DNM2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.23245084
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.23245084
3positive regulation of gamma-delta T cell activation (GO:0046645)4.96031476
4antigen processing and presentation of endogenous antigen (GO:0019883)4.67774563
5regulation of gamma-delta T cell differentiation (GO:0045586)4.47627568
6regulation of gamma-delta T cell activation (GO:0046643)4.04136201
7positive thymic T cell selection (GO:0045059)3.85868945
8regulation of interferon-beta biosynthetic process (GO:0045357)3.56056150
9positive regulation of histone deacetylation (GO:0031065)3.46293599
10detection of bacterium (GO:0016045)3.41987317
11detection of other organism (GO:0098543)3.41166410
12negative regulation of cell killing (GO:0031342)3.39314592
13negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.39314592
14regulation of interleukin-12 biosynthetic process (GO:0045075)3.36548297
15positive regulation of Cdc42 GTPase activity (GO:0043089)3.35654735
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.33873463
17positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.33838658
18response to peptidoglycan (GO:0032494)3.32777540
19positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.26835141
20antigen processing and presentation via MHC class Ib (GO:0002475)3.23109933
21negative T cell selection (GO:0043383)3.15263309
22negative thymic T cell selection (GO:0045060)3.09324565
23natural killer cell differentiation (GO:0001779)3.07205318
24thymic T cell selection (GO:0045061)3.06548249
25leukocyte aggregation (GO:0070486)3.04069943
26germinal center formation (GO:0002467)3.00121846
27JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.98857827
28negative regulation of erythrocyte differentiation (GO:0045647)2.98368313
29response to laminar fluid shear stress (GO:0034616)2.96967448
30Golgi transport vesicle coating (GO:0048200)2.95119997
31COPI coating of Golgi vesicle (GO:0048205)2.95119997
32regulation of leukocyte degranulation (GO:0043300)2.93738783
33modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.87858688
34positive regulation by organism of defense response of other organism involved in symbiotic interact2.87858688
35modulation by symbiont of host immune response (GO:0052553)2.87858688
36positive regulation by symbiont of host defense response (GO:0052509)2.87858688
37modulation by symbiont of host defense response (GO:0052031)2.87858688
38modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.87858688
39negative regulation of myotube differentiation (GO:0010832)2.87730218
40hepatocyte apoptotic process (GO:0097284)2.86036997
41protein localization to endosome (GO:0036010)2.84494767
42embryonic process involved in female pregnancy (GO:0060136)2.84461181
43regulation of B cell receptor signaling pathway (GO:0050855)2.82945804
44neutrophil activation involved in immune response (GO:0002283)2.80680589
45detection of external biotic stimulus (GO:0098581)2.80084028
46regulation of myeloid leukocyte mediated immunity (GO:0002886)2.79451348
47positive T cell selection (GO:0043368)2.79203392
483-UTR-mediated mRNA stabilization (GO:0070935)2.78740326
49regulation of histone H3-K27 methylation (GO:0061085)2.76337893
50positive regulation of B cell differentiation (GO:0045579)2.76289799
51positive regulation of interferon-alpha production (GO:0032727)2.74733131
52positive regulation of lamellipodium assembly (GO:0010592)2.74607478
53apoptotic cell clearance (GO:0043277)2.74020031
54regulation of mast cell degranulation (GO:0043304)2.72897311
55mannose metabolic process (GO:0006013)2.70248070
56positive regulation of protein deacetylation (GO:0090312)2.70059338
57leukocyte cell-cell adhesion (GO:0007159)2.69636647
58regulation of type I interferon-mediated signaling pathway (GO:0060338)2.68194411
59activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.66194026
60T cell selection (GO:0045058)2.63882881
61modulation by symbiont of host cellular process (GO:0044068)2.63426601
62response to muramyl dipeptide (GO:0032495)2.62984888
63Arp2/3 complex-mediated actin nucleation (GO:0034314)2.62319327
64regulation of B cell differentiation (GO:0045577)2.62157826
65T cell migration (GO:0072678)2.60263297
66positive regulation of nuclease activity (GO:0032075)2.59823733
67regulation of interferon-alpha production (GO:0032647)2.58502431
68histone H3-K36 demethylation (GO:0070544)2.57799488
69lipopolysaccharide-mediated signaling pathway (GO:0031663)2.57429147
70regulation of T cell tolerance induction (GO:0002664)2.56450981
71activation of Rac GTPase activity (GO:0032863)2.55878919
72growth hormone receptor signaling pathway (GO:0060396)2.55668632
73modulation by virus of host process (GO:0019054)2.54907263
74tolerance induction (GO:0002507)2.54897829
75cortical actin cytoskeleton organization (GO:0030866)2.54113747
76positive regulation of lamellipodium organization (GO:1902745)2.53618503
77negative regulation of bone resorption (GO:0045779)2.49634280
78regulation of cholesterol homeostasis (GO:2000188)2.47511151
79negative regulation of toll-like receptor signaling pathway (GO:0034122)2.47279491
80epithelial cell differentiation involved in prostate gland development (GO:0060742)2.47212443
81NIK/NF-kappaB signaling (GO:0038061)2.46743198
82negative regulation of viral release from host cell (GO:1902187)2.46410221
83pinocytosis (GO:0006907)2.45156278
84response to type I interferon (GO:0034340)2.44524988
85detection of biotic stimulus (GO:0009595)2.43271707
86regulation of ARF GTPase activity (GO:0032312)2.42783335
87response to host (GO:0075136)2.42739735
88response to host defenses (GO:0052200)2.42739735
89response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.42739735
90B cell receptor signaling pathway (GO:0050853)2.42351745
91regulation of dendritic cell antigen processing and presentation (GO:0002604)2.42013796
92regulation of nuclease activity (GO:0032069)2.41928221
93regulation of early endosome to late endosome transport (GO:2000641)2.41664537
94negative regulation of granulocyte differentiation (GO:0030853)2.41246423
95negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.41123531
96negative regulation of stress fiber assembly (GO:0051497)2.40958192
97positive regulation of tolerance induction (GO:0002645)2.40421088
98negative regulation of leukocyte mediated immunity (GO:0002704)2.38925241
99low-density lipoprotein particle clearance (GO:0034383)2.38628713
100regulation of cholesterol storage (GO:0010885)2.38337826
101establishment of endothelial barrier (GO:0061028)2.38029451
102negative regulation of interleukin-12 production (GO:0032695)2.37999235
103regulation of mast cell activation involved in immune response (GO:0033006)2.36579758
104regulation of necrotic cell death (GO:0010939)2.36448833
105positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.36073652
106cellular extravasation (GO:0045123)2.35221244
107negative regulation of lymphocyte mediated immunity (GO:0002707)2.35082940
108intracellular estrogen receptor signaling pathway (GO:0030520)2.35001853
109endothelial tube morphogenesis (GO:0061154)2.33898565
110morphogenesis of an endothelium (GO:0003159)2.33898565
111endoplasmic reticulum unfolded protein response (GO:0030968)2.33524583
112detection of molecule of bacterial origin (GO:0032490)2.32649117
113macrophage activation involved in immune response (GO:0002281)2.32646474
114cellular response to type I interferon (GO:0071357)2.32350079
115type I interferon signaling pathway (GO:0060337)2.32350079
116regulation of regulated secretory pathway (GO:1903305)2.32121699
117response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.31541635
118response to host immune response (GO:0052572)2.31541635
119positive regulation of natural killer cell differentiation (GO:0032825)2.30330822
120regulation of defense response to virus by virus (GO:0050690)2.29875577
121positive regulation of Rap GTPase activity (GO:0032854)2.29747162
122regulation of T-helper 2 cell differentiation (GO:0045628)2.29112878
123cell-substrate adherens junction assembly (GO:0007045)2.29025153
124focal adhesion assembly (GO:0048041)2.29025153
125regulation of response to interferon-gamma (GO:0060330)2.28356000
126activation of JUN kinase activity (GO:0007257)2.28160882
127negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.26597021
128T cell costimulation (GO:0031295)2.26342235
129positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.24267322
130response to interleukin-15 (GO:0070672)2.24104225
131cellular response to unfolded protein (GO:0034620)2.24054918
132immunoglobulin mediated immune response (GO:0016064)2.21908829
133regulation of extracellular matrix disassembly (GO:0010715)2.21652660
134regulation of necroptotic process (GO:0060544)2.21524354
135cellular response to growth hormone stimulus (GO:0071378)2.21391604
136regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.20926263
137lymphocyte costimulation (GO:0031294)2.19133796
138negative regulation of fatty acid transport (GO:2000192)2.18533388
139positive regulation of p38MAPK cascade (GO:1900745)2.18484050
140regulation of erythrocyte differentiation (GO:0045646)2.16159068
141positive regulation of interferon-beta production (GO:0032728)2.15268047
142barbed-end actin filament capping (GO:0051016)2.15221874
143pentose-phosphate shunt (GO:0006098)2.14807863
144negative regulation of phagocytosis (GO:0050765)2.14091081
145apoptotic process involved in morphogenesis (GO:0060561)2.13231186
146regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.12443630
147regulation of natural killer cell mediated immunity (GO:0002715)2.12443630
148T cell apoptotic process (GO:0070231)2.12292156

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human3.40040401
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.31950213
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.13235851
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.03936494
5MYC_22102868_ChIP-Seq_BL_Human3.01226425
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.69569398
7VDR_21846776_ChIP-Seq_THP-1_Human2.67381302
8* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.45946319
9MYB_21317192_ChIP-Seq_ERMYB_Mouse2.27549354
10TCF7_22412390_ChIP-Seq_EML_Mouse2.22353253
11MAF_26560356_Chip-Seq_TH1_Human2.20257248
12STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.19847480
13SCL_19346495_ChIP-Seq_HPC-7_Human2.19826493
14NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.18076188
15IRF8_21731497_ChIP-ChIP_J774_Mouse2.12820207
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.08716880
17IRF8_27001747_Chip-Seq_BMDM_Mouse2.06070773
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.01371536
19* MYB_26560356_Chip-Seq_TH2_Human1.97068226
20UTX_26944678_Chip-Seq_JUKART_Human1.96888417
21ELK3_25401928_ChIP-Seq_HUVEC_Human1.94984716
22RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.94011321
23* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.93773585
24RUNX_20019798_ChIP-Seq_JUKART_Human1.88808168
25VDR_24763502_ChIP-Seq_THP-1_Human1.88632143
26KDM2B_26808549_Chip-Seq_DND41_Human1.86124051
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.84250878
28KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.83921688
29E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.82033233
30* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.81410519
31MYB_26560356_Chip-Seq_TH1_Human1.80543903
32STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.80146056
33TP63_17297297_ChIP-ChIP_HaCaT_Human1.79691689
34KDM2B_26808549_Chip-Seq_SUP-B15_Human1.74815644
35IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.74381242
36SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.73656605
37SPI1_23127762_ChIP-Seq_K562_Human1.73222311
38IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.71584972
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.68777971
40EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.68612555
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.63161572
42KDM2B_26808549_Chip-Seq_K562_Human1.61915005
43STAT4_19710469_ChIP-ChIP_TH1__Mouse1.59422567
44CLOCK_20551151_ChIP-Seq_293T_Human1.53989239
45KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.53936696
46TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52582748
47RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.52450666
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.52309786
49* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.50589474
50* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.50077563
51* SPI1_23547873_ChIP-Seq_NB4_Human1.49135590
52CTCF_27219007_Chip-Seq_ERYTHROID_Human1.45277526
53P68_20966046_ChIP-Seq_HELA_Human1.45030053
54FOXM1_23109430_ChIP-Seq_U2OS_Human1.44024451
55LXR_22292898_ChIP-Seq_THP-1_Human1.43405520
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.41641764
57PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.41534524
58GATA1_22025678_ChIP-Seq_K562_Human1.38850894
59TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.38500717
60GATA1_22383799_ChIP-Seq_G1ME_Mouse1.38459214
61THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.36213854
62SA1_27219007_Chip-Seq_ERYTHROID_Human1.35447778
63E2F7_22180533_ChIP-Seq_HELA_Human1.35264993
64BP1_19119308_ChIP-ChIP_Hs578T_Human1.34953711
65GATA1_19941826_ChIP-Seq_K562_Human1.34953117
66MAF_26560356_Chip-Seq_TH2_Human1.32607298
67RACK7_27058665_Chip-Seq_MCF-7_Human1.32192789
68NCOR1_26117541_ChIP-Seq_K562_Human1.30242091
69PPARA_22158963_ChIP-Seq_LIVER_Mouse1.29787214
70GATA3_27048872_Chip-Seq_THYMUS_Human1.29743272
71RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.29153942
72SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.28571347
73* GATA1_19941827_ChIP-Seq_MEL_Mouse1.28531076
74* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.27683349
75MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.27535522
76SMC4_20622854_ChIP-Seq_HELA_Human1.27489297
77BCOR_27268052_Chip-Seq_Bcells_Human1.24866787
78RUNX1_27514584_Chip-Seq_MCF-7_Human1.23341061
79GATA2_22383799_ChIP-Seq_G1ME_Mouse1.23198705
80PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.22340550
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21333966
82KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.21240919
83UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21162613
84CREB1_26743006_Chip-Seq_LNCaP_Human1.20544447
85SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.19132095
86TET1_21451524_ChIP-Seq_MESCs_Mouse1.18457506
87VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16639362
88ELF1_20517297_ChIP-Seq_JURKAT_Human1.15680972
89FOXO3_23340844_ChIP-Seq_DLD1_Human1.15542265
90ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.12767229
91Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.12292640
92ZFP281_18757296_ChIP-ChIP_E14_Mouse1.12281445
93CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.12138137
94PU_27001747_Chip-Seq_BMDM_Mouse1.11455264
95TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11228974
96ZNF263_19887448_ChIP-Seq_K562_Human1.10913320
97BCL6_27268052_Chip-Seq_Bcells_Human1.10863052
98EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.10219014
99ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10200675
100GATA2_19941826_ChIP-Seq_K562_Human1.10005811
101* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.09706566
102NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.08112035
103CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08002945
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07284592
105GATA2_21666600_ChIP-Seq_HMVEC_Human1.06651196
106KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.05692846
107KDM2B_26808549_Chip-Seq_JURKAT_Human1.05680527
108ATF3_27146783_Chip-Seq_COLON_Human1.05020832
109SOX2_27498859_Chip-Seq_STOMACH_Mouse1.04865619
110PU.1_20513432_ChIP-Seq_Bcells_Mouse1.04704574
111FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.03698871
112P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03427845
113DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03032697
114SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00878442
115PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00560222
116ESR2_21235772_ChIP-Seq_MCF-7_Human1.00378155
117CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99409559
118PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98363677
119CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.98299547
120RXR_22158963_ChIP-Seq_LIVER_Mouse0.97465964
121* GATA6_25053715_ChIP-Seq_YYC3_Human0.96831516
122STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96678780
123* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96594970
124LXR_22158963_ChIP-Seq_LIVER_Mouse0.95909503
125SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.95696612
126STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95513235
127GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95389895
128TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94505839
129SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.93497111

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003300_gastrointestinal_ulcer3.21643694
2MP0005451_abnormal_body_composition2.94353702
3MP0003705_abnormal_hypodermis_morpholog2.67416778
4MP0000685_abnormal_immune_system2.43402775
5MP0003303_peritoneal_inflammation2.36439042
6MP0005058_abnormal_lysosome_morphology2.17545455
7MP0010352_gastrointestinal_tract_polyps2.12566897
8MP0001835_abnormal_antigen_presentation2.11700644
9MP0009278_abnormal_bone_marrow2.05987474
10MP0002166_altered_tumor_susceptibility2.05282773
11MP0003436_decreased_susceptibility_to2.02892728
12MP0008260_abnormal_autophagy2.01234114
13MP0003566_abnormal_cell_adhesion1.99700733
14MP0003763_abnormal_thymus_physiology1.92965180
15MP0005387_immune_system_phenotype1.91629304
16MP0001790_abnormal_immune_system1.91629304
17MP0004947_skin_inflammation1.89278028
18MP0001800_abnormal_humoral_immune1.87092965
19MP0002396_abnormal_hematopoietic_system1.84598753
20MP0005464_abnormal_platelet_physiology1.84377879
21MP0009840_abnormal_foam_cell1.76681125
22MP0005671_abnormal_response_to1.76008344
23MP0002452_abnormal_antigen_presenting1.72841062
24MP0005000_abnormal_immune_tolerance1.71899934
25MP0002877_abnormal_melanocyte_morpholog1.70925758
26MP0002420_abnormal_adaptive_immunity1.68086045
27MP0001819_abnormal_immune_cell1.67147765
28MP0005025_abnormal_response_to1.66516884
29MP0002723_abnormal_immune_serum1.66120544
30MP0002419_abnormal_innate_immunity1.65974296
31MP0002398_abnormal_bone_marrow1.64361178
32MP0003183_abnormal_peptide_metabolism1.63104900
33MP0005076_abnormal_cell_differentiation1.61284402
34MP0005409_darkened_coat_color1.60463077
35MP0001873_stomach_inflammation1.60266861
36MP0002405_respiratory_system_inflammati1.59467112
37MP0010155_abnormal_intestine_physiology1.58448989
38MP0004808_abnormal_hematopoietic_stem1.56227317
39MP0005023_abnormal_wound_healing1.52660826
40MP0009785_altered_susceptibility_to1.50941222
41MP0003172_abnormal_lysosome_physiology1.50127221
42MP0006054_spinal_hemorrhage1.49766951
43MP0001545_abnormal_hematopoietic_system1.48690183
44MP0005397_hematopoietic_system_phenotyp1.48690183
45MP0006082_CNS_inflammation1.45428081
46MP0009333_abnormal_splenocyte_physiolog1.44538295
47MP0004185_abnormal_adipocyte_glucose1.43734087
48MP0003191_abnormal_cellular_cholesterol1.43701064
49MP0000716_abnormal_immune_system1.43039620
50MP0002722_abnormal_immune_system1.39588418
51MP0002006_tumorigenesis1.38356289
52MP0000689_abnormal_spleen_morphology1.36091057
53MP0004264_abnormal_extraembryonic_tissu1.36071432
54MP0004858_abnormal_nervous_system1.33922663
55MP0003866_abnormal_defecation1.33159304
56MP0001845_abnormal_inflammatory_respons1.32669326
57MP0000465_gastrointestinal_hemorrhage1.32546031
58MP0002429_abnormal_blood_cell1.28146872
59MP0000678_abnormal_parathyroid_gland1.26470905
60MP0002796_impaired_skin_barrier1.25231796
61MP0001533_abnormal_skeleton_physiology1.22785436
62MP0010307_abnormal_tumor_latency1.21625272
63MP0002148_abnormal_hypersensitivity_rea1.20107131
64MP0000703_abnormal_thymus_morphology1.19390797
65MP0004510_myositis1.19165030
66MP0003045_fibrosis1.17912351
67MP0003724_increased_susceptibility_to1.14102683
68MP0003091_abnormal_cell_migration1.14044564
69MP0000858_altered_metastatic_potential1.12995684
70MP0008438_abnormal_cutaneous_collagen1.09886657
71MP0004381_abnormal_hair_follicle1.09423165
72MP0002933_joint_inflammation1.08915977
73MP0008961_abnormal_basal_metabolism1.07598323
74MP0003453_abnormal_keratinocyte_physiol1.06773602
75MP0003448_altered_tumor_morphology1.06558170
76MP0003279_aneurysm1.06454462
77MP0000490_abnormal_crypts_of1.04893201
78MP0002009_preneoplasia1.02517063
79MP0005310_abnormal_salivary_gland1.02463843
80MP0002132_abnormal_respiratory_system1.01968649
81MP0005666_abnormal_adipose_tissue1.00003083
82MP0001348_abnormal_lacrimal_gland0.99589692
83MP0008469_abnormal_protein_level0.99432831
84MP0000609_abnormal_liver_physiology0.96561741
85MP0000733_abnormal_muscle_development0.93126390
86MP0003329_amyloid_beta_deposits0.92450663
87MP0003656_abnormal_erythrocyte_physiolo0.90795898
88MP0005360_urolithiasis0.90247371
89MP0000343_altered_response_to0.89708882
90MP0002998_abnormal_bone_remodeling0.88367343
91MP0005375_adipose_tissue_phenotype0.87665758
92MP0003828_pulmonary_edema0.87585749
93MP0004130_abnormal_muscle_cell0.87276112
94MP0001849_ear_inflammation0.87047246
95MP0009643_abnormal_urine_homeostasis0.86449940
96MP0002138_abnormal_hepatobiliary_system0.86197621
97MP0009931_abnormal_skin_appearance0.85764136
98MP0001853_heart_inflammation0.85723983
99MP0001663_abnormal_digestive_system0.85264407
100MP0005670_abnormal_white_adipose0.84395107
101MP0001958_emphysema0.84048691
102MP0001851_eye_inflammation0.84041651
103MP0010234_abnormal_vibrissa_follicle0.82949765
104MP0003075_altered_response_to0.82749310
105MP0005501_abnormal_skin_physiology0.82214849
106MP0005166_decreased_susceptibility_to0.81440156
107MP0005083_abnormal_biliary_tract0.78721882
108MP0000604_amyloidosis0.78605144
109MP0002019_abnormal_tumor_incidence0.78365913
110MP0002136_abnormal_kidney_physiology0.76570815
111MP0001216_abnormal_epidermal_layer0.76506834
112MP0000249_abnormal_blood_vessel0.76185282
113MP0000477_abnormal_intestine_morphology0.75016284
114MP0000598_abnormal_liver_morphology0.74628784
115MP0001915_intracranial_hemorrhage0.73968513
116MP0005390_skeleton_phenotype0.72902439
117MP0010630_abnormal_cardiac_muscle0.71885182
118MP0001243_abnormal_dermal_layer0.71510395
119MP0000003_abnormal_adipose_tissue0.70852020
120MP0000767_abnormal_smooth_muscle0.70383257
121MP0000371_diluted_coat_color0.69699717

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.56117432
2Abnormality of the nasal mucosa (HP:0000433)3.38323453
3Cerebral aneurysm (HP:0004944)3.37408105
4Nasal polyposis (HP:0100582)3.34170620
5Recurrent abscess formation (HP:0002722)3.29171767
6Pustule (HP:0200039)3.20186618
7Recurrent viral infections (HP:0004429)3.08232368
8Recurrent bacterial skin infections (HP:0005406)3.05972904
9Recurrent fungal infections (HP:0002841)3.04071565
10Polycythemia (HP:0001901)2.94733888
11Colitis (HP:0002583)2.89429552
12Dysostosis multiplex (HP:0000943)2.86612827
13Autoimmune thrombocytopenia (HP:0001973)2.83658959
14Inflammation of the large intestine (HP:0002037)2.83408168
15Spontaneous hematomas (HP:0007420)2.80719335
16Gastrointestinal inflammation (HP:0004386)2.80303120
17Elevated erythrocyte sedimentation rate (HP:0003565)2.78672938
18Hematochezia (HP:0002573)2.74234821
19Myositis (HP:0100614)2.72665556
20Broad face (HP:0000283)2.69966722
21T lymphocytopenia (HP:0005403)2.68835798
22Chronic otitis media (HP:0000389)2.67100997
23Urinary glycosaminoglycan excretion (HP:0003541)2.58670173
24Mucopolysacchariduria (HP:0008155)2.58670173
25Distal lower limb amyotrophy (HP:0008944)2.57850559
26Aortic aneurysm (HP:0004942)2.57844203
27Recurrent bronchitis (HP:0002837)2.54752917
28Abnormality of the fingertips (HP:0001211)2.54619406
29Abnormality of T cell number (HP:0011839)2.54246166
30Cellulitis (HP:0100658)2.53218347
31Interstitial pulmonary disease (HP:0006530)2.47115069
32Abnormality of polysaccharide metabolism (HP:0011012)2.44787876
33Abnormality of glycosaminoglycan metabolism (HP:0004371)2.44787876
34Abnormality of mucopolysaccharide metabolism (HP:0011020)2.44787876
35Fatigue (HP:0012378)2.44042792
36Obstructive sleep apnea (HP:0002870)2.42945607
37Flat acetabular roof (HP:0003180)2.42791633
38Increased connective tissue (HP:0009025)2.41541916
39Increased cerebral lipofuscin (HP:0011813)2.41102428
40IgM deficiency (HP:0002850)2.39957736
41Increased IgE level (HP:0003212)2.37039687
42Abnormal delayed hypersensitivity skin test (HP:0002963)2.35275259
43Vacuolated lymphocytes (HP:0001922)2.34854943
44Gastrointestinal infarctions (HP:0005244)2.32745871
45Thrombocytosis (HP:0001894)2.31592934
46Malnutrition (HP:0004395)2.31132966
47Obstructive lung disease (HP:0006536)2.30527012
48Chronic obstructive pulmonary disease (HP:0006510)2.30527012
49Orchitis (HP:0100796)2.21549005
50Recurrent skin infections (HP:0001581)2.20863178
51Abnormality of T cells (HP:0002843)2.19703841
52Aneurysm (HP:0002617)2.18293574
53Arterial thrombosis (HP:0004420)2.16420943
54Meningitis (HP:0001287)2.12615478
55Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.08726286
56Increased neuronal autofluorescent lipopigment (HP:0002074)2.02747668
57Thin bony cortex (HP:0002753)2.00678641
58Petechiae (HP:0000967)2.00603800
59Systemic lupus erythematosus (HP:0002725)2.00051188
60Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.99564311
61Chest pain (HP:0100749)1.98750309
62Osteolytic defects of the hand bones (HP:0009699)1.98239901
63Osteolytic defects of the phalanges of the hand (HP:0009771)1.98239901
64Emphysema (HP:0002097)1.98217623
65Distal lower limb muscle weakness (HP:0009053)1.97360436
66Frequent falls (HP:0002359)1.94794910
67Abnormal platelet function (HP:0011869)1.94743650
68Impaired platelet aggregation (HP:0003540)1.94743650
69Esophageal varix (HP:0002040)1.94727168
70Abnormality of glycolipid metabolism (HP:0010969)1.94197869
71Abnormality of liposaccharide metabolism (HP:0010968)1.94197869
72Abnormality of glycosphingolipid metabolism (HP:0004343)1.94197869
73Abnormality of macrophages (HP:0004311)1.94150147
74Gingival bleeding (HP:0000225)1.93468298
75Metaphyseal cupping (HP:0003021)1.92665466
76Reticulocytosis (HP:0001923)1.92440082
77Periodontitis (HP:0000704)1.92046628
78Recurrent cutaneous fungal infections (HP:0011370)1.91361502
79Chronic mucocutaneous candidiasis (HP:0002728)1.91361502
80Slow saccadic eye movements (HP:0000514)1.91108256
81Epistaxis (HP:0000421)1.90959137
82Aortic dissection (HP:0002647)1.90816940
83Abnormality of T cell physiology (HP:0011840)1.90697676
84Hand muscle atrophy (HP:0009130)1.90404948
85Recurrent gram-negative bacterial infections (HP:0005420)1.90268060
86Leukocytosis (HP:0001974)1.89529779
87Gastrointestinal stroma tumor (HP:0100723)1.89406505
88Increased density of long bones (HP:0006392)1.88843207
89Ulnar bowing (HP:0003031)1.88528338
90Eosinophilia (HP:0001880)1.88332825
91Increased serum ferritin (HP:0003281)1.87638284
92Abnormality of the thoracic spine (HP:0100711)1.87537713
93Upper limb amyotrophy (HP:0009129)1.87089308
94Distal upper limb amyotrophy (HP:0007149)1.87089308
95Papilloma (HP:0012740)1.86006127
96Verrucae (HP:0200043)1.86006127
97Dysmetric saccades (HP:0000641)1.85460109
98Myocardial infarction (HP:0001658)1.84883881
99Abnormal platelet volume (HP:0011876)1.84637194
100Panhypogammaglobulinemia (HP:0003139)1.84307661
101Osteomyelitis (HP:0002754)1.84049658
102Polygenic inheritance (HP:0010982)1.83003448
103Hypertriglyceridemia (HP:0002155)1.81395940
104Hypertensive crisis (HP:0100735)1.80323840
105Chronic diarrhea (HP:0002028)1.80003287
106J-shaped sella turcica (HP:0002680)1.79157864
107Spondylolisthesis (HP:0003302)1.79044086
108Peritonitis (HP:0002586)1.78927032
109Protrusio acetabuli (HP:0003179)1.77013234
110Vasculitis (HP:0002633)1.76369693
111Vertebral compression fractures (HP:0002953)1.76276106
112Prolonged bleeding time (HP:0003010)1.75877178
113Urticaria (HP:0001025)1.75869312
114Loss of speech (HP:0002371)1.75661960
115Asymmetric septal hypertrophy (HP:0001670)1.75270080
116Dilatation of the ascending aorta (HP:0005111)1.74101507
117Disproportionate tall stature (HP:0001519)1.73803119
118Gingivitis (HP:0000230)1.72358402
119Ankyloglossia (HP:0010296)1.71194738
120Thoracic kyphosis (HP:0002942)1.71013505
121Mitral valve prolapse (HP:0001634)1.70865742
122Gastrointestinal dysmotility (HP:0002579)1.70256594
123Abnormality of the distal phalanx of the thumb (HP:0009617)1.69728993
124Hypoglycemic coma (HP:0001325)1.69678130
125Bicuspid aortic valve (HP:0001647)1.69358253
126Nonimmune hydrops fetalis (HP:0001790)1.68354220
127Retrobulbar optic neuritis (HP:0100654)1.67895576
128Optic neuritis (HP:0100653)1.67895576
129Cervical subluxation (HP:0003308)1.67638258
130IgA deficiency (HP:0002720)1.67382392
131Mediastinal lymphadenopathy (HP:0100721)1.66475327
132Increased mean platelet volume (HP:0011877)1.65997270
133Viral hepatitis (HP:0006562)1.64738001
134Cholecystitis (HP:0001082)1.63791738
135Abnormal gallbladder physiology (HP:0012438)1.63791738
136Achilles tendon contracture (HP:0001771)1.63488545
137Hyperacusis (HP:0010780)1.62652997
138Abnormality of oral frenula (HP:0000190)1.61586817
139Bone pain (HP:0002653)1.61479892
140Persistence of primary teeth (HP:0006335)1.59439555
141Seborrheic dermatitis (HP:0001051)1.58813253
142Long palpebral fissure (HP:0000637)1.58039684
143Abdominal distention (HP:0003270)1.56556944

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.87336139
2PRPF4B3.42057763
3MAP4K13.21125281
4ERN13.17951179
5PKN22.99581711
6SMG12.94138069
7EEF2K2.62472562
8RIPK42.61166960
9STK102.49062667
10EPHB12.44482320
11MAP3K102.31759449
12LRRK22.14177879
13TGFBR21.99344551
14TYK21.94057872
15TBK11.91610951
16JAK31.87592697
17PTK61.86295665
18CDK121.84909356
19TTN1.81136270
20ZAP701.66654977
21MAP3K131.65870688
22FGFR41.59479078
23MST1R1.49160969
24RIPK11.43886798
25CAMK1D1.41120139
26SIK11.40406865
27JAK11.38188850
28ITK1.37452300
29CSK1.36481867
30CDC42BPA1.32700111
31EPHA21.28563761
32KSR21.24813323
33MAP2K31.24795565
34GRK61.24261044
35BTK1.23906622
36CSF1R1.22348782
37MARK21.21739728
38MAP3K11.19598001
39TAOK21.19155000
40IKBKE1.16508582
41TAOK31.16150351
42ICK1.15489935
43KDR1.14847019
44DMPK1.10752059
45TNK21.08775799
46FLT31.07716563
47PAK41.06322991
48TXK1.06259110
49KIT1.02273956
50PDPK11.01712025
51CAMK1G1.01624821
52PRKD20.97023201
53BLK0.97015553
54TESK10.96438431
55FES0.95102424
56MARK30.94038056
57HCK0.93392518
58SIK30.89655178
59SCYL20.89418474
60MAP3K60.87928438
61RPS6KA40.87816737
62LCK0.86855247
63TAOK10.85694877
64MAP3K140.85627278
65MAPK110.85519888
66FGFR30.83161857
67MTOR0.82367565
68IKBKB0.81930786
69NLK0.81526479
70PTK20.81086403
71JAK20.80661766
72IRAK30.79158085
73IRAK40.78996974
74RPS6KA20.78360574
75TRPM70.76963532
76PIM10.76104116
77NEK90.75770238
78RPS6KL10.75439364
79RPS6KC10.75439364
80MAP2K20.75165331
81PDGFRA0.74013743
82CDK60.73696253
83CHUK0.73169877
84NEK20.72524561
85BMX0.70205717
86PDGFRB0.70158651
87STK30.69357551
88MAP3K80.69233298
89MST40.68613211
90STK40.67519183
91MAPK150.67104636
92CDK40.66978399
93NME20.66776829
94MAPK120.65909384
95CLK10.65123356
96LMTK20.64370021
97EPHA30.63136868
98MAP3K20.62166664
99SYK0.61446623
100TEC0.60164901
101RPS6KA60.58461059
102DYRK1B0.57904378
103MAP3K70.57844264
104IRAK20.57115340
105HIPK20.56992169
106FGR0.54776973
107TESK20.54498236
108PASK0.53835599
109MAPKAPK30.50789105
110MAP3K30.50769339
111RPS6KB20.50282858
112ILK0.49628620
113PRKG20.48180526
114MET0.47615424
115PRKCH0.47352110
116MAPK70.46751773
117RET0.46247408
118SGK30.45371983
119IRAK10.44483232
120PAK20.44456237
121MAP2K60.44186141
122MAPKAPK20.43946351
123TGFBR10.43589266
124CDK90.43206853
125MATK0.42592521
126LYN0.41426849
127PDK10.41111962
128PRKD10.40181528
129EGFR0.39481815
130STK380.38824486
131SIK20.38758615
132MAP3K110.38236808
133PRKCQ0.38195666
134BRD40.37922316
135TYRO30.37831401
136CAMKK10.37646633
137MELK0.37524298

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.66388025
2B cell receptor signaling pathway_Homo sapiens_hsa046622.06562599
3Osteoclast differentiation_Homo sapiens_hsa043802.05666555
4Primary immunodeficiency_Homo sapiens_hsa053402.04657562
5Leishmaniasis_Homo sapiens_hsa051402.02107767
6Antigen processing and presentation_Homo sapiens_hsa046121.88940152
7Leukocyte transendothelial migration_Homo sapiens_hsa046701.73840457
8* Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.73683901
9Measles_Homo sapiens_hsa051621.70126929
10NF-kappa B signaling pathway_Homo sapiens_hsa040641.68072853
11Toxoplasmosis_Homo sapiens_hsa051451.67017528
12Chronic myeloid leukemia_Homo sapiens_hsa052201.66263482
13Acute myeloid leukemia_Homo sapiens_hsa052211.61466180
14* Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.55239175
15Glycosaminoglycan degradation_Homo sapiens_hsa005311.50550344
16Toll-like receptor signaling pathway_Homo sapiens_hsa046201.48738909
17T cell receptor signaling pathway_Homo sapiens_hsa046601.46331901
18Other glycan degradation_Homo sapiens_hsa005111.41257069
19Lysosome_Homo sapiens_hsa041421.40859237
20Pancreatic cancer_Homo sapiens_hsa052121.38820175
21Cyanoamino acid metabolism_Homo sapiens_hsa004601.37801548
22Caffeine metabolism_Homo sapiens_hsa002321.34414917
23Jak-STAT signaling pathway_Homo sapiens_hsa046301.32741232
24Shigellosis_Homo sapiens_hsa051311.29479213
25Viral myocarditis_Homo sapiens_hsa054161.29187507
26Staphylococcus aureus infection_Homo sapiens_hsa051501.27641469
27Influenza A_Homo sapiens_hsa051641.27469987
28Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.23478118
29Legionellosis_Homo sapiens_hsa051341.23346316
30Hematopoietic cell lineage_Homo sapiens_hsa046401.23092797
31Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.21820573
32Apoptosis_Homo sapiens_hsa042101.21486851
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.21304958
34Fructose and mannose metabolism_Homo sapiens_hsa000511.20950712
35Small cell lung cancer_Homo sapiens_hsa052221.20473481
36Insulin resistance_Homo sapiens_hsa049311.18922315
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.16868358
38Herpes simplex infection_Homo sapiens_hsa051681.16747142
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.15955953
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.15624045
41Platelet activation_Homo sapiens_hsa046111.13199474
42TNF signaling pathway_Homo sapiens_hsa046681.12067920
43Intestinal immune network for IgA production_Homo sapiens_hsa046721.11202627
44Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.10995265
45Allograft rejection_Homo sapiens_hsa053301.09279851
46Graft-versus-host disease_Homo sapiens_hsa053321.08878131
47Hepatitis B_Homo sapiens_hsa051611.08270499
48Malaria_Homo sapiens_hsa051441.07467177
49Tuberculosis_Homo sapiens_hsa051521.06178304
50NOD-like receptor signaling pathway_Homo sapiens_hsa046211.05735128
51Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.03348561
52Pertussis_Homo sapiens_hsa051331.03204673
53Autoimmune thyroid disease_Homo sapiens_hsa053201.00625875
54Adherens junction_Homo sapiens_hsa045201.00239916
55Thyroid cancer_Homo sapiens_hsa052160.99788110
56Adipocytokine signaling pathway_Homo sapiens_hsa049200.99264743
57Chemokine signaling pathway_Homo sapiens_hsa040620.98554657
58GnRH signaling pathway_Homo sapiens_hsa049120.98521745
59Choline metabolism in cancer_Homo sapiens_hsa052310.97140261
60RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.96091960
61Phosphatidylinositol signaling system_Homo sapiens_hsa040700.95591479
62Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.95519213
63VEGF signaling pathway_Homo sapiens_hsa043700.95125404
64Viral carcinogenesis_Homo sapiens_hsa052030.94728483
65Notch signaling pathway_Homo sapiens_hsa043300.93469849
66Hepatitis C_Homo sapiens_hsa051600.93368763
67Focal adhesion_Homo sapiens_hsa045100.92871173
68Lysine degradation_Homo sapiens_hsa003100.91554213
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.90970939
70ErbB signaling pathway_Homo sapiens_hsa040120.88375255
71Inositol phosphate metabolism_Homo sapiens_hsa005620.87543555
72* Phospholipase D signaling pathway_Homo sapiens_hsa040720.86310582
73Salmonella infection_Homo sapiens_hsa051320.85952333
74Proteoglycans in cancer_Homo sapiens_hsa052050.84520019
75Renal cell carcinoma_Homo sapiens_hsa052110.83471704
76Non-small cell lung cancer_Homo sapiens_hsa052230.82617441
77Transcriptional misregulation in cancer_Homo sapiens_hsa052020.81847578
78Prion diseases_Homo sapiens_hsa050200.81214671
79Galactose metabolism_Homo sapiens_hsa000520.80783905
80Prolactin signaling pathway_Homo sapiens_hsa049170.79934548
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79244043
82* Endocytosis_Homo sapiens_hsa041440.78177448
83Glioma_Homo sapiens_hsa052140.78155493
84HTLV-I infection_Homo sapiens_hsa051660.77667700
85mTOR signaling pathway_Homo sapiens_hsa041500.77387035
86ABC transporters_Homo sapiens_hsa020100.75789921
87Colorectal cancer_Homo sapiens_hsa052100.74815898
88Regulation of actin cytoskeleton_Homo sapiens_hsa048100.73914204
89Amoebiasis_Homo sapiens_hsa051460.72690669
90Estrogen signaling pathway_Homo sapiens_hsa049150.72138303
91Sphingolipid signaling pathway_Homo sapiens_hsa040710.72055096
92Pentose phosphate pathway_Homo sapiens_hsa000300.69836939
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66798459
94HIF-1 signaling pathway_Homo sapiens_hsa040660.64931031
95Dorso-ventral axis formation_Homo sapiens_hsa043200.64893643
96MicroRNAs in cancer_Homo sapiens_hsa052060.62169117
97African trypanosomiasis_Homo sapiens_hsa051430.61166131
98Prostate cancer_Homo sapiens_hsa052150.60768694
99Endometrial cancer_Homo sapiens_hsa052130.59470146
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59194945
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.55791464
102Selenocompound metabolism_Homo sapiens_hsa004500.55730945
103Renin-angiotensin system_Homo sapiens_hsa046140.54364898
104Epstein-Barr virus infection_Homo sapiens_hsa051690.54141712
105Phagosome_Homo sapiens_hsa041450.53987823
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53980785
107Bladder cancer_Homo sapiens_hsa052190.53108771
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.52813365
109Maturity onset diabetes of the young_Homo sapiens_hsa049500.51816424
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51247687
111AMPK signaling pathway_Homo sapiens_hsa041520.50280309
112FoxO signaling pathway_Homo sapiens_hsa040680.49091721
113Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48935789
114p53 signaling pathway_Homo sapiens_hsa041150.47135212
115Type II diabetes mellitus_Homo sapiens_hsa049300.45785124
116Fat digestion and absorption_Homo sapiens_hsa049750.44233664
117Pathways in cancer_Homo sapiens_hsa052000.43355584
118Insulin signaling pathway_Homo sapiens_hsa049100.43271490
119ECM-receptor interaction_Homo sapiens_hsa045120.42817150
120Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.42607662

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