DOPEY1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1interkinetic nuclear migration (GO:0022027)4.80483964
2regulation of acrosome reaction (GO:0060046)4.65890385
3oocyte development (GO:0048599)3.99292843
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.89801205
5regulation of short-term neuronal synaptic plasticity (GO:0048172)3.85530566
6nucleus localization (GO:0051647)3.77323955
7locomotory exploration behavior (GO:0035641)3.75403843
8vocalization behavior (GO:0071625)3.69750755
9cerebellar Purkinje cell differentiation (GO:0021702)3.64535888
10ionotropic glutamate receptor signaling pathway (GO:0035235)3.62852285
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.59635166
12retinal cone cell development (GO:0046549)3.58579427
13regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.58100632
14piRNA metabolic process (GO:0034587)3.55569785
15embryonic retina morphogenesis in camera-type eye (GO:0060059)3.55316492
16regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.54502742
17presynaptic membrane assembly (GO:0097105)3.52665278
18regulation of female gonad development (GO:2000194)3.48975460
19glutamate receptor signaling pathway (GO:0007215)3.43420359
20neuron cell-cell adhesion (GO:0007158)3.41303888
21membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.35920020
22regulation of glutamate receptor signaling pathway (GO:1900449)3.32191014
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.28396911
24G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.17245058
25startle response (GO:0001964)3.16778645
26cellular potassium ion homeostasis (GO:0030007)3.13840771
27cilium or flagellum-dependent cell motility (GO:0001539)3.13218322
28presynaptic membrane organization (GO:0097090)3.11971189
29gamma-aminobutyric acid transport (GO:0015812)3.09328947
30synaptic transmission, glutamatergic (GO:0035249)3.08764369
31response to pheromone (GO:0019236)3.08262205
32synaptic vesicle maturation (GO:0016188)3.05212311
33regulation of calcium ion-dependent exocytosis (GO:0017158)3.03966812
34L-amino acid import (GO:0043092)3.02254109
35gamma-aminobutyric acid signaling pathway (GO:0007214)2.99402507
36protein targeting to Golgi (GO:0000042)2.99348395
37DNA methylation involved in gamete generation (GO:0043046)2.99251490
38neuron-neuron synaptic transmission (GO:0007270)2.97633069
39regulation of sarcomere organization (GO:0060297)2.96703553
40phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.96524014
41pyrimidine nucleobase catabolic process (GO:0006208)2.96139553
42neurotransmitter-gated ion channel clustering (GO:0072578)2.93249109
43central nervous system neuron axonogenesis (GO:0021955)2.91949532
44histone H3-K4 trimethylation (GO:0080182)2.89138408
45synaptic vesicle exocytosis (GO:0016079)2.88862585
46long-term memory (GO:0007616)2.87611341
47membrane depolarization during action potential (GO:0086010)2.87512153
48regulation of synaptic vesicle exocytosis (GO:2000300)2.87249116
49regulation of synaptic transmission, glutamatergic (GO:0051966)2.87026483
50protein localization to synapse (GO:0035418)2.86587935
51negative regulation of synaptic transmission, GABAergic (GO:0032229)2.86207692
52epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.85430852
53retrograde transport, vesicle recycling within Golgi (GO:0000301)2.84718592
54negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.83889407
55establishment of protein localization to Golgi (GO:0072600)2.83597587
56glutamate secretion (GO:0014047)2.82967658
57phosphorelay signal transduction system (GO:0000160)2.79589607
58dendrite morphogenesis (GO:0048813)2.78272086
59regulation of excitatory postsynaptic membrane potential (GO:0060079)2.78155191
60transmission of nerve impulse (GO:0019226)2.76668016
61multicellular organism reproduction (GO:0032504)2.75847771
62synaptic vesicle docking involved in exocytosis (GO:0016081)2.75600478
63calcium ion import (GO:0070509)2.75194663
64regulation of postsynaptic membrane potential (GO:0060078)2.74019556
65axonal fasciculation (GO:0007413)2.72757551
66neural tube formation (GO:0001841)2.71746139
67neurotransmitter secretion (GO:0007269)2.71037372
68regulation of meiosis I (GO:0060631)2.67999153
69long-term synaptic potentiation (GO:0060291)2.67972827
70negative regulation of cytosolic calcium ion concentration (GO:0051481)2.67820496
71regulation of DNA methylation (GO:0044030)2.67540781
72dentate gyrus development (GO:0021542)2.66087625
73response to histamine (GO:0034776)2.63434922
74neuron recognition (GO:0008038)2.62873641
75histone H3-K9 demethylation (GO:0033169)2.62484789
76regulation of ARF protein signal transduction (GO:0032012)2.60859093
77sodium ion export (GO:0071436)2.60749453
78histone H3-K36 demethylation (GO:0070544)2.60112673
79regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.59896598
80positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.59278394
81neuronal action potential propagation (GO:0019227)2.59003030
82membrane hyperpolarization (GO:0060081)2.57816747
83exploration behavior (GO:0035640)2.57715826
84regulation of protein glycosylation (GO:0060049)2.57349665
85cilium movement (GO:0003341)2.57145651
86synaptic vesicle endocytosis (GO:0048488)2.56497103
87nucleobase catabolic process (GO:0046113)2.55960051
88auditory receptor cell differentiation (GO:0042491)2.55667616
89postsynaptic membrane organization (GO:0001941)2.55300344
90negative regulation of cell killing (GO:0031342)2.55037556
91negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.55037556
92response to auditory stimulus (GO:0010996)2.54985414
93tachykinin receptor signaling pathway (GO:0007217)2.54942670
94meiotic cell cycle (GO:0051321)2.53219290
95positive regulation of histone H3-K4 methylation (GO:0051571)2.53196732
96membrane depolarization (GO:0051899)2.52878223
97regulation of neurotransmitter secretion (GO:0046928)2.52640733
98regulation of synaptic vesicle transport (GO:1902803)2.51935030
99nerve growth factor signaling pathway (GO:0038180)2.51259645
100cerebellar granule cell differentiation (GO:0021707)2.51162510
101vesicle transport along microtubule (GO:0047496)2.49565878
102somite rostral/caudal axis specification (GO:0032525)2.47839704
103innervation (GO:0060384)2.47715624
104microtubule anchoring (GO:0034453)2.45284000
105cochlea development (GO:0090102)2.45170736
106positive regulation of CREB transcription factor activity (GO:0032793)2.44826382
107cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.43747241
108brain morphogenesis (GO:0048854)2.43734164
109detection of calcium ion (GO:0005513)2.43413209
110phospholipid dephosphorylation (GO:0046839)2.42514936
111early endosome to late endosome transport (GO:0045022)2.41289797
112* Golgi to endosome transport (GO:0006895)2.40554457
113gene silencing by RNA (GO:0031047)2.40020919
114cell differentiation in hindbrain (GO:0021533)2.39617847
115synapse assembly (GO:0007416)2.39588438
116phosphatidylinositol dephosphorylation (GO:0046856)2.39235353
117negative regulation of dendrite development (GO:2000171)2.38113419
118positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.38013915
119positive regulation of dendritic spine morphogenesis (GO:0061003)2.36903976
120positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.36175322
121proline transport (GO:0015824)2.34851763
122establishment of nucleus localization (GO:0040023)2.34181008
123adaptation of signaling pathway (GO:0023058)2.33902200
124cyclic nucleotide catabolic process (GO:0009214)2.33769006
125gastrulation with mouth forming second (GO:0001702)2.33500742
126protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.33490624
127regulation of dendritic spine morphogenesis (GO:0061001)2.32145315
128cytoplasmic mRNA processing body assembly (GO:0033962)2.32061672
129layer formation in cerebral cortex (GO:0021819)2.31944668
130neurotransmitter transport (GO:0006836)2.30789979
131negative regulation of neurotransmitter secretion (GO:0046929)2.30459806
132dendritic spine morphogenesis (GO:0060997)2.29433865
133epithelial cilium movement (GO:0003351)2.29239657
134positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.28957562
135positive regulation of membrane potential (GO:0045838)2.28843635
136potassium ion import (GO:0010107)2.28652236
137chemosensory behavior (GO:0007635)2.28070816
138central nervous system projection neuron axonogenesis (GO:0021952)2.27917875
139adult walking behavior (GO:0007628)2.26570479
140positive regulation of humoral immune response (GO:0002922)2.26495792
141regulation of beta-amyloid formation (GO:1902003)2.26445998
142cAMP catabolic process (GO:0006198)2.26400397
143striatum development (GO:0021756)2.25324703
144retinal rod cell development (GO:0046548)2.25034048
145regulation of neuronal synaptic plasticity (GO:0048168)2.24662827
146auditory behavior (GO:0031223)2.24598873
147glycosphingolipid biosynthetic process (GO:0006688)2.23896670
148olfactory bulb development (GO:0021772)2.23684586
149regulation of neurotransmitter transport (GO:0051588)2.23530421
150microtubule nucleation (GO:0007020)2.21660773
151regulation of dendritic spine development (GO:0060998)2.20543727
152regulation of voltage-gated calcium channel activity (GO:1901385)2.19945363
153cytoplasmic microtubule organization (GO:0031122)2.19473068
154cAMP-mediated signaling (GO:0019933)2.19278123
155organelle transport along microtubule (GO:0072384)2.18702690
156regulation of synapse structural plasticity (GO:0051823)2.18618291
157prepulse inhibition (GO:0060134)2.18526612
158regulation of Rac protein signal transduction (GO:0035020)2.17817703
159monoubiquitinated protein deubiquitination (GO:0035520)2.17378773

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.68095160
2GBX2_23144817_ChIP-Seq_PC3_Human3.63827492
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.82723394
4SMAD_19615063_ChIP-ChIP_OVARY_Human2.32447527
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.30659053
6* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.17840876
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.10564719
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08478139
9DROSHA_22980978_ChIP-Seq_HELA_Human2.05309806
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03877553
11CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.02033611
12AR_21572438_ChIP-Seq_LNCaP_Human1.97717518
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.96566492
14POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96178634
15TAF15_26573619_Chip-Seq_HEK293_Human1.92777688
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.92392316
17PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.86367525
18SMAD4_21799915_ChIP-Seq_A2780_Human1.86316721
19JARID2_20064375_ChIP-Seq_MESCs_Mouse1.85965247
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.74993710
21P300_19829295_ChIP-Seq_ESCs_Human1.71347293
22* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.69327831
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.69035790
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66761704
25PIAS1_25552417_ChIP-Seq_VCAP_Human1.66421108
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.64905581
27BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.64154358
28SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.62384378
29STAT3_23295773_ChIP-Seq_U87_Human1.61164754
30ZNF217_24962896_ChIP-Seq_MCF-7_Human1.60794058
31CDX2_19796622_ChIP-Seq_MESCs_Mouse1.60075165
32RNF2_18974828_ChIP-Seq_MESCs_Mouse1.59711040
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.59711040
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56424197
35SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.56204395
36REST_21632747_ChIP-Seq_MESCs_Mouse1.55248656
37IGF1R_20145208_ChIP-Seq_DFB_Human1.54158578
38TP53_16413492_ChIP-PET_HCT116_Human1.53567100
39EED_16625203_ChIP-ChIP_MESCs_Mouse1.52978399
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.50881994
41TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.50234527
42FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.49961477
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.49254068
44TCF4_23295773_ChIP-Seq_U87_Human1.49213859
45VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.46905450
46EZH2_27304074_Chip-Seq_ESCs_Mouse1.46752797
47TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45833105
48OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44473677
49ARNT_22903824_ChIP-Seq_MCF-7_Human1.44112170
50RNF2_27304074_Chip-Seq_ESCs_Mouse1.44083085
51VDR_22108803_ChIP-Seq_LS180_Human1.43751540
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.43216510
53JARID2_20075857_ChIP-Seq_MESCs_Mouse1.42071872
54AHR_22903824_ChIP-Seq_MCF-7_Human1.41968109
55AR_25329375_ChIP-Seq_VCAP_Human1.40873474
56EWS_26573619_Chip-Seq_HEK293_Human1.40010179
57CBP_20019798_ChIP-Seq_JUKART_Human1.37656759
58IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37656759
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37579037
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.36282700
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34999352
62FUS_26573619_Chip-Seq_HEK293_Human1.34650883
63RNF2_27304074_Chip-Seq_NSC_Mouse1.34471272
64* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32590560
65PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32225550
66SOX2_21211035_ChIP-Seq_LN229_Gbm1.31988678
67ER_23166858_ChIP-Seq_MCF-7_Human1.31405822
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.30578527
69TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30578527
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.29793251
71SUZ12_27294783_Chip-Seq_ESCs_Mouse1.29162195
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.25580044
73LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25173788
74E2F1_18555785_Chip-Seq_ESCs_Mouse1.24630836
75* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.23643918
76EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23643546
77BCAT_22108803_ChIP-Seq_LS180_Human1.23542211
78MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.23255333
79EP300_21415370_ChIP-Seq_HL-1_Mouse1.23181605
80STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.23132919
81SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21690790
82UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21341344
83NR3C1_21868756_ChIP-Seq_MCF10A_Human1.21203518
84RARB_27405468_Chip-Seq_BRAIN_Mouse1.20579923
85CMYC_18555785_Chip-Seq_ESCs_Mouse1.20128670
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18815428
87* AR_19668381_ChIP-Seq_PC3_Human1.17509381
88RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.16444535
89STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16312108
90SALL1_21062744_ChIP-ChIP_HESCs_Human1.16249177
91P53_22387025_ChIP-Seq_ESCs_Mouse1.16089276
92BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15855942
93ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.15579500
94FLI1_21867929_ChIP-Seq_TH2_Mouse1.15138418
95CTNNB1_20460455_ChIP-Seq_HCT116_Human1.12345305
96FOXM1_26456572_ChIP-Seq_MCF-7_Human1.12102319
97YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11988669
98RUNX2_22187159_ChIP-Seq_PCA_Human1.11899801
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.11055359
100SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10922605
101NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10357107
102TP53_18474530_ChIP-ChIP_U2OS_Human1.10345828
103TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.10109522
104TCF4_22108803_ChIP-Seq_LS180_Human1.09875595
105PRDM14_20953172_ChIP-Seq_ESCs_Human1.09181527
106SMAD3_21741376_ChIP-Seq_HESCs_Human1.07247072
107PCGF2_27294783_Chip-Seq_NPCs_Mouse1.07060523
108ZNF274_21170338_ChIP-Seq_K562_Hela1.06361108
109CBX2_27304074_Chip-Seq_ESCs_Mouse1.06106378
110PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06009523
111NFE2_27457419_Chip-Seq_LIVER_Mouse1.05163046
112WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04650604
113EZH2_27294783_Chip-Seq_NPCs_Mouse1.03583348
114TAL1_26923725_Chip-Seq_HPCs_Mouse1.02381493
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02228006
116CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01969343
117MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01687425
118P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01431197
119KDM2B_26808549_Chip-Seq_REH_Human1.01078366
120TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01067835
121P300_18555785_Chip-Seq_ESCs_Mouse1.00845488
122RXR_22108803_ChIP-Seq_LS180_Human1.00777235
123RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.00716907
124SMAD4_21741376_ChIP-Seq_EPCs_Human0.98999097

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.44188756
2MP0000569_abnormal_digit_pigmentation3.80902807
3MP0003880_abnormal_central_pattern3.28159318
4MP0003635_abnormal_synaptic_transmissio3.21646007
5MP0003890_abnormal_embryonic-extraembry3.17040908
6MP0003787_abnormal_imprinting3.11285801
7MP0009046_muscle_twitch3.02084057
8MP0005423_abnormal_somatic_nervous2.91755701
9MP0009745_abnormal_behavioral_response2.84093046
10MP0001486_abnormal_startle_reflex2.81857528
11MP0004270_analgesia2.72281292
12MP0005551_abnormal_eye_electrophysiolog2.65246555
13MP0002063_abnormal_learning/memory/cond2.64553492
14MP0002064_seizures2.59081661
15MP0008057_abnormal_DNA_replication2.46149857
16MP0002572_abnormal_emotion/affect_behav2.45532332
17MP0002272_abnormal_nervous_system2.31284103
18MP0001501_abnormal_sleep_pattern2.26868323
19MP0001968_abnormal_touch/_nociception2.19699552
20MP0003718_maternal_effect2.19611429
21MP0009780_abnormal_chondrocyte_physiolo2.18021473
22MP0002734_abnormal_mechanical_nocicepti2.09512634
23MP0005646_abnormal_pituitary_gland2.06521577
24MP0002067_abnormal_sensory_capabilities2.04708276
25MP0003045_fibrosis2.04043599
26MP0008569_lethality_at_weaning1.91530165
27MP0001440_abnormal_grooming_behavior1.86605415
28MP0002735_abnormal_chemical_nociception1.81707785
29MP0000778_abnormal_nervous_system1.76944950
30MP0005645_abnormal_hypothalamus_physiol1.74478717
31MP0001984_abnormal_olfaction1.66615617
32MP0002736_abnormal_nociception_after1.64608084
33MP0002837_dystrophic_cardiac_calcinosis1.63487667
34MP0002557_abnormal_social/conspecific_i1.58497316
35MP0010234_abnormal_vibrissa_follicle1.58114704
36MP0006072_abnormal_retinal_apoptosis1.57825952
37MP0000383_abnormal_hair_follicle1.56398198
38MP0004924_abnormal_behavior1.55969689
39MP0005386_behavior/neurological_phenoty1.55969689
40MP0004742_abnormal_vestibular_system1.53864203
41MP0001502_abnormal_circadian_rhythm1.53774780
42MP0003879_abnormal_hair_cell1.53373839
43MP0002184_abnormal_innervation1.52443086
44MP0005253_abnormal_eye_physiology1.51027589
45MP0001188_hyperpigmentation1.50348088
46MP0001986_abnormal_taste_sensitivity1.49211814
47MP0003183_abnormal_peptide_metabolism1.48643554
48MP0002009_preneoplasia1.47979981
49MP0003690_abnormal_glial_cell1.46856622
50MP0003123_paternal_imprinting1.44762982
51MP0003633_abnormal_nervous_system1.44013781
52MP0005395_other_phenotype1.40595313
53MP0002229_neurodegeneration1.34565835
54MP0001970_abnormal_pain_threshold1.32888855
55MP0006292_abnormal_olfactory_placode1.29756586
56MP0002882_abnormal_neuron_morphology1.28374791
57MP0004043_abnormal_pH_regulation1.27642687
58MP0001299_abnormal_eye_distance/1.22783156
59MP0003631_nervous_system_phenotype1.21701232
60MP0000955_abnormal_spinal_cord1.18492744
61MP0002733_abnormal_thermal_nociception1.18439952
62MP0008877_abnormal_DNA_methylation1.18027964
63MP0005394_taste/olfaction_phenotype1.16073966
64MP0005499_abnormal_olfactory_system1.16073966
65MP0004142_abnormal_muscle_tone1.15709757
66MP0002909_abnormal_adrenal_gland1.14644312
67MP0002751_abnormal_autonomic_nervous1.14538874
68MP0002876_abnormal_thyroid_physiology1.14442270
69MP0001177_atelectasis1.14100453
70MP0010386_abnormal_urinary_bladder1.12156969
71MP0006276_abnormal_autonomic_nervous1.10827782
72MP0004811_abnormal_neuron_physiology1.09953984
73MP0002090_abnormal_vision1.08461409
74MP0002066_abnormal_motor_capabilities/c1.07883748
75MP0003950_abnormal_plasma_membrane1.06649190
76MP0002234_abnormal_pharynx_morphology1.04882935
77MP0002822_catalepsy1.04241369
78MP0004885_abnormal_endolymph1.02370002
79MP0003632_abnormal_nervous_system1.01071012
80MP0005187_abnormal_penis_morphology1.00723529
81MP0000920_abnormal_myelination1.00210469
82MP0005409_darkened_coat_color0.98004038
83MP0003195_calcinosis0.97837891
84MP0002168_other_aberrant_phenotype0.94960203
85MP0001963_abnormal_hearing_physiology0.93041918
86MP0003121_genomic_imprinting0.91677504
87MP0008961_abnormal_basal_metabolism0.91467944
88MP0004084_abnormal_cardiac_muscle0.91213338
89MP0004145_abnormal_muscle_electrophysio0.91041694
90MP0005220_abnormal_exocrine_pancreas0.89587361
91MP0000427_abnormal_hair_cycle0.87666238
92MP0002127_abnormal_cardiovascular_syste0.86587110
93MP0002152_abnormal_brain_morphology0.86042338
94MP0008789_abnormal_olfactory_epithelium0.85023318
95MP0002160_abnormal_reproductive_system0.84729887
96MP0001485_abnormal_pinna_reflex0.84504032
97MP0002638_abnormal_pupillary_reflex0.83377787
98MP0005195_abnormal_posterior_eye0.82072187
99MP0004085_abnormal_heartbeat0.81640183
100MP0002752_abnormal_somatic_nervous0.81439521
101MP0001944_abnormal_pancreas_morphology0.80910973
102MP0001929_abnormal_gametogenesis0.80868021
103MP0003634_abnormal_glial_cell0.80439412
104MP0003861_abnormal_nervous_system0.80346415
105MP0002069_abnormal_eating/drinking_beha0.79455871
106MP0003119_abnormal_digestive_system0.77623714
107MP0005171_absent_coat_pigmentation0.73736278
108MP0004510_myositis0.72667103
109MP0005310_abnormal_salivary_gland0.72173835
110MP0002928_abnormal_bile_duct0.71978342
111MP0002233_abnormal_nose_morphology0.71237829
112MP0003283_abnormal_digestive_organ0.71127612
113MP0003300_gastrointestinal_ulcer0.69957479
114MP0003699_abnormal_female_reproductive0.69118040
115MP0001324_abnormal_eye_pigmentation0.68510676
116MP0000631_abnormal_neuroendocrine_gland0.67926758
117MP0003329_amyloid_beta_deposits0.66685796
118MP0004484_altered_response_of0.66347398
119MP0000013_abnormal_adipose_tissue0.65922971
120MP0008874_decreased_physiological_sensi0.64942826
121MP0004134_abnormal_chest_morphology0.64747436
122MP0005535_abnormal_body_temperature0.62869260
123MP0003122_maternal_imprinting0.62712276
124MP0004215_abnormal_myocardial_fiber0.62547947
125MP0003172_abnormal_lysosome_physiology0.59051379
126MP0005379_endocrine/exocrine_gland_phen0.58830295
127MP0003698_abnormal_male_reproductive0.57203193
128MP0004858_abnormal_nervous_system0.56487287
129MP0005410_abnormal_fertilization0.56407393
130MP0010678_abnormal_skin_adnexa0.56050433

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.06656676
2Febrile seizures (HP:0002373)4.53487291
3Papillary thyroid carcinoma (HP:0002895)4.41452414
4Epileptic encephalopathy (HP:0200134)4.01728455
5Focal seizures (HP:0007359)3.93645932
6Progressive cerebellar ataxia (HP:0002073)3.92301428
7Atonic seizures (HP:0010819)3.26678036
8Gaze-evoked nystagmus (HP:0000640)3.09905927
9Congenital stationary night blindness (HP:0007642)3.05746669
10Hepatoblastoma (HP:0002884)2.99759784
11Hyperventilation (HP:0002883)2.95664326
12Broad-based gait (HP:0002136)2.88789552
13Genetic anticipation (HP:0003743)2.85778778
14Absence seizures (HP:0002121)2.83324888
15Absent frontal sinuses (HP:0002688)2.80922108
16Thyroid carcinoma (HP:0002890)2.79723850
17Excessive salivation (HP:0003781)2.77514293
18Drooling (HP:0002307)2.77514293
19Action tremor (HP:0002345)2.76294991
20Oligodactyly (hands) (HP:0001180)2.73503004
21Abnormal pancreas size (HP:0012094)2.68077713
22Absent speech (HP:0001344)2.65927984
23Dialeptic seizures (HP:0011146)2.62681589
24Scanning speech (HP:0002168)2.61050347
25Truncal ataxia (HP:0002078)2.58882366
26Central scotoma (HP:0000603)2.57799129
27Widely spaced teeth (HP:0000687)2.55372510
28Protruding tongue (HP:0010808)2.45261479
29Urinary bladder sphincter dysfunction (HP:0002839)2.44920173
30Macroorchidism (HP:0000053)2.38290271
31Generalized hypopigmentation of hair (HP:0011358)2.35424860
32Dysdiadochokinesis (HP:0002075)2.35293912
33Generalized tonic-clonic seizures (HP:0002069)2.35132612
34Chronic hepatic failure (HP:0100626)2.33772288
35Abnormality of the astrocytes (HP:0100707)2.31077025
36Astrocytoma (HP:0009592)2.31077025
37Visual hallucinations (HP:0002367)2.29876274
38Hypoplastic labia majora (HP:0000059)2.26804159
39Intestinal atresia (HP:0011100)2.26023284
40Impaired smooth pursuit (HP:0007772)2.24610777
41Fair hair (HP:0002286)2.24278995
42Blue irides (HP:0000635)2.23541222
43Supranuclear gaze palsy (HP:0000605)2.23157190
44Abnormality of ocular smooth pursuit (HP:0000617)2.19260287
45Labial hypoplasia (HP:0000066)2.17209249
46Abnormality of the renal medulla (HP:0100957)2.16856131
47Dysmetria (HP:0001310)2.13959849
48Diplopia (HP:0000651)2.13787647
49Abnormality of binocular vision (HP:0011514)2.13787647
50Aqueductal stenosis (HP:0002410)2.13767053
51Hemiparesis (HP:0001269)2.10614576
52Abnormality of the labia minora (HP:0012880)2.09059352
53Myokymia (HP:0002411)2.08168929
54Degeneration of the lateral corticospinal tracts (HP:0002314)2.07241142
55Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.07241142
56Impaired vibration sensation in the lower limbs (HP:0002166)2.07015227
57Anterior segment dysgenesis (HP:0007700)2.06764721
58Abnormality of the fingertips (HP:0001211)2.06134704
59Abnormality of the labia majora (HP:0012881)2.05761791
60Papilledema (HP:0001085)2.04648388
61Dyschromatopsia (HP:0007641)2.03786327
62Abnormality of salivation (HP:0100755)2.03479973
63Postural instability (HP:0002172)2.02989711
64Gonadotropin excess (HP:0000837)2.02512196
65Abnormality of incisor morphology (HP:0011063)2.02474322
66Bony spicule pigmentary retinopathy (HP:0007737)2.01388992
67Bundle branch block (HP:0011710)2.01000551
68Genital tract atresia (HP:0001827)2.00735049
69Aplasia involving bones of the upper limbs (HP:0009823)1.99255790
70Aplasia of the phalanges of the hand (HP:0009802)1.99255790
71Aplasia involving bones of the extremities (HP:0009825)1.99255790
72Medial flaring of the eyebrow (HP:0010747)1.99161144
73Intention tremor (HP:0002080)1.98226652
74Abnormal hair whorl (HP:0010721)1.96261662
75Pancreatic fibrosis (HP:0100732)1.96166071
76Abnormality of the nasal septum (HP:0000419)1.95671185
77Epileptiform EEG discharges (HP:0011182)1.94817236
78Heterotopia (HP:0002282)1.94370479
79Syncope (HP:0001279)1.94081239
80Hemiplegia (HP:0002301)1.93588311
81Abnormal respiratory motile cilium morphology (HP:0005938)1.91205046
82Abnormal respiratory epithelium morphology (HP:0012253)1.91205046
83Decreased central vision (HP:0007663)1.90979125
84Absent/shortened dynein arms (HP:0200106)1.90939467
85Dynein arm defect of respiratory motile cilia (HP:0012255)1.90939467
86Volvulus (HP:0002580)1.90018215
87Pancreatic cysts (HP:0001737)1.88483228
88Thyroiditis (HP:0100646)1.87528673
89Inappropriate behavior (HP:0000719)1.87267721
90Fibular hypoplasia (HP:0003038)1.87215216
91EEG with generalized epileptiform discharges (HP:0011198)1.86791479
92Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.86293915
93Tubulointerstitial abnormality (HP:0001969)1.85707782
94Abnormality of the renal cortex (HP:0011035)1.85686775
95Neurofibrillary tangles (HP:0002185)1.82553474
96Mutism (HP:0002300)1.80780419
97Rhinitis (HP:0012384)1.80376388
98Abnormality of the corticospinal tract (HP:0002492)1.80229787
99Cutaneous finger syndactyly (HP:0010554)1.80130147
100Open mouth (HP:0000194)1.79684336
101Abnormality of macular pigmentation (HP:0008002)1.79099943
102Supernumerary spleens (HP:0009799)1.78507365
103Abnormal biliary tract morphology (HP:0012440)1.77211157
104Vaginal atresia (HP:0000148)1.77020776
105Neonatal hypoglycemia (HP:0001998)1.76791051
106Abnormality of midbrain morphology (HP:0002418)1.76421509
107Molar tooth sign on MRI (HP:0002419)1.76421509
108Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.76408779
109Abnormality of chromosome segregation (HP:0002916)1.76228724
110Clumsiness (HP:0002312)1.75578100
111Rhabdomyosarcoma (HP:0002859)1.73920813
112Narrow palate (HP:0000189)1.73780551
113Enlarged penis (HP:0000040)1.73453588
114Hypoplastic female external genitalia (HP:0012815)1.73441031
115Abnormal social behavior (HP:0012433)1.73279397
116Impaired social interactions (HP:0000735)1.73279397
117Chronic diarrhea (HP:0002028)1.73225170
118Tubulointerstitial nephritis (HP:0001970)1.72059378
119Truncal obesity (HP:0001956)1.71397165
120Congenital primary aphakia (HP:0007707)1.70836007
121Dysmetric saccades (HP:0000641)1.70262300
122Lip pit (HP:0100267)1.70072009
123Poor coordination (HP:0002370)1.69308759
124Impaired vibratory sensation (HP:0002495)1.69210954
125Neoplasm of striated muscle (HP:0009728)1.68884066
126Renal cortical cysts (HP:0000803)1.68754888
127Poor eye contact (HP:0000817)1.68476028
128Scotoma (HP:0000575)1.68081512
129Medulloblastoma (HP:0002885)1.67886108
130Exotropia (HP:0000577)1.67561839
131Deeply set eye (HP:0000490)1.67126437
132Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.67059608
133Abnormality of the frontal sinuses (HP:0002687)1.66899488
134Glioma (HP:0009733)1.65929025
135Increased circulating renin level (HP:0000848)1.65712149
136Spastic gait (HP:0002064)1.65563224
137Abnormality of abdominal situs (HP:0011620)1.65555348
138Abdominal situs inversus (HP:0003363)1.65555348
139Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.65477108
140Hypsarrhythmia (HP:0002521)1.65352290
141Narrow forehead (HP:0000341)1.65254482
142Abnormal ciliary motility (HP:0012262)1.65203445
143Neuronal loss in central nervous system (HP:0002529)1.64959970
144Thickened helices (HP:0000391)1.64613170
145Abnormality of saccadic eye movements (HP:0000570)1.63779234
146Neoplasm of the adrenal cortex (HP:0100641)1.63554676
147Progressive inability to walk (HP:0002505)1.62743816
148Hyperkalemia (HP:0002153)1.61860018
149Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.61657585
150Abnormal respiratory motile cilium physiology (HP:0012261)1.60813122
151Nephronophthisis (HP:0000090)1.60767994
152Gait imbalance (HP:0002141)1.60649651

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.52302056
2TNIK2.95080305
3MAP3K42.71801748
4BMPR1B2.54937739
5CAMK1G2.46485544
6EPHA42.33861027
7CASK2.32409672
8NTRK22.21137102
9WNK32.20659082
10INSRR2.08953690
11CAMK1D2.06144950
12MAP2K72.05958515
13SIK21.94906945
14MAP3K91.77016771
15MAP3K131.75162585
16SGK21.74103560
17MARK11.64982711
18MAP4K21.60417042
19FGFR21.53981825
20RIPK41.52326019
21FRK1.50465434
22BMPR21.48218534
23CAMKK21.45389391
24SGK31.44956508
25PRPF4B1.42079011
26SGK4941.39548407
27SGK2231.39548407
28MAPK131.33381011
29BCR1.30216691
30NUAK11.29947462
31MAP2K41.27202292
32NLK1.26014906
33WNK11.25071228
34STK241.20994153
35PNCK1.20673342
36DAPK21.16297857
37STK31.13455870
38ACVR1B1.13110914
39PRKCH1.11651397
40FGFR31.10424871
41PAK61.05854954
42NEK61.05847439
43SGK11.05428427
44TAOK31.03473074
45AKT31.01496693
46JAK11.00723220
47CDK51.00611351
48PINK11.00563569
49CDK30.95885612
50MARK20.95393393
51CAMKK10.94807432
52PKN10.93761559
53MKNK20.93221905
54OBSCN0.89969480
55SIK30.88897192
56MAP3K60.86482275
57SIK10.85997163
58GRK10.84722180
59CAMK40.82761251
60FES0.82458254
61PRKCZ0.82287144
62UHMK10.80951619
63BRD40.79864027
64IRAK10.79828957
65KSR10.79358976
66MAPK70.79001366
67TXK0.78876205
68DMPK0.78817039
69MAP3K70.78352847
70CDK120.77790565
71MINK10.77164626
72EIF2AK30.76662934
73STK380.75974782
74RPS6KB10.75049553
75STK110.74291610
76NEK90.73228110
77LATS10.73165434
78EPHA30.72963287
79CSNK1G10.71285871
80FGR0.69555772
81CDK190.69257242
82RET0.68928920
83CDC42BPA0.68765335
84DYRK1A0.68615305
85CSNK1D0.67467089
86PIK3CA0.66988032
87CAMK2A0.66954713
88STK390.66946166
89PLK20.65454450
90PRKCQ0.64748822
91CAMK10.64409805
92MAP3K20.64191070
93MAP3K120.63452788
94CSNK1G20.63299711
95NTRK10.62951552
96PDK10.62217514
97PRKCE0.61304208
98ERBB20.61268985
99PRKCG0.61013346
100PDGFRB0.59804393
101PRKD30.59748572
102MAP3K50.57428369
103MET0.57181841
104ERBB30.56909785
105PRKAA20.56149830
106OXSR10.55805239
107PRKAA10.55660397
108MAP3K140.54442214
109ITK0.54116032
110GRK70.53744051
111RIPK10.53354707
112CSNK1A1L0.53267597
113CAMK2B0.52811980
114CDK90.51779503
115RPS6KA30.51368735
116RAF10.50997616
117STK38L0.49024367
118PRKG10.47656985
119MAPK100.47290075
120YES10.46415010
121HIPK20.46238299
122PRKCB0.44938911
123FYN0.43422764
124CAMK2D0.43021218
125PTK2B0.42777522
126PDPK10.42775512
127PAK30.42555944
128FGFR10.41956749
129FER0.41680885
130PHKG10.41475958
131PHKG20.41475958
132TNK20.41168807
133EGFR0.40273348
134TRPM70.40260131

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.15208683
2Circadian entrainment_Homo sapiens_hsa047132.26255038
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.25406473
4Morphine addiction_Homo sapiens_hsa050322.18394833
5Glutamatergic synapse_Homo sapiens_hsa047242.17345758
6GABAergic synapse_Homo sapiens_hsa047272.09522987
7Phototransduction_Homo sapiens_hsa047442.02157661
8Long-term potentiation_Homo sapiens_hsa047201.93649595
9Olfactory transduction_Homo sapiens_hsa047401.85764914
10Salivary secretion_Homo sapiens_hsa049701.84765135
11Insulin secretion_Homo sapiens_hsa049111.77602736
12Synaptic vesicle cycle_Homo sapiens_hsa047211.75345117
13Taste transduction_Homo sapiens_hsa047421.74472000
14Amphetamine addiction_Homo sapiens_hsa050311.70097006
15Type II diabetes mellitus_Homo sapiens_hsa049301.66346982
16Phosphatidylinositol signaling system_Homo sapiens_hsa040701.66025444
17Renin secretion_Homo sapiens_hsa049241.60176907
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.56976816
19Cholinergic synapse_Homo sapiens_hsa047251.56449846
20Dopaminergic synapse_Homo sapiens_hsa047281.53924697
21Long-term depression_Homo sapiens_hsa047301.46426562
22Dorso-ventral axis formation_Homo sapiens_hsa043201.46229242
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.45754021
24Serotonergic synapse_Homo sapiens_hsa047261.45238263
25Gastric acid secretion_Homo sapiens_hsa049711.42902793
26Calcium signaling pathway_Homo sapiens_hsa040201.39903384
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.39143964
28Oxytocin signaling pathway_Homo sapiens_hsa049211.33405239
29cAMP signaling pathway_Homo sapiens_hsa040241.29931975
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.21176357
31Oocyte meiosis_Homo sapiens_hsa041141.20828971
32Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.20673493
33Cocaine addiction_Homo sapiens_hsa050301.15915894
34cGMP-PKG signaling pathway_Homo sapiens_hsa040221.13599351
35Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.12448326
36GnRH signaling pathway_Homo sapiens_hsa049121.12343191
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10097944
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.07968275
39Inositol phosphate metabolism_Homo sapiens_hsa005621.05592822
40Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05224100
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.05092906
42Carbohydrate digestion and absorption_Homo sapiens_hsa049730.99925989
43Vascular smooth muscle contraction_Homo sapiens_hsa042700.98002282
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.96278761
45Adherens junction_Homo sapiens_hsa045200.96110258
46Axon guidance_Homo sapiens_hsa043600.95338828
47ErbB signaling pathway_Homo sapiens_hsa040120.94276900
48Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93944770
49Choline metabolism in cancer_Homo sapiens_hsa052310.91897996
50Circadian rhythm_Homo sapiens_hsa047100.90407320
51MAPK signaling pathway_Homo sapiens_hsa040100.87984568
52Pancreatic secretion_Homo sapiens_hsa049720.87523438
53Linoleic acid metabolism_Homo sapiens_hsa005910.87476575
54Estrogen signaling pathway_Homo sapiens_hsa049150.85448802
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.84986902
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84085299
57Regulation of autophagy_Homo sapiens_hsa041400.83845336
58Dilated cardiomyopathy_Homo sapiens_hsa054140.81164057
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80889824
60Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80740573
61Glioma_Homo sapiens_hsa052140.80519278
62Gap junction_Homo sapiens_hsa045400.79897647
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.78548576
64Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78411205
65Ovarian steroidogenesis_Homo sapiens_hsa049130.77548556
66Tight junction_Homo sapiens_hsa045300.72885400
67T cell receptor signaling pathway_Homo sapiens_hsa046600.71469587
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70789309
69Butanoate metabolism_Homo sapiens_hsa006500.70460615
70Thyroid hormone synthesis_Homo sapiens_hsa049180.69753932
71alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69562779
72Caffeine metabolism_Homo sapiens_hsa002320.68778093
73Thyroid hormone signaling pathway_Homo sapiens_hsa049190.67783852
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67640225
75ABC transporters_Homo sapiens_hsa020100.65525828
76Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65376061
77Chemokine signaling pathway_Homo sapiens_hsa040620.64804048
78Ras signaling pathway_Homo sapiens_hsa040140.64489538
79Melanogenesis_Homo sapiens_hsa049160.63736772
80Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62964326
81Fatty acid biosynthesis_Homo sapiens_hsa000610.61687649
82Mineral absorption_Homo sapiens_hsa049780.61023722
83Basal transcription factors_Homo sapiens_hsa030220.60150423
84Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59593325
85African trypanosomiasis_Homo sapiens_hsa051430.59469558
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.57676571
87Non-small cell lung cancer_Homo sapiens_hsa052230.57078491
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56551160
89mTOR signaling pathway_Homo sapiens_hsa041500.56211664
90Histidine metabolism_Homo sapiens_hsa003400.55422105
91Glucagon signaling pathway_Homo sapiens_hsa049220.55180370
92Rap1 signaling pathway_Homo sapiens_hsa040150.53516072
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53479843
94mRNA surveillance pathway_Homo sapiens_hsa030150.53097623
95Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53057008
96TGF-beta signaling pathway_Homo sapiens_hsa043500.52769847
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51999805
98Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51979940
99AMPK signaling pathway_Homo sapiens_hsa041520.50923910
100Alcoholism_Homo sapiens_hsa050340.50919521
101Hippo signaling pathway_Homo sapiens_hsa043900.48952319
102Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48692376
103Bile secretion_Homo sapiens_hsa049760.48629504
104Osteoclast differentiation_Homo sapiens_hsa043800.48550362
105Hedgehog signaling pathway_Homo sapiens_hsa043400.47839852
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.47555856
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.47062009
108Lysine degradation_Homo sapiens_hsa003100.47040996
109FoxO signaling pathway_Homo sapiens_hsa040680.47038265
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.46828805
111Type I diabetes mellitus_Homo sapiens_hsa049400.46289417
112Endometrial cancer_Homo sapiens_hsa052130.45810005
113Collecting duct acid secretion_Homo sapiens_hsa049660.45647690
114Wnt signaling pathway_Homo sapiens_hsa043100.45311014
115Colorectal cancer_Homo sapiens_hsa052100.44741245
116Platelet activation_Homo sapiens_hsa046110.44207504
117Prolactin signaling pathway_Homo sapiens_hsa049170.44059534
118Sphingolipid metabolism_Homo sapiens_hsa006000.43381454
119Pancreatic cancer_Homo sapiens_hsa052120.39813784
120Insulin resistance_Homo sapiens_hsa049310.39071220
121B cell receptor signaling pathway_Homo sapiens_hsa046620.35940806
122Ether lipid metabolism_Homo sapiens_hsa005650.34355277
123Insulin signaling pathway_Homo sapiens_hsa049100.34007771
124Renal cell carcinoma_Homo sapiens_hsa052110.33633683

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