DMRTC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptonemal complex assembly (GO:0007130)9.84687510
2sperm-egg recognition (GO:0035036)9.62637778
3axonemal dynein complex assembly (GO:0070286)9.56289634
4acrosome reaction (GO:0007340)9.46209406
5binding of sperm to zona pellucida (GO:0007339)9.09937042
6DNA methylation involved in gamete generation (GO:0043046)9.04846254
7DNA synthesis involved in DNA repair (GO:0000731)8.99729129
8spermatid development (GO:0007286)8.88939212
9acrosome assembly (GO:0001675)8.88004912
10epithelial cilium movement (GO:0003351)8.71341680
11cell-cell recognition (GO:0009988)8.61210304
12multicellular organism reproduction (GO:0032504)8.59833659
13motile cilium assembly (GO:0044458)8.51930233
14plasma membrane fusion (GO:0045026)8.42631146
15cell wall macromolecule catabolic process (GO:0016998)7.64647588
16cell wall macromolecule metabolic process (GO:0044036)7.64647588
17meiotic chromosome segregation (GO:0045132)7.52964561
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.49871368
19cilium movement (GO:0003341)7.44827966
20regulation of cilium movement (GO:0003352)7.41566143
21reproduction (GO:0000003)7.10050835
22histone H3-K9 demethylation (GO:0033169)7.07953042
23chromosome organization involved in meiosis (GO:0070192)6.99838734
24histone H3-K36 demethylation (GO:0070544)6.73863228
25* meiotic nuclear division (GO:0007126)6.40154623
26* male meiosis I (GO:0007141)6.16515334
27negative regulation of inclusion body assembly (GO:0090084)6.15164944
28single fertilization (GO:0007338)6.05962104
29spermatogenesis (GO:0007283)6.04202649
30male gamete generation (GO:0048232)6.02504179
31resolution of meiotic recombination intermediates (GO:0000712)5.85733883
32fertilization (GO:0009566)5.79648614
33sperm capacitation (GO:0048240)5.79036464
34regulation of meiosis I (GO:0060631)5.71403821
35germ cell development (GO:0007281)5.64198372
36gamete generation (GO:0007276)5.53747059
37meiotic cell cycle (GO:0051321)5.38577606
38gene silencing by RNA (GO:0031047)5.36742677
39positive regulation of meiosis (GO:0045836)5.29761384
40female gamete generation (GO:0007292)5.22586280
41microtubule depolymerization (GO:0007019)5.20071264
42* cellular process involved in reproduction in multicellular organism (GO:0022412)5.18561318
43* meiosis I (GO:0007127)5.00147704
44regulation of inclusion body assembly (GO:0090083)4.98067669
45positive regulation of meiotic cell cycle (GO:0051446)4.96308679
46negative regulation of gene silencing (GO:0060969)4.86190853
47ventricular system development (GO:0021591)4.82067844
48seminiferous tubule development (GO:0072520)4.74671234
49embryonic body morphogenesis (GO:0010172)4.66918763
50organic cation transport (GO:0015695)4.65995705
51regulation of microtubule-based movement (GO:0060632)4.54351178
52multicellular organismal reproductive process (GO:0048609)4.33060433
53regulation of DNA endoreduplication (GO:0032875)4.32441811
54regulation of meiotic cell cycle (GO:0051445)4.26342853
55* meiotic cell cycle process (GO:1903046)4.17794955
56left/right pattern formation (GO:0060972)4.15107756
57microtubule severing (GO:0051013)4.14972488
58genitalia morphogenesis (GO:0035112)4.13339045
59synapsis (GO:0007129)4.11538648
60DNA packaging (GO:0006323)4.09381743
61cell recognition (GO:0008037)4.01903378
62protein localization to cilium (GO:0061512)4.01642579
63positive regulation of response to oxidative stress (GO:1902884)4.00070758
64positive regulation of cellular response to oxidative stress (GO:1900409)4.00070758
65chromosome condensation (GO:0030261)3.99889752
66regulation of transcription from RNA polymerase I promoter (GO:0006356)3.99061185
67calcium ion-dependent exocytosis (GO:0017156)3.98915906
68chaperone-mediated protein complex assembly (GO:0051131)3.89515544
69gene silencing (GO:0016458)3.88103516
70nuclear pore complex assembly (GO:0051292)3.82160703
71DNA alkylation (GO:0006305)3.81799051
72DNA methylation (GO:0006306)3.81799051
73positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.72173845
74monoubiquitinated protein deubiquitination (GO:0035520)3.71038383
75body morphogenesis (GO:0010171)3.66899319
76negative regulation of organelle assembly (GO:1902116)3.64851853
77histone demethylation (GO:0016577)3.61308281
78histone lysine demethylation (GO:0070076)3.61120344
79histone H4-K12 acetylation (GO:0043983)3.59140246
80regulation of meiosis (GO:0040020)3.54659334
81signal complex assembly (GO:0007172)3.54574041
82protein polyglutamylation (GO:0018095)3.47541548
83multicellular organismal development (GO:0007275)3.44345139
84regulation of centriole replication (GO:0046599)3.42087717
85intraciliary transport (GO:0042073)3.41276316
86mitotic sister chromatid cohesion (GO:0007064)3.33105693
87attachment of spindle microtubules to kinetochore (GO:0008608)3.32657041
88protein dealkylation (GO:0008214)3.32564021
89protein demethylation (GO:0006482)3.32564021
90nuclear pore organization (GO:0006999)3.32350906
91interkinetic nuclear migration (GO:0022027)3.28647335
92sister chromatid cohesion (GO:0007062)3.26838948
93regulation of chromatin silencing (GO:0031935)3.25534883
94regulation of spindle checkpoint (GO:0090231)3.24488565
95DNA replication-dependent nucleosome organization (GO:0034723)3.20323060
96DNA replication-dependent nucleosome assembly (GO:0006335)3.20323060
97reproductive system development (GO:0061458)3.20228581
98chromosome organization (GO:0051276)3.16740975
99DNA biosynthetic process (GO:0071897)3.16739430
100axoneme assembly (GO:0035082)3.14909042
101DNA modification (GO:0006304)3.13953161
102heterochromatin organization (GO:0070828)3.13709690
103protein refolding (GO:0042026)3.11321235
104proteasome assembly (GO:0043248)3.11311751
105nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.08767207
106regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.07882977
107spermatid nucleus differentiation (GO:0007289)3.01876138
108glycerol ether metabolic process (GO:0006662)3.00431841
109microtubule-based movement (GO:0007018)2.93665311
110carnitine transport (GO:0015879)2.93456530
111amino-acid betaine transport (GO:0015838)2.93456530
112pore complex assembly (GO:0046931)2.93300466
113DNA methylation or demethylation (GO:0044728)2.92373111
114carnitine transmembrane transport (GO:1902603)2.91756137
115mitotic spindle assembly checkpoint (GO:0007094)2.89058097
116negative regulation of meiosis (GO:0045835)2.87316979
117protein localization to chromosome (GO:0034502)2.86723641
118translesion synthesis (GO:0019985)2.82594973
119spindle assembly checkpoint (GO:0071173)2.82297312
120growth hormone receptor signaling pathway (GO:0060396)2.81276393
121single strand break repair (GO:0000012)2.80736354
122histone exchange (GO:0043486)2.80005287
123ether metabolic process (GO:0018904)2.76014830
124histone H2A acetylation (GO:0043968)2.74623438
125negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.71538403
126negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.71538403
127negative regulation of mitotic sister chromatid segregation (GO:0033048)2.71538403
128negative regulation of mitotic sister chromatid separation (GO:2000816)2.71538403
129negative regulation of sister chromatid segregation (GO:0033046)2.71538403
130reciprocal meiotic recombination (GO:0007131)2.71468923
131reciprocal DNA recombination (GO:0035825)2.71468923
132regulation of protein polyubiquitination (GO:1902914)2.71239495
133mitotic spindle checkpoint (GO:0071174)2.70378016
134negative regulation of multicellular organism growth (GO:0040015)2.68192966
135* nuclear division (GO:0000280)2.67980526
136oogenesis (GO:0048477)2.67978235
137histone H4-K16 acetylation (GO:0043984)2.67700536
138cilium organization (GO:0044782)2.66722138
139centriole assembly (GO:0098534)2.66216097
140microtubule polymerization or depolymerization (GO:0031109)2.64577516
141oocyte development (GO:0048599)2.63463654
142regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:22.63189445
143negative regulation of DNA repair (GO:0045738)2.62774233
144glucosamine-containing compound catabolic process (GO:1901072)2.62628808
145centriole replication (GO:0007099)2.62508453
146negative regulation of chromosome segregation (GO:0051985)2.59554636
147regulation of mitotic sister chromatid separation (GO:0010965)2.58230364
148regulation of mitotic sister chromatid segregation (GO:0033047)2.58230364
149regulation of sister chromatid segregation (GO:0033045)2.58230364
150protein localization to chromosome, centromeric region (GO:0071459)2.56668550
151piRNA metabolic process (GO:0034587)13.5539217
152cilium or flagellum-dependent cell motility (GO:0001539)12.0740910
153fusion of sperm to egg plasma membrane (GO:0007342)11.1734649
154sperm motility (GO:0030317)11.0337529
155male meiosis (GO:0007140)10.2247968
156synaptonemal complex organization (GO:0070193)10.0621256

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.67276558
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.09298818
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.48419723
4IGF1R_20145208_ChIP-Seq_DFB_Human3.09541380
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.08722133
6* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.86015335
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.74831814
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.60224813
9GATA1_26923725_Chip-Seq_HPCs_Mouse2.42248469
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.39245193
11ER_23166858_ChIP-Seq_MCF-7_Human2.26597891
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.25484928
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.24273055
14BMI1_23680149_ChIP-Seq_NPCS_Mouse2.22444448
15TAF15_26573619_Chip-Seq_HEK293_Human2.12414027
16FUS_26573619_Chip-Seq_HEK293_Human2.07524525
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.01254323
18ELK4_26923725_Chip-Seq_MESODERM_Mouse2.00336437
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse12.7934383
20* BCAT_22108803_ChIP-Seq_LS180_Human1.89778131
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.84734741
22FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.76759640
23VDR_22108803_ChIP-Seq_LS180_Human1.76520511
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.75429389
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.71799618
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70469017
27ZNF274_21170338_ChIP-Seq_K562_Hela1.70155760
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69231947
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.68345997
30UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.63709501
31RBPJ_22232070_ChIP-Seq_NCS_Mouse1.62831629
32RUNX2_22187159_ChIP-Seq_PCA_Human1.62511282
33STAT3_23295773_ChIP-Seq_U87_Human1.62026884
34EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.59978047
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.53203880
36TCF4_23295773_ChIP-Seq_U87_Human1.52061235
37SMAD4_21741376_ChIP-Seq_EPCs_Human1.49860273
38WDR5_24793694_ChIP-Seq_LNCAP_Human1.49684126
39FLI1_27457419_Chip-Seq_LIVER_Mouse1.49415606
40ERA_21632823_ChIP-Seq_H3396_Human1.49159754
41KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.47982324
42FOXM1_23109430_ChIP-Seq_U2OS_Human1.47826174
43AR_25329375_ChIP-Seq_VCAP_Human1.47231234
44KLF5_20875108_ChIP-Seq_MESCs_Mouse1.46631377
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.43379700
46FOXA1_21572438_ChIP-Seq_LNCaP_Human1.41013422
47STAT1_17558387_ChIP-Seq_HELA_Human1.40580987
48PKCTHETA_26484144_Chip-Seq_BREAST_Human1.40328175
49GATA3_26560356_Chip-Seq_TH1_Human1.38667174
50SOX2_22085726_ChIP-Seq_NPCs_Mouse1.36450308
51TP53_22573176_ChIP-Seq_HFKS_Human1.33035712
52GATA3_21867929_ChIP-Seq_CD8_Mouse1.32837182
53PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.32271902
54FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.31378836
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.28599306
56SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.26900800
57TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.25962734
58VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.25877463
59IRF8_21731497_ChIP-ChIP_J774_Mouse1.25743245
60GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.25461295
61KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.25273636
62CBX2_27304074_Chip-Seq_ESCs_Mouse1.25128857
63TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.24888876
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23822936
65PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23495736
66RUNX1_26923725_Chip-Seq_HPCs_Mouse1.23449629
67YY1_22570637_ChIP-Seq_MALME-3M_Human1.23267443
68* SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.23151178
69TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21197276
70GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20190790
71GBX2_23144817_ChIP-Seq_PC3_Human1.20043133
72SMAD4_21799915_ChIP-Seq_A2780_Human1.19403959
73EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15766506
74P300_19829295_ChIP-Seq_ESCs_Human1.15591739
75E2F7_22180533_ChIP-Seq_HELA_Human1.15313442
76PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15294320
77EWS_26573619_Chip-Seq_HEK293_Human1.15125891
78TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human1.14438501
79SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14081230
80* FOXH1_21741376_ChIP-Seq_EPCs_Human1.13976830
81CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.13906488
82TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13836914
83RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13669092
84KAP1_22055183_ChIP-Seq_ESCs_Mouse1.13459129
85MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13161263
86LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.12473392
87PRDM14_20953172_ChIP-Seq_ESCs_Human1.12312875
88ETV1_20927104_ChIP-Seq_GIST48_Human1.11960200
89* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.11738740
90* FOXA1_25329375_ChIP-Seq_VCAP_Human1.11738740
91FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.10611306
92RXRA_24833708_ChIP-Seq_LIVER_Mouse1.09721589
93NCOR_22424771_ChIP-Seq_293T_Human1.08898176
94P53_21459846_ChIP-Seq_SAOS-2_Human1.08386780
95CBP_20019798_ChIP-Seq_JUKART_Human1.05414683
96IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.05414683
97TCF4_22108803_ChIP-Seq_LS180_Human1.04518025
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.04413827
99* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03943129
100CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03557306
101ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.03387660
102CDX2_22108803_ChIP-Seq_LS180_Human1.03186410
103MYC_19829295_ChIP-Seq_ESCs_Human1.03087439
104GATA3_21867929_ChIP-Seq_TH1_Mouse1.02548704
105ELF1_20517297_ChIP-Seq_JURKAT_Human1.02483585
106EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.02401479
107NFE2_27457419_Chip-Seq_LIVER_Mouse1.02130074
108NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.02077186
109RARA_24833708_ChIP-Seq_LIVER_Mouse1.01697540
110HOXB7_26014856_ChIP-Seq_BT474_Human1.01243954
111RAD21_21589869_ChIP-Seq_MESCs_Mouse1.01093710
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.00761209
113SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00223330
114PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00007857
115MYC_18940864_ChIP-ChIP_HL60_Human0.99692155
116CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99525830
117PHF8_20622853_ChIP-Seq_HELA_Human0.99438990
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99022030
119POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99022030
120SOX2_21211035_ChIP-Seq_LN229_Human0.98496780
121TAL1_26923725_Chip-Seq_HPCs_Mouse0.97488822
122SPI1_26923725_Chip-Seq_HPCs_Mouse0.97388789
123SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96875730
124PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.96223510
125MYCN_18555785_ChIP-Seq_MESCs_Mouse0.96122558
126AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.95836659
127MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.94807781
128PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93815632
129TBL1_22424771_ChIP-Seq_293T_Human0.93150026
130OCT4_20526341_ChIP-Seq_ESCs_Human0.92562044
131CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.92302603
132AUTS2_25519132_ChIP-Seq_293T-REX_Human0.92178723
133SMAD_19615063_ChIP-ChIP_OVARY_Human0.91040380
134ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90960445
135REST_21632747_ChIP-Seq_MESCs_Mouse0.90195737
136CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90146099
137FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.89204662
138TET1_21451524_ChIP-Seq_MESCs_Mouse0.88956012
139GF1_26923725_Chip-Seq_HPCs_Mouse0.88748589
140CTCF_20526341_ChIP-Seq_ESCs_Human0.88459087
141MYC_27129775_Chip-Seq_CORNEA_Mouse0.88278975
142SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88089853
143LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.88022683
144AR_20517297_ChIP-Seq_VCAP_Human0.86978109
145ERG_20517297_ChIP-Seq_VCAP_Human0.86751206
146NOTCH1_21737748_ChIP-Seq_TLL_Human0.86611439
147NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.86482211
148E2F1_20622854_ChIP-Seq_HELA_Human0.86000283
149OCT4_19829295_ChIP-Seq_ESCs_Human0.85984145
150ESET_19884257_ChIP-Seq_ESCs_Mouse0.85786758
151PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.85689408
152SMRT_27268052_Chip-Seq_Bcells_Human0.85084385
153RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84994051
154PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.84936390
155FLI1_21867929_ChIP-Seq_CD8_Mouse0.84722406
156* PHF8_20622854_ChIP-Seq_HELA_Human0.84531400
157SOX11_22085726_ChIP-Seq_ESNs_Mouse0.83415743
158PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.83127976
159RNF2_27304074_Chip-Seq_NSC_Mouse0.81967295
160STAT1_20625510_ChIP-Seq_HELA_Human0.80036663
161KDM2B_26808549_Chip-Seq_REH_Human0.79906429
162NFYB_21822215_ChIP-Seq_K562_Human0.79850397
163CTCF_26484167_Chip-Seq_Bcells_Mouse0.79749411
164STAT3_18555785_ChIP-Seq_MESCs_Mouse0.79331359
165SUZ12_27294783_Chip-Seq_NPCs_Mouse0.77621962
166FLI1_21867929_ChIP-Seq_TH2_Mouse0.77337504
167CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.76781021
168PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76404435
169GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75618082
170NANOG_20526341_ChIP-Seq_ESCs_Human0.75173089
171GATA1_19941827_ChIP-Seq_MEL86_Mouse0.74478437
172RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.73913387

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation7.54875469
2* MP0003698_abnormal_male_reproductive5.64709817
3* MP0001929_abnormal_gametogenesis5.46717612
4* MP0002210_abnormal_sex_determination4.19396183
5* MP0001145_abnormal_male_reproductive3.51111087
6MP0002653_abnormal_ependyma_morphology3.13738015
7* MP0002161_abnormal_fertility/fecundity3.11553500
8* MP0000653_abnormal_sex_gland3.04009291
9MP0003718_maternal_effect2.85374675
10MP0000678_abnormal_parathyroid_gland2.80007993
11MP0008057_abnormal_DNA_replication2.52123013
12MP0000015_abnormal_ear_pigmentation2.38539360
13MP0008995_early_reproductive_senescence2.17197273
14MP0010094_abnormal_chromosome_stability2.16306140
15MP0005174_abnormal_tail_pigmentation2.16280094
16MP0002160_abnormal_reproductive_system2.11670825
17MP0000383_abnormal_hair_follicle2.04913039
18MP0008058_abnormal_DNA_repair2.00148816
19MP0005410_abnormal_fertilization13.1430736
20MP0005623_abnormal_meninges_morphology1.93660017
21MP0005670_abnormal_white_adipose1.78466686
22MP0003786_premature_aging1.64799335
23MP0005409_darkened_coat_color1.64115892
24MP0010678_abnormal_skin_adnexa1.56339645
25MP0003646_muscle_fatigue1.50830483
26MP0003111_abnormal_nucleus_morphology1.42478933
27MP0008004_abnormal_stomach_pH1.41046899
28MP0003878_abnormal_ear_physiology1.35913010
29MP0005377_hearing/vestibular/ear_phenot1.35913010
30MP0008789_abnormal_olfactory_epithelium1.32780551
31MP0004233_abnormal_muscle_weight1.27928892
32MP0008007_abnormal_cellular_replicative1.26072917
33MP0003119_abnormal_digestive_system1.22037714
34MP0002282_abnormal_trachea_morphology1.21361226
35MP0010368_abnormal_lymphatic_system1.09492675
36MP0005389_reproductive_system_phenotype1.09440025
37MP0005647_abnormal_sex_gland1.06709341
38MP0003077_abnormal_cell_cycle1.03225575
39MP0002095_abnormal_skin_pigmentation1.02521335
40MP0003183_abnormal_peptide_metabolism0.99115827
41MP0003943_abnormal_hepatobiliary_system0.96583461
42MP0003252_abnormal_bile_duct0.92456377
43MP0006292_abnormal_olfactory_placode0.92029869
44MP0001986_abnormal_taste_sensitivity0.91358421
45MP0001730_embryonic_growth_arrest0.88549407
46MP0009278_abnormal_bone_marrow0.86480216
47MP0005310_abnormal_salivary_gland0.86153853
48MP0010307_abnormal_tumor_latency0.84829210
49MP0001188_hyperpigmentation0.84192133
50MP0005395_other_phenotype0.83878675
51MP0008260_abnormal_autophagy0.83556045
52MP0004957_abnormal_blastocyst_morpholog0.79142710
53MP0003115_abnormal_respiratory_system0.78955409
54MP0005499_abnormal_olfactory_system0.78081109
55MP0005394_taste/olfaction_phenotype0.78081109
56MP0000358_abnormal_cell_content/0.77061686
57MP0000371_diluted_coat_color0.76465393
58MP0001486_abnormal_startle_reflex0.76299730
59MP0003693_abnormal_embryo_hatching0.76016827
60MP0005551_abnormal_eye_electrophysiolog0.75722382
61MP0004808_abnormal_hematopoietic_stem0.75148827
62MP0000569_abnormal_digit_pigmentation0.73986518
63MP0001119_abnormal_female_reproductive0.72809709
64MP0003699_abnormal_female_reproductive0.72259198
65MP0001545_abnormal_hematopoietic_system0.68586590
66MP0005397_hematopoietic_system_phenotyp0.68586590
67MP0010386_abnormal_urinary_bladder0.68451035
68MP0003937_abnormal_limbs/digits/tail_de0.68242547
69MP0002249_abnormal_larynx_morphology0.66463446
70MP0002089_abnormal_postnatal_growth/wei0.66266646
71MP0001293_anophthalmia0.65387354
72MP0001984_abnormal_olfaction0.63538103
73MP0001919_abnormal_reproductive_system0.62506013
74MP0002084_abnormal_developmental_patter0.60046642
75MP0009046_muscle_twitch0.59788965
76MP0000647_abnormal_sebaceous_gland0.59678054
77MP0002138_abnormal_hepatobiliary_system0.59349495
78MP0000631_abnormal_neuroendocrine_gland0.56906846
79MP0005646_abnormal_pituitary_gland0.55374159
80MP0000313_abnormal_cell_death0.55080961
81MP0005380_embryogenesis_phenotype0.54627280
82MP0001672_abnormal_embryogenesis/_devel0.54627280
83MP0009745_abnormal_behavioral_response0.53674823
84MP0001727_abnormal_embryo_implantation0.52926501
85MP0001697_abnormal_embryo_size0.52041986
86MP0001661_extended_life_span0.51820029
87MP0005666_abnormal_adipose_tissue0.51749797
88MP0004197_abnormal_fetal_growth/weight/0.50906352
89MP0001765_abnormal_ion_homeostasis0.49414536
90MP0004019_abnormal_vitamin_homeostasis0.48672563
91MP0002269_muscular_atrophy0.47233148
92MP0001968_abnormal_touch/_nociception0.47010855
93MP0008932_abnormal_embryonic_tissue0.46531226
94MP0000350_abnormal_cell_proliferation0.45979176
95MP0003959_abnormal_lean_body0.45725178
96MP0002272_abnormal_nervous_system0.45372393
97MP0002085_abnormal_embryonic_tissue0.45109931
98MP0003984_embryonic_growth_retardation0.44756652
99MP0002075_abnormal_coat/hair_pigmentati0.44584393
100MP0003011_delayed_dark_adaptation0.44190498
101MP0005076_abnormal_cell_differentiation0.43294122
102MP0003950_abnormal_plasma_membrane0.43033304
103MP0001501_abnormal_sleep_pattern0.42840446
104MP0002080_prenatal_lethality0.42833681
105MP0002139_abnormal_hepatobiliary_system0.42096353
106MP0003861_abnormal_nervous_system0.42052450
107MP0003123_paternal_imprinting0.41828875
108MP0002088_abnormal_embryonic_growth/wei0.41744737
109MP0001849_ear_inflammation0.41609918
110MP0003879_abnormal_hair_cell0.40315752
111MP0003890_abnormal_embryonic-extraembry0.39543386
112MP0005645_abnormal_hypothalamus_physiol0.39078987
113MP0002067_abnormal_sensory_capabilities0.38700579
114MP0001666_abnormal_nutrient_absorption0.38517596
115MP0005391_vision/eye_phenotype0.38243430
116MP0004134_abnormal_chest_morphology0.38116801
117MP0001243_abnormal_dermal_layer0.37679474
118MP0004133_heterotaxia0.37404861
119MP0002092_abnormal_eye_morphology0.35786560
120MP0000778_abnormal_nervous_system0.35771929
121MP0000537_abnormal_urethra_morphology0.35519174
122MP0003942_abnormal_urinary_system0.35514176
123MP0000534_abnormal_ureter_morphology0.32961836
124MP0005253_abnormal_eye_physiology0.32927538
125MP0003045_fibrosis0.32481270
126MP0002234_abnormal_pharynx_morphology0.31118920
127MP0002086_abnormal_extraembryonic_tissu0.29219974
128MP0004036_abnormal_muscle_relaxation0.28267181
129MP0002971_abnormal_brown_adipose0.27897001
130MP0000751_myopathy0.27488589
131MP0006036_abnormal_mitochondrial_physio0.27382594
132MP0009115_abnormal_fat_cell0.26898238
133MP0001324_abnormal_eye_pigmentation0.26349661
134MP0002102_abnormal_ear_morphology0.25844617
135MP0001764_abnormal_homeostasis0.25702871
136MP0002152_abnormal_brain_morphology0.24548154
137MP0009672_abnormal_birth_weight0.24307868
138MP0008961_abnormal_basal_metabolism0.23949673
139MP0002928_abnormal_bile_duct0.23853366
140MP0006035_abnormal_mitochondrial_morpho0.22883034
141MP0003787_abnormal_imprinting0.22580663
142MP0002019_abnormal_tumor_incidence0.22228602
143* MP0003936_abnormal_reproductive_system0.20151874
144MP0000427_abnormal_hair_cycle0.19713368
145MP0003329_amyloid_beta_deposits0.18900059
146MP0009703_decreased_birth_body0.18617837
147MP0002697_abnormal_eye_size0.18230314
148MP0002108_abnormal_muscle_morphology0.18181173

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.58364818
2Abnormal respiratory motile cilium morphology (HP:0005938)8.35355367
3Abnormal respiratory epithelium morphology (HP:0012253)8.35355367
4Rhinitis (HP:0012384)7.55906481
5Chronic bronchitis (HP:0004469)6.65487924
6Abnormal ciliary motility (HP:0012262)6.64006182
7Infertility (HP:0000789)6.48655884
8Nasal polyposis (HP:0100582)6.13041724
9Horizontal nystagmus (HP:0000666)5.48299748
10Abnormality of the nasal mucosa (HP:0000433)5.00792280
11Genetic anticipation (HP:0003743)4.95551815
12Nephronophthisis (HP:0000090)4.64152044
13Volvulus (HP:0002580)4.40134324
14Shoulder girdle muscle weakness (HP:0003547)4.38583042
15Bronchiectasis (HP:0002110)4.36648254
16Gonadotropin excess (HP:0000837)4.33187073
17Oligodactyly (hands) (HP:0001180)4.32121051
18Bronchitis (HP:0012387)4.22216581
19Abnormality of the lower motor neuron (HP:0002366)4.15401152
20Abnormal spermatogenesis (HP:0008669)4.10939290
21Male infertility (HP:0003251)4.07259711
22Degeneration of the lateral corticospinal tracts (HP:0002314)3.91632311
23Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.91632311
24Osteomalacia (HP:0002749)3.58320761
25Progressive cerebellar ataxia (HP:0002073)3.55988194
26Azoospermia (HP:0000027)3.55987406
27Abnormality of the renal medulla (HP:0100957)3.49286240
28Action tremor (HP:0002345)3.44626705
29Abnormal protein glycosylation (HP:0012346)3.42884501
30Abnormal glycosylation (HP:0012345)3.42884501
31Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.42884501
32Abnormal protein N-linked glycosylation (HP:0012347)3.42884501
33Rimmed vacuoles (HP:0003805)3.41071901
34Type I transferrin isoform profile (HP:0003642)3.39865904
35Spontaneous abortion (HP:0005268)3.29469551
36Recurrent otitis media (HP:0000403)3.12476748
37Impulsivity (HP:0100710)3.09744580
38Amyotrophic lateral sclerosis (HP:0007354)3.05989475
39Facial hemangioma (HP:0000329)3.03923019
40Abnormality of DNA repair (HP:0003254)3.01017546
41Tubulointerstitial nephritis (HP:0001970)2.99819127
42Lip pit (HP:0100267)2.98964131
43Urinary bladder sphincter dysfunction (HP:0002839)2.97039732
44Oligodactyly (HP:0012165)2.95964857
45Abnormality of the corticospinal tract (HP:0002492)2.87913477
46Chromosomal breakage induced by crosslinking agents (HP:0003221)2.84406039
47Tubular atrophy (HP:0000092)2.79651307
48Dysmetric saccades (HP:0000641)2.79416730
49Impaired vibratory sensation (HP:0002495)2.77793563
50Chromsome breakage (HP:0040012)2.77766669
51Fibular hypoplasia (HP:0003038)2.77139860
52Recurrent sinusitis (HP:0011108)2.71350750
53Non-midline cleft lip (HP:0100335)2.64558574
54Severe visual impairment (HP:0001141)2.61745551
55Hypoplastic iliac wings (HP:0002866)2.60120096
56Recurrent bronchitis (HP:0002837)2.60035685
57Gaze-evoked nystagmus (HP:0000640)2.52394570
58Abnormality of midbrain morphology (HP:0002418)2.51533949
59Molar tooth sign on MRI (HP:0002419)2.51533949
60Dysdiadochokinesis (HP:0002075)2.49381165
61Capillary hemangiomas (HP:0005306)2.49017410
62Truncal obesity (HP:0001956)2.44822868
63Attenuation of retinal blood vessels (HP:0007843)2.44105210
64Tubulointerstitial abnormality (HP:0001969)2.42263779
65Slow saccadic eye movements (HP:0000514)2.40339724
66Abnormality of chromosome segregation (HP:0002916)2.38667662
67Large hands (HP:0001176)2.33219457
68Scotoma (HP:0000575)2.28950883
69Short nail (HP:0001799)2.26490253
70Widely spaced teeth (HP:0000687)2.26193051
71Hyperkalemia (HP:0002153)2.25609765
72Postaxial foot polydactyly (HP:0001830)2.22086279
73Fair hair (HP:0002286)2.20721194
74Hypoplasia of the capital femoral epiphysis (HP:0003090)2.20261225
75Supernumerary spleens (HP:0009799)2.19368721
76Impaired vibration sensation in the lower limbs (HP:0002166)2.16788554
77Impaired proprioception (HP:0010831)2.15832467
7811 pairs of ribs (HP:0000878)2.14252868
79Stage 5 chronic kidney disease (HP:0003774)2.14143133
80Short ribs (HP:0000773)2.13417540
81Upper motor neuron abnormality (HP:0002127)2.13293604
82Degeneration of anterior horn cells (HP:0002398)2.12553389
83Abnormality of the anterior horn cell (HP:0006802)2.12553389
84Absent speech (HP:0001344)2.11700909
85Metaphyseal cupping (HP:0003021)2.09384629
86Heterotopia (HP:0002282)2.08135667
87Small intestinal stenosis (HP:0012848)2.07373427
88Duodenal stenosis (HP:0100867)2.07373427
89Medial flaring of the eyebrow (HP:0010747)2.07208895
90Increased nuchal translucency (HP:0010880)2.05759006
91Proximal tubulopathy (HP:0000114)2.04389783
92Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.4787733
93Dynein arm defect of respiratory motile cilia (HP:0012255)11.8673063
94Absent/shortened dynein arms (HP:0200106)11.8673063
95Bundle branch block (HP:0011710)1.99961885
96Spastic tetraparesis (HP:0001285)1.96543305
97Nephroblastoma (Wilms tumor) (HP:0002667)1.92790460
98Preaxial hand polydactyly (HP:0001177)1.92611773
99Aplasia/Hypoplasia of the sternum (HP:0006714)1.91235932
100Facial cleft (HP:0002006)1.88558789
101Postural instability (HP:0002172)1.86712445
102Embryonal renal neoplasm (HP:0011794)1.86248766
103Resting tremor (HP:0002322)1.85047874
104Rhabdomyosarcoma (HP:0002859)1.84742484
105Oculomotor apraxia (HP:0000657)1.84535658
106Tubulointerstitial fibrosis (HP:0005576)1.82538326
107Menstrual irregularities (HP:0000858)1.81707111
108Congenital hepatic fibrosis (HP:0002612)1.80618798
109Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.80429682
110Renal dysplasia (HP:0000110)1.80281258
111Abnormal lung lobation (HP:0002101)1.80156673
112Aplasia/Hypoplasia of the fibula (HP:0006492)1.78449788
113Multicystic kidney dysplasia (HP:0000003)1.78185600
114Microglossia (HP:0000171)1.75734492
115Abnormality of dentin (HP:0010299)1.75061657
116Hyperpituitarism (HP:0010514)1.74248978
117Selective tooth agenesis (HP:0001592)1.73946598
118Urinary urgency (HP:0000012)1.72686407
119Absent frontal sinuses (HP:0002688)1.71903558
120Abnormality of the duodenum (HP:0002246)1.71266138
121Abnormality of the renal collecting system (HP:0004742)1.70686860
122Papillary thyroid carcinoma (HP:0002895)1.70537374
123Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.70275179
124Absent epiphyses (HP:0010577)1.70275179
125Abnormality of the renal cortex (HP:0011035)1.70233424
126Bell-shaped thorax (HP:0001591)1.69621550
127Abnormality of macular pigmentation (HP:0008002)1.67326756
128Type II lissencephaly (HP:0007260)1.67269217
129Polydipsia (HP:0001959)1.66908832
130Abnormal drinking behavior (HP:0030082)1.66908832
131Anterior segment dysgenesis (HP:0007700)1.65166953
132Hyperventilation (HP:0002883)1.63277354
133Limb ataxia (HP:0002070)1.62710410
134Short thorax (HP:0010306)1.61489844
135Limb-girdle muscle weakness (HP:0003325)1.61025149
136Retinitis pigmentosa (HP:0000510)1.59644892
137Median cleft lip (HP:0000161)1.57514947
138Cholecystitis (HP:0001082)1.57064862
139Abnormal gallbladder physiology (HP:0012438)1.57064862
140Postaxial hand polydactyly (HP:0001162)1.55251683
141J-shaped sella turcica (HP:0002680)1.53721472
142Deformed sella turcica (HP:0002681)1.51239993
143Renovascular hypertension (HP:0100817)1.47254062
144Abnormality of permanent molar morphology (HP:0011071)1.46461208
145Abnormality of the dental root (HP:0006486)1.46461208
146Taurodontia (HP:0000679)1.46461208
147Abnormal biliary tract physiology (HP:0012439)1.46156428
148Bile duct proliferation (HP:0001408)1.46156428
149Broad distal phalanx of finger (HP:0009836)1.42178503
150Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.39168811
151Hand muscle atrophy (HP:0009130)1.38271261
152Abnormality of ocular smooth pursuit (HP:0000617)1.38003953
153Abnormality of molar morphology (HP:0011070)1.36314819
154Abnormality of molar (HP:0011077)1.36314819
155Cystic liver disease (HP:0006706)1.36257246
156Atrophy/Degeneration involving motor neurons (HP:0007373)1.33064959
157Ectopic kidney (HP:0000086)1.32506126
158Missing ribs (HP:0000921)1.31890164
159Sloping forehead (HP:0000340)1.31615528
160Breast carcinoma (HP:0003002)1.30297125
161Abnormality of renal excretion (HP:0011036)1.30024553
162Decreased motor nerve conduction velocity (HP:0003431)1.29863990
163Difficulty climbing stairs (HP:0003551)1.29633169
164Abnormality of the dental pulp (HP:0006479)1.29324274
165Chronic sinusitis (HP:0011109)1.29313708
166Dyschromatopsia (HP:0007641)1.27800112
167Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.27330091
168Choroideremia (HP:0001139)1.25600936
169Hyporeflexia of lower limbs (HP:0002600)1.25373901
170Pachygyria (HP:0001302)1.25186928
171Short femoral neck (HP:0100864)1.24692816
172Cerebellar dysplasia (HP:0007033)1.22013589
173Aplasia/Hypoplasia of the tongue (HP:0010295)1.20619523

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.18942352
2PDK48.18942352
3CDK197.08920109
4TESK15.44087231
5PDK25.27211249
6PRKD34.33324282
7ICK4.14295533
8OXSR13.46010850
9CSF1R2.51704914
10PNCK2.41676761
11BMX2.34363724
12NEK22.32629082
13FGR2.30078078
14PTK2B2.21016894
15WNK42.19394041
16STK391.90084289
17MST1R1.86393888
18CDC71.75364014
19MAP3K91.69168191
20PLK21.60733314
21FRK1.54674998
22STK381.44039930
23CDK121.34515310
24DYRK1B1.32097818
25TYRO31.26724802
26WEE11.25177558
27RET1.21339268
28CASK1.20822768
29WNK11.17954473
30MAPK151.14482549
31TTK1.11877117
32STK31.07252328
33PASK1.05629340
34DYRK30.99263768
35NEK90.98919780
36NEK60.94442121
37PTK20.91120775
38MAP3K130.90597251
39ATR0.86042379
40ARAF0.83751690
41PRKCI0.83517027
42CCNB10.77744784
43PDK10.77359400
44CHEK10.77304071
45EEF2K0.77194221
46CHEK20.72220382
47BRAF0.69759309
48KSR10.69647132
49MARK30.68262940
50PLK10.61629282
51MAP3K50.61023554
52MAPK130.60697033
53MTOR0.59374364
54ATM0.57874693
55STK160.57482643
56TNK20.56357184
57CAMK1G0.55165863
58TAOK30.54225455
59MAP3K20.52947014
60SGK10.52452605
61PLK40.50771600
62ADRBK10.50079111
63KSR20.48281627
64TESK20.45522750
65BMPR1B0.45240960
66TAF10.45018555
67NEK10.43733853
68PINK10.42359058
69PAK40.40093247
70STK38L0.38094991
71CAMK10.38052777
72ACVR1B0.37971908
73TAOK20.36827472
74MELK0.36229734
75MAP3K100.35794866
76PAK20.35541606
77PAK10.34739744
78DYRK1A0.34398339
79CDK70.33927320
80ROCK10.33650508
81PBK0.33551304
82STK240.30355848
83BRSK20.30059055
84GRK10.29332253
85CDK50.29174121
86IGF1R0.28699838
87IRAK10.28583810
88BUB10.28337571
89PRPF4B0.28188728
90RAF10.27811681
91CDK20.26282510
92EPHA40.25967912
93ZAK0.25636285
94NUAK10.25464428
95PDPK10.25360142
96NTRK20.25056642
97WNK30.25024227
98PRKG10.24950718
99MAP2K20.24859827
100LMTK20.23791480
101CDK40.22617470
102CDK10.22195442
103RPS6KB10.22147416
104MAP3K120.21111070
105MUSK0.20920898
106MOS0.20907131
107PRKAA10.20621817
108NTRK30.20289776
109MAP3K70.18402130
110CDK30.18164737
111AURKB0.15226927
112BRSK10.14656249
113GSK3B0.13660766
114PRKDC0.13476204
115TAOK10.12935210
116CSNK1D0.12314807
117BRD40.12164139
118CSNK2A10.11814153
119SRPK10.11784520
120PRKCG0.11333189
121MAP3K40.11326653
122PDGFRB0.11319230
123MAP2K60.11088784
124PIM10.10838895
125AURKA0.10560798
126CDK60.10480427
127CSNK2A20.10023177
128CLK10.09962848
129RPS6KA10.09819351
130MARK20.09425788
131MAPK80.09139435
132CDK90.07633066
133PAK60.07322685
134YES10.07141149
135STK110.07081342
136STK40.04948957
137MAPK10.04775356
138CSNK1E0.04741552
139EGFR0.04539979
140CAMKK10.03954884
141MAPK100.03614383
142TRIB30.03125403
143EIF2AK10.02657302
144STK100.02191152
145PRKACB0.02076951
146PRKCZ0.01581677
147MET0.01439704
148CDK150.01417496
149IRAK20.01006055
150MAPK140.00998099
151MAPKAPK30.00795143
152RPS6KA3-0.0101480
153CDK18-0.0072837
154CDK11A-0.0047440

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.72358289
2Pyruvate metabolism_Homo sapiens_hsa006203.56172449
3Dorso-ventral axis formation_Homo sapiens_hsa043203.42065849
4Vitamin B6 metabolism_Homo sapiens_hsa007503.38984038
5Basal transcription factors_Homo sapiens_hsa030223.29076095
6Fatty acid biosynthesis_Homo sapiens_hsa000613.27604976
7Fanconi anemia pathway_Homo sapiens_hsa034603.02950902
8Selenocompound metabolism_Homo sapiens_hsa004502.92082739
9Regulation of autophagy_Homo sapiens_hsa041402.69598152
10RNA transport_Homo sapiens_hsa030132.50990944
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.50658967
12Glucagon signaling pathway_Homo sapiens_hsa049222.43212076
13Linoleic acid metabolism_Homo sapiens_hsa005912.42028302
14mRNA surveillance pathway_Homo sapiens_hsa030152.41531836
15Oocyte meiosis_Homo sapiens_hsa041142.36992933
16Propanoate metabolism_Homo sapiens_hsa006402.32699995
17Primary bile acid biosynthesis_Homo sapiens_hsa001202.11761543
18Pentose phosphate pathway_Homo sapiens_hsa000302.07633790
19Homologous recombination_Homo sapiens_hsa034401.94040416
20Phototransduction_Homo sapiens_hsa047441.92047925
21Glycerolipid metabolism_Homo sapiens_hsa005611.89889157
22Sulfur relay system_Homo sapiens_hsa041221.88160077
23Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.74338999
24DNA replication_Homo sapiens_hsa030301.73825102
25Circadian rhythm_Homo sapiens_hsa047101.65153697
26Huntingtons disease_Homo sapiens_hsa050161.56267778
27Carbohydrate digestion and absorption_Homo sapiens_hsa049731.52148271
28Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.51854175
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.50862569
30Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.46077116
31Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.44209523
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.41885476
33Glycerophospholipid metabolism_Homo sapiens_hsa005641.40498576
34Antigen processing and presentation_Homo sapiens_hsa046121.37192845
35ErbB signaling pathway_Homo sapiens_hsa040121.36936494
36Cell cycle_Homo sapiens_hsa041101.36248807
37Mismatch repair_Homo sapiens_hsa034301.34687941
38Olfactory transduction_Homo sapiens_hsa047401.30937255
39Fructose and mannose metabolism_Homo sapiens_hsa000511.30487789
40Carbon metabolism_Homo sapiens_hsa012001.29814437
41PPAR signaling pathway_Homo sapiens_hsa033201.21455234
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.20344965
43Amphetamine addiction_Homo sapiens_hsa050311.13786857
44Spliceosome_Homo sapiens_hsa030401.11678094
45Fat digestion and absorption_Homo sapiens_hsa049751.09751268
46Purine metabolism_Homo sapiens_hsa002301.08452735
47Biosynthesis of amino acids_Homo sapiens_hsa012301.07392510
48Nucleotide excision repair_Homo sapiens_hsa034201.05548871
49mTOR signaling pathway_Homo sapiens_hsa041501.05410367
50RNA degradation_Homo sapiens_hsa030180.99697979
51Choline metabolism in cancer_Homo sapiens_hsa052310.97898497
52Base excision repair_Homo sapiens_hsa034100.97690485
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97201493
54SNARE interactions in vesicular transport_Homo sapiens_hsa041300.96365873
55Ether lipid metabolism_Homo sapiens_hsa005650.96177787
56Fatty acid metabolism_Homo sapiens_hsa012120.95628894
57Hedgehog signaling pathway_Homo sapiens_hsa043400.93249058
58Cardiac muscle contraction_Homo sapiens_hsa042600.90203391
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.88926897
60Retinol metabolism_Homo sapiens_hsa008300.85224695
61Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.84554641
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84127995
63Taste transduction_Homo sapiens_hsa047420.82137648
64RNA polymerase_Homo sapiens_hsa030200.80596797
65Pyrimidine metabolism_Homo sapiens_hsa002400.79957747
66Small cell lung cancer_Homo sapiens_hsa052220.79539392
67Nicotine addiction_Homo sapiens_hsa050330.79341375
68Non-homologous end-joining_Homo sapiens_hsa034500.79181574
69Renin secretion_Homo sapiens_hsa049240.78790253
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77329472
71Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.76001187
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.74195315
73NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73627438
74Fatty acid degradation_Homo sapiens_hsa000710.71482824
75Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67535289
76Mineral absorption_Homo sapiens_hsa049780.66553638
77Caffeine metabolism_Homo sapiens_hsa002320.66137840
78Legionellosis_Homo sapiens_hsa051340.64198491
79Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.63874775
80Estrogen signaling pathway_Homo sapiens_hsa049150.63629977
81Systemic lupus erythematosus_Homo sapiens_hsa053220.63054210
82TGF-beta signaling pathway_Homo sapiens_hsa043500.61566426
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.60767294
84Glutathione metabolism_Homo sapiens_hsa004800.59742220
85p53 signaling pathway_Homo sapiens_hsa041150.57644395
86Proteasome_Homo sapiens_hsa030500.57073336
87Long-term potentiation_Homo sapiens_hsa047200.56753037
88Ovarian steroidogenesis_Homo sapiens_hsa049130.55679076
89Viral carcinogenesis_Homo sapiens_hsa052030.52574838
90MAPK signaling pathway_Homo sapiens_hsa040100.52382066
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.51907190
92ABC transporters_Homo sapiens_hsa020100.51631940
93AMPK signaling pathway_Homo sapiens_hsa041520.51525783
94Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.51013861
95Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49909084
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.48324514
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48078092
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.46747527
99cGMP-PKG signaling pathway_Homo sapiens_hsa040220.46707779
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46642453
101T cell receptor signaling pathway_Homo sapiens_hsa046600.46560130
102beta-Alanine metabolism_Homo sapiens_hsa004100.46488901
103Epstein-Barr virus infection_Homo sapiens_hsa051690.46073246
104VEGF signaling pathway_Homo sapiens_hsa043700.45693647
105Basal cell carcinoma_Homo sapiens_hsa052170.45224002
106Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.44761488
107Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43189326
108Arachidonic acid metabolism_Homo sapiens_hsa005900.40937690
109Endocytosis_Homo sapiens_hsa041440.40589033
110FoxO signaling pathway_Homo sapiens_hsa040680.38621696
111Drug metabolism - other enzymes_Homo sapiens_hsa009830.38425663
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.37763659
113Type II diabetes mellitus_Homo sapiens_hsa049300.37446852
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35988586
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.35984160
116Shigellosis_Homo sapiens_hsa051310.35588395
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.35346871
118HTLV-I infection_Homo sapiens_hsa051660.33521495
119Sphingolipid signaling pathway_Homo sapiens_hsa040710.33345824
120Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.32564486
121Alcoholism_Homo sapiens_hsa050340.32183106
122Chemical carcinogenesis_Homo sapiens_hsa052040.32058498
123Wnt signaling pathway_Homo sapiens_hsa043100.30894830
124Steroid hormone biosynthesis_Homo sapiens_hsa001400.29173424
125Inositol phosphate metabolism_Homo sapiens_hsa005620.28992210
126Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.28258415
127Nitrogen metabolism_Homo sapiens_hsa009100.28165852
128Calcium signaling pathway_Homo sapiens_hsa040200.27207553
129N-Glycan biosynthesis_Homo sapiens_hsa005100.27093319
130Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.23968111
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.23219474
132Metabolic pathways_Homo sapiens_hsa011000.22811383
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22266683
134Glutamatergic synapse_Homo sapiens_hsa047240.22129523
135Prostate cancer_Homo sapiens_hsa052150.21968431
136Influenza A_Homo sapiens_hsa051640.21517014
137Herpes simplex infection_Homo sapiens_hsa051680.19828779
138HIF-1 signaling pathway_Homo sapiens_hsa040660.19578202
139Chemokine signaling pathway_Homo sapiens_hsa040620.19357370
140Jak-STAT signaling pathway_Homo sapiens_hsa046300.19296141
141Longevity regulating pathway - mammal_Homo sapiens_hsa042110.18241995
142Lysine degradation_Homo sapiens_hsa003100.17504537
143Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.17470773
144Endometrial cancer_Homo sapiens_hsa052130.15596529
145Thyroid hormone synthesis_Homo sapiens_hsa049180.15472499
146Vascular smooth muscle contraction_Homo sapiens_hsa042700.14954909
147Long-term depression_Homo sapiens_hsa047300.14811939
148Ras signaling pathway_Homo sapiens_hsa040140.13662258
149Protein digestion and absorption_Homo sapiens_hsa049740.13502690

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »