DNAJC18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.11478562
2presynaptic membrane assembly (GO:0097105)5.06787242
3neuron cell-cell adhesion (GO:0007158)4.85719485
4presynaptic membrane organization (GO:0097090)4.67134824
5behavioral response to nicotine (GO:0035095)4.59504568
6synaptic vesicle exocytosis (GO:0016079)4.56434219
7neuronal action potential propagation (GO:0019227)4.51176882
8vocalization behavior (GO:0071625)4.49887950
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.40136356
10regulation of short-term neuronal synaptic plasticity (GO:0048172)4.39342713
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.37917553
12postsynaptic membrane organization (GO:0001941)4.37247025
13regulation of synaptic vesicle exocytosis (GO:2000300)4.32663855
14protein localization to synapse (GO:0035418)4.22895674
15regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.18495159
16negative regulation of synaptic transmission, GABAergic (GO:0032229)4.15984786
17nucleobase catabolic process (GO:0046113)4.14173202
18neurotransmitter-gated ion channel clustering (GO:0072578)4.11557894
19synaptic vesicle maturation (GO:0016188)4.00292188
20regulation of glutamate receptor signaling pathway (GO:1900449)3.94568622
21glutamate secretion (GO:0014047)3.89558903
22synaptic vesicle docking involved in exocytosis (GO:0016081)3.80590123
23ionotropic glutamate receptor signaling pathway (GO:0035235)3.78852346
24membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.73704501
25regulation of synaptic vesicle transport (GO:1902803)3.72798948
26neuron-neuron synaptic transmission (GO:0007270)3.71043442
27synaptic transmission, glutamatergic (GO:0035249)3.68813683
28locomotory exploration behavior (GO:0035641)3.65751663
29glutamate receptor signaling pathway (GO:0007215)3.54895241
30startle response (GO:0001964)3.52568105
31gamma-aminobutyric acid transport (GO:0015812)3.51868663
32neurotransmitter secretion (GO:0007269)3.47771782
33nonmotile primary cilium assembly (GO:0035058)3.47457676
34negative regulation of neurotransmitter transport (GO:0051589)3.45389224
35gamma-aminobutyric acid signaling pathway (GO:0007214)3.40270951
36regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.38517065
37protein polyglutamylation (GO:0018095)3.31414732
38regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.29587599
39regulation of neuronal synaptic plasticity (GO:0048168)3.29542141
40central nervous system myelination (GO:0022010)3.29162269
41axon ensheathment in central nervous system (GO:0032291)3.29162269
42positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.28504370
43negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.28255179
44transmission of nerve impulse (GO:0019226)3.27942011
45negative regulation of neurotransmitter secretion (GO:0046929)3.25030215
46regulation of long-term neuronal synaptic plasticity (GO:0048169)3.22979002
47cerebellar granule cell differentiation (GO:0021707)3.22697477
48retinal ganglion cell axon guidance (GO:0031290)3.22659542
49regulation of excitatory postsynaptic membrane potential (GO:0060079)3.21897991
50long-term synaptic potentiation (GO:0060291)3.21659743
51positive regulation of membrane potential (GO:0045838)3.19288170
52positive regulation of synaptic transmission, GABAergic (GO:0032230)3.16862214
53regulation of synaptic transmission, GABAergic (GO:0032228)3.13523163
54neuron recognition (GO:0008038)3.13389204
55regulation of neurotransmitter secretion (GO:0046928)3.11469225
56regulation of synaptic transmission, glutamatergic (GO:0051966)3.10529549
57C4-dicarboxylate transport (GO:0015740)3.09181484
58regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.08332666
59negative regulation of dendrite morphogenesis (GO:0050774)3.07149701
60exploration behavior (GO:0035640)3.06363074
61G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06069200
62positive regulation of synapse assembly (GO:0051965)3.05756057
63regulation of postsynaptic membrane potential (GO:0060078)3.05129204
64establishment of mitochondrion localization (GO:0051654)3.04040117
65positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.03218473
66regulation of synapse structural plasticity (GO:0051823)3.02565136
67adult walking behavior (GO:0007628)3.01797289
68neurotransmitter transport (GO:0006836)3.01278082
69response to pheromone (GO:0019236)2.97466373
70positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.95591951
71regulation of respiratory system process (GO:0044065)2.95117136
72regulation of neurotransmitter transport (GO:0051588)2.95105618
73mechanosensory behavior (GO:0007638)2.95080717
74long-term memory (GO:0007616)2.94122922
75synapse assembly (GO:0007416)2.91586248
76neuromuscular synaptic transmission (GO:0007274)2.91463825
77regulation of voltage-gated calcium channel activity (GO:1901385)2.90558348
78striatum development (GO:0021756)2.88051196
79cerebral cortex radially oriented cell migration (GO:0021799)2.87662939
80neurotransmitter uptake (GO:0001504)2.86679136
81central nervous system projection neuron axonogenesis (GO:0021952)2.85669403
82dendrite development (GO:0016358)2.84676621
83membrane hyperpolarization (GO:0060081)2.84000193
84long-chain fatty acid biosynthetic process (GO:0042759)2.82757516
85L-amino acid import (GO:0043092)2.82593975
86membrane depolarization during action potential (GO:0086010)2.80170949
87limb bud formation (GO:0060174)2.78243202
88learning (GO:0007612)2.78111021
89positive regulation of neurotransmitter transport (GO:0051590)2.77990307
90membrane depolarization (GO:0051899)2.77821604
91regulation of synaptic plasticity (GO:0048167)2.77558021
92neuromuscular process controlling posture (GO:0050884)2.76890733
93auditory behavior (GO:0031223)2.76850762
94negative regulation of dendrite development (GO:2000171)2.76653650
95regulation of cilium movement (GO:0003352)2.75382089
96neuronal ion channel clustering (GO:0045161)2.73984108
97transferrin transport (GO:0033572)2.73805839
98cerebellar Purkinje cell differentiation (GO:0021702)2.71931045
99regulation of glutamate secretion (GO:0014048)2.69709757
100positive regulation of action potential (GO:0045760)2.69260037
101olfactory bulb development (GO:0021772)2.68608518
102dendritic spine morphogenesis (GO:0060997)2.68561170
103synaptic transmission (GO:0007268)2.67242497
104regulation of neurotransmitter levels (GO:0001505)2.67170445
105epithelial cilium movement (GO:0003351)2.66910504
106synaptic vesicle endocytosis (GO:0048488)2.66183898
107axonal fasciculation (GO:0007413)2.65813192
108membrane assembly (GO:0071709)2.65423132
109response to auditory stimulus (GO:0010996)2.65226089
110positive regulation of synaptic transmission (GO:0050806)2.64932205
111neuronal action potential (GO:0019228)2.64727972
112protein localization to cilium (GO:0061512)2.63517734
113regulation of female receptivity (GO:0045924)2.63507172
114response to histamine (GO:0034776)2.62729633
115behavioral response to cocaine (GO:0048148)2.62504747
116calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.62243049
117calcium ion-dependent exocytosis (GO:0017156)2.62149629
118amino acid import (GO:0043090)2.59891377
119epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.58589065
120cell migration in hindbrain (GO:0021535)2.57125965
121negative regulation of oligodendrocyte differentiation (GO:0048715)2.56036498
122retinal cone cell development (GO:0046549)2.54726228
123spinal cord development (GO:0021510)2.54449530
124central nervous system neuron axonogenesis (GO:0021955)2.49897713
125behavioral response to ethanol (GO:0048149)2.48406631
126synaptic transmission, cholinergic (GO:0007271)2.48182740
127somite development (GO:0061053)2.46734674
128regulation of microtubule-based movement (GO:0060632)2.46526833
129neurofilament cytoskeleton organization (GO:0060052)2.45550722
130establishment of protein localization to mitochondrial membrane (GO:0090151)2.44174952
131dendrite morphogenesis (GO:0048813)2.41275795
132glycosphingolipid biosynthetic process (GO:0006688)2.40966170
133negative regulation of cytosolic calcium ion concentration (GO:0051481)2.40889135
134head development (GO:0060322)2.40739735
135adult behavior (GO:0030534)2.39520001
136protein complex biogenesis (GO:0070271)2.39367251
137hippocampus development (GO:0021766)2.39067985
138synapse organization (GO:0050808)2.38354280
139intraciliary transport (GO:0042073)2.38300807
140cilium movement (GO:0003341)2.37679279
141inner ear receptor stereocilium organization (GO:0060122)2.37563936
142primary amino compound metabolic process (GO:1901160)2.36674621
143cilium morphogenesis (GO:0060271)2.36533978
144regulation of synapse assembly (GO:0051963)2.36262105
145serotonin metabolic process (GO:0042428)2.33555900
146behavioral fear response (GO:0001662)2.33455222
147behavioral defense response (GO:0002209)2.33455222
148detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.33174666
149neural tube formation (GO:0001841)2.33068273
150regulation of collateral sprouting (GO:0048670)2.32869132
151spinal cord motor neuron differentiation (GO:0021522)2.32819121
152cilium organization (GO:0044782)2.31951152
153NADH dehydrogenase complex assembly (GO:0010257)2.31665957

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.97138178
2GBX2_23144817_ChIP-Seq_PC3_Human4.27244061
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.85822839
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.72025597
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.70458444
6TAF15_26573619_Chip-Seq_HEK293_Human2.52045395
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.42012718
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.31832008
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.30676016
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.30676016
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.30450991
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.29954921
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.27323951
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.26727259
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.25860352
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.22508953
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.20519326
18ZFP57_27257070_Chip-Seq_ESCs_Mouse2.19030737
19MTF2_20144788_ChIP-Seq_MESCs_Mouse2.10731647
20* REST_21632747_ChIP-Seq_MESCs_Mouse2.10625999
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.10387533
22CTBP2_25329375_ChIP-Seq_LNCAP_Human2.06854256
23AR_21572438_ChIP-Seq_LNCaP_Human1.97519727
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.96910947
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.92338697
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.89680553
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.85296084
28EWS_26573619_Chip-Seq_HEK293_Human1.84063501
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.83931639
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.83756668
31P300_19829295_ChIP-Seq_ESCs_Human1.81936607
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.80601645
33SMAD4_21799915_ChIP-Seq_A2780_Human1.80516805
34DROSHA_22980978_ChIP-Seq_HELA_Human1.80505202
35SALL1_21062744_ChIP-ChIP_HESCs_Human1.78049478
36SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.77383551
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.70796387
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.69837140
39* REST_18959480_ChIP-ChIP_MESCs_Mouse1.69184639
40RARB_27405468_Chip-Seq_BRAIN_Mouse1.68676290
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.65760821
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.65640189
43BMI1_23680149_ChIP-Seq_NPCS_Mouse1.63907914
44HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.61877246
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.60228079
46PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.58962508
47RBPJ_22232070_ChIP-Seq_NCS_Mouse1.58591974
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.57105139
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.55869418
50RNF2_27304074_Chip-Seq_NSC_Mouse1.52342747
51IGF1R_20145208_ChIP-Seq_DFB_Human1.52218951
52FUS_26573619_Chip-Seq_HEK293_Human1.51618139
53ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.50280703
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.48224100
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.48217926
56ER_23166858_ChIP-Seq_MCF-7_Human1.47281382
57VDR_22108803_ChIP-Seq_LS180_Human1.46400188
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46366646
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45476744
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44855670
61MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44421738
62CBP_20019798_ChIP-Seq_JUKART_Human1.38270916
63IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38270916
64SMAD_19615063_ChIP-ChIP_OVARY_Human1.36067366
65IKZF1_21737484_ChIP-ChIP_HCT116_Human1.35344370
66AR_25329375_ChIP-Seq_VCAP_Human1.34865203
67STAT3_23295773_ChIP-Seq_U87_Human1.34637876
68POU5F1_16153702_ChIP-ChIP_HESCs_Human1.31238538
69AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.28071120
70TCF4_23295773_ChIP-Seq_U87_Human1.25575200
71SOX2_21211035_ChIP-Seq_LN229_Gbm1.22881541
72TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.21960063
73NANOG_18555785_Chip-Seq_ESCs_Mouse1.21173006
74CDX2_19796622_ChIP-Seq_MESCs_Mouse1.21093810
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20468050
76VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18946172
77BCAT_22108803_ChIP-Seq_LS180_Human1.17248148
78IRF1_19129219_ChIP-ChIP_H3396_Human1.17154765
79* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15384905
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14940726
81RUNX2_22187159_ChIP-Seq_PCA_Human1.13691768
82PRDM14_20953172_ChIP-Seq_ESCs_Human1.13595111
83PCGF2_27294783_Chip-Seq_NPCs_Mouse1.12862923
84MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.12489670
85ARNT_22903824_ChIP-Seq_MCF-7_Human1.11812086
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11804821
87PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11237109
88FLI1_27457419_Chip-Seq_LIVER_Mouse1.10820932
89E2F1_18555785_Chip-Seq_ESCs_Mouse1.10777771
90NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10166400
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09759873
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09759873
93P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09732527
94GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09577209
95EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.08658441
96CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08488746
97ZNF274_21170338_ChIP-Seq_K562_Hela1.08421289
98KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08301820
99* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06660704
100TP53_22573176_ChIP-Seq_HFKS_Human1.06515058
101P53_22387025_ChIP-Seq_ESCs_Mouse1.06154714
102MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05524488
103CMYC_18555785_Chip-Seq_ESCs_Mouse1.05441855
104TCF4_22108803_ChIP-Seq_LS180_Human1.05033349
105AHR_22903824_ChIP-Seq_MCF-7_Human1.04770154
106MYC_18940864_ChIP-ChIP_HL60_Human1.04167246
107SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03201949
108NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02411131
109SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02094554
110SOX9_26525672_Chip-Seq_HEART_Mouse1.01603318
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01552770
112ZNF217_24962896_ChIP-Seq_MCF-7_Human1.00698914
113JUN_21703547_ChIP-Seq_K562_Human0.99626127
114KDM2B_26808549_Chip-Seq_REH_Human0.99440826
115AR_19668381_ChIP-Seq_PC3_Human0.99415665
116FLI1_21867929_ChIP-Seq_TH2_Mouse0.97947267
117SMAD4_21741376_ChIP-Seq_EPCs_Human0.97355639
118* NANOG_19829295_ChIP-Seq_ESCs_Human0.96348850
119RING1B_27294783_Chip-Seq_ESCs_Mouse0.95871382
120* TAL1_26923725_Chip-Seq_HPCs_Mouse0.95104965
121P300_18555785_Chip-Seq_ESCs_Mouse0.94935655
122TP53_18474530_ChIP-ChIP_U2OS_Human0.94853536
123MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.94836572
124EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.93973487
125LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93850038

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.61377925
2MP0004859_abnormal_synaptic_plasticity4.24021923
3MP0004270_analgesia3.49323319
4MP0003635_abnormal_synaptic_transmissio3.32023311
5MP0009046_muscle_twitch3.27253359
6MP0009745_abnormal_behavioral_response2.99083357
7MP0002064_seizures2.93548678
8MP0002272_abnormal_nervous_system2.76740383
9MP0001968_abnormal_touch/_nociception2.76040316
10MP0002063_abnormal_learning/memory/cond2.66686820
11MP0001486_abnormal_startle_reflex2.54036416
12MP0002572_abnormal_emotion/affect_behav2.50810612
13MP0002734_abnormal_mechanical_nocicepti2.50139110
14MP0005646_abnormal_pituitary_gland2.49979505
15MP0002736_abnormal_nociception_after2.35641326
16MP0002735_abnormal_chemical_nociception2.29865648
17MP0005423_abnormal_somatic_nervous2.22348400
18MP0002102_abnormal_ear_morphology2.13496918
19MP0002067_abnormal_sensory_capabilities2.07778445
20MP0008877_abnormal_DNA_methylation1.99997441
21MP0001188_hyperpigmentation1.99329782
22MP0000778_abnormal_nervous_system1.92259950
23MP0009780_abnormal_chondrocyte_physiolo1.89294007
24MP0001984_abnormal_olfaction1.89128511
25MP0001529_abnormal_vocalization1.87389775
26MP0008569_lethality_at_weaning1.81336532
27MP0005551_abnormal_eye_electrophysiolog1.79733467
28MP0003787_abnormal_imprinting1.78631710
29MP0006276_abnormal_autonomic_nervous1.77965119
30MP0004142_abnormal_muscle_tone1.76720710
31MP0000569_abnormal_digit_pigmentation1.76130888
32MP0005171_absent_coat_pigmentation1.75608562
33MP0002653_abnormal_ependyma_morphology1.75224424
34MP0001970_abnormal_pain_threshold1.74871263
35MP0001440_abnormal_grooming_behavior1.72149048
36MP0001905_abnormal_dopamine_level1.70983116
37MP0002733_abnormal_thermal_nociception1.70420401
38MP0002184_abnormal_innervation1.67933434
39MP0004924_abnormal_behavior1.64602316
40MP0005386_behavior/neurological_phenoty1.64602316
41MP0004885_abnormal_endolymph1.64182622
42MP0002822_catalepsy1.62385403
43MP0003121_genomic_imprinting1.61877782
44MP0005645_abnormal_hypothalamus_physiol1.61250959
45MP0002557_abnormal_social/conspecific_i1.57556470
46MP0001986_abnormal_taste_sensitivity1.56542251
47MP0001501_abnormal_sleep_pattern1.55853038
48MP0003122_maternal_imprinting1.55127859
49MP0004133_heterotaxia1.53874697
50MP0000920_abnormal_myelination1.53397766
51MP0002882_abnormal_neuron_morphology1.49835939
52MP0005409_darkened_coat_color1.44055169
53MP0000955_abnormal_spinal_cord1.43006424
54MP0002938_white_spotting1.37155522
55MP0004742_abnormal_vestibular_system1.35522409
56MP0004811_abnormal_neuron_physiology1.33895590
57MP0002066_abnormal_motor_capabilities/c1.31458600
58MP0002229_neurodegeneration1.30729436
59MP0002234_abnormal_pharynx_morphology1.28788481
60MP0003879_abnormal_hair_cell1.28190309
61MP0002876_abnormal_thyroid_physiology1.24201421
62MP0000049_abnormal_middle_ear1.23874097
63MP0004145_abnormal_muscle_electrophysio1.22594276
64MP0004858_abnormal_nervous_system1.20207737
65MP0003011_delayed_dark_adaptation1.20197427
66MP0003634_abnormal_glial_cell1.19171373
67MP0000751_myopathy1.19068749
68MP0001502_abnormal_circadian_rhythm1.18976781
69MP0001963_abnormal_hearing_physiology1.17809514
70MP0000631_abnormal_neuroendocrine_gland1.15420744
71MP0002752_abnormal_somatic_nervous1.10254804
72MP0002837_dystrophic_cardiac_calcinosis1.09402742
73MP0001293_anophthalmia1.09307326
74MP0003633_abnormal_nervous_system1.09175658
75MP0003890_abnormal_embryonic-extraembry1.08847469
76MP0001485_abnormal_pinna_reflex1.06949935
77MP0003631_nervous_system_phenotype1.04843278
78MP0003136_yellow_coat_color1.03736174
79MP0005253_abnormal_eye_physiology1.03551011
80MP0003329_amyloid_beta_deposits1.01201404
81MP0003690_abnormal_glial_cell1.00402043
82MP0002152_abnormal_brain_morphology0.99295598
83MP0000566_synostosis0.98856631
84MP0006292_abnormal_olfactory_placode0.98531859
85MP0005410_abnormal_fertilization0.97145517
86MP0005499_abnormal_olfactory_system0.96474019
87MP0005394_taste/olfaction_phenotype0.96474019
88MP0003861_abnormal_nervous_system0.95651087
89MP0003119_abnormal_digestive_system0.95165581
90MP0008872_abnormal_physiological_respon0.91308116
91MP0003632_abnormal_nervous_system0.90885994
92MP0006072_abnormal_retinal_apoptosis0.90091645
93MP0000026_abnormal_inner_ear0.89654302
94MP0003937_abnormal_limbs/digits/tail_de0.88694292
95MP0001177_atelectasis0.87169940
96MP0004085_abnormal_heartbeat0.86914139
97MP0005391_vision/eye_phenotype0.86351184
98MP0005187_abnormal_penis_morphology0.85505033
99MP0002233_abnormal_nose_morphology0.85301884
100MP0005084_abnormal_gallbladder_morpholo0.84926347
101MP0002928_abnormal_bile_duct0.84588549
102MP0003698_abnormal_male_reproductive0.81829207
103MP0003283_abnormal_digestive_organ0.78227233
104MP0010386_abnormal_urinary_bladder0.76380114
105MP0003646_muscle_fatigue0.76339710
106MP0004043_abnormal_pH_regulation0.76320214
107MP0000015_abnormal_ear_pigmentation0.74308034
108MP0005195_abnormal_posterior_eye0.73691234
109MP0002090_abnormal_vision0.73369846
110MP0004215_abnormal_myocardial_fiber0.72933416
111MP0002638_abnormal_pupillary_reflex0.71923062
112MP0002069_abnormal_eating/drinking_beha0.71522680
113MP0001299_abnormal_eye_distance/0.71380861
114MP0002751_abnormal_autonomic_nervous0.71238037
115MP0002909_abnormal_adrenal_gland0.69494088
116MP0003938_abnormal_ear_development0.68608478
117MP0004134_abnormal_chest_morphology0.68363028
118MP0004147_increased_porphyrin_level0.66678865
119MP0003137_abnormal_impulse_conducting0.65753915
120MP0003183_abnormal_peptide_metabolism0.65396561
121MP0001943_abnormal_respiration0.65349827
122MP0000749_muscle_degeneration0.64576435
123MP0008789_abnormal_olfactory_epithelium0.64490336
124MP0005623_abnormal_meninges_morphology0.64358711

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.86834358
2Atonic seizures (HP:0010819)5.03878235
3Myokymia (HP:0002411)4.82137891
4Febrile seizures (HP:0002373)4.67255066
5Epileptic encephalopathy (HP:0200134)4.65850857
6Focal seizures (HP:0007359)4.27841500
7Hyperventilation (HP:0002883)3.75896771
8Pancreatic cysts (HP:0001737)3.42678215
9Pheochromocytoma (HP:0002666)3.41235645
10Progressive cerebellar ataxia (HP:0002073)3.41150307
11Absence seizures (HP:0002121)3.39079793
12Pancreatic fibrosis (HP:0100732)3.32282649
13Gait imbalance (HP:0002141)3.31545505
14Dialeptic seizures (HP:0011146)3.21540107
15Medial flaring of the eyebrow (HP:0010747)3.19184792
16Molar tooth sign on MRI (HP:0002419)3.17910579
17Abnormality of midbrain morphology (HP:0002418)3.17910579
18Nephronophthisis (HP:0000090)3.15355610
19Gaze-evoked nystagmus (HP:0000640)3.15058028
20Neuroendocrine neoplasm (HP:0100634)3.12030550
21Congenital primary aphakia (HP:0007707)3.06377676
22Broad-based gait (HP:0002136)3.03895254
23Nephrogenic diabetes insipidus (HP:0009806)2.93611292
24Action tremor (HP:0002345)2.87714245
25Generalized tonic-clonic seizures (HP:0002069)2.86294947
26Degeneration of the lateral corticospinal tracts (HP:0002314)2.84941118
27Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.84941118
28Visual hallucinations (HP:0002367)2.82284434
29Ankle clonus (HP:0011448)2.77962438
30Abnormal hair whorl (HP:0010721)2.73880349
31Scanning speech (HP:0002168)2.69045251
32Truncal ataxia (HP:0002078)2.65762627
33Type II lissencephaly (HP:0007260)2.65552734
34Absent/shortened dynein arms (HP:0200106)2.63632588
35Dynein arm defect of respiratory motile cilia (HP:0012255)2.63632588
36Progressive inability to walk (HP:0002505)2.62317418
37Abnormality of the renal medulla (HP:0100957)2.61621469
38Lissencephaly (HP:0001339)2.60464383
39Chronic hepatic failure (HP:0100626)2.59196471
40Abnormality of the corticospinal tract (HP:0002492)2.50513017
41Hypothermia (HP:0002045)2.49725806
42Optic nerve hypoplasia (HP:0000609)2.48870199
43Vaginal atresia (HP:0000148)2.48320183
44Genital tract atresia (HP:0001827)2.46911861
45Sensory axonal neuropathy (HP:0003390)2.44109154
46Limb dystonia (HP:0002451)2.41469280
47Intestinal atresia (HP:0011100)2.41138384
48Septo-optic dysplasia (HP:0100842)2.40693456
49Spastic gait (HP:0002064)2.39747053
50Dysdiadochokinesis (HP:0002075)2.38120351
51Fetal akinesia sequence (HP:0001989)2.37042179
52Specific learning disability (HP:0001328)2.35050527
53Dysmetria (HP:0001310)2.33447783
54Anxiety (HP:0000739)2.31888140
55Supranuclear gaze palsy (HP:0000605)2.30702370
56Retinal dysplasia (HP:0007973)2.29174887
57Narrow nasal bridge (HP:0000446)2.23681207
58Poor coordination (HP:0002370)2.23632828
59Pachygyria (HP:0001302)2.22515028
60Abnormal eating behavior (HP:0100738)2.21570550
61Cystic liver disease (HP:0006706)2.21284603
62Thickened helices (HP:0000391)2.21124503
63Acute necrotizing encephalopathy (HP:0006965)2.19508613
64Blue irides (HP:0000635)2.19445681
65Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.18850443
66Pendular nystagmus (HP:0012043)2.18567178
67Urinary bladder sphincter dysfunction (HP:0002839)2.18066319
68Absent speech (HP:0001344)2.17295483
69Impaired vibration sensation in the lower limbs (HP:0002166)2.17253623
70Lower limb muscle weakness (HP:0007340)2.13888406
71Depression (HP:0000716)2.12151061
72Progressive macrocephaly (HP:0004481)2.10400902
73Sclerocornea (HP:0000647)2.08588597
74Megalencephaly (HP:0001355)2.07326423
75Aplasia/Hypoplasia of the lens (HP:0008063)2.06199193
76Abnormal mitochondria in muscle tissue (HP:0008316)2.05715421
77Epileptiform EEG discharges (HP:0011182)2.05519992
78Failure to thrive in infancy (HP:0001531)2.05067620
79Excessive salivation (HP:0003781)2.03080361
80Drooling (HP:0002307)2.03080361
81Anencephaly (HP:0002323)2.02191057
82Akinesia (HP:0002304)2.00367219
83Acute encephalopathy (HP:0006846)2.00192782
84Postaxial hand polydactyly (HP:0001162)1.99600544
85Inability to walk (HP:0002540)1.98924573
86Aplasia/Hypoplasia of the tongue (HP:0010295)1.96432460
87Aplasia involving bones of the extremities (HP:0009825)1.96139403
88Aplasia involving bones of the upper limbs (HP:0009823)1.96139403
89Aplasia of the phalanges of the hand (HP:0009802)1.96139403
90Oligodactyly (hands) (HP:0001180)1.95356160
91Diplopia (HP:0000651)1.94072265
92Abnormality of binocular vision (HP:0011514)1.94072265
93Methylmalonic acidemia (HP:0002912)1.93791130
94Optic disc pallor (HP:0000543)1.93611026
95Hemiparesis (HP:0001269)1.93436662
96Amblyopia (HP:0000646)1.93019042
97Attenuation of retinal blood vessels (HP:0007843)1.92904120
98Bony spicule pigmentary retinopathy (HP:0007737)1.91265452
99Abnormality of the renal cortex (HP:0011035)1.90852136
100Dyschromatopsia (HP:0007641)1.89849840
101Central scotoma (HP:0000603)1.89828303
102Hyperglycinemia (HP:0002154)1.88973271
103Termporal pattern (HP:0011008)1.88569016
104Insidious onset (HP:0003587)1.88569016
105Congenital stationary night blindness (HP:0007642)1.87962277
106EEG with generalized epileptiform discharges (HP:0011198)1.87554669
107Colon cancer (HP:0003003)1.84571731
108Poor eye contact (HP:0000817)1.82291338
109Abnormal ciliary motility (HP:0012262)1.82145075
110Polyphagia (HP:0002591)1.81729630
111Aplasia/Hypoplasia of the tibia (HP:0005772)1.81601186
112Torticollis (HP:0000473)1.81182552
113Narrow forehead (HP:0000341)1.81115070
114Occipital encephalocele (HP:0002085)1.81045431
115Neoplasm of the peripheral nervous system (HP:0100007)1.80927656
116Anophthalmia (HP:0000528)1.80720509
117Generalized myoclonic seizures (HP:0002123)1.80475517
118Protruding tongue (HP:0010808)1.79976926
119Poor suck (HP:0002033)1.79843880
120Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.78610334
121Postaxial foot polydactyly (HP:0001830)1.78456127
122Esotropia (HP:0000565)1.77756351
123Hypsarrhythmia (HP:0002521)1.77655494
124Supernumerary spleens (HP:0009799)1.77326984
125Spastic tetraplegia (HP:0002510)1.77053996
126Gastrointestinal atresia (HP:0002589)1.76669151
127Growth hormone deficiency (HP:0000824)1.76466239
128Aplasia/Hypoplasia of the brainstem (HP:0007362)1.75658631
129Hypoplasia of the brainstem (HP:0002365)1.75658631
130True hermaphroditism (HP:0010459)1.73397606
131Cerebellar dysplasia (HP:0007033)1.72572092
132Urinary urgency (HP:0000012)1.69955607
133Alacrima (HP:0000522)1.69948967
134Decreased central vision (HP:0007663)1.69918540
135Postural instability (HP:0002172)1.69700145
136Mitochondrial inheritance (HP:0001427)1.68931177
137Abnormal respiratory motile cilium physiology (HP:0012261)1.68197884
138Abolished electroretinogram (ERG) (HP:0000550)1.67786231
139Abnormality of the labia minora (HP:0012880)1.67686614
140Increased CSF lactate (HP:0002490)1.67060690
141Genetic anticipation (HP:0003743)1.66553784
142Increased corneal curvature (HP:0100692)1.66413487
143Keratoconus (HP:0000563)1.66413487
144Morphological abnormality of the pyramidal tract (HP:0002062)1.64939203
145Short tibia (HP:0005736)1.64826383
146Broad foot (HP:0001769)1.64280257
147Tubular atrophy (HP:0000092)1.63912168
148Chorioretinal atrophy (HP:0000533)1.63594881
149Congenital hepatic fibrosis (HP:0002612)1.61752513

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.35018740
2PRPF4B3.56425020
3MAP2K73.20641742
4NTRK33.16342350
5MAP3K42.54251853
6TNIK2.53211864
7MAP4K22.45282226
8EPHA42.33987017
9MARK12.33148982
10FRK2.29251823
11MAP3K122.26121114
12OXSR12.21794194
13CDK192.20974569
14AKT32.15094800
15MAPK131.97133646
16SGK2231.89829509
17SGK4941.89829509
18STK391.79841508
19SGK21.76107365
20MINK11.75990730
21PLK21.67570211
22TRIM281.59094542
23ZAK1.56953110
24NTRK21.56936143
25MUSK1.53366483
26NUAK11.38656167
27DAPK21.38430326
28NEK61.34703966
29MAP2K41.29899773
30BCR1.26907068
31CDK51.18570419
32UHMK11.18341322
33CAMKK21.18069095
34PRKCG1.18015338
35BMPR21.17601797
36MAP3K91.13657968
37PAK61.10101115
38SGK31.09955496
39GRK51.07463543
40PKN11.06574155
41YES11.06490248
42CSNK1G11.06402782
43CAMK2A1.05909422
44CAMK2B1.05869405
45PLK41.02661158
46STK161.00685987
47NTRK10.99061533
48PHKG20.98613245
49PHKG10.98613245
50PRKCE0.97872372
51CSNK1A1L0.97740691
52WNK10.93834950
53DAPK10.91225971
54EPHB20.91068792
55DYRK30.90210077
56SRPK10.89189347
57SIK30.88554005
58VRK10.88013833
59PINK10.87816647
60SIK20.86807153
61PRKCH0.83927829
62CCNB10.83517129
63EPHA30.83331728
64MKNK10.83230968
65CAMK2D0.82682012
66PRKD30.82484858
67PLK30.82170354
68ARAF0.82059626
69TNK20.80033076
70STK38L0.79302647
71ROCK20.77043641
72ADRBK20.74451390
73FES0.73634524
74TIE10.72441828
75WNK40.70444619
76PDK30.70186972
77PDK40.70186972
78TAF10.68959858
79CDK180.68333294
80ERBB30.67834920
81CAMKK10.67724159
82BCKDK0.67021279
83BRAF0.65982056
84CSNK1G20.65404053
85CDK140.65097677
86CAMK2G0.63722120
87MAPK150.63374693
88CDK150.61822011
89BMPR1B0.61116277
90SGK10.60948808
91GRK70.60609815
92DYRK20.59973640
93DYRK1A0.59157159
94MYLK0.58574786
95MAPKAPK50.56953863
96CAMK10.56019051
97MKNK20.55533401
98PDK20.55033308
99INSRR0.54476208
100KSR10.54387048
101LIMK10.54277586
102PNCK0.52747914
103PTK2B0.51603037
104PRKCZ0.50876853
105PAK30.50132077
106OBSCN0.50035443
107CDK11A0.49573327
108CSNK1A10.48801734
109ADRBK10.46822760
110CSNK1G30.46763528
111GRK10.45856110
112VRK20.45786806
113ROCK10.45566424
114FGFR20.45343311
115NME10.44398140
116CAMK1G0.44054997
117CDK30.43730482
118PIK3CA0.43628585
119PRKG10.42599038
120WNK30.42373154
121PRKACA0.42184045
122TSSK60.42045701
123ERBB40.41586707
124CSNK1E0.41374375
125DYRK1B0.40724664
126IRAK20.40178186
127TLK10.40035740
128STK110.40013056
129FGR0.39147810
130CSNK1D0.38200341
131RIPK40.37921570
132MAPK120.37866971
133CAMK40.36895310
134TYRO30.35653861
135PLK10.35502195
136RPS6KA50.35368296
137PRKACB0.35158201

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.65348797
2Synaptic vesicle cycle_Homo sapiens_hsa047213.51038912
3GABAergic synapse_Homo sapiens_hsa047272.72566155
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.67332077
5Olfactory transduction_Homo sapiens_hsa047402.65778888
6Phototransduction_Homo sapiens_hsa047442.62973288
7Collecting duct acid secretion_Homo sapiens_hsa049662.56250097
8Morphine addiction_Homo sapiens_hsa050322.55145793
9Circadian entrainment_Homo sapiens_hsa047132.46377829
10Glutamatergic synapse_Homo sapiens_hsa047242.38661988
11Protein export_Homo sapiens_hsa030602.18912963
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.13090774
13Long-term potentiation_Homo sapiens_hsa047202.01940012
14Dopaminergic synapse_Homo sapiens_hsa047282.00724847
15Amphetamine addiction_Homo sapiens_hsa050311.96602063
16Serotonergic synapse_Homo sapiens_hsa047261.95874633
17Taste transduction_Homo sapiens_hsa047421.89695396
18Butanoate metabolism_Homo sapiens_hsa006501.82065521
19Vibrio cholerae infection_Homo sapiens_hsa051101.75924977
20Salivary secretion_Homo sapiens_hsa049701.73904920
21Cholinergic synapse_Homo sapiens_hsa047251.71432621
22Insulin secretion_Homo sapiens_hsa049111.69104777
23Oxidative phosphorylation_Homo sapiens_hsa001901.65508244
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65211644
25Long-term depression_Homo sapiens_hsa047301.62710090
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.56241365
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.48280915
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.47209035
29Propanoate metabolism_Homo sapiens_hsa006401.45599924
30Calcium signaling pathway_Homo sapiens_hsa040201.41040702
31Cocaine addiction_Homo sapiens_hsa050301.40614454
32Renin secretion_Homo sapiens_hsa049241.40168764
33Gastric acid secretion_Homo sapiens_hsa049711.40050211
34RNA polymerase_Homo sapiens_hsa030201.39021924
35Basal transcription factors_Homo sapiens_hsa030221.34901806
36Axon guidance_Homo sapiens_hsa043601.33533434
37Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.33330496
38SNARE interactions in vesicular transport_Homo sapiens_hsa041301.33003984
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.31137471
40Linoleic acid metabolism_Homo sapiens_hsa005911.27199272
41Aldosterone synthesis and secretion_Homo sapiens_hsa049251.25532520
42Oxytocin signaling pathway_Homo sapiens_hsa049211.22031212
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.20393216
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19160076
45Cardiac muscle contraction_Homo sapiens_hsa042601.17203508
46Nitrogen metabolism_Homo sapiens_hsa009101.17109431
47Parkinsons disease_Homo sapiens_hsa050121.16548848
48Alzheimers disease_Homo sapiens_hsa050101.15689774
49Fanconi anemia pathway_Homo sapiens_hsa034601.10277084
50cAMP signaling pathway_Homo sapiens_hsa040241.08646380
51Gap junction_Homo sapiens_hsa045401.07396349
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.06355823
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.04594231
54Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.02070141
55ErbB signaling pathway_Homo sapiens_hsa040120.98967814
56RNA degradation_Homo sapiens_hsa030180.97870003
57Rheumatoid arthritis_Homo sapiens_hsa053230.96688566
58Tryptophan metabolism_Homo sapiens_hsa003800.95169147
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.94666621
60Maturity onset diabetes of the young_Homo sapiens_hsa049500.94367255
61Selenocompound metabolism_Homo sapiens_hsa004500.93224383
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.93061585
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.90954625
64GnRH signaling pathway_Homo sapiens_hsa049120.90703814
65Fatty acid elongation_Homo sapiens_hsa000620.89640484
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89597885
67Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89177970
68Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.88656174
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.86641457
70cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81967508
71Melanogenesis_Homo sapiens_hsa049160.81307518
72Ether lipid metabolism_Homo sapiens_hsa005650.77381940
73Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.76814352
74Homologous recombination_Homo sapiens_hsa034400.75852361
75Huntingtons disease_Homo sapiens_hsa050160.74577078
76Basal cell carcinoma_Homo sapiens_hsa052170.74356083
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74354159
78Regulation of autophagy_Homo sapiens_hsa041400.73992817
79Dilated cardiomyopathy_Homo sapiens_hsa054140.72755386
80Phagosome_Homo sapiens_hsa041450.71335017
81Ras signaling pathway_Homo sapiens_hsa040140.70910456
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.70842754
83Peroxisome_Homo sapiens_hsa041460.69648597
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67072208
85Type II diabetes mellitus_Homo sapiens_hsa049300.67011934
86Caffeine metabolism_Homo sapiens_hsa002320.64975503
87MAPK signaling pathway_Homo sapiens_hsa040100.64734437
88Type I diabetes mellitus_Homo sapiens_hsa049400.64038237
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61337879
90Pancreatic secretion_Homo sapiens_hsa049720.60927637
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59365781
92Phospholipase D signaling pathway_Homo sapiens_hsa040720.58798939
93Estrogen signaling pathway_Homo sapiens_hsa049150.58380831
94Glioma_Homo sapiens_hsa052140.57670126
95Non-homologous end-joining_Homo sapiens_hsa034500.54028147
96Purine metabolism_Homo sapiens_hsa002300.53648663
97Hippo signaling pathway_Homo sapiens_hsa043900.53613724
98Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.52946805
99Alcoholism_Homo sapiens_hsa050340.52210945
100Sphingolipid metabolism_Homo sapiens_hsa006000.51522368
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.49464237
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48837435
103Fatty acid metabolism_Homo sapiens_hsa012120.48262034
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48237024
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.47800077
106Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46885345
107Arginine and proline metabolism_Homo sapiens_hsa003300.46647920
108Wnt signaling pathway_Homo sapiens_hsa043100.46543869
109Metabolic pathways_Homo sapiens_hsa011000.45953434
110Inositol phosphate metabolism_Homo sapiens_hsa005620.45752136
111Ovarian steroidogenesis_Homo sapiens_hsa049130.45699403
112beta-Alanine metabolism_Homo sapiens_hsa004100.45246451
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44913004
114Thyroid hormone synthesis_Homo sapiens_hsa049180.44083430
115Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.43233710
116Cysteine and methionine metabolism_Homo sapiens_hsa002700.42402962
117Circadian rhythm_Homo sapiens_hsa047100.41771906
118Renal cell carcinoma_Homo sapiens_hsa052110.41695737
119Endocytosis_Homo sapiens_hsa041440.41027072
120Primary bile acid biosynthesis_Homo sapiens_hsa001200.40628857
121Dorso-ventral axis formation_Homo sapiens_hsa043200.40363794
122Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.39702044
123Oocyte meiosis_Homo sapiens_hsa041140.39647424
124Choline metabolism in cancer_Homo sapiens_hsa052310.39576595
125Proteasome_Homo sapiens_hsa030500.39298358
126Melanoma_Homo sapiens_hsa052180.39067039
127Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.38344043
128Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37887736
129Rap1 signaling pathway_Homo sapiens_hsa040150.36643705
130RNA transport_Homo sapiens_hsa030130.35869228
131Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35320745
132Hedgehog signaling pathway_Homo sapiens_hsa043400.34899942
133Ribosome_Homo sapiens_hsa030100.31827013
134Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.31541812
135Steroid biosynthesis_Homo sapiens_hsa001000.31062749
136Neurotrophin signaling pathway_Homo sapiens_hsa047220.28620461
137Endometrial cancer_Homo sapiens_hsa052130.27779257
138Chemokine signaling pathway_Homo sapiens_hsa040620.26149362
139Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.25132992

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