DPM3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.20059019
2ribosomal small subunit biogenesis (GO:0042274)7.07686416
3viral transcription (GO:0019083)6.94590336
4translational termination (GO:0006415)6.62468175
5cotranslational protein targeting to membrane (GO:0006613)6.58793345
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.53613050
7protein targeting to ER (GO:0045047)6.48216352
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.31025799
9protein localization to endoplasmic reticulum (GO:0070972)6.21080622
10establishment of protein localization to endoplasmic reticulum (GO:0072599)6.18369871
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)6.10965404
12ATP synthesis coupled proton transport (GO:0015986)6.08852974
13energy coupled proton transport, down electrochemical gradient (GO:0015985)6.08852974
14translational elongation (GO:0006414)5.38234686
15respiratory electron transport chain (GO:0022904)5.30938054
16viral life cycle (GO:0019058)5.18839228
17electron transport chain (GO:0022900)5.18787972
18cellular protein complex disassembly (GO:0043624)5.05375387
19protein complex biogenesis (GO:0070271)4.92671632
20mitochondrial respiratory chain complex I assembly (GO:0032981)4.77039498
21NADH dehydrogenase complex assembly (GO:0010257)4.77039498
22mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.77039498
23nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.64103418
24GTP biosynthetic process (GO:0006183)4.51410699
25protein neddylation (GO:0045116)4.49097793
26mitochondrial respiratory chain complex assembly (GO:0033108)4.40158261
27maturation of SSU-rRNA (GO:0030490)4.39427609
28DNA deamination (GO:0045006)4.38072274
29chaperone-mediated protein transport (GO:0072321)4.32900311
30translational initiation (GO:0006413)4.29254832
31signal peptide processing (GO:0006465)4.28951033
32protein targeting to membrane (GO:0006612)4.28386303
33respiratory chain complex IV assembly (GO:0008535)4.27862522
34translation (GO:0006412)4.24295244
35protein complex disassembly (GO:0043241)4.15897182
36central nervous system myelination (GO:0022010)4.04863569
37axon ensheathment in central nervous system (GO:0032291)4.04863569
38ribosomal large subunit biogenesis (GO:0042273)4.04319289
39macromolecular complex disassembly (GO:0032984)3.94584302
40proteasome assembly (GO:0043248)3.94207956
41transcription elongation from RNA polymerase III promoter (GO:0006385)3.92959655
42termination of RNA polymerase III transcription (GO:0006386)3.92959655
43oxidative phosphorylation (GO:0006119)3.91929874
44cytochrome complex assembly (GO:0017004)3.82973824
45UTP biosynthetic process (GO:0006228)3.71780786
46fatty acid elongation (GO:0030497)3.60682974
47CTP metabolic process (GO:0046036)3.54811095
48CTP biosynthetic process (GO:0006241)3.54811095
49pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.54356017
50guanosine-containing compound biosynthetic process (GO:1901070)3.43313824
51protein localization to mitochondrion (GO:0070585)3.36324775
52aldehyde catabolic process (GO:0046185)3.34261833
53inner mitochondrial membrane organization (GO:0007007)3.33655057
54nucleoside triphosphate biosynthetic process (GO:0009142)3.31950572
55regulation of mitochondrial translation (GO:0070129)3.29801608
56L-phenylalanine catabolic process (GO:0006559)3.28484611
57erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.28484611
58purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.27223962
59* mannosylation (GO:0097502)3.25263766
60mitochondrial transport (GO:0006839)3.25162776
61deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.24988830
62rRNA modification (GO:0000154)3.24424279
63nuclear-transcribed mRNA catabolic process (GO:0000956)3.24279925
64peptidyl-histidine modification (GO:0018202)3.23159597
65intracellular protein transmembrane import (GO:0044743)3.22997044
66L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.22844426
67tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.22359939
68RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.22359939
69water-soluble vitamin biosynthetic process (GO:0042364)3.22166171
70UTP metabolic process (GO:0046051)3.22001529
71purine nucleoside triphosphate biosynthetic process (GO:0009145)3.21292567
72cellular component biogenesis (GO:0044085)3.19215317
73* GPI anchor biosynthetic process (GO:0006506)3.15520484
74hydrogen ion transmembrane transport (GO:1902600)3.13557677
75establishment of protein localization to membrane (GO:0090150)3.08240208
76establishment of protein localization to mitochondrial membrane (GO:0090151)3.07883292
77mRNA catabolic process (GO:0006402)3.07730422
78L-phenylalanine metabolic process (GO:0006558)3.07384604
79erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.07384604
80protein targeting to mitochondrion (GO:0006626)3.03459248
817-methylguanosine RNA capping (GO:0009452)3.03322355
82RNA capping (GO:0036260)3.03322355
83pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.02855799
84protein targeting (GO:0006605)3.00665682
85platelet dense granule organization (GO:0060155)3.00631175
86deoxyribonucleotide catabolic process (GO:0009264)2.99428840
877-methylguanosine mRNA capping (GO:0006370)2.98759709
88ribonucleoprotein complex biogenesis (GO:0022613)2.95452212
89ribonucleoside triphosphate biosynthetic process (GO:0009201)2.95076166
90cellular ketone body metabolic process (GO:0046950)2.93264376
91pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.92625637
92ATP biosynthetic process (GO:0006754)2.91742038
93nucleotide transmembrane transport (GO:1901679)2.90412096
94antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.89181547
95preassembly of GPI anchor in ER membrane (GO:0016254)2.88071483
96proton transport (GO:0015992)2.87158706
97pseudouridine synthesis (GO:0001522)2.84905695
98pyrimidine nucleotide catabolic process (GO:0006244)2.83464839
99deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.83238641
100sequestering of actin monomers (GO:0042989)2.82731045
101long-chain fatty acid biosynthetic process (GO:0042759)2.81526388
102amyloid precursor protein metabolic process (GO:0042982)2.81408876
103iron-sulfur cluster assembly (GO:0016226)2.80856086
104metallo-sulfur cluster assembly (GO:0031163)2.80856086
105DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.80131560
106deoxyribose phosphate catabolic process (GO:0046386)2.79859811
107positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.78966233
108establishment of protein localization to mitochondrion (GO:0072655)2.78910218
109hydrogen transport (GO:0006818)2.78759770
110nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.78638822
111purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.77858591
112purine nucleoside monophosphate biosynthetic process (GO:0009127)2.77858591
113base-excision repair, AP site formation (GO:0006285)2.77222937
114amyloid precursor protein catabolic process (GO:0042987)2.76858192
115positive regulation of TOR signaling (GO:0032008)2.72614844
116* GPI anchor metabolic process (GO:0006505)2.72201790
117negative regulation of ligase activity (GO:0051352)2.71815882
118pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.70265929
119antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.70098251
120pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.69829168
121positive regulation of cellular amine metabolic process (GO:0033240)2.69222614
122GDP-mannose metabolic process (GO:0019673)2.68271300
123viral protein processing (GO:0019082)2.67471130
124RNA catabolic process (GO:0006401)2.67390778
125negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.66505763
126establishment of viral latency (GO:0019043)2.66359446
127aerobic respiration (GO:0009060)2.65942208
128exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.62696445
129regulation of cellular amino acid metabolic process (GO:0006521)2.58976455
130establishment of protein localization to organelle (GO:0072594)2.56789585

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat7.52385616
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.77106455
3* GABP_17652178_ChIP-ChIP_JURKAT_Human4.30713581
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.95152511
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.87911843
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.59819982
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.31260393
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.17933145
9* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.16038530
10ELF1_17652178_ChIP-ChIP_JURKAT_Human3.15287928
11* ETS1_20019798_ChIP-Seq_JURKAT_Human3.04301030
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.85621455
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.79103465
14PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.69079921
15* SRF_21415370_ChIP-Seq_HL-1_Mouse2.55408508
16CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.52963323
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.47679093
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.38201099
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.37977137
20* VDR_23849224_ChIP-Seq_CD4+_Human2.26717996
21MYC_18358816_ChIP-ChIP_MESCs_Mouse2.14027757
22ELK1_19687146_ChIP-ChIP_HELA_Human2.06092411
23FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.98437018
24* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.94863262
25FOXP3_21729870_ChIP-Seq_TREG_Human1.91421330
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.88520534
27BP1_19119308_ChIP-ChIP_Hs578T_Human1.86814213
28DCP1A_22483619_ChIP-Seq_HELA_Human1.85547858
29THAP11_20581084_ChIP-Seq_MESCs_Mouse1.81031276
30HOXB4_20404135_ChIP-ChIP_EML_Mouse1.80759335
31IRF1_19129219_ChIP-ChIP_H3396_Human1.79654356
32LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.76098572
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.74928037
34ELK1_22589737_ChIP-Seq_MCF10A_Human1.74716372
35* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.73838992
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.70497835
37XRN2_22483619_ChIP-Seq_HELA_Human1.67353012
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.64061872
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63969564
40TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62316983
41IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.61551902
42TTF2_22483619_ChIP-Seq_HELA_Human1.59388994
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.54049720
44SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.52020127
45MYC_19030024_ChIP-ChIP_MESCs_Mouse1.51294972
46MYC_19079543_ChIP-ChIP_MESCs_Mouse1.42577521
47CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.34207687
48* KDM5A_27292631_Chip-Seq_BREAST_Human1.33229515
49IRF8_22096565_ChIP-ChIP_GC-B_Human1.26125419
50* GABP_19822575_ChIP-Seq_HepG2_Human1.22716320
51PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.22157172
52VDR_22108803_ChIP-Seq_LS180_Human1.18459967
53ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.18120776
54MYC_18940864_ChIP-ChIP_HL60_Human1.17462789
55PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.16699854
56TAF15_26573619_Chip-Seq_HEK293_Human1.16657803
57PADI4_21655091_ChIP-ChIP_MCF-7_Human1.15266485
58CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14961836
59RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.14890870
60ZNF274_21170338_ChIP-Seq_K562_Hela1.14347300
61TP53_22573176_ChIP-Seq_HFKS_Human1.14183274
62PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.12525889
63CTCF_18555785_ChIP-Seq_MESCs_Mouse1.10828966
64FOXP1_21924763_ChIP-Seq_HESCs_Human1.09480910
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08700013
66SPI1_23547873_ChIP-Seq_NB4_Human1.08238327
67ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06360810
68SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.06061288
69BMI1_23680149_ChIP-Seq_NPCS_Mouse1.05745210
70MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.04256279
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03910728
72EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03908407
73SCL_19346495_ChIP-Seq_HPC-7_Human1.01879173
74SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.00755887
75ELF1_20517297_ChIP-Seq_JURKAT_Human1.00516820
76STAT1_20625510_ChIP-Seq_HELA_Human0.97954492
77CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97808406
78* TAF2_19829295_ChIP-Seq_ESCs_Human0.97168111
79CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96746537
80RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.96094324
81FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.95005283
82STAT4_19710469_ChIP-ChIP_TH1__Mouse0.93389511
83FOXA1_27270436_Chip-Seq_PROSTATE_Human0.92851593
84FOXA1_25329375_ChIP-Seq_VCAP_Human0.92851593
85BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92667062
86CTCF_26484167_Chip-Seq_Bcells_Mouse0.91340290
87YY1_22570637_ChIP-Seq_MALME-3M_Human0.91184100
88MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.91078095
89CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.91039633
90E2F4_17652178_ChIP-ChIP_JURKAT_Human0.90777212
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89396577
92FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.89380422
93LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.89201124
94BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.89142061
95BCL6_27268052_Chip-Seq_Bcells_Human0.88508181
96IRF8_21731497_ChIP-ChIP_J774_Mouse0.87812923
97NANOG_20526341_ChIP-Seq_ESCs_Human0.86124887
98HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.85994740
99NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.85427652
100POU5F1_16153702_ChIP-ChIP_HESCs_Human0.84849607
101PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.84778995
102NCOR_22424771_ChIP-Seq_293T_Human0.84478218
103ZFP57_27257070_Chip-Seq_ESCs_Mouse0.83827989
104CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.83339766
105MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.83276534
106IGF1R_20145208_ChIP-Seq_DFB_Human0.83088175
107GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.82664235
108GATA3_21878914_ChIP-Seq_MCF-7_Human0.81394885
109EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.81323913
110YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.79679700
111HTT_18923047_ChIP-ChIP_STHdh_Human0.79238672
112ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.79134448
113E2F1_20622854_ChIP-Seq_HELA_Human0.78964745
114PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.77917123
115* ERA_21632823_ChIP-Seq_H3396_Human0.77735763
116AR_20517297_ChIP-Seq_VCAP_Human0.77297752
117NELFA_20434984_ChIP-Seq_ESCs_Mouse0.77241746
118* SRY_22984422_ChIP-ChIP_TESTIS_Rat0.77136074
119SOX17_20123909_ChIP-Seq_XEN_Mouse0.76360727
120TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.75751454
121FUS_26573619_Chip-Seq_HEK293_Human0.74371396
122* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73972783
123RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.73567207
124MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.73271640
125EGR1_23403033_ChIP-Seq_LIVER_Mouse0.72942731
126KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.72821038
127POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.72767730
128* ETV2_25802403_ChIP-Seq_MESCs_Mouse0.72566131
129NOTCH1_21737748_ChIP-Seq_TLL_Human0.70556457
130POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.69850159
131ERG_20517297_ChIP-Seq_VCAP_Human0.69779704
132CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.69581494

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.40202732
2MP0003136_yellow_coat_color3.83823098
3MP0002837_dystrophic_cardiac_calcinosis3.64095052
4MP0004381_abnormal_hair_follicle2.79436702
5MP0001986_abnormal_taste_sensitivity2.62388698
6MP0001905_abnormal_dopamine_level2.57729892
7MP0001529_abnormal_vocalization2.55207897
8MP0005409_darkened_coat_color2.42082055
9MP0001188_hyperpigmentation2.36410480
10MP0000372_irregular_coat_pigmentation2.34280676
11MP0002148_abnormal_hypersensitivity_rea2.25460939
12MP0003724_increased_susceptibility_to2.22184903
13MP0005379_endocrine/exocrine_gland_phen2.21714927
14MP0002132_abnormal_respiratory_system2.19737084
15MP0000920_abnormal_myelination2.17172267
16MP0004142_abnormal_muscle_tone2.03589143
17MP0002638_abnormal_pupillary_reflex1.99691762
18MP0005075_abnormal_melanosome_morpholog1.98987973
19MP0003186_abnormal_redox_activity1.97868834
20MP0002938_white_spotting1.97401475
21MP0002139_abnormal_hepatobiliary_system1.89552099
22MP0009785_altered_susceptibility_to1.86556174
23MP0003011_delayed_dark_adaptation1.81013187
24MP0005332_abnormal_amino_acid1.80289037
25MP0008875_abnormal_xenobiotic_pharmacok1.76836519
26MP0002653_abnormal_ependyma_morphology1.70143472
27MP0003786_premature_aging1.68445676
28MP0005671_abnormal_response_to1.68185092
29MP0002909_abnormal_adrenal_gland1.68109136
30MP0001835_abnormal_antigen_presentation1.66761272
31MP0003880_abnormal_central_pattern1.65697174
32MP0005174_abnormal_tail_pigmentation1.62232485
33MP0006292_abnormal_olfactory_placode1.61185434
34MP0004019_abnormal_vitamin_homeostasis1.60456717
35MP0004147_increased_porphyrin_level1.59516304
36MP0005171_absent_coat_pigmentation1.57968162
37MP0002234_abnormal_pharynx_morphology1.52441200
38MP0010386_abnormal_urinary_bladder1.51170288
39MP0002163_abnormal_gland_morphology1.49468629
40MP0005000_abnormal_immune_tolerance1.47405727
41MP0005058_abnormal_lysosome_morphology1.46442890
42MP0005025_abnormal_response_to1.46081639
43MP0008058_abnormal_DNA_repair1.44782274
44MP0008789_abnormal_olfactory_epithelium1.42910401
45MP0001984_abnormal_olfaction1.42633992
46MP0001944_abnormal_pancreas_morphology1.42031194
47MP0002277_abnormal_respiratory_mucosa1.40306698
48MP0002693_abnormal_pancreas_physiology1.35614769
49MP0006036_abnormal_mitochondrial_physio1.34334802
50MP0006276_abnormal_autonomic_nervous1.32972663
51MP0003122_maternal_imprinting1.31822675
52MP0005408_hypopigmentation1.30412658
53MP0009046_muscle_twitch1.30333915
54MP0005451_abnormal_body_composition1.28402976
55MP0008872_abnormal_physiological_respon1.28224222
56MP0002095_abnormal_skin_pigmentation1.27052738
57MP0005084_abnormal_gallbladder_morpholo1.25546829
58MP0002102_abnormal_ear_morphology1.24270113
59MP0004133_heterotaxia1.23924677
60MP0003806_abnormal_nucleotide_metabolis1.23748763
61MP0005645_abnormal_hypothalamus_physiol1.23370702
62MP0005646_abnormal_pituitary_gland1.21961071
63MP0002419_abnormal_innate_immunity1.20190849
64MP0000465_gastrointestinal_hemorrhage1.16159053
65MP0006072_abnormal_retinal_apoptosis1.14907714
66MP0010030_abnormal_orbit_morphology1.14368386
67MP0009333_abnormal_splenocyte_physiolog1.14180164
68MP0001764_abnormal_homeostasis1.12177317
69MP0001790_abnormal_immune_system1.09899868
70MP0005387_immune_system_phenotype1.09899868
71MP0005365_abnormal_bile_salt1.09822167
72MP0001756_abnormal_urination1.09000145
73MP0003763_abnormal_thymus_physiology1.07334762
74MP0004782_abnormal_surfactant_physiolog1.07259856
75MP0002723_abnormal_immune_serum1.06476457
76MP0005220_abnormal_exocrine_pancreas1.04922119
77MP0000015_abnormal_ear_pigmentation1.04098644
78MP0003787_abnormal_imprinting1.02381678
79MP0001968_abnormal_touch/_nociception1.02147858
80MP0002876_abnormal_thyroid_physiology1.01160672
81MP0002420_abnormal_adaptive_immunity0.99464062
82MP0005389_reproductive_system_phenotype0.98812676
83MP0004742_abnormal_vestibular_system0.98767089
84MP0003950_abnormal_plasma_membrane0.97483726
85MP0005636_abnormal_mineral_homeostasis0.96832245
86MP0006082_CNS_inflammation0.96192027
87MP0001819_abnormal_immune_cell0.95971733
88MP0002160_abnormal_reproductive_system0.95808806
89MP0001542_abnormal_bone_strength0.95622684
90MP0003283_abnormal_digestive_organ0.94034835
91MP0002090_abnormal_vision0.93135007
92MP0003866_abnormal_defecation0.92852258
93MP0003718_maternal_effect0.92077706
94MP0001664_abnormal_digestion0.90378597
95MP0005551_abnormal_eye_electrophysiolog0.90252911
96MP0002452_abnormal_antigen_presenting0.90049114
97MP0000358_abnormal_cell_content/0.89985542
98MP0002078_abnormal_glucose_homeostasis0.89826807
99MP0002736_abnormal_nociception_after0.89699602
100MP0005423_abnormal_somatic_nervous0.89316569
101MP0003436_decreased_susceptibility_to0.89063162
102MP0001800_abnormal_humoral_immune0.88874165
103MP0009643_abnormal_urine_homeostasis0.87998867
104MP0000613_abnormal_salivary_gland0.86407067
105MP0009697_abnormal_copulation0.86376921
106MP0000631_abnormal_neuroendocrine_gland0.85836719
107MP0001919_abnormal_reproductive_system0.85443362
108MP0005360_urolithiasis0.85322525
109MP0002272_abnormal_nervous_system0.85320509
110MP0009745_abnormal_behavioral_response0.84588204
111MP0005253_abnormal_eye_physiology0.84531720
112MP0005410_abnormal_fertilization0.84373675
113MP0001851_eye_inflammation0.83936413
114MP0001324_abnormal_eye_pigmentation0.83393178
115MP0008877_abnormal_DNA_methylation0.82883903
116MP0005085_abnormal_gallbladder_physiolo0.82699226
117MP0002822_catalepsy0.81074700
118MP0002405_respiratory_system_inflammati0.81013061
119MP0010329_abnormal_lipoprotein_level0.80780226
120MP0005499_abnormal_olfactory_system0.79980562
121MP0005394_taste/olfaction_phenotype0.79980562
122MP0003315_abnormal_perineum_morphology0.79388454
123MP0002933_joint_inflammation0.79160261
124MP0005535_abnormal_body_temperature0.79141831
125MP0003137_abnormal_impulse_conducting0.79032938
126MP0000026_abnormal_inner_ear0.78248134
127MP0001293_anophthalmia0.77871419
128MP0000566_synostosis0.77779875
129MP0008469_abnormal_protein_level0.77396545
130MP0008057_abnormal_DNA_replication0.76992436
131MP0003690_abnormal_glial_cell0.76099652
132MP0003121_genomic_imprinting0.75741849
133MP0003123_paternal_imprinting0.75631069
134MP0005195_abnormal_posterior_eye0.74403601
135MP0005319_abnormal_enzyme/_coenzyme0.73987193
136MP0005266_abnormal_metabolism0.73549642
137MP0006035_abnormal_mitochondrial_morpho0.72960393
138MP0003953_abnormal_hormone_level0.72879030
139MP0003938_abnormal_ear_development0.72817630
140MP0000685_abnormal_immune_system0.72374186
141MP0002229_neurodegeneration0.71474579
142MP0005164_abnormal_response_to0.71335527
143MP0001845_abnormal_inflammatory_respons0.71331835
144MP0009765_abnormal_xenobiotic_induced0.71302430
145MP0008995_early_reproductive_senescence0.71269521
146MP0005464_abnormal_platelet_physiology0.71042272
147MP0003195_calcinosis0.70370138
148MP0000639_abnormal_adrenal_gland0.69353017
149MP0001963_abnormal_hearing_physiology0.69250726
150MP0001485_abnormal_pinna_reflex0.67352045
151MP0002295_abnormal_pulmonary_circulatio0.66704408
152MP0002557_abnormal_social/conspecific_i0.66654452
153MP0001853_heart_inflammation0.66359187
154MP0002928_abnormal_bile_duct0.66195113
155MP0001727_abnormal_embryo_implantation0.66193294

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.45230190
2Acute necrotizing encephalopathy (HP:0006965)5.44963518
3Mitochondrial inheritance (HP:0001427)5.40102468
4Abnormal number of erythroid precursors (HP:0012131)5.16580658
5Increased hepatocellular lipid droplets (HP:0006565)5.15822911
6Renal Fanconi syndrome (HP:0001994)5.03778654
7Abnormal mitochondria in muscle tissue (HP:0008316)4.83424723
8Hepatocellular necrosis (HP:0001404)4.77822220
9Lipid accumulation in hepatocytes (HP:0006561)4.59960404
10Acute encephalopathy (HP:0006846)4.49729349
11Progressive macrocephaly (HP:0004481)4.47501250
12Increased CSF lactate (HP:0002490)4.43853142
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.34735283
14Hepatic necrosis (HP:0002605)4.24282789
153-Methylglutaconic aciduria (HP:0003535)4.18543608
16Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.14503437
17Reticulocytopenia (HP:0001896)4.09207483
18Increased intramyocellular lipid droplets (HP:0012240)4.03503082
19Exertional dyspnea (HP:0002875)3.81163735
20Macrocytic anemia (HP:0001972)3.71623386
21Decreased activity of mitochondrial respiratory chain (HP:0008972)3.70156994
22Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.70156994
23Abnormality of renal resorption (HP:0011038)3.48935223
24Increased muscle lipid content (HP:0009058)3.42228331
25Parakeratosis (HP:0001036)3.37594694
26Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.32140701
27Pallor (HP:0000980)3.13883140
28Respiratory difficulties (HP:0002880)3.09620048
29Respiratory failure (HP:0002878)2.98088167
30Leukodystrophy (HP:0002415)2.97754303
31Increased serum lactate (HP:0002151)2.97114864
32Vacuolated lymphocytes (HP:0001922)2.95873928
33Cerebral edema (HP:0002181)2.95544114
34Exercise intolerance (HP:0003546)2.95031763
35Aplasia/Hypoplasia of the sacrum (HP:0008517)2.85302703
36Optic disc pallor (HP:0000543)2.84556831
37Lactic acidosis (HP:0003128)2.83696491
38Molar tooth sign on MRI (HP:0002419)2.65671022
39Abnormality of midbrain morphology (HP:0002418)2.65671022
40Glycosuria (HP:0003076)2.60928893
41Abnormality of urine glucose concentration (HP:0011016)2.60928893
42Patchy hypopigmentation of hair (HP:0011365)2.60264978
43Aplastic anemia (HP:0001915)2.58925572
44Hyperphosphaturia (HP:0003109)2.53787652
45Congenital ichthyosiform erythroderma (HP:0007431)2.51862710
46* Type I transferrin isoform profile (HP:0003642)2.51419002
47Hypothermia (HP:0002045)2.49440490
48Pancreatic fibrosis (HP:0100732)2.47461830
49Pancreatic cysts (HP:0001737)2.41481792
50Abnormality of secondary sexual hair (HP:0009888)2.41288889
51Abnormality of the axillary hair (HP:0100134)2.41288889
52Abnormality of dicarboxylic acid metabolism (HP:0010995)2.39195074
53Dicarboxylic aciduria (HP:0003215)2.39195074
54White forelock (HP:0002211)2.25309300
55Petechiae (HP:0000967)2.21074765
56Renal tubular dysfunction (HP:0000124)2.18264526
57Reduced antithrombin III activity (HP:0001976)2.17925768
58Congenital, generalized hypertrichosis (HP:0004540)2.17343742
59Nephronophthisis (HP:0000090)2.15313697
60Microvesicular hepatic steatosis (HP:0001414)2.14496905
61Hyperglycinemia (HP:0002154)2.13829540
62Abnormal pupillary function (HP:0007686)2.10991898
63Aplasia/hypoplasia of the uterus (HP:0008684)2.09991211
64Sclerocornea (HP:0000647)2.07674079
65Abnormal urine phosphate concentration (HP:0012599)2.06204971
66Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.02895318
67Abnormality of glycolysis (HP:0004366)2.02410642
68Increased serum pyruvate (HP:0003542)2.02410642
69Congenital primary aphakia (HP:0007707)1.99879349
70* Abnormal glycosylation (HP:0012345)1.94358846
71* Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.94358846
72* Abnormal protein N-linked glycosylation (HP:0012347)1.94358846
73* Abnormal protein glycosylation (HP:0012346)1.94358846
74Partial duplication of thumb phalanx (HP:0009944)1.92304544
75Gait imbalance (HP:0002141)1.92107503
76Ketosis (HP:0001946)1.90548678
77Amniotic constriction ring (HP:0009775)1.90309107
78Abnormality of placental membranes (HP:0011409)1.90309107
79Vomiting (HP:0002013)1.87111660
80Purpura (HP:0000979)1.87109296
81Testicular atrophy (HP:0000029)1.84745548
82CNS demyelination (HP:0007305)1.84599907
83Generalized aminoaciduria (HP:0002909)1.83966278
84Abnormal rod and cone electroretinograms (HP:0008323)1.83769593
85Medial flaring of the eyebrow (HP:0010747)1.83225532
86Abnormality of the anterior horn cell (HP:0006802)1.81458301
87Degeneration of anterior horn cells (HP:0002398)1.81458301
88Abnormality of the heme biosynthetic pathway (HP:0010472)1.80814811
89Progressive microcephaly (HP:0000253)1.79641731
90Absent rod-and cone-mediated responses on ERG (HP:0007688)1.78424392
91Ketoacidosis (HP:0001993)1.78313166
92Sensory axonal neuropathy (HP:0003390)1.78075966
93Hepatosplenomegaly (HP:0001433)1.76394820
94Poor head control (HP:0002421)1.74984575
95Congenital stationary night blindness (HP:0007642)1.74802707
96Cerebral hypomyelination (HP:0006808)1.73963261
97Male pseudohermaphroditism (HP:0000037)1.72363243
98Blindness (HP:0000618)1.71127894
99Elevated erythrocyte sedimentation rate (HP:0003565)1.70234858
100Abnormal respiratory motile cilium physiology (HP:0012261)1.67722093
101Abnormal hair whorl (HP:0010721)1.67058760
102IgM deficiency (HP:0002850)1.66435062
103Pancytopenia (HP:0001876)1.66097960
104Abnormal ciliary motility (HP:0012262)1.66055829
105Spastic paraparesis (HP:0002313)1.65714259
106Hypokinesia (HP:0002375)1.65250387
107Abnormality of magnesium homeostasis (HP:0004921)1.63657616
108Myokymia (HP:0002411)1.63366605
109Partial duplication of the phalanx of hand (HP:0009999)1.62234296
110Abnormality of the renal medulla (HP:0100957)1.62104487
111Thrombocytosis (HP:0001894)1.61902493
112Hypoplasia of the uterus (HP:0000013)1.61853437
113Retinal dysplasia (HP:0007973)1.61527505
114X-linked dominant inheritance (HP:0001423)1.61449430
115Decreased electroretinogram (ERG) amplitude (HP:0000654)1.61441098
116Hypoglycemic coma (HP:0001325)1.60818014
117Gliosis (HP:0002171)1.60335767
118Lethargy (HP:0001254)1.59731268
119Large for gestational age (HP:0001520)1.59457581
120Abnormal hemoglobin (HP:0011902)1.58560288
121True hermaphroditism (HP:0010459)1.58288687
122Methylmalonic aciduria (HP:0012120)1.57451400
123Abnormal respiratory motile cilium morphology (HP:0005938)1.57368546
124Abnormal respiratory epithelium morphology (HP:0012253)1.57368546
125Microretrognathia (HP:0000308)1.57202220
126Concave nail (HP:0001598)1.56886687
127Poor suck (HP:0002033)1.56343724
128Neutropenia (HP:0001875)1.54597668
129Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.54078288
130Metabolic acidosis (HP:0001942)1.53939027
131Emotional lability (HP:0000712)1.52930256
132Abnormality of aromatic amino acid family metabolism (HP:0004338)1.51909137
133Erythroderma (HP:0001019)1.51391357
134Methylmalonic acidemia (HP:0002912)1.50910416
135Nephrogenic diabetes insipidus (HP:0009806)1.50168731
136Hypomagnesemia (HP:0002917)1.48818492
137Nasolacrimal duct obstruction (HP:0000579)1.47829000
138Dry hair (HP:0011359)1.47535415
139Prolonged neonatal jaundice (HP:0006579)1.47489698

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.98253466
2NME24.05656433
3STK163.90157192
4MAP4K23.00552282
5VRK12.51441540
6PIM22.32933686
7STK392.31668031
8FRK2.27051375
9TLK12.21713316
10MST42.17661440
11TNIK2.14261526
12MAP3K122.07310376
13CASK2.06183782
14NME12.04490986
15IRAK42.01129167
16MAPKAPK51.94577230
17IRAK31.93620311
18PBK1.91846798
19OXSR11.85685294
20ADRBK21.85040093
21MAPK151.82858044
22GRK71.77758911
23MUSK1.75443303
24BMPR1B1.74593511
25BUB11.74388614
26ARAF1.73764591
27CDK191.68307394
28WNK31.66539724
29IRAK11.49915203
30INSRR1.46117234
31TAF11.43287865
32TEC1.37182860
33TXK1.33605316
34TESK11.32099794
35IRAK21.25455359
36MYLK1.24057079
37EIF2AK31.23625910
38BCKDK1.20080749
39PIK3CG1.13629919
40BTK1.10066212
41KIT1.09836383
42CSNK1G21.08202897
43PDK21.08111724
44SRPK11.07378307
45PHKG21.07242652
46PHKG11.07242652
47LRRK21.05354729
48BRAF1.01915308
49PINK11.01242803
50CSNK1G31.00976659
51WNK40.99339911
52BCR0.97437227
53YES10.96433950
54NUAK10.96035156
55MAP2K70.95493292
56BMPR20.94224928
57PKN10.94137220
58WEE10.93515942
59TNK20.93241696
60PRKCI0.93118153
61CDC70.92249173
62DAPK30.91855810
63DYRK20.91664808
64KDR0.90419044
65RPS6KA50.89921172
66NLK0.88537425
67DAPK10.87879116
68MAP4K10.87160947
69GRK10.86517171
70BLK0.86462132
71EPHB20.83941283
72MAP2K20.80931008
73PLK30.78994152
74DYRK30.78169429
75IKBKB0.77077559
76TRIM280.76257088
77PRPF4B0.76218514
78TESK20.75176602
79MAP2K60.75112748
80LIMK10.70977115
81MAPKAPK30.70156405
82PLK20.69505798
83LYN0.69447915
84ILK0.67642227
85CSNK1G10.66629782
86ABL20.65750403
87MAP3K140.65122245
88MKNK10.65064941
89SYK0.64202739
90NEK10.63353088
91TAOK30.61567544
92CLK10.61523798
93PRKCG0.61297956
94MAP3K110.61120790
95CDK80.60697907
96CAMK2B0.59276435
97UHMK10.58638251
98CCNB10.58036305
99FES0.56673675
100CAMK2D0.55541649
101AURKB0.55326821
102PASK0.54682640
103CSNK2A10.54380851
104LCK0.53481346
105PLK10.53134901
106GRK50.53094331
107RPS6KB20.52504049
108MST1R0.52419263
109IKBKE0.52041836
110EPHB10.51873316
111EIF2AK20.51641908
112PLK40.50725975
113PAK30.50230744
114ZAK0.50013851
115ADRBK10.48553224
116CSNK1A10.48337214
117CSNK1A1L0.48144497
118AURKA0.48123268
119BRSK20.48038166
120CHEK20.47865358
121CSNK2A20.47465557
122MET0.46193019
123ROCK20.45702365
124MAPK40.45417292
125MOS0.45401962
126FGFR20.44987329
127CAMK2G0.44739262
128PRKACA0.43724014
129MAPK130.43518019
130BRSK10.43293340
131MAP3K40.43164111
132EIF2AK10.42646339
133CDK30.41682532
134PRKCE0.41582273
135CSF1R0.41479445
136TIE10.41303845
137NEK60.41077826
138SIK30.40340942
139STK40.39090844
140ATR0.38563075
141PRKCA0.32120239
142PRKCQ0.30401809
143PRKACB0.27567582
144AKT20.26297968

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.85697059
2Oxidative phosphorylation_Homo sapiens_hsa001904.93392106
3Protein export_Homo sapiens_hsa030604.37806606
4Parkinsons disease_Homo sapiens_hsa050124.03584796
5Alzheimers disease_Homo sapiens_hsa050103.04344852
6Proteasome_Homo sapiens_hsa030503.02250631
7RNA polymerase_Homo sapiens_hsa030202.93719369
8Huntingtons disease_Homo sapiens_hsa050162.87640176
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.70592091
10Fatty acid elongation_Homo sapiens_hsa000622.24822535
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.00654498
12Sulfur metabolism_Homo sapiens_hsa009201.74931740
13Pyrimidine metabolism_Homo sapiens_hsa002401.69856816
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.69267989
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64650932
16Arachidonic acid metabolism_Homo sapiens_hsa005901.52190530
17Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.51652703
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.44739952
19SNARE interactions in vesicular transport_Homo sapiens_hsa041301.43386935
20Homologous recombination_Homo sapiens_hsa034401.42397528
21Ether lipid metabolism_Homo sapiens_hsa005651.38035998
22Steroid biosynthesis_Homo sapiens_hsa001001.25622725
23Folate biosynthesis_Homo sapiens_hsa007901.24634990
24Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.24272772
25Linoleic acid metabolism_Homo sapiens_hsa005911.23123854
26Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.21434780
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.18858268
28Other glycan degradation_Homo sapiens_hsa005111.18499841
29Cardiac muscle contraction_Homo sapiens_hsa042601.18077675
30Sphingolipid metabolism_Homo sapiens_hsa006001.14408034
31One carbon pool by folate_Homo sapiens_hsa006701.11434101
32DNA replication_Homo sapiens_hsa030301.08010041
33Spliceosome_Homo sapiens_hsa030401.07398037
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.03156571
35Basal transcription factors_Homo sapiens_hsa030221.00707525
36Purine metabolism_Homo sapiens_hsa002300.99727305
37Nucleotide excision repair_Homo sapiens_hsa034200.97513879
38Collecting duct acid secretion_Homo sapiens_hsa049660.96835447
39Glutathione metabolism_Homo sapiens_hsa004800.96262758
40Propanoate metabolism_Homo sapiens_hsa006400.95391326
41alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.93802251
42Mismatch repair_Homo sapiens_hsa034300.92252807
43Vibrio cholerae infection_Homo sapiens_hsa051100.90340044
44Rheumatoid arthritis_Homo sapiens_hsa053230.89798785
45* Metabolic pathways_Homo sapiens_hsa011000.88490498
46Tryptophan metabolism_Homo sapiens_hsa003800.85473285
47Primary bile acid biosynthesis_Homo sapiens_hsa001200.85106652
48Non-homologous end-joining_Homo sapiens_hsa034500.84158926
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.80848444
50Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.79925079
51Histidine metabolism_Homo sapiens_hsa003400.79155767
52Pyruvate metabolism_Homo sapiens_hsa006200.78024689
53Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.77938906
54Sulfur relay system_Homo sapiens_hsa041220.72761894
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.72118079
56Primary immunodeficiency_Homo sapiens_hsa053400.70568438
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68542429
58Nitrogen metabolism_Homo sapiens_hsa009100.67681887
59Autoimmune thyroid disease_Homo sapiens_hsa053200.63655900
60Graft-versus-host disease_Homo sapiens_hsa053320.62654869
61RNA degradation_Homo sapiens_hsa030180.62564875
62Peroxisome_Homo sapiens_hsa041460.62339890
63Allograft rejection_Homo sapiens_hsa053300.62272748
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.62269000
65Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60637113
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.60444136
67Asthma_Homo sapiens_hsa053100.59601115
68Phenylalanine metabolism_Homo sapiens_hsa003600.57689683
69Base excision repair_Homo sapiens_hsa034100.57565157
70Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57531851
71Fanconi anemia pathway_Homo sapiens_hsa034600.56465026
72Chemical carcinogenesis_Homo sapiens_hsa052040.56442343
73Fatty acid degradation_Homo sapiens_hsa000710.55926053
74Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.54682531
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54078451
76Selenocompound metabolism_Homo sapiens_hsa004500.54077779
77Hematopoietic cell lineage_Homo sapiens_hsa046400.53093010
78Regulation of autophagy_Homo sapiens_hsa041400.51843045
79Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.48819881
80Caffeine metabolism_Homo sapiens_hsa002320.48088936
81Vitamin B6 metabolism_Homo sapiens_hsa007500.47349496
82Phototransduction_Homo sapiens_hsa047440.47136090
83Intestinal immune network for IgA production_Homo sapiens_hsa046720.46103489
84Fatty acid metabolism_Homo sapiens_hsa012120.45208186
85Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45029462
86Carbon metabolism_Homo sapiens_hsa012000.43424142
87Lysosome_Homo sapiens_hsa041420.43356785
88* N-Glycan biosynthesis_Homo sapiens_hsa005100.41993358
89Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41198687
90Malaria_Homo sapiens_hsa051440.41053706
91Phagosome_Homo sapiens_hsa041450.40716804
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40411861
93Arginine and proline metabolism_Homo sapiens_hsa003300.40359496
94Tyrosine metabolism_Homo sapiens_hsa003500.39887608
95Retinol metabolism_Homo sapiens_hsa008300.39818603
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39040222
97Fructose and mannose metabolism_Homo sapiens_hsa000510.37405694
98Serotonergic synapse_Homo sapiens_hsa047260.37284112
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36694786
100Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36427630
101Systemic lupus erythematosus_Homo sapiens_hsa053220.35079332
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.33199896
103Mineral absorption_Homo sapiens_hsa049780.32903883
104Pertussis_Homo sapiens_hsa051330.32507226
105Drug metabolism - other enzymes_Homo sapiens_hsa009830.30724207
106RNA transport_Homo sapiens_hsa030130.30650578
107Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.27550080
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.26783563
109Fat digestion and absorption_Homo sapiens_hsa049750.26175060
110Vitamin digestion and absorption_Homo sapiens_hsa049770.22967023
111Pentose and glucuronate interconversions_Homo sapiens_hsa000400.22676159
112Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.21319790
113Butanoate metabolism_Homo sapiens_hsa006500.20898576
114Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.20283350
115Epstein-Barr virus infection_Homo sapiens_hsa051690.18776020
116Type I diabetes mellitus_Homo sapiens_hsa049400.18650307
117Glycosaminoglycan degradation_Homo sapiens_hsa005310.18214678
118NF-kappa B signaling pathway_Homo sapiens_hsa040640.16241462
119Alcoholism_Homo sapiens_hsa050340.16118233
120beta-Alanine metabolism_Homo sapiens_hsa004100.15079358
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.15064937
122NOD-like receptor signaling pathway_Homo sapiens_hsa046210.14524672
123Pentose phosphate pathway_Homo sapiens_hsa000300.14417630

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »