Rank | Gene Set | Z-score |
---|---|---|
1 | * pyrimidine nucleobase catabolic process (GO:0006208) | 7.64401152 |
2 | layer formation in cerebral cortex (GO:0021819) | 6.84549418 |
3 | * nucleobase catabolic process (GO:0046113) | 6.03142635 |
4 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 5.97164231 |
5 | mitochondrion transport along microtubule (GO:0047497) | 5.97164231 |
6 | cell migration in hindbrain (GO:0021535) | 5.77961813 |
7 | neuron cell-cell adhesion (GO:0007158) | 5.67978929 |
8 | establishment of mitochondrion localization (GO:0051654) | 5.56400485 |
9 | central nervous system projection neuron axonogenesis (GO:0021952) | 5.42800716 |
10 | dendrite morphogenesis (GO:0048813) | 5.41072508 |
11 | axon extension (GO:0048675) | 5.10524865 |
12 | vocalization behavior (GO:0071625) | 5.05090302 |
13 | neuron recognition (GO:0008038) | 4.96560684 |
14 | dendritic spine morphogenesis (GO:0060997) | 4.96051637 |
15 | synaptic vesicle maturation (GO:0016188) | 4.94043315 |
16 | protein localization to synapse (GO:0035418) | 4.90815496 |
17 | postsynaptic membrane organization (GO:0001941) | 4.84259153 |
18 | locomotory exploration behavior (GO:0035641) | 4.83701062 |
19 | axonal fasciculation (GO:0007413) | 4.80891746 |
20 | negative regulation of microtubule polymerization (GO:0031115) | 4.78937209 |
21 | exploration behavior (GO:0035640) | 4.78104531 |
22 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.77196447 |
23 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.73387029 |
24 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.56057553 |
25 | neuron projection extension (GO:1990138) | 4.51607358 |
26 | positive regulation of axon extension (GO:0045773) | 4.45926429 |
27 | clathrin coat assembly (GO:0048268) | 4.40726429 |
28 | regulation of synapse structural plasticity (GO:0051823) | 4.39975460 |
29 | positive regulation of synapse maturation (GO:0090129) | 4.27802116 |
30 | central nervous system neuron axonogenesis (GO:0021955) | 4.25813867 |
31 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.15126358 |
32 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 4.14942798 |
33 | proline transport (GO:0015824) | 4.10212986 |
34 | regulation of axon extension (GO:0030516) | 3.93015298 |
35 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.91208540 |
36 | glutamate secretion (GO:0014047) | 3.90692941 |
37 | synaptic vesicle exocytosis (GO:0016079) | 3.89402718 |
38 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 3.85725337 |
39 | organelle transport along microtubule (GO:0072384) | 3.82689999 |
40 | regulation of microtubule polymerization (GO:0031113) | 3.78770013 |
41 | axon extension involved in axon guidance (GO:0048846) | 3.75818627 |
42 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.75818627 |
43 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.75679778 |
44 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 3.69244638 |
45 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.63627179 |
46 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.62368658 |
47 | cerebral cortex neuron differentiation (GO:0021895) | 3.48325707 |
48 | regulation of extent of cell growth (GO:0061387) | 3.47298315 |
49 | hippocampus development (GO:0021766) | 3.45985160 |
50 | axon cargo transport (GO:0008088) | 3.45609763 |
51 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.43869027 |
52 | cerebellum development (GO:0021549) | 3.43854660 |
53 | neuron migration (GO:0001764) | 3.43312664 |
54 | synapse assembly (GO:0007416) | 3.42352304 |
55 | dopamine receptor signaling pathway (GO:0007212) | 3.40385683 |
56 | regulation of axon extension involved in axon guidance (GO:0048841) | 3.39276842 |
57 | auditory behavior (GO:0031223) | 3.38464072 |
58 | developmental cell growth (GO:0048588) | 3.35205168 |
59 | paraxial mesoderm development (GO:0048339) | 3.32089206 |
60 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.29560399 |
61 | presynaptic membrane assembly (GO:0097105) | 3.28481126 |
62 | response to pheromone (GO:0019236) | 3.28417709 |
63 | positive regulation of microtubule polymerization (GO:0031116) | 3.25155334 |
64 | camera-type eye morphogenesis (GO:0048593) | 3.25053000 |
65 | regulation of synaptic vesicle transport (GO:1902803) | 3.23452039 |
66 | regulation of synapse maturation (GO:0090128) | 3.20976351 |
67 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.19294334 |
68 | activation of protein kinase A activity (GO:0034199) | 3.18950108 |
69 | neurotransmitter secretion (GO:0007269) | 3.16927184 |
70 | neuronal ion channel clustering (GO:0045161) | 3.14004700 |
71 | innervation (GO:0060384) | 3.11445500 |
72 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.10570915 |
73 | gamma-aminobutyric acid transport (GO:0015812) | 3.10536372 |
74 | establishment of nucleus localization (GO:0040023) | 3.09894447 |
75 | dendrite development (GO:0016358) | 3.06646735 |
76 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.05999434 |
77 | neuron projection morphogenesis (GO:0048812) | 3.05863408 |
78 | spinal cord development (GO:0021510) | 3.05829862 |
79 | generation of neurons (GO:0048699) | 3.05214623 |
80 | homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 3.02147722 |
81 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.01960212 |
82 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.01817301 |
83 | cerebellar granule cell differentiation (GO:0021707) | 3.01766264 |
84 | negative regulation of axon extension (GO:0030517) | 3.01722188 |
85 | axonogenesis (GO:0007409) | 3.00123824 |
86 | positive regulation of dendritic spine development (GO:0060999) | 3.00116168 |
87 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.99611331 |
88 | membrane assembly (GO:0071709) | 2.99575389 |
89 | cell communication by electrical coupling (GO:0010644) | 2.99353502 |
90 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.99142698 |
91 | synapse organization (GO:0050808) | 2.98581296 |
92 | apical protein localization (GO:0045176) | 2.98266903 |
93 | cerebellar Purkinje cell layer development (GO:0021680) | 2.98228511 |
94 | negative regulation of axonogenesis (GO:0050771) | 2.98220935 |
95 | positive regulation of synapse assembly (GO:0051965) | 2.95578223 |
96 | * positive regulation of filopodium assembly (GO:0051491) | 2.93698740 |
97 | presynaptic membrane organization (GO:0097090) | 2.93208590 |
98 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157) | 2.92648193 |
99 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.92471824 |
100 | cellular response to prostaglandin stimulus (GO:0071379) | 2.92236240 |
101 | retinal ganglion cell axon guidance (GO:0031290) | 2.90590683 |
102 | glutamate receptor signaling pathway (GO:0007215) | 2.89122447 |
103 | epithelial cell differentiation involved in kidney development (GO:0035850) | 2.87194788 |
104 | regulation of dendritic spine development (GO:0060998) | 2.86030569 |
105 | regulation of axonogenesis (GO:0050770) | 2.85957864 |
106 | positive regulation of axonogenesis (GO:0050772) | 2.85774121 |
107 | regulation of synapse organization (GO:0050807) | 2.85462440 |
108 | negative regulation of catenin import into nucleus (GO:0035414) | 2.85360293 |
109 | response to auditory stimulus (GO:0010996) | 2.84722552 |
110 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.84034923 |
111 | regulation of axon guidance (GO:1902667) | 2.82746887 |
112 | dendritic spine organization (GO:0097061) | 2.82483117 |
113 | convergent extension (GO:0060026) | 2.81960020 |
114 | cranial nerve morphogenesis (GO:0021602) | 2.81004612 |
115 | mechanosensory behavior (GO:0007638) | 2.79404745 |
116 | synaptic transmission, glutamatergic (GO:0035249) | 2.79131996 |
117 | ganglion development (GO:0061548) | 2.78045176 |
118 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.75993663 |
119 | regulation of synapse assembly (GO:0051963) | 2.75122121 |
120 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.72300399 |
121 | transmission of nerve impulse (GO:0019226) | 2.71256181 |
122 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.66354930 |
123 | lateral sprouting from an epithelium (GO:0060601) | 2.65604167 |
124 | mating behavior (GO:0007617) | 2.63153686 |
125 | cell-cell junction maintenance (GO:0045217) | 2.53850499 |
126 | negative chemotaxis (GO:0050919) | 2.53044682 |
127 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.52444332 |
128 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.50445063 |
129 | negative regulation of axon guidance (GO:1902668) | 2.50424728 |
130 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.50410829 |
131 | suckling behavior (GO:0001967) | 2.49980461 |
132 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.49093697 |
133 | regulation of neuron migration (GO:2001222) | 2.48525361 |
134 | semaphorin-plexin signaling pathway (GO:0071526) | 2.47824814 |
135 | regulation of gene silencing by RNA (GO:0060966) | 2.46426849 |
136 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.46426849 |
137 | regulation of gene silencing by miRNA (GO:0060964) | 2.46426849 |
138 | neurofilament cytoskeleton organization (GO:0060052) | 2.46022848 |
139 | behavioral response to nicotine (GO:0035095) | 2.44458659 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.41807942 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.13136924 |
3 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.97855508 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.91206241 |
5 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.80278041 |
6 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.79843628 |
7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.79500037 |
8 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.54536875 |
9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.54435615 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.50674225 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.50674225 |
12 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.47128780 |
13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.41935174 |
14 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.38237107 |
15 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.32627118 |
16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.32003626 |
17 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.31855046 |
18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.26248870 |
19 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.25565151 |
20 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.24732340 |
21 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.22122298 |
22 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.19829132 |
23 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.19336258 |
24 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.17436166 |
25 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.02770951 |
26 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.01886481 |
27 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.98922194 |
28 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.96032360 |
29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.90926476 |
30 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.90610048 |
31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.88503738 |
32 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.77038495 |
33 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.70241344 |
34 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.67878727 |
35 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.64465950 |
36 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.61890631 |
37 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.57960014 |
38 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.56234908 |
39 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54236520 |
40 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.53395655 |
41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.53198653 |
42 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.52992470 |
43 | * POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.46264917 |
44 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.44857475 |
45 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.43625905 |
46 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.42851824 |
47 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.41762698 |
48 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.40719944 |
49 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.39411203 |
50 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.38602531 |
51 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.34256817 |
52 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.33712734 |
53 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.33325678 |
54 | KDM2B_26808549_Chip-Seq_K562_Human | 1.33061635 |
55 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.31915055 |
56 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.31789659 |
57 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.30718391 |
58 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.28893361 |
59 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.28888942 |
60 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.27979524 |
61 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.26335562 |
62 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.25897640 |
63 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.23236760 |
64 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.22503502 |
65 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.21306276 |
66 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.20656522 |
67 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.20641210 |
68 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.20431241 |
69 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.20425123 |
70 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.20420536 |
71 | * NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.19760718 |
72 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.19628496 |
73 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.19438034 |
74 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.19222349 |
75 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.18785913 |
76 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.17851323 |
77 | AR_19668381_ChIP-Seq_PC3_Human | 1.17559871 |
78 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.17368212 |
79 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.17229838 |
80 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15969642 |
81 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.14535135 |
82 | AR_25329375_ChIP-Seq_VCAP_Human | 1.12860814 |
83 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.12446782 |
84 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.11994195 |
85 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.11558297 |
86 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.11456268 |
87 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.11433024 |
88 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.11396604 |
89 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09383440 |
90 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.09383440 |
91 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.09223310 |
92 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.08499356 |
93 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.07500875 |
94 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.06455214 |
95 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.06241345 |
96 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.05450486 |
97 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.04761036 |
98 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.04174362 |
99 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.03854404 |
100 | * EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.03226779 |
101 | STAT3_23295773_ChIP-Seq_U87_Human | 1.02132061 |
102 | * LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01925986 |
103 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.01310855 |
104 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.00944757 |
105 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00828406 |
106 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.00607589 |
107 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.00398700 |
108 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.00014793 |
109 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.99173790 |
110 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.98700393 |
111 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.98475199 |
112 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.98475199 |
113 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.98475199 |
114 | PRDM14_21183938_ChIP-Seq_MESCs_Mouse | 0.98310856 |
115 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.98050454 |
116 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.97369814 |
117 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.97018729 |
118 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.96775216 |
119 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.96015308 |
120 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.95783076 |
121 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.95136104 |
122 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.94902124 |
123 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.91407671 |
124 | * TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91221322 |
125 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91162199 |
126 | * JUN_21703547_ChIP-Seq_K562_Human | 0.90469848 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.12517465 |
2 | MP0004270_analgesia | 4.38160124 |
3 | MP0000778_abnormal_nervous_system | 3.72043517 |
4 | MP0005423_abnormal_somatic_nervous | 3.69228066 |
5 | MP0003635_abnormal_synaptic_transmissio | 3.30874235 |
6 | MP0002734_abnormal_mechanical_nocicepti | 2.99955928 |
7 | MP0002063_abnormal_learning/memory/cond | 2.94472875 |
8 | MP0003880_abnormal_central_pattern | 2.89673229 |
9 | MP0000569_abnormal_digit_pigmentation | 2.71262965 |
10 | MP0002735_abnormal_chemical_nociception | 2.64108119 |
11 | MP0009780_abnormal_chondrocyte_physiolo | 2.58672417 |
12 | MP0002184_abnormal_innervation | 2.53914325 |
13 | MP0004858_abnormal_nervous_system | 2.48195497 |
14 | MP0002822_catalepsy | 2.44908122 |
15 | MP0001968_abnormal_touch/_nociception | 2.38319186 |
16 | MP0002733_abnormal_thermal_nociception | 2.36992369 |
17 | MP0004811_abnormal_neuron_physiology | 2.18439623 |
18 | MP0009745_abnormal_behavioral_response | 2.16119315 |
19 | MP0002572_abnormal_emotion/affect_behav | 2.10306782 |
20 | MP0003329_amyloid_beta_deposits | 2.06797994 |
21 | MP0006276_abnormal_autonomic_nervous | 2.05856126 |
22 | MP0000955_abnormal_spinal_cord | 2.04355856 |
23 | MP0001348_abnormal_lacrimal_gland | 2.00882066 |
24 | MP0001440_abnormal_grooming_behavior | 1.91449666 |
25 | MP0003121_genomic_imprinting | 1.89281228 |
26 | MP0002557_abnormal_social/conspecific_i | 1.84964663 |
27 | MP0001970_abnormal_pain_threshold | 1.82280175 |
28 | MP0000537_abnormal_urethra_morphology | 1.80536972 |
29 | MP0002064_seizures | 1.75770399 |
30 | MP0001486_abnormal_startle_reflex | 1.73181289 |
31 | MP0004885_abnormal_endolymph | 1.72926311 |
32 | MP0005386_behavior/neurological_phenoty | 1.71374483 |
33 | MP0004924_abnormal_behavior | 1.71374483 |
34 | MP0002736_abnormal_nociception_after | 1.69237127 |
35 | MP0005187_abnormal_penis_morphology | 1.66223004 |
36 | MP0002882_abnormal_neuron_morphology | 1.65494365 |
37 | MP0003123_paternal_imprinting | 1.61386229 |
38 | MP0002152_abnormal_brain_morphology | 1.54825615 |
39 | MP0005257_abnormal_intraocular_pressure | 1.48451820 |
40 | MP0002067_abnormal_sensory_capabilities | 1.47793324 |
41 | MP0009046_muscle_twitch | 1.47413243 |
42 | MP0003861_abnormal_nervous_system | 1.46750585 |
43 | MP0000566_synostosis | 1.45674541 |
44 | MP0000049_abnormal_middle_ear | 1.45321127 |
45 | MP0008789_abnormal_olfactory_epithelium | 1.42287242 |
46 | MP0002909_abnormal_adrenal_gland | 1.41925447 |
47 | MP0004133_heterotaxia | 1.39179300 |
48 | MP0002102_abnormal_ear_morphology | 1.35501319 |
49 | MP0005499_abnormal_olfactory_system | 1.33364262 |
50 | MP0005394_taste/olfaction_phenotype | 1.33364262 |
51 | MP0002697_abnormal_eye_size | 1.32028653 |
52 | MP0001529_abnormal_vocalization | 1.30332040 |
53 | MP0000631_abnormal_neuroendocrine_gland | 1.27583077 |
54 | MP0010030_abnormal_orbit_morphology | 1.27390379 |
55 | MP0003937_abnormal_limbs/digits/tail_de | 1.27343030 |
56 | MP0003119_abnormal_digestive_system | 1.27272384 |
57 | MP0002066_abnormal_motor_capabilities/c | 1.25837941 |
58 | MP0005248_abnormal_Harderian_gland | 1.25723994 |
59 | MP0009379_abnormal_foot_pigmentation | 1.20991249 |
60 | MP0001984_abnormal_olfaction | 1.19546667 |
61 | MP0005645_abnormal_hypothalamus_physiol | 1.19251138 |
62 | MP0003787_abnormal_imprinting | 1.17062328 |
63 | MP0002751_abnormal_autonomic_nervous | 1.16051030 |
64 | MP0009250_abnormal_appendicular_skeleto | 1.12744297 |
65 | MP0006292_abnormal_olfactory_placode | 1.12377822 |
66 | MP0002272_abnormal_nervous_system | 1.11995411 |
67 | MP0005503_abnormal_tendon_morphology | 1.11985465 |
68 | MP0001188_hyperpigmentation | 1.09573669 |
69 | MP0003303_peritoneal_inflammation | 1.07673976 |
70 | MP0003136_yellow_coat_color | 1.06781161 |
71 | MP0002752_abnormal_somatic_nervous | 1.05397566 |
72 | MP0001299_abnormal_eye_distance/ | 1.03124597 |
73 | MP0002653_abnormal_ependyma_morphology | 1.02715797 |
74 | MP0001293_anophthalmia | 1.02456245 |
75 | MP0000751_myopathy | 1.00465577 |
76 | MP0003634_abnormal_glial_cell | 0.99964549 |
77 | MP0002234_abnormal_pharynx_morphology | 0.99569113 |
78 | MP0008569_lethality_at_weaning | 0.98226924 |
79 | MP0000462_abnormal_digestive_system | 0.97905015 |
80 | MP0000428_abnormal_craniofacial_morphol | 0.96308682 |
81 | MP0003137_abnormal_impulse_conducting | 0.93183061 |
82 | MP0005623_abnormal_meninges_morphology | 0.93014679 |
83 | MP0002638_abnormal_pupillary_reflex | 0.92798777 |
84 | MP0003385_abnormal_body_wall | 0.92484839 |
85 | MP0003567_abnormal_fetal_cardiomyocyte | 0.92465016 |
86 | MP0003942_abnormal_urinary_system | 0.91669555 |
87 | MP0002081_perinatal_lethality | 0.91642817 |
88 | MP0000534_abnormal_ureter_morphology | 0.91005099 |
89 | MP0001286_abnormal_eye_development | 0.90369910 |
90 | MP0003879_abnormal_hair_cell | 0.90038576 |
91 | MP0003221_abnormal_cardiomyocyte_apopto | 0.89658123 |
92 | MP0003935_abnormal_craniofacial_develop | 0.87789246 |
93 | MP0003122_maternal_imprinting | 0.87691820 |
94 | MP0004233_abnormal_muscle_weight | 0.87009083 |
95 | MP0000579_abnormal_nail_morphology | 0.86735112 |
96 | MP0004145_abnormal_muscle_electrophysio | 0.86388461 |
97 | MP0004085_abnormal_heartbeat | 0.85834439 |
98 | MP0004742_abnormal_vestibular_system | 0.84630744 |
99 | MP0002092_abnormal_eye_morphology | 0.84286190 |
100 | MP0009672_abnormal_birth_weight | 0.83917007 |
101 | MP0005409_darkened_coat_color | 0.83857428 |
102 | MP0000604_amyloidosis | 0.83319077 |
103 | MP0002249_abnormal_larynx_morphology | 0.82267318 |
104 | MP0004142_abnormal_muscle_tone | 0.81129097 |
105 | MP0009384_cardiac_valve_regurgitation | 0.80985392 |
106 | MP0004130_abnormal_muscle_cell | 0.80157230 |
107 | MP0002932_abnormal_joint_morphology | 0.79603403 |
108 | MP0002069_abnormal_eating/drinking_beha | 0.77001004 |
109 | MP0003938_abnormal_ear_development | 0.76791883 |
110 | MP0000516_abnormal_urinary_system | 0.73427221 |
111 | MP0005367_renal/urinary_system_phenotyp | 0.73427221 |
112 | MP0001905_abnormal_dopamine_level | 0.72572125 |
113 | MP0002896_abnormal_bone_mineralization | 0.72158388 |
114 | MP0003631_nervous_system_phenotype | 0.71887499 |
115 | MP0002233_abnormal_nose_morphology | 0.71119824 |
116 | MP0001502_abnormal_circadian_rhythm | 0.70063806 |
117 | MP0001177_atelectasis | 0.69321597 |
118 | MP0003632_abnormal_nervous_system | 0.69252910 |
119 | MP0009053_abnormal_anal_canal | 0.67250560 |
120 | MP0002116_abnormal_craniofacial_bone | 0.67027194 |
121 | MP0000015_abnormal_ear_pigmentation | 0.66991594 |
122 | MP0003633_abnormal_nervous_system | 0.66767789 |
123 | MP0003755_abnormal_palate_morphology | 0.66754962 |
124 | MP0010770_preweaning_lethality | 0.64875951 |
125 | MP0002082_postnatal_lethality | 0.64875951 |
126 | MP0003890_abnormal_embryonic-extraembry | 0.64195181 |
127 | MP0010769_abnormal_survival | 0.63210711 |
128 | MP0005195_abnormal_posterior_eye | 0.61520902 |
129 | MP0000026_abnormal_inner_ear | 0.60780738 |
130 | MP0006072_abnormal_retinal_apoptosis | 0.60716985 |
131 | MP0003283_abnormal_digestive_organ | 0.60635855 |
132 | MP0001943_abnormal_respiration | 0.60239171 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Amyotrophic lateral sclerosis (HP:0007354) | 5.19560080 |
2 | Mutism (HP:0002300) | 5.11682399 |
3 | Limb dystonia (HP:0002451) | 4.21342499 |
4 | Abnormality of the corticospinal tract (HP:0002492) | 4.07768460 |
5 | Supranuclear gaze palsy (HP:0000605) | 4.07472619 |
6 | Akinesia (HP:0002304) | 3.99492835 |
7 | Myokymia (HP:0002411) | 3.85743666 |
8 | Papilledema (HP:0001085) | 3.71239514 |
9 | Inappropriate behavior (HP:0000719) | 3.59490389 |
10 | Drooling (HP:0002307) | 3.50461809 |
11 | Excessive salivation (HP:0003781) | 3.50461809 |
12 | Cerebral inclusion bodies (HP:0100314) | 3.46420856 |
13 | Termporal pattern (HP:0011008) | 3.44185448 |
14 | Insidious onset (HP:0003587) | 3.44185448 |
15 | Ankle clonus (HP:0011448) | 3.43323291 |
16 | Visual hallucinations (HP:0002367) | 3.42864719 |
17 | Neurofibrillary tangles (HP:0002185) | 3.40149618 |
18 | Hepatoblastoma (HP:0002884) | 3.36694474 |
19 | Pachygyria (HP:0001302) | 3.34612423 |
20 | Cortical dysplasia (HP:0002539) | 3.27588003 |
21 | Disinhibition (HP:0000734) | 3.21940033 |
22 | Polyphagia (HP:0002591) | 3.16883863 |
23 | Apathy (HP:0000741) | 3.11337469 |
24 | Focal seizures (HP:0007359) | 3.03804978 |
25 | Lissencephaly (HP:0001339) | 2.98321086 |
26 | Hypoplasia of the brainstem (HP:0002365) | 2.97574307 |
27 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.97574307 |
28 | Obstructive sleep apnea (HP:0002870) | 2.96890558 |
29 | Epileptic encephalopathy (HP:0200134) | 2.96481680 |
30 | Broad-based gait (HP:0002136) | 2.94268135 |
31 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.87889408 |
32 | Diminished motivation (HP:0000745) | 2.83237145 |
33 | Turricephaly (HP:0000262) | 2.80296756 |
34 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.79498814 |
35 | Megalencephaly (HP:0001355) | 2.78859123 |
36 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.78270271 |
37 | Urinary urgency (HP:0000012) | 2.74042324 |
38 | Septo-optic dysplasia (HP:0100842) | 2.72683764 |
39 | Agitation (HP:0000713) | 2.69674495 |
40 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.66306559 |
41 | Poor eye contact (HP:0000817) | 2.63696468 |
42 | Cutaneous finger syndactyly (HP:0010554) | 2.63628285 |
43 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.63448659 |
44 | Aplasia of the phalanges of the hand (HP:0009802) | 2.63448659 |
45 | Aplasia involving bones of the extremities (HP:0009825) | 2.63448659 |
46 | Abnormality of binocular vision (HP:0011514) | 2.58421306 |
47 | Diplopia (HP:0000651) | 2.58421306 |
48 | Genetic anticipation (HP:0003743) | 2.57112720 |
49 | Progressive cerebellar ataxia (HP:0002073) | 2.56980165 |
50 | Cutaneous syndactyly (HP:0012725) | 2.56057394 |
51 | Broad metatarsal (HP:0001783) | 2.51567563 |
52 | Neoplasm of the adrenal cortex (HP:0100641) | 2.49724131 |
53 | Short 4th metacarpal (HP:0010044) | 2.46005334 |
54 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.46005334 |
55 | Torticollis (HP:0000473) | 2.45246516 |
56 | Subacute progressive viral hepatitis (HP:0006572) | 2.44826032 |
57 | Aqueductal stenosis (HP:0002410) | 2.44151535 |
58 | Sacral dimple (HP:0000960) | 2.40127555 |
59 | Abnormality of the lower motor neuron (HP:0002366) | 2.39595386 |
60 | Insomnia (HP:0100785) | 2.35659572 |
61 | Fetal akinesia sequence (HP:0001989) | 2.34360285 |
62 | Progressive inability to walk (HP:0002505) | 2.34312970 |
63 | Morphological abnormality of the middle ear (HP:0008609) | 2.33933228 |
64 | Amblyopia (HP:0000646) | 2.33870964 |
65 | Hypsarrhythmia (HP:0002521) | 2.33863551 |
66 | EEG with generalized epileptiform discharges (HP:0011198) | 2.31359926 |
67 | Hyperventilation (HP:0002883) | 2.27990765 |
68 | Vitreoretinal degeneration (HP:0000655) | 2.25448825 |
69 | Lower limb muscle weakness (HP:0007340) | 2.25319383 |
70 | Abnormal social behavior (HP:0012433) | 2.24627024 |
71 | Impaired social interactions (HP:0000735) | 2.24627024 |
72 | Vertebral arch anomaly (HP:0008438) | 2.24569653 |
73 | Partial agenesis of the corpus callosum (HP:0001338) | 2.22837511 |
74 | Spastic gait (HP:0002064) | 2.22308224 |
75 | Epileptiform EEG discharges (HP:0011182) | 2.21466844 |
76 | Abnormality of salivation (HP:0100755) | 2.21303123 |
77 | Hemiparesis (HP:0001269) | 2.20548921 |
78 | Lower limb amyotrophy (HP:0007210) | 2.18772391 |
79 | Hypoventilation (HP:0002791) | 2.18576752 |
80 | Abnormal eating behavior (HP:0100738) | 2.16914292 |
81 | Hyperacusis (HP:0010780) | 2.16464707 |
82 | Anomalous pulmonary venous return (HP:0010772) | 2.16428461 |
83 | Focal motor seizures (HP:0011153) | 2.13207266 |
84 | Inability to walk (HP:0002540) | 2.11837022 |
85 | Action tremor (HP:0002345) | 2.10685524 |
86 | Myelomeningocele (HP:0002475) | 2.10168699 |
87 | Stereotypic behavior (HP:0000733) | 2.09654012 |
88 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.08376667 |
89 | High anterior hairline (HP:0009890) | 2.07926858 |
90 | Abnormality of the astrocytes (HP:0100707) | 2.05030591 |
91 | Astrocytoma (HP:0009592) | 2.05030591 |
92 | Elfin facies (HP:0004428) | 2.04470080 |
93 | Sporadic (HP:0003745) | 2.03938072 |
94 | Shallow orbits (HP:0000586) | 2.03608476 |
95 | Abnormality of the 4th metacarpal (HP:0010012) | 2.03608366 |
96 | Gait imbalance (HP:0002141) | 2.03008789 |
97 | Spastic paraplegia (HP:0001258) | 2.02385608 |
98 | Papillary thyroid carcinoma (HP:0002895) | 2.02183059 |
99 | Focal dystonia (HP:0004373) | 2.01431976 |
100 | Trigonocephaly (HP:0000243) | 2.01124399 |
101 | Overgrowth (HP:0001548) | 2.00699705 |
102 | Paraplegia (HP:0010550) | 1.97719361 |
103 | Craniofacial dystonia (HP:0012179) | 1.97175781 |
104 | Pheochromocytoma (HP:0002666) | 1.96784968 |
105 | Sleep apnea (HP:0010535) | 1.96743178 |
106 | Bronchomalacia (HP:0002780) | 1.96510141 |
107 | Exotropia (HP:0000577) | 1.96208864 |
108 | Omphalocele (HP:0001539) | 1.96063893 |
109 | Heterotopia (HP:0002282) | 1.95792433 |
110 | Shoulder girdle muscle weakness (HP:0003547) | 1.94655288 |
111 | Hypoplasia of the corpus callosum (HP:0002079) | 1.94509568 |
112 | Choanal stenosis (HP:0000452) | 1.94442431 |
113 | Neonatal short-limb short stature (HP:0008921) | 1.93172143 |
114 | Shawl scrotum (HP:0000049) | 1.92990546 |
115 | Coronal craniosynostosis (HP:0004440) | 1.92159309 |
116 | Anophthalmia (HP:0000528) | 1.92132455 |
117 | Arnold-Chiari malformation (HP:0002308) | 1.91229097 |
118 | Polymicrogyria (HP:0002126) | 1.89258596 |
119 | Bowel diverticulosis (HP:0005222) | 1.89161774 |
120 | Depression (HP:0000716) | 1.88205398 |
121 | Large earlobe (HP:0009748) | 1.87445908 |
122 | Abnormality of the pulmonary veins (HP:0011718) | 1.85475275 |
123 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.85457373 |
124 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.85457373 |
125 | Renal duplication (HP:0000075) | 1.85262301 |
126 | Macroorchidism (HP:0000053) | 1.84994910 |
127 | Overriding aorta (HP:0002623) | 1.84829605 |
128 | Abnormality of the aortic arch (HP:0012303) | 1.84753925 |
129 | Bladder diverticulum (HP:0000015) | 1.83520777 |
130 | Split foot (HP:0001839) | 1.83205747 |
131 | Absent speech (HP:0001344) | 1.81376804 |
132 | Abnormality of the diencephalon (HP:0010662) | 1.80498050 |
133 | Generalized tonic-clonic seizures (HP:0002069) | 1.80485128 |
134 | Abnormality of the labia minora (HP:0012880) | 1.79494637 |
135 | Megalocornea (HP:0000485) | 1.79324153 |
136 | Open mouth (HP:0000194) | 1.79281677 |
137 | Broad long bones (HP:0005622) | 1.76134348 |
138 | Partial duplication of thumb phalanx (HP:0009944) | 1.76131037 |
139 | Wrist flexion contracture (HP:0001239) | 1.75579189 |
140 | Abnormality of dentin (HP:0010299) | 1.75215671 |
141 | Renovascular hypertension (HP:0100817) | 1.75114488 |
142 | Generalized hypotonia (HP:0001290) | 1.72666752 |
143 | Genu recurvatum (HP:0002816) | 1.70883432 |
144 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.69809123 |
145 | Flat cornea (HP:0007720) | 1.68957606 |
146 | Spina bifida occulta (HP:0003298) | 1.67673296 |
147 | Pointed chin (HP:0000307) | 1.67665056 |
148 | Failure to thrive in infancy (HP:0001531) | 1.67505448 |
149 | Narrow nasal bridge (HP:0000446) | 1.67495647 |
150 | Renal hypoplasia (HP:0000089) | 1.67464484 |
151 | Optic nerve hypoplasia (HP:0000609) | 1.66684090 |
152 | Precocious puberty (HP:0000826) | 1.66316399 |
153 | Broad finger (HP:0001500) | 1.65399225 |
154 | Broad thumb (HP:0011304) | 1.63689577 |
155 | Protruding tongue (HP:0010808) | 1.63134678 |
156 | Absent septum pellucidum (HP:0001331) | 1.62211805 |
157 | Broad phalanges of the hand (HP:0009768) | 1.60934285 |
158 | Wide anterior fontanel (HP:0000260) | 1.59436350 |
159 | Broad phalanx (HP:0006009) | 1.57913331 |
160 | Preaxial foot polydactyly (HP:0001841) | 1.54918821 |
161 | Abnormality of the septum pellucidum (HP:0007375) | 1.54845677 |
162 | Abnormality of the antihelix (HP:0009738) | 1.54824181 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 9.54910618 |
2 | MAP3K9 | 3.14475675 |
3 | PHKG2 | 2.86759542 |
4 | PHKG1 | 2.86759542 |
5 | MAPK13 | 2.67089815 |
6 | LATS2 | 2.60297031 |
7 | MINK1 | 2.55973516 |
8 | ERBB3 | 2.53753835 |
9 | NTRK2 | 2.27615726 |
10 | * DYRK2 | 2.21784305 |
11 | MAP3K4 | 2.17581666 |
12 | MAP2K7 | 1.87825128 |
13 | NTRK3 | 1.82820975 |
14 | SIK2 | 1.68741063 |
15 | PAK6 | 1.66335495 |
16 | CASK | 1.64912744 |
17 | KSR1 | 1.59007243 |
18 | CSNK1G2 | 1.55341867 |
19 | LIMK1 | 1.54515082 |
20 | EPHB2 | 1.54331306 |
21 | DAPK2 | 1.49195530 |
22 | MAP3K10 | 1.45300230 |
23 | NTRK1 | 1.20330697 |
24 | PKN1 | 1.19236011 |
25 | PLK2 | 1.18797284 |
26 | MARK2 | 1.15844635 |
27 | CSNK1G3 | 1.13968104 |
28 | EPHA3 | 1.11386144 |
29 | CAMK1D | 1.11236854 |
30 | CAMKK1 | 1.07868767 |
31 | * CDK5 | 1.06821007 |
32 | DMPK | 1.05935402 |
33 | MAP2K4 | 1.03108091 |
34 | CSNK1A1L | 1.03009735 |
35 | PAK3 | 0.99259935 |
36 | SCYL2 | 0.98908559 |
37 | RET | 0.98176444 |
38 | UHMK1 | 0.96521601 |
39 | MKNK1 | 0.95427982 |
40 | DYRK1A | 0.95328293 |
41 | RPS6KA2 | 0.94568308 |
42 | MKNK2 | 0.93807018 |
43 | CDK14 | 0.91974849 |
44 | EPHA4 | 0.91450060 |
45 | KSR2 | 0.89107924 |
46 | TAOK1 | 0.88715215 |
47 | PNCK | 0.88411174 |
48 | CDK18 | 0.87751682 |
49 | CDK15 | 0.87625052 |
50 | MAP3K6 | 0.87280159 |
51 | SGK2 | 0.87121250 |
52 | PRKCZ | 0.85628676 |
53 | MAPK12 | 0.85209857 |
54 | DYRK3 | 0.82791973 |
55 | CDK19 | 0.81660056 |
56 | CDK11A | 0.77158676 |
57 | PRKCG | 0.76423827 |
58 | PTK2 | 0.73389585 |
59 | DYRK1B | 0.73204968 |
60 | CSNK1G1 | 0.72860153 |
61 | TESK1 | 0.71118280 |
62 | TNIK | 0.70316852 |
63 | TYRO3 | 0.69901434 |
64 | LATS1 | 0.69786176 |
65 | MAP3K2 | 0.68731956 |
66 | STK11 | 0.68134333 |
67 | PRKD3 | 0.67915898 |
68 | PKN2 | 0.66306383 |
69 | ICK | 0.65855322 |
70 | ROCK2 | 0.64587740 |
71 | SGK3 | 0.63293669 |
72 | MAP2K6 | 0.62110152 |
73 | ILK | 0.59830117 |
74 | DAPK1 | 0.59407918 |
75 | PDGFRB | 0.58265896 |
76 | GRK5 | 0.57955670 |
77 | EIF2AK2 | 0.54459184 |
78 | PRKCI | 0.53703981 |
79 | ALK | 0.53515450 |
80 | CSNK1E | 0.53262107 |
81 | TAF1 | 0.52791295 |
82 | STK38L | 0.52086115 |
83 | CAMK2B | 0.50352541 |
84 | BRD4 | 0.50009338 |
85 | FYN | 0.49971029 |
86 | RIPK1 | 0.49671047 |
87 | MAPK9 | 0.49006191 |
88 | CAMK2A | 0.47565328 |
89 | FGFR2 | 0.45874637 |
90 | PAK2 | 0.45718186 |
91 | LMTK2 | 0.45502516 |
92 | TTN | 0.45022240 |
93 | TRIB3 | 0.44175073 |
94 | CAMK1G | 0.43628119 |
95 | FGFR1 | 0.43597577 |
96 | PRKCE | 0.42870785 |
97 | PRKDC | 0.41284409 |
98 | PRPF4B | 0.41262516 |
99 | CAMK4 | 0.40143007 |
100 | CSNK1D | 0.39735484 |
101 | MAPK10 | 0.39230710 |
102 | ROCK1 | 0.38424348 |
103 | WNK3 | 0.38338639 |
104 | CCNB1 | 0.38046020 |
105 | BCR | 0.37829434 |
106 | EEF2K | 0.36824203 |
107 | MAPK4 | 0.35139774 |
108 | * MTOR | 0.35033514 |
109 | PRKAA1 | 0.34658148 |
110 | * GSK3B | 0.34377932 |
111 | ABL2 | 0.33613422 |
112 | ERBB2 | 0.32740186 |
113 | MAP3K12 | 0.32537636 |
114 | TRIM28 | 0.32296567 |
115 | PDGFRA | 0.32077560 |
116 | STK24 | 0.31846465 |
117 | MAPK8 | 0.31686649 |
118 | DDR2 | 0.29716260 |
119 | PIK3CA | 0.27979637 |
120 | SGK1 | 0.27473822 |
121 | PRKCH | 0.24840271 |
122 | RPS6KB1 | 0.24734176 |
123 | RPS6KA3 | 0.24698438 |
124 | SGK223 | 0.24256558 |
125 | SGK494 | 0.24256558 |
126 | PRKG1 | 0.23432967 |
127 | CDC42BPA | 0.22870893 |
128 | GSK3A | 0.22363886 |
129 | PDK3 | 0.21628370 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Axon guidance_Homo sapiens_hsa04360 | 2.74624059 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.36058446 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.32604155 |
4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.20522363 |
5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.17749646 |
6 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.13599050 |
7 | Olfactory transduction_Homo sapiens_hsa04740 | 1.98969336 |
8 | GABAergic synapse_Homo sapiens_hsa04727 | 1.98384154 |
9 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.97129539 |
10 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.96177079 |
11 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.94563692 |
12 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.93622687 |
13 | Long-term potentiation_Homo sapiens_hsa04720 | 1.88552724 |
14 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.87326318 |
15 | Endometrial cancer_Homo sapiens_hsa05213 | 1.85571867 |
16 | Morphine addiction_Homo sapiens_hsa05032 | 1.81297087 |
17 | Gap junction_Homo sapiens_hsa04540 | 1.74748303 |
18 | Colorectal cancer_Homo sapiens_hsa05210 | 1.66481362 |
19 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.63232011 |
20 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.59806801 |
21 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.55614665 |
22 | Glioma_Homo sapiens_hsa05214 | 1.51618863 |
23 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.50959924 |
24 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.50849022 |
25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.48246364 |
26 | Adherens junction_Homo sapiens_hsa04520 | 1.47707023 |
27 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.45085668 |
28 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.44934472 |
29 | Long-term depression_Homo sapiens_hsa04730 | 1.43758210 |
30 | Cocaine addiction_Homo sapiens_hsa05030 | 1.42971970 |
31 | Renin secretion_Homo sapiens_hsa04924 | 1.42104633 |
32 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.39499936 |
33 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.35034531 |
34 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.33406437 |
35 | Viral myocarditis_Homo sapiens_hsa05416 | 1.28573830 |
36 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.28288869 |
37 | Salivary secretion_Homo sapiens_hsa04970 | 1.26623086 |
38 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.23670146 |
39 | Insulin secretion_Homo sapiens_hsa04911 | 1.23275246 |
40 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.22230318 |
41 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.21715105 |
42 | Melanogenesis_Homo sapiens_hsa04916 | 1.20197217 |
43 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.19792255 |
44 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.18890030 |
45 | Taste transduction_Homo sapiens_hsa04742 | 1.14026099 |
46 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.13048115 |
47 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.06428179 |
48 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.05684476 |
49 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.01748540 |
50 | Phototransduction_Homo sapiens_hsa04744 | 0.98223340 |
51 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.97172253 |
52 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.96193437 |
53 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.94803639 |
54 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.93400553 |
55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.91505834 |
56 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.90608155 |
57 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.90369350 |
58 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.90346548 |
59 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.88484287 |
60 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.86981193 |
61 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.86191590 |
62 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.85877263 |
63 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.85847792 |
64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.84370277 |
65 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.84286022 |
66 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.83698879 |
67 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.83433168 |
68 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.83257779 |
69 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.82669927 |
70 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.81499279 |
71 | Alcoholism_Homo sapiens_hsa05034 | 0.81011805 |
72 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.79079198 |
73 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.78452075 |
74 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.78242933 |
75 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.77132222 |
76 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.77122219 |
77 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.77011721 |
78 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.76609109 |
79 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.75578394 |
80 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.74494107 |
81 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.74242329 |
82 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.73997131 |
83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.72697553 |
84 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.72692967 |
85 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.72510218 |
86 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.72245606 |
87 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.71328862 |
88 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.69680040 |
89 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.69560541 |
90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.68917784 |
91 | Pathways in cancer_Homo sapiens_hsa05200 | 0.68746292 |
92 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.68426001 |
93 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.67106216 |
94 | Tight junction_Homo sapiens_hsa04530 | 0.66331927 |
95 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.65641618 |
96 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.65253913 |
97 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.63461863 |
98 | Endocytosis_Homo sapiens_hsa04144 | 0.63120285 |
99 | Prion diseases_Homo sapiens_hsa05020 | 0.60946433 |
100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.60667827 |
101 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.60567693 |
102 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.60455767 |
103 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.59169682 |
104 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.58236708 |
105 | Melanoma_Homo sapiens_hsa05218 | 0.57860195 |
106 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57420265 |
107 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57111922 |
108 | Focal adhesion_Homo sapiens_hsa04510 | 0.55853322 |
109 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.55442572 |
110 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.54811948 |
111 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.54761314 |
112 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.53769552 |
113 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.53589148 |
114 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.52585551 |
115 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.51599086 |
116 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.50335055 |
117 | Lysine degradation_Homo sapiens_hsa00310 | 0.49954027 |
118 | Bile secretion_Homo sapiens_hsa04976 | 0.49255777 |
119 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.45206036 |
120 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.44894404 |
121 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.43541413 |