DNAJC11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.90623552
2DNA replication initiation (GO:0006270)4.66412151
3regulation of translational fidelity (GO:0006450)4.49908099
4DNA strand elongation involved in DNA replication (GO:0006271)4.45112390
5ribosome assembly (GO:0042255)4.43271486
6mitotic chromosome condensation (GO:0007076)4.42807026
7DNA deamination (GO:0045006)4.40402703
8mitotic metaphase plate congression (GO:0007080)4.37273232
9DNA strand elongation (GO:0022616)4.29605275
10DNA replication checkpoint (GO:0000076)4.26534389
11rRNA modification (GO:0000154)4.25650213
12telomere maintenance via semi-conservative replication (GO:0032201)4.24301057
13nucleobase biosynthetic process (GO:0046112)4.20059864
14ribosomal large subunit biogenesis (GO:0042273)4.13942828
15proteasome assembly (GO:0043248)4.09281665
16maturation of SSU-rRNA (GO:0030490)4.04732963
17ribosome biogenesis (GO:0042254)4.03133268
18protein complex localization (GO:0031503)4.00883131
19peptidyl-arginine omega-N-methylation (GO:0035247)3.99886707
20proline biosynthetic process (GO:0006561)3.89397179
21purine nucleobase biosynthetic process (GO:0009113)3.88241892
22DNA unwinding involved in DNA replication (GO:0006268)3.87789241
23ribonucleoprotein complex biogenesis (GO:0022613)3.82964179
24negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.79838511
25termination of RNA polymerase III transcription (GO:0006386)3.76124766
26transcription elongation from RNA polymerase III promoter (GO:0006385)3.76124766
27folic acid-containing compound biosynthetic process (GO:0009396)3.75497278
28telomere maintenance via telomere lengthening (GO:0010833)3.74441267
29Golgi transport vesicle coating (GO:0048200)3.74306587
30COPI coating of Golgi vesicle (GO:0048205)3.74306587
31heterochromatin organization (GO:0070828)3.72091283
32spliceosomal snRNP assembly (GO:0000387)3.71444581
33IMP biosynthetic process (GO:0006188)3.68634410
34metaphase plate congression (GO:0051310)3.68539329
35telomere maintenance via recombination (GO:0000722)3.67503605
36spliceosomal tri-snRNP complex assembly (GO:0000244)3.67274445
37histone arginine methylation (GO:0034969)3.67052359
38CENP-A containing nucleosome assembly (GO:0034080)3.65901031
39chromatin remodeling at centromere (GO:0031055)3.64833253
40folic acid metabolic process (GO:0046655)3.64315411
41DNA replication-dependent nucleosome organization (GO:0034723)3.64122596
42DNA replication-dependent nucleosome assembly (GO:0006335)3.64122596
43establishment of viral latency (GO:0019043)3.62728943
44regulation of double-strand break repair via homologous recombination (GO:0010569)3.61682196
45cellular protein complex localization (GO:0034629)3.59719469
46rRNA methylation (GO:0031167)3.58424147
47rRNA processing (GO:0006364)3.58212489
48protein localization to kinetochore (GO:0034501)3.57550219
49pore complex assembly (GO:0046931)3.54445288
50L-serine metabolic process (GO:0006563)3.53642376
51regulation of nuclear cell cycle DNA replication (GO:0033262)3.51461027
52maturation of 5.8S rRNA (GO:0000460)3.51061409
53rRNA metabolic process (GO:0016072)3.49020671
54pseudouridine synthesis (GO:0001522)3.48724429
55sister chromatid segregation (GO:0000819)3.48472524
56mitotic recombination (GO:0006312)3.48228445
57regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.47723152
58formation of translation preinitiation complex (GO:0001731)3.41275750
59anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.38961633
60kinetochore assembly (GO:0051382)3.37527394
61peptidyl-arginine methylation (GO:0018216)3.35826889
62peptidyl-arginine N-methylation (GO:0035246)3.35826889
63spliceosomal complex assembly (GO:0000245)3.35202041
64regulation of centriole replication (GO:0046599)3.34658203
65negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.31294794
66ribosomal small subunit biogenesis (GO:0042274)3.30075009
67transcription-coupled nucleotide-excision repair (GO:0006283)3.28138211
68DNA replication-independent nucleosome organization (GO:0034724)3.26674340
69DNA replication-independent nucleosome assembly (GO:0006336)3.26674340
70regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.25318537
71kinetochore organization (GO:0051383)3.24286362
72transcription elongation from RNA polymerase I promoter (GO:0006362)3.24200020
73regulation of mitotic spindle organization (GO:0060236)3.23847509
74positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.23168572
75mitochondrial DNA replication (GO:0006264)3.22946760
76nucleobase-containing small molecule interconversion (GO:0015949)3.22878717
77DNA duplex unwinding (GO:0032508)3.21872191
78regulation of RNA export from nucleus (GO:0046831)3.20132509
79mitotic nuclear envelope disassembly (GO:0007077)3.18856916
80termination of RNA polymerase I transcription (GO:0006363)3.18015580
81IMP metabolic process (GO:0046040)3.17761895
82establishment of chromosome localization (GO:0051303)3.15719299
83regulation of translational termination (GO:0006449)3.15674487
84deoxyribonucleotide biosynthetic process (GO:0009263)3.14923574
85negative regulation of mRNA processing (GO:0050686)3.09983479
86nucleotide-excision repair, DNA gap filling (GO:0006297)3.09439494
87transcription from RNA polymerase I promoter (GO:0006360)3.08660920
88protein localization to chromosome, centromeric region (GO:0071459)3.07967388
89histone exchange (GO:0043486)3.07096926
90establishment of integrated proviral latency (GO:0075713)3.05473092
91DNA-dependent DNA replication (GO:0006261)3.05349986
92NADH metabolic process (GO:0006734)3.05065294
93DNA geometric change (GO:0032392)3.04388675
94protein K6-linked ubiquitination (GO:0085020)3.04356358
957-methylguanosine mRNA capping (GO:0006370)3.03960580
96mitotic sister chromatid segregation (GO:0000070)3.03685363
97negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.03096567
98negative regulation of ligase activity (GO:0051352)3.03096567
99pentose-phosphate shunt (GO:0006098)3.02268506
100tRNA aminoacylation for protein translation (GO:0006418)3.00136128
101regulation of centrosome cycle (GO:0046605)3.00072411
102cellular component biogenesis (GO:0044085)2.99875491
103negative regulation of mitotic sister chromatid separation (GO:2000816)2.98682497
104negative regulation of mitotic sister chromatid segregation (GO:0033048)2.98682497
105negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.98682497
106negative regulation of sister chromatid segregation (GO:0033046)2.98682497
107negative regulation of chromosome segregation (GO:0051985)2.98397017
108NADPH regeneration (GO:0006740)2.98070201
109regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.96966465
110regulation of mitochondrial translation (GO:0070129)2.96818315
111spindle checkpoint (GO:0031577)2.95471458
112amino acid activation (GO:0043038)2.95320422
113tRNA aminoacylation (GO:0043039)2.95320422
114DNA damage response, detection of DNA damage (GO:0042769)2.95010925
115negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.94913837
116regulation of spindle organization (GO:0090224)2.94459588
117negative regulation of mRNA metabolic process (GO:1903312)2.94254106
118RNA capping (GO:0036260)2.94227045
1197-methylguanosine RNA capping (GO:0009452)2.94227045
120chromosome condensation (GO:0030261)2.93656346
121DNA topological change (GO:0006265)2.93563727
122ncRNA metabolic process (GO:0034660)2.91053064
123exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.90027881
124nuclear pore organization (GO:0006999)2.89899658
125translational initiation (GO:0006413)2.88435140
126ncRNA processing (GO:0034470)2.87662241
127nuclear envelope disassembly (GO:0051081)2.87620047
128membrane disassembly (GO:0030397)2.87620047
129positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.87527542
130mitotic spindle assembly checkpoint (GO:0007094)2.87375773
131spindle assembly checkpoint (GO:0071173)2.86906705
132RNA methylation (GO:0001510)2.86749197
133DNA replication (GO:0006260)2.86547719
134nucleosome disassembly (GO:0006337)2.85150760
135protein-DNA complex disassembly (GO:0032986)2.85150760
136mitochondrial fusion (GO:0008053)2.84270185
137RNA stabilization (GO:0043489)2.83758295
138mRNA stabilization (GO:0048255)2.83758295
139nuclear envelope organization (GO:0006998)2.81363565
140negative regulation of RNA splicing (GO:0033119)2.80630026
141tricarboxylic acid cycle (GO:0006099)2.79875748
142protein export from nucleus (GO:0006611)2.77782076
143DNA conformation change (GO:0071103)2.76773931
144regulation of nucleobase-containing compound transport (GO:0032239)2.74264154
145protein maturation by protein folding (GO:0022417)2.73785156
146pre-miRNA processing (GO:0031054)2.72014592
147proline metabolic process (GO:0006560)2.70231591
148serine family amino acid biosynthetic process (GO:0009070)2.69140538
149regulation of mammary gland epithelial cell proliferation (GO:0033599)2.67477008
150mRNA splicing, via spliceosome (GO:0000398)2.65606688
151RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.65606688
152nuclear envelope reassembly (GO:0031468)2.61870491
153mitotic nuclear envelope reassembly (GO:0007084)2.61870491
154planar cell polarity pathway involved in neural tube closure (GO:0090179)2.61560675
155RNA splicing, via transesterification reactions (GO:0000375)2.59483925
156positive regulation of chromosome segregation (GO:0051984)2.59482090
157glycolytic process (GO:0006096)2.58565024
158maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.56763487
159regulation of translational elongation (GO:0006448)2.56564887
160protein retention in ER lumen (GO:0006621)2.53128818
161mRNA transport (GO:0051028)2.52855867
162adherens junction assembly (GO:0034333)2.51214746
163rRNA transcription (GO:0009303)2.51026321
164mitotic sister chromatid cohesion (GO:0007064)2.50952763

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.85286085
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.49130579
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.78768084
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.77215107
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.66024566
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.47920221
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.31758344
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.25333793
9MYC_19079543_ChIP-ChIP_MESCs_Mouse3.22094774
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.19037947
11* ETS1_20019798_ChIP-Seq_JURKAT_Human3.16365882
12GABP_17652178_ChIP-ChIP_JURKAT_Human3.07697357
13MYC_18358816_ChIP-ChIP_MESCs_Mouse3.06683159
14* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.99634614
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.79148017
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.77220200
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.72343826
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.60711770
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.60171642
20XRN2_22483619_ChIP-Seq_HELA_Human2.39068928
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38677352
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.33402082
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.16455494
24VDR_23849224_ChIP-Seq_CD4+_Human2.14774829
25* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.14269533
26MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.12534225
27NANOG_18555785_ChIP-Seq_MESCs_Mouse2.12364248
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.12159722
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.05434262
30MYC_22102868_ChIP-Seq_BL_Human1.99523952
31FOXP3_21729870_ChIP-Seq_TREG_Human1.98878446
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.96958268
33ZNF263_19887448_ChIP-Seq_K562_Human1.94175967
34DCP1A_22483619_ChIP-Seq_HELA_Human1.92463181
35* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.91196781
36ELF1_17652178_ChIP-ChIP_JURKAT_Human1.89654299
37* YY1_21170310_ChIP-Seq_MESCs_Mouse1.89544860
38GABP_19822575_ChIP-Seq_HepG2_Human1.84565600
39AR_21909140_ChIP-Seq_LNCAP_Human1.83619467
40TTF2_22483619_ChIP-Seq_HELA_Human1.83281327
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.80688224
42CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.80640194
43* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80621802
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.79020108
45ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.74879633
46* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.74373843
47CIITA_25753668_ChIP-Seq_RAJI_Human1.73374294
48PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.67262159
49EGR1_19374776_ChIP-ChIP_THP-1_Human1.67141494
50POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.66023149
51KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.64281776
52CLOCK_20551151_ChIP-Seq_293T_Human1.62421892
53SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.61339697
54SRF_21415370_ChIP-Seq_HL-1_Mouse1.58220594
55POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.54527507
56NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.54298421
57TP63_17297297_ChIP-ChIP_HaCaT_Human1.54179701
58CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.50330796
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48275558
60PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43641295
61* KDM5A_27292631_Chip-Seq_BREAST_Human1.41443129
62FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.39499105
63TP63_19390658_ChIP-ChIP_HaCaT_Human1.37427480
64SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.37239675
65STAT3_1855785_ChIP-Seq_MESCs_Mouse1.36933231
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.35991764
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.34914576
68* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.34846006
69ELK3_25401928_ChIP-Seq_HUVEC_Human1.29992186
70DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.28514519
71ELK1_19687146_ChIP-ChIP_HELA_Human1.28205106
72KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.28147897
73KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.28147897
74KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.28147897
75VDR_21846776_ChIP-Seq_THP-1_Human1.27701618
76TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.26688681
77CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25259380
78ESR1_15608294_ChIP-ChIP_MCF-7_Human1.24986538
79TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.23081404
80* RACK7_27058665_Chip-Seq_MCF-7_Human1.22399068
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.22244153
82PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.19313980
83* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.18957099
84SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.18111702
85LXR_22292898_ChIP-Seq_THP-1_Human1.17292098
86* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.17016597
87ZFP281_18757296_ChIP-ChIP_E14_Mouse1.14691325
88* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.14000151
89PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13629780
90NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.13504158
91HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13015028
92MYC_18940864_ChIP-ChIP_HL60_Human1.12316917
93RARG_19884340_ChIP-ChIP_MEFs_Mouse1.11542370
94ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10793831
95DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.08999018
96* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06890346
97* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.06781478
98NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.06496999
99KLF4_18555785_ChIP-Seq_MESCs_Mouse1.05875332
100ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.05276071
101TCF3_18692474_ChIP-Seq_MEFs_Mouse1.05126250
102KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.04140668
103* CHD1_26751641_Chip-Seq_LNCaP_Human1.03535904
104* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03308826
105BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.03124324
106TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.02231028
107KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01648846
108* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01442842
109TBX5_21415370_ChIP-Seq_HL-1_Mouse1.00764170
110CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00381864
111NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.99812240
112CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.98783382
113NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.98257907
114TET1_21451524_ChIP-Seq_MESCs_Mouse0.98145015
115NOTCH1_21737748_ChIP-Seq_TLL_Human0.97750203
116NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.95398332
117* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.94721426
118* P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93490889
119SOX2_18692474_ChIP-Seq_MEFs_Mouse0.92956825
120ATF3_27146783_Chip-Seq_COLON_Human0.92899100
121KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.91671005
122CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.90754326
123NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.90651541
124YY1_22570637_ChIP-Seq_MALME-3M_Human0.88011350
125NANOG_21062744_ChIP-ChIP_HESCs_Human0.87110098
126* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.86712767
127OCT4_18692474_ChIP-Seq_MEFs_Mouse0.86380435
128TCF3_18692474_ChIP-Seq_MESCs_Mouse0.86353520
129SALL1_21062744_ChIP-ChIP_HESCs_Human0.86001300
130SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85617769
131* POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.84299582
132TFEB_21752829_ChIP-Seq_HELA_Human0.82583116
133ERG_20887958_ChIP-Seq_HPC-7_Mouse0.81657948
134SOX2_18692474_ChIP-Seq_MESCs_Mouse0.79962990
135SOX17_20123909_ChIP-Seq_XEN_Mouse0.79203097
136ELK1_22589737_ChIP-Seq_MCF10A_Human0.78969263
137NANOG_16153702_ChIP-ChIP_HESCs_Human0.78702400

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.75828435
2MP0003111_abnormal_nucleus_morphology4.97059041
3MP0010094_abnormal_chromosome_stability4.44123295
4MP0004957_abnormal_blastocyst_morpholog4.19894589
5MP0008058_abnormal_DNA_repair3.88697781
6MP0003077_abnormal_cell_cycle3.82765888
7MP0008057_abnormal_DNA_replication3.47948373
8MP0003718_maternal_effect3.24369550
9MP0003705_abnormal_hypodermis_morpholog3.23099414
10MP0008932_abnormal_embryonic_tissue3.03980017
11MP0003806_abnormal_nucleotide_metabolis2.99444205
12MP0004233_abnormal_muscle_weight2.35564828
13MP0008877_abnormal_DNA_methylation2.34843402
14MP0006292_abnormal_olfactory_placode2.26186431
15MP0008007_abnormal_cellular_replicative2.23034020
16MP0001730_embryonic_growth_arrest2.22325860
17MP0000566_synostosis2.18900965
18MP0003566_abnormal_cell_adhesion2.10512774
19MP0002877_abnormal_melanocyte_morpholog2.08438699
20MP0003786_premature_aging1.95619930
21MP0005076_abnormal_cell_differentiation1.91139641
22MP0000751_myopathy1.87640318
23MP0000350_abnormal_cell_proliferation1.86588094
24MP0003941_abnormal_skin_development1.85770406
25MP0001849_ear_inflammation1.85295903
26MP0003315_abnormal_perineum_morphology1.84627414
27MP0003123_paternal_imprinting1.75362162
28MP0001672_abnormal_embryogenesis/_devel1.75304623
29MP0005380_embryogenesis_phenotype1.75304623
30MP0003646_muscle_fatigue1.73158499
31MP0004185_abnormal_adipocyte_glucose1.64981646
32MP0005257_abnormal_intraocular_pressure1.61747224
33MP0002102_abnormal_ear_morphology1.56672614
34MP0004272_abnormal_basement_membrane1.55826742
35MP0005623_abnormal_meninges_morphology1.50028041
36MP0002085_abnormal_embryonic_tissue1.49892204
37MP0001697_abnormal_embryo_size1.47114901
38MP0002210_abnormal_sex_determination1.45288184
39MP0004133_heterotaxia1.44343517
40MP0005451_abnormal_body_composition1.44164424
41MP0002080_prenatal_lethality1.43763217
42MP0003984_embryonic_growth_retardation1.42565374
43MP0008260_abnormal_autophagy1.39685611
44MP0002088_abnormal_embryonic_growth/wei1.39182104
45MP0003890_abnormal_embryonic-extraembry1.38046870
46MP0001346_abnormal_lacrimal_gland1.36589683
47MP0006035_abnormal_mitochondrial_morpho1.35957762
48MP0000579_abnormal_nail_morphology1.35292656
49MP0001661_extended_life_span1.34307366
50MP0010234_abnormal_vibrissa_follicle1.31075760
51MP0000313_abnormal_cell_death1.29065077
52MP0010030_abnormal_orbit_morphology1.27620714
53MP0008438_abnormal_cutaneous_collagen1.25891064
54MP0002796_impaired_skin_barrier1.24398387
55MP0003567_abnormal_fetal_cardiomyocyte1.24182082
56MP0002084_abnormal_developmental_patter1.23004590
57MP0002160_abnormal_reproductive_system1.21635901
58MP0001145_abnormal_male_reproductive1.19156179
59MP0009840_abnormal_foam_cell1.18968321
60MP0000747_muscle_weakness1.16016585
61MP0005330_cardiomyopathy1.15862056
62MP0004087_abnormal_muscle_fiber1.14498384
63MP0003121_genomic_imprinting1.12974182
64MP0005389_reproductive_system_phenotype1.12341962
65MP0000678_abnormal_parathyroid_gland1.12222812
66MP0000653_abnormal_sex_gland1.11934892
67MP0010630_abnormal_cardiac_muscle1.11813617
68MP0005395_other_phenotype1.11680177
69MP0004858_abnormal_nervous_system1.11548503
70MP0004197_abnormal_fetal_growth/weight/1.08833033
71MP0003385_abnormal_body_wall1.08253202
72MP0001119_abnormal_female_reproductive1.07839602
73MP0001727_abnormal_embryo_implantation1.07738058
74MP0002086_abnormal_extraembryonic_tissu1.07467317
75MP0003937_abnormal_limbs/digits/tail_de1.07337397
76MP0001929_abnormal_gametogenesis1.06942828
77MP0000733_abnormal_muscle_development1.05618298
78MP0003119_abnormal_digestive_system1.05588638
79MP0000762_abnormal_tongue_morphology1.05337436
80MP0002111_abnormal_tail_morphology1.04818917
81MP0006036_abnormal_mitochondrial_physio1.04660616
82MP0000759_abnormal_skeletal_muscle1.04235701
83MP0000749_muscle_degeneration1.04060735
84MP0000490_abnormal_crypts_of1.04033448
85MP0000358_abnormal_cell_content/1.00389383
86MP0002019_abnormal_tumor_incidence1.00383108
87MP0001919_abnormal_reproductive_system1.00357874
88MP0003186_abnormal_redox_activity0.98714425
89MP0001915_intracranial_hemorrhage0.98321160
90MP0009703_decreased_birth_body0.97637434
91MP0002089_abnormal_postnatal_growth/wei0.97383214
92MP0008789_abnormal_olfactory_epithelium0.97201971
93MP0000467_abnormal_esophagus_morphology0.95364017
94MP0001293_anophthalmia0.94603122
95MP0000003_abnormal_adipose_tissue0.93930550
96MP0002060_abnormal_skin_morphology0.93670199
97MP0002396_abnormal_hematopoietic_system0.93607071
98MP0003453_abnormal_keratinocyte_physiol0.91808566
99MP0003221_abnormal_cardiomyocyte_apopto0.90243249
100MP0009672_abnormal_birth_weight0.88743555
101MP0001299_abnormal_eye_distance/0.88111534
102MP0005377_hearing/vestibular/ear_phenot0.87427218
103MP0003878_abnormal_ear_physiology0.87427218
104MP0000428_abnormal_craniofacial_morphol0.86812313
105MP0000537_abnormal_urethra_morphology0.86807130
106MP0010307_abnormal_tumor_latency0.86542275
107MP0002269_muscular_atrophy0.86195217
108MP0003115_abnormal_respiratory_system0.84986706
109MP0010352_gastrointestinal_tract_polyps0.84756119
110MP0003011_delayed_dark_adaptation0.82527710
111MP0003699_abnormal_female_reproductive0.82527227
112MP0005670_abnormal_white_adipose0.81960013
113MP0001286_abnormal_eye_development0.80147820
114MP0002092_abnormal_eye_morphology0.80035976
115MP0009697_abnormal_copulation0.79745164
116MP0002249_abnormal_larynx_morphology0.78924002
117MP0003938_abnormal_ear_development0.78871321
118MP0005266_abnormal_metabolism0.77890361
119MP0004808_abnormal_hematopoietic_stem0.76752957
120MP0005384_cellular_phenotype0.74999327
121MP0005666_abnormal_adipose_tissue0.72403323
122MP0000750_abnormal_muscle_regeneration0.72157336
123MP0002132_abnormal_respiratory_system0.71515421
124MP0009278_abnormal_bone_marrow0.70870167
125MP0009053_abnormal_anal_canal0.68964105
126MP0004264_abnormal_extraembryonic_tissu0.67619320
127MP0005394_taste/olfaction_phenotype0.67231985
128MP0005499_abnormal_olfactory_system0.67231985
129MP0003861_abnormal_nervous_system0.66873189
130MP0003942_abnormal_urinary_system0.66454349
131MP0002127_abnormal_cardiovascular_syste0.66306995
132MP0000432_abnormal_head_morphology0.66102574
133MP0005501_abnormal_skin_physiology0.65859737
134MP0003091_abnormal_cell_migration0.63666863
135MP0001216_abnormal_epidermal_layer0.63503165
136MP0005075_abnormal_melanosome_morpholog0.62913594
137MP0001764_abnormal_homeostasis0.61132704
138MP0004147_increased_porphyrin_level0.61075919
139MP0002277_abnormal_respiratory_mucosa0.60598289
140MP0009379_abnormal_foot_pigmentation0.59032382
141MP0000049_abnormal_middle_ear0.59009524
142MP0003136_yellow_coat_color0.58799473
143MP0005621_abnormal_cell_physiology0.58240220
144MP0002161_abnormal_fertility/fecundity0.58179977
145MP0002697_abnormal_eye_size0.57413339
146MP0001529_abnormal_vocalization0.55798276
147MP0003787_abnormal_imprinting0.54977863
148MP0000703_abnormal_thymus_morphology0.54835050

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.96002158
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.93685588
3Chromsome breakage (HP:0040012)4.62614001
4Breast hypoplasia (HP:0003187)4.56604729
5Reticulocytopenia (HP:0001896)3.87387291
6Oral leukoplakia (HP:0002745)3.80909427
7Duplicated collecting system (HP:0000081)3.80399028
8Patellar aplasia (HP:0006443)3.66973812
9Abnormality of the preputium (HP:0100587)3.50624026
10Cholecystitis (HP:0001082)3.50456255
11Abnormal gallbladder physiology (HP:0012438)3.50456255
12Cerebral hypomyelination (HP:0006808)3.50176481
13Meckel diverticulum (HP:0002245)3.49790353
14Aplasia/Hypoplasia of the patella (HP:0006498)3.46150909
15Progressive external ophthalmoplegia (HP:0000590)3.36530622
16Abnormality of the renal collecting system (HP:0004742)3.27349997
17Abnormality of the ileum (HP:0001549)3.24332961
18Absent radius (HP:0003974)3.23345763
19Carpal bone hypoplasia (HP:0001498)3.22983773
20Abnormality of pyrimidine metabolism (HP:0004353)3.21742020
21Hyperacusis (HP:0010780)3.17477467
22Ragged-red muscle fibers (HP:0003200)3.12987026
23Aplasia involving forearm bones (HP:0009822)3.11223951
24Absent forearm bone (HP:0003953)3.11223951
25Abnormality of chromosome stability (HP:0003220)3.08517786
26Aplasia/Hypoplasia of the uvula (HP:0010293)3.05991941
27Premature ovarian failure (HP:0008209)3.00633878
28Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.91627329
29Abnormality of the labia minora (HP:0012880)2.89714003
30Insomnia (HP:0100785)2.83198169
31Macrocytic anemia (HP:0001972)2.78342770
32Centrally nucleated skeletal muscle fibers (HP:0003687)2.76042003
33Increased nuchal translucency (HP:0010880)2.75904130
34Abnormality of glycolysis (HP:0004366)2.75520616
35Increased serum pyruvate (HP:0003542)2.75520616
36Absent thumb (HP:0009777)2.74223444
37Horseshoe kidney (HP:0000085)2.73975307
38Rough bone trabeculation (HP:0100670)2.72883115
39Impulsivity (HP:0100710)2.70368745
40Distal lower limb amyotrophy (HP:0008944)2.69576999
41Selective tooth agenesis (HP:0001592)2.68022800
42Microvesicular hepatic steatosis (HP:0001414)2.67204898
43Abnormality of cells of the erythroid lineage (HP:0012130)2.64339410
44Increased connective tissue (HP:0009025)2.64143996
45Increased serum lactate (HP:0002151)2.57191907
46Ureteral duplication (HP:0000073)2.56296706
47Triphalangeal thumb (HP:0001199)2.52471544
48Medulloblastoma (HP:0002885)2.50536623
49Ependymoma (HP:0002888)2.49009315
50Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.48527458
51Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.47712960
52Spastic diplegia (HP:0001264)2.46923017
53Secondary amenorrhea (HP:0000869)2.45979953
54Bone marrow hypocellularity (HP:0005528)2.45737182
55Abnormal number of erythroid precursors (HP:0012131)2.44455431
56Achilles tendon contracture (HP:0001771)2.41658613
57Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.40898757
58Abnormality of alanine metabolism (HP:0010916)2.40898757
59Hyperalaninemia (HP:0003348)2.40898757
60Premature rupture of membranes (HP:0001788)2.40364070
61Ulnar bowing (HP:0003031)2.39858620
623-Methylglutaconic aciduria (HP:0003535)2.35156640
63Duodenal stenosis (HP:0100867)2.33882655
64Small intestinal stenosis (HP:0012848)2.33882655
65Aplasia/Hypoplasia of the earlobes (HP:0009906)2.33686923
66Cortical dysplasia (HP:0002539)2.32535631
67Deviation of the thumb (HP:0009603)2.30508560
68Proximal placement of thumb (HP:0009623)2.30369553
69Decreased activity of mitochondrial respiratory chain (HP:0008972)2.29188114
70Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.29188114
71Pallor (HP:0000980)2.28120838
72Abnormality of DNA repair (HP:0003254)2.27717430
73Neoplasm of the pancreas (HP:0002894)2.27492200
74Overriding aorta (HP:0002623)2.26086308
75Ectopic kidney (HP:0000086)2.25768341
76Megaloblastic anemia (HP:0001889)2.24621016
77Abnormal number of incisors (HP:0011064)2.23329267
78Reticulocytosis (HP:0001923)2.22869521
79Tracheoesophageal fistula (HP:0002575)2.20113311
80External ophthalmoplegia (HP:0000544)2.19688592
81Abnormality of the Achilles tendon (HP:0005109)2.15268386
82Lower limb amyotrophy (HP:0007210)2.15144406
83Aplasia/Hypoplasia involving the musculature (HP:0001460)2.14957587
84Sloping forehead (HP:0000340)2.13783292
85Increased hepatocellular lipid droplets (HP:0006565)2.13406141
86Breast aplasia (HP:0100783)2.12394925
87Trismus (HP:0000211)2.11866903
88Protrusio acetabuli (HP:0003179)2.11754838
89Abnormality of the calcaneus (HP:0008364)2.11121766
90Myopathic facies (HP:0002058)2.10479422
91Premature graying of hair (HP:0002216)2.10332354
92Progressive muscle weakness (HP:0003323)2.09440184
93Hepatocellular necrosis (HP:0001404)2.08274974
94Agnosia (HP:0010524)2.07795516
95Supernumerary spleens (HP:0009799)2.06850828
96Aplasia/Hypoplasia of the breasts (HP:0010311)2.06670129
97Multiple enchondromatosis (HP:0005701)2.05629193
98Abnormality of the carotid arteries (HP:0005344)2.05168104
99Increased CSF lactate (HP:0002490)2.04106776
100Shoulder girdle muscle weakness (HP:0003547)2.03858990
101Gout (HP:0001997)2.03730363
102Abnormal trabecular bone morphology (HP:0100671)2.03563730
103Abnormality of serum amino acid levels (HP:0003112)2.01212582
104Hepatic necrosis (HP:0002605)2.00761734
105Hyperglycinemia (HP:0002154)2.00534938
106Lipid accumulation in hepatocytes (HP:0006561)1.99168475
107Rhabdomyosarcoma (HP:0002859)1.99102248
108Cellular immunodeficiency (HP:0005374)1.98647920
109Renal duplication (HP:0000075)1.97109032
110Abnormality of pain sensation (HP:0010832)1.97060702
111Impaired pain sensation (HP:0007328)1.97060702
112Distal lower limb muscle weakness (HP:0009053)1.96470091
113Colon cancer (HP:0003003)1.95847867
114Hyperglycinuria (HP:0003108)1.94688802
115Abnormality of the duodenum (HP:0002246)1.94581782
116Distal upper limb amyotrophy (HP:0007149)1.93931866
117Upper limb amyotrophy (HP:0009129)1.93931866
118Long palpebral fissure (HP:0000637)1.93662216
119Calcaneovalgus deformity (HP:0001848)1.93536410
120Acute necrotizing encephalopathy (HP:0006965)1.92182681
121Pancytopenia (HP:0001876)1.92012534
122Abnormality of the salivary glands (HP:0010286)1.90795652
123Exercise intolerance (HP:0003546)1.90422157
124Shallow orbits (HP:0000586)1.90242259
125Clubbing of toes (HP:0100760)1.89746323
126Aplasia/Hypoplasia of the sacrum (HP:0008517)1.89639787
127Short thumb (HP:0009778)1.89391721
128Proximal tubulopathy (HP:0000114)1.89130166
129Mitochondrial inheritance (HP:0001427)1.89005891
130Breech presentation (HP:0001623)1.88067574
131Hypoplasia of the capital femoral epiphysis (HP:0003090)1.87873435
132Pelvic girdle muscle weakness (HP:0003749)1.87779453
133Cholelithiasis (HP:0001081)1.87290200
134Overlapping toe (HP:0001845)1.86652119
135CNS hypomyelination (HP:0003429)1.86500829
136High anterior hairline (HP:0009890)1.85876954
137Spinal rigidity (HP:0003306)1.85669923
138Aplastic anemia (HP:0001915)1.85464130
139Myelodysplasia (HP:0002863)1.84340354
140Ankyloglossia (HP:0010296)1.82559929
141Vertebral compression fractures (HP:0002953)1.82427848
142Deformed tarsal bones (HP:0008119)1.82293638
143Abnormality of reticulocytes (HP:0004312)1.80332368
144Pendular nystagmus (HP:0012043)1.79923844
145Back pain (HP:0003418)1.78750219
146Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.78543491
147Lactic acidosis (HP:0003128)1.78511444
148Disproportionate tall stature (HP:0001519)1.74433117
149Duplication of thumb phalanx (HP:0009942)1.73112269
150Limb-girdle muscle atrophy (HP:0003797)1.68581445
151Elfin facies (HP:0004428)1.68374668
152Abnormality of the umbilical cord (HP:0010881)1.67664546
153Patellar dislocation (HP:0002999)1.66440949
154Nemaline bodies (HP:0003798)1.62916494
155Short nail (HP:0001799)1.62597237
156Pointed chin (HP:0000307)1.62467649
157Abnormality of oral frenula (HP:0000190)1.62438618
158Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.61237545
159Dysmetric saccades (HP:0000641)1.60480125
160Generalized amyotrophy (HP:0003700)1.60272382
161Progressive hearing impairment (HP:0001730)1.58863932
162Orthostatic hypotension (HP:0001278)1.58758418
163Nonimmune hydrops fetalis (HP:0001790)1.57828776
164Broad distal phalanx of finger (HP:0009836)1.57302683
165Testicular atrophy (HP:0000029)1.57231661
166Abnormal gallbladder morphology (HP:0012437)1.56307695
167Difficulty climbing stairs (HP:0003551)1.56229375
168Pterygium (HP:0001059)1.56159591
169Exercise-induced muscle cramps (HP:0003710)1.55692199
170Trigonocephaly (HP:0000243)1.54353575
171Abnormalities of placenta or umbilical cord (HP:0001194)1.54039482
172Septate vagina (HP:0001153)1.52824282
173Sparse lateral eyebrow (HP:0005338)1.52414110
174Choanal stenosis (HP:0000452)1.51880254
175Partial duplication of thumb phalanx (HP:0009944)1.51804666
176Abnormality of cochlea (HP:0000375)1.51508616
177Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.51367347
178Absent epiphyses (HP:0010577)1.51367347
179Muscle fiber inclusion bodies (HP:0100299)1.50517384
180Abnormality of the hip-girdle musculature (HP:0001445)1.50362637
181Abnormality of the musculature of the pelvis (HP:0001469)1.50362637
182Turricephaly (HP:0000262)1.49886843
183Abnormality of the gallbladder (HP:0005264)1.49661947

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.12841092
2PLK44.65876490
3WEE13.65420360
4TTK3.51402283
5SMG13.30682902
6STK163.15613025
7TRIB33.10715491
8EIF2AK13.08239653
9SRPK13.01690615
10EPHA22.81165479
11ZAK2.79615190
12CDC72.75211293
13ICK2.44039213
14TSSK62.25217942
15TLK12.24180319
16VRK22.21301231
17IRAK32.09886443
18PLK11.99433657
19STK38L1.92562257
20NEK21.78596914
21TTN1.77649611
22TESK21.69384165
23ATR1.64085574
24AURKA1.61054791
25RPS6KB21.60195934
26NEK11.57193301
27PRPF4B1.55037788
28CHEK21.50743181
29MST1R1.49100713
30NME21.49087586
31CDK71.48686843
32AURKB1.46969991
33VRK11.46703784
34PNCK1.43755718
35SIK11.42872980
36DYRK31.38894087
37PLK31.35017976
38MKNK11.34190502
39MARK11.33923331
40PDGFRA1.33067530
41ACVR1B1.31866421
42FGFR41.31301414
43EIF2AK31.30052884
44MKNK21.28348480
45MAP3K81.26768686
46BRSK21.24396017
47LATS21.21639694
48BCKDK1.18902951
49BRAF1.11906327
50RIPK11.10865654
51CHEK11.10808323
52DYRK21.09794128
53SCYL21.09231663
54STK41.08965932
55PBK1.08642889
56MAPKAPK31.06084845
57PKN21.05688018
58BRD41.02905724
59CDK41.02823363
60BRSK11.02632408
61NME11.01853547
62EIF2AK20.97483151
63CDK80.96617942
64PRKD30.95782213
65PRKCI0.95045368
66NTRK10.89251843
67PASK0.85823122
68LMTK20.83171161
69PAK40.82626950
70KSR20.81120707
71ARAF0.79810827
72PTK20.79635406
73TESK10.79246961
74MET0.76977849
75CDK120.76090740
76ATM0.74950767
77PAK10.74915531
78KDR0.74787937
79CDK20.74410952
80EEF2K0.73408404
81IRAK20.73238921
82PIM20.72540758
83CDK60.72229618
84CDK90.70230571
85AKT30.69716694
86PAK20.69418988
87BLK0.69077648
88CLK10.66268150
89PDK20.64611551
90ERBB40.64428914
91IRAK40.63451326
92TAOK20.63249914
93CSNK2A20.62554342
94LRRK20.61726186
95ALK0.61476028
96CDK10.60829189
97CSNK2A10.59309797
98STK100.57622633
99MAP3K110.56708164
100CSNK1E0.56118978
101BMX0.54586495
102CAMK1D0.54027069
103IRAK10.53529629
104CDK11A0.51896604
105CDK150.50027264
106CDK180.48079373
107PTK60.46869306
108ERN10.46254459
109AKT20.44807631
110RPS6KA50.44503125
111CDK140.43408551
112DAPK10.42375295
113PINK10.41860849
114TAF10.41439958
115TGFBR10.38799341
116RAF10.37730052
117MAP2K20.35853024
118CCNB10.35401783
119LATS10.34948090
120FGFR10.34758464
121CDK190.33021924
122ABL20.32789355
123OBSCN0.32697509
124SIK30.30465195
125PDK30.30016203
126PDK40.30016203
127PRKDC0.29177826
128CAMK1G0.28475386
129STK30.26925946
130RPS6KA40.25046110
131LIMK10.24240503
132MTOR0.22424990
133MELK0.22424090
134GRK10.21691121
135PIM10.19315975
136CSNK1D0.16922000
137MAPK140.16757521
138GSK3B0.16452841
139STK240.15702212
140MAPK110.15656280
141MAP3K100.14315270
142YES10.12118312
143MAPK90.11989056

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.31241281
2Mismatch repair_Homo sapiens_hsa034303.76332524
3RNA polymerase_Homo sapiens_hsa030203.73817591
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.53502275
5Proteasome_Homo sapiens_hsa030503.51379498
6Ribosome_Homo sapiens_hsa030103.08376427
7Spliceosome_Homo sapiens_hsa030403.02610407
8One carbon pool by folate_Homo sapiens_hsa006702.99382137
9Homologous recombination_Homo sapiens_hsa034402.98005815
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.85780677
11Fanconi anemia pathway_Homo sapiens_hsa034602.69368722
12RNA transport_Homo sapiens_hsa030132.67713481
13Pyrimidine metabolism_Homo sapiens_hsa002402.64974536
14Nucleotide excision repair_Homo sapiens_hsa034202.55381148
15Base excision repair_Homo sapiens_hsa034102.39520982
16Cell cycle_Homo sapiens_hsa041102.17547730
17Basal transcription factors_Homo sapiens_hsa030221.80951245
18Non-homologous end-joining_Homo sapiens_hsa034501.79252064
19RNA degradation_Homo sapiens_hsa030181.68125939
20Vitamin B6 metabolism_Homo sapiens_hsa007501.52533933
21Central carbon metabolism in cancer_Homo sapiens_hsa052301.47833317
22Cysteine and methionine metabolism_Homo sapiens_hsa002701.47473856
23Purine metabolism_Homo sapiens_hsa002301.43431407
24Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.40504242
25Cyanoamino acid metabolism_Homo sapiens_hsa004601.40283499
262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.39245747
27mRNA surveillance pathway_Homo sapiens_hsa030151.33160427
28Thyroid cancer_Homo sapiens_hsa052161.30839442
29Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.26260587
30Biosynthesis of amino acids_Homo sapiens_hsa012301.25601192
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.23629897
32p53 signaling pathway_Homo sapiens_hsa041151.21195705
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.19566759
34Oxidative phosphorylation_Homo sapiens_hsa001901.13780204
35Parkinsons disease_Homo sapiens_hsa050121.07722924
36Systemic lupus erythematosus_Homo sapiens_hsa053221.06119684
37Bladder cancer_Homo sapiens_hsa052191.05206502
38Huntingtons disease_Homo sapiens_hsa050161.04880263
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.00966882
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00009122
41Epstein-Barr virus infection_Homo sapiens_hsa051690.99748351
42Folate biosynthesis_Homo sapiens_hsa007900.99558158
43Carbon metabolism_Homo sapiens_hsa012000.99534911
44Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.98372744
45Pentose phosphate pathway_Homo sapiens_hsa000300.93290984
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.92390852
47Chronic myeloid leukemia_Homo sapiens_hsa052200.91277935
48Steroid biosynthesis_Homo sapiens_hsa001000.90765301
49Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.90636273
50Arginine biosynthesis_Homo sapiens_hsa002200.90114446
51Selenocompound metabolism_Homo sapiens_hsa004500.89386485
52Glutathione metabolism_Homo sapiens_hsa004800.88879427
53Adherens junction_Homo sapiens_hsa045200.85410158
54Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.82954341
55Arginine and proline metabolism_Homo sapiens_hsa003300.81011013
56N-Glycan biosynthesis_Homo sapiens_hsa005100.80892536
57beta-Alanine metabolism_Homo sapiens_hsa004100.74443285
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.73933664
59Sulfur relay system_Homo sapiens_hsa041220.72841479
60Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.71776627
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70535981
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67559105
63Prion diseases_Homo sapiens_hsa050200.67207593
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.64819024
65Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.62752663
66Small cell lung cancer_Homo sapiens_hsa052220.62174716
67Metabolic pathways_Homo sapiens_hsa011000.61529061
68Insulin signaling pathway_Homo sapiens_hsa049100.61055417
69Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.59732897
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.58750169
71Oocyte meiosis_Homo sapiens_hsa041140.57473854
72Pyruvate metabolism_Homo sapiens_hsa006200.57445258
73Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.57170599
74Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54814223
75Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54481341
76Endometrial cancer_Homo sapiens_hsa052130.54294428
77Fructose and mannose metabolism_Homo sapiens_hsa000510.53062327
78Pancreatic cancer_Homo sapiens_hsa052120.52461185
79Propanoate metabolism_Homo sapiens_hsa006400.52355884
80AMPK signaling pathway_Homo sapiens_hsa041520.52185648
81Non-small cell lung cancer_Homo sapiens_hsa052230.50978827
82Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49039197
83Viral carcinogenesis_Homo sapiens_hsa052030.47899220
84Phenylalanine metabolism_Homo sapiens_hsa003600.47062534
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47004879
86Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.46575085
87Other glycan degradation_Homo sapiens_hsa005110.45806248
88Linoleic acid metabolism_Homo sapiens_hsa005910.45535594
89Colorectal cancer_Homo sapiens_hsa052100.44990415
90Prostate cancer_Homo sapiens_hsa052150.44547005
91Fatty acid degradation_Homo sapiens_hsa000710.43730231
92Vibrio cholerae infection_Homo sapiens_hsa051100.43691136
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43654162
94Tryptophan metabolism_Homo sapiens_hsa003800.42743294
95Proteoglycans in cancer_Homo sapiens_hsa052050.42090065
96Lysine degradation_Homo sapiens_hsa003100.42021010
97Acute myeloid leukemia_Homo sapiens_hsa052210.41738396
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.40271059
99Glucagon signaling pathway_Homo sapiens_hsa049220.39473785
100Retinol metabolism_Homo sapiens_hsa008300.39125426
101Glioma_Homo sapiens_hsa052140.39107425
102Alzheimers disease_Homo sapiens_hsa050100.38662770
103Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37215049
104Tight junction_Homo sapiens_hsa045300.36710114
105Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.36368748
106Fatty acid elongation_Homo sapiens_hsa000620.36140732
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.35581621
108HIF-1 signaling pathway_Homo sapiens_hsa040660.35334395
109Arachidonic acid metabolism_Homo sapiens_hsa005900.35134096
110Peroxisome_Homo sapiens_hsa041460.34973018
111Wnt signaling pathway_Homo sapiens_hsa043100.32823784
112Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.32805838
113Herpes simplex infection_Homo sapiens_hsa051680.32518946
114Tyrosine metabolism_Homo sapiens_hsa003500.32140466
115Butanoate metabolism_Homo sapiens_hsa006500.30455255
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29888523
117Basal cell carcinoma_Homo sapiens_hsa052170.29461367
118Vitamin digestion and absorption_Homo sapiens_hsa049770.28791571
119Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.28635241
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.27900233
121Regulation of autophagy_Homo sapiens_hsa041400.26593089
122Galactose metabolism_Homo sapiens_hsa000520.25695183
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24505725
124HTLV-I infection_Homo sapiens_hsa051660.24155929
125Fat digestion and absorption_Homo sapiens_hsa049750.21610716
126Fatty acid metabolism_Homo sapiens_hsa012120.21057069
127Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.21005588
128Cardiac muscle contraction_Homo sapiens_hsa042600.20457895
129MicroRNAs in cancer_Homo sapiens_hsa052060.20419196
130Notch signaling pathway_Homo sapiens_hsa043300.19537588
131Hippo signaling pathway_Homo sapiens_hsa043900.18527406
132Steroid hormone biosynthesis_Homo sapiens_hsa001400.18449471
133Pentose and glucuronate interconversions_Homo sapiens_hsa000400.17999435
134Phototransduction_Homo sapiens_hsa047440.13464786
135Alcoholism_Homo sapiens_hsa050340.12463133

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