DPH6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA double-strand break processing (GO:0000729)4.25532279
2CENP-A containing nucleosome assembly (GO:0034080)3.95619974
3attachment of spindle microtubules to kinetochore (GO:0008608)3.89920467
4kinetochore organization (GO:0051383)3.78939975
5chromatin remodeling at centromere (GO:0031055)3.74568302
6water-soluble vitamin biosynthetic process (GO:0042364)3.65231044
7protein complex biogenesis (GO:0070271)3.65038178
8DNA deamination (GO:0045006)3.61904251
9kinetochore assembly (GO:0051382)3.57936669
10synapsis (GO:0007129)3.51894201
11rRNA modification (GO:0000154)3.49832140
12establishment of protein localization to mitochondrial membrane (GO:0090151)3.46276762
13mitotic metaphase plate congression (GO:0007080)3.45029260
14mitochondrial respiratory chain complex assembly (GO:0033108)3.41778485
15mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.41706731
16mitochondrial respiratory chain complex I assembly (GO:0032981)3.41706731
17NADH dehydrogenase complex assembly (GO:0010257)3.41706731
18termination of RNA polymerase III transcription (GO:0006386)3.40908581
19transcription elongation from RNA polymerase III promoter (GO:0006385)3.40908581
20pseudouridine synthesis (GO:0001522)3.39380102
21telomere maintenance via recombination (GO:0000722)3.33280543
22rRNA methylation (GO:0031167)3.30786039
23maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.30478950
24telomere maintenance via semi-conservative replication (GO:0032201)3.27612296
25DNA replication-independent nucleosome organization (GO:0034724)3.27301635
26DNA replication-independent nucleosome assembly (GO:0006336)3.27301635
27establishment of chromosome localization (GO:0051303)3.22618436
28mitotic recombination (GO:0006312)3.21813444
29platelet dense granule organization (GO:0060155)3.21679372
30proteasome assembly (GO:0043248)3.21482354
31metaphase plate congression (GO:0051310)3.20875327
32DNA replication checkpoint (GO:0000076)3.20011914
33ribosomal small subunit assembly (GO:0000028)3.19109329
34centriole replication (GO:0007099)3.16836695
35mitotic chromosome condensation (GO:0007076)3.15402504
36recombinational repair (GO:0000725)3.15150619
37mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.14712785
38tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.14115181
39RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.14115181
40double-strand break repair via homologous recombination (GO:0000724)3.13229261
41meiotic chromosome segregation (GO:0045132)3.13080305
42protein neddylation (GO:0045116)3.11929557
43protein prenylation (GO:0018342)3.11877776
44prenylation (GO:0097354)3.11877776
45DNA strand elongation involved in DNA replication (GO:0006271)3.08547746
46signal peptide processing (GO:0006465)3.07833207
47resolution of meiotic recombination intermediates (GO:0000712)3.07319874
48respiratory chain complex IV assembly (GO:0008535)3.06706848
49histone exchange (GO:0043486)3.06674438
50nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.06568386
51replication fork processing (GO:0031297)3.05394519
52DNA replication initiation (GO:0006270)3.05216490
53branched-chain amino acid catabolic process (GO:0009083)3.04747869
54deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.03416756
55regulation of meiosis I (GO:0060631)3.02634281
56exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.00959789
57cellular ketone body metabolic process (GO:0046950)3.00918133
58DNA strand elongation (GO:0022616)3.00565080
59L-fucose catabolic process (GO:0042355)3.00365383
60fucose catabolic process (GO:0019317)3.00365383
61L-fucose metabolic process (GO:0042354)3.00365383
62endosome to pigment granule transport (GO:0043485)3.00139573
63endosome to melanosome transport (GO:0035646)3.00139573
64protein deneddylation (GO:0000338)2.98869138
65RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.98678526
66guanosine-containing compound biosynthetic process (GO:1901070)2.98667951
67intraciliary transport (GO:0042073)2.97413399
68protein K6-linked ubiquitination (GO:0085020)2.96836732
69mismatch repair (GO:0006298)2.93720482
707-methylguanosine mRNA capping (GO:0006370)2.93625531
71intra-S DNA damage checkpoint (GO:0031573)2.93124014
72DNA catabolic process, exonucleolytic (GO:0000738)2.91835805
737-methylguanosine RNA capping (GO:0009452)2.91537242
74RNA capping (GO:0036260)2.91537242
75preassembly of GPI anchor in ER membrane (GO:0016254)2.89991799
76regulation of pigment cell differentiation (GO:0050932)2.89934692
77GTP biosynthetic process (GO:0006183)2.89627631
78regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.89267011
79negative regulation of DNA-dependent DNA replication (GO:2000104)2.87448024
80cilium morphogenesis (GO:0060271)2.87364297
81somatic diversification of immune receptors via somatic mutation (GO:0002566)2.86160074
82somatic hypermutation of immunoglobulin genes (GO:0016446)2.86160074
83detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.85223066
84DNA strand renaturation (GO:0000733)2.84275162
85spindle assembly checkpoint (GO:0071173)2.84236398
86transcription-coupled nucleotide-excision repair (GO:0006283)2.84042247
87mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.83925387
88negative regulation of mitotic sister chromatid separation (GO:2000816)2.83469495
89negative regulation of mitotic sister chromatid segregation (GO:0033048)2.83469495
90negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.83469495
91negative regulation of sister chromatid segregation (GO:0033046)2.83469495
92negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.83463248
93lactate metabolic process (GO:0006089)2.82276859
94regulation of nuclear cell cycle DNA replication (GO:0033262)2.81145712
95mitotic spindle assembly checkpoint (GO:0007094)2.80995351
96spindle checkpoint (GO:0031577)2.80568379
97purine nucleobase biosynthetic process (GO:0009113)2.78562642
98nucleobase biosynthetic process (GO:0046112)2.78171731
99telomere maintenance via telomere lengthening (GO:0010833)2.77282778
100spliceosomal complex assembly (GO:0000245)2.76316841
101indolalkylamine metabolic process (GO:0006586)2.76189314
102regulation of mitotic spindle checkpoint (GO:1903504)2.75857038
103regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.75857038
104anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.75596245
105negative regulation of chromosome segregation (GO:0051985)2.75275362
106tryptophan catabolic process (GO:0006569)2.74902868
107indole-containing compound catabolic process (GO:0042436)2.74902868
108indolalkylamine catabolic process (GO:0046218)2.74902868
109regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.73951154
110maturation of 5.8S rRNA (GO:0000460)2.71738205
111regulation of acyl-CoA biosynthetic process (GO:0050812)2.71499925
112nucleotide-excision repair, DNA gap filling (GO:0006297)2.71352565
113negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.70816732
114ketone body metabolic process (GO:1902224)2.70136871
115chaperone-mediated protein transport (GO:0072321)2.69878008
116establishment of integrated proviral latency (GO:0075713)2.69717944
117mitotic sister chromatid cohesion (GO:0007064)2.68280323
118regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.68067416
119histone H2A acetylation (GO:0043968)2.67867995
120regulation of mitotic metaphase/anaphase transition (GO:0030071)2.67714168
121regulation of cilium movement (GO:0003352)2.67256692
122mitotic spindle checkpoint (GO:0071174)2.66371524
123positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.66310321
124photoreceptor cell maintenance (GO:0045494)2.66240140
125ribosome biogenesis (GO:0042254)2.66198046
126RNA methylation (GO:0001510)2.64796161
127histone mRNA metabolic process (GO:0008334)2.64786904
128L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.63792139
129regulation of sister chromatid segregation (GO:0033045)2.63098822
130regulation of mitotic sister chromatid separation (GO:0010965)2.63098822
131regulation of mitotic sister chromatid segregation (GO:0033047)2.63098822
132cytochrome complex assembly (GO:0017004)2.62715952
133tryptophan metabolic process (GO:0006568)2.62681921
134epithelial cilium movement (GO:0003351)2.62613298
135UTP biosynthetic process (GO:0006228)2.62607074
136response to pheromone (GO:0019236)2.61852271
137somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.61387621
138somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.61387621
139isotype switching (GO:0045190)2.61387621
140negative regulation of transcription regulatory region DNA binding (GO:2000678)2.60373011
141DNA synthesis involved in DNA repair (GO:0000731)2.60120334
142retinal cone cell development (GO:0046549)2.59280631
143behavioral response to nicotine (GO:0035095)2.58515377
144reciprocal meiotic recombination (GO:0007131)2.58112511
145reciprocal DNA recombination (GO:0035825)2.58112511
146mitotic nuclear envelope disassembly (GO:0007077)2.58054429
147cullin deneddylation (GO:0010388)2.57816673
148spliceosomal snRNP assembly (GO:0000387)2.56082508
149regulation of double-strand break repair via homologous recombination (GO:0010569)2.55840767
150regulation of hexokinase activity (GO:1903299)2.54837974
151regulation of glucokinase activity (GO:0033131)2.54837974
152tRNA methylation (GO:0030488)2.54579570
153intracellular protein transmembrane import (GO:0044743)2.54249588
154protein localization to cilium (GO:0061512)2.54196669
155negative regulation of mitosis (GO:0045839)2.53620166
156sister chromatid cohesion (GO:0007062)2.52709185
157chromosome segregation (GO:0007059)2.52540553
158viral mRNA export from host cell nucleus (GO:0046784)2.52465554
159cilium organization (GO:0044782)2.50117960
160positive regulation of histone H3-K4 methylation (GO:0051571)2.49904706
161regulation of DNA endoreduplication (GO:0032875)2.49356421
162otic vesicle formation (GO:0030916)2.49050565
163ATP synthesis coupled proton transport (GO:0015986)2.47953007
164energy coupled proton transport, down electrochemical gradient (GO:0015985)2.47953007
165C-terminal protein amino acid modification (GO:0018410)2.47799594
166single strand break repair (GO:0000012)2.47117645
167C-terminal protein lipidation (GO:0006501)2.46516013
168axoneme assembly (GO:0035082)2.46228355
169nonmotile primary cilium assembly (GO:0035058)2.45891320
170regulation of mitochondrial translation (GO:0070129)2.45491240
171DNA replication-dependent nucleosome organization (GO:0034723)2.45388185
172DNA replication-dependent nucleosome assembly (GO:0006335)2.45388185
173neural tube formation (GO:0001841)2.45035515

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.42365477
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.02310754
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.52455409
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.43722916
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.38605023
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.34312157
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.23201663
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.09154685
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.06189661
10ZNF274_21170338_ChIP-Seq_K562_Hela3.00858262
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79041119
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.77236202
13VDR_22108803_ChIP-Seq_LS180_Human2.76600273
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.61945351
15GBX2_23144817_ChIP-Seq_PC3_Human2.54660678
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.50744954
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.45301185
18VDR_23849224_ChIP-Seq_CD4+_Human2.44320117
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.43326407
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.42955081
21MYC_19030024_ChIP-ChIP_MESCs_Mouse2.38086013
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.35228154
23ELK1_19687146_ChIP-ChIP_HELA_Human2.33288874
24PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.32783968
25MYC_18358816_ChIP-ChIP_MESCs_Mouse2.28063588
26FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.25831470
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.23213294
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.20159302
29CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.19514356
30TAF15_26573619_Chip-Seq_HEK293_Human2.17525199
31SRF_21415370_ChIP-Seq_HL-1_Mouse2.16671743
32FOXP3_21729870_ChIP-Seq_TREG_Human2.14498816
33YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.09260334
34CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.06583910
35CREB1_15753290_ChIP-ChIP_HEK293T_Human2.05085118
36P300_19829295_ChIP-Seq_ESCs_Human2.04802974
37NELFA_20434984_ChIP-Seq_ESCs_Mouse2.01753032
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.00276607
39GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.00103996
40MYC_19079543_ChIP-ChIP_MESCs_Mouse1.98561249
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.96951823
42E2F1_18555785_ChIP-Seq_MESCs_Mouse1.94525701
43E2F1_21310950_ChIP-Seq_MCF-7_Human1.94503629
44DCP1A_22483619_ChIP-Seq_HELA_Human1.90807209
45EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.90495453
46FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90302789
47KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.87795826
48CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85339332
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.84241260
50MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80988240
51NOTCH1_21737748_ChIP-Seq_TLL_Human1.79257164
52TTF2_22483619_ChIP-Seq_HELA_Human1.76531587
53GABP_19822575_ChIP-Seq_HepG2_Human1.71727430
54AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.71198538
55AR_21909140_ChIP-Seq_LNCAP_Human1.70263985
56MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69004710
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.58295695
58ER_23166858_ChIP-Seq_MCF-7_Human1.56666482
59CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56663843
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.56237241
61FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.55471130
62FUS_26573619_Chip-Seq_HEK293_Human1.55093753
63DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.54441194
64ERG_20887958_ChIP-Seq_HPC-7_Mouse1.53763573
65XRN2_22483619_ChIP-Seq_HELA_Human1.53224608
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.51966605
67EWS_26573619_Chip-Seq_HEK293_Human1.47742810
68UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46957183
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43203225
70EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.41708259
71E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.41085020
72BCAT_22108803_ChIP-Seq_LS180_Human1.40208759
73SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40066327
74SMAD4_21799915_ChIP-Seq_A2780_Human1.38206491
75CIITA_25753668_ChIP-Seq_RAJI_Human1.37656204
76CBP_20019798_ChIP-Seq_JUKART_Human1.35355735
77IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35355735
78NANOG_18555785_ChIP-Seq_MESCs_Mouse1.34755346
79MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.33960193
80SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33486833
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.32655250
82EGR1_19374776_ChIP-ChIP_THP-1_Human1.32516744
83NANOG_19829295_ChIP-Seq_ESCs_Human1.32160512
84SOX2_19829295_ChIP-Seq_ESCs_Human1.32160512
85SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31296172
86TP53_22573176_ChIP-Seq_HFKS_Human1.30422943
87PCGF2_27294783_Chip-Seq_NPCs_Mouse1.30087876
88PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.29966970
89MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.29539842
90POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.29370691
91STAT3_23295773_ChIP-Seq_U87_Human1.28968334
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.24777795
93SALL1_21062744_ChIP-ChIP_HESCs_Human1.24431791
94SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24317701
95AR_25329375_ChIP-Seq_VCAP_Human1.24267550
96TCF4_22108803_ChIP-Seq_LS180_Human1.24251085
97YY1_21170310_ChIP-Seq_MESCs_Mouse1.22647610
98IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.22064081
99FLI1_27457419_Chip-Seq_LIVER_Mouse1.21750849
100POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21255300
101SMAD3_21741376_ChIP-Seq_EPCs_Human1.21140389
102OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21138386
103RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21075220
104ZFX_18555785_ChIP-Seq_MESCs_Mouse1.20972721
105TFEB_21752829_ChIP-Seq_HELA_Human1.20970958
106ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.20838546
107MYC_18940864_ChIP-ChIP_HL60_Human1.20825570
108TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.19483252
109KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18149874
110NANOG_18555785_Chip-Seq_ESCs_Mouse1.17991468
111CRX_20693478_ChIP-Seq_RETINA_Mouse1.17635293
112TCF4_23295773_ChIP-Seq_U87_Human1.17590522
113TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13569018
114TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13369681
115EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13139142
116FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12904055
117FOXA1_25329375_ChIP-Seq_VCAP_Human1.12904055
118GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12902264
119TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12691193
120CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.12221530
121P53_22387025_ChIP-Seq_ESCs_Mouse1.10569859
122ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.10354545
123NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10130325
124FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09511607
125SPI1_23547873_ChIP-Seq_NB4_Human1.09341129
126PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06564431
127CDX2_22108803_ChIP-Seq_LS180_Human1.06102188
128PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.04032804
129E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03295161
130IGF1R_20145208_ChIP-Seq_DFB_Human1.02833392
131SMAD4_21741376_ChIP-Seq_EPCs_Human1.00566178
132E2F1_18555785_Chip-Seq_ESCs_Mouse1.00264366
133KDM5A_27292631_Chip-Seq_BREAST_Human1.00132012
134P300_18555785_Chip-Seq_ESCs_Mouse0.99759875
135EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.99591115
136RUNX2_22187159_ChIP-Seq_PCA_Human0.98912081
137ELK1_22589737_ChIP-Seq_MCF10A_Human0.98764369
138STAT3_18555785_Chip-Seq_ESCs_Mouse0.98704105
139CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97905486
140SUZ12_18555785_Chip-Seq_ESCs_Mouse0.97518288
141SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.97502352
142POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96917029
143POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96837027
144AR_20517297_ChIP-Seq_VCAP_Human0.96080881
145ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.94767503
146BP1_19119308_ChIP-ChIP_Hs578T_Human0.94320375
147OCT4_21477851_ChIP-Seq_ESCs_Mouse0.94055936
148FLI1_21867929_ChIP-Seq_TH2_Mouse0.93540682
149SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.91671830
150BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90730326
151CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.79241477
152GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78909071
153FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76664845
154IRF1_19129219_ChIP-ChIP_H3396_Human0.73357603
155GATA1_22025678_ChIP-Seq_K562_Human0.72047249
156CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.68717641
157EZH2_27294783_Chip-Seq_NPCs_Mouse0.66650571
158SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.66580774
159IRF8_22096565_ChIP-ChIP_GC-B_Human0.66511706
160FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.66019183
161SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.64773705
162SOX2_18555785_ChIP-Seq_MESCs_Mouse0.63615273
163SUZ12_27294783_Chip-Seq_NPCs_Mouse0.61906252
164NFE2_27457419_Chip-Seq_LIVER_Mouse0.61832260

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.45162378
2MP0010094_abnormal_chromosome_stability3.55924843
3MP0001188_hyperpigmentation3.33955522
4MP0006292_abnormal_olfactory_placode3.16278950
5MP0008058_abnormal_DNA_repair3.07241164
6MP0008057_abnormal_DNA_replication2.97531307
7MP0003195_calcinosis2.88157798
8MP0003077_abnormal_cell_cycle2.80462936
9MP0008877_abnormal_DNA_methylation2.75352761
10MP0004957_abnormal_blastocyst_morpholog2.69509333
11MP0003111_abnormal_nucleus_morphology2.67326556
12MP0008007_abnormal_cellular_replicative2.58520382
13MP0002837_dystrophic_cardiac_calcinosis2.55816851
14MP0000015_abnormal_ear_pigmentation2.46218624
15MP0005174_abnormal_tail_pigmentation2.36463345
16MP0003787_abnormal_imprinting2.35860985
17MP0009379_abnormal_foot_pigmentation2.35681346
18MP0005409_darkened_coat_color2.33495516
19MP0003718_maternal_effect2.21678384
20MP0002102_abnormal_ear_morphology2.13939474
21MP0005551_abnormal_eye_electrophysiolog2.10685187
22MP0000678_abnormal_parathyroid_gland2.10063614
23MP0005253_abnormal_eye_physiology1.96887368
24MP0003121_genomic_imprinting1.83265385
25MP0008932_abnormal_embryonic_tissue1.81635042
26MP0001986_abnormal_taste_sensitivity1.78724375
27MP0009697_abnormal_copulation1.78544220
28MP0000569_abnormal_digit_pigmentation1.78247288
29MP0002396_abnormal_hematopoietic_system1.76332381
30MP0003786_premature_aging1.73785705
31MP0000427_abnormal_hair_cycle1.68957445
32MP0008995_early_reproductive_senescence1.68452954
33MP0002938_white_spotting1.68019584
34MP0003123_paternal_imprinting1.63153424
35MP0001984_abnormal_olfaction1.59327732
36MP0003011_delayed_dark_adaptation1.58612394
37MP0002095_abnormal_skin_pigmentation1.51373077
38MP0005646_abnormal_pituitary_gland1.50766793
39MP0002877_abnormal_melanocyte_morpholog1.50130133
40MP0005084_abnormal_gallbladder_morpholo1.47834996
41MP0002254_reproductive_system_inflammat1.45519994
42MP0002736_abnormal_nociception_after1.45114547
43MP0002638_abnormal_pupillary_reflex1.41587392
44MP0004215_abnormal_myocardial_fiber1.41002354
45MP0004808_abnormal_hematopoietic_stem1.40404886
46MP0001293_anophthalmia1.38675364
47MP0001919_abnormal_reproductive_system1.36490518
48MP0004147_increased_porphyrin_level1.35229907
49MP0010030_abnormal_orbit_morphology1.34105826
50MP0003806_abnormal_nucleotide_metabolis1.33486264
51MP0006036_abnormal_mitochondrial_physio1.31424306
52MP0005075_abnormal_melanosome_morpholog1.31036775
53MP0002163_abnormal_gland_morphology1.30658863
54MP0001968_abnormal_touch/_nociception1.30164002
55MP0003763_abnormal_thymus_physiology1.28723340
56MP0000383_abnormal_hair_follicle1.28427666
57MP0009046_muscle_twitch1.28407571
58MP0001119_abnormal_female_reproductive1.27190520
59MP0004264_abnormal_extraembryonic_tissu1.24823475
60MP0001485_abnormal_pinna_reflex1.24556951
61MP0008872_abnormal_physiological_respon1.24388545
62MP0010386_abnormal_urinary_bladder1.24217470
63MP0005379_endocrine/exocrine_gland_phen1.24010899
64MP0000490_abnormal_crypts_of1.23586136
65MP0006035_abnormal_mitochondrial_morpho1.23077030
66MP0000350_abnormal_cell_proliferation1.21565128
67MP0005389_reproductive_system_phenotype1.21382064
68MP0003880_abnormal_central_pattern1.20905309
69MP0008789_abnormal_olfactory_epithelium1.19920045
70MP0000516_abnormal_urinary_system1.19338049
71MP0005367_renal/urinary_system_phenotyp1.19338049
72MP0004133_heterotaxia1.16973493
73MP0000647_abnormal_sebaceous_gland1.16346937
74MP0005645_abnormal_hypothalamus_physiol1.15851262
75MP0002876_abnormal_thyroid_physiology1.15117408
76MP0000372_irregular_coat_pigmentation1.14651496
77MP0002210_abnormal_sex_determination1.14198583
78MP0003943_abnormal_hepatobiliary_system1.13332704
79MP0006072_abnormal_retinal_apoptosis1.11559251
80MP0006276_abnormal_autonomic_nervous1.10585021
81MP0002751_abnormal_autonomic_nervous1.09738383
82MP0006054_spinal_hemorrhage1.07809529
83MP0000049_abnormal_middle_ear1.07613070
84MP0004142_abnormal_muscle_tone1.07311191
85MP0002177_abnormal_outer_ear1.06222468
86MP0000313_abnormal_cell_death1.06211505
87MP0003136_yellow_coat_color1.05964996
88MP0002160_abnormal_reproductive_system1.05623890
89MP0000681_abnormal_thyroid_gland1.05449417
90MP0003183_abnormal_peptide_metabolism1.05440685
91MP0003890_abnormal_embryonic-extraembry1.03837407
92MP0002090_abnormal_vision1.02537640
93MP0005171_absent_coat_pigmentation1.01882503
94MP0003567_abnormal_fetal_cardiomyocyte0.99762169
95MP0003937_abnormal_limbs/digits/tail_de0.98947678
96MP0001764_abnormal_homeostasis0.97239717
97MP0001697_abnormal_embryo_size0.97070406
98MP0000566_synostosis0.95689589
99MP0001486_abnormal_startle_reflex0.95568020
100MP0001929_abnormal_gametogenesis0.94680045
101MP0005332_abnormal_amino_acid0.92808677
102MP0001730_embryonic_growth_arrest0.92045538
103MP0009745_abnormal_behavioral_response0.91974423
104MP0000653_abnormal_sex_gland0.91784051
105MP0001186_pigmentation_phenotype0.90319299
106MP0003137_abnormal_impulse_conducting0.89996016
107MP0003698_abnormal_male_reproductive0.89860969
108MP0002249_abnormal_larynx_morphology0.89519557
109MP0005394_taste/olfaction_phenotype0.89267646
110MP0005499_abnormal_olfactory_system0.89267646
111MP0005410_abnormal_fertilization0.88246795
112MP0000631_abnormal_neuroendocrine_gland0.87540379
113MP0005391_vision/eye_phenotype0.86069285
114MP0001324_abnormal_eye_pigmentation0.85879021
115MP0002653_abnormal_ependyma_morphology0.85514780
116MP0005195_abnormal_posterior_eye0.85492938
117MP0002277_abnormal_respiratory_mucosa0.85065529
118MP0002138_abnormal_hepatobiliary_system0.84918180
119MP0002019_abnormal_tumor_incidence0.84785299
120MP0003646_muscle_fatigue0.84743042
121MP0002272_abnormal_nervous_system0.84569635
122MP0001529_abnormal_vocalization0.83632606
123MP0009333_abnormal_splenocyte_physiolog0.83170805
124MP0008260_abnormal_autophagy0.82811934
125MP0003186_abnormal_redox_activity0.82530437
126MP0001672_abnormal_embryogenesis/_devel0.82217593
127MP0005380_embryogenesis_phenotype0.82217593
128MP0002233_abnormal_nose_morphology0.81708559
129MP0001835_abnormal_antigen_presentation0.81694270
130MP0000639_abnormal_adrenal_gland0.81475176
131MP0008875_abnormal_xenobiotic_pharmacok0.81341912
132MP0004145_abnormal_muscle_electrophysio0.81325504
133MP0010678_abnormal_skin_adnexa0.79316359
134MP0002693_abnormal_pancreas_physiology0.78083041
135MP0001145_abnormal_male_reproductive0.77901034
136MP0003699_abnormal_female_reproductive0.77292923
137MP0003984_embryonic_growth_retardation0.77084092
138MP0002075_abnormal_coat/hair_pigmentati0.76240168
139MP0004043_abnormal_pH_regulation0.75637637
140MP0002398_abnormal_bone_marrow0.75031429
141MP0002085_abnormal_embryonic_tissue0.74572408
142MP0002088_abnormal_embryonic_growth/wei0.74217096
143MP0001944_abnormal_pancreas_morphology0.74083848
144MP0003941_abnormal_skin_development0.72817770
145MP0001545_abnormal_hematopoietic_system0.70667290
146MP0005397_hematopoietic_system_phenotyp0.70667290
147MP0002080_prenatal_lethality0.69066805
148MP0000703_abnormal_thymus_morphology0.67479458
149MP0005671_abnormal_response_to0.66874796
150MP0005220_abnormal_exocrine_pancreas0.66558164
151MP0005395_other_phenotype0.65686698
152MP0005408_hypopigmentation0.65627808

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.26709932
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.07546434
3Pancreatic fibrosis (HP:0100732)3.82443037
4Birth length less than 3rd percentile (HP:0003561)3.79470558
5True hermaphroditism (HP:0010459)3.74122602
6Aplastic anemia (HP:0001915)3.63044041
7Abnormality of chromosome stability (HP:0003220)3.53866785
8Abnormality of the preputium (HP:0100587)3.42739081
9Meckel diverticulum (HP:0002245)3.36127002
10Pancreatic cysts (HP:0001737)3.34955781
11Aplasia/Hypoplasia of the uvula (HP:0010293)3.26621007
12Type I transferrin isoform profile (HP:0003642)3.24947374
13Abnormality of the ileum (HP:0001549)3.22808286
14Abnormality of midbrain morphology (HP:0002418)3.20266874
15Molar tooth sign on MRI (HP:0002419)3.20266874
16Acute necrotizing encephalopathy (HP:0006965)3.15493122
17Acute encephalopathy (HP:0006846)3.01985287
18Nephronophthisis (HP:0000090)2.92124995
19Increased CSF lactate (HP:0002490)2.91608223
20Progressive macrocephaly (HP:0004481)2.90214636
21Methylmalonic acidemia (HP:0002912)2.88077773
22Mitochondrial inheritance (HP:0001427)2.82972817
23Medial flaring of the eyebrow (HP:0010747)2.82734722
24Colon cancer (HP:0003003)2.82541485
25Abnormality of the renal cortex (HP:0011035)2.82043247
26Abnormality of the labia minora (HP:0012880)2.81426365
27Nephrogenic diabetes insipidus (HP:0009806)2.70595181
28Congenital primary aphakia (HP:0007707)2.70575486
29Myelodysplasia (HP:0002863)2.68664828
30Small intestinal stenosis (HP:0012848)2.65753508
31Duodenal stenosis (HP:0100867)2.65753508
32Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.61987703
33Abnormality of alanine metabolism (HP:0010916)2.61987703
34Hyperalaninemia (HP:0003348)2.61987703
35Bone marrow hypocellularity (HP:0005528)2.61763580
36Abnormality of the renal medulla (HP:0100957)2.61092132
37Lipid accumulation in hepatocytes (HP:0006561)2.60400534
38Clubbing of toes (HP:0100760)2.59582407
39Abnormal mitochondria in muscle tissue (HP:0008316)2.59292300
403-Methylglutaconic aciduria (HP:0003535)2.55085045
41Hepatocellular necrosis (HP:0001404)2.54651970
42Hyperglycinemia (HP:0002154)2.54322161
4311 pairs of ribs (HP:0000878)2.52165850
44Hepatic necrosis (HP:0002605)2.50899564
45Gait imbalance (HP:0002141)2.48175869
46Congenital, generalized hypertrichosis (HP:0004540)2.47520032
47Methylmalonic aciduria (HP:0012120)2.46102835
48Lip pit (HP:0100267)2.43168117
49Absent rod-and cone-mediated responses on ERG (HP:0007688)2.41081221
50Abnormality of DNA repair (HP:0003254)2.39990171
51Abnormality of the anterior horn cell (HP:0006802)2.37336158
52Degeneration of anterior horn cells (HP:0002398)2.37336158
53Aplasia/Hypoplasia of the tongue (HP:0010295)2.35955483
54Sloping forehead (HP:0000340)2.34018558
55Microvesicular hepatic steatosis (HP:0001414)2.33784030
56Poor coordination (HP:0002370)2.28395798
57Abnormal rod and cone electroretinograms (HP:0008323)2.28011866
58Abnormality of the duodenum (HP:0002246)2.26473566
59Cerebral edema (HP:0002181)2.25660049
60Male pseudohermaphroditism (HP:0000037)2.24770198
61Abnormal biliary tract physiology (HP:0012439)2.24728435
62Bile duct proliferation (HP:0001408)2.24728435
63Aplasia/Hypoplasia of the tibia (HP:0005772)2.24415424
64Abnormality of the renal collecting system (HP:0004742)2.24018002
65Chronic hepatic failure (HP:0100626)2.23269116
66Occipital encephalocele (HP:0002085)2.22862807
67Papillary thyroid carcinoma (HP:0002895)2.22451070
68Hyperglycinuria (HP:0003108)2.22224159
69Optic nerve coloboma (HP:0000588)2.22166077
70Abnormality of serum amino acid levels (HP:0003112)2.18322640
71Median cleft lip (HP:0000161)2.16768752
72Abnormal protein N-linked glycosylation (HP:0012347)2.12783925
73Abnormal protein glycosylation (HP:0012346)2.12783925
74Abnormal glycosylation (HP:0012345)2.12783925
75Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.12783925
76Cystic liver disease (HP:0006706)2.11625351
77Abolished electroretinogram (ERG) (HP:0000550)2.11316152
78Aplasia/hypoplasia of the uterus (HP:0008684)2.11233507
79Abnormality of serine family amino acid metabolism (HP:0010894)2.10651698
80Abnormality of glycine metabolism (HP:0010895)2.10651698
81Abnormal lung lobation (HP:0002101)2.09838970
82Breast hypoplasia (HP:0003187)2.08623798
83Aganglionic megacolon (HP:0002251)2.07945102
84Abnormal hair whorl (HP:0010721)2.05777874
85Increased serum lactate (HP:0002151)2.05484325
86Abnormality of vitamin B metabolism (HP:0004340)2.04918285
87Supernumerary spleens (HP:0009799)2.03912780
88Sclerocornea (HP:0000647)2.03565071
89Preaxial hand polydactyly (HP:0001177)2.03151622
90Agnosia (HP:0010524)2.02837779
91Impulsivity (HP:0100710)2.02091115
92Patellar aplasia (HP:0006443)2.01630474
93Gaze-evoked nystagmus (HP:0000640)2.01259155
94Ectopic kidney (HP:0000086)1.98416914
95Congenital hepatic fibrosis (HP:0002612)1.97980590
96Pancreatic islet-cell hyperplasia (HP:0004510)1.97293554
97Congenital stationary night blindness (HP:0007642)1.96600952
98Acute myeloid leukemia (HP:0004808)1.96283967
99Lactic acidosis (HP:0003128)1.95479416
100Premature graying of hair (HP:0002216)1.94459087
101Abnormality of the carotid arteries (HP:0005344)1.94335058
102Abnormality of aspartate family amino acid metabolism (HP:0010899)1.94107698
103Medulloblastoma (HP:0002885)1.93233707
104Hypergonadotropic hypogonadism (HP:0000815)1.92721609
105Oligohydramnios (HP:0001562)1.92544422
106Absent thumb (HP:0009777)1.92139509
107Short tibia (HP:0005736)1.90958056
108Genital tract atresia (HP:0001827)1.90664675
109Aplasia/Hypoplasia of the patella (HP:0006498)1.90339890
110Exertional dyspnea (HP:0002875)1.89017316
111Abnormality of the columella (HP:0009929)1.88545961
112Hypothermia (HP:0002045)1.87451221
113Tubulointerstitial nephritis (HP:0001970)1.86448916
114Furrowed tongue (HP:0000221)1.85038221
115Lethargy (HP:0001254)1.84878508
116Renal cortical cysts (HP:0000803)1.84285878
117Vaginal atresia (HP:0000148)1.84093543
118Abnormality of methionine metabolism (HP:0010901)1.84037597
119Optic disc pallor (HP:0000543)1.83431745
120Facial cleft (HP:0002006)1.82813588
121Respiratory failure (HP:0002878)1.82296681
122Hypoglycemic coma (HP:0001325)1.82025344
123Postaxial hand polydactyly (HP:0001162)1.82023210
124Intestinal atresia (HP:0011100)1.80522301
125Postaxial foot polydactyly (HP:0001830)1.80417738
126Flat capital femoral epiphysis (HP:0003370)1.79833363
127Reticulocytopenia (HP:0001896)1.79495559
128Increased hepatocellular lipid droplets (HP:0006565)1.79370492
129Type 2 muscle fiber atrophy (HP:0003554)1.78619699
130Small hand (HP:0200055)1.78239723
131Tubular atrophy (HP:0000092)1.76954563
132Progressive inability to walk (HP:0002505)1.76571349
133Severe visual impairment (HP:0001141)1.76386522
134Triphalangeal thumb (HP:0001199)1.76072208
135Abnormality of the vitamin B12 metabolism (HP:0004341)1.75558318
136Reduced antithrombin III activity (HP:0001976)1.73936351
137Nephroblastoma (Wilms tumor) (HP:0002667)1.73725545
138Hypoplasia of the fovea (HP:0007750)1.73264242
139Aplasia/Hypoplasia of the fovea (HP:0008060)1.73264242
140Gastrointestinal atresia (HP:0002589)1.72885030
141Septo-optic dysplasia (HP:0100842)1.72875410
142Thrombocytosis (HP:0001894)1.72763541
143Abnormal spermatogenesis (HP:0008669)1.71307760
144Attenuation of retinal blood vessels (HP:0007843)1.70400395
145Bifid tongue (HP:0010297)1.70014573
146Chorioretinal coloboma (HP:0000567)1.68963762
147Broad foot (HP:0001769)1.66724420
148Microretrognathia (HP:0000308)1.66139145
149Astigmatism (HP:0000483)1.66015345
150Stenosis of the external auditory canal (HP:0000402)1.65905028
151Volvulus (HP:0002580)1.65519934
152Abnormality of the fovea (HP:0000493)1.64565794
153Secondary amenorrhea (HP:0000869)1.63829625
154Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.63738343
155Short thumb (HP:0009778)1.62460958
156Embryonal renal neoplasm (HP:0011794)1.60864528
157Anencephaly (HP:0002323)1.60544772

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.78627124
2BUB13.05120530
3CDC73.02405435
4SRPK12.95353617
5PLK42.82007652
6WNK32.74469670
7ACVR1B2.52633779
8VRK12.38679249
9MST42.35606757
10BRSK22.33402428
11MAP4K22.30942203
12CDK82.19036611
13MKNK22.18211976
14BRAF2.15417459
15TRIM282.14983691
16STK162.12287890
17WEE12.07088274
18PASK2.04443533
19EIF2AK12.02056922
20GRK12.00071399
21SIK31.99838482
22TSSK61.98252946
23MKNK11.93767588
24TTK1.85977395
25TAOK21.82186535
26BMPR21.78447260
27ZAK1.75905005
28CCNB11.70633973
29PLK31.65840179
30EIF2AK31.62722944
31PLK11.55126056
32VRK21.53031357
33TAOK31.52320447
34CASK1.52293864
35INSRR1.52126723
36AKT31.51122292
37MAP3K61.47784004
38MUSK1.46591426
39PBK1.46365390
40ATR1.44277084
41IRAK31.42038249
42NUAK11.41558078
43MAP3K41.39797729
44NEK11.39702676
45STK38L1.39554561
46IRAK41.38363319
47RPS6KA41.32090284
48CHEK21.28437515
49PINK11.27428754
50CSNK1G11.26534277
51ADRBK21.25346914
52OXSR11.22511950
53AURKB1.22167110
54MAPK131.20164737
55TEC1.16357873
56STK391.16126267
57CDK31.15707530
58CAMKK21.13393548
59MAP2K71.11260864
60CSNK1G21.09846268
61CSNK1G31.08031821
62BCKDK1.05878044
63PAK31.05732651
64YES11.05453543
65NEK61.03702408
66WNK41.02180657
67CDK71.00372858
68BMPR1B1.00151046
69NLK1.00104107
70TNIK0.98923610
71BRSK10.97454236
72MAP3K120.96515178
73ERBB30.96041781
74TLK10.94381009
75BCR0.93151630
76PDK20.92677766
77CSNK1A1L0.91743291
78PHKG20.91352708
79PHKG10.91352708
80NME10.90619795
81PRKCE0.89776165
82PNCK0.87366889
83BRD40.86350759
84DYRK20.86132695
85NEK20.85810580
86TGFBR10.85249164
87TXK0.84420675
88CHEK10.82772916
89ARAF0.82142645
90AURKA0.81230218
91FGFR20.79842773
92ATM0.79624493
93KIT0.73814072
94PLK20.73181502
95TAF10.72548433
96STK100.72087634
97CDK190.71400497
98FLT30.70878589
99OBSCN0.70192429
100PIM20.67717669
101MAP3K50.67389528
102RPS6KB20.66696427
103SGK20.64938206
104EIF2AK20.64630443
105CDK90.63840811
106MAP2K30.63721897
107STK240.61421699
108MAP3K80.60744626
109FER0.58431179
110PRKCG0.58419327
111CSNK2A10.57270458
112MAP3K30.53789886
113CDK20.52569133
114ADRBK10.51797603
115MELK0.50774376
116MAPKAPK50.49276878
117RPS6KB10.48715655
118MAP3K130.48219540
119DYRK30.44968942
120CDK10.43883724
121MOS0.43743507
122STK30.42913502
123MAP2K60.42707632
124CSNK2A20.41951285
125RPS6KA50.41893341
126CDK40.39925108
127CSNK1A10.39377006
128JAK30.38738152
129IRAK10.38679258
130FGFR10.38218655
131EPHA40.37785501
132RAF10.37441477
133NME20.35244233
134TIE10.35159696
135TAOK10.34879277
136TRPM70.33841594
137BTK0.33749922
138CAMK2A0.33697547
139PRPF4B0.33278352
140STK40.32476855
141CHUK0.32019703
142PRKACB0.31760358
143MAP3K140.31600935
144PRKACA0.31180344
145LATS10.30709519
146CSNK1D0.30438676
147PTK2B0.29675450
148LYN0.29056798

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034303.87834899
2Homologous recombination_Homo sapiens_hsa034403.53440561
3DNA replication_Homo sapiens_hsa030303.51436164
4RNA polymerase_Homo sapiens_hsa030203.41225003
5Protein export_Homo sapiens_hsa030603.14191853
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.01345847
7Proteasome_Homo sapiens_hsa030502.94425970
8Propanoate metabolism_Homo sapiens_hsa006402.75670511
9Fanconi anemia pathway_Homo sapiens_hsa034602.71897073
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.71040620
11Cell cycle_Homo sapiens_hsa041102.57863693
12Non-homologous end-joining_Homo sapiens_hsa034502.53545355
13Base excision repair_Homo sapiens_hsa034102.51039245
14RNA degradation_Homo sapiens_hsa030182.49268207
15Nucleotide excision repair_Homo sapiens_hsa034202.48615932
16Spliceosome_Homo sapiens_hsa030402.41245538
17RNA transport_Homo sapiens_hsa030132.31892531
18Pyrimidine metabolism_Homo sapiens_hsa002402.31871816
19Basal transcription factors_Homo sapiens_hsa030222.29920366
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.26718776
21Butanoate metabolism_Homo sapiens_hsa006502.10685840
22Ribosome_Homo sapiens_hsa030101.97534703
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.84997484
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.77769102
25Selenocompound metabolism_Homo sapiens_hsa004501.74418232
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.68821961
27Purine metabolism_Homo sapiens_hsa002301.59965602
28Fatty acid elongation_Homo sapiens_hsa000621.46747525
29Tryptophan metabolism_Homo sapiens_hsa003801.35624347
30Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.31766716
31Steroid biosynthesis_Homo sapiens_hsa001001.30652171
32Nitrogen metabolism_Homo sapiens_hsa009101.30555754
33Primary bile acid biosynthesis_Homo sapiens_hsa001201.29850783
34Peroxisome_Homo sapiens_hsa041461.26913660
35Maturity onset diabetes of the young_Homo sapiens_hsa049501.24726429
36p53 signaling pathway_Homo sapiens_hsa041151.21911211
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.21712354
38Epstein-Barr virus infection_Homo sapiens_hsa051691.17210234
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.16248768
40Other glycan degradation_Homo sapiens_hsa005111.14859618
41Pyruvate metabolism_Homo sapiens_hsa006201.14727141
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.10953154
43SNARE interactions in vesicular transport_Homo sapiens_hsa041301.04823446
44mRNA surveillance pathway_Homo sapiens_hsa030151.03988378
45Linoleic acid metabolism_Homo sapiens_hsa005911.03536314
46N-Glycan biosynthesis_Homo sapiens_hsa005101.03135990
47One carbon pool by folate_Homo sapiens_hsa006701.01767920
48beta-Alanine metabolism_Homo sapiens_hsa004101.01180528
49Caffeine metabolism_Homo sapiens_hsa002320.99366826
50Circadian rhythm_Homo sapiens_hsa047100.97990098
51Glutathione metabolism_Homo sapiens_hsa004800.94076756
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.93719766
53Herpes simplex infection_Homo sapiens_hsa051680.92222467
54Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90096055
55Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.86450655
56Chemical carcinogenesis_Homo sapiens_hsa052040.85991146
57Fatty acid degradation_Homo sapiens_hsa000710.82931828
58Ether lipid metabolism_Homo sapiens_hsa005650.81507627
59Huntingtons disease_Homo sapiens_hsa050160.80996987
60Steroid hormone biosynthesis_Homo sapiens_hsa001400.79836789
61Retinol metabolism_Homo sapiens_hsa008300.79668859
62Fatty acid metabolism_Homo sapiens_hsa012120.79054188
63Pentose and glucuronate interconversions_Homo sapiens_hsa000400.78766807
64Vitamin B6 metabolism_Homo sapiens_hsa007500.78263427
65alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.77759705
66Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77714921
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.75952241
68Antigen processing and presentation_Homo sapiens_hsa046120.73268563
69Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.72173737
70Folate biosynthesis_Homo sapiens_hsa007900.71672417
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70890700
72Oocyte meiosis_Homo sapiens_hsa041140.70515910
73Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68835462
74Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.68319067
75Nicotine addiction_Homo sapiens_hsa050330.68127050
76Type I diabetes mellitus_Homo sapiens_hsa049400.66712543
77Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.66422163
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.66348672
79Oxidative phosphorylation_Homo sapiens_hsa001900.65969046
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64751570
81Regulation of autophagy_Homo sapiens_hsa041400.63926743
82Parkinsons disease_Homo sapiens_hsa050120.62710477
83Cardiac muscle contraction_Homo sapiens_hsa042600.62252657
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61473354
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57044298
86Vitamin digestion and absorption_Homo sapiens_hsa049770.56113640
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55962638
88TGF-beta signaling pathway_Homo sapiens_hsa043500.55762074
89Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55143722
90HTLV-I infection_Homo sapiens_hsa051660.54887162
91Vibrio cholerae infection_Homo sapiens_hsa051100.54038106
92Taste transduction_Homo sapiens_hsa047420.54023593
93Thyroid cancer_Homo sapiens_hsa052160.53357723
94Hematopoietic cell lineage_Homo sapiens_hsa046400.51369272
95Sphingolipid metabolism_Homo sapiens_hsa006000.50521482
96Rheumatoid arthritis_Homo sapiens_hsa053230.49514873
97NF-kappa B signaling pathway_Homo sapiens_hsa040640.46058254
98Measles_Homo sapiens_hsa051620.45995669
99Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.45868507
100Arachidonic acid metabolism_Homo sapiens_hsa005900.45866537
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45629328
102Phototransduction_Homo sapiens_hsa047440.45072812
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.44998171
104Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44216428
105ABC transporters_Homo sapiens_hsa020100.43601837
106Allograft rejection_Homo sapiens_hsa053300.41688659
107Viral carcinogenesis_Homo sapiens_hsa052030.41263223
108Hepatitis B_Homo sapiens_hsa051610.40686519
109Arginine and proline metabolism_Homo sapiens_hsa003300.40336429
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40249041
111Influenza A_Homo sapiens_hsa051640.39213747
112NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38531746
113Fat digestion and absorption_Homo sapiens_hsa049750.37741813
114Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36341998
115Carbon metabolism_Homo sapiens_hsa012000.35897356
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35406023
117Cysteine and methionine metabolism_Homo sapiens_hsa002700.34378231
118Shigellosis_Homo sapiens_hsa051310.34207102
119Glycosaminoglycan degradation_Homo sapiens_hsa005310.33519860
120Colorectal cancer_Homo sapiens_hsa052100.31420091
121Galactose metabolism_Homo sapiens_hsa000520.31014690
122Lysine degradation_Homo sapiens_hsa003100.30950819
123Drug metabolism - other enzymes_Homo sapiens_hsa009830.29858888
124Serotonergic synapse_Homo sapiens_hsa047260.29702477
125Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28691939
126Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.26106260
127Primary immunodeficiency_Homo sapiens_hsa053400.26069386
128FoxO signaling pathway_Homo sapiens_hsa040680.25675088
129Legionellosis_Homo sapiens_hsa051340.25280118
130Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.24788171
131Insulin secretion_Homo sapiens_hsa049110.22710714
132Alcoholism_Homo sapiens_hsa050340.22587260
133Alzheimers disease_Homo sapiens_hsa050100.22189898
134Collecting duct acid secretion_Homo sapiens_hsa049660.22073104
135Wnt signaling pathway_Homo sapiens_hsa043100.21211928
136Leishmaniasis_Homo sapiens_hsa051400.21019227
137Pancreatic cancer_Homo sapiens_hsa052120.21016489
138Ovarian steroidogenesis_Homo sapiens_hsa049130.20191926
139Toll-like receptor signaling pathway_Homo sapiens_hsa046200.19658033
140TNF signaling pathway_Homo sapiens_hsa046680.19645740
141Notch signaling pathway_Homo sapiens_hsa043300.17748359
142Asthma_Homo sapiens_hsa053100.17717778
143Sulfur metabolism_Homo sapiens_hsa009200.17611562
144MicroRNAs in cancer_Homo sapiens_hsa052060.17310776
145Olfactory transduction_Homo sapiens_hsa047400.17093435
146Intestinal immune network for IgA production_Homo sapiens_hsa046720.16881800
147Phagosome_Homo sapiens_hsa041450.16559187
148Sulfur relay system_Homo sapiens_hsa041220.16412530
149Jak-STAT signaling pathway_Homo sapiens_hsa046300.15235525
150Metabolic pathways_Homo sapiens_hsa011000.15226684

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