | 2.22022768 |
71 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.21797262 |
72 | Cone-rod dystrophy (HP:0000548) | 2.19971471 |
73 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.16294812 |
74 | Type II diabetes mellitus (HP:0005978) | 2.14615654 |
75 | Photophobia (HP:0000613) | 2.11955804 |
76 | Broad-based gait (HP:0002136) | 2.10677088 |
77 | Proximal amyotrophy (HP:0007126) | 2.05257702 |
78 | Severe visual impairment (HP:0001141) | 2.04615142 |
79 | Absence seizures (HP:0002121) | 2.04155453 |
80 | Myoglobinuria (HP:0002913) | 2.03967923 |
81 | Deformed tarsal bones (HP:0008119) | 2.03585424 |
82 | Malignant hyperthermia (HP:0002047) | 2.03481919 |
83 | Generalized tonic-clonic seizures (HP:0002069) | 2.03318705 |
84 | Dysmetric saccades (HP:0000641) | 2.02902222 |
85 | * Muscular dystrophy (HP:0003560) | 2.02255078 |
86 | Hypoplastic ischia (HP:0003175) | 2.00894369 |
87 | Scapular winging (HP:0003691) | 1.99652935 |
88 | Chronic hepatic failure (HP:0100626) | 1.98634418 |
89 | Dialeptic seizures (HP:0011146) | 1.97360424 |
90 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.96890547 |
91 | Bundle branch block (HP:0011710) | 1.96611443 |
92 | Type 1 muscle fiber predominance (HP:0003803) | 1.91857269 |
93 | Muscle fiber inclusion bodies (HP:0100299) | 1.90437390 |
94 | Retinitis pigmentosa (HP:0000510) | 1.87325177 |
95 | Macular degeneration (HP:0000608) | 1.87058764 |
96 | Heart block (HP:0012722) | 1.86855180 |
97 | * Lipoatrophy (HP:0100578) | 1.86811294 |
98 | Metatarsus adductus (HP:0001840) | 1.84743770 |
99 | Aplasia involving bones of the extremities (HP:0009825) | 1.84281395 |
100 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.84281395 |
101 | Aplasia of the phalanges of the hand (HP:0009802) | 1.84281395 |
102 | Round ear (HP:0100830) | 1.84250680 |
103 | Gaze-evoked nystagmus (HP:0000640) | 1.84212712 |
104 | Drooling (HP:0002307) | 1.83990365 |
105 | Excessive salivation (HP:0003781) | 1.83990365 |
106 | Septo-optic dysplasia (HP:0100842) | 1.83767352 |
107 | Abnormality of the ischium (HP:0003174) | 1.83493766 |
108 | Choroideremia (HP:0001139) | 1.83130558 |
109 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.83109301 |
110 | Gait imbalance (HP:0002141) | 1.83010610 |
111 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.82539216 |
112 | Hypoplastic left heart (HP:0004383) | 1.82447375 |
113 | Fair hair (HP:0002286) | 1.81962986 |
114 | Atonic seizures (HP:0010819) | 1.80063697 |
115 | * Gowers sign (HP:0003391) | 1.79902156 |
116 | Fatigable weakness (HP:0003473) | 1.79202963 |
117 | Abnormality of the neuromuscular junction (HP:0003398) | 1.79202963 |
118 | Increased connective tissue (HP:0009025) | 1.78431696 |
119 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.75951550 |
120 | Rimmed vacuoles (HP:0003805) | 1.74507078 |
121 | Congenital primary aphakia (HP:0007707) | 1.74279455 |
122 | Insidious onset (HP:0003587) | 1.73311482 |
123 | Termporal pattern (HP:0011008) | 1.73311482 |
124 | Limited hip movement (HP:0008800) | 1.73231423 |
125 | Myotonia (HP:0002486) | 1.72765907 |
126 | Genetic anticipation (HP:0003743) | 1.70479979 |
127 | Aortic dissection (HP:0002647) | 1.70298919 |
128 | Hemiparesis (HP:0001269) | 1.69726288 |
129 | Abnormal atrioventricular conduction (HP:0005150) | 1.69217138 |
130 | Popliteal pterygium (HP:0009756) | 1.68149641 |
131 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.67901253 |
132 | Ulnar deviation of finger (HP:0009465) | 1.67226305 |
133 | Toxemia of pregnancy (HP:0100603) | 1.66806927 |
134 | Distal arthrogryposis (HP:0005684) | 1.66233659 |
135 | Palpitations (HP:0001962) | 1.65598245 |
136 | Abnormality of the foot musculature (HP:0001436) | 1.65506740 |
137 | Atrioventricular block (HP:0001678) | 1.63321798 |
138 | Truncal ataxia (HP:0002078) | 1.62735843 |
139 | Myokymia (HP:0002411) | 1.61571050 |
140 | Visual hallucinations (HP:0002367) | 1.61322056 |
141 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 1.60827937 |
142 | Hammertoe (HP:0001765) | 1.60514417 |
143 | Long clavicles (HP:0000890) | 1.60510007 |
144 | Blue irides (HP:0000635) | 1.60428290 |
145 | Knee flexion contracture (HP:0006380) | 1.55449877 |
146 | Distal lower limb muscle weakness (HP:0009053) | 1.54001123 |
147 | Abnormality of potassium homeostasis (HP:0011042) | 1.53760063 |
148 | Preaxial foot polydactyly (HP:0001841) | 1.52441097 |
149 | Limb-girdle muscle atrophy (HP:0003797) | 1.50604218 |
150 | Ulnar deviation of the hand or of fingers of the hand (HP:0001193) | 1.48599709 |
151 | Ventricular fibrillation (HP:0001663) | 1.48280957 |
152 | Weak cry (HP:0001612) | 1.47819411 |
153 | Abnormal ciliary motility (HP:0012262) | 1.47528476 |
154 | Bicuspid aortic valve (HP:0001647) | 1.44172334 |
155 | Bulbar palsy (HP:0001283) | 1.43307195 |
156 | Hypoalphalipoproteinemia (HP:0003233) | 1.42702297 |
Rank | Gene Set | Z-score |
---|---|---|
1 | OBSCN | 4.18874000 |
2 | TNIK | 3.10218990 |
3 | EPHA4 | 2.91424957 |
4 | PHKG2 | 2.89302747 |
5 | PHKG1 | 2.89302747 |
6 | CASK | 2.75893960 |
7 | NTRK3 | 2.67614800 |
8 | INSRR | 2.50774145 |
9 | MAP3K4 | 2.36295064 |
10 | DMPK | 2.13419966 |
11 | LMTK2 | 1.96249150 |
12 | MAP2K7 | 1.87608668 |
13 | MUSK | 1.60069705 |
14 | AKT3 | 1.59604934 |
15 | PKN2 | 1.59508720 |
16 | MKNK2 | 1.59251299 |
17 | NTRK2 | 1.56440660 |
18 | PIK3CA | 1.55867675 |
19 | MAP2K4 | 1.54438425 |
20 | PINK1 | 1.50851454 |
21 | TTN | 1.45975167 |
22 | MYLK | 1.41713768 |
23 | PAK6 | 1.40082560 |
24 | ZAK | 1.37877348 |
25 | SGK2 | 1.37031409 |
26 | MARK1 | 1.36677684 |
27 | GRK1 | 1.33885871 |
28 | STK38 | 1.23121529 |
29 | CAMK2A | 1.17066596 |
30 | KSR1 | 1.17057615 |
31 | MAPK13 | 1.15736598 |
32 | SGK223 | 1.14944461 |
33 | SGK494 | 1.14944461 |
34 | CAMK1G | 1.13999586 |
35 | CAMK2D | 1.13639567 |
36 | MAP3K7 | 1.10704131 |
37 | SIK1 | 1.08007620 |
38 | BMPR1B | 1.06091867 |
39 | LATS1 | 1.04870790 |
40 | NEK9 | 1.04405538 |
41 | MAPK12 | 1.04201388 |
42 | SGK3 | 1.03591303 |
43 | PLK2 | 1.02453948 |
44 | GRK7 | 1.01709318 |
45 | MINK1 | 1.00510161 |
46 | TRPM7 | 0.99127752 |
47 | NEK1 | 0.97865897 |
48 | CDC42BPA | 0.97628024 |
49 | EPHA3 | 0.95882759 |
50 | ACVR1B | 0.95776187 |
51 | PAK3 | 0.94988666 |
52 | PDK3 | 0.92701163 |
53 | PDK4 | 0.92701163 |
54 | PRPF4B | 0.91316736 |
55 | DAPK2 | 0.85521617 |
56 | WNK1 | 0.84710552 |
57 | SGK1 | 0.83876195 |
58 | LIMK1 | 0.83778841 |
59 | PRKAA2 | 0.82776098 |
60 | PRKCG | 0.82635818 |
61 | STK39 | 0.81990718 |
62 | CAMK1D | 0.81531035 |
63 | NLK | 0.80922408 |
64 | MAPK7 | 0.79793252 |
65 | CDK3 | 0.79484164 |
66 | ADRBK1 | 0.78317720 |
67 | PTK2B | 0.77954455 |
68 | PNCK | 0.77454865 |
69 | MAP4K2 | 0.76446064 |
70 | FLT3 | 0.75967559 |
71 | PRKCE | 0.75633534 |
72 | STK38L | 0.75122168 |
73 | NTRK1 | 0.73484022 |
74 | CDK5 | 0.73420498 |
75 | PRKD3 | 0.72904095 |
76 | PRKAA1 | 0.72754037 |
77 | CAMK1 | 0.72428928 |
78 | ROCK1 | 0.72345103 |
79 | MAPKAPK3 | 0.71799966 |
80 | GRK5 | 0.68316264 |
81 | STK11 | 0.67902421 |
82 | MAP3K9 | 0.67900989 |
83 | CCNB1 | 0.67678573 |
84 | PKN1 | 0.66588065 |
85 | SIK3 | 0.66220830 |
86 | TIE1 | 0.65908767 |
87 | DYRK1A | 0.61586692 |
88 | MAP3K6 | 0.60818794 |
89 | CAMK4 | 0.60144433 |
90 | ERBB3 | 0.59539311 |
91 | PDK2 | 0.59329659 |
92 | PRKG1 | 0.58927599 |
93 | PRKACA | 0.57279238 |
94 | NUAK1 | 0.56243459 |
95 | RPS6KA3 | 0.55593640 |
96 | MARK2 | 0.55474928 |
97 | PRKACB | 0.52881662 |
98 | FGFR2 | 0.52388594 |
99 | BCR | 0.50830232 |
100 | NEK6 | 0.50378931 |
101 | FER | 0.50139641 |
102 | CAMK2B | 0.49427339 |
103 | FRK | 0.48674355 |
104 | STK24 | 0.48357145 |
105 | IRAK2 | 0.48237408 |
106 | CAMK2G | 0.47333053 |
107 | EPHB2 | 0.46632008 |
108 | RIPK1 | 0.44826501 |
109 | ICK | 0.44539132 |
110 | BRD4 | 0.44485808 |
111 | AKT2 | 0.44219434 |
112 | ROCK2 | 0.44124290 |
113 | WNK3 | 0.43695109 |
114 | STK3 | 0.43537446 |
115 | EEF2K | 0.43171346 |
116 | PRKACG | 0.42020901 |
117 | MAP2K1 | 0.41997114 |
118 | PIK3CG | 0.41758495 |
119 | OXSR1 | 0.41472213 |
120 | MELK | 0.41058120 |
121 | ERBB2 | 0.40049778 |
122 | PRKD1 | 0.37801900 |
123 | MAPK10 | 0.36748381 |
124 | MAPK4 | 0.34722756 |
125 | MET | 0.33227087 |
126 | WNK4 | 0.33111729 |
127 | TGFBR1 | 0.31399167 |
128 | RET | 0.30888968 |
129 | FGFR1 | 0.29553754 |
130 | LATS2 | 0.27298786 |
131 | ADRBK2 | 0.27136102 |
132 | MAPK15 | 0.27092461 |
133 | PAK2 | 0.25783400 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Phototransduction_Homo sapiens_hsa04744 | 5.13710437 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 3.12880106 |
3 | * Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.43782374 |
4 | * Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.29435856 |
5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.23644281 |
6 | * Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.23328989 |
7 | GABAergic synapse_Homo sapiens_hsa04727 | 2.15815241 |
8 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.15659042 |
9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.08189761 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.94997708 |
11 | Morphine addiction_Homo sapiens_hsa05032 | 1.87120252 |
12 | Insulin secretion_Homo sapiens_hsa04911 | 1.85417022 |
13 | Salivary secretion_Homo sapiens_hsa04970 | 1.76640812 |
14 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.72489580 |
15 | Circadian rhythm_Homo sapiens_hsa04710 | 1.70257842 |
16 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.67442464 |
17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.65647100 |
18 | Renin secretion_Homo sapiens_hsa04924 | 1.62027863 |
19 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.59997392 |
20 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.59078448 |
21 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.57697477 |
22 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.50240997 |
23 | Long-term potentiation_Homo sapiens_hsa04720 | 1.45569594 |
24 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.43716102 |
25 | Taste transduction_Homo sapiens_hsa04742 | 1.41880355 |
26 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.41877330 |
27 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.36977760 |
28 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.32650309 |
29 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.32583173 |
30 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.30774893 |
31 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.30259200 |
32 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.26192120 |
33 | ABC transporters_Homo sapiens_hsa02010 | 1.22088344 |
34 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.16960769 |
35 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.15670163 |
36 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.14313705 |
37 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.14265270 |
38 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.14088445 |
39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13132954 |
40 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.12822973 |
41 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.10731388 |
42 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.06651799 |
43 | Histidine metabolism_Homo sapiens_hsa00340 | 1.02885477 |
44 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.02675480 |
45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.01786411 |
46 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.00576916 |
47 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.99392344 |
48 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.97977637 |
49 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.97312989 |
50 | Long-term depression_Homo sapiens_hsa04730 | 0.95638473 |
51 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.94857887 |
52 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.93913008 |
53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.92840330 |
54 | Axon guidance_Homo sapiens_hsa04360 | 0.91869068 |
55 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.91749462 |
56 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.90209339 |
57 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.89224089 |
58 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.88804455 |
59 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.88039464 |
60 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.86929689 |
61 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.85488910 |
62 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.84145153 |
63 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.78212125 |
64 | Bile secretion_Homo sapiens_hsa04976 | 0.77245879 |
65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.76647612 |
66 | Gap junction_Homo sapiens_hsa04540 | 0.75122209 |
67 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.75096426 |
68 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.74129311 |
69 | Cocaine addiction_Homo sapiens_hsa05030 | 0.73375782 |
70 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.70062357 |
71 | Melanogenesis_Homo sapiens_hsa04916 | 0.69279240 |
72 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.65042346 |
73 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.64134851 |
74 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.64095533 |
75 | Lysine degradation_Homo sapiens_hsa00310 | 0.63605666 |
76 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.63063800 |
77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.63002743 |
78 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.62830140 |
79 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62297828 |
80 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.60415938 |
81 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.60399782 |
82 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.60027061 |
83 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.59808915 |
84 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.57899874 |
85 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.57882759 |
86 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.57131271 |
87 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.54437748 |
88 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53723398 |
89 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.53701352 |
90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.53541637 |
91 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.53301729 |
92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51704619 |
93 | Tight junction_Homo sapiens_hsa04530 | 0.51644681 |
94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.50374539 |
95 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.50259331 |
96 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49927427 |
97 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.49891185 |
98 | Peroxisome_Homo sapiens_hsa04146 | 0.49297145 |
99 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.48621344 |
100 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.48177177 |
101 | Focal adhesion_Homo sapiens_hsa04510 | 0.48043520 |
102 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.46772371 |
103 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.46624040 |
104 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.46293852 |
105 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.45791359 |
106 | Adherens junction_Homo sapiens_hsa04520 | 0.44817667 |
107 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.44647972 |
108 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.44375178 |
109 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44243582 |
110 | Retinol metabolism_Homo sapiens_hsa00830 | 0.43389550 |
111 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43087879 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.42944165 |
113 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.42726983 |
114 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.42494865 |
115 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.41607378 |
116 | Insulin resistance_Homo sapiens_hsa04931 | 0.41321106 |
117 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.41000238 |
118 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.40260474 |
119 | Mineral absorption_Homo sapiens_hsa04978 | 0.40123442 |
120 | Alzheimers disease_Homo sapiens_hsa05010 | 0.38817213 |
121 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.38566267 |
122 | Glioma_Homo sapiens_hsa05214 | 0.36057130 |
123 | Carbon metabolism_Homo sapiens_hsa01200 | 0.35630561 |
124 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.35504028 |
125 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.35040357 |
126 | Melanoma_Homo sapiens_hsa05218 | 0.34815889 |
127 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.33779741 |