DNAJC22

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.52736633
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.52736633
3L-phenylalanine metabolic process (GO:0006558)7.23403557
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.23403557
5aromatic amino acid family catabolic process (GO:0009074)6.78595963
6tryptophan catabolic process (GO:0006569)6.18582063
7indole-containing compound catabolic process (GO:0042436)6.18582063
8indolalkylamine catabolic process (GO:0046218)6.18582063
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.10100405
10kynurenine metabolic process (GO:0070189)6.04727390
11glyoxylate metabolic process (GO:0046487)5.87493952
12tryptophan metabolic process (GO:0006568)5.81244705
13bile acid biosynthetic process (GO:0006699)5.80032482
14cysteine metabolic process (GO:0006534)5.61027154
15urea cycle (GO:0000050)5.52424593
16urea metabolic process (GO:0019627)5.52424593
17epoxygenase P450 pathway (GO:0019373)5.43749518
18alpha-linolenic acid metabolic process (GO:0036109)5.41442864
19sulfur amino acid catabolic process (GO:0000098)5.37377390
20negative regulation of fibrinolysis (GO:0051918)5.33548941
21high-density lipoprotein particle remodeling (GO:0034375)5.30093674
22serine family amino acid catabolic process (GO:0009071)5.18221929
23complement activation, alternative pathway (GO:0006957)5.12726974
24regulation of protein activation cascade (GO:2000257)5.11983323
25regulation of fibrinolysis (GO:0051917)5.11924014
26peptidyl-glutamic acid carboxylation (GO:0017187)5.10793391
27protein carboxylation (GO:0018214)5.10793391
28nitrogen cycle metabolic process (GO:0071941)5.07906232
29bile acid metabolic process (GO:0008206)4.98483186
30aromatic amino acid family metabolic process (GO:0009072)4.96166471
31homocysteine metabolic process (GO:0050667)4.95948087
32fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.92308047
33lysine metabolic process (GO:0006553)4.87964003
34lysine catabolic process (GO:0006554)4.87964003
35regulation of complement activation (GO:0030449)4.78009709
36regulation of triglyceride catabolic process (GO:0010896)4.71877356
37omega-hydroxylase P450 pathway (GO:0097267)4.68068095
38amino-acid betaine metabolic process (GO:0006577)4.67121483
39reverse cholesterol transport (GO:0043691)4.67106447
40tyrosine metabolic process (GO:0006570)4.65804677
41regulation of cholesterol esterification (GO:0010872)4.64822033
42alpha-amino acid catabolic process (GO:1901606)4.63145059
43cellular ketone body metabolic process (GO:0046950)4.56835752
44plasma lipoprotein particle remodeling (GO:0034369)4.56225427
45protein-lipid complex remodeling (GO:0034368)4.56225427
46macromolecular complex remodeling (GO:0034367)4.56225427
47triglyceride homeostasis (GO:0070328)4.55666259
48acylglycerol homeostasis (GO:0055090)4.55666259
49drug catabolic process (GO:0042737)4.51962957
50negative regulation of sterol transport (GO:0032372)4.50642591
51negative regulation of cholesterol transport (GO:0032375)4.50642591
52glycine metabolic process (GO:0006544)4.46245030
53phospholipid efflux (GO:0033700)4.41024197
54bile acid and bile salt transport (GO:0015721)4.40651828
55cellular glucuronidation (GO:0052695)4.37319449
56indolalkylamine metabolic process (GO:0006586)4.36657613
57serine family amino acid metabolic process (GO:0009069)4.35175815
58glutamate metabolic process (GO:0006536)4.30212436
59cellular amino acid catabolic process (GO:0009063)4.29213646
60coenzyme catabolic process (GO:0009109)4.26793975
61cellular biogenic amine catabolic process (GO:0042402)4.26618202
62amine catabolic process (GO:0009310)4.26618202
63drug metabolic process (GO:0017144)4.25767047
64plasma lipoprotein particle clearance (GO:0034381)4.23022740
65cellular modified amino acid catabolic process (GO:0042219)4.21811871
66imidazole-containing compound metabolic process (GO:0052803)4.19253798
67serine family amino acid biosynthetic process (GO:0009070)4.17870754
68benzene-containing compound metabolic process (GO:0042537)4.14156852
69ethanol oxidation (GO:0006069)4.11179487
70cholesterol efflux (GO:0033344)4.05076435
71exogenous drug catabolic process (GO:0042738)4.03855452
72dicarboxylic acid biosynthetic process (GO:0043650)3.99400154
73ketone body metabolic process (GO:1902224)3.98459010
74aldehyde catabolic process (GO:0046185)3.97018443
75oxidative demethylation (GO:0070989)3.94393092
76uronic acid metabolic process (GO:0006063)3.91446449
77glucuronate metabolic process (GO:0019585)3.91446449
78arginine metabolic process (GO:0006525)3.89803470
79plasma lipoprotein particle assembly (GO:0034377)3.88581545
80phenylpropanoid metabolic process (GO:0009698)3.87288669
81regulation of cholesterol homeostasis (GO:2000188)3.85649338
82drug transmembrane transport (GO:0006855)3.83607303
83fibrinolysis (GO:0042730)3.83577521
84short-chain fatty acid metabolic process (GO:0046459)3.82227134
85regulation of bile acid biosynthetic process (GO:0070857)3.80710624
86urate metabolic process (GO:0046415)3.80289946
87carboxylic acid catabolic process (GO:0046395)3.75738495
88organic acid catabolic process (GO:0016054)3.75738495
89flavonoid metabolic process (GO:0009812)3.75586223
90low-density lipoprotein particle remodeling (GO:0034374)3.74977967
91positive regulation of lipoprotein lipase activity (GO:0051006)3.74906157
92positive regulation of triglyceride lipase activity (GO:0061365)3.74906157
93cholesterol homeostasis (GO:0042632)3.74418532
94phospholipid homeostasis (GO:0055091)3.72374771
95intestinal absorption (GO:0050892)3.72254306
96acetyl-CoA metabolic process (GO:0006084)3.71831828
97sterol homeostasis (GO:0055092)3.69310416
98cofactor catabolic process (GO:0051187)3.65455108
99very-low-density lipoprotein particle assembly (GO:0034379)3.64391320
100aspartate family amino acid catabolic process (GO:0009068)3.60971474
101positive regulation of lipid catabolic process (GO:0050996)3.60921303
102blood coagulation, intrinsic pathway (GO:0007597)3.60689202
103intestinal cholesterol absorption (GO:0030299)3.58605048
104complement activation, classical pathway (GO:0006958)3.57609574
105response to nitrosative stress (GO:0051409)3.56042090
106cytolysis (GO:0019835)3.55132425
107polyketide metabolic process (GO:0030638)3.45576955
108doxorubicin metabolic process (GO:0044598)3.45576955
109daunorubicin metabolic process (GO:0044597)3.45576955
110heme transport (GO:0015886)3.42974816
111negative regulation of lipase activity (GO:0060192)3.41503833
112regulation of plasminogen activation (GO:0010755)3.35345657
113S-adenosylmethionine metabolic process (GO:0046500)3.34852767
114plasma lipoprotein particle organization (GO:0071827)3.33623716
115water-soluble vitamin biosynthetic process (GO:0042364)3.30746587
116primary alcohol catabolic process (GO:0034310)3.29658969
117ethanol metabolic process (GO:0006067)3.28192062
118negative regulation of blood coagulation (GO:0030195)3.15167776
119negative regulation of hemostasis (GO:1900047)3.15167776
120xenobiotic catabolic process (GO:0042178)3.14478289
121aminoglycoside antibiotic metabolic process (GO:0030647)3.12008636
122negative regulation of coagulation (GO:0050819)3.11512012
123positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.09537973
124drug transport (GO:0015893)3.08459185
125alkaloid metabolic process (GO:0009820)3.07494006
126negative regulation of protein activation cascade (GO:2000258)2.99987144
127protein-lipid complex subunit organization (GO:0071825)2.92918410
128negative regulation of wound healing (GO:0061045)2.90895004
129quinone metabolic process (GO:1901661)2.90134897
1303-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.87284123
131purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.87284123
132vitamin biosynthetic process (GO:0009110)2.85575078
133protein-lipid complex assembly (GO:0065005)2.85562513
134xenobiotic metabolic process (GO:0006805)2.83545214
135cholesterol transport (GO:0030301)2.79550330
136sterol transport (GO:0015918)2.79550330

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.33518113
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse7.20385692
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.88450918
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.47507357
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.19106259
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse5.03775384
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.95438069
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.95095479
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.94854732
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.84176791
11ZNF274_21170338_ChIP-Seq_K562_Hela2.70341472
12VDR_22108803_ChIP-Seq_LS180_Human2.38478504
13HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.30286629
14ER_23166858_ChIP-Seq_MCF-7_Human2.19771017
15TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.03965265
16TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.01643833
17ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.8658395
18ZNF217_24962896_ChIP-Seq_MCF-7_Human1.82627003
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.68747430
20PIAS1_25552417_ChIP-Seq_VCAP_Human1.67341377
21IGF1R_20145208_ChIP-Seq_DFB_Human1.64642467
22FOXA2_19822575_ChIP-Seq_HepG2_Human1.63182298
23CLOCK_20551151_ChIP-Seq_293T_Human1.61272822
24GBX2_23144817_ChIP-Seq_PC3_Human1.58494759
25AHR_22903824_ChIP-Seq_MCF-7_Human1.54244790
26HTT_18923047_ChIP-ChIP_STHdh_Human1.51237251
27ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.49750872
28* HNF4A_19822575_ChIP-Seq_HepG2_Human1.48255785
29FOXM1_26456572_ChIP-Seq_MCF-7_Human1.46139263
30AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.45959525
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.45691154
32STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.35104958
33FLI1_27457419_Chip-Seq_LIVER_Mouse1.33433291
34ARNT_22903824_ChIP-Seq_MCF-7_Human1.31480748
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.31451487
36FOXA1_25329375_ChIP-Seq_VCAP_Human1.31013816
37FOXA1_27270436_Chip-Seq_PROSTATE_Human1.31013816
38PCGF2_27294783_Chip-Seq_ESCs_Mouse1.26676998
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.25401104
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24765419
41EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.24579654
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23401815
43SOX2_27498859_Chip-Seq_STOMACH_Mouse1.22486380
44GATA1_22025678_ChIP-Seq_K562_Human1.22331984
45FUS_26573619_Chip-Seq_HEK293_Human1.21489367
46SALL1_21062744_ChIP-ChIP_HESCs_Human1.19142138
47HIF1A_21447827_ChIP-Seq_MCF-7_Human1.18831705
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18248818
49EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.18140565
50TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.17348713
51* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.16593826
52TCF4_22108803_ChIP-Seq_LS180_Human1.16262610
53FOXA1_21572438_ChIP-Seq_LNCaP_Human1.16174453
54P300_19829295_ChIP-Seq_ESCs_Human1.13769571
55IRF1_19129219_ChIP-ChIP_H3396_Human1.13279243
56IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.13114357
57CBP_20019798_ChIP-Seq_JUKART_Human1.13114357
58NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12793295
59HOXB7_26014856_ChIP-Seq_BT474_Human1.10142755
60HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09485288
61ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.09070066
62GATA4_25053715_ChIP-Seq_YYC3_Human1.08880235
63ESR1_15608294_ChIP-ChIP_MCF-7_Human1.08450283
64NFE2_27457419_Chip-Seq_LIVER_Mouse1.07316969
65THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.06968933
66CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.06838860
67KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06802511
68AR_25329375_ChIP-Seq_VCAP_Human1.06532193
69STAT3_23295773_ChIP-Seq_U87_Human1.05927229
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05187047
71SOX2_19829295_ChIP-Seq_ESCs_Human1.04785279
72NANOG_19829295_ChIP-Seq_ESCs_Human1.04785279
73EWS_26573619_Chip-Seq_HEK293_Human1.02379385
74TCF4_18268006_ChIP-ChIP_LS174T_Human1.00473389
75GATA3_21878914_ChIP-Seq_MCF-7_Human1.00195322
76NCOR_22424771_ChIP-Seq_293T_Human0.99633992
77SUZ12_27294783_Chip-Seq_NPCs_Mouse0.99578940
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98107587
79CJUN_26792858_Chip-Seq_BT549_Human0.97983425
80TAF15_26573619_Chip-Seq_HEK293_Human0.97577109
81RARG_19884340_ChIP-ChIP_MEFs_Mouse0.96703512
82GABP_17652178_ChIP-ChIP_JURKAT_Human0.96530449
83ERA_21632823_ChIP-Seq_H3396_Human0.95513440
84* TP53_22573176_ChIP-Seq_HFKS_Human0.95140206
85CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94608727
86ETV2_25802403_ChIP-Seq_MESCs_Mouse0.94042579
87SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94022350
88TCF4_23295773_ChIP-Seq_U87_Human0.93601554
89PADI4_21655091_ChIP-ChIP_MCF-7_Human0.93565731
90IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.93305723
91KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.92136093
92ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.91786424
93EZH2_27294783_Chip-Seq_NPCs_Mouse0.91579786
94PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91555913
95ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.88304858
96CDX2_20551321_ChIP-Seq_CACO-2_Human0.84860656
97NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.83447955
98SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.82962347
99ESR2_21235772_ChIP-Seq_MCF-7_Human0.81993856
100ZNF263_19887448_ChIP-Seq_K562_Human0.81670589
101PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.80774905
102KAP1_22055183_ChIP-Seq_ESCs_Mouse0.80068974
103SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.79293588
104IRF8_22096565_ChIP-ChIP_GC-B_Human0.78315430
105AUTS2_25519132_ChIP-Seq_293T-REX_Human0.76717408
106CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.74937580
107STAT3_1855785_ChIP-Seq_MESCs_Mouse0.74728838
108RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.74447679
109* RARA_24833708_ChIP-Seq_LIVER_Mouse0.73962603
110AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.73429164
111SALL4_18804426_ChIP-ChIP_XEN_Mouse0.73373309
112FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.73063468
113BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.71252674
114Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.70968041
115BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.70633165
116GATA6_25053715_ChIP-Seq_YYC3_Human0.66059726
117ESR1_21235772_ChIP-Seq_MCF-7_Human0.64002756
118RAD21_21589869_ChIP-Seq_MESCs_Mouse0.62883798
119NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.61919424
120EGR1_19032775_ChIP-ChIP_M12_Human0.61437452
121* RARB_24833708_ChIP-Seq_LIVER_Mouse0.60127744
122LXR_22292898_ChIP-Seq_THP-1_Human0.59958851
123CEBPB_22108803_ChIP-Seq_LS180_Human0.59084158
124NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.58114170
125NRF2_20460467_ChIP-Seq_MEFs_Mouse0.58114170
126PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.57062870
127FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.56724754
128FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.54418123
129FOXO3_23340844_ChIP-Seq_DLD1_Human0.53637603
130MYC_19915707_ChIP-ChIP_AK7_Human0.53558344
131AR_20517297_ChIP-Seq_VCAP_Human0.52806731
132FOXA1_25552417_ChIP-Seq_VCAP_Human0.52254054
133* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.51192056
134PPAR_26484153_Chip-Seq_NCI-H1993_Human0.50765644
135ESET_19884257_ChIP-Seq_ESCs_Mouse0.50614199
136SOX2_20726797_ChIP-Seq_SW620_Human0.47775101
137P53_21459846_ChIP-Seq_SAOS-2_Human0.47061293
138* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.46881230
139CBP_21632823_ChIP-Seq_H3396_Human0.45569354
140PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.45191258
141STAT1_17558387_ChIP-Seq_HELA_Human0.44022774
142* TAF2_19829295_ChIP-Seq_ESCs_Human0.43809092
143ESR1_20079471_ChIP-ChIP_T-47D_Human0.43560966
144PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.42418821
145POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.42406727
146GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.41589071
147E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.41014467
148GATA2_19941826_ChIP-Seq_K562_Human0.40823810
149ERG_21242973_ChIP-ChIP_JURKAT_Human0.39895404
150RACK7_27058665_Chip-Seq_MCF-7_Human0.39733409
151* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.39244010
152CDX2_22108803_ChIP-Seq_LS180_Human0.39153187
153GATA3_24758297_ChIP-Seq_MCF-7_Human0.38739321
154SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.37958352
155STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.37730473
156ERG_20517297_ChIP-Seq_VCAP_Human0.37166438
157ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.36864312
158GATA1_19941826_ChIP-Seq_K562_Human0.36725234
159BCOR_27268052_Chip-Seq_Bcells_Human0.36652226
160FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.35743494
161SOX3_22085726_ChIP-Seq_MUSCLE_Mouse0.35741229
162BCAT_22108803_ChIP-Seq_LS180_Human0.35320102
163* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.35115103

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.19857364
2MP0005360_urolithiasis7.89298932
3MP0005085_abnormal_gallbladder_physiolo6.36220803
4MP0005365_abnormal_bile_salt6.04660037
5MP0008875_abnormal_xenobiotic_pharmacok5.00622395
6MP0003806_abnormal_nucleotide_metabolis4.35272541
7MP0003252_abnormal_bile_duct3.93936942
8MP0010329_abnormal_lipoprotein_level3.48461153
9MP0009840_abnormal_foam_cell3.15764177
10MP0005083_abnormal_biliary_tract3.01414178
11MP0005332_abnormal_amino_acid2.91683424
12MP0003195_calcinosis2.79678349
13MP0001666_abnormal_nutrient_absorption2.77942365
14MP0009780_abnormal_chondrocyte_physiolo2.40772881
15MP0004019_abnormal_vitamin_homeostasis2.38597965
16MP0003191_abnormal_cellular_cholesterol2.23030010
17MP0002138_abnormal_hepatobiliary_system2.12114994
18MP0000609_abnormal_liver_physiology2.09804988
19MP0002118_abnormal_lipid_homeostasis2.03460192
20MP0003868_abnormal_feces_composition1.92325799
21MP0005319_abnormal_enzyme/_coenzyme1.83127149
22MP0001764_abnormal_homeostasis1.61413006
23MP0005451_abnormal_body_composition1.56471116
24MP0005584_abnormal_enzyme/coenzyme_acti1.55149834
25MP0009643_abnormal_urine_homeostasis1.44357131
26MP0009697_abnormal_copulation1.44339246
27MP0002909_abnormal_adrenal_gland1.43067782
28MP0003011_delayed_dark_adaptation1.34729300
29MP0000427_abnormal_hair_cycle1.32307781
30MP0003186_abnormal_redox_activity1.31217052
31MP0010386_abnormal_urinary_bladder1.24424584
32MP0005551_abnormal_eye_electrophysiolog1.23604717
33MP0003705_abnormal_hypodermis_morpholog1.20211957
34MP0010678_abnormal_skin_adnexa1.19894561
35MP0005646_abnormal_pituitary_gland1.16999002
36MP0000383_abnormal_hair_follicle1.15708376
37MP0000598_abnormal_liver_morphology1.15179483
38MP0003656_abnormal_erythrocyte_physiolo1.10531033
39MP0000566_synostosis1.10195928
40MP0001873_stomach_inflammation1.09617495
41MP0005636_abnormal_mineral_homeostasis1.09238938
42MP0005647_abnormal_sex_gland1.01685215
43MP0003183_abnormal_peptide_metabolism0.98538358
44MP0009764_decreased_sensitivity_to0.98203122
45MP0002160_abnormal_reproductive_system0.98196238
46MP0002254_reproductive_system_inflammat0.97345122
47MP0000604_amyloidosis0.97308485
48MP0005379_endocrine/exocrine_gland_phen0.95582670
49MP0009763_increased_sensitivity_to0.95008970
50MP0005408_hypopigmentation0.93723815
51MP0005084_abnormal_gallbladder_morpholo0.92422317
52MP0003943_abnormal_hepatobiliary_system0.92299399
53MP0004147_increased_porphyrin_level0.90222047
54MP0001944_abnormal_pancreas_morphology0.89844132
55MP0002938_white_spotting0.88772026
56MP0009642_abnormal_blood_homeostasis0.85446586
57MP0005670_abnormal_white_adipose0.84681154
58MP0008469_abnormal_protein_level0.84666917
59MP0003122_maternal_imprinting0.82536672
60MP0006036_abnormal_mitochondrial_physio0.81072320
61MP0002098_abnormal_vibrissa_morphology0.80035208
62MP0005376_homeostasis/metabolism_phenot0.78204197
63MP0005220_abnormal_exocrine_pancreas0.77141349
64MP0010368_abnormal_lymphatic_system0.77070215
65MP0009765_abnormal_xenobiotic_induced0.76240781
66MP0001756_abnormal_urination0.75196463
67MP0003950_abnormal_plasma_membrane0.74785762
68MP0002876_abnormal_thyroid_physiology0.74001352
69MP0001529_abnormal_vocalization0.73951612
70MP0002078_abnormal_glucose_homeostasis0.73359348
71MP0001664_abnormal_digestion0.73165717
72MP0003283_abnormal_digestive_organ0.72746366
73MP0004133_heterotaxia0.71221878
74MP0005389_reproductive_system_phenotype0.69873617
75MP0001324_abnormal_eye_pigmentation0.69400958
76MP0001919_abnormal_reproductive_system0.67488761
77MP0009053_abnormal_anal_canal0.67470104
78MP0001661_extended_life_span0.66981547
79MP0002971_abnormal_brown_adipose0.66178904
80MP0005266_abnormal_metabolism0.64978413
81MP0005187_abnormal_penis_morphology0.63645012
82MP0005334_abnormal_fat_pad0.63210605
83MP0000647_abnormal_sebaceous_gland0.63151828
84MP0002136_abnormal_kidney_physiology0.62784484
85MP0002282_abnormal_trachea_morphology0.61299596
86MP0005535_abnormal_body_temperature0.61138422
87MP0003890_abnormal_embryonic-extraembry0.59583857
88MP0004130_abnormal_muscle_cell0.58491631
89MP0001485_abnormal_pinna_reflex0.58453121
90MP0005645_abnormal_hypothalamus_physiol0.58084167
91MP0003936_abnormal_reproductive_system0.57786694
92MP0002693_abnormal_pancreas_physiology0.57673697
93MP0003329_amyloid_beta_deposits0.56375411
94MP0006035_abnormal_mitochondrial_morpho0.54139421
95MP0004264_abnormal_extraembryonic_tissu0.53718804
96MP0005448_abnormal_energy_balance0.53393916
97MP0002102_abnormal_ear_morphology0.53388485
98MP0003718_maternal_effect0.53093875
99MP0000462_abnormal_digestive_system0.51860486
100MP0005395_other_phenotype0.51460475
101MP0003123_paternal_imprinting0.51333151
102MP0002751_abnormal_autonomic_nervous0.51281256
103MP0005410_abnormal_fertilization0.51224931
104MP0001881_abnormal_mammary_gland0.51195881
105MP0004043_abnormal_pH_regulation0.50865500
106MP0002928_abnormal_bile_duct0.50706065
107MP0003690_abnormal_glial_cell0.50308729
108MP0005253_abnormal_eye_physiology0.49754472
109MP0000639_abnormal_adrenal_gland0.48201989
110MP0005666_abnormal_adipose_tissue0.47891550
111MP0003638_abnormal_response/metabolism_0.47638351
112MP0002089_abnormal_postnatal_growth/wei0.47178925
113MP0005195_abnormal_posterior_eye0.46202077
114MP0010234_abnormal_vibrissa_follicle0.45703109
115MP0002822_catalepsy0.44445738
116MP0008873_increased_physiological_sensi0.44112917
117MP0003937_abnormal_limbs/digits/tail_de0.43911597
118MP0003724_increased_susceptibility_to0.43519807
119MP0008872_abnormal_physiological_respon0.43338483
120MP0002796_impaired_skin_barrier0.43196336
121MP0005464_abnormal_platelet_physiology0.43089369
122MP0001986_abnormal_taste_sensitivity0.42778159
123MP0000470_abnormal_stomach_morphology0.42469459
124MP0003953_abnormal_hormone_level0.40907013
125MP0005166_decreased_susceptibility_to0.40245069
126MP0001765_abnormal_ion_homeostasis0.39711029
127MP0004782_abnormal_surfactant_physiolog0.38707185
128MP0008874_decreased_physiological_sensi0.37517346
129MP0009384_cardiac_valve_regurgitation0.37079790
130MP0009672_abnormal_birth_weight0.36499225
131MP0000579_abnormal_nail_morphology0.33626038
132MP0000230_abnormal_systemic_arterial0.33512652
133MP0003436_decreased_susceptibility_to0.33292627
134MP0003075_altered_response_to0.33096747
135MP0005248_abnormal_Harderian_gland0.32499745
136MP0002168_other_aberrant_phenotype0.32113425
137MP0009115_abnormal_fat_cell0.30988036
138MP0005058_abnormal_lysosome_morphology0.30461340
139MP0000538_abnormal_urinary_bladder0.29700053
140MP0003300_gastrointestinal_ulcer0.28872589
141MP0000249_abnormal_blood_vessel0.28544052
142MP0003453_abnormal_keratinocyte_physiol0.28485765
143MP0002970_abnormal_white_adipose0.28249556
144MP0002060_abnormal_skin_morphology0.27833295
145MP0001845_abnormal_inflammatory_respons0.27674226
146MP0005167_abnormal_blood-brain_barrier0.27395378
147MP0004883_abnormal_blood_vessel0.27185896

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)7.20354504
2Abnormality of aromatic amino acid family metabolism (HP:0004338)7.19361105
3Deep venous thrombosis (HP:0002625)7.01401912
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.47340114
5Hypobetalipoproteinemia (HP:0003563)6.23261784
6Xanthomatosis (HP:0000991)6.14632145
7Prolonged partial thromboplastin time (HP:0003645)6.09813681
8Hyperlipoproteinemia (HP:0010980)5.08297514
9Complement deficiency (HP:0004431)5.08074060
10Hypolipoproteinemia (HP:0010981)4.71823789
11Hyperammonemia (HP:0001987)4.61617824
12Abnormality of glutamine family amino acid metabolism (HP:0010902)4.57795307
13Joint hemorrhage (HP:0005261)4.46340787
14Hyperglycinemia (HP:0002154)4.46172687
15Epidermoid cyst (HP:0200040)4.35023991
16Abnormality of sulfur amino acid metabolism (HP:0004339)4.29470293
17Ketosis (HP:0001946)4.28717286
18Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.25737172
19Abnormality of aspartate family amino acid metabolism (HP:0010899)4.25686671
20Abnormality of the common coagulation pathway (HP:0010990)4.20453501
21Hyperglycinuria (HP:0003108)4.19605403
22Fat malabsorption (HP:0002630)4.16061402
23Hypoalphalipoproteinemia (HP:0003233)4.11961663
24Abnormality of glycine metabolism (HP:0010895)4.10111738
25Abnormality of serine family amino acid metabolism (HP:0010894)4.10111738
26Abnormality of methionine metabolism (HP:0010901)4.05969516
27Hypoglycemic coma (HP:0001325)3.95751983
28Abnormality of pyrimidine metabolism (HP:0004353)3.78517314
29Abnormality of complement system (HP:0005339)3.74918070
30Conjugated hyperbilirubinemia (HP:0002908)3.74290814
31Abnormality of the intrinsic pathway (HP:0010989)3.55969295
32Hypercholesterolemia (HP:0003124)3.44053456
33Abnormality of fatty-acid metabolism (HP:0004359)3.40866770
34Abnormality of nucleobase metabolism (HP:0010932)3.29213996
35Hyperbilirubinemia (HP:0002904)3.27272470
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.26244647
37Ketoacidosis (HP:0001993)3.18697763
38Delayed CNS myelination (HP:0002188)3.12520888
39Steatorrhea (HP:0002570)3.05532618
40Abnormality of purine metabolism (HP:0004352)3.04562337
41Abnormality of serum amino acid levels (HP:0003112)3.03099083
42Hepatocellular carcinoma (HP:0001402)2.97137403
43Gout (HP:0001997)2.97022843
44Metabolic acidosis (HP:0001942)2.89711324
45Spontaneous abortion (HP:0005268)2.83754077
46Abnormality of the renal cortex (HP:0011035)2.80658146
47Myocardial infarction (HP:0001658)2.79281148
48Lethargy (HP:0001254)2.74697799
49Vascular calcification (HP:0004934)2.71805366
50Dicarboxylic aciduria (HP:0003215)2.70531255
51Abnormality of dicarboxylic acid metabolism (HP:0010995)2.70531255
52Hypochromic microcytic anemia (HP:0004840)2.69150811
53Skin nodule (HP:0200036)2.65345631
54Acanthocytosis (HP:0001927)2.59657852
55Pancreatic cysts (HP:0001737)2.58393309
56Potter facies (HP:0002009)2.56059890
57Facial shape deformation (HP:0011334)2.56059890
58Systemic lupus erythematosus (HP:0002725)2.56013216
59Spastic diplegia (HP:0001264)2.51773080
60Hypoglycemic seizures (HP:0002173)2.50866739
61Malnutrition (HP:0004395)2.50755534
62Abnormal gallbladder physiology (HP:0012438)2.50461099
63Cholecystitis (HP:0001082)2.50461099
64Cerebral edema (HP:0002181)2.50000648
65Hypothermia (HP:0002045)2.48825248
66Pigmentary retinal degeneration (HP:0001146)2.44853311
67Abnormal gallbladder morphology (HP:0012437)2.42207556
68Cardiovascular calcification (HP:0011915)2.40068326
69Cholelithiasis (HP:0001081)2.37201654
70Irritability (HP:0000737)2.36733387
71Fair hair (HP:0002286)2.34047588
72Neonatal onset (HP:0003623)2.33237060
73Generalized aminoaciduria (HP:0002909)2.28879277
74Esophageal varix (HP:0002040)2.25752232
75Hyperphosphaturia (HP:0003109)2.24932771
76Late onset (HP:0003584)2.24367210
77Glomerulonephritis (HP:0000099)2.24083773
78Proximal tubulopathy (HP:0000114)2.22449766
79Alkalosis (HP:0001948)2.21148998
80Hyperuricemia (HP:0002149)2.19394848
81Increased purine levels (HP:0004368)2.19394848
82Vomiting (HP:0002013)2.18090979
83J-shaped sella turcica (HP:0002680)2.17873392
84Mitral stenosis (HP:0001718)2.16032272
85Abnormality of proline metabolism (HP:0010907)2.15880762
86Hydroxyprolinuria (HP:0003080)2.15880762
87Sensorimotor neuropathy (HP:0007141)2.15093699
88Pancreatitis (HP:0001733)2.14970535
89Rickets (HP:0002748)2.14783410
90Enlarged kidneys (HP:0000105)2.14315139
91Type II lissencephaly (HP:0007260)2.13885440
92Recurrent gram-negative bacterial infections (HP:0005420)2.13157449
93Abnormality of alanine metabolism (HP:0010916)2.10376999
94Hyperalaninemia (HP:0003348)2.10376999
95Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.10376999
96Gingival bleeding (HP:0000225)2.08859995
97Amyloidosis (HP:0011034)2.05765818
98Bile duct proliferation (HP:0001408)2.05585515
99Abnormal biliary tract physiology (HP:0012439)2.05585515
100Brushfield spots (HP:0001088)2.05408683
101Glycosuria (HP:0003076)2.05270734
102Abnormality of urine glucose concentration (HP:0011016)2.05270734
103Hyperinsulinemic hypoglycemia (HP:0000825)2.03168131
104Concave nail (HP:0001598)2.01579956
105Abnormal cartilage morphology (HP:0002763)2.01433855
106Opisthotonus (HP:0002179)2.00552687
107Tubular atrophy (HP:0000092)1.99570144
108Abnormality of the gallbladder (HP:0005264)1.99102302
109Chorioretinal atrophy (HP:0000533)1.98892192
110Menorrhagia (HP:0000132)1.98491733
111Thrombophlebitis (HP:0004418)1.97371322
112Abnormality of the nasal septum (HP:0000419)1.97329779
113Hypophosphatemic rickets (HP:0004912)1.95272552
114Poikilocytosis (HP:0004447)1.95268565
115Abnormal enzyme/coenzyme activity (HP:0012379)1.94724408
116Arthropathy (HP:0003040)1.92346041
117Hemorrhage of the eye (HP:0011885)1.91156219
118Azoospermia (HP:0000027)1.90119032
119Abnormal urine phosphate concentration (HP:0012599)1.89281433
120Abnormality of vitamin metabolism (HP:0100508)1.87016520
121Large for gestational age (HP:0001520)1.86912923
122Abnormality of the vitreous humor (HP:0004327)1.83859473
123Megaloblastic anemia (HP:0001889)1.83497302
124Amelogenesis imperfecta (HP:0000705)1.82995208
125Pendular nystagmus (HP:0012043)1.82924275
126Abnormality of transition element cation homeostasis (HP:0011030)1.81391092
127Generalized hypopigmentation of hair (HP:0011358)1.81386952
128True hermaphroditism (HP:0010459)1.79197502
129Cystic liver disease (HP:0006706)1.78733706
130Renal cortical cysts (HP:0000803)1.77689785
131Pancreatic fibrosis (HP:0100732)1.76243036
132Cerebellar dysplasia (HP:0007033)1.75809683
133Abnormality of vitamin B metabolism (HP:0004340)1.72719527
134Nephritis (HP:0000123)1.72266074
135Congenital stationary night blindness (HP:0007642)1.71320836
136Molar tooth sign on MRI (HP:0002419)1.70804247
137Abnormality of midbrain morphology (HP:0002418)1.70804247
138Hyperventilation (HP:0002883)1.70195583
139Reduced antithrombin III activity (HP:0001976)1.69844610

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.03042731
2FGFR44.36751511
3ERN14.13889017
4SIK14.07199523
5ERBB43.36854822
6STK393.20172888
7TAOK32.88387359
8MST1R2.83779265
9INSRR2.67402521
10PKN22.57778365
11MAP3K122.28129776
12BMPR1B2.26965076
13MAPK112.01224058
14MST42.01173218
15MAPKAPK31.97262726
16MUSK1.95905595
17STK38L1.95093177
18MAP2K41.94400250
19FLT31.87642586
20MAP4K21.84819115
21FRK1.84167006
22TRIB31.83623791
23ADRBK21.83338242
24LATS11.83095355
25CASK1.80054295
26PIK3CG1.69495521
27PTK61.67382277
28LMTK21.57311624
29EIF2AK11.55153182
30TRIM281.54940140
31ZAK1.50821612
32TYK21.49138541
33ABL21.42456524
34EIF2AK31.40738242
35TNIK1.37397670
36BRSK21.35695126
37GRK61.32075498
38NEK91.31583690
39DAPK21.26066436
40FER1.23188799
41MAP3K71.22863059
42KDR1.22468932
43ERBB21.20835470
44MAP3K31.14923421
45MET1.12475746
46PRKAA21.12313274
47BCR1.10254091
48FGFR21.09125006
49TLK11.09083452
50MAP3K101.07789750
51JAK21.06554086
52PBK1.06003935
53TBK11.00823432
54PRKCE0.97490831
55RPS6KB20.94408284
56PRKCI0.92631021
57CDK80.91360955
58MAP2K30.89299852
59PNCK0.88954499
60MAP3K140.87666497
61MAPK40.87031100
62PRKCZ0.86878641
63RIPK10.84622863
64CDK60.80877357
65ERBB30.80732406
66PINK10.80198712
67MAPK150.80077737
68FGFR10.80041882
69JAK10.79788364
70WNK30.78876453
71MAP2K60.77064344
72WNK40.76579069
73CHUK0.76207288
74PAK30.75605811
75MAP3K110.75442243
76EPHB10.74617080
77DYRK1B0.74567848
78GSK3A0.74315348
79PRKACG0.73384515
80PTK20.72861500
81PRKAA10.71767258
82PRKCG0.70771690
83TSSK60.70472055
84NME10.70278254
85EPHA20.69426826
86PHKG10.68118906
87PHKG20.68118906
88ADRBK10.66160180
89CAMK2G0.64108120
90MYLK0.64042993
91MAP2K10.63762460
92MAP2K20.61967832
93LIMK10.61333496
94CSK0.60894647
95CAMK2D0.60808601
96WEE10.60552131
97TIE10.58457420
98NEK60.57819917
99TESK20.55147298
100NEK10.53837166
101STK30.53345882
102MAPK120.52795511
103DAPK10.51948877
104EPHA30.51609273
105OXSR10.50812520
106SGK30.50405512
107EPHA40.50283814
108MAPKAPK50.49621110
109PDPK10.48954290
110IRAK30.47014553
111PDK40.46628852
112PDK30.46628852
113MAPK130.46345026
114NUAK10.44579871
115MAP2K70.44423030
116RPS6KB10.44185004
117NTRK30.44029395
118TGFBR20.43041126
119CAMK1D0.42886790
120CDK40.42044264
121CSNK1D0.41299700
122MAP3K40.41272919
123PRKCQ0.40845270
124TAF10.40026926
125GRK10.39926199
126IGF1R0.38973523
127CSNK1E0.38973491
128CSNK1G10.38657857
129PRKG20.38561392
130ILK0.38331305
131CSNK1A10.38218043
132AKT30.37177236
133BMX0.36675870
134CDK70.36378450
135MAPK70.35521654
136MTOR0.35422667
137ICK0.34546641
138PIK3CA0.33838977
139MKNK20.33660302
140CSF1R0.33347921
141IKBKE0.32710212
142MAP3K50.32121281
143PRKCA0.32072044
144LATS20.31143064
145PRKACA0.31129561
146EGFR0.31067816
147CSNK2A10.30586572
148SGK4940.29960046
149SGK2230.29960046
150TAOK20.29753721
151FGFR30.29702235
152CSNK1A1L0.29642225
153MAP3K20.29071448
154RET0.28919757
155STK380.28224499
156ACVR1B0.28181958
157MAP3K10.27244481
158PDK10.27181904

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.28631575
2Nitrogen metabolism_Homo sapiens_hsa009103.48386816
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.47026360
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.26216676
5Arginine biosynthesis_Homo sapiens_hsa002202.95477379
6Tryptophan metabolism_Homo sapiens_hsa003802.70681177
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.66339361
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.57464850
9Complement and coagulation cascades_Homo sapiens_hsa046102.56859264
10Fatty acid degradation_Homo sapiens_hsa000712.51581312
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.50710376
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.43508733
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.34476629
14Butanoate metabolism_Homo sapiens_hsa006502.25431370
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.13121163
16Peroxisome_Homo sapiens_hsa041462.07336761
17Propanoate metabolism_Homo sapiens_hsa006401.96334350
18Chemical carcinogenesis_Homo sapiens_hsa052041.94226331
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.90545258
20Histidine metabolism_Homo sapiens_hsa003401.90117763
21Steroid hormone biosynthesis_Homo sapiens_hsa001401.83130616
22PPAR signaling pathway_Homo sapiens_hsa033201.83060399
23Fatty acid metabolism_Homo sapiens_hsa012121.77913742
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.74111154
25Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.72563264
26beta-Alanine metabolism_Homo sapiens_hsa004101.71508675
27Retinol metabolism_Homo sapiens_hsa008301.67437005
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.66736826
29Selenocompound metabolism_Homo sapiens_hsa004501.64764666
30Caffeine metabolism_Homo sapiens_hsa002321.62532270
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.61670046
32Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.61387818
33Staphylococcus aureus infection_Homo sapiens_hsa051501.56993030
34Bile secretion_Homo sapiens_hsa049761.55114138
35Sulfur metabolism_Homo sapiens_hsa009201.52503899
36Phenylalanine metabolism_Homo sapiens_hsa003601.50275499
37Pyruvate metabolism_Homo sapiens_hsa006201.47276688
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.43906612
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.39672431
40Tyrosine metabolism_Homo sapiens_hsa003501.39162648
41Starch and sucrose metabolism_Homo sapiens_hsa005001.33596319
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.28831606
43Fat digestion and absorption_Homo sapiens_hsa049751.28793151
44Folate biosynthesis_Homo sapiens_hsa007901.26369279
45Fatty acid elongation_Homo sapiens_hsa000621.26053733
46Biosynthesis of amino acids_Homo sapiens_hsa012301.24321117
47Carbon metabolism_Homo sapiens_hsa012001.23721450
48Steroid biosynthesis_Homo sapiens_hsa001001.18666886
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.14357978
50ABC transporters_Homo sapiens_hsa020101.13564576
51Maturity onset diabetes of the young_Homo sapiens_hsa049501.12107174
52Arginine and proline metabolism_Homo sapiens_hsa003301.02488919
53Vitamin digestion and absorption_Homo sapiens_hsa049771.00624981
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.98991560
55Sulfur relay system_Homo sapiens_hsa041220.94833777
56Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.94079841
57Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.92408171
58Vitamin B6 metabolism_Homo sapiens_hsa007500.87533958
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.84856790
60Lysine degradation_Homo sapiens_hsa003100.84853266
61Glutathione metabolism_Homo sapiens_hsa004800.83949590
62Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.80443762
63One carbon pool by folate_Homo sapiens_hsa006700.79490224
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.78286423
65Ether lipid metabolism_Homo sapiens_hsa005650.75012178
66Glycerolipid metabolism_Homo sapiens_hsa005610.73523183
67Pentose phosphate pathway_Homo sapiens_hsa000300.72574179
68Sphingolipid metabolism_Homo sapiens_hsa006000.65370477
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.64178058
70Protein export_Homo sapiens_hsa030600.57057966
71Metabolic pathways_Homo sapiens_hsa011000.49221904
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.48218648
73Fatty acid biosynthesis_Homo sapiens_hsa000610.44633609
74N-Glycan biosynthesis_Homo sapiens_hsa005100.43392765
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40274469
76Fructose and mannose metabolism_Homo sapiens_hsa000510.39983111
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.39390890
78Phototransduction_Homo sapiens_hsa047440.38642306
79RNA polymerase_Homo sapiens_hsa030200.35857837
80Galactose metabolism_Homo sapiens_hsa000520.32627908
81alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29624121
82Prion diseases_Homo sapiens_hsa050200.26391995
83Linoleic acid metabolism_Homo sapiens_hsa005910.22815586
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19575530
85Insulin resistance_Homo sapiens_hsa049310.18705472
86Proteasome_Homo sapiens_hsa030500.17709997
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.17662398
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17127545
89Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.13976758
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.13773548
91Pancreatic secretion_Homo sapiens_hsa049720.09859046
92Pyrimidine metabolism_Homo sapiens_hsa002400.08770084
93Basal transcription factors_Homo sapiens_hsa030220.08722573
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.06761449
95Glucagon signaling pathway_Homo sapiens_hsa049220.05330712
96Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.02681048
97AMPK signaling pathway_Homo sapiens_hsa041520.00435962
98Oxidative phosphorylation_Homo sapiens_hsa00190-0.2524224
99Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.2457676
100Bladder cancer_Homo sapiens_hsa05219-0.2035344
101Regulation of autophagy_Homo sapiens_hsa04140-0.2032496
102African trypanosomiasis_Homo sapiens_hsa05143-0.1912968
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.1871741
104Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1685572
105Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1678613
106Hepatitis C_Homo sapiens_hsa05160-0.1517402
107Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1460620
108Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1325781
109Insulin signaling pathway_Homo sapiens_hsa04910-0.1307427
110Protein digestion and absorption_Homo sapiens_hsa04974-0.1139423
111Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1082713
112Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1080697
113Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1019491
114Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0954576
115Mineral absorption_Homo sapiens_hsa04978-0.0738732
116Renin-angiotensin system_Homo sapiens_hsa04614-0.0260564

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