DNLZ

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.16901788
2mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.02901582
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.94590501
4ATP synthesis coupled proton transport (GO:0015986)5.94590501
5respiratory electron transport chain (GO:0022904)5.58847105
6electron transport chain (GO:0022900)5.45383988
7base-excision repair, AP site formation (GO:0006285)5.00637642
8regulation of mitochondrial translation (GO:0070129)4.99852606
9pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.98260054
10establishment of protein localization to mitochondrial membrane (GO:0090151)4.93106386
11DNA deamination (GO:0045006)4.92732575
12viral transcription (GO:0019083)4.89596355
13translational termination (GO:0006415)4.68636587
14SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.48365826
15chaperone-mediated protein transport (GO:0072321)4.43795654
16cotranslational protein targeting to membrane (GO:0006613)4.42234206
17protein targeting to ER (GO:0045047)4.40844354
18mitochondrial calcium ion transport (GO:0006851)4.30842830
19establishment of protein localization to endoplasmic reticulum (GO:0072599)4.19379455
20pyrimidine nucleotide catabolic process (GO:0006244)4.17809040
21translational elongation (GO:0006414)4.17502227
22regulation of oxidative phosphorylation (GO:0002082)4.16558559
23protein localization to endoplasmic reticulum (GO:0070972)4.14226503
24protein complex biogenesis (GO:0070271)4.11874307
25water-soluble vitamin biosynthetic process (GO:0042364)4.11486147
26oxidative phosphorylation (GO:0006119)3.88561001
27mitochondrial respiratory chain complex assembly (GO:0033108)3.84317763
28ribosomal small subunit assembly (GO:0000028)3.83276552
29deoxyribonucleotide catabolic process (GO:0009264)3.80454853
30metallo-sulfur cluster assembly (GO:0031163)3.72937456
31iron-sulfur cluster assembly (GO:0016226)3.72937456
32negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.70792198
33cellular component biogenesis (GO:0044085)3.69871086
34viral life cycle (GO:0019058)3.66311357
35mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.65198887
36mitochondrial respiratory chain complex I assembly (GO:0032981)3.65198887
37NADH dehydrogenase complex assembly (GO:0010257)3.65198887
38cellular protein complex disassembly (GO:0043624)3.61606464
39ribosomal small subunit biogenesis (GO:0042274)3.56070330
40ribonucleoprotein complex biogenesis (GO:0022613)3.55203772
41protein maturation by protein folding (GO:0022417)3.55123522
42pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.53282556
43negative regulation of telomere maintenance (GO:0032205)3.53010370
44behavioral response to nicotine (GO:0035095)3.45537362
45deoxyribose phosphate catabolic process (GO:0046386)3.42227385
46translational initiation (GO:0006413)3.40059228
47pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.38311068
48protein-cofactor linkage (GO:0018065)3.36689368
49GDP-mannose metabolic process (GO:0019673)3.36449969
50positive regulation of T cell apoptotic process (GO:0070234)3.33788212
51L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.33704444
52pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.32368281
53pseudouridine synthesis (GO:0001522)3.32154597
54respiratory chain complex IV assembly (GO:0008535)3.30066405
55GTP biosynthetic process (GO:0006183)3.29948483
56purine nucleoside triphosphate biosynthetic process (GO:0009145)3.26575633
57nuclear-transcribed mRNA catabolic process (GO:0000956)3.26391511
58purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.25590948
59positive regulation of lymphocyte apoptotic process (GO:0070230)3.25189728
60ATP biosynthetic process (GO:0006754)3.24345939
61heme biosynthetic process (GO:0006783)3.24126313
62negative regulation of microtubule polymerization (GO:0031115)3.22482568
63hypothalamus development (GO:0021854)3.20844260
64positive regulation of protein homooligomerization (GO:0032464)3.18904562
65translation (GO:0006412)3.18757693
66nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.17244894
67protein complex disassembly (GO:0043241)3.16872048
68cytochrome complex assembly (GO:0017004)3.13830893
69purine deoxyribonucleotide catabolic process (GO:0009155)3.13028000
70protein targeting to mitochondrion (GO:0006626)3.12221987
71mRNA catabolic process (GO:0006402)3.09274025
72protein targeting to membrane (GO:0006612)3.09248098
73macromolecular complex disassembly (GO:0032984)3.07529382
74rRNA modification (GO:0000154)3.07452863
75viral protein processing (GO:0019082)3.06130185
76ribonucleoside triphosphate biosynthetic process (GO:0009201)3.05306152
77protein insertion into membrane (GO:0051205)3.02451851
78negative regulation of cell size (GO:0045792)2.96997405
79rRNA processing (GO:0006364)2.96950345
80platelet dense granule organization (GO:0060155)2.96734561
81UTP biosynthetic process (GO:0006228)2.96452694
82heterochromatin organization (GO:0070828)2.96354117
83hydrogen ion transmembrane transport (GO:1902600)2.94003402
84regulation of protein heterodimerization activity (GO:0043497)2.93950506
85regulation of telomerase activity (GO:0051972)2.92015828
86polyketide metabolic process (GO:0030638)2.91793150
87doxorubicin metabolic process (GO:0044598)2.91793150
88daunorubicin metabolic process (GO:0044597)2.91793150
89RNA catabolic process (GO:0006401)2.91288483
90pteridine-containing compound biosynthetic process (GO:0042559)2.91276218
91tRNA modification (GO:0006400)2.90970745
92UTP metabolic process (GO:0046051)2.90968218
93intracellular protein transmembrane import (GO:0044743)2.90416261
94establishment of protein localization to mitochondrion (GO:0072655)2.90308935
95pattern specification involved in kidney development (GO:0061004)2.89651208
96establishment of protein localization to membrane (GO:0090150)2.89049870
97negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.88916625
98galactose catabolic process (GO:0019388)2.87868305
99peptidyl-histidine modification (GO:0018202)2.87856752
100sarcomere organization (GO:0045214)2.86576042
101ubiquinone biosynthetic process (GO:0006744)2.85812867
102quinone biosynthetic process (GO:1901663)2.85812867
103deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.83585570
104grooming behavior (GO:0007625)2.82836874
105modulation by virus of host process (GO:0019054)2.82729007
106CTP metabolic process (GO:0046036)2.82264641
107CTP biosynthetic process (GO:0006241)2.82264641
108rRNA metabolic process (GO:0016072)2.82018337
109maturation of SSU-rRNA (GO:0030490)2.79567355
110guanosine-containing compound biosynthetic process (GO:1901070)2.79515387
111DNA damage response, detection of DNA damage (GO:0042769)2.79473705
112termination of RNA polymerase III transcription (GO:0006386)2.78811491
113transcription elongation from RNA polymerase III promoter (GO:0006385)2.78811491
114signal peptide processing (GO:0006465)2.78644147
115NADH metabolic process (GO:0006734)2.77802560
116cellular response to nicotine (GO:0071316)2.75578462
117proteasome assembly (GO:0043248)2.74727103
118tricarboxylic acid cycle (GO:0006099)2.72696993
119nucleoside triphosphate biosynthetic process (GO:0009142)2.69305197
120protein localization to mitochondrion (GO:0070585)2.67284477
121inner mitochondrial membrane organization (GO:0007007)2.65462936
122protein neddylation (GO:0045116)2.64601287
123regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.63799366
124aerobic respiration (GO:0009060)2.63049596
125mitochondrial transport (GO:0006839)2.60900635
126pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.60879984
127amino acid salvage (GO:0043102)2.60523664
128L-methionine salvage (GO:0071267)2.60523664
129L-methionine biosynthetic process (GO:0071265)2.60523664
130pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.58989922
131regulation of cellular respiration (GO:0043457)2.58304264
132ribosomal large subunit biogenesis (GO:0042273)2.56003559
133proton transport (GO:0015992)2.55238338
134porphyrin-containing compound biosynthetic process (GO:0006779)2.53432516
135regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.51181634
136tetrapyrrole biosynthetic process (GO:0033014)2.50707132
137nucleobase-containing small molecule interconversion (GO:0015949)2.50459855
138detection of temperature stimulus involved in sensory perception (GO:0050961)2.49467956
139detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.49467956
140hydrogen transport (GO:0006818)2.48394841
141erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.47858428

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.30480728
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.12518806
3NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.36661438
4EZH2_22144423_ChIP-Seq_EOC_Human3.10690633
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.00640296
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.91106108
7MYC_18555785_ChIP-Seq_MESCs_Mouse2.82742265
8ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.60671784
9CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.59896452
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.55588368
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.54590939
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.41104480
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.35911091
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.32967418
15SRY_22984422_ChIP-ChIP_TESTIS_Rat2.15393728
16XRN2_22483619_ChIP-Seq_HELA_Human2.10520554
17CREB1_15753290_ChIP-ChIP_HEK293T_Human1.98508372
18THAP11_20581084_ChIP-Seq_MESCs_Mouse1.97292915
19* LXR_22292898_ChIP-Seq_THP-1_Human1.95838359
20CTCF_18555785_ChIP-Seq_MESCs_Mouse1.94845359
21STAT6_21828071_ChIP-Seq_BEAS2B_Human1.93676306
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.87185012
23DCP1A_22483619_ChIP-Seq_HELA_Human1.87121644
24TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84500003
25RARG_19884340_ChIP-ChIP_MEFs_Mouse1.76462233
26* YY1_22570637_ChIP-Seq_MALME-3M_Human1.73101400
27MYC_22102868_ChIP-Seq_BL_Human1.71956102
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69835303
29EST1_17652178_ChIP-ChIP_JURKAT_Human1.68212771
30CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.67517474
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.66195455
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65779690
33MYC_19079543_ChIP-ChIP_MESCs_Mouse1.63058707
34ZNF263_19887448_ChIP-Seq_K562_Human1.61075690
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.60635423
36PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.59045151
37TET1_21451524_ChIP-Seq_MESCs_Mouse1.58784604
38MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58561536
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.56518598
40* E2F1_20622854_ChIP-Seq_HELA_Human1.56243176
41* BCOR_27268052_Chip-Seq_Bcells_Human1.55350627
42* FOXP1_21924763_ChIP-Seq_HESCs_Human1.55309998
43MYC_19030024_ChIP-ChIP_MESCs_Mouse1.54122614
44JARID2_20075857_ChIP-Seq_MESCs_Mouse1.53519345
45MAF_26560356_Chip-Seq_TH2_Human1.53281528
46GABP_19822575_ChIP-Seq_HepG2_Human1.51765201
47YY1_21170310_ChIP-Seq_MESCs_Mouse1.51259044
48TTF2_22483619_ChIP-Seq_HELA_Human1.48455031
49FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.44491496
50SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.44128206
51JARID2_20064375_ChIP-Seq_MESCs_Mouse1.42870174
52PHF8_20622854_ChIP-Seq_HELA_Human1.42673315
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42058572
54CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.40699389
55SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.40068207
56ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.39833246
57CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.39009588
58* VDR_21846776_ChIP-Seq_THP-1_Human1.36860901
59EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.36341900
60CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.32373189
61RACK7_27058665_Chip-Seq_MCF-7_Human1.32135022
62CTCF_27219007_Chip-Seq_ERYTHROID_Human1.31818964
63FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.31818533
64ERG_21242973_ChIP-ChIP_JURKAT_Human1.31576015
65TP53_20018659_ChIP-ChIP_R1E_Mouse1.29149423
66* CIITA_25753668_ChIP-Seq_RAJI_Human1.29006406
67SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.28120446
68* BCL6_27268052_Chip-Seq_Bcells_Human1.27208582
69SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.27146470
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.26995761
71TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26598452
72ZFP281_18757296_ChIP-ChIP_E14_Mouse1.26557614
73SA1_27219007_Chip-Seq_ERYTHROID_Human1.26373744
74ELF1_17652178_ChIP-ChIP_JURKAT_Human1.25605963
75ELF1_20517297_ChIP-Seq_JURKAT_Human1.23913982
76CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.22772930
77TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.22386531
78SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22052182
79PU.1_20513432_ChIP-Seq_Bcells_Mouse1.21987842
80EZH2_27304074_Chip-Seq_ESCs_Mouse1.21300749
81KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.20451990
82THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.19299973
83UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.18001859
84* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.17700771
85EZH2_18974828_ChIP-Seq_MESCs_Mouse1.17139427
86RNF2_18974828_ChIP-Seq_MESCs_Mouse1.17139427
87TBX5_21415370_ChIP-Seq_HL-1_Mouse1.15822202
88SMC3_22415368_ChIP-Seq_MEFs_Mouse1.15430640
89P68_20966046_ChIP-Seq_HELA_Human1.14829159
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.14513087
91KDM2B_26808549_Chip-Seq_DND41_Human1.14242725
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13590928
93* SMC4_20622854_ChIP-Seq_HELA_Human1.13157123
94ELK3_25401928_ChIP-Seq_HUVEC_Human1.12944393
95CTCF_27219007_Chip-Seq_Bcells_Human1.12162267
96CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.11319390
97KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11246888
98SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.11075064
99NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10265243
100VDR_23849224_ChIP-Seq_CD4+_Human1.09855658
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09569550
102KDM5A_27292631_Chip-Seq_BREAST_Human1.09105314
103RARB_24833708_ChIP-Seq_LIVER_Mouse1.09079758
104MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.08527749
105ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.08304043
106SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08271560
107SA1_27219007_Chip-Seq_Bcells_Human1.08247132
108NOTCH1_21737748_ChIP-Seq_TLL_Human1.07871478
109SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.07295697
110CTCF_26484167_Chip-Seq_Bcells_Mouse1.07077851
111SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.06815348
112* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.06511719
113TP53_22127205_ChIP-Seq_IMR90_Human1.06215426
114* P300_27268052_Chip-Seq_Bcells_Human1.06195473
115CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.05350794
116NELFA_20434984_ChIP-Seq_ESCs_Mouse1.04044869
117* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.04039716
118PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.03840990
119CTCF_20526341_ChIP-Seq_ESCs_Human1.03659062
120CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.03419194
121CTCF_21964334_Chip-Seq_Bcells_Human1.03257888
122KDM2B_26808549_Chip-Seq_SUP-B15_Human1.02772616
123DNAJC2_21179169_ChIP-ChIP_NT2_Human1.02519063
124FOXP3_21729870_ChIP-Seq_TREG_Human1.02216578
125ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.01846476
126SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.01813418
127ERG_20887958_ChIP-Seq_HPC-7_Mouse1.01165111
128RARA_24833708_ChIP-Seq_LIVER_Mouse1.01131920
129ELK1_22589737_ChIP-Seq_MCF10A_Human1.01067584
130CTCF_21964334_ChIP-Seq_BJAB-B_Human0.99908916
131* VDR_24763502_ChIP-Seq_THP-1_Human0.98409729

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003283_abnormal_digestive_organ3.90498133
2MP0009379_abnormal_foot_pigmentation3.90185539
3MP0000751_myopathy3.50527091
4MP0003646_muscle_fatigue3.38477112
5MP0002837_dystrophic_cardiac_calcinosis3.35595077
6MP0006276_abnormal_autonomic_nervous3.14831584
7MP0002653_abnormal_ependyma_morphology3.05215125
8MP0001986_abnormal_taste_sensitivity2.90714917
9MP0000749_muscle_degeneration2.89320644
10MP0005423_abnormal_somatic_nervous2.85382499
11MP0001188_hyperpigmentation2.74189645
12MP0006036_abnormal_mitochondrial_physio2.43218471
13MP0004145_abnormal_muscle_electrophysio2.39383786
14MP0003137_abnormal_impulse_conducting2.38175357
15MP0003123_paternal_imprinting2.03618922
16MP0005330_cardiomyopathy1.99756871
17MP0004859_abnormal_synaptic_plasticity1.99741578
18MP0001919_abnormal_reproductive_system1.83931738
19MP0010030_abnormal_orbit_morphology1.81045049
20MP0004215_abnormal_myocardial_fiber1.79432998
21MP0001968_abnormal_touch/_nociception1.76221290
22MP0005083_abnormal_biliary_tract1.73617757
23MP0005174_abnormal_tail_pigmentation1.73162217
24MP0000759_abnormal_skeletal_muscle1.69893029
25MP0005394_taste/olfaction_phenotype1.66410355
26MP0005499_abnormal_olfactory_system1.66410355
27MP0001529_abnormal_vocalization1.64461130
28MP0000049_abnormal_middle_ear1.64214365
29MP0002909_abnormal_adrenal_gland1.63438535
30MP0004142_abnormal_muscle_tone1.63199633
31MP0004858_abnormal_nervous_system1.63012003
32MP0004270_analgesia1.62927232
33MP0002089_abnormal_postnatal_growth/wei1.61478538
34MP0005646_abnormal_pituitary_gland1.61171300
35MP0000747_muscle_weakness1.55898802
36MP0002269_muscular_atrophy1.50340877
37MP0002736_abnormal_nociception_after1.49669483
38MP0000750_abnormal_muscle_regeneration1.47068614
39MP0001542_abnormal_bone_strength1.47034235
40MP0008789_abnormal_olfactory_epithelium1.46779899
41MP0002735_abnormal_chemical_nociception1.46449399
42MP0005084_abnormal_gallbladder_morpholo1.44882951
43MP0001873_stomach_inflammation1.44852199
44MP0000516_abnormal_urinary_system1.44164580
45MP0005367_renal/urinary_system_phenotyp1.44164580
46MP0009053_abnormal_anal_canal1.43237175
47MP0003787_abnormal_imprinting1.42963920
48MP0004510_myositis1.41829417
49MP0004036_abnormal_muscle_relaxation1.41310472
50MP0006292_abnormal_olfactory_placode1.41065135
51MP0008007_abnormal_cellular_replicative1.40429413
52MP0009333_abnormal_splenocyte_physiolog1.40216043
53MP0002184_abnormal_innervation1.39610646
54MP0002106_abnormal_muscle_physiology1.39192096
55MP0004133_heterotaxia1.38514305
56MP0002277_abnormal_respiratory_mucosa1.35165537
57MP0003880_abnormal_central_pattern1.34256479
58MP0002272_abnormal_nervous_system1.29760043
59MP0004147_increased_porphyrin_level1.29290563
60MP0009046_muscle_twitch1.27882431
61MP0002734_abnormal_mechanical_nocicepti1.27064956
62MP0004130_abnormal_muscle_cell1.26554047
63MP0005501_abnormal_skin_physiology1.26207712
64MP0004233_abnormal_muscle_weight1.25770659
65MP0003656_abnormal_erythrocyte_physiolo1.25598557
66MP0004087_abnormal_muscle_fiber1.24945545
67MP0004084_abnormal_cardiac_muscle1.24373613
68MP0005171_absent_coat_pigmentation1.23447140
69MP0006035_abnormal_mitochondrial_morpho1.22967414
70MP0005379_endocrine/exocrine_gland_phen1.20878076
71MP0003315_abnormal_perineum_morphology1.20865207
72MP0005369_muscle_phenotype1.20346214
73MP0003635_abnormal_synaptic_transmissio1.20086704
74MP0002751_abnormal_autonomic_nervous1.19242811
75MP0001756_abnormal_urination1.18910116
76MP0003942_abnormal_urinary_system1.18557253
77MP0001905_abnormal_dopamine_level1.18453767
78MP0000013_abnormal_adipose_tissue1.18272271
79MP0003806_abnormal_nucleotide_metabolis1.16702830
80MP0004742_abnormal_vestibular_system1.15914405
81MP0000955_abnormal_spinal_cord1.15707093
82MP0005220_abnormal_exocrine_pancreas1.15020654
83MP0008875_abnormal_xenobiotic_pharmacok1.14150978
84MP0001348_abnormal_lacrimal_gland1.13887640
85MP0002138_abnormal_hepatobiliary_system1.12961283
86MP0002972_abnormal_cardiac_muscle1.12365490
87MP0001970_abnormal_pain_threshold1.12216865
88MP0005389_reproductive_system_phenotype1.11641784
89MP0009250_abnormal_appendicular_skeleto1.09324989
90MP0008058_abnormal_DNA_repair1.08602185
91MP0004085_abnormal_heartbeat1.07267842
92MP0002733_abnormal_thermal_nociception1.07035811
93MP0000537_abnormal_urethra_morphology1.07022214
94MP0000678_abnormal_parathyroid_gland1.05749014
95MP0000470_abnormal_stomach_morphology1.04828316
96MP0002928_abnormal_bile_duct1.04094178
97MP0001270_distended_abdomen1.04003888
98MP0005620_abnormal_muscle_contractility1.03283795
99MP0003959_abnormal_lean_body1.01710540
100MP0003121_genomic_imprinting1.01004525
101MP0002557_abnormal_social/conspecific_i1.00985038
102MP0000631_abnormal_neuroendocrine_gland1.00814602
103MP0001664_abnormal_digestion0.98904921
104MP0003879_abnormal_hair_cell0.98835625
105MP0003186_abnormal_redox_activity0.97383278
106MP0002249_abnormal_larynx_morphology0.95611594
107MP0000538_abnormal_urinary_bladder0.92690773
108MP0005636_abnormal_mineral_homeostasis0.92600173
109MP0000778_abnormal_nervous_system0.92067617
110MP0001944_abnormal_pancreas_morphology0.91299332
111MP0000358_abnormal_cell_content/0.90411446
112MP0000343_altered_response_to0.90216805
113MP0002067_abnormal_sensory_capabilities0.89739168
114MP0001440_abnormal_grooming_behavior0.89109997
115MP0008438_abnormal_cutaneous_collagen0.88135719
116MP0005645_abnormal_hypothalamus_physiol0.88119448
117MP0002064_seizures0.87426392
118MP0001299_abnormal_eye_distance/0.86703610
119MP0002693_abnormal_pancreas_physiology0.86479521
120MP0005387_immune_system_phenotype0.86169650
121MP0001790_abnormal_immune_system0.86169650
122MP0003122_maternal_imprinting0.85999848
123MP0005381_digestive/alimentary_phenotyp0.85794706
124MP0003878_abnormal_ear_physiology0.85500693
125MP0005377_hearing/vestibular/ear_phenot0.85500693
126MP0005584_abnormal_enzyme/coenzyme_acti0.84812543
127MP0003786_premature_aging0.84458569
128MP0002160_abnormal_reproductive_system0.83831276
129MP0009745_abnormal_behavioral_response0.83584616
130MP0009840_abnormal_foam_cell0.82887168
131MP0000015_abnormal_ear_pigmentation0.80587322
132MP0002139_abnormal_hepatobiliary_system0.80364204
133MP0002078_abnormal_glucose_homeostasis0.79959135
134MP0005385_cardiovascular_system_phenoty0.79540517
135MP0001544_abnormal_cardiovascular_syste0.79540517
136MP0003111_abnormal_nucleus_morphology0.79478889
137MP0001502_abnormal_circadian_rhythm0.78944386
138MP0003221_abnormal_cardiomyocyte_apopto0.78495106
139MP0006072_abnormal_retinal_apoptosis0.77160986
140MP0003948_abnormal_gas_homeostasis0.77160736
141MP0004811_abnormal_neuron_physiology0.77060464
142MP0009697_abnormal_copulation0.76059118
143MP0002066_abnormal_motor_capabilities/c0.74764596
144MP0004885_abnormal_endolymph0.74386921
145MP0003329_amyloid_beta_deposits0.74384465
146MP0001663_abnormal_digestive_system0.74326887
147MP0003011_delayed_dark_adaptation0.72421800
148MP0008873_increased_physiological_sensi0.72207413
149MP0005595_abnormal_vascular_smooth0.71864925
150MP0002063_abnormal_learning/memory/cond0.71542607
151MP0002163_abnormal_gland_morphology0.71474332
152MP0001485_abnormal_pinna_reflex0.71212365
153MP0003119_abnormal_digestive_system0.70981314
154MP0005332_abnormal_amino_acid0.68939015
155MP0005075_abnormal_melanosome_morpholog0.68464413
156MP0001881_abnormal_mammary_gland0.67937846
157MP0004957_abnormal_blastocyst_morpholog0.65832681
158MP0000490_abnormal_crypts_of0.65779976
159MP0001727_abnormal_embryo_implantation0.65124617
160MP0009765_abnormal_xenobiotic_induced0.64952863
161MP0002177_abnormal_outer_ear0.64916482
162MP0000462_abnormal_digestive_system0.64862338
163MP0002210_abnormal_sex_determination0.62101587
164MP0000313_abnormal_cell_death0.61516226
165MP0003693_abnormal_embryo_hatching0.60759311
166MP0000685_abnormal_immune_system0.60630474
167MP0002148_abnormal_hypersensitivity_rea0.60231205

Predicted human phenotypes

RankGene SetZ-score
1Hepatocellular necrosis (HP:0001404)5.65406821
2Acute necrotizing encephalopathy (HP:0006965)5.57333923
3Mitochondrial inheritance (HP:0001427)5.37122658
4Abnormal mitochondria in muscle tissue (HP:0008316)5.32639655
5Hepatic necrosis (HP:0002605)5.24815333
6Acute encephalopathy (HP:0006846)4.86023228
7Increased CSF lactate (HP:0002490)4.55629706
8Progressive macrocephaly (HP:0004481)4.33032101
9Decreased activity of mitochondrial respiratory chain (HP:0008972)4.26106795
10Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.26106795
11Increased hepatocellular lipid droplets (HP:0006565)3.82251945
12Lipid accumulation in hepatocytes (HP:0006561)3.79750139
13Increased intramyocellular lipid droplets (HP:0012240)3.78600956
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.74466877
15Respiratory failure (HP:0002878)3.66221110
16Lactic acidosis (HP:0003128)3.62212561
17Increased muscle lipid content (HP:0009058)3.62074635
18Cerebral edema (HP:0002181)3.53916694
19Exercise intolerance (HP:0003546)3.32171082
20Sudden death (HP:0001699)3.31437707
21Increased serum lactate (HP:0002151)3.30123302
22Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.19431007
23Neuroendocrine neoplasm (HP:0100634)3.09475925
24Pallor (HP:0000980)3.01015365
25Palpitations (HP:0001962)2.88229237
26Rib fusion (HP:0000902)2.85794867
27Emotional lability (HP:0000712)2.84732801
28Exertional dyspnea (HP:0002875)2.84160807
29Pheochromocytoma (HP:0002666)2.83085347
30Renal Fanconi syndrome (HP:0001994)2.81985784
31Rectal fistula (HP:0100590)2.79598669
32Rectovaginal fistula (HP:0000143)2.79598669
33Ragged-red muscle fibers (HP:0003200)2.75068921
34Absent thumb (HP:0009777)2.69952952
35CNS demyelination (HP:0007305)2.66566348
36Myoglobinuria (HP:0002913)2.65927786
37Concave nail (HP:0001598)2.60211354
38Poor suck (HP:0002033)2.59526379
39Myotonia (HP:0002486)2.58101697
40Aplasia/Hypoplasia of the patella (HP:0006498)2.56574329
41Neoplasm of the peripheral nervous system (HP:0100007)2.52859096
42Muscle hypertrophy of the lower extremities (HP:0008968)2.51567710
43Abnormality of aromatic amino acid family metabolism (HP:0004338)2.50715004
44Squamous cell carcinoma (HP:0002860)2.50068905
45Hyperphosphaturia (HP:0003109)2.49507670
46Abnormality of alanine metabolism (HP:0010916)2.47789126
47Hyperalaninemia (HP:0003348)2.47789126
48Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.47789126
49Microretrognathia (HP:0000308)2.45203635
50Optic disc pallor (HP:0000543)2.44290987
51Abnormality of glycolysis (HP:0004366)2.42835462
52Increased serum pyruvate (HP:0003542)2.42835462
53Leukodystrophy (HP:0002415)2.40565993
54Myokymia (HP:0002411)2.38595140
55Vaginal fistula (HP:0004320)2.38082571
56Mesangial abnormality (HP:0001966)2.37865525
57Abnormality of renal resorption (HP:0011038)2.37849970
58Hyperthyroidism (HP:0000836)2.37280556
59Lethargy (HP:0001254)2.35785943
60Calf muscle hypertrophy (HP:0008981)2.35698813
61Paralysis (HP:0003470)2.35403673
62Exercise-induced myalgia (HP:0003738)2.34995426
63Retinal dysplasia (HP:0007973)2.34251472
64Patellar aplasia (HP:0006443)2.32967196
65Opisthotonus (HP:0002179)2.31953250
66Respiratory difficulties (HP:0002880)2.31441198
67Aplasia/Hypoplasia of the sacrum (HP:0008517)2.31259306
68Type I transferrin isoform profile (HP:0003642)2.30930405
69Rhabdomyolysis (HP:0003201)2.27319375
70Ketosis (HP:0001946)2.24743585
71Intestinal fistula (HP:0100819)2.21419396
72Methylmalonic aciduria (HP:0012120)2.19163250
73Rectal prolapse (HP:0002035)2.16224294
74Cerebral hypomyelination (HP:0006808)2.15261082
75Athetosis (HP:0002305)2.14559885
76Abnormal urine phosphate concentration (HP:0012599)2.13783582
77Progressive muscle weakness (HP:0003323)2.13453629
78Abnormality of reticulocytes (HP:0004312)2.13378175
79Congenital, generalized hypertrichosis (HP:0004540)2.13099199
80Ketoacidosis (HP:0001993)2.12425239
81Supraventricular tachycardia (HP:0004755)2.10045942
82Reticulocytopenia (HP:0001896)2.08830964
83Distal arthrogryposis (HP:0005684)2.07018571
84Late onset (HP:0003584)2.06805851
85Deep palmar crease (HP:0006191)2.06244471
86Supraventricular arrhythmia (HP:0005115)2.05075006
87Macrocytic anemia (HP:0001972)2.01365449
88Megalencephaly (HP:0001355)2.00335160
89Pendular nystagmus (HP:0012043)2.00228240
90Muscle fiber atrophy (HP:0100295)1.98925174
91Abnormal glycosylation (HP:0012345)1.98592511
92Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.98592511
93Abnormal protein N-linked glycosylation (HP:0012347)1.98592511
94Abnormal protein glycosylation (HP:0012346)1.98592511
95Progressive microcephaly (HP:0000253)1.97252731
96Abnormality of dicarboxylic acid metabolism (HP:0010995)1.95032084
97Dicarboxylic aciduria (HP:0003215)1.95032084
98Adenoma sebaceum (HP:0009720)1.94611294
99Angiofibromas (HP:0010615)1.94611294
100Abnormality of cells of the erythroid lineage (HP:0012130)1.92511181
101Primary atrial arrhythmia (HP:0001692)1.91304116
102EMG: myopathic abnormalities (HP:0003458)1.90962184
103Abnormality of the calf musculature (HP:0001430)1.89838078
104Prolonged QT interval (HP:0001657)1.88842505
105Type II lissencephaly (HP:0007260)1.87751919
106Muscle stiffness (HP:0003552)1.87014205
107Hypoplasia of the radius (HP:0002984)1.86618407
108Severe muscular hypotonia (HP:0006829)1.85942555
109Aplasia/Hypoplasia involving the musculature (HP:0001460)1.85398203
110Abnormal number of erythroid precursors (HP:0012131)1.85335281
111Achilles tendon contracture (HP:0001771)1.85191538
112Ventricular tachycardia (HP:0004756)1.85148649
113Atrial fibrillation (HP:0005110)1.84843340
114Testicular atrophy (HP:0000029)1.84790080
115Progressive neurologic deterioration (HP:0002344)1.82529160
116Neoplasm of the adrenal gland (HP:0100631)1.78917962
117Protrusio acetabuli (HP:0003179)1.77801266
118Slender long bone (HP:0003100)1.77672724
1193-Methylglutaconic aciduria (HP:0003535)1.77200948
120Redundant skin (HP:0001582)1.77167020
121Limb-girdle muscle atrophy (HP:0003797)1.76531053
122Lipoatrophy (HP:0100578)1.75551468
123Abnormality of the heme biosynthetic pathway (HP:0010472)1.75367372
124Ankle clonus (HP:0011448)1.74366883
125Abnormal sex determination (HP:0012244)1.74358870
126Sex reversal (HP:0012245)1.74358870
127Rough bone trabeculation (HP:0100670)1.74074382
128Abnormality of the Achilles tendon (HP:0005109)1.73794636
129Methylmalonic acidemia (HP:0002912)1.73691917
130Delusions (HP:0000746)1.73189613
131Myopathic facies (HP:0002058)1.73107750
132Diaphragmatic weakness (HP:0009113)1.72228193
133Abnormal EKG (HP:0003115)1.72049947
134J-shaped sella turcica (HP:0002680)1.71611525
135Abnormality of glycosphingolipid metabolism (HP:0004343)1.70774418
136Abnormality of glycolipid metabolism (HP:0010969)1.70774418
137Abnormality of liposaccharide metabolism (HP:0010968)1.70774418
138Neoplasm of head and neck (HP:0012288)1.70709216
139Esophageal neoplasm (HP:0100751)1.70709216
140Abnormality of the vocal cords (HP:0008777)1.70551340
141Conjunctival hamartoma (HP:0100780)1.70298999
142Glycosuria (HP:0003076)1.69752351
143Abnormality of urine glucose concentration (HP:0011016)1.69752351
144Increased serum ferritin (HP:0003281)1.66513680
145Abnormal trabecular bone morphology (HP:0100671)1.65805960
146Congenital stationary night blindness (HP:0007642)1.65174490
147Joint stiffness (HP:0001387)1.64943399
148Abnormal hemoglobin (HP:0011902)1.63735498
149Abnormality of the aortic arch (HP:0012303)1.63574889
150Acute lymphatic leukemia (HP:0006721)1.62400354
151Oral leukoplakia (HP:0002745)1.61460868
152Bulbous nose (HP:0000414)1.60621171
153Pancytopenia (HP:0001876)1.59002393
154Generalized aminoaciduria (HP:0002909)1.57669246

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK14.48876768
2TAOK23.97104898
3BCKDK3.57363275
4VRK23.39333887
5CDK193.29452876
6BUB13.17382854
7TESK23.11638146
8ARAF2.95364290
9NME22.76630032
10MAP3K112.58348932
11PIM22.43485397
12INSRR2.40117580
13TRIB32.36135209
14LIMK12.20006172
15NME12.17721487
16SCYL21.98092542
17EIF2AK11.97711927
18STK161.89861240
19IRAK31.79366877
20DAPK31.78674973
21BRAF1.72827588
22PHKG21.71034410
23PHKG11.71034410
24ILK1.69043003
25TAOK11.63646947
26MAP3K121.55560892
27MYLK1.54837925
28TAF11.50657412
29MUSK1.43317900
30EPHB21.43253242
31SIK31.40102799
32UHMK11.38337152
33SMG11.37887009
34DYRK31.35552896
35MINK11.35153808
36OBSCN1.34443171
37MAP2K61.33199862
38SIK21.28449675
39NTRK11.14882089
40IKBKB1.14383418
41KDR1.11871850
42LMTK21.11037457
43MAP2K31.03242496
44DYRK1B1.01471012
45MAP2K21.01381456
46PKN21.00426660
47ADRBK20.99305552
48MAPKAPK30.98431530
49CAMKK20.96719062
50MAP3K70.96263861
51MAP3K100.94727848
52MAPK130.91661566
53TESK10.90461967
54SIK10.89679076
55GRK60.87222639
56CAMK10.85506211
57DMPK0.85042726
58CAMKK10.83669698
59KSR10.80843435
60DYRK20.80584576
61MARK20.78616530
62AURKA0.77521966
63LATS20.76673827
64NUAK10.76179719
65RPS6KA50.71467510
66BLK0.71159562
67MAP4K10.70701546
68RAF10.70561362
69CHUK0.70173420
70FLT30.68556186
71NEK20.68507141
72MAP2K40.68455663
73MAP2K70.68165697
74CSNK1G30.68128211
75CAMK2G0.66713088
76TTN0.66111428
77WNK40.66066200
78CDK140.65578107
79CHEK20.65429507
80PRKD20.65352422
81PKN10.61761439
82MARK10.61754035
83PRKCI0.61172586
84CAMK2D0.60117262
85IRAK40.60045019
86MAPKAPK50.59901273
87LRRK20.59610636
88MAP3K50.57884632
89CAMK40.57162341
90FES0.57069564
91ERN10.57009861
92MAPK150.56930514
93RPS6KA60.56668820
94MAPK110.55286037
95IRAK20.54694448
96PAK10.54472779
97ROCK20.53257080
98RPS6KC10.53206248
99RPS6KL10.53206248
100CCNB10.53115604
101IRAK10.52999166
102CDK11A0.52633940
103PRKD10.52463896
104MAPK120.51964685
105PAK30.51747849
106STK40.49823487
107PAK40.49680173
108MAP2K10.49470602
109RPS6KB20.48213711
110DAPK10.47761283
111GRK10.47122478
112BRSK10.45452311
113ADRBK10.45288311
114ZAP700.43694478
115ABL20.42505872
116CDK180.41398648
117CSNK1G20.41328771
118ATR0.41273190
119MAP3K10.40629446
120PRKCZ0.40540212
121CDK150.39911870
122PRKD30.38120779
123TBK10.37978251
124PBK0.36368613
125MAPK40.36276060
126HIPK20.36244448
127VRK10.36113155
128WEE10.36037980
129CSNK2A10.35244367
130PRKCD0.35146913
131PASK0.35022017
132CSNK1G10.33042950
133PIK3CG0.32096976
134CDK80.32093470
135ROCK10.31976605
136CAMK2B0.31967901
137CSNK1A10.31738272
138RPS6KA20.31671821
139RPS6KA10.29930661
140CDC70.25820312
141PRKCG0.25485838
142PLK10.24667496

Predicted pathways (KEGG)

RankGene SetZ-score
1Parkinsons disease_Homo sapiens_hsa050125.05476161
2Oxidative phosphorylation_Homo sapiens_hsa001905.04252684
3Ribosome_Homo sapiens_hsa030104.34562981
4Alzheimers disease_Homo sapiens_hsa050103.45624254
5Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.14477447
6Cardiac muscle contraction_Homo sapiens_hsa042603.11675546
7Huntingtons disease_Homo sapiens_hsa050163.08331705
8Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.92379058
9Protein export_Homo sapiens_hsa030602.87297006
10Sulfur relay system_Homo sapiens_hsa041222.80754260
11Proteasome_Homo sapiens_hsa030502.39654834
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99654637
132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.96213507
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.94412485
15Collecting duct acid secretion_Homo sapiens_hsa049661.76305193
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.75148721
17Folate biosynthesis_Homo sapiens_hsa007901.69303639
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.64404647
19Butanoate metabolism_Homo sapiens_hsa006501.61050321
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.57557184
21Propanoate metabolism_Homo sapiens_hsa006401.50596913
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.50579181
23RNA polymerase_Homo sapiens_hsa030201.46311653
24Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.45180645
25Carbon metabolism_Homo sapiens_hsa012001.33293780
26Pyrimidine metabolism_Homo sapiens_hsa002401.32674852
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31277796
28Fanconi anemia pathway_Homo sapiens_hsa034601.24546175
29Pyruvate metabolism_Homo sapiens_hsa006201.23930984
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.16581094
31DNA replication_Homo sapiens_hsa030301.13682684
32Fatty acid elongation_Homo sapiens_hsa000621.12344478
33Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.02541820
34Sulfur metabolism_Homo sapiens_hsa009201.00879579
35Asthma_Homo sapiens_hsa053100.99332773
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.99034941
37Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.94526762
38Arginine and proline metabolism_Homo sapiens_hsa003300.91910257
39Basal transcription factors_Homo sapiens_hsa030220.90975143
40Fatty acid degradation_Homo sapiens_hsa000710.88806966
41Biosynthesis of amino acids_Homo sapiens_hsa012300.84446564
42Synaptic vesicle cycle_Homo sapiens_hsa047210.83862637
43Maturity onset diabetes of the young_Homo sapiens_hsa049500.81184671
44Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.79029075
45Dilated cardiomyopathy_Homo sapiens_hsa054140.77580807
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.76876744
47Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76833666
48Base excision repair_Homo sapiens_hsa034100.75937054
49Metabolic pathways_Homo sapiens_hsa011000.75344262
50Spliceosome_Homo sapiens_hsa030400.75008119
51Systemic lupus erythematosus_Homo sapiens_hsa053220.74181575
52SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72519169
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.71405469
54Pentose phosphate pathway_Homo sapiens_hsa000300.70379911
55One carbon pool by folate_Homo sapiens_hsa006700.69869298
56Purine metabolism_Homo sapiens_hsa002300.69168986
57Pentose and glucuronate interconversions_Homo sapiens_hsa000400.69081051
58Rheumatoid arthritis_Homo sapiens_hsa053230.68930765
59Vibrio cholerae infection_Homo sapiens_hsa051100.68635995
60beta-Alanine metabolism_Homo sapiens_hsa004100.67939617
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.67282176
62Galactose metabolism_Homo sapiens_hsa000520.66104619
63Epstein-Barr virus infection_Homo sapiens_hsa051690.63692601
64Peroxisome_Homo sapiens_hsa041460.63557836
65N-Glycan biosynthesis_Homo sapiens_hsa005100.62892010
66Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.62089464
67Cyanoamino acid metabolism_Homo sapiens_hsa004600.62033314
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.61543690
69Fatty acid metabolism_Homo sapiens_hsa012120.60291528
70Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.60183436
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59922703
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59868505
73Mismatch repair_Homo sapiens_hsa034300.59811053
74Allograft rejection_Homo sapiens_hsa053300.59403801
75RNA degradation_Homo sapiens_hsa030180.58495478
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57339697
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.56318641
78Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55842119
79RNA transport_Homo sapiens_hsa030130.55603278
80Hedgehog signaling pathway_Homo sapiens_hsa043400.55571290
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54357929
82Primary immunodeficiency_Homo sapiens_hsa053400.53344562
83Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.53129853
84Bladder cancer_Homo sapiens_hsa052190.52988421
85Starch and sucrose metabolism_Homo sapiens_hsa005000.52014644
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.51113308
87Olfactory transduction_Homo sapiens_hsa047400.50897269
88Insulin signaling pathway_Homo sapiens_hsa049100.50548826
89Type I diabetes mellitus_Homo sapiens_hsa049400.49182662
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.48684317
91Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48336679
92Fructose and mannose metabolism_Homo sapiens_hsa000510.47619944
93Insulin secretion_Homo sapiens_hsa049110.47207710
94Fat digestion and absorption_Homo sapiens_hsa049750.46286383
95VEGF signaling pathway_Homo sapiens_hsa043700.44615008
96Drug metabolism - other enzymes_Homo sapiens_hsa009830.44379939
97Cocaine addiction_Homo sapiens_hsa050300.42560863
98Gap junction_Homo sapiens_hsa045400.41723310
99Autoimmune thyroid disease_Homo sapiens_hsa053200.40556395
100Nicotine addiction_Homo sapiens_hsa050330.40274687
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.40243269
102mRNA surveillance pathway_Homo sapiens_hsa030150.39096358
103Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38119806
104Alcoholism_Homo sapiens_hsa050340.37792830
105Cholinergic synapse_Homo sapiens_hsa047250.36520536
106Dopaminergic synapse_Homo sapiens_hsa047280.36470918
107Regulation of autophagy_Homo sapiens_hsa041400.32358294
108Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.31818365
109Nucleotide excision repair_Homo sapiens_hsa034200.31553883
110Basal cell carcinoma_Homo sapiens_hsa052170.31034080
111Homologous recombination_Homo sapiens_hsa034400.30605984
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.30203969
113RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.29582414
114Oxytocin signaling pathway_Homo sapiens_hsa049210.28311590
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.27871255
116Thyroid cancer_Homo sapiens_hsa052160.27125342
117p53 signaling pathway_Homo sapiens_hsa041150.26238780
118Melanoma_Homo sapiens_hsa052180.24138280
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.24015341
120Herpes simplex infection_Homo sapiens_hsa051680.23617760
121Toll-like receptor signaling pathway_Homo sapiens_hsa046200.23156183
122Pancreatic secretion_Homo sapiens_hsa049720.22299766
123Tryptophan metabolism_Homo sapiens_hsa003800.20741960
124Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.20240101
125Apoptosis_Homo sapiens_hsa042100.19884397
126MAPK signaling pathway_Homo sapiens_hsa040100.19814996
127Lysosome_Homo sapiens_hsa041420.19390975
128HTLV-I infection_Homo sapiens_hsa051660.18210363
129Glutathione metabolism_Homo sapiens_hsa004800.18156068
130Selenocompound metabolism_Homo sapiens_hsa004500.18136168
131B cell receptor signaling pathway_Homo sapiens_hsa046620.17703230
132Glucagon signaling pathway_Homo sapiens_hsa049220.17595136
133Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.17498573
134Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.16006972
135Vascular smooth muscle contraction_Homo sapiens_hsa042700.15311292
136Melanogenesis_Homo sapiens_hsa049160.15049451
137Glycosaminoglycan degradation_Homo sapiens_hsa005310.14283652
138Morphine addiction_Homo sapiens_hsa050320.12847850
139Graft-versus-host disease_Homo sapiens_hsa053320.12379928
140Salmonella infection_Homo sapiens_hsa051320.11677374
141Viral carcinogenesis_Homo sapiens_hsa052030.09990715
142Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.09950437
143Shigellosis_Homo sapiens_hsa051310.09309314
144Transcriptional misregulation in cancer_Homo sapiens_hsa052020.08731152
145Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.06454809
146Cell cycle_Homo sapiens_hsa041100.06367770
147Sphingolipid metabolism_Homo sapiens_hsa006000.05807083
148Leishmaniasis_Homo sapiens_hsa051400.05179742
149Phagosome_Homo sapiens_hsa041450.05004539

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