DNAH12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm motility (GO:0030317)9.50410736
2acrosome assembly (GO:0001675)9.49311119
3multicellular organism reproduction (GO:0032504)9.44415716
4piRNA metabolic process (GO:0034587)9.21274057
5sperm-egg recognition (GO:0035036)9.05988749
6axoneme assembly (GO:0035082)9.02783199
7binding of sperm to zona pellucida (GO:0007339)8.28302514
8male meiosis (GO:0007140)8.15275971
9ventricular system development (GO:0021591)8.14198947
10cell-cell recognition (GO:0009988)8.10930427
11plasma membrane fusion (GO:0045026)7.96506029
12reproduction (GO:0000003)7.50149052
13acrosome reaction (GO:0007340)7.47411029
14regulation of cilium movement (GO:0003352)7.22110856
15spermatid development (GO:0007286)7.15965512
16synaptonemal complex organization (GO:0070193)6.96787124
17cell wall macromolecule catabolic process (GO:0016998)6.87925531
18cell wall macromolecule metabolic process (GO:0044036)6.87925531
19single fertilization (GO:0007338)6.72957600
20synaptonemal complex assembly (GO:0007130)6.34742630
21nucleoside diphosphate phosphorylation (GO:0006165)6.31988263
22intraciliary transport (GO:0042073)6.29597418
23GTP biosynthetic process (GO:0006183)6.18031120
24sperm capacitation (GO:0048240)6.03783944
25male meiosis I (GO:0007141)5.90799639
26fertilization (GO:0009566)5.78322129
27primary alcohol catabolic process (GO:0034310)5.76649782
28DNA methylation involved in gamete generation (GO:0043046)5.58242989
29UTP biosynthetic process (GO:0006228)5.50989112
30vitamin transmembrane transport (GO:0035461)5.45915847
31cilium organization (GO:0044782)5.24715664
32left/right axis specification (GO:0070986)5.19973500
33microtubule severing (GO:0051013)5.06280766
34negative regulation of inclusion body assembly (GO:0090084)5.04460816
35UTP metabolic process (GO:0046051)5.04346615
36diterpenoid biosynthetic process (GO:0016102)4.92989331
37ethanol metabolic process (GO:0006067)4.90601635
38cilium assembly (GO:0042384)4.89679169
39protein localization to cilium (GO:0061512)4.88252571
40spermatogenesis (GO:0007283)4.78753930
41meiotic cell cycle (GO:0051321)4.77387944
42male gamete generation (GO:0048232)4.77242071
43lateral ventricle development (GO:0021670)4.75604373
44meiosis I (GO:0007127)4.73411907
45* microtubule-based movement (GO:0007018)4.71197529
46chromosome organization involved in meiosis (GO:0070192)4.60540645
47meiotic nuclear division (GO:0007126)4.58219480
48centriole assembly (GO:0098534)4.56903229
49response to xenobiotic stimulus (GO:0009410)4.51729084
50cellular component assembly involved in morphogenesis (GO:0010927)4.47654049
51gamete generation (GO:0007276)4.41519946
52regulation of interleukin-5 production (GO:0032674)4.36339452
53microtubule bundle formation (GO:0001578)4.34136982
54cilium morphogenesis (GO:0060271)4.33019204
55retinal rod cell development (GO:0046548)4.24800496
56centriole replication (GO:0007099)4.22841517
57pyrimidine-containing compound transmembrane transport (GO:0072531)4.20872303
58regulation of microtubule-based movement (GO:0060632)4.19857697
59cellular process involved in reproduction in multicellular organism (GO:0022412)4.18481714
60germ cell development (GO:0007281)4.18264754
61guanosine-containing compound biosynthetic process (GO:1901070)4.07084719
62CTP metabolic process (GO:0046036)4.03394804
63CTP biosynthetic process (GO:0006241)4.03394804
64regulation of inclusion body assembly (GO:0090083)4.00192752
65one-carbon compound transport (GO:0019755)3.97827895
66cell recognition (GO:0008037)3.95901619
67retinal cone cell development (GO:0046549)3.95764119
68lung epithelium development (GO:0060428)3.90924265
69glomerular epithelial cell development (GO:0072310)3.86668651
70protein polyglutamylation (GO:0018095)3.82452882
71negative regulation of humoral immune response (GO:0002921)3.82324965
72tolerance induction (GO:0002507)3.80827464
73negative regulation of T cell differentiation in thymus (GO:0033085)3.75398525
74negative regulation of immunoglobulin mediated immune response (GO:0002890)3.72120983
75negative regulation of B cell mediated immunity (GO:0002713)3.72120983
76spermatid nucleus differentiation (GO:0007289)3.71992725
77regulation of interleukin-13 production (GO:0032656)3.69046149
78pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.68539753
79left/right pattern formation (GO:0060972)3.62958032
80cytoplasmic microtubule organization (GO:0031122)3.57448676
81ethanol oxidation (GO:0006069)3.53480398
82pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.51229508
83establishment of apical/basal cell polarity (GO:0035089)3.50432519
84microtubule polymerization or depolymerization (GO:0031109)3.49896121
85regulation of centriole replication (GO:0046599)3.48523580
86multicellular organismal reproductive process (GO:0048609)3.46599042
87pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.44960965
88nucleotide phosphorylation (GO:0046939)3.44058406
89regulation of germinal center formation (GO:0002634)3.38512027
90retinoic acid metabolic process (GO:0042573)3.38258192
91seminiferous tubule development (GO:0072520)3.37594097
92organic cation transport (GO:0015695)3.36455339
93calcium ion-dependent exocytosis (GO:0017156)3.35766481
94cell projection assembly (GO:0030031)3.34130603
95genitalia morphogenesis (GO:0035112)3.33209498
96terpenoid biosynthetic process (GO:0016114)3.27967885
97photoreceptor cell maintenance (GO:0045494)3.24961484
98gene silencing by RNA (GO:0031047)3.23495417
99negative regulation of organelle assembly (GO:1902116)3.19832882
100exogenous drug catabolic process (GO:0042738)3.16188342
101positive regulation of tolerance induction (GO:0002645)3.13373968
102pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.09468094
103establishment of monopolar cell polarity (GO:0061162)3.07845176
104establishment or maintenance of monopolar cell polarity (GO:0061339)3.07845176
105positive regulation of smoothened signaling pathway (GO:0045880)3.07826214
106establishment of planar polarity (GO:0001736)3.07034689
107establishment of tissue polarity (GO:0007164)3.07034689
108microtubule depolymerization (GO:0007019)3.05612699
109negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.04644459
110O-glycan processing (GO:0016266)3.03480466
111nucleoside diphosphate metabolic process (GO:0009132)3.02532915
112cilium or flagellum-dependent cell motility (GO:0001539)20.5618684
113determination of left/right symmetry (GO:0007368)2.91743451
114glutathione derivative metabolic process (GO:1901685)2.90352876
115glutathione derivative biosynthetic process (GO:1901687)2.90352876
116lateral sprouting from an epithelium (GO:0060601)2.88042446
117regulation of meiosis I (GO:0060631)2.85726414
118meiotic cell cycle process (GO:1903046)2.82769200
119regulation of protein polyubiquitination (GO:1902914)2.82515903
120synapsis (GO:0007129)2.81510555
121determination of bilateral symmetry (GO:0009855)2.81438261
122organelle assembly (GO:0070925)2.78955411
123monoubiquitinated protein deubiquitination (GO:0035520)2.77717694
124specification of symmetry (GO:0009799)2.74821403
125* microtubule-based process (GO:0007017)2.72652545
126protein refolding (GO:0042026)2.72171303
127otic vesicle formation (GO:0030916)2.71788454
128lactate metabolic process (GO:0006089)2.71160588
129primary alcohol metabolic process (GO:0034308)2.67299482
130retinol metabolic process (GO:0042572)2.63951927
131chaperone-mediated protein complex assembly (GO:0051131)2.63710051
132heart looping (GO:0001947)2.61952388
133multicellular organismal development (GO:0007275)2.60863828
134drug catabolic process (GO:0042737)2.56280968
135apical protein localization (GO:0045176)2.54973129
136phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.52516258
137carnitine metabolic process (GO:0009437)2.51273574
138brain morphogenesis (GO:0048854)2.50202449
139smoothened signaling pathway (GO:0007224)2.49946547
140regulation of microtubule depolymerization (GO:0031114)2.49108336
141hydrogen peroxide biosynthetic process (GO:0050665)2.45301731
142ADP metabolic process (GO:0046031)2.42417860
143multicellular organismal water homeostasis (GO:0050891)2.35498450
144embryonic heart tube morphogenesis (GO:0003143)2.35200629
145excretion (GO:0007588)2.34956035
146aldehyde catabolic process (GO:0046185)2.34146875
147nonmotile primary cilium assembly (GO:0035058)2.32851790
148phosphatidylcholine biosynthetic process (GO:0006656)2.32731971
149regulation of smoothened signaling pathway (GO:0008589)2.29447053
150regulation of collateral sprouting (GO:0048670)2.27169347
151regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.26428458
152protein O-linked glycosylation (GO:0006493)2.25806832
153intra-S DNA damage checkpoint (GO:0031573)2.25632700
154regulation of tolerance induction (GO:0002643)2.24382176
155asymmetric protein localization (GO:0008105)2.23327686
156CDP-diacylglycerol biosynthetic process (GO:0016024)2.22969713
157regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.20514498
158regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.19637659
159reactive oxygen species biosynthetic process (GO:1903409)2.16444119
160axonemal dynein complex assembly (GO:0070286)14.8385833
161cilium movement (GO:0003341)14.1984291
162epithelial cilium movement (GO:0003351)12.7763724
163epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)11.2826588
164fusion of sperm to egg plasma membrane (GO:0007342)10.4973240
165motile cilium assembly (GO:0044458)10.4794957

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.42209853
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.15053302
3EZH2_22144423_ChIP-Seq_EOC_Human4.39124667
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.87918712
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.84511347
6DROSHA_22980978_ChIP-Seq_HELA_Human3.23671657
7FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.09389350
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.68765945
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.65003846
10GATA1_26923725_Chip-Seq_HPCs_Mouse2.54422815
11TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.52101123
12PIAS1_25552417_ChIP-Seq_VCAP_Human2.36186102
13PCGF2_27294783_Chip-Seq_NPCs_Mouse2.36182970
14TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.16639669
15AHR_22903824_ChIP-Seq_MCF-7_Human2.15256231
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.12867296
17SUZ12_27294783_Chip-Seq_NPCs_Mouse2.09683968
18NFE2_27457419_Chip-Seq_LIVER_Mouse2.05282934
19PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.04003556
20FOXM1_26456572_ChIP-Seq_MCF-7_Human2.03894231
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.03487744
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.98945613
23ESR1_20079471_ChIP-ChIP_T-47D_Human1.96335290
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.92615590
25ARNT_22903824_ChIP-Seq_MCF-7_Human1.91471992
26NR3C1_21868756_ChIP-Seq_MCF10A_Human1.89838443
27ZNF217_24962896_ChIP-Seq_MCF-7_Human1.87787114
28RBPJ_22232070_ChIP-Seq_NCS_Mouse1.80543824
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.79300386
30KAP1_22055183_ChIP-Seq_ESCs_Mouse1.78941423
31AR_21572438_ChIP-Seq_LNCaP_Human1.78770275
32TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.74749558
33TP63_23658742_ChIP-Seq_EP156T_Human1.69337932
34RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.68315556
35TOP2B_26459242_ChIP-Seq_MCF-7_Human1.68114403
36TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.67187201
37KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.63878370
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.62633026
39RNF2_27304074_Chip-Seq_NSC_Mouse1.62375834
40FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.61911669
41EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.61717453
42EZH2_27294783_Chip-Seq_NPCs_Mouse1.59912968
43TAL1_26923725_Chip-Seq_HPCs_Mouse1.59012881
44ELK4_26923725_Chip-Seq_MESODERM_Mouse1.58515997
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.55944473
46TP53_18474530_ChIP-ChIP_U2OS_Human1.55750805
47CRX_20693478_ChIP-Seq_RETINA_Mouse1.54425290
48WDR5_24793694_ChIP-Seq_LNCAP_Human1.53736872
49NANOG_18555785_Chip-Seq_ESCs_Mouse1.53302380
50OCT4_18555785_Chip-Seq_ESCs_Mouse1.53259962
51AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.52987659
52TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.52774401
53ZNF274_21170338_ChIP-Seq_K562_Hela1.51782455
54ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.47768286
55P300_18555785_Chip-Seq_ESCs_Mouse1.45690773
56PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44770460
57STAT3_18555785_Chip-Seq_ESCs_Mouse1.43906765
58CBP_20019798_ChIP-Seq_JUKART_Human1.42353197
59IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42353197
60TRIM28_21343339_ChIP-Seq_HEK293_Human1.42329949
61P53_22387025_ChIP-Seq_ESCs_Mouse1.41067802
62CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.41034828
63ETV1_20927104_ChIP-Seq_GIST48_Human1.40088057
64STAT1_17558387_ChIP-Seq_HELA_Human1.39557610
65TP53_16413492_ChIP-PET_HCT116_Human1.39370960
66* SMRT_27268052_Chip-Seq_Bcells_Human1.38901273
67STAT1_20625510_ChIP-Seq_HELA_Human1.38849023
68TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.37350886
69EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.37157338
70* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.37138043
71KDM2B_26808549_Chip-Seq_REH_Human1.36159185
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.36088206
73OCT4_21477851_ChIP-Seq_ESCs_Mouse1.35769315
74SUZ12_18555785_Chip-Seq_ESCs_Mouse1.34965937
75POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34885417
76TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34885417
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.34075467
78PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.34033709
79GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.33314241
80KLF4_18555785_Chip-Seq_ESCs_Mouse1.32378930
81ESRRB_18555785_Chip-Seq_ESCs_Mouse1.32205845
82GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32068174
83ZFX_18555785_Chip-Seq_ESCs_Mouse1.31807170
84NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.30384704
85CMYC_18555785_Chip-Seq_ESCs_Mouse1.30069199
86BCAT_22108803_ChIP-Seq_LS180_Human1.29982876
87ER_23166858_ChIP-Seq_MCF-7_Human1.28469708
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.27551886
89TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26993297
90E2F1_18555785_Chip-Seq_ESCs_Mouse1.26424707
91PHF8_20622853_ChIP-Seq_HELA_Human1.25710556
92* FOXA1_25552417_ChIP-Seq_VCAP_Human1.25325121
93SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.24086561
94RUNX1_27457419_Chip-Seq_LIVER_Mouse1.24073707
95SOX9_24532713_ChIP-Seq_HFSC_Mouse1.23411290
96CTBP1_25329375_ChIP-Seq_LNCAP_Human1.23102452
97RUNX1_27514584_Chip-Seq_MCF-7_Human1.22403792
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.21498708
99SOX2_18555785_Chip-Seq_ESCs_Mouse1.21331780
100KLF5_25053715_ChIP-Seq_YYC3_Human1.20643426
101SOX2_27498859_Chip-Seq_STOMACH_Mouse1.20541283
102HNFA_21074721_ChIP-Seq_CACO-2_Human1.20380544
103FOXA1_25329375_ChIP-Seq_VCAP_Human1.19225086
104FOXA1_27270436_Chip-Seq_PROSTATE_Human1.19225086
105* SMAD4_21799915_ChIP-Seq_A2780_Human1.18945154
106GF1_26923725_Chip-Seq_HPCs_Mouse1.18892426
107ESR1_21235772_ChIP-Seq_MCF-7_Human1.18495983
108SMAD3_21741376_ChIP-Seq_HESCs_Human1.18159601
109SOX2_22085726_ChIP-Seq_NPCs_Mouse1.17233338
110PU1_27457419_Chip-Seq_LIVER_Mouse1.16377066
111CTCF_18555785_Chip-Seq_ESCs_Mouse1.15924105
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14874043
113ESR2_21235772_ChIP-Seq_MCF-7_Human1.14821746
114CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.14314946
115CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.14313138
116* TCF4_23295773_ChIP-Seq_U87_Human1.14025494
117CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13301739
118NFYA_21822215_ChIP-Seq_K562_Human1.13272887
119RBPJ_21746931_ChIP-Seq_IB4_Human1.12915488
120POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12634303
121VDR_22108803_ChIP-Seq_LS180_Human1.12200946
122SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.11617336
123CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11020064
124NMYC_18555785_Chip-Seq_ESCs_Mouse1.09795767
125GATA4_25053715_ChIP-Seq_YYC3_Human1.08295349
126LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.07908466
127SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07417583
128CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07036725
129STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.06984383
130ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.06691255
131CBX2_22325352_ChIP-Seq_293T-Rex_Human1.06190275
132EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05749834
133CDX2_22108803_ChIP-Seq_LS180_Human1.04972883
134RUNX2_22187159_ChIP-Seq_PCA_Human1.04670121
135SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.04022933
136SMAD1_18555785_Chip-Seq_ESCs_Mouse1.03992343
137TDRD3_21172665_ChIP-Seq_MCF-7_Human1.03595159
138SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.03300729
139GATA3_21867929_ChIP-Seq_CD8_Mouse1.02993534
140SMC4_20622854_ChIP-Seq_HELA_Human1.02957975
141REST_21632747_ChIP-Seq_MESCs_Mouse1.02752218
142SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.02451855
143PRDM14_20953172_ChIP-Seq_ESCs_Human1.02451518
144TP63_22573176_ChIP-Seq_HFKS_Human1.02152331
145FOXO3_23340844_ChIP-Seq_DLD1_Human1.01920483
146CEBPB_22108803_ChIP-Seq_LS180_Human1.01217894
147FOXA2_19822575_ChIP-Seq_HepG2_Human1.00516436
148NFYB_21822215_ChIP-Seq_K562_Human1.00136675
149CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.99663628
150TBL1_22424771_ChIP-Seq_293T_Human0.99510578
151* SMAD4_21741376_ChIP-Seq_EPCs_Human0.99088605
152SOX2_20726797_ChIP-Seq_SW620_Human0.98413224
153PPAR_26484153_Chip-Seq_NCI-H1993_Human0.98173304
154TAF15_26573619_Chip-Seq_HEK293_Human0.97754543
155GF1B_26923725_Chip-Seq_HPCs_Mouse0.97414604
156TCF4_22108803_ChIP-Seq_LS180_Human0.96921438
157BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.96348731
158RXR_22108803_ChIP-Seq_LS180_Human0.95956718
159PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.95824854
160GATA3_21867929_ChIP-Seq_TH1_Mouse0.95670251
161* STAT3_23295773_ChIP-Seq_U87_Human0.94428464
162AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.93898682
163P53_21459846_ChIP-Seq_SAOS-2_Human0.93593415
164AR_19668381_ChIP-Seq_PC3_Human0.93302631
165GATA6_21074721_ChIP-Seq_CACO-2_Human0.92851400
166FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.92697865
167P63_26484246_Chip-Seq_KERATINOCYTES_Human0.92651290
168FUS_26573619_Chip-Seq_HEK293_Human0.92475967
169* SMAD4_21741376_ChIP-Seq_HESCs_Human0.92418233
170CDX2_19796622_ChIP-Seq_MESCs_Mouse0.92402886

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok6.07177175
2MP0002653_abnormal_ependyma_morphology5.98375219
3MP0003698_abnormal_male_reproductive5.28642464
4MP0001929_abnormal_gametogenesis4.90435903
5MP0008877_abnormal_DNA_methylation4.51952960
6MP0005623_abnormal_meninges_morphology4.32528758
7MP0003136_yellow_coat_color4.15569311
8MP0004043_abnormal_pH_regulation3.87361237
9MP0002210_abnormal_sex_determination3.62486086
10MP0009780_abnormal_chondrocyte_physiolo3.37610937
11MP0001145_abnormal_male_reproductive2.94076287
12MP0002161_abnormal_fertility/fecundity2.83399286
13MP0008789_abnormal_olfactory_epithelium2.70971134
14MP0000653_abnormal_sex_gland2.65316752
15MP0000566_synostosis2.45743035
16MP0002160_abnormal_reproductive_system2.40357619
17MP0002282_abnormal_trachea_morphology2.38667517
18MP0010678_abnormal_skin_adnexa2.32582452
19MP0008057_abnormal_DNA_replication2.25204021
20MP0009046_muscle_twitch2.03403648
21MP0005410_abnormal_fertilization12.1050160
22MP0003950_abnormal_plasma_membrane1.84411620
23MP0005394_taste/olfaction_phenotype1.68675354
24MP0005499_abnormal_olfactory_system1.68675354
25MP0001346_abnormal_lacrimal_gland1.63061901
26MP0005083_abnormal_biliary_tract1.60776051
27MP0000678_abnormal_parathyroid_gland1.53010465
28MP0008058_abnormal_DNA_repair1.51450871
29MP0005395_other_phenotype1.49626230
30MP0008995_early_reproductive_senescence1.47339953
31MP0004133_heterotaxia1.44794694
32MP0001984_abnormal_olfaction1.44220469
33MP0005647_abnormal_sex_gland1.42620464
34MP0002876_abnormal_thyroid_physiology1.36062427
35MP0002909_abnormal_adrenal_gland1.34511250
36MP0002928_abnormal_bile_duct1.33937175
37MP0005389_reproductive_system_phenotype1.29252337
38MP0004381_abnormal_hair_follicle1.20644876
39MP0001765_abnormal_ion_homeostasis1.18352674
40MP0002734_abnormal_mechanical_nocicepti1.18052997
41MP0005248_abnormal_Harderian_gland1.16150413
42MP0001485_abnormal_pinna_reflex1.13624521
43MP0001851_eye_inflammation1.10792728
44MP0002102_abnormal_ear_morphology1.08840142
45MP0010030_abnormal_orbit_morphology1.08324297
46MP0005503_abnormal_tendon_morphology1.05958882
47MP0003646_muscle_fatigue1.05859069
48MP0005408_hypopigmentation1.00607544
49MP0005670_abnormal_white_adipose0.99951235
50MP0005646_abnormal_pituitary_gland0.99803815
51MP0003724_increased_susceptibility_to0.95386846
52MP0003195_calcinosis0.93410387
53MP0010094_abnormal_chromosome_stability0.91122463
54MP0005220_abnormal_exocrine_pancreas0.90481939
55MP0003011_delayed_dark_adaptation0.89314198
56MP0008004_abnormal_stomach_pH0.88747853
57MP0003786_premature_aging0.88458452
58MP0005388_respiratory_system_phenotype0.87971311
59MP0002133_abnormal_respiratory_system0.87971311
60MP0001545_abnormal_hematopoietic_system0.87913972
61MP0005397_hematopoietic_system_phenotyp0.87913972
62MP0005085_abnormal_gallbladder_physiolo0.86747727
63MP0005075_abnormal_melanosome_morpholog0.86464579
64MP0005310_abnormal_salivary_gland0.84522618
65MP0002405_respiratory_system_inflammati0.84084731
66MP0009643_abnormal_urine_homeostasis0.83997142
67MP0002735_abnormal_chemical_nociception0.83312506
68MP0001986_abnormal_taste_sensitivity0.82615239
69MP0001324_abnormal_eye_pigmentation0.82430989
70MP0000681_abnormal_thyroid_gland0.80743577
71MP0005164_abnormal_response_to0.80677622
72MP0002132_abnormal_respiratory_system0.79534976
73MP0002136_abnormal_kidney_physiology0.77968221
74MP0004134_abnormal_chest_morphology0.77586105
75MP0010234_abnormal_vibrissa_follicle0.76029138
76MP0005165_increased_susceptibility_to0.75909240
77MP0000026_abnormal_inner_ear0.75824915
78MP0010155_abnormal_intestine_physiology0.74826622
79MP0002638_abnormal_pupillary_reflex0.73583415
80MP0003890_abnormal_embryonic-extraembry0.73498494
81MP0002229_neurodegeneration0.73137529
82MP0008007_abnormal_cellular_replicative0.71905507
83MP0003937_abnormal_limbs/digits/tail_de0.71813385
84MP0003718_maternal_effect0.71624900
85MP0005423_abnormal_somatic_nervous0.69819692
86MP0000465_gastrointestinal_hemorrhage0.68281154
87MP0001879_abnormal_lymphatic_vessel0.66952810
88MP0005365_abnormal_bile_salt0.65925929
89MP0001958_emphysema0.65640070
90MP0004808_abnormal_hematopoietic_stem0.65353443
91MP0004883_abnormal_blood_vessel0.65133161
92MP0009765_abnormal_xenobiotic_induced0.63415009
93MP0001664_abnormal_digestion0.61272433
94MP0005253_abnormal_eye_physiology0.60393419
95MP0000428_abnormal_craniofacial_morphol0.60148215
96MP0000631_abnormal_neuroendocrine_gland0.59990368
97MP0001963_abnormal_hearing_physiology0.59276870
98MP0009703_decreased_birth_body0.58352242
99MP0001119_abnormal_female_reproductive0.58027046
100MP0002249_abnormal_larynx_morphology0.57530484
101MP0005551_abnormal_eye_electrophysiolog0.57222140
102MP0001944_abnormal_pancreas_morphology0.56837576
103MP0005391_vision/eye_phenotype0.56226798
104MP0009250_abnormal_appendicular_skeleto0.55874297
105MP0001502_abnormal_circadian_rhythm0.55256158
106MP0000427_abnormal_hair_cycle0.55213561
107MP0001293_anophthalmia0.54935886
108MP0000647_abnormal_sebaceous_gland0.54051845
109MP0001270_distended_abdomen0.52486598
110MP0001486_abnormal_startle_reflex0.51642974
111MP0000432_abnormal_head_morphology0.51151202
112MP0005636_abnormal_mineral_homeostasis0.50400636
113MP0003699_abnormal_female_reproductive0.49950705
114MP0002098_abnormal_vibrissa_morphology0.49541439
115MP0003045_fibrosis0.48675913
116MP0003656_abnormal_erythrocyte_physiolo0.48441658
117MP0004264_abnormal_extraembryonic_tissu0.48158094
118MP0009115_abnormal_fat_cell0.48100837
119MP0002139_abnormal_hepatobiliary_system0.48027191
120MP0001970_abnormal_pain_threshold0.47901429
121MP0000358_abnormal_cell_content/0.47856881
122MP0002135_abnormal_kidney_morphology0.47648094
123MP0004019_abnormal_vitamin_homeostasis0.46938362
124MP0001666_abnormal_nutrient_absorption0.46429007
125MP0002084_abnormal_developmental_patter0.45368429
126MP0003861_abnormal_nervous_system0.43877546
127MP0002116_abnormal_craniofacial_bone0.43871169
128MP0001299_abnormal_eye_distance/0.43448051
129MP0003943_abnormal_hepatobiliary_system0.42250386
130MP0002109_abnormal_limb_morphology0.40648440
131MP0005377_hearing/vestibular/ear_phenot0.39998547
132MP0003878_abnormal_ear_physiology0.39998547
133MP0003115_abnormal_respiratory_system0.38455250
134MP0001727_abnormal_embryo_implantation0.38139086
135MP0003634_abnormal_glial_cell0.38011160
136MP0002092_abnormal_eye_morphology0.37904003
137MP0002152_abnormal_brain_morphology0.36556586
138MP0003763_abnormal_thymus_physiology0.36510727
139MP0000383_abnormal_hair_follicle0.35428837
140MP0003942_abnormal_urinary_system0.35394993
141MP0002168_other_aberrant_phenotype0.34860602
142MP0001177_atelectasis0.33670811
143MP0002938_white_spotting0.33138229
144MP0002234_abnormal_pharynx_morphology0.31200506
145MP0000778_abnormal_nervous_system0.30171242
146MP0002233_abnormal_nose_morphology0.29365415
147MP0004782_abnormal_surfactant_physiolog0.29101693
148MP0000049_abnormal_middle_ear0.28864308
149MP0002277_abnormal_respiratory_mucosa0.28841254
150MP0008932_abnormal_embryonic_tissue0.27044513
151MP0003633_abnormal_nervous_system0.26936751
152MP0004742_abnormal_vestibular_system0.26830893
153MP0002557_abnormal_social/conspecific_i0.26444784
154MP0002254_reproductive_system_inflammat0.25972394
155MP0003279_aneurysm0.25610840
156MP0002095_abnormal_skin_pigmentation0.25583506
157MP0005195_abnormal_posterior_eye0.25551777
158MP0001175_abnormal_lung_morphology0.25306036

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)9.43311853
2Abnormal respiratory motile cilium morphology (HP:0005938)9.29500569
3Abnormal respiratory epithelium morphology (HP:0012253)9.29500569
4Chronic bronchitis (HP:0004469)7.06425717
5Nasal polyposis (HP:0100582)6.38632318
6Bronchiectasis (HP:0002110)5.76834864
7Abnormality of the nasal mucosa (HP:0000433)5.27867940
8Infertility (HP:0000789)4.81080310
9Bronchitis (HP:0012387)4.36045494
10Nephronophthisis (HP:0000090)4.07873370
11Recurrent sinusitis (HP:0011108)3.75474014
12Pancreatic fibrosis (HP:0100732)3.56158926
13Chronic sinusitis (HP:0011109)3.34725806
14Abnormality of the renal medulla (HP:0100957)3.19814685
15True hermaphroditism (HP:0010459)3.18356511
16Tubulointerstitial nephritis (HP:0001970)3.15900396
17Recurrent otitis media (HP:0000403)3.11115090
18Fibular hypoplasia (HP:0003038)3.05810547
19Chronic otitis media (HP:0000389)2.95054995
20Supernumerary spleens (HP:0009799)2.93391086
21Medial flaring of the eyebrow (HP:0010747)2.92977858
22Median cleft lip (HP:0000161)2.86684335
23Postaxial foot polydactyly (HP:0001830)2.82941597
24Abnormality of midbrain morphology (HP:0002418)2.80817016
25Molar tooth sign on MRI (HP:0002419)2.80817016
26Atelectasis (HP:0100750)2.63223047
27Congenital hepatic fibrosis (HP:0002612)2.63196886
28Hyperactive renin-angiotensin system (HP:0000841)2.58001919
29Male infertility (HP:0003251)2.56653228
30Recurrent bronchitis (HP:0002837)2.55792012
31Aplasia/Hypoplasia of the tongue (HP:0010295)2.48893543
32Cystic liver disease (HP:0006706)2.42011587
33Abnormality of the lower motor neuron (HP:0002366)2.33099171
34Pancreatic cysts (HP:0001737)2.25774756
35Tubulointerstitial abnormality (HP:0001969)2.25163778
36Occipital encephalocele (HP:0002085)2.22699158
37Facial cleft (HP:0002006)2.20988733
38Tubular atrophy (HP:0000092)2.20134780
39Congenital primary aphakia (HP:0007707)2.19111703
40Gait imbalance (HP:0002141)2.19094997
41Amyotrophic lateral sclerosis (HP:0007354)2.15699311
42Absent rod-and cone-mediated responses on ERG (HP:0007688)2.15326009
4311 pairs of ribs (HP:0000878)2.12246590
44Abnormal biliary tract physiology (HP:0012439)2.09271534
45Bile duct proliferation (HP:0001408)2.09271534
46Microglossia (HP:0000171)2.06004194
47Abnormality of dentin (HP:0010299)2.04757073
48Stage 5 chronic kidney disease (HP:0003774)2.03567995
49Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.8805083
50Abnormal respiratory motile cilium physiology (HP:0012261)11.5580795
51Abnormal ciliary motility (HP:0012262)10.9208101
52Dynein arm defect of respiratory motile cilia (HP:0012255)10.4441608
53Absent/shortened dynein arms (HP:0200106)10.4441608
54Nephrogenic diabetes insipidus (HP:0009806)1.95653846
55Aplasia/Hypoplasia of the fibula (HP:0006492)1.93539749
56Abnormality of permanent molar morphology (HP:0011071)1.86818352
57Abnormality of the dental root (HP:0006486)1.86818352
58Taurodontia (HP:0000679)1.86818352
59Postaxial hand polydactyly (HP:0001162)1.86366116
60Oculomotor apraxia (HP:0000657)1.82500322
61Genital tract atresia (HP:0001827)1.81139422
62Decreased circulating renin level (HP:0003351)1.78028078
63J-shaped sella turcica (HP:0002680)1.76705947
64Abnormality of molar (HP:0011077)1.76470302
65Abnormality of molar morphology (HP:0011070)1.76470302
66Abnormality of the dental pulp (HP:0006479)1.69811029
67Furrowed tongue (HP:0000221)1.68670185
68Short ribs (HP:0000773)1.68635572
69Preaxial hand polydactyly (HP:0001177)1.68024009
70Chronic hepatic failure (HP:0100626)1.65273183
71Abnormal spermatogenesis (HP:0008669)1.64946323
72Abnormality of the renal cortex (HP:0011035)1.64167239
73Asplenia (HP:0001746)1.63738463
74Tubulointerstitial fibrosis (HP:0005576)1.62363270
75Poor coordination (HP:0002370)1.60589968
76Aplasia/Hypoplasia of the spleen (HP:0010451)1.60343202
77Impaired proprioception (HP:0010831)1.58666571
78Male pseudohermaphroditism (HP:0000037)1.58289903
79Gonadotropin excess (HP:0000837)1.56709260
80Vaginal atresia (HP:0000148)1.52463274
81Hyperkalemia (HP:0002153)1.52328438
82Anencephaly (HP:0002323)1.52161824
83Cone-rod dystrophy (HP:0000548)1.51801248
84Absent frontal sinuses (HP:0002688)1.51039495
85Hypoplasia of the capital femoral epiphysis (HP:0003090)1.49987849
86Renal salt wasting (HP:0000127)1.47989343
87Short thorax (HP:0010306)1.47904150
88Abnormal drinking behavior (HP:0030082)1.46518902
89Polydipsia (HP:0001959)1.46518902
90Azoospermia (HP:0000027)1.44918336
91Renal dysplasia (HP:0000110)1.43104339
92Nephropathy (HP:0000112)1.40761337
93Abnormal rod and cone electroretinograms (HP:0008323)1.39632577
94Upper motor neuron abnormality (HP:0002127)1.37267199
95Aplasia/Hypoplasia of the lens (HP:0008063)1.34642794
96Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.34334906
97Bell-shaped thorax (HP:0001591)1.32907469
98Polycystic kidney dysplasia (HP:0000113)1.32073355
99Short nail (HP:0001799)1.30919964
100Hyperaldosteronism (HP:0000859)1.30593930
101Missing ribs (HP:0000921)1.29475212
102Abnormality of renin-angiotensin system (HP:0000847)1.25090357
103Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.24423989
104Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.24239362
105Absent epiphyses (HP:0010577)1.24239362
106Sclerocornea (HP:0000647)1.23476775
107Decreased central vision (HP:0007663)1.20627563
108Narrow chest (HP:0000774)1.20453635
109Metaphyseal dysplasia (HP:0100255)1.18022752
110Abnormality of renal excretion (HP:0011036)1.16839293
111Abnormality of chloride homeostasis (HP:0011422)1.13846366
112Broad distal phalanx of finger (HP:0009836)1.13716762
113Aplasia/Hypoplasia of the tibia (HP:0005772)1.13705865
114Hypodontia (HP:0000668)1.13113465
115Short tibia (HP:0005736)1.12155671
116Abnormality of abdominal situs (HP:0011620)1.08733333
117Retinitis pigmentosa (HP:0000510)1.08590464
118Hypokalemic alkalosis (HP:0001949)1.08288652
119Abnormality of the frontal sinuses (HP:0002687)1.08092930
120Glucose intolerance (HP:0000833)1.06052389
121Bony spicule pigmentary retinopathy (HP:0007737)1.04881629
122Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.03834999
123Bifid scrotum (HP:0000048)1.03045902
124Abnormality of macular pigmentation (HP:0008002)0.99774896
125Portal hypertension (HP:0001409)0.99256158
126Narrow forehead (HP:0000341)0.97717876
127Lip pit (HP:0100267)0.96331928
128Prominent nasal bridge (HP:0000426)0.95400032

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.50313932
2PDK48.50313932
3PDK25.47481524
4PNCK4.69965820
5MAPK154.22028813
6EPHA23.90412842
7FRK2.71628429
8PTK2B2.43213938
9STK392.34843779
10TESK12.34460336
11MAPKAPK32.25028064
12WNK42.22929887
13MAP3K22.15939324
14BCR2.05612900
15STK241.93389849
16PRKD31.80325750
17WEE11.74522476
18ICK1.51503945
19MST41.43311449
20NEK21.27515642
21STK31.24537711
22TRPM71.22705291
23MAP3K31.19008658
24MAP3K71.14919577
25WNK11.11743431
26BRSK21.08571005
27TTK1.07923662
28IRAK11.01005260
29MAP3K41.00421660
30TLK10.95732513
31DAPK20.93835362
32ACVR1B0.91819656
33DYRK30.90632529
34EPHB10.89347792
35LMTK20.89331536
36EPHA30.89031382
37ERBB20.88022467
38STK160.85323316
39ERBB30.84316135
40LRRK20.83504508
41STK100.81811203
42STK380.80846129
43INSRR0.76421305
44PRKCI0.73379710
45NLK0.71285456
46CDC70.71028088
47NTRK20.69569148
48LATS10.68684655
49PINK10.65913204
50PLK40.63451615
51GRK10.63336909
52SMG10.60872427
53PDK10.58877313
54NEK90.57157653
55MAPKAPK50.56679261
56STK38L0.56454591
57CAMK1G0.55958559
58FER0.55174777
59CAMKK20.53902232
60TYRO30.52031136
61RIPK40.51322304
62OXSR10.51259638
63MET0.50596556
64CAMKK10.49614910
65TBK10.49063680
66ZAK0.48428253
67ADRBK10.47928351
68NEK60.47519467
69CDK30.46125589
70CHEK20.45442643
71AURKA0.44396268
72SGK10.43988953
73MAPK130.43538561
74EEF2K0.43445808
75ATR0.41402989
76TEC0.39285525
77MAP2K20.38150715
78PAK20.37825813
79ITK0.37773692
80NTRK30.37460400
81PASK0.37456564
82ATM0.36004019
83CHEK10.35878305
84MAP2K70.34791674
85CDC42BPA0.34122960
86CAMK2G0.34083312
87CSK0.33103060
88PRKCD0.32988500
89PLK10.32072151
90WNK30.31989215
91CCNB10.31268796
92HIPK20.30666416
93TYK20.30409431
94SGK4940.29597138
95SGK2230.29597138
96FGFR30.29413055
97PRKCG0.29378602
98GSK3A0.28885191
99ABL10.28314280
100PDPK10.25726739
101CAMK2A0.25652963
102PRKCE0.24662925
103PRKCA0.24556987
104AKT20.23084088
105CDK120.23065681
106RET0.22922713
107TGFBR10.22237805
108BRD40.22076257
109BRSK10.21753672
110ADRBK20.21049621
111RPS6KB20.20808444
112PAK10.19974310
113MAP2K40.19208875
114PRKCZ0.18969771
115MELK0.18762617
116CHUK0.18456877
117FYN0.18228837
118ROCK20.17539973
119PRKDC0.17252981
120PRKG10.17134117
121BMPR1B0.16234252
122PRKAA10.15521322
123MUSK0.14297573
124DYRK1B0.14154648
125PKN10.13845324
126RPS6KB10.13441794
127SGK20.12060295
128PRKACG0.10793891
129MST1R0.10537151
130STK110.10372350
131MAPK100.10154522
132CSNK2A10.09820164
133MARK20.09614244
134IRAK20.08447502
135ROCK10.08359148
136PHKG20.08339384
137PHKG10.08339384
138PRKCH0.08221977
139ZAP700.07740436
140DYRK1A0.07219372
141NME10.06944449
142CSNK2A20.06594578
143PRKACA0.06490860
144PRKCQ0.06369968
145MAPK80.06309734
146CDK40.06250054
147GSK3B0.05236982
148CDK10.05141232
149TXK0.04665329
150EGFR0.04363100
151SRC0.04353062
152PRKAA20.04083354
153PRKACB0.03975383
154RPS6KA20.03973742
155GRK50.03955142
156MTOR0.03709653

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.78808205
2Phenylalanine metabolism_Homo sapiens_hsa003604.13262118
3Pyruvate metabolism_Homo sapiens_hsa006203.83894086
4Huntingtons disease_Homo sapiens_hsa050163.43082373
5Fanconi anemia pathway_Homo sapiens_hsa034603.19840277
6Propanoate metabolism_Homo sapiens_hsa006403.15842770
7Tyrosine metabolism_Homo sapiens_hsa003503.13242868
8Basal transcription factors_Homo sapiens_hsa030222.97576534
9beta-Alanine metabolism_Homo sapiens_hsa004102.77529592
10Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.76518104
11Dorso-ventral axis formation_Homo sapiens_hsa043202.66820710
12Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.50095027
13Pentose phosphate pathway_Homo sapiens_hsa000302.47192511
14Caffeine metabolism_Homo sapiens_hsa002322.43124172
15Glucagon signaling pathway_Homo sapiens_hsa049222.33244967
16Linoleic acid metabolism_Homo sapiens_hsa005912.17033757
17Fatty acid biosynthesis_Homo sapiens_hsa000612.06160589
18Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.86408629
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.82525800
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.75644628
21Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.74119175
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.69536808
23Oocyte meiosis_Homo sapiens_hsa041141.58700127
24Selenocompound metabolism_Homo sapiens_hsa004501.52525241
25PPAR signaling pathway_Homo sapiens_hsa033201.48424084
26Glycosaminoglycan degradation_Homo sapiens_hsa005311.47013327
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.41945931
28Amphetamine addiction_Homo sapiens_hsa050311.39287796
29Tight junction_Homo sapiens_hsa045301.37882705
30Glycerolipid metabolism_Homo sapiens_hsa005611.31954355
31Purine metabolism_Homo sapiens_hsa002301.31274506
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.30091005
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.28714856
34Histidine metabolism_Homo sapiens_hsa003401.28587443
35Arachidonic acid metabolism_Homo sapiens_hsa005901.26537401
36Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.23483259
37Homologous recombination_Homo sapiens_hsa034401.21520752
38Ether lipid metabolism_Homo sapiens_hsa005651.17126565
39Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.15528387
40Renin secretion_Homo sapiens_hsa049241.12697866
41Fatty acid degradation_Homo sapiens_hsa000711.12366629
42ABC transporters_Homo sapiens_hsa020101.10727709
43Starch and sucrose metabolism_Homo sapiens_hsa005001.09522602
44Cysteine and methionine metabolism_Homo sapiens_hsa002701.05208570
45Antigen processing and presentation_Homo sapiens_hsa046121.02264657
46Mineral absorption_Homo sapiens_hsa049781.01923502
47Peroxisome_Homo sapiens_hsa041461.00057410
48Retinol metabolism_Homo sapiens_hsa008300.99756399
49Cardiac muscle contraction_Homo sapiens_hsa042600.99628835
50Taste transduction_Homo sapiens_hsa047420.95451524
51Glutathione metabolism_Homo sapiens_hsa004800.95072515
52Glycerophospholipid metabolism_Homo sapiens_hsa005640.93190191
53Primary bile acid biosynthesis_Homo sapiens_hsa001200.91167183
54mRNA surveillance pathway_Homo sapiens_hsa030150.89835132
55Hedgehog signaling pathway_Homo sapiens_hsa043400.88397603
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.86137088
57Calcium signaling pathway_Homo sapiens_hsa040200.85455966
58Chemical carcinogenesis_Homo sapiens_hsa052040.81764610
59Olfactory transduction_Homo sapiens_hsa047400.81298324
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.81089160
61Renin-angiotensin system_Homo sapiens_hsa046140.80596112
62Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.76165624
63Nicotine addiction_Homo sapiens_hsa050330.72146708
64Choline metabolism in cancer_Homo sapiens_hsa052310.70307268
65Adherens junction_Homo sapiens_hsa045200.68481615
66Drug metabolism - other enzymes_Homo sapiens_hsa009830.67742346
67Ovarian steroidogenesis_Homo sapiens_hsa049130.66485344
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66456201
69Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.65237908
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64561736
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64302429
72Carbon metabolism_Homo sapiens_hsa012000.64176232
73RNA degradation_Homo sapiens_hsa030180.63596746
74Circadian rhythm_Homo sapiens_hsa047100.59980312
75Serotonergic synapse_Homo sapiens_hsa047260.59660466
76Inositol phosphate metabolism_Homo sapiens_hsa005620.57851835
77Hematopoietic cell lineage_Homo sapiens_hsa046400.57278307
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.56633891
79Wnt signaling pathway_Homo sapiens_hsa043100.56474346
80Leukocyte transendothelial migration_Homo sapiens_hsa046700.55252296
81Pyrimidine metabolism_Homo sapiens_hsa002400.54889261
82Basal cell carcinoma_Homo sapiens_hsa052170.53691310
83Gastric acid secretion_Homo sapiens_hsa049710.50890765
84Thyroid hormone synthesis_Homo sapiens_hsa049180.50840113
85cGMP-PKG signaling pathway_Homo sapiens_hsa040220.49999395
86Estrogen signaling pathway_Homo sapiens_hsa049150.49853188
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49179379
88Nucleotide excision repair_Homo sapiens_hsa034200.48794061
89Nitrogen metabolism_Homo sapiens_hsa009100.48759673
90Notch signaling pathway_Homo sapiens_hsa043300.48208915
91Hepatitis C_Homo sapiens_hsa051600.47210801
92RNA transport_Homo sapiens_hsa030130.47013141
93Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46617693
94Metabolic pathways_Homo sapiens_hsa011000.44952336
95Systemic lupus erythematosus_Homo sapiens_hsa053220.44616644
96Cell cycle_Homo sapiens_hsa041100.44547043
97Sphingolipid metabolism_Homo sapiens_hsa006000.43391095
98Protein digestion and absorption_Homo sapiens_hsa049740.43274683
99Insulin secretion_Homo sapiens_hsa049110.41614461
100Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.40473404
101Tryptophan metabolism_Homo sapiens_hsa003800.40315638
102Collecting duct acid secretion_Homo sapiens_hsa049660.39434635
103AMPK signaling pathway_Homo sapiens_hsa041520.38828170
104Pancreatic secretion_Homo sapiens_hsa049720.37990125
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36451145
106Glutamatergic synapse_Homo sapiens_hsa047240.35073999
107Jak-STAT signaling pathway_Homo sapiens_hsa046300.34856389
108Phototransduction_Homo sapiens_hsa047440.34618462
109Salmonella infection_Homo sapiens_hsa051320.32668199
110Bile secretion_Homo sapiens_hsa049760.31755423
111Complement and coagulation cascades_Homo sapiens_hsa046100.31631585
112ECM-receptor interaction_Homo sapiens_hsa045120.31143037
113Vitamin digestion and absorption_Homo sapiens_hsa049770.30386220
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.29045737
115Amoebiasis_Homo sapiens_hsa051460.28945799
116Long-term potentiation_Homo sapiens_hsa047200.28900565
117Cocaine addiction_Homo sapiens_hsa050300.28854586
118Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28420102
119cAMP signaling pathway_Homo sapiens_hsa040240.28343593
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.27578266
121Regulation of autophagy_Homo sapiens_hsa041400.27576882
122Butanoate metabolism_Homo sapiens_hsa006500.27317742
123Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27180118
124N-Glycan biosynthesis_Homo sapiens_hsa005100.26937996
125Salivary secretion_Homo sapiens_hsa049700.26543055
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.26237455
127Autoimmune thyroid disease_Homo sapiens_hsa053200.26049411
128Arginine and proline metabolism_Homo sapiens_hsa003300.24820880
129Maturity onset diabetes of the young_Homo sapiens_hsa049500.24433690
130Sulfur metabolism_Homo sapiens_hsa009200.24209239
131Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.24004049
132Biosynthesis of amino acids_Homo sapiens_hsa012300.23878764
133Circadian entrainment_Homo sapiens_hsa047130.23632287
134Lysine degradation_Homo sapiens_hsa003100.22776524
135Sphingolipid signaling pathway_Homo sapiens_hsa040710.21370466
136Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.20856601
137Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.20783947
138Hippo signaling pathway_Homo sapiens_hsa043900.20392345
139HTLV-I infection_Homo sapiens_hsa051660.20116713
140Adipocytokine signaling pathway_Homo sapiens_hsa049200.19962800
141Type I diabetes mellitus_Homo sapiens_hsa049400.19385120
142Viral carcinogenesis_Homo sapiens_hsa052030.18704717
143Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18453185
144T cell receptor signaling pathway_Homo sapiens_hsa046600.17781555
145Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.16398154
146Insulin resistance_Homo sapiens_hsa049310.14451646
147Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.13750750
148Graft-versus-host disease_Homo sapiens_hsa053320.13403221
149Asthma_Homo sapiens_hsa053100.10992790
150Dilated cardiomyopathy_Homo sapiens_hsa054140.09194668
151Intestinal immune network for IgA production_Homo sapiens_hsa046720.09049922
152Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.07895948

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »