DNAJB14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1deoxyribonucleoside diphosphate metabolic process (GO:0009186)4.81704140
2establishment of protein localization to Golgi (GO:0072600)4.71115091
3protein targeting to Golgi (GO:0000042)4.60014773
4neuron cell-cell adhesion (GO:0007158)4.37277488
5retrograde transport, vesicle recycling within Golgi (GO:0000301)4.24247985
6protein K11-linked deubiquitination (GO:0035871)4.09187892
7regulation of pigment cell differentiation (GO:0050932)4.02863213
8neuronal action potential propagation (GO:0019227)3.98851384
9regulation of short-term neuronal synaptic plasticity (GO:0048172)3.97158543
10startle response (GO:0001964)3.87256475
11ionotropic glutamate receptor signaling pathway (GO:0035235)3.83819124
12neural tube formation (GO:0001841)3.83442991
13protein localization to synapse (GO:0035418)3.81864925
14positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.73463156
15cellular response to ethanol (GO:0071361)3.70272298
16negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.68054165
17nerve growth factor signaling pathway (GO:0038180)3.67003392
18presynaptic membrane assembly (GO:0097105)3.64159689
19negative regulation of neurotransmitter secretion (GO:0046929)3.61313070
20synaptic transmission, glutamatergic (GO:0035249)3.53074326
21phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.48799654
22regulation of B cell receptor signaling pathway (GO:0050855)3.46635730
23presynaptic membrane organization (GO:0097090)3.46397575
24monoubiquitinated protein deubiquitination (GO:0035520)3.45845772
25axon ensheathment in central nervous system (GO:0032291)3.45760245
26central nervous system myelination (GO:0022010)3.45760245
27positive regulation of developmental pigmentation (GO:0048087)3.44370383
28glutamate receptor signaling pathway (GO:0007215)3.43464695
29transmission of nerve impulse (GO:0019226)3.41114242
30positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.40821767
31vocalization behavior (GO:0071625)3.40370721
32deoxyribonucleotide biosynthetic process (GO:0009263)3.40229708
33neuron-neuron synaptic transmission (GO:0007270)3.37225972
34protein prenylation (GO:0018342)3.35999766
35prenylation (GO:0097354)3.35999766
36long-chain fatty acid biosynthetic process (GO:0042759)3.33971959
37calcium ion-dependent exocytosis (GO:0017156)3.33823079
38L-amino acid import (GO:0043092)3.33031980
39proline transport (GO:0015824)3.29178299
40regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.28911260
41negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)3.26363247
42gamma-aminobutyric acid signaling pathway (GO:0007214)3.22329095
43regulation of establishment of cell polarity (GO:2000114)3.21429530
44protein localization to Golgi apparatus (GO:0034067)3.20379552
45regulation of protein kinase A signaling (GO:0010738)3.19854372
46synaptic vesicle exocytosis (GO:0016079)3.17754546
47long-term memory (GO:0007616)3.14451562
48phospholipid translocation (GO:0045332)3.11688502
49lipid translocation (GO:0034204)3.11688502
50negative regulation of synaptic transmission, GABAergic (GO:0032229)3.08569368
51righting reflex (GO:0060013)3.05789843
52RNA destabilization (GO:0050779)3.04596119
53termination of RNA polymerase III transcription (GO:0006386)3.03551442
54transcription elongation from RNA polymerase III promoter (GO:0006385)3.03551442
55regulation of protein glycosylation (GO:0060049)3.01878803
56neurotransmitter uptake (GO:0001504)3.01843775
57positive regulation of muscle hypertrophy (GO:0014742)3.01647047
58positive regulation of cardiac muscle hypertrophy (GO:0010613)3.01647047
59glutamate secretion (GO:0014047)3.00013439
60regulation of Rac protein signal transduction (GO:0035020)2.98079842
61DNA methylation involved in gamete generation (GO:0043046)2.97330178
62positive regulation of granulocyte differentiation (GO:0030854)2.96463573
63synaptic vesicle maturation (GO:0016188)2.96194483
64amino acid import (GO:0043090)2.95117697
65piRNA metabolic process (GO:0034587)2.93789038
66deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.93298781
67activated T cell proliferation (GO:0050798)2.92240640
68regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.91496729
69locomotory exploration behavior (GO:0035641)2.90877241
70intra-Golgi vesicle-mediated transport (GO:0006891)2.90326493
71regulation of synaptic vesicle transport (GO:1902803)2.89773341
72Golgi to endosome transport (GO:0006895)2.89436610
73dopamine transport (GO:0015872)2.89156652
74negative regulation of neurotransmitter transport (GO:0051589)2.87810267
75regulation of glutamate receptor signaling pathway (GO:1900449)2.87217208
76positive regulation of prostaglandin secretion (GO:0032308)2.87209906
77regulation of synaptic vesicle exocytosis (GO:2000300)2.86002317
78adult walking behavior (GO:0007628)2.82234286
79Rap protein signal transduction (GO:0032486)2.80438498
80regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)2.79437616
81regulation of excitatory postsynaptic membrane potential (GO:0060079)2.79431560
82regulation of neuronal synaptic plasticity (GO:0048168)2.78748673
83regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.78725791
84mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.78597969
85regulation of long-term neuronal synaptic plasticity (GO:0048169)2.78190205
86regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.76956848
87postsynaptic membrane organization (GO:0001941)2.76795812
88regulation of vesicle fusion (GO:0031338)2.75467073
89negative regulation of NF-kappaB import into nucleus (GO:0042347)2.75403054
90establishment of protein localization to mitochondrial membrane (GO:0090151)2.73696637
91G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.72198347
92neuron recognition (GO:0008038)2.71259297
93regulation of postsynaptic membrane potential (GO:0060078)2.70736233
94positive regulation of membrane potential (GO:0045838)2.68992989
95fucose catabolic process (GO:0019317)2.68199883
96L-fucose metabolic process (GO:0042354)2.68199883
97L-fucose catabolic process (GO:0042355)2.68199883
98response to pheromone (GO:0019236)2.67391223
99regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.65141607
100neurotransmitter transport (GO:0006836)2.64862345
101neurotransmitter catabolic process (GO:0042135)2.63244637
102protein localization to cilium (GO:0061512)2.62147893
103regulation of establishment or maintenance of cell polarity (GO:0032878)2.60972901
104cilium or flagellum-dependent cell motility (GO:0001539)2.60800946
105synaptonemal complex assembly (GO:0007130)2.59188805
106regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.59088531
107acrosome reaction (GO:0007340)2.57618484
108regulation of nuclear cell cycle DNA replication (GO:0033262)2.57606492
109protein neddylation (GO:0045116)2.56513170
110regulation of catecholamine metabolic process (GO:0042069)2.56424190
111regulation of dopamine metabolic process (GO:0042053)2.56424190
112cellular response to interleukin-15 (GO:0071350)2.56183665
113regulation of glucokinase activity (GO:0033131)2.56136925
114regulation of hexokinase activity (GO:1903299)2.56136925
115positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.55758690
116signal peptide processing (GO:0006465)2.54878575
117axonemal dynein complex assembly (GO:0070286)2.54201621
118chaperone-mediated protein transport (GO:0072321)2.53997892
119interleukin-6-mediated signaling pathway (GO:0070102)2.53585706
120positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)2.53536787
121neuromuscular process controlling posture (GO:0050884)2.52848474
122epithelial cilium movement (GO:0003351)2.52230354
123GTP biosynthetic process (GO:0006183)2.52224958
124glycerophospholipid catabolic process (GO:0046475)2.52080010
125regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.52039823
126regulation of prostaglandin secretion (GO:0032306)2.51981108
127cilium movement (GO:0003341)2.51523319
128synaptonemal complex organization (GO:0070193)2.51489067
129protein-cofactor linkage (GO:0018065)2.51130717
130negative regulation of exocytosis (GO:0045920)2.50213799
131regulation of respiratory gaseous exchange (GO:0043576)2.50196474
132neurotransmitter secretion (GO:0007269)2.50011184
133positive regulation of glycolytic process (GO:0045821)2.49754587
134cerebellar Purkinje cell differentiation (GO:0021702)2.48793700
135magnesium ion transport (GO:0015693)2.48719297
136negative T cell selection (GO:0043383)2.48502028
137keratinocyte development (GO:0003334)2.47648710
138positive regulation of synaptic transmission, GABAergic (GO:0032230)2.47166532
139regulation of neurotransmitter secretion (GO:0046928)2.46908931
140regulation of fibroblast apoptotic process (GO:2000269)2.46506675
141neuronal ion channel clustering (GO:0045161)2.46318177
142dentate gyrus development (GO:0021542)2.45760751
143exploration behavior (GO:0035640)2.45069093
144early endosome to late endosome transport (GO:0045022)2.44055914
145negative regulation of cytosolic calcium ion concentration (GO:0051481)2.43959773
146cyclic nucleotide catabolic process (GO:0009214)2.43861663
147gamma-aminobutyric acid transport (GO:0015812)2.43639741
148cAMP catabolic process (GO:0006198)2.43472324
149peptidyl-threonine dephosphorylation (GO:0035970)2.43363900
150membrane depolarization (GO:0051899)2.43247189
151membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.42973217
152positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.42846006
153positive regulation of cardiac muscle cell differentiation (GO:2000727)2.42348564
154axonal fasciculation (GO:0007413)2.42294436
155regulation of T cell receptor signaling pathway (GO:0050856)2.42262781
156protein targeting to lysosome (GO:0006622)2.42079229
157establishment of protein localization to vacuole (GO:0072666)2.42079229
158protein targeting to vacuole (GO:0006623)2.42079229
159serotonin metabolic process (GO:0042428)2.41738829
160regulation of respiratory system process (GO:0044065)2.41366774
161positive regulation of synapse assembly (GO:0051965)2.41057857
162response to interleukin-15 (GO:0070672)2.40986851
163male meiosis (GO:0007140)2.40342773
164negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.39926003
165inositol phosphate-mediated signaling (GO:0048016)2.39016515
166inositol phosphate catabolic process (GO:0071545)2.37829310
167positive regulation of phosphatase activity (GO:0010922)2.36908122
168positive regulation of protein autophosphorylation (GO:0031954)2.35676671
169adaptation of signaling pathway (GO:0023058)2.34328333
170hepatocyte apoptotic process (GO:0097284)2.33763778
171regulation of germinal center formation (GO:0002634)2.33535776
172RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.32345380
173regulation of sarcomere organization (GO:0060297)2.31817993
174interferon-gamma production (GO:0032609)2.30733347
175negative regulation of T cell mediated immunity (GO:0002710)2.30110814
176regulation of protein polyubiquitination (GO:1902914)2.28064993
177negative thymic T cell selection (GO:0045060)2.27465028
178reflex (GO:0060004)2.26176886
179positive regulation of mRNA catabolic process (GO:0061014)2.25655773
180establishment of nucleus localization (GO:0040023)2.24608457
181histone mRNA catabolic process (GO:0071044)2.24469095
182protein K63-linked deubiquitination (GO:0070536)2.23970692
183prostate gland growth (GO:0060736)2.23963849
184retinal cone cell development (GO:0046549)2.21061116
185polyol catabolic process (GO:0046174)2.19045798
186negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.16924972
187primary amino compound metabolic process (GO:1901160)2.16841768
188regulation of memory T cell differentiation (GO:0043380)2.16283921
189necroptotic process (GO:0070266)2.15833851
190regulation of developmental pigmentation (GO:0048070)2.15205056
191intracellular lipid transport (GO:0032365)2.14839124
192negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.12654793
193negative regulation of cell killing (GO:0031342)2.12654793

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.08719619
2GBX2_23144817_ChIP-Seq_PC3_Human3.55394840
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.27169793
4CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.98764635
5SMAD_19615063_ChIP-ChIP_OVARY_Human2.71231844
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.70744468
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.69263565
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.50266240
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.49482042
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.41631969
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.35630178
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.28327065
13SALL1_21062744_ChIP-ChIP_HESCs_Human2.18519057
14TAF15_26573619_Chip-Seq_HEK293_Human2.17430588
15PCGF2_27294783_Chip-Seq_ESCs_Mouse2.15531384
16REST_21632747_ChIP-Seq_MESCs_Mouse2.10336283
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.06801973
18FUS_26573619_Chip-Seq_HEK293_Human2.05391031
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.99034323
20SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.98479125
21JARID2_20064375_ChIP-Seq_MESCs_Mouse1.97747288
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.97442897
23BMI1_23680149_ChIP-Seq_NPCS_Mouse1.92519549
24STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.88148160
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.84474577
26SUZ12_27294783_Chip-Seq_NPCs_Mouse1.81930063
27CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76589232
28SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.75125579
29VDR_22108803_ChIP-Seq_LS180_Human1.75014528
30CDX2_19796622_ChIP-Seq_MESCs_Mouse1.74391268
31IGF1R_20145208_ChIP-Seq_DFB_Human1.71654321
32* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.70709829
33NANOG_18555785_Chip-Seq_ESCs_Mouse1.69536003
34ER_23166858_ChIP-Seq_MCF-7_Human1.68250453
35TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.66717397
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.66205872
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.64363765
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.63655645
39P300_19829295_ChIP-Seq_ESCs_Human1.63393075
40E2F1_18555785_Chip-Seq_ESCs_Mouse1.63374864
41EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.57808243
42EZH2_27304074_Chip-Seq_ESCs_Mouse1.57760765
43SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.56883880
44CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.55435905
45CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.54576174
46SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.53846278
47KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.53825691
48P300_18555785_Chip-Seq_ESCs_Mouse1.51645086
49SUZ12_18555785_Chip-Seq_ESCs_Mouse1.51052843
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.49432275
51EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.49313857
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.48889328
53ZNF274_21170338_ChIP-Seq_K562_Hela1.48709987
54P53_22387025_ChIP-Seq_ESCs_Mouse1.48358967
55EED_16625203_ChIP-ChIP_MESCs_Mouse1.47822783
56SMAD4_21799915_ChIP-Seq_A2780_Human1.46667584
57CMYC_18555785_Chip-Seq_ESCs_Mouse1.45335706
58RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44869849
59IRF8_22096565_ChIP-ChIP_GC-B_Human1.44562632
60RNF2_27304074_Chip-Seq_NSC_Mouse1.43535700
61NRF2_20460467_ChIP-Seq_MEFs_Mouse1.43288236
62NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.43288236
63SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.42395911
64BCAT_22108803_ChIP-Seq_LS180_Human1.42104709
65STAT3_18555785_Chip-Seq_ESCs_Mouse1.41961049
66SOX2_18555785_Chip-Seq_ESCs_Mouse1.41901698
67GATA1_22025678_ChIP-Seq_K562_Human1.41650209
68PCGF2_27294783_Chip-Seq_NPCs_Mouse1.40096932
69NMYC_18555785_Chip-Seq_ESCs_Mouse1.38237201
70EZH2_18974828_ChIP-Seq_MESCs_Mouse1.37008715
71RNF2_18974828_ChIP-Seq_MESCs_Mouse1.37008715
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.36874006
73TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.36566030
74PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35828420
75REST_18959480_ChIP-ChIP_MESCs_Mouse1.35622658
76JARID2_20075857_ChIP-Seq_MESCs_Mouse1.35290824
77RUNX1_27457419_Chip-Seq_LIVER_Mouse1.35258881
78KLF4_18555785_Chip-Seq_ESCs_Mouse1.34008170
79RUNX_20019798_ChIP-Seq_JUKART_Human1.33686965
80FOXM1_26456572_ChIP-Seq_MCF-7_Human1.33543785
81STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.32494800
82NR3C1_21868756_ChIP-Seq_MCF10A_Human1.32291884
83DROSHA_22980978_ChIP-Seq_HELA_Human1.31088639
84OCT4_18555785_Chip-Seq_ESCs_Mouse1.30234273
85EZH2_27294783_Chip-Seq_NPCs_Mouse1.29887835
86OCT4_21477851_ChIP-Seq_ESCs_Mouse1.29640496
87PRDM14_20953172_ChIP-Seq_ESCs_Human1.28698996
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.28234307
89SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.28152797
90TP53_16413492_ChIP-PET_HCT116_Human1.27798995
91MTF2_20144788_ChIP-Seq_MESCs_Mouse1.27352628
92PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.27144229
93RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25592722
94SMAD1_18555785_Chip-Seq_ESCs_Mouse1.25430917
95RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.25324299
96EZH2_27294783_Chip-Seq_ESCs_Mouse1.24095715
97* CBP_20019798_ChIP-Seq_JUKART_Human1.23849246
98* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23849246
99SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23478403
100SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.23109729
101ZFX_18555785_Chip-Seq_ESCs_Mouse1.22804847
102* CDX2_22108803_ChIP-Seq_LS180_Human1.22759453
103RNF2_27304074_Chip-Seq_ESCs_Mouse1.22166103
104NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.22000113
105CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.21447462
106TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.21349840
107SUZ12_27294783_Chip-Seq_ESCs_Mouse1.20439534
108PU1_27457419_Chip-Seq_LIVER_Mouse1.20321491
109STAT3_23295773_ChIP-Seq_U87_Human1.19835170
110TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18322330
111PIAS1_25552417_ChIP-Seq_VCAP_Human1.17908192
112TCF4_22108803_ChIP-Seq_LS180_Human1.17366898
113TCF4_23295773_ChIP-Seq_U87_Human1.17330498
114ESRRB_18555785_Chip-Seq_ESCs_Mouse1.16478111
115CTCF_18555785_Chip-Seq_ESCs_Mouse1.15875857
116MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14930750
117EWS_26573619_Chip-Seq_HEK293_Human1.14435321
118AHR_22903824_ChIP-Seq_MCF-7_Human1.11888651
119RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11654298
120ARNT_22903824_ChIP-Seq_MCF-7_Human1.11524654
121TP53_18474530_ChIP-ChIP_U2OS_Human1.11245804
122TAL1_26923725_Chip-Seq_HPCs_Mouse1.11127209
123NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10990525
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10985023
125* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.10385872
126RARB_27405468_Chip-Seq_BRAIN_Mouse1.10070553
127UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.10054270
128TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09913060
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09913060
130HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.09497895
131RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.08691146
132RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08230286
133PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07960033
134RUNX2_22187159_ChIP-Seq_PCA_Human1.07889476
135HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.07439072
136AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.06971290
137SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06318842
138CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05403797
139NANOG_19829295_ChIP-Seq_ESCs_Human1.03651323
140SOX2_19829295_ChIP-Seq_ESCs_Human1.03651323
141TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.02915374
142EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02697884
143KDM2B_26808549_Chip-Seq_REH_Human1.02328548
144AR_25329375_ChIP-Seq_VCAP_Human1.01682980
145CRX_20693478_ChIP-Seq_RETINA_Mouse1.01176976
146SOX9_26525672_Chip-Seq_HEART_Mouse0.99815283
147MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.97213920

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation6.06697090
2MP0003880_abnormal_central_pattern4.72131994
3MP0004859_abnormal_synaptic_plasticity3.78275490
4MP0001188_hyperpigmentation3.03383777
5MP0009046_muscle_twitch2.96058768
6MP0003635_abnormal_synaptic_transmissio2.87535111
7MP0004270_analgesia2.83429420
8MP0006054_spinal_hemorrhage2.79854783
9MP0005423_abnormal_somatic_nervous2.74382785
10MP0009745_abnormal_behavioral_response2.70255257
11MP0005409_darkened_coat_color2.67609270
12MP0003195_calcinosis2.55806756
13MP0002009_preneoplasia2.52189917
14MP0001486_abnormal_startle_reflex2.50875802
15MP0002064_seizures2.49706953
16MP0002272_abnormal_nervous_system2.49373787
17MP0001968_abnormal_touch/_nociception2.48812849
18MP0008877_abnormal_DNA_methylation2.47869288
19MP0006276_abnormal_autonomic_nervous2.46308892
20MP0002734_abnormal_mechanical_nocicepti2.37989228
21MP0002572_abnormal_emotion/affect_behav2.29347440
22MP0002063_abnormal_learning/memory/cond2.21898244
23MP0002166_altered_tumor_susceptibility2.11219752
24MP0001529_abnormal_vocalization2.08878385
25MP0002735_abnormal_chemical_nociception2.07171433
26MP0001501_abnormal_sleep_pattern2.04023573
27MP0005410_abnormal_fertilization1.97845365
28MP0001905_abnormal_dopamine_level1.95970033
29MP0003136_yellow_coat_color1.93124022
30MP0001440_abnormal_grooming_behavior1.93029846
31MP0002736_abnormal_nociception_after1.91402850
32MP0000427_abnormal_hair_cycle1.91251143
33MP0003763_abnormal_thymus_physiology1.77895084
34MP0004484_altered_response_of1.77447541
35MP0002067_abnormal_sensory_capabilities1.76900583
36MP0006292_abnormal_olfactory_placode1.67602148
37MP0001984_abnormal_olfaction1.65741363
38MP0001986_abnormal_taste_sensitivity1.63545479
39MP0005645_abnormal_hypothalamus_physiol1.62958629
40MP0001970_abnormal_pain_threshold1.61296936
41MP0009780_abnormal_chondrocyte_physiolo1.60852041
42MP0003724_increased_susceptibility_to1.59165345
43MP0000778_abnormal_nervous_system1.58812219
44MP0005646_abnormal_pituitary_gland1.58797015
45MP0004142_abnormal_muscle_tone1.58517203
46MP0004924_abnormal_behavior1.54921347
47MP0005386_behavior/neurological_phenoty1.54921347
48MP0003183_abnormal_peptide_metabolism1.54248960
49MP0005075_abnormal_melanosome_morpholog1.53897477
50MP0005551_abnormal_eye_electrophysiolog1.51260373
51MP0002822_catalepsy1.50216951
52MP0002733_abnormal_thermal_nociception1.48982517
53MP0002557_abnormal_social/conspecific_i1.47575292
54MP0002184_abnormal_innervation1.46583296
55MP0005671_abnormal_response_to1.43117349
56MP0005171_absent_coat_pigmentation1.42773706
57MP0002006_tumorigenesis1.42127379
58MP0003045_fibrosis1.38867710
59MP0003123_paternal_imprinting1.37714172
60MP0002928_abnormal_bile_duct1.36625682
61MP0001485_abnormal_pinna_reflex1.35424527
62MP0010678_abnormal_skin_adnexa1.35202261
63MP0003698_abnormal_male_reproductive1.33121418
64MP0003252_abnormal_bile_duct1.31625035
65MP0002882_abnormal_neuron_morphology1.30124004
66MP0002163_abnormal_gland_morphology1.29925221
67MP0000566_synostosis1.29916452
68MP0000920_abnormal_myelination1.27449673
69MP0003300_gastrointestinal_ulcer1.26565965
70MP0001835_abnormal_antigen_presentation1.24531971
71MP0004043_abnormal_pH_regulation1.24114536
72MP0009379_abnormal_foot_pigmentation1.23469884
73MP0004742_abnormal_vestibular_system1.22737989
74MP0002693_abnormal_pancreas_physiology1.22126886
75MP0000013_abnormal_adipose_tissue1.21627710
76MP0002277_abnormal_respiratory_mucosa1.20678594
77MP0002229_neurodegeneration1.20196377
78MP0008057_abnormal_DNA_replication1.19343612
79MP0000955_abnormal_spinal_cord1.19179475
80MP0010386_abnormal_urinary_bladder1.17609752
81MP0002752_abnormal_somatic_nervous1.17229191
82MP0005310_abnormal_salivary_gland1.16828214
83MP0002066_abnormal_motor_capabilities/c1.16156773
84MP0001963_abnormal_hearing_physiology1.15503852
85MP0003890_abnormal_embryonic-extraembry1.14095156
86MP0001800_abnormal_humoral_immune1.13409460
87MP0002638_abnormal_pupillary_reflex1.11634193
88MP0008569_lethality_at_weaning1.10886342
89MP0002160_abnormal_reproductive_system1.10255705
90MP0000465_gastrointestinal_hemorrhage1.09891322
91MP0003787_abnormal_imprinting1.09649189
92MP0000372_irregular_coat_pigmentation1.08745579
93MP0010234_abnormal_vibrissa_follicle1.07627789
94MP0002909_abnormal_adrenal_gland1.07463276
95MP0004885_abnormal_endolymph1.06574868
96MP0000383_abnormal_hair_follicle1.05647404
97MP0003633_abnormal_nervous_system1.05129672
98MP0000015_abnormal_ear_pigmentation1.04634307
99MP0001851_eye_inflammation1.03727696
100MP0003879_abnormal_hair_cell1.03304280
101MP0001177_atelectasis1.03192551
102MP0004133_heterotaxia1.00875870
103MP0002876_abnormal_thyroid_physiology1.00259584
104MP0001929_abnormal_gametogenesis0.98039797
105MP0005394_taste/olfaction_phenotype0.97626969
106MP0005499_abnormal_olfactory_system0.97626969
107MP0003718_maternal_effect0.97269188
108MP0005084_abnormal_gallbladder_morpholo0.96328145
109MP0010352_gastrointestinal_tract_polyps0.95808500
110MP0002168_other_aberrant_phenotype0.95688166
111MP0002210_abnormal_sex_determination0.95269196
112MP0003950_abnormal_plasma_membrane0.95048517
113MP0005379_endocrine/exocrine_gland_phen0.94309699
114MP0004811_abnormal_neuron_physiology0.93743966
115MP0008058_abnormal_DNA_repair0.93092258
116MP0002396_abnormal_hematopoietic_system0.91612786
117MP0004145_abnormal_muscle_electrophysio0.90401835
118MP0001299_abnormal_eye_distance/0.90071673
119MP0004215_abnormal_myocardial_fiber0.88835581
120MP0001765_abnormal_ion_homeostasis0.88439879
121MP0003941_abnormal_skin_development0.88228733
122MP0000371_diluted_coat_color0.87177659
123MP0002152_abnormal_brain_morphology0.85765253
124MP0009785_altered_susceptibility_to0.85320797
125MP0003632_abnormal_nervous_system0.84810001
126MP0003690_abnormal_glial_cell0.84424038
127MP0002723_abnormal_immune_serum0.84188760
128MP0003943_abnormal_hepatobiliary_system0.84158288
129MP0001502_abnormal_circadian_rhythm0.83570622
130MP0005253_abnormal_eye_physiology0.83037571
131MP0004883_abnormal_blood_vessel0.82305329
132MP0006072_abnormal_retinal_apoptosis0.82055987
133MP0000685_abnormal_immune_system0.82000627
134MP0002751_abnormal_autonomic_nervous0.81776080
135MP0008961_abnormal_basal_metabolism0.80827068
136MP0000026_abnormal_inner_ear0.79551036
137MP0008872_abnormal_physiological_respon0.79037160
138MP0002420_abnormal_adaptive_immunity0.78799354
139MP0001145_abnormal_male_reproductive0.78547069
140MP0005174_abnormal_tail_pigmentation0.78258926
141MP0005187_abnormal_penis_morphology0.77046698
142MP0002102_abnormal_ear_morphology0.76584583
143MP0001819_abnormal_immune_cell0.76313485
144MP0003631_nervous_system_phenotype0.76016233
145MP0002095_abnormal_skin_pigmentation0.75285513
146MP0001944_abnormal_pancreas_morphology0.75039313
147MP0003315_abnormal_perineum_morphology0.74422707
148MP0005000_abnormal_immune_tolerance0.74179959
149MP0003634_abnormal_glial_cell0.74167320
150MP0005220_abnormal_exocrine_pancreas0.72791421
151MP0000631_abnormal_neuroendocrine_gland0.72147919
152MP0002452_abnormal_antigen_presenting0.71980448
153MP0000653_abnormal_sex_gland0.70752423
154MP0004381_abnormal_hair_follicle0.69472868
155MP0000613_abnormal_salivary_gland0.67787625
156MP0008932_abnormal_embryonic_tissue0.66825017
157MP0005387_immune_system_phenotype0.66196146
158MP0001790_abnormal_immune_system0.66196146
159MP0009697_abnormal_copulation0.65519374
160MP0001191_abnormal_skin_condition0.65393854
161MP0003828_pulmonary_edema0.64799075

Predicted human phenotypes

RankGene SetZ-score
1Progressive external ophthalmoplegia (HP:0000590)4.97223064
2Focal motor seizures (HP:0011153)4.88541771
3Dynein arm defect of respiratory motile cilia (HP:0012255)4.00166405
4Absent/shortened dynein arms (HP:0200106)4.00166405
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.68953770
6Febrile seizures (HP:0002373)3.57891802
7Myokymia (HP:0002411)3.47513818
8Abnormal ciliary motility (HP:0012262)3.33277636
9Abnormal respiratory motile cilium physiology (HP:0012261)3.25648625
10Abnormal respiratory motile cilium morphology (HP:0005938)3.22295667
11Abnormal respiratory epithelium morphology (HP:0012253)3.22295667
12Focal seizures (HP:0007359)3.21904228
13Thyroiditis (HP:0100646)3.19716390
14Abnormality of T cell number (HP:0011839)3.12246442
15Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.11914801
16T lymphocytopenia (HP:0005403)3.10903917
17External ophthalmoplegia (HP:0000544)3.09049540
18Epileptic encephalopathy (HP:0200134)3.03364942
19Atonic seizures (HP:0010819)2.99715011
20Progressive inability to walk (HP:0002505)2.98575033
21Progressive cerebellar ataxia (HP:0002073)2.93841737
22Widely spaced teeth (HP:0000687)2.91347816
23Abnormality of the renal cortex (HP:0011035)2.85157101
24Broad-based gait (HP:0002136)2.84803358
25Renal cortical cysts (HP:0000803)2.79656214
26Fetal akinesia sequence (HP:0001989)2.72323800
27Stomatitis (HP:0010280)2.67873230
28Fair hair (HP:0002286)2.59939698
29Neoplasm of the tracheobronchial system (HP:0100552)2.58397572
30Absence seizures (HP:0002121)2.57889116
31Hypothermia (HP:0002045)2.57688856
32Birth length less than 3rd percentile (HP:0003561)2.57139367
33Dialeptic seizures (HP:0011146)2.55477168
34Medial flaring of the eyebrow (HP:0010747)2.55189669
35Carpal bone hypoplasia (HP:0001498)2.54363234
36Hematochezia (HP:0002573)2.53874238
37Papilledema (HP:0001085)2.53512277
38Papillary thyroid carcinoma (HP:0002895)2.48838736
39Gaze-evoked nystagmus (HP:0000640)2.48540113
40Generalized tonic-clonic seizures (HP:0002069)2.48358963
41Chromosomal breakage induced by crosslinking agents (HP:0003221)2.42600737
42Absent radius (HP:0003974)2.42305315
43Gait imbalance (HP:0002141)2.38061936
44Absent forearm bone (HP:0003953)2.36993257
45Aplasia involving forearm bones (HP:0009822)2.36993257
46Curly hair (HP:0002212)2.33261576
47Alveolar cell carcinoma (HP:0006519)2.31725034
48Abnormality of the labia minora (HP:0012880)2.30430737
49Generalized hypopigmentation of hair (HP:0011358)2.30392010
50Breast hypoplasia (HP:0003187)2.28455759
51Congenital primary aphakia (HP:0007707)2.26751780
52Thyroid carcinoma (HP:0002890)2.26479821
53Parakeratosis (HP:0001036)2.22301132
54Metaphyseal dysplasia (HP:0100255)2.15386093
55Chromsome breakage (HP:0040012)2.14886613
56Attenuation of retinal blood vessels (HP:0007843)2.14335026
57Retrobulbar optic neuritis (HP:0100654)2.11546850
58Optic neuritis (HP:0100653)2.11546850
59Genital tract atresia (HP:0001827)2.10978005
60Abnormal biliary tract morphology (HP:0012440)2.09809660
61Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.09538870
62Aplasia/Hypoplasia involving the musculature (HP:0001460)2.09531583
63Hypoglycemic seizures (HP:0002173)2.09377112
64Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.08898641
65Vaginal atresia (HP:0000148)2.08576456
66Stenosis of the external auditory canal (HP:0000402)2.05324298
67Dysmetria (HP:0001310)2.02915239
68Cerebral hypomyelination (HP:0006808)2.02322933
69Absent speech (HP:0001344)2.02036377
70Dyschromatopsia (HP:0007641)2.02026816
71Nephrogenic diabetes insipidus (HP:0009806)2.01881389
72Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.01310548
73Hemiparesis (HP:0001269)2.01150689
74Pheochromocytoma (HP:0002666)2.00692693
75Mutism (HP:0002300)2.00275791
76Visual hallucinations (HP:0002367)1.98913033
77Volvulus (HP:0002580)1.98444170
78Rhinitis (HP:0012384)1.98118198
79Septo-optic dysplasia (HP:0100842)1.96339818
80Decreased central vision (HP:0007663)1.96054110
81Duplicated collecting system (HP:0000081)1.95812541
82Aplasia/Hypoplasia of the earlobes (HP:0009906)1.95580934
83Pancreatic fibrosis (HP:0100732)1.94395429
84Protruding tongue (HP:0010808)1.93354995
85Anxiety (HP:0000739)1.93341035
86Large for gestational age (HP:0001520)1.92559104
87Optic nerve hypoplasia (HP:0000609)1.92126614
88True hermaphroditism (HP:0010459)1.90380498
89Intestinal atresia (HP:0011100)1.89284646
90Chronic diarrhea (HP:0002028)1.88859103
91Metabolic alkalosis (HP:0200114)1.88289572
92Abnormality of the corticospinal tract (HP:0002492)1.87525334
93Stomach cancer (HP:0012126)1.87256525
94Pancreatic cysts (HP:0001737)1.86377238
95Intention tremor (HP:0002080)1.85912293
96Limb dystonia (HP:0002451)1.85543163
97Ketoacidosis (HP:0001993)1.85451736
98Aplasia/hypoplasia of the uterus (HP:0008684)1.85039100
99Action tremor (HP:0002345)1.84813379
100Drooling (HP:0002307)1.84743301
101Excessive salivation (HP:0003781)1.84743301
102Supernumerary spleens (HP:0009799)1.84666690
103Acute necrotizing encephalopathy (HP:0006965)1.84441731
104Neuroendocrine neoplasm (HP:0100634)1.83581447
105Neoplasm of the adrenal cortex (HP:0100641)1.83087274
106Rectal fistula (HP:0100590)1.82472383
107Rectovaginal fistula (HP:0000143)1.82472383
108Horseshoe kidney (HP:0000085)1.82447161
109Autoimmune hemolytic anemia (HP:0001890)1.82204798
110Chronic hepatic failure (HP:0100626)1.81772763
111Subacute progressive viral hepatitis (HP:0006572)1.81705207
112Obstructive sleep apnea (HP:0002870)1.80935323
113Abnormality of eosinophils (HP:0001879)1.80911536
114Testicular atrophy (HP:0000029)1.80779244
115Severe combined immunodeficiency (HP:0004430)1.80536750
116Poor coordination (HP:0002370)1.80297510
117Dysdiadochokinesis (HP:0002075)1.78469338
118Abnormality of the renal medulla (HP:0100957)1.77048745
119Abnormality of the renal collecting system (HP:0004742)1.76739661
120Abnormality of the axillary hair (HP:0100134)1.76262437
121Abnormality of secondary sexual hair (HP:0009888)1.76262437
122Degeneration of the lateral corticospinal tracts (HP:0002314)1.76013051
123Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.76013051
124Hyperventilation (HP:0002883)1.75851562
125Optic disc pallor (HP:0000543)1.75537396
126Nephronophthisis (HP:0000090)1.75530568
127Retinal dysplasia (HP:0007973)1.75526144
128IgG deficiency (HP:0004315)1.75274408
129Abnormality of T cells (HP:0002843)1.74750112
130Severe visual impairment (HP:0001141)1.74391134
131Disproportionate short-trunk short stature (HP:0003521)1.74118441
132Menstrual irregularities (HP:0000858)1.73851929
133Furrowed tongue (HP:0000221)1.73836707
134Abnormality of the septum pellucidum (HP:0007375)1.72534930
135Albinism (HP:0001022)1.71780986
136Hip dysplasia (HP:0001385)1.71767876
137Abnormal hair whorl (HP:0010721)1.70448658
138Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.70045660
139Supranuclear gaze palsy (HP:0000605)1.69941292
140Hypokalemic alkalosis (HP:0001949)1.69205714
141Submucous cleft hard palate (HP:0000176)1.69025043
142Biliary tract neoplasm (HP:0100574)1.68171188
143Hamartoma of the eye (HP:0010568)1.67833336
144Congenital stationary night blindness (HP:0007642)1.67416405
145Short chin (HP:0000331)1.67118659
146Sleep apnea (HP:0010535)1.66934252
147Increased CSF protein (HP:0002922)1.66512453
148Oligodactyly (hands) (HP:0001180)1.65948439
149Neurofibrillary tangles (HP:0002185)1.65867349
150Chronic bronchitis (HP:0004469)1.65686623
151Molar tooth sign on MRI (HP:0002419)1.65571268
152Abnormality of midbrain morphology (HP:0002418)1.65571268
153Abnormal delayed hypersensitivity skin test (HP:0002963)1.65561873
154Pancreatic islet-cell hyperplasia (HP:0004510)1.65443811
155Aganglionic megacolon (HP:0002251)1.65195751
156Abnormality of the pancreatic islet cells (HP:0006476)1.62942503
157Abnormality of endocrine pancreas physiology (HP:0012093)1.62942503
158Aqueductal stenosis (HP:0002410)1.62624972
159Inability to walk (HP:0002540)1.62426585
160Tubular atrophy (HP:0000092)1.62422724
161Hemiplegia (HP:0002301)1.62288709
162Polydipsia (HP:0001959)1.62077245
163Abnormal drinking behavior (HP:0030082)1.62077245
164Hypoproteinemia (HP:0003075)1.61286664
165Abnormality of B cell number (HP:0010975)1.61125063
166Global brain atrophy (HP:0002283)1.60928534
167Keratoconjunctivitis (HP:0001096)1.60502293
168Genetic anticipation (HP:0003743)1.60379597
169Abnormal pancreas size (HP:0012094)1.59588322

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.90432076
2IRAK34.09226051
3ACVR1B3.11591575
4MARK12.93392873
5NTRK32.87633799
6PNCK2.85016089
7PLK42.84447027
8IRAK22.72483115
9CASK2.52512627
10TRIM282.50780694
11EPHA42.34414729
12PINK12.18224222
13IRAK12.10454484
14BMPR1B2.06943570
15NEK62.05298789
16TNIK2.01300600
17TAOK31.94558959
18MAP2K71.93829634
19ERBB31.89438847
20SRPK11.87810739
21RIPK41.86380616
22STK391.85341860
23AKT31.85281363
24MST41.82372707
25IRAK41.80372323
26NUAK11.66172262
27JAK11.65268593
28FGFR21.64498470
29ZAK1.62254121
30OXSR11.59512118
31MAP3K41.57716568
32NLK1.52539006
33PBK1.49130423
34TEC1.47070751
35NME11.43864036
36STK161.41484082
37PLK21.41414425
38FGFR31.40666548
39TXK1.38770431
40PAK31.37398777
41MAP4K21.33591610
42MKNK21.28683641
43MINK11.22715128
44BUB11.18989550
45LATS11.18448376
46CAMK2B1.16228789
47NTRK11.14028685
48VRK11.13762899
49TRPM71.13473659
50MAP3K91.13425171
51BMPR21.13146206
52LATS21.12337856
53PRPF4B1.08713629
54MAP3K141.02672674
55STK241.01581133
56STK31.00654494
57FER0.99257349
58EPHA30.96174627
59SIK30.95308094
60IKBKE0.94735675
61BRSK20.93787327
62CAMK2D0.93316425
63CAMK2A0.91876832
64PIK3CA0.91746671
65PLK30.90635366
66GRK70.90394385
67MUSK0.87550866
68GRK50.86900294
69STK380.86472636
70WEE10.85437759
71FES0.84357856
72EIF2AK20.83474458
73CDK190.83088490
74NTRK20.82893629
75MAPKAPK50.81184183
76ADRBK20.80810894
77PRKCG0.80492877
78PIK3CG0.79091171
79ITK0.78840524
80MAPK130.78019350
81MAP3K120.74928332
82PKN10.74308740
83PRKCQ0.73915237
84MAP2K40.73883608
85MAP3K20.73842798
86BCR0.73694906
87EIF2AK10.73185352
88CAMK2G0.72663578
89WNK10.72494743
90CAMKK20.72460806
91MAP2K60.72080239
92TTK0.71293995
93CDK50.70674970
94TGFBR20.70342243
95PTK2B0.70204746
96MELK0.69364604
97MKNK10.66560460
98BRD40.63072773
99TLK10.62655626
100TGFBR10.62427597
101WNK40.62147048
102GRK10.60894917
103CDK30.58654809
104PRKCE0.58301911
105SGK4940.58238050
106SGK2230.58238050
107RPS6KA40.57884487
108PLK10.57868519
109YES10.57314926
110BLK0.57172956
111LCK0.56735859
112HCK0.56063932
113STK38L0.55332270
114KSR10.55308661
115BRAF0.54616298
116IKBKB0.54323429
117EIF2AK30.52812427
118CDC70.52784423
119CAMK10.52629626
120SGK30.51638792
121MAPK100.51129206
122SYK0.50940765
123STK110.50753618
124TYK20.49390240
125PAK60.49178170
126CDC42BPA0.47439386
127ABL20.47142962
128UHMK10.46222829
129PDGFRB0.46015593
130CSNK1E0.45132516
131CSNK1G20.44384378
132PASK0.44176582
133KIT0.44059153
134WNK30.43823180
135EGFR0.43585807
136ADRBK10.43325126
137SGK10.43017244
138CSNK1G10.42606214
139DYRK1A0.42125786
140DAPK20.42078564
141DYRK20.41179956
142ABL10.40635172
143LYN0.40418377
144IGF1R0.40371718
145BTK0.40052766
146CSNK1A10.39962524
147CAMKK10.39947714
148PDK10.39461750
149MAPK70.38739059
150TNK20.37974004
151CDK60.37690633
152AURKA0.36802640
153FGR0.34620924
154CLK10.33807819
155SGK20.32194492
156ALK0.32121701
157CSNK1G30.32053254
158PRKACA0.31074739
159INSRR0.31002670
160PRKG10.30597545

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.93670180
2RNA polymerase_Homo sapiens_hsa030202.85719787
3Synaptic vesicle cycle_Homo sapiens_hsa047212.73977815
4Oxidative phosphorylation_Homo sapiens_hsa001902.49247510
5Phototransduction_Homo sapiens_hsa047442.43164557
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.37318244
7Circadian rhythm_Homo sapiens_hsa047102.34205464
8Glutamatergic synapse_Homo sapiens_hsa047242.23910512
9Morphine addiction_Homo sapiens_hsa050322.18955848
10GABAergic synapse_Homo sapiens_hsa047272.16145490
11Collecting duct acid secretion_Homo sapiens_hsa049662.15712385
12Amphetamine addiction_Homo sapiens_hsa050312.09810259
13Taste transduction_Homo sapiens_hsa047422.08969619
14Olfactory transduction_Homo sapiens_hsa047402.04336252
15Serotonergic synapse_Homo sapiens_hsa047262.00319875
16Circadian entrainment_Homo sapiens_hsa047131.90979906
17Long-term potentiation_Homo sapiens_hsa047201.88372232
18Huntingtons disease_Homo sapiens_hsa050161.85408424
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.84470519
20Parkinsons disease_Homo sapiens_hsa050121.79146932
21Fanconi anemia pathway_Homo sapiens_hsa034601.74948104
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.73354290
23Regulation of autophagy_Homo sapiens_hsa041401.61155008
24Alzheimers disease_Homo sapiens_hsa050101.59312018
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.56855285
26Ether lipid metabolism_Homo sapiens_hsa005651.56751034
27Salivary secretion_Homo sapiens_hsa049701.52437731
28Dopaminergic synapse_Homo sapiens_hsa047281.51299350
29Long-term depression_Homo sapiens_hsa047301.51102019
30SNARE interactions in vesicular transport_Homo sapiens_hsa041301.47363420
31Homologous recombination_Homo sapiens_hsa034401.46165693
32Insulin secretion_Homo sapiens_hsa049111.45668937
33Basal transcription factors_Homo sapiens_hsa030221.40017777
34Pyrimidine metabolism_Homo sapiens_hsa002401.38911992
35Nitrogen metabolism_Homo sapiens_hsa009101.38358315
36Purine metabolism_Homo sapiens_hsa002301.32818027
37Calcium signaling pathway_Homo sapiens_hsa040201.31911760
38Sphingolipid metabolism_Homo sapiens_hsa006001.31508548
39Cocaine addiction_Homo sapiens_hsa050301.30687378
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.30039235
41T cell receptor signaling pathway_Homo sapiens_hsa046601.29635032
42Vitamin B6 metabolism_Homo sapiens_hsa007501.29252963
43Cardiac muscle contraction_Homo sapiens_hsa042601.27925266
44Cholinergic synapse_Homo sapiens_hsa047251.26687423
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.25677569
46Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.24386157
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.19231150
48Oocyte meiosis_Homo sapiens_hsa041141.18783709
49Proteasome_Homo sapiens_hsa030501.11479484
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.10638375
51ABC transporters_Homo sapiens_hsa020101.10635656
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.09339742
53Gastric acid secretion_Homo sapiens_hsa049711.09167924
54Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.08208124
55Renin secretion_Homo sapiens_hsa049241.06151618
56Vibrio cholerae infection_Homo sapiens_hsa051101.04823432
57Platelet activation_Homo sapiens_hsa046111.03720035
58NOD-like receptor signaling pathway_Homo sapiens_hsa046211.03713152
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98807370
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.98377212
61Selenocompound metabolism_Homo sapiens_hsa004500.96046833
62Primary immunodeficiency_Homo sapiens_hsa053400.95772237
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.94320888
64Aldosterone synthesis and secretion_Homo sapiens_hsa049250.93243627
65Inositol phosphate metabolism_Homo sapiens_hsa005620.90928735
66Jak-STAT signaling pathway_Homo sapiens_hsa046300.89837532
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87389124
68Steroid biosynthesis_Homo sapiens_hsa001000.87027858
69FoxO signaling pathway_Homo sapiens_hsa040680.87024336
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.86902050
71Axon guidance_Homo sapiens_hsa043600.85805349
72mTOR signaling pathway_Homo sapiens_hsa041500.84350178
73Measles_Homo sapiens_hsa051620.83777029
74Linoleic acid metabolism_Homo sapiens_hsa005910.82392736
75Oxytocin signaling pathway_Homo sapiens_hsa049210.81476191
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.80689519
77cAMP signaling pathway_Homo sapiens_hsa040240.79505456
78B cell receptor signaling pathway_Homo sapiens_hsa046620.79202335
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78557824
80Mismatch repair_Homo sapiens_hsa034300.78502422
81Spliceosome_Homo sapiens_hsa030400.77756334
82Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.77101199
83Rheumatoid arthritis_Homo sapiens_hsa053230.76857864
84GnRH signaling pathway_Homo sapiens_hsa049120.76723758
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.76595715
86Graft-versus-host disease_Homo sapiens_hsa053320.75639743
87Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.74596732
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71796057
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70769295
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70734985
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.70265738
92DNA replication_Homo sapiens_hsa030300.69585591
93Melanogenesis_Homo sapiens_hsa049160.67531496
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.67134885
95Pancreatic secretion_Homo sapiens_hsa049720.65498109
96Osteoclast differentiation_Homo sapiens_hsa043800.65246947
97Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.63644086
98alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62665104
99Propanoate metabolism_Homo sapiens_hsa006400.62312179
100Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.61703935
101Ribosome_Homo sapiens_hsa030100.61556327
102NF-kappa B signaling pathway_Homo sapiens_hsa040640.61548716
103Hematopoietic cell lineage_Homo sapiens_hsa046400.61351326
104RNA degradation_Homo sapiens_hsa030180.61152858
105Arachidonic acid metabolism_Homo sapiens_hsa005900.61093417
106Vascular smooth muscle contraction_Homo sapiens_hsa042700.59829347
107TGF-beta signaling pathway_Homo sapiens_hsa043500.59820407
108Gap junction_Homo sapiens_hsa045400.57522110
109Fatty acid biosynthesis_Homo sapiens_hsa000610.55828402
110Chemokine signaling pathway_Homo sapiens_hsa040620.54644513
111Prolactin signaling pathway_Homo sapiens_hsa049170.54629667
112Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.54098304
113Butanoate metabolism_Homo sapiens_hsa006500.53589855
114Primary bile acid biosynthesis_Homo sapiens_hsa001200.53533002
115MAPK signaling pathway_Homo sapiens_hsa040100.52242942
116Dorso-ventral axis formation_Homo sapiens_hsa043200.52164580
117Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51472387
118Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50149203
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.49635085
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.49252945
121African trypanosomiasis_Homo sapiens_hsa051430.48915548
122Ras signaling pathway_Homo sapiens_hsa040140.48739097
123Mineral absorption_Homo sapiens_hsa049780.47711029
124Allograft rejection_Homo sapiens_hsa053300.47085056
125Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.47025501
126Nucleotide excision repair_Homo sapiens_hsa034200.47001481
127Autoimmune thyroid disease_Homo sapiens_hsa053200.46376745
128Legionellosis_Homo sapiens_hsa051340.45573369
129Tuberculosis_Homo sapiens_hsa051520.44596594
130Thyroid hormone synthesis_Homo sapiens_hsa049180.44108649
131Protein export_Homo sapiens_hsa030600.43116401
132Alcoholism_Homo sapiens_hsa050340.42921374
133Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42419763
134Ovarian steroidogenesis_Homo sapiens_hsa049130.41921072
135ErbB signaling pathway_Homo sapiens_hsa040120.41516326
136Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.41425149
137Sphingolipid signaling pathway_Homo sapiens_hsa040710.41211201
138Choline metabolism in cancer_Homo sapiens_hsa052310.40599712
139Phospholipase D signaling pathway_Homo sapiens_hsa040720.37675347
140Phagosome_Homo sapiens_hsa041450.37569232
141Type II diabetes mellitus_Homo sapiens_hsa049300.37261354
142RNA transport_Homo sapiens_hsa030130.37225219
143Non-homologous end-joining_Homo sapiens_hsa034500.36364750
144Phenylalanine metabolism_Homo sapiens_hsa003600.35874181
145Wnt signaling pathway_Homo sapiens_hsa043100.35806103
146Estrogen signaling pathway_Homo sapiens_hsa049150.34908212
147Type I diabetes mellitus_Homo sapiens_hsa049400.34509295
148cGMP-PKG signaling pathway_Homo sapiens_hsa040220.32959447

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