DPT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)7.43896782
2extracellular fibril organization (GO:0043206)5.98722044
3fibril organization (GO:0097435)5.14777994
4peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)5.03132016
5keratan sulfate catabolic process (GO:0042340)4.91575653
6* collagen fibril organization (GO:0030199)4.77603793
7cell migration involved in heart development (GO:0060973)4.72756088
8positive regulation of fatty acid oxidation (GO:0046321)4.49844746
9regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.42898640
10collagen metabolic process (GO:0032963)4.23205035
11multicellular organismal macromolecule metabolic process (GO:0044259)4.13538512
12low-density lipoprotein particle clearance (GO:0034383)4.13066657
13collagen catabolic process (GO:0030574)4.06390348
14multicellular organismal metabolic process (GO:0044236)4.01166033
15regulation of sequestering of triglyceride (GO:0010889)3.92105967
16retina vasculature morphogenesis in camera-type eye (GO:0061299)3.90044412
17multicellular organismal catabolic process (GO:0044243)3.84543855
18fatty acid transmembrane transport (GO:1902001)3.80784211
19extracellular matrix assembly (GO:0085029)3.75639238
20carnitine shuttle (GO:0006853)3.74433380
21blood vessel maturation (GO:0001955)3.73086147
22dermatan sulfate biosynthetic process (GO:0030208)3.72657999
23cellular response to vitamin (GO:0071295)3.70390927
24bone trabecula formation (GO:0060346)3.70316760
25glycerolipid catabolic process (GO:0046503)3.69585968
26barbed-end actin filament capping (GO:0051016)3.68157545
27transcytosis (GO:0045056)3.64794423
28positive regulation of fatty acid beta-oxidation (GO:0032000)3.62032562
29metanephric mesenchyme development (GO:0072075)3.59771198
30cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.56601676
31negative regulation of heart growth (GO:0061117)3.54895208
32negative regulation of cardiac muscle tissue growth (GO:0055022)3.54895208
33sequestering of extracellular ligand from receptor (GO:0035581)3.54253318
34regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.52444504
35negative regulation of smooth muscle cell migration (GO:0014912)3.50294327
36ovulation from ovarian follicle (GO:0001542)3.49996431
37regulation of fatty acid oxidation (GO:0046320)3.48162075
38glomerular filtration (GO:0003094)3.47037209
39negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)3.46304160
40ethanol oxidation (GO:0006069)3.44915468
41protein localization to cell surface (GO:0034394)3.43491762
42stress fiber assembly (GO:0043149)3.42420586
43dermatan sulfate metabolic process (GO:0030205)3.40731700
44extracellular matrix disassembly (GO:0022617)3.40689322
45venous blood vessel morphogenesis (GO:0048845)3.39379699
46brown fat cell differentiation (GO:0050873)3.38897258
47cGMP-mediated signaling (GO:0019934)3.37808266
48positive regulation of glycogen biosynthetic process (GO:0045725)3.37024942
49basement membrane organization (GO:0071711)3.34634766
50glomerular basement membrane development (GO:0032836)3.34330133
51endocrine hormone secretion (GO:0060986)3.33353467
52response to dietary excess (GO:0002021)3.33017880
53kidney mesenchyme development (GO:0072074)3.32201494
54lipid particle organization (GO:0034389)3.31358046
55NADH metabolic process (GO:0006734)3.30511806
56regulation of phospholipase A2 activity (GO:0032429)3.26299801
57polyol transport (GO:0015791)3.25063470
58negative regulation of granulocyte differentiation (GO:0030853)3.22259504
59adhesion of symbiont to host (GO:0044406)3.22236346
60apoptotic cell clearance (GO:0043277)3.18606087
61triglyceride catabolic process (GO:0019433)3.16525527
62renal filtration (GO:0097205)3.14772686
63plasma membrane repair (GO:0001778)3.14726767
64cellular response to epinephrine stimulus (GO:0071872)3.13573178
65skin morphogenesis (GO:0043589)3.10758829
66regulation of gonadotropin secretion (GO:0032276)3.09734281
67positive regulation of endothelial cell apoptotic process (GO:2000353)3.09727889
68positive regulation of macrophage cytokine production (GO:0060907)3.08831049
69lipid storage (GO:0019915)3.08302361
70regulation of integrin-mediated signaling pathway (GO:2001044)3.06964777
71endodermal cell differentiation (GO:0035987)3.05429849
72positive regulation of cholesterol efflux (GO:0010875)3.05105263
73regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.04630437
74regulation of skeletal muscle contraction (GO:0014819)3.03403819
75peptide cross-linking (GO:0018149)3.02508597
76cell proliferation involved in metanephros development (GO:0072203)3.00709984
77negative regulation of complement activation (GO:0045916)2.98377475
78positive regulation of macrophage derived foam cell differentiation (GO:0010744)2.97400680
79regulation of cholesterol storage (GO:0010885)2.95819905
80fatty acid homeostasis (GO:0055089)2.92319402
81white fat cell differentiation (GO:0050872)2.92086030
82positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.91755432
83regulation of plasminogen activation (GO:0010755)2.91093358
84regulation of macrophage derived foam cell differentiation (GO:0010743)2.90070699
85regulation of macrophage cytokine production (GO:0010935)2.89862708
86valine metabolic process (GO:0006573)2.89628669
87neuron projection extension involved in neuron projection guidance (GO:1902284)2.89368564
88axon extension involved in axon guidance (GO:0048846)2.89368564
89vascular endothelial growth factor signaling pathway (GO:0038084)2.86711031
90positive regulation of cellular response to insulin stimulus (GO:1900078)2.86657330
91trabecula formation (GO:0060343)2.84093240
92endothelial cell morphogenesis (GO:0001886)2.84014872
93negative regulation of protein autophosphorylation (GO:0031953)2.82156981
94positive regulation of glycogen metabolic process (GO:0070875)2.81902945
95negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.81613029
96regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.81468694
97carnitine transmembrane transport (GO:1902603)2.80672818
98muscle filament sliding (GO:0030049)2.80268198
99actin-myosin filament sliding (GO:0033275)2.80268198
100positive regulation of lipid storage (GO:0010884)2.80266155
101negative regulation of gluconeogenesis (GO:0045721)2.79912236
102biotin metabolic process (GO:0006768)2.79305601
103cardiac myofibril assembly (GO:0055003)2.79154379
104acylglycerol catabolic process (GO:0046464)2.78463020
105neutral lipid catabolic process (GO:0046461)2.78463020
106regulation of p38MAPK cascade (GO:1900744)2.76968589
107lymph vessel development (GO:0001945)2.76770174
108positive regulation of fatty acid metabolic process (GO:0045923)2.76642364
109regulation of glycogen (starch) synthase activity (GO:2000465)2.76447271
110hemidesmosome assembly (GO:0031581)2.75013834
111regulation of cAMP-dependent protein kinase activity (GO:2000479)2.72687650
112diacylglycerol metabolic process (GO:0046339)2.72127440
113ethanol metabolic process (GO:0006067)2.71695117
114positive regulation of glucose import (GO:0046326)2.69829416
115regulation of lipoprotein metabolic process (GO:0050746)2.68358069
116peripheral nervous system axon ensheathment (GO:0032292)2.68245955
117myelination in peripheral nervous system (GO:0022011)2.68245955
118negative regulation of smooth muscle cell proliferation (GO:0048662)2.67443338
119phagocytosis, recognition (GO:0006910)2.66839385
120positive regulation of metanephros development (GO:0072216)2.66329283
121positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.64441190
122* extracellular matrix organization (GO:0030198)2.64290634
123complement activation, alternative pathway (GO:0006957)2.63697330
124negative regulation of macrophage differentiation (GO:0045650)2.63627769
125regulation of fatty acid beta-oxidation (GO:0031998)2.63345356
126* extracellular structure organization (GO:0043062)2.63035217
127response to epinephrine (GO:0071871)2.62834458
128positive regulation of p38MAPK cascade (GO:1900745)2.62373051
129fatty acid beta-oxidation (GO:0006635)2.61868300
130positive regulation of glycolytic process (GO:0045821)2.61661287
131cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.61446602
132endothelium development (GO:0003158)2.60789027
133heart trabecula formation (GO:0060347)2.59117838
134positive regulation of sterol transport (GO:0032373)2.58176027
135positive regulation of cholesterol transport (GO:0032376)2.58176027
136growth hormone receptor signaling pathway (GO:0060396)2.57481120
137positive regulation of triglyceride lipase activity (GO:0061365)2.53208532
138positive regulation of lipoprotein lipase activity (GO:0051006)2.53208532
139carnitine transport (GO:0015879)2.52403685
140amino-acid betaine transport (GO:0015838)2.52403685
141actin-mediated cell contraction (GO:0070252)2.50245784
142adhesion of symbiont to host cell (GO:0044650)2.49754566
143virion attachment to host cell (GO:0019062)2.49754566
144positive regulation of osteoblast proliferation (GO:0033690)2.48677311
145fibroblast migration (GO:0010761)2.48397127
146myofibril assembly (GO:0030239)2.48253163
147negative regulation of cartilage development (GO:0061037)2.47073896
148protein trimerization (GO:0070206)2.45827820
149sulfur compound catabolic process (GO:0044273)2.45329361
150chondroitin sulfate catabolic process (GO:0030207)2.44386325
151positive regulation of glomerulus development (GO:0090193)2.43727479
152cardiac muscle cell proliferation (GO:0060038)2.40499612
153negative regulation of cardiac muscle hypertrophy (GO:0010614)2.39036286
154negative regulation of protein activation cascade (GO:2000258)2.37713420
155positive regulation of fat cell differentiation (GO:0045600)2.37235874

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse6.20714105
2TRIM28_21343339_ChIP-Seq_HEK293_Human5.35704885
3TP63_17297297_ChIP-ChIP_HaCaT_Human3.90216018
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.69145394
5CLOCK_20551151_ChIP-Seq_293T_Human3.55591084
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.07233868
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.03310875
8ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.73164002
9TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.67012623
10EP300_21415370_ChIP-Seq_HL-1_Mouse2.37434970
11CJUN_26792858_Chip-Seq_BT549_Human2.20613054
12ESR1_21235772_ChIP-Seq_MCF-7_Human2.18805250
13* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.13441942
14ESR2_21235772_ChIP-Seq_MCF-7_Human2.01037673
15CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.98526816
16CDX2_19796622_ChIP-Seq_MESCs_Mouse1.95757748
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.95022455
18BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.86596872
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.82312121
20PPAR_26484153_Chip-Seq_NCI-H1993_Human1.76771552
21RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.75458744
22FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.73644794
23ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.71353622
24GATA2_21666600_ChIP-Seq_HMVEC_Human1.68374727
25TBX20_22328084_ChIP-Seq_HEART_Mouse1.67811408
26TBX20_22080862_ChIP-Seq_HEART_Mouse1.67811408
27NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.65896901
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.59822493
29EZH2_22144423_ChIP-Seq_EOC_Human1.58793614
30LXR_22158963_ChIP-Seq_LIVER_Mouse1.58271988
31GATA1_22025678_ChIP-Seq_K562_Human1.53308567
32RXR_22158963_ChIP-Seq_LIVER_Mouse1.51408601
33EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.50207154
34AR_21572438_ChIP-Seq_LNCaP_Human1.45490227
35FOXO3_23340844_ChIP-Seq_DLD1_Human1.39915035
36SOX9_24532713_ChIP-Seq_HFSC_Mouse1.38468605
37JARID2_20075857_ChIP-Seq_MESCs_Mouse1.38203904
38SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.36996953
39SA1_22415368_ChIP-Seq_MEFs_Mouse1.36957650
40NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.36133620
41NRF2_20460467_ChIP-Seq_MEFs_Mouse1.36133620
42* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.35025274
43SMC3_22415368_ChIP-Seq_MEFs_Mouse1.31274217
44MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30649924
45SMAD_19615063_ChIP-ChIP_OVARY_Human1.28397565
46SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.27993950
47PPARA_22158963_ChIP-Seq_LIVER_Mouse1.27563480
48TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.27542412
49ELK3_25401928_ChIP-Seq_HUVEC_Human1.25686363
50EZH2_18974828_ChIP-Seq_MESCs_Mouse1.24854941
51RNF2_18974828_ChIP-Seq_MESCs_Mouse1.24854941
52BRD4_25478319_ChIP-Seq_HGPS_Human1.24656813
53WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24384972
54ZNF217_24962896_ChIP-Seq_MCF-7_Human1.22074852
55JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.21175442
56* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.20597123
57P63_26484246_Chip-Seq_KERATINOCYTES_Human1.19498676
58SOX2_20726797_ChIP-Seq_SW620_Human1.19336103
59EZH2_27304074_Chip-Seq_ESCs_Mouse1.18034264
60JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.17642017
61SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.13819238
62SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.13676178
63WT1_19549856_ChIP-ChIP_CCG9911_Human1.10866130
64PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.09352606
65TP53_18474530_ChIP-ChIP_U2OS_Human1.07882510
66EED_16625203_ChIP-ChIP_MESCs_Mouse1.07203937
67* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07064302
68RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.06035311
69RAD21_21589869_ChIP-Seq_MESCs_Mouse1.05360837
70PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.05126367
71KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04421191
72ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03374351
73SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.03126839
74SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.03126839
75THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.02474362
76KDM2B_26808549_Chip-Seq_SUP-B15_Human1.02328680
77BCAT_22108803_ChIP-Seq_LS180_Human1.02242400
78SMC1_22415368_ChIP-Seq_MEFs_Mouse1.02129542
79SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.01041120
80BP1_19119308_ChIP-ChIP_Hs578T_Human1.00949186
81GBX2_23144817_ChIP-Seq_PC3_Human0.99993249
82DROSHA_22980978_ChIP-Seq_HELA_Human0.99801330
83DNAJC2_21179169_ChIP-ChIP_NT2_Human0.99465899
84P300_27058665_Chip-Seq_ZR-75-30cells_Human0.98968053
85SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.98765498
86RNF2_27304074_Chip-Seq_ESCs_Mouse0.97296531
87ZNF263_19887448_ChIP-Seq_K562_Human0.96584219
88* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.96540728
89PIAS1_25552417_ChIP-Seq_VCAP_Human0.95072607
90MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.94533845
91SALL4_18804426_ChIP-ChIP_XEN_Mouse0.94342074
92STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.93090955
93FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.92375433
94* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91449964
95UBF1/2_26484160_Chip-Seq_HMECs_Human0.90540518
96PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.89901451
97RACK7_27058665_Chip-Seq_MCF-7_Human0.89842739
98TP53_23651856_ChIP-Seq_MEFs_Mouse0.89102798
99VDR_24787735_ChIP-Seq_THP-1_Human0.88270134
100WT1_25993318_ChIP-Seq_PODOCYTE_Human0.88191587
101MTF2_20144788_ChIP-Seq_MESCs_Mouse0.88062043
102ISL1_27105846_Chip-Seq_CPCs_Mouse0.87723323
103* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87290301
104TP53_16413492_ChIP-PET_HCT116_Human0.86693581
105AHR_22903824_ChIP-Seq_MCF-7_Human0.85326235
106LXR_22292898_ChIP-Seq_THP-1_Human0.84487942
107EZH2_27294783_Chip-Seq_ESCs_Mouse0.84388839
108SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.84381903
109KDM2B_26808549_Chip-Seq_K562_Human0.84255100
110UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.84011848
111NFIB_24661679_ChIP-Seq_LUNG_Mouse0.83732823
112Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.83363157
113SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.82732755
114* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.82425281
115TP53_20018659_ChIP-ChIP_R1E_Mouse0.81873221
116CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.81551167
117CSB_26484114_Chip-Seq_FIBROBLAST_Human0.80976885
118CTNNB1_20460455_ChIP-Seq_HCT116_Human0.80897933
119RUNX1_27514584_Chip-Seq_MCF-7_Human0.80748503
120TP63_23658742_ChIP-Seq_EP156T_Human0.80428403
121RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.79878179
122ERG_21242973_ChIP-ChIP_JURKAT_Human0.78537144
123JARID2_20064375_ChIP-Seq_MESCs_Mouse0.78219188
124ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.77217077
125PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.76589071
126SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75529976

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen8.95559610
2MP0005275_abnormal_skin_tensile7.14381379
3MP0005503_abnormal_tendon_morphology5.91766019
4MP0003705_abnormal_hypodermis_morpholog3.37367764
5MP0001958_emphysema3.11827317
6MP0000751_myopathy2.89840783
7MP0004272_abnormal_basement_membrane2.60452892
8MP0005670_abnormal_white_adipose2.49765041
9MP0002837_dystrophic_cardiac_calcinosis2.39448325
10MP0002108_abnormal_muscle_morphology2.30772396
11MP0003279_aneurysm2.20737115
12MP0010368_abnormal_lymphatic_system2.19320782
13* MP0002060_abnormal_skin_morphology2.16931189
14MP0004130_abnormal_muscle_cell2.11844988
15MP0005666_abnormal_adipose_tissue1.99499601
16MP0004185_abnormal_adipocyte_glucose1.79864711
17MP0006054_spinal_hemorrhage1.78740921
18MP0003566_abnormal_cell_adhesion1.74023728
19MP0000750_abnormal_muscle_regeneration1.71447971
20MP0005375_adipose_tissue_phenotype1.69545787
21MP0005508_abnormal_skeleton_morphology1.64815125
22MP0000013_abnormal_adipose_tissue1.56416070
23MP0002876_abnormal_thyroid_physiology1.47911199
24MP0000749_muscle_degeneration1.47129868
25MP0000003_abnormal_adipose_tissue1.43895927
26MP0005330_cardiomyopathy1.40490168
27MP0004084_abnormal_cardiac_muscle1.39726224
28MP0004087_abnormal_muscle_fiber1.33070058
29MP0002295_abnormal_pulmonary_circulatio1.32725687
30MP0001879_abnormal_lymphatic_vessel1.30644251
31MP0005369_muscle_phenotype1.26859821
32MP0003045_fibrosis1.24595136
33MP0000343_altered_response_to1.19074123
34MP0005620_abnormal_muscle_contractility1.18906994
35MP0005023_abnormal_wound_healing1.18228532
36MP0003646_muscle_fatigue1.16781346
37MP0004036_abnormal_muscle_relaxation1.16065142
38MP0003724_increased_susceptibility_to1.15351277
39MP0000759_abnormal_skeletal_muscle1.13868086
40MP0001661_extended_life_span1.12473773
41MP0005385_cardiovascular_system_phenoty1.11530592
42MP0001544_abnormal_cardiovascular_syste1.11530592
43MP0002106_abnormal_muscle_physiology1.10249875
44MP0002971_abnormal_brown_adipose1.07494129
45MP0004215_abnormal_myocardial_fiber1.06755223
46MP0006138_congestive_heart_failure1.05018240
47MP0003828_pulmonary_edema1.04576664
48MP0005257_abnormal_intraocular_pressure1.03917699
49MP0008775_abnormal_heart_ventricle1.03881578
50MP0003186_abnormal_redox_activity1.03537255
51MP0002972_abnormal_cardiac_muscle1.02063168
52MP0002933_joint_inflammation1.00339084
53* MP0001243_abnormal_dermal_layer1.00213174
54MP0002166_altered_tumor_susceptibility0.98091630
55MP0009384_cardiac_valve_regurgitation0.97365147
56MP0002796_impaired_skin_barrier0.96438311
57MP0000733_abnormal_muscle_development0.95405286
58MP0005390_skeleton_phenotype0.95309642
59MP0009115_abnormal_fat_cell0.91626330
60MP0000747_muscle_weakness0.88654342
61MP0003011_delayed_dark_adaptation0.88154001
62MP0001542_abnormal_bone_strength0.87888924
63MP0004484_altered_response_of0.86817468
64MP0010630_abnormal_cardiac_muscle0.85581980
65MP0005535_abnormal_body_temperature0.83248841
66MP0002168_other_aberrant_phenotype0.83233805
67MP0003950_abnormal_plasma_membrane0.82905631
68MP0005388_respiratory_system_phenotype0.82393519
69MP0002133_abnormal_respiratory_system0.82393519
70MP0005623_abnormal_meninges_morphology0.78715520
71MP0005595_abnormal_vascular_smooth0.77827487
72MP0000230_abnormal_systemic_arterial0.77341291
73MP0004858_abnormal_nervous_system0.76315866
74MP0003868_abnormal_feces_composition0.76172652
75MP0002998_abnormal_bone_remodeling0.75479438
76MP0003448_altered_tumor_morphology0.75461579
77MP0000767_abnormal_smooth_muscle0.75431364
78MP0005164_abnormal_response_to0.74764248
79MP0009250_abnormal_appendicular_skeleto0.74607830
80MP0004145_abnormal_muscle_electrophysio0.73691697
81MP0003690_abnormal_glial_cell0.73615839
82MP0005334_abnormal_fat_pad0.72967697
83MP0002896_abnormal_bone_mineralization0.72709475
84MP0002118_abnormal_lipid_homeostasis0.72210649
85MP0002006_tumorigenesis0.72159427
86MP0001533_abnormal_skeleton_physiology0.70278170
87MP0003252_abnormal_bile_duct0.68607339
88* MP0010771_integument_phenotype0.67624262
89MP0000163_abnormal_cartilage_morphology0.66995935
90MP0005167_abnormal_blood-brain_barrier0.66711382
91MP0005448_abnormal_energy_balance0.66137721
92MP0002269_muscular_atrophy0.65917912
93MP0002128_abnormal_blood_circulation0.65073006
94MP0010329_abnormal_lipoprotein_level0.64600695
95MP0003300_gastrointestinal_ulcer0.64557061
96MP0004883_abnormal_blood_vessel0.64291512
97MP0002254_reproductive_system_inflammat0.63413437
98MP0003115_abnormal_respiratory_system0.63303000
99MP0003191_abnormal_cellular_cholesterol0.62969223
100MP0001614_abnormal_blood_vessel0.62700894
101MP0002970_abnormal_white_adipose0.61030131
102MP0002638_abnormal_pupillary_reflex0.60644942
103MP0002115_abnormal_skeleton_extremities0.60311906
104MP0001299_abnormal_eye_distance/0.60024670
105MP0003283_abnormal_digestive_organ0.59602944
106MP0004134_abnormal_chest_morphology0.59570980
107MP0001175_abnormal_lung_morphology0.59565780
108MP0000249_abnormal_blood_vessel0.59196355
109MP0002113_abnormal_skeleton_development0.58015876
110* MP0005452_abnormal_adipose_tissue0.57508944
111MP0005171_absent_coat_pigmentation0.57336335
112MP0005165_increased_susceptibility_to0.56959172
113MP0009780_abnormal_chondrocyte_physiolo0.56763908
114MP0005647_abnormal_sex_gland0.56031685
115MP0003091_abnormal_cell_migration0.55872762
116MP0003385_abnormal_body_wall0.53811537
117MP0008004_abnormal_stomach_pH0.53320784
118MP0003959_abnormal_lean_body0.52706419

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.20995440
2Broad metatarsal (HP:0001783)6.09086461
3Premature rupture of membranes (HP:0001788)5.89354039
4Ankle contracture (HP:0006466)5.59119250
5Increased connective tissue (HP:0009025)5.38812647
6Type 1 muscle fiber predominance (HP:0003803)5.17725460
7Aortic dissection (HP:0002647)4.73176371
8Cerebral aneurysm (HP:0004944)4.35081960
9Follicular hyperkeratosis (HP:0007502)4.27928704
10Round ear (HP:0100830)4.10781539
11Soft skin (HP:0000977)4.05985476
12Muscle fiber splitting (HP:0003555)4.05487783
13Aortic aneurysm (HP:0004942)3.90813363
14Shallow orbits (HP:0000586)3.83166277
15Wrist flexion contracture (HP:0001239)3.81826842
16Spinal rigidity (HP:0003306)3.81194606
17Increased variability in muscle fiber diameter (HP:0003557)3.64496705
18Fragile skin (HP:0001030)3.55615735
19Atrophic scars (HP:0001075)3.51998373
20Slender build (HP:0001533)3.42058485
21Mitral valve prolapse (HP:0001634)3.40001022
22Dilatation of the ascending aorta (HP:0005111)3.36073790
23Cervical subluxation (HP:0003308)3.32561301
24Right ventricular cardiomyopathy (HP:0011663)3.29835403
25Abnormality of skeletal muscle fiber size (HP:0012084)3.29418115
26Bladder diverticulum (HP:0000015)3.24642359
27Striae distensae (HP:0001065)3.21246012
28Mildly elevated creatine phosphokinase (HP:0008180)3.10085647
29Abnormality of complement system (HP:0005339)3.03497789
30Aortic valve stenosis (HP:0001650)2.99364891
31Systemic lupus erythematosus (HP:0002725)2.84793262
32Vertebral compression fractures (HP:0002953)2.79118525
33Redundant skin (HP:0001582)2.77928875
34Hyporeflexia of lower limbs (HP:0002600)2.77420436
35Mitral stenosis (HP:0001718)2.74953961
36Lipoatrophy (HP:0100578)2.71273110
37Hypertriglyceridemia (HP:0002155)2.70415480
38Blue sclerae (HP:0000592)2.66664606
39Hyperextensible skin (HP:0000974)2.63238352
40Osteolytic defects of the phalanges of the hand (HP:0009771)2.62564178
41Osteolytic defects of the hand bones (HP:0009699)2.62564178
42Acanthosis nigricans (HP:0000956)2.61104834
43Difficulty running (HP:0009046)2.61043804
44Exercise-induced myalgia (HP:0003738)2.60250965
45Rectal prolapse (HP:0002035)2.56885969
46Alopecia of scalp (HP:0002293)2.54848970
47Aneurysm (HP:0002617)2.51321924
48Exercise-induced muscle cramps (HP:0003710)2.50683414
49Bowel diverticulosis (HP:0005222)2.44016315
50Back pain (HP:0003418)2.42274186
51Peritonitis (HP:0002586)2.39801723
52Pulmonary artery stenosis (HP:0004415)2.38444980
53Emphysema (HP:0002097)2.37644626
54Ovoid vertebral bodies (HP:0003300)2.36581523
55Limited hip movement (HP:0008800)2.35962286
56Sudden death (HP:0001699)2.35737410
57Ventricular tachycardia (HP:0004756)2.35713658
58Spondylolisthesis (HP:0003302)2.34739995
59Wormian bones (HP:0002645)2.34073267
60Myoglobinuria (HP:0002913)2.33776903
61Genu recurvatum (HP:0002816)2.30599808
62Joint laxity (HP:0001388)2.29156728
63Overgrowth (HP:0001548)2.28198749
64Venous abnormality (HP:0002624)2.22625228
65Thin bony cortex (HP:0002753)2.16971381
66Oligomenorrhea (HP:0000876)2.16373940
67Broad ribs (HP:0000885)2.15956988
68Neck muscle weakness (HP:0000467)2.15920107
69Vascular tortuosity (HP:0004948)2.13353267
70Generalized amyotrophy (HP:0003700)2.11675317
71Complement deficiency (HP:0004431)2.10505216
72Flat cornea (HP:0007720)2.09963667
73Mild short stature (HP:0003502)2.09502242
74Bone cyst (HP:0012062)2.09061215
75Spinal cord compression (HP:0002176)2.07854383
76Camptodactyly of toe (HP:0001836)2.07821061
77Venous insufficiency (HP:0005293)2.06521979
78Abnormality of the calf musculature (HP:0001430)2.06207316
79Delayed closure of the anterior fontanelle (HP:0001476)2.04270461
80Infantile muscular hypotonia (HP:0008947)2.02755479
81Calf muscle hypertrophy (HP:0008981)2.02070983
82Hematochezia (HP:0002573)1.96509550
83Polycythemia (HP:0001901)1.96364866
84Mitral regurgitation (HP:0001653)1.95704551
85Neoplasm of head and neck (HP:0012288)1.95313846
86Esophageal neoplasm (HP:0100751)1.95313846
87Abnormal delivery (HP:0001787)1.94731142
88Asymmetric septal hypertrophy (HP:0001670)1.92834707
89Reduced subcutaneous adipose tissue (HP:0003758)1.91201608
90Narrow nasal bridge (HP:0000446)1.89749722
91Tarsal synostosis (HP:0008368)1.89277688
92Aortic regurgitation (HP:0001659)1.88666643
93Biconcave vertebral bodies (HP:0004586)1.87328825
94Persistence of primary teeth (HP:0006335)1.87058650
95Ulnar deviation of the wrist (HP:0003049)1.86796277
96Gingival overgrowth (HP:0000212)1.86710632
97Bell-shaped thorax (HP:0001591)1.86240798
98Arterial tortuosity (HP:0005116)1.85787154
99Beaking of vertebral bodies (HP:0004568)1.85608665
100Wide anterior fontanel (HP:0000260)1.85603085
101Myocardial infarction (HP:0001658)1.84598447
102Myotonia (HP:0002486)1.84489223
103Muscle hypertrophy of the lower extremities (HP:0008968)1.84235246
104Elbow flexion contracture (HP:0002987)1.84134411
105Ectopia lentis (HP:0001083)1.84072160
106Neonatal short-limb short stature (HP:0008921)1.83907749
107Hip contracture (HP:0003273)1.83768232
108Lymphangioma (HP:0100764)1.83486956
109Abnormality of the acetabulum (HP:0003170)1.82045592
110Joint stiffness (HP:0001387)1.81672692
111Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.80836827
112Muscle fiber inclusion bodies (HP:0100299)1.80806326
113Disproportionate tall stature (HP:0001519)1.80194728
114Skin nodule (HP:0200036)1.79962593
115Osteoarthritis (HP:0002758)1.79201319
116EMG: myopathic abnormalities (HP:0003458)1.78104501
117Rhabdomyolysis (HP:0003201)1.76561913
118Delayed cranial suture closure (HP:0000270)1.76442991
119Hypoplasia of the iris (HP:0007676)1.75866877
120Small epiphyses (HP:0010585)1.75548417
121Insulin resistance (HP:0000855)1.75500346
122Limb-girdle muscle weakness (HP:0003325)1.74859531
123Hyperlipoproteinemia (HP:0010980)1.74128787
124Atrial fibrillation (HP:0005110)1.73293195
125Hypercortisolism (HP:0001578)1.71613206
126Facial diplegia (HP:0001349)1.70774187
127Hypoplasia of the odontoid process (HP:0003311)1.69647532
128Breech presentation (HP:0001623)1.67329279

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.31374821
2TTN3.95730172
3TGFBR22.99151231
4CAMK1D2.86168726
5ERN12.79764093
6SIK12.70070312
7PDGFRA2.64017728
8DDR22.49663966
9MYLK2.47528572
10RIPK12.41013668
11TESK12.19589856
12TIE12.16955729
13BCKDK2.10811629
14LMTK22.03840218
15CAMK1G2.03573201
16OBSCN1.98166732
17PDK31.93454490
18PDK41.93454490
19EPHB21.91663476
20MST1R1.91059970
21DMPK1.83924968
22PHKG11.83374909
23PHKG21.83374909
24LATS11.83169899
25FER1.59799568
26ABL21.59138793
27STK241.59107069
28STK38L1.58359534
29PDK21.56374234
30EPHA31.54553168
31FGFR41.50920940
32CAMK11.49137662
33PKN21.47631558
34EPHB11.47388975
35PIK3CA1.42534988
36LATS21.41899868
37MAPK71.22343720
38FGFR31.22160486
39JAK11.19438387
40TRPM71.15727784
41FGFR21.13638871
42MET1.11632536
43ILK1.09820350
44MAPK41.07281352
45NEK91.04991377
46PDGFRB1.04111785
47PRKCH1.02927652
48ADRBK11.02452419
49INSRR0.99465712
50PRKAA20.98549780
51FRK0.98449074
52PIK3CG0.98212037
53PTK60.98019051
54PAK20.94373524
55STK30.91426949
56PRKD10.89441178
57MAP3K30.85817938
58MARK20.84974186
59MAP3K70.82636613
60GRK50.78988599
61PRPF4B0.78358505
62BMX0.77853951
63MOS0.76748903
64PTK2B0.75140696
65PINK10.74887519
66PKN10.72735091
67LIMK10.72504328
68MAP2K10.71135520
69PRKD20.70303475
70ROCK10.69919438
71LRRK20.68524197
72STK380.68248707
73PRKG10.65710477
74RPS6KA20.65620016
75CSK0.65441758
76FGFR10.64478538
77GSK3A0.64199633
78MAPKAPK30.62408216
79MAP2K30.60363759
80MTOR0.59761510
81MAP3K60.57144326
82HIPK20.52964333
83MAP3K130.52385827
84TGFBR10.51862488
85PRKG20.51737839
86ARAF0.51641806
87CAMK2G0.50540585
88PAK40.50538820
89JAK30.50432313
90JAK20.50249027
91NLK0.49685004
92MAPK120.49246013
93PAK30.49236096
94PTK20.48310580
95SGK20.47978540
96CDK60.47743949
97EEF2K0.46128778
98TYK20.45967694
99ERBB30.45140664
100CAMKK20.44361948
101RET0.43753807
102SGK4940.43742177
103SGK2230.43742177
104SGK30.42333818
105DAPK30.41382825
106PRKAA10.40996759
107MAPK30.38360425
108ABL10.38256888
109FLT30.38103500
110PRKD30.37981133
111RPS6KL10.37187268
112RPS6KC10.37187268
113KDR0.37024378
114NTRK10.36811013
115ROCK20.36374525
116IGF1R0.33184694
117INSR0.32698971
118KIT0.32581640
119SRC0.31673984
120MAP2K20.30544294
121PRKCE0.29045304
122CDC42BPA0.28765845
123PRKACG0.28153943
124PIM20.27178646
125PDPK10.26115607
126CDK90.21748369
127ZAP700.21298487
128CAMK40.21073632
129MAPK110.20460871
130TBK10.19459772

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.59288087
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.88352367
3Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.62621594
4PPAR signaling pathway_Homo sapiens_hsa033202.61273455
5Propanoate metabolism_Homo sapiens_hsa006402.61107495
6Protein digestion and absorption_Homo sapiens_hsa049742.54203246
7Fatty acid biosynthesis_Homo sapiens_hsa000612.32518504
8Fatty acid metabolism_Homo sapiens_hsa012122.25342225
9Focal adhesion_Homo sapiens_hsa045102.25233631
10Fatty acid degradation_Homo sapiens_hsa000712.18621445
11Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.12644797
12Dilated cardiomyopathy_Homo sapiens_hsa054142.08525622
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.92442842
142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.84860091
15Amoebiasis_Homo sapiens_hsa051461.84123491
16Histidine metabolism_Homo sapiens_hsa003401.83314363
17Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.75063055
18Adipocytokine signaling pathway_Homo sapiens_hsa049201.74068068
19AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.72369205
20Malaria_Homo sapiens_hsa051441.66372289
21Insulin resistance_Homo sapiens_hsa049311.47177316
22Caffeine metabolism_Homo sapiens_hsa002321.39985959
23Proteoglycans in cancer_Homo sapiens_hsa052051.33276779
24Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.30537908
25AMPK signaling pathway_Homo sapiens_hsa041521.30158665
26Viral myocarditis_Homo sapiens_hsa054161.29278704
27Glycerolipid metabolism_Homo sapiens_hsa005611.22120817
28Starch and sucrose metabolism_Homo sapiens_hsa005001.15654516
29Small cell lung cancer_Homo sapiens_hsa052221.13007230
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.07617104
31TGF-beta signaling pathway_Homo sapiens_hsa043501.07203284
32Pyruvate metabolism_Homo sapiens_hsa006201.06057703
33Insulin signaling pathway_Homo sapiens_hsa049101.02518210
34Adherens junction_Homo sapiens_hsa045201.02266875
35Carbon metabolism_Homo sapiens_hsa012001.01819832
36PI3K-Akt signaling pathway_Homo sapiens_hsa041511.01240924
37Staphylococcus aureus infection_Homo sapiens_hsa051501.01054670
38Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00996500
39Complement and coagulation cascades_Homo sapiens_hsa046101.00980416
40Phospholipase D signaling pathway_Homo sapiens_hsa040721.00852496
41Toxoplasmosis_Homo sapiens_hsa051450.99240772
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.98921289
43Ovarian steroidogenesis_Homo sapiens_hsa049130.97975014
44Fat digestion and absorption_Homo sapiens_hsa049750.96977839
45beta-Alanine metabolism_Homo sapiens_hsa004100.93338144
46Circadian rhythm_Homo sapiens_hsa047100.83826844
47Longevity regulating pathway - mammal_Homo sapiens_hsa042110.81254863
48Renin secretion_Homo sapiens_hsa049240.75600152
49Nitrogen metabolism_Homo sapiens_hsa009100.75537405
50Central carbon metabolism in cancer_Homo sapiens_hsa052300.74964577
51Platelet activation_Homo sapiens_hsa046110.74935016
52Fatty acid elongation_Homo sapiens_hsa000620.73233816
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.73097249
54Glucagon signaling pathway_Homo sapiens_hsa049220.71067391
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70529798
56Other glycan degradation_Homo sapiens_hsa005110.69502140
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.69219883
58Bladder cancer_Homo sapiens_hsa052190.67599341
59Basal cell carcinoma_Homo sapiens_hsa052170.67144122
60Leukocyte transendothelial migration_Homo sapiens_hsa046700.66378614
61Glycosaminoglycan degradation_Homo sapiens_hsa005310.65273355
62Chronic myeloid leukemia_Homo sapiens_hsa052200.63791203
63Cyanoamino acid metabolism_Homo sapiens_hsa004600.63421978
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.61488276
65Pathways in cancer_Homo sapiens_hsa052000.61402704
66Retinol metabolism_Homo sapiens_hsa008300.61155459
67Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.60101403
68Galactose metabolism_Homo sapiens_hsa000520.59217853
69Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.59144336
70Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.58736551
71HIF-1 signaling pathway_Homo sapiens_hsa040660.56400813
72Gap junction_Homo sapiens_hsa045400.55966651
73Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55866318
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.55853660
75Prion diseases_Homo sapiens_hsa050200.55154393
76Acute myeloid leukemia_Homo sapiens_hsa052210.54596479
77TNF signaling pathway_Homo sapiens_hsa046680.54391228
78Melanoma_Homo sapiens_hsa052180.53644388
79Oxytocin signaling pathway_Homo sapiens_hsa049210.52677845
80Regulation of actin cytoskeleton_Homo sapiens_hsa048100.52619561
81Chemical carcinogenesis_Homo sapiens_hsa052040.52399283
82Type II diabetes mellitus_Homo sapiens_hsa049300.51691097
83Pancreatic cancer_Homo sapiens_hsa052120.51596885
84Phenylalanine metabolism_Homo sapiens_hsa003600.51561364
85Hippo signaling pathway_Homo sapiens_hsa043900.51485538
86Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51169645
87Tight junction_Homo sapiens_hsa045300.50270562
88Lysine degradation_Homo sapiens_hsa003100.49445201
89Arachidonic acid metabolism_Homo sapiens_hsa005900.49199587
90Tryptophan metabolism_Homo sapiens_hsa003800.48738686
91Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.47571919
92Glutathione metabolism_Homo sapiens_hsa004800.46811959
93Cardiac muscle contraction_Homo sapiens_hsa042600.46251089
94Lysosome_Homo sapiens_hsa041420.45975480
95Melanogenesis_Homo sapiens_hsa049160.45395668
96Renin-angiotensin system_Homo sapiens_hsa046140.45273687
97Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45136572
98Pertussis_Homo sapiens_hsa051330.45107372
99Osteoclast differentiation_Homo sapiens_hsa043800.44644857
100Peroxisome_Homo sapiens_hsa041460.43751914
101Ras signaling pathway_Homo sapiens_hsa040140.42186559
102Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42144008
103GnRH signaling pathway_Homo sapiens_hsa049120.41607996
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.41264792
105Butanoate metabolism_Homo sapiens_hsa006500.41237689
106Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.40476012
107Phagosome_Homo sapiens_hsa041450.39118232
108ABC transporters_Homo sapiens_hsa020100.37813663
109Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37654585
110Estrogen signaling pathway_Homo sapiens_hsa049150.35656267
111FoxO signaling pathway_Homo sapiens_hsa040680.35507552
112Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.35478945
113MicroRNAs in cancer_Homo sapiens_hsa052060.34836441
114Hedgehog signaling pathway_Homo sapiens_hsa043400.34739327
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.34621719
116cAMP signaling pathway_Homo sapiens_hsa040240.33550107
117Prostate cancer_Homo sapiens_hsa052150.33346513
118Rap1 signaling pathway_Homo sapiens_hsa040150.32944014
119Renal cell carcinoma_Homo sapiens_hsa052110.32537788
120Calcium signaling pathway_Homo sapiens_hsa040200.31856717
121Dorso-ventral axis formation_Homo sapiens_hsa043200.31356571
122Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.31039980
123Mineral absorption_Homo sapiens_hsa049780.30734739
124Tyrosine metabolism_Homo sapiens_hsa003500.30520622
125Thyroid hormone synthesis_Homo sapiens_hsa049180.30312726
126Notch signaling pathway_Homo sapiens_hsa043300.30097138
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.30074725
128Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.29752203
129Axon guidance_Homo sapiens_hsa043600.28611395
130Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28556433
131alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.27568218
132Arginine and proline metabolism_Homo sapiens_hsa003300.27308972

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