Rank | Gene Set | Z-score |
---|---|---|
1 | cilium or flagellum-dependent cell motility (GO:0001539) | 9.40751809 |
2 | axonemal dynein complex assembly (GO:0070286) | 6.62523625 |
3 | motile cilium assembly (GO:0044458) | 6.50049188 |
4 | cilium movement (GO:0003341) | 6.46277886 |
5 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.43090810 |
6 | epithelial cilium movement (GO:0003351) | 5.51252260 |
7 | axoneme assembly (GO:0035082) | 5.23667648 |
8 | tryptophan catabolic process (GO:0006569) | 4.08517032 |
9 | indole-containing compound catabolic process (GO:0042436) | 4.08517032 |
10 | indolalkylamine catabolic process (GO:0046218) | 4.08517032 |
11 | cilium organization (GO:0044782) | 4.00392685 |
12 | left/right axis specification (GO:0070986) | 3.96387873 |
13 | retinal cone cell development (GO:0046549) | 3.90343526 |
14 | cilium assembly (GO:0042384) | 3.87352592 |
15 | interkinetic nuclear migration (GO:0022027) | 3.80658645 |
16 | neural tube formation (GO:0001841) | 3.78243803 |
17 | indolalkylamine metabolic process (GO:0006586) | 3.75090187 |
18 | kynurenine metabolic process (GO:0070189) | 3.73579134 |
19 | regulation of cilium movement (GO:0003352) | 3.68180053 |
20 | ventricular system development (GO:0021591) | 3.66717582 |
21 | response to pheromone (GO:0019236) | 3.62316820 |
22 | tryptophan metabolic process (GO:0006568) | 3.62126983 |
23 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.60999161 |
24 | positive regulation of developmental pigmentation (GO:0048087) | 3.52724472 |
25 | photoreceptor cell maintenance (GO:0045494) | 3.49748543 |
26 | snRNA transcription (GO:0009301) | 3.49074467 |
27 | meiotic chromosome segregation (GO:0045132) | 3.47209048 |
28 | intraciliary transport (GO:0042073) | 3.37863492 |
29 | establishment of protein localization to Golgi (GO:0072600) | 3.32386075 |
30 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.27576849 |
31 | detection of light stimulus involved in visual perception (GO:0050908) | 3.27576849 |
32 | cellular component assembly involved in morphogenesis (GO:0010927) | 3.26747683 |
33 | protein localization to cilium (GO:0061512) | 3.25145933 |
34 | cilium morphogenesis (GO:0060271) | 3.24655795 |
35 | regulation of pigment cell differentiation (GO:0050932) | 3.17693519 |
36 | microtubule polymerization or depolymerization (GO:0031109) | 3.16977016 |
37 | rRNA catabolic process (GO:0016075) | 3.15923981 |
38 | regulation of hippo signaling (GO:0035330) | 3.14898902 |
39 | protein K48-linked deubiquitination (GO:0071108) | 3.13859718 |
40 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.13209296 |
41 | left/right pattern formation (GO:0060972) | 3.13102101 |
42 | behavioral response to nicotine (GO:0035095) | 3.10305837 |
43 | fucose catabolic process (GO:0019317) | 3.07777382 |
44 | L-fucose metabolic process (GO:0042354) | 3.07777382 |
45 | L-fucose catabolic process (GO:0042355) | 3.07777382 |
46 | regulation of establishment of cell polarity (GO:2000114) | 3.04623974 |
47 | regulation of sarcomere organization (GO:0060297) | 3.03732025 |
48 | retinal rod cell development (GO:0046548) | 3.02174556 |
49 | sperm motility (GO:0030317) | 3.00671189 |
50 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.00071248 |
51 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.00071248 |
52 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.00071248 |
53 | microtubule bundle formation (GO:0001578) | 2.96849521 |
54 | microtubule depolymerization (GO:0007019) | 2.88188536 |
55 | protein polyglutamylation (GO:0018095) | 2.87879171 |
56 | centriole replication (GO:0007099) | 2.87323800 |
57 | cellular biogenic amine catabolic process (GO:0042402) | 2.85550863 |
58 | amine catabolic process (GO:0009310) | 2.85550863 |
59 | indole-containing compound metabolic process (GO:0042430) | 2.81240596 |
60 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.78529336 |
61 | centriole assembly (GO:0098534) | 2.76475390 |
62 | protein K11-linked deubiquitination (GO:0035871) | 2.75998577 |
63 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.71187901 |
64 | reciprocal DNA recombination (GO:0035825) | 2.70694190 |
65 | reciprocal meiotic recombination (GO:0007131) | 2.70694190 |
66 | DNA methylation involved in gamete generation (GO:0043046) | 2.70212179 |
67 | regulation of gene silencing by RNA (GO:0060966) | 2.66385335 |
68 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.66385335 |
69 | regulation of gene silencing by miRNA (GO:0060964) | 2.66385335 |
70 | piRNA metabolic process (GO:0034587) | 2.63877785 |
71 | histone H3-K9 methylation (GO:0051567) | 2.63765013 |
72 | centrosome duplication (GO:0051298) | 2.63569042 |
73 | reflex (GO:0060004) | 2.63410324 |
74 | recombinational repair (GO:0000725) | 2.62258007 |
75 | double-strand break repair via homologous recombination (GO:0000724) | 2.60472720 |
76 | benzene-containing compound metabolic process (GO:0042537) | 2.60020891 |
77 | microtubule anchoring (GO:0034453) | 2.57211285 |
78 | NAD biosynthetic process (GO:0009435) | 2.53858059 |
79 | spinal cord motor neuron differentiation (GO:0021522) | 2.53151552 |
80 | microtubule-based movement (GO:0007018) | 2.52209758 |
81 | membrane depolarization during action potential (GO:0086010) | 2.51510622 |
82 | negative regulation of sodium ion transport (GO:0010766) | 2.50984127 |
83 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.49564757 |
84 | lipid translocation (GO:0034204) | 2.47531958 |
85 | phospholipid translocation (GO:0045332) | 2.47531958 |
86 | serotonin metabolic process (GO:0042428) | 2.45452748 |
87 | retina layer formation (GO:0010842) | 2.45121640 |
88 | microtubule severing (GO:0051013) | 2.44462945 |
89 | cellular ketone body metabolic process (GO:0046950) | 2.43277134 |
90 | cell projection assembly (GO:0030031) | 2.43070616 |
91 | oxidative demethylation (GO:0070989) | 2.40912093 |
92 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.39984570 |
93 | cellular response to sterol (GO:0036315) | 2.39493230 |
94 | protein K63-linked deubiquitination (GO:0070536) | 2.36857754 |
95 | cellular response to ethanol (GO:0071361) | 2.35391412 |
96 | protein targeting to Golgi (GO:0000042) | 2.35193743 |
97 | gamma-aminobutyric acid transport (GO:0015812) | 2.34826248 |
98 | behavioral response to ethanol (GO:0048149) | 2.34416517 |
99 | gene silencing by RNA (GO:0031047) | 2.33711327 |
100 | neuronal action potential (GO:0019228) | 2.33653541 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * GBX2_23144817_ChIP-Seq_PC3_Human | 3.31870046 |
2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.13635470 |
3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.12506942 |
4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.11812125 |
5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.10567772 |
6 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.07609278 |
7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.58440325 |
8 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.49860095 |
9 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.48477690 |
10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.39891033 |
11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.24317666 |
12 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 2.22681632 |
13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.21107382 |
14 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.21038795 |
15 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.11281505 |
16 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.07522537 |
17 | STAT3_23295773_ChIP-Seq_U87_Human | 2.07348551 |
18 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.05664178 |
19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04275213 |
20 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.02034376 |
21 | FUS_26573619_Chip-Seq_HEK293_Human | 2.01304463 |
22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.97400297 |
23 | * ER_23166858_ChIP-Seq_MCF-7_Human | 1.96859898 |
24 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.95652366 |
25 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.95065968 |
26 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.93138649 |
27 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.83389445 |
28 | TCF4_23295773_ChIP-Seq_U87_Human | 1.81659584 |
29 | P300_19829295_ChIP-Seq_ESCs_Human | 1.80440814 |
30 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.74570739 |
31 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.74570739 |
32 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.70587170 |
33 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.67998818 |
34 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.65262854 |
35 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.64611641 |
36 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.63638254 |
37 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.57055247 |
38 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54352379 |
39 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.54352379 |
40 | AR_25329375_ChIP-Seq_VCAP_Human | 1.52392675 |
41 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.51309881 |
42 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.48147512 |
43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.47803621 |
44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.46475468 |
45 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.44714654 |
46 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.42566362 |
47 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.41907178 |
48 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.41460033 |
49 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.41386761 |
50 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32104753 |
51 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 1.31997142 |
52 | TP53_16413492_ChIP-PET_HCT116_Human | 1.30992966 |
53 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.30422014 |
54 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.30156841 |
55 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.26958074 |
56 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.26462823 |
57 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.25713884 |
58 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.22906124 |
59 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.22852940 |
60 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21437106 |
61 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.19613209 |
62 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.18383737 |
63 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.16401968 |
64 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.16062956 |
65 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.13480698 |
66 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.10920136 |
67 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.09284653 |
68 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.07965972 |
69 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.07653072 |
70 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.06774089 |
71 | AR_19668381_ChIP-Seq_PC3_Human | 1.05866555 |
72 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.05630848 |
73 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.05279393 |
74 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.03833724 |
75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03552341 |
76 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02439332 |
77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02439332 |
78 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.02354480 |
79 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02171069 |
80 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02069665 |
81 | TBL1_22424771_ChIP-Seq_293T_Human | 1.01551040 |
82 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01192994 |
83 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.00607699 |
84 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.99497399 |
85 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.98644090 |
86 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.97774405 |
87 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.97582913 |
88 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96718522 |
89 | KDM2B_26808549_Chip-Seq_REH_Human | 0.96692569 |
90 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.96003411 |
91 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.95690452 |
92 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.95530261 |
93 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94777089 |
94 | RXR_22108803_ChIP-Seq_LS180_Human | 0.94179187 |
95 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.94120759 |
96 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.92868621 |
97 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92258783 |
98 | NFYB_21822215_ChIP-Seq_K562_Human | 0.91824883 |
99 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.91665822 |
100 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.91548849 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 3.77583977 |
2 | MP0000569_abnormal_digit_pigmentation | 3.19085145 |
3 | MP0009046_muscle_twitch | 2.84658918 |
4 | MP0002653_abnormal_ependyma_morphology | 2.75011496 |
5 | MP0003136_yellow_coat_color | 2.49064547 |
6 | MP0003646_muscle_fatigue | 2.30819363 |
7 | MP0003195_calcinosis | 2.30238014 |
8 | MP0004043_abnormal_pH_regulation | 2.27025174 |
9 | MP0005551_abnormal_eye_electrophysiolog | 2.24060743 |
10 | MP0001984_abnormal_olfaction | 2.23356812 |
11 | MP0001501_abnormal_sleep_pattern | 2.07106723 |
12 | MP0002735_abnormal_chemical_nociception | 2.06998294 |
13 | MP0008877_abnormal_DNA_methylation | 1.98257149 |
14 | MP0005253_abnormal_eye_physiology | 1.93715193 |
15 | MP0001968_abnormal_touch/_nociception | 1.91506967 |
16 | MP0006276_abnormal_autonomic_nervous | 1.91322445 |
17 | MP0005171_absent_coat_pigmentation | 1.90320058 |
18 | MP0000383_abnormal_hair_follicle | 1.83492038 |
19 | MP0003045_fibrosis | 1.80308854 |
20 | MP0001486_abnormal_startle_reflex | 1.76387720 |
21 | MP0009745_abnormal_behavioral_response | 1.73713850 |
22 | MP0005646_abnormal_pituitary_gland | 1.66643179 |
23 | MP0000427_abnormal_hair_cycle | 1.55486959 |
24 | MP0010094_abnormal_chromosome_stability | 1.52009885 |
25 | MP0003698_abnormal_male_reproductive | 1.49144350 |
26 | MP0002928_abnormal_bile_duct | 1.48799265 |
27 | MP0004147_increased_porphyrin_level | 1.47115293 |
28 | MP0002638_abnormal_pupillary_reflex | 1.45613505 |
29 | MP0002736_abnormal_nociception_after | 1.45360933 |
30 | MP0005410_abnormal_fertilization | 1.39345403 |
31 | MP0005174_abnormal_tail_pigmentation | 1.38663271 |
32 | MP0004142_abnormal_muscle_tone | 1.37827966 |
33 | MP0005645_abnormal_hypothalamus_physiol | 1.37706623 |
34 | MP0006072_abnormal_retinal_apoptosis | 1.36142783 |
35 | MP0002102_abnormal_ear_morphology | 1.34550093 |
36 | MP0000631_abnormal_neuroendocrine_gland | 1.33905058 |
37 | MP0002572_abnormal_emotion/affect_behav | 1.33368415 |
38 | MP0009697_abnormal_copulation | 1.32243485 |
39 | MP0008872_abnormal_physiological_respon | 1.31997197 |
40 | MP0002064_seizures | 1.31523241 |
41 | MP0003635_abnormal_synaptic_transmissio | 1.30528368 |
42 | MP0002168_other_aberrant_phenotype | 1.29533578 |
43 | MP0002272_abnormal_nervous_system | 1.28022437 |
44 | MP0001929_abnormal_gametogenesis | 1.27247100 |
45 | MP0010386_abnormal_urinary_bladder | 1.26757443 |
46 | MP0003787_abnormal_imprinting | 1.26197589 |
47 | MP0004133_heterotaxia | 1.25355530 |
48 | MP0001986_abnormal_taste_sensitivity | 1.24436114 |
49 | MP0002067_abnormal_sensory_capabilities | 1.23359088 |
50 | MP0001485_abnormal_pinna_reflex | 1.22926863 |
51 | MP0000372_irregular_coat_pigmentation | 1.22312439 |
52 | MP0008961_abnormal_basal_metabolism | 1.21523479 |
53 | MP0003890_abnormal_embryonic-extraembry | 1.19635274 |
54 | MP0002822_catalepsy | 1.17874481 |
55 | MP0008875_abnormal_xenobiotic_pharmacok | 1.17813739 |
56 | MP0002837_dystrophic_cardiac_calcinosis | 1.16689005 |
57 | MP0008995_early_reproductive_senescence | 1.13335414 |
58 | MP0002160_abnormal_reproductive_system | 1.13329233 |
59 | MP0002063_abnormal_learning/memory/cond | 1.11513319 |
60 | MP0004924_abnormal_behavior | 1.10313209 |
61 | MP0005386_behavior/neurological_phenoty | 1.10313209 |
62 | MP0003252_abnormal_bile_duct | 1.08519895 |
63 | MP0002095_abnormal_skin_pigmentation | 1.07938156 |
64 | MP0005266_abnormal_metabolism | 1.07900054 |
65 | MP0005310_abnormal_salivary_gland | 1.06874141 |
66 | MP0003878_abnormal_ear_physiology | 1.05736090 |
67 | MP0005377_hearing/vestibular/ear_phenot | 1.05736090 |
68 | MP0001970_abnormal_pain_threshold | 1.04922855 |
69 | MP0004130_abnormal_muscle_cell | 1.03670485 |
70 | MP0004145_abnormal_muscle_electrophysio | 1.02832449 |
71 | MP0002557_abnormal_social/conspecific_i | 1.01382089 |
72 | MP0002229_neurodegeneration | 0.98841721 |
73 | MP0000371_diluted_coat_color | 0.98191998 |
74 | MP0000015_abnormal_ear_pigmentation | 0.96990882 |
75 | MP0005220_abnormal_exocrine_pancreas | 0.95911707 |
76 | MP0004215_abnormal_myocardial_fiber | 0.95765417 |
77 | MP0004859_abnormal_synaptic_plasticity | 0.95613543 |
78 | MP0002396_abnormal_hematopoietic_system | 0.94305890 |
79 | MP0004381_abnormal_hair_follicle | 0.91542217 |
80 | MP0001502_abnormal_circadian_rhythm | 0.89232956 |
81 | MP0005075_abnormal_melanosome_morpholog | 0.88696315 |
82 | MP0002132_abnormal_respiratory_system | 0.88519772 |
83 | MP0005395_other_phenotype | 0.88050313 |
84 | MP0001664_abnormal_digestion | 0.87510062 |
85 | MP0003656_abnormal_erythrocyte_physiolo | 0.87141611 |
86 | MP0002009_preneoplasia | 0.86985184 |
87 | MP0008058_abnormal_DNA_repair | 0.86432768 |
88 | MP0002210_abnormal_sex_determination | 0.85263740 |
89 | MP0001963_abnormal_hearing_physiology | 0.85250054 |
90 | MP0002733_abnormal_thermal_nociception | 0.85025063 |
91 | MP0010678_abnormal_skin_adnexa | 0.84217125 |
92 | MP0004085_abnormal_heartbeat | 0.80907727 |
93 | MP0003137_abnormal_impulse_conducting | 0.79203659 |
94 | MP0002876_abnormal_thyroid_physiology | 0.78048387 |
95 | MP0005195_abnormal_posterior_eye | 0.76892167 |
96 | MP0002734_abnormal_mechanical_nocicepti | 0.76737895 |
97 | MP0003633_abnormal_nervous_system | 0.76653870 |
98 | MP0000653_abnormal_sex_gland | 0.75839864 |
99 | MP0005647_abnormal_sex_gland | 0.75733694 |
100 | MP0004742_abnormal_vestibular_system | 0.75165325 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.47231827 |
2 | Absent/shortened dynein arms (HP:0200106) | 6.47231827 |
3 | Abnormal ciliary motility (HP:0012262) | 5.97843180 |
4 | Abnormal respiratory epithelium morphology (HP:0012253) | 5.79702191 |
5 | Abnormal respiratory motile cilium morphology (HP:0005938) | 5.79702191 |
6 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 5.64556124 |
7 | Abnormal respiratory motile cilium physiology (HP:0012261) | 5.53473577 |
8 | Rhinitis (HP:0012384) | 4.62485927 |
9 | Genetic anticipation (HP:0003743) | 4.43172054 |
10 | Pancreatic cysts (HP:0001737) | 4.09559490 |
11 | Chronic hepatic failure (HP:0100626) | 4.09455162 |
12 | Pancreatic fibrosis (HP:0100732) | 3.98564469 |
13 | True hermaphroditism (HP:0010459) | 3.88248714 |
14 | Progressive cerebellar ataxia (HP:0002073) | 3.56199988 |
15 | Bronchiectasis (HP:0002110) | 3.52487446 |
16 | Hyperventilation (HP:0002883) | 3.51602420 |
17 | Nephronophthisis (HP:0000090) | 3.50573512 |
18 | Gaze-evoked nystagmus (HP:0000640) | 3.33390213 |
19 | Cystic liver disease (HP:0006706) | 3.30217398 |
20 | Abnormality of midbrain morphology (HP:0002418) | 3.29384551 |
21 | Molar tooth sign on MRI (HP:0002419) | 3.29384551 |
22 | Protruding tongue (HP:0010808) | 3.20466236 |
23 | Attenuation of retinal blood vessels (HP:0007843) | 3.19715466 |
24 | Medial flaring of the eyebrow (HP:0010747) | 3.12245841 |
25 | Abnormality of the renal medulla (HP:0100957) | 3.06832114 |
26 | Tubulointerstitial nephritis (HP:0001970) | 3.02648529 |
27 | Chronic bronchitis (HP:0004469) | 2.95142219 |
28 | Gait imbalance (HP:0002141) | 2.84332775 |
29 | Congenital primary aphakia (HP:0007707) | 2.82805316 |
30 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.70625989 |
31 | Absent speech (HP:0001344) | 2.65826554 |
32 | Febrile seizures (HP:0002373) | 2.58829416 |
33 | Abnormality of the renal cortex (HP:0011035) | 2.56909521 |
34 | Postaxial foot polydactyly (HP:0001830) | 2.56354170 |
35 | Clumsiness (HP:0002312) | 2.56151179 |
36 | Chronic sinusitis (HP:0011109) | 2.52210377 |
37 | Congenital hepatic fibrosis (HP:0002612) | 2.50868636 |
38 | Nephrogenic diabetes insipidus (HP:0009806) | 2.49195267 |
39 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.48221823 |
40 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.43845101 |
41 | Decreased circulating renin level (HP:0003351) | 2.41113039 |
42 | Central scotoma (HP:0000603) | 2.34057765 |
43 | Occipital encephalocele (HP:0002085) | 2.33447589 |
44 | Poor coordination (HP:0002370) | 2.29678948 |
45 | Nasal polyposis (HP:0100582) | 2.27617459 |
46 | Broad-based gait (HP:0002136) | 2.26887593 |
47 | Recurrent sinusitis (HP:0011108) | 2.24219080 |
48 | Congenital stationary night blindness (HP:0007642) | 2.23686078 |
49 | Tubular atrophy (HP:0000092) | 2.21019950 |
50 | Birth length less than 3rd percentile (HP:0003561) | 2.18874996 |
51 | Genital tract atresia (HP:0001827) | 2.18110064 |
52 | Cerebellar dysplasia (HP:0007033) | 2.17414079 |
53 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.16940762 |
54 | Anencephaly (HP:0002323) | 2.13779186 |
55 | Abnormal drinking behavior (HP:0030082) | 2.13548543 |
56 | Polydipsia (HP:0001959) | 2.13548543 |
57 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.12143932 |
58 | Vaginal atresia (HP:0000148) | 2.08754102 |
59 | Bronchitis (HP:0012387) | 2.06108154 |
60 | Focal seizures (HP:0007359) | 2.06004169 |
61 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.05851278 |
62 | Dysmetric saccades (HP:0000641) | 2.04442076 |
63 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.04258551 |
64 | Abolished electroretinogram (ERG) (HP:0000550) | 2.01541156 |
65 | Sclerocornea (HP:0000647) | 2.01180590 |
66 | Decreased central vision (HP:0007663) | 2.00045796 |
67 | Constricted visual fields (HP:0001133) | 1.97528758 |
68 | Retinitis pigmentosa (HP:0000510) | 1.96333898 |
69 | Chronic otitis media (HP:0000389) | 1.96170600 |
70 | Furrowed tongue (HP:0000221) | 1.92894225 |
71 | Type II lissencephaly (HP:0007260) | 1.92640340 |
72 | Dialeptic seizures (HP:0011146) | 1.91094641 |
73 | Male pseudohermaphroditism (HP:0000037) | 1.90980481 |
74 | Widely spaced teeth (HP:0000687) | 1.90348474 |
75 | Acute lymphatic leukemia (HP:0006721) | 1.86246715 |
76 | Fair hair (HP:0002286) | 1.86183306 |
77 | Infertility (HP:0000789) | 1.84119907 |
78 | Large for gestational age (HP:0001520) | 1.82297844 |
79 | Sloping forehead (HP:0000340) | 1.81029373 |
80 | Short foot (HP:0001773) | 1.76501920 |
81 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.76452868 |
82 | Patellar aplasia (HP:0006443) | 1.74820147 |
83 | Preaxial hand polydactyly (HP:0001177) | 1.73740390 |
84 | Abnormality of macular pigmentation (HP:0008002) | 1.72912770 |
85 | Postaxial hand polydactyly (HP:0001162) | 1.72094608 |
86 | Impaired smooth pursuit (HP:0007772) | 1.71568602 |
87 | Abnormal biliary tract physiology (HP:0012439) | 1.71507743 |
88 | Bile duct proliferation (HP:0001408) | 1.71507743 |
89 | Inability to walk (HP:0002540) | 1.70984114 |
90 | Congenital sensorineural hearing impairment (HP:0008527) | 1.70827766 |
91 | Tubulointerstitial abnormality (HP:0001969) | 1.70497902 |
92 | Oculomotor apraxia (HP:0000657) | 1.68360925 |
93 | Hyperkalemia (HP:0002153) | 1.68175867 |
94 | Highly arched eyebrow (HP:0002553) | 1.67103921 |
95 | Focal motor seizures (HP:0011153) | 1.66452300 |
96 | Astigmatism (HP:0000483) | 1.62671175 |
97 | Absence seizures (HP:0002121) | 1.61689232 |
98 | Small hand (HP:0200055) | 1.61652661 |
99 | Lissencephaly (HP:0001339) | 1.60502374 |
100 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.59762168 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 7.97066268 |
2 | ACVR1B | 3.50202497 |
3 | BMPR1B | 2.58527112 |
4 | MAPK15 | 2.53834597 |
5 | INSRR | 2.50860459 |
6 | TAOK3 | 2.50064425 |
7 | CDK12 | 2.47395665 |
8 | MAP3K4 | 2.37104623 |
9 | AKT3 | 2.35299945 |
10 | ZAK | 2.05284252 |
11 | TLK1 | 1.79729058 |
12 | MAPK13 | 1.78036178 |
13 | ADRBK2 | 1.72674034 |
14 | MAP4K2 | 1.69731725 |
15 | PINK1 | 1.59705168 |
16 | STK38L | 1.56527150 |
17 | MAP3K7 | 1.43450502 |
18 | MKNK2 | 1.33204037 |
19 | LATS1 | 1.31064773 |
20 | MAP2K7 | 1.30656078 |
21 | BRD4 | 1.22217242 |
22 | NTRK3 | 1.21040778 |
23 | GRK1 | 1.15073776 |
24 | OXSR1 | 1.13369922 |
25 | CAMKK2 | 1.10918614 |
26 | WNK3 | 1.04989182 |
27 | NUAK1 | 1.04933206 |
28 | NLK | 0.96677704 |
29 | CASK | 0.95676816 |
30 | MELK | 0.90970348 |
31 | SGK2 | 0.90380914 |
32 | EPHA3 | 0.89945276 |
33 | PLK4 | 0.89425062 |
34 | TEC | 0.89371286 |
35 | CSNK1A1L | 0.89040436 |
36 | SIK2 | 0.87619085 |
37 | PTK2B | 0.86461349 |
38 | DAPK2 | 0.85735976 |
39 | PRKAA2 | 0.85572651 |
40 | CAMK1G | 0.85355150 |
41 | BLK | 0.85204014 |
42 | RPS6KA5 | 0.82295611 |
43 | BRSK2 | 0.82068749 |
44 | FLT3 | 0.80013156 |
45 | OBSCN | 0.79302853 |
46 | ADRBK1 | 0.76069816 |
47 | PIK3CG | 0.75767944 |
48 | PRKAA1 | 0.75255473 |
49 | NEK2 | 0.74782864 |
50 | WNK1 | 0.72893265 |
51 | STK38 | 0.71866469 |
52 | MARK1 | 0.70109541 |
53 | TNK2 | 0.67800668 |
54 | TRPM7 | 0.66959774 |
55 | ATR | 0.64549565 |
56 | BTK | 0.64011452 |
57 | CDK19 | 0.63928864 |
58 | PKN1 | 0.63632645 |
59 | MAPK11 | 0.61533857 |
60 | BCR | 0.61516541 |
61 | EPHA4 | 0.60844160 |
62 | MKNK1 | 0.60517391 |
63 | MARK2 | 0.59711575 |
64 | CAMK4 | 0.58968976 |
65 | CHEK2 | 0.57484989 |
66 | KIT | 0.57290141 |
67 | CAMKK1 | 0.56330349 |
68 | CAMK1 | 0.56078236 |
69 | MAP2K4 | 0.55818667 |
70 | SGK494 | 0.53866876 |
71 | SGK223 | 0.53866876 |
72 | CAMK1D | 0.53591567 |
73 | IRAK1 | 0.53187732 |
74 | WNK4 | 0.52934390 |
75 | MARK3 | 0.52883910 |
76 | TGFBR1 | 0.52371893 |
77 | STK11 | 0.49847243 |
78 | CCNB1 | 0.49665549 |
79 | SYK | 0.49653112 |
80 | PNCK | 0.48231192 |
81 | STK39 | 0.47525503 |
82 | ATM | 0.46770168 |
83 | DYRK1A | 0.45372443 |
84 | ERBB2 | 0.44217939 |
85 | PRKCE | 0.43758860 |
86 | CAMK2A | 0.42993742 |
87 | PRKCQ | 0.41651503 |
88 | CSNK1G2 | 0.41021742 |
89 | SGK1 | 0.38674238 |
90 | TXK | 0.36957543 |
91 | CSNK1G1 | 0.36552777 |
92 | PLK1 | 0.35828138 |
93 | PAK3 | 0.35774466 |
94 | PDK1 | 0.35137929 |
95 | CDC7 | 0.34765128 |
96 | GSK3B | 0.34263773 |
97 | CSNK1D | 0.34081038 |
98 | CHUK | 0.33930819 |
99 | CSNK1G3 | 0.32169300 |
100 | HIPK2 | 0.31690811 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.76881169 |
2 | Homologous recombination_Homo sapiens_hsa03440 | 2.60790273 |
3 | ABC transporters_Homo sapiens_hsa02010 | 2.51064433 |
4 | Taste transduction_Homo sapiens_hsa04742 | 2.45446346 |
5 | Phototransduction_Homo sapiens_hsa04744 | 2.40800139 |
6 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.38352238 |
7 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.31331811 |
8 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.22735283 |
9 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.08056132 |
10 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.03223200 |
11 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.02700501 |
12 | Olfactory transduction_Homo sapiens_hsa04740 | 1.91394386 |
13 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.83684703 |
14 | Morphine addiction_Homo sapiens_hsa05032 | 1.73939014 |
15 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.69691477 |
16 | Circadian entrainment_Homo sapiens_hsa04713 | 1.62984046 |
17 | Circadian rhythm_Homo sapiens_hsa04710 | 1.58360428 |
18 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.56944309 |
19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.56770371 |
20 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.53539760 |
21 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.49893294 |
22 | Salivary secretion_Homo sapiens_hsa04970 | 1.49356545 |
23 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.48388657 |
24 | GABAergic synapse_Homo sapiens_hsa04727 | 1.45251625 |
25 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.42363614 |
26 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.41447449 |
27 | Lysine degradation_Homo sapiens_hsa00310 | 1.36791126 |
28 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.34989069 |
29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.20756408 |
30 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.19515678 |
31 | Alcoholism_Homo sapiens_hsa05034 | 1.15501206 |
32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.13460790 |
33 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.11988002 |
34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.10155047 |
35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.09980589 |
36 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.09587818 |
37 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.07801911 |
38 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.06249016 |
39 | Insulin secretion_Homo sapiens_hsa04911 | 1.06033661 |
40 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.05287965 |
41 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.00694886 |
42 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.98763536 |
43 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.98015095 |
44 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.97356480 |
45 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.92912353 |
46 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.92342914 |
47 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.91992753 |
48 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.90371114 |
49 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.88247135 |
50 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.87118004 |
51 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.85913345 |
52 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.84097367 |
53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.82401403 |
54 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.81830952 |
55 | Histidine metabolism_Homo sapiens_hsa00340 | 0.81322831 |
56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.78539690 |
57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.78447721 |
58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.76543463 |
59 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.75989004 |
60 | Renin secretion_Homo sapiens_hsa04924 | 0.75882205 |
61 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.73770408 |
62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.72902118 |
63 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.72273166 |
64 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.72219129 |
65 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71924696 |
66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.68307844 |
67 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.66552187 |
68 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.66050445 |
69 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65797844 |
70 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.65136780 |
71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.63977310 |
72 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63481167 |
73 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.62456154 |
74 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.62341074 |
75 | Purine metabolism_Homo sapiens_hsa00230 | 0.60859802 |
76 | Long-term depression_Homo sapiens_hsa04730 | 0.60617739 |
77 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.59837415 |
78 | Cocaine addiction_Homo sapiens_hsa05030 | 0.58963920 |
79 | Base excision repair_Homo sapiens_hsa03410 | 0.57823766 |
80 | Mismatch repair_Homo sapiens_hsa03430 | 0.57573800 |
81 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.56467198 |
82 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.54929227 |
83 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.51236098 |
84 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.50926753 |
85 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.46642428 |
86 | Peroxisome_Homo sapiens_hsa04146 | 0.45301210 |
87 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.43635311 |
88 | Platelet activation_Homo sapiens_hsa04611 | 0.41484175 |
89 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.41185896 |
90 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.40099078 |
91 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.39839527 |
92 | Cell cycle_Homo sapiens_hsa04110 | 0.36417028 |
93 | RNA polymerase_Homo sapiens_hsa03020 | 0.36157912 |
94 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.35843712 |
95 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.35434220 |
96 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.33718651 |
97 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.32409853 |
98 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.30772522 |
99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.30528234 |
100 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.28495411 |