DPYSL5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* pyrimidine nucleobase catabolic process (GO:0006208)8.17808166
2layer formation in cerebral cortex (GO:0021819)7.00261156
3* nucleobase catabolic process (GO:0046113)6.39072976
4central nervous system projection neuron axonogenesis (GO:0021952)5.74809324
5cell migration in hindbrain (GO:0021535)5.68120670
6neuron cell-cell adhesion (GO:0007158)5.63620289
7vocalization behavior (GO:0071625)5.42063768
8establishment of mitochondrion localization, microtubule-mediated (GO:0034643)5.33380071
9mitochondrion transport along microtubule (GO:0047497)5.33380071
10synaptic vesicle maturation (GO:0016188)5.32295803
11dendrite morphogenesis (GO:0048813)5.25710956
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.21034338
13dendritic spine morphogenesis (GO:0060997)5.11965063
14protein localization to synapse (GO:0035418)5.11664884
15establishment of mitochondrion localization (GO:0051654)5.05320848
16locomotory exploration behavior (GO:0035641)5.03838035
17neuron recognition (GO:0008038)5.03657262
18axonal fasciculation (GO:0007413)4.98908537
19regulation of short-term neuronal synaptic plasticity (GO:0048172)4.94926587
20regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.85194268
21exploration behavior (GO:0035640)4.78180932
22regulation of synapse structural plasticity (GO:0051823)4.72272483
23positive regulation of synapse maturation (GO:0090129)4.68796649
24negative regulation of microtubule polymerization (GO:0031115)4.64747005
25postsynaptic membrane organization (GO:0001941)4.51842382
26axon extension (GO:0048675)4.51570463
27clathrin coat assembly (GO:0048268)4.44064961
28response to pheromone (GO:0019236)4.41503767
29central nervous system neuron axonogenesis (GO:0021955)4.37357541
30synaptic vesicle exocytosis (GO:0016079)4.35074063
31positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.33288053
32regulation of glutamate receptor signaling pathway (GO:1900449)4.27258392
33glutamate secretion (GO:0014047)4.24267344
34cerebellar Purkinje cell layer development (GO:0021680)4.21443228
35regulation of synaptic vesicle exocytosis (GO:2000300)4.19779268
36neuron projection extension (GO:1990138)4.04338450
37positive regulation of axon extension (GO:0045773)4.02236524
38regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.99056236
39auditory behavior (GO:0031223)3.92308025
40proline transport (GO:0015824)3.88328210
41positive regulation of filopodium assembly (GO:0051491)3.83075040
42behavioral response to nicotine (GO:0035095)3.80533596
43regulation of axon extension (GO:0030516)3.76895367
44establishment of nucleus localization (GO:0040023)3.71946712
45retinal ganglion cell axon guidance (GO:0031290)3.67664459
46cerebral cortex neuron differentiation (GO:0021895)3.66521391
47cerebellum development (GO:0021549)3.63186879
48neurotransmitter-gated ion channel clustering (GO:0072578)3.62589852
49regulation of synaptic vesicle transport (GO:1902803)3.58167634
50organelle transport along microtubule (GO:0072384)3.57580807
51cerebral cortex radially oriented cell migration (GO:0021799)3.55815654
52synaptic vesicle docking involved in exocytosis (GO:0016081)3.54640706
53positive regulation of dendritic spine morphogenesis (GO:0061003)3.54435669
54neuron migration (GO:0001764)3.52867666
55axon cargo transport (GO:0008088)3.52096040
56regulation of synapse maturation (GO:0090128)3.51843256
57regulation of long-term neuronal synaptic plasticity (GO:0048169)3.51288274
58regulation of neuronal synaptic plasticity (GO:0048168)3.51015105
59hippocampus development (GO:0021766)3.48781189
60synapse assembly (GO:0007416)3.47184022
61regulation of microtubule polymerization (GO:0031113)3.46985447
62neurotransmitter secretion (GO:0007269)3.43760308
63gamma-aminobutyric acid transport (GO:0015812)3.42374318
64regulation of cAMP-dependent protein kinase activity (GO:2000479)3.40571434
65response to auditory stimulus (GO:0010996)3.38087841
66generation of neurons (GO:0048699)3.37904008
67spinal cord development (GO:0021510)3.37552485
68regulation of extent of cell growth (GO:0061387)3.37162969
69calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.33301216
70regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.33240906
71ionotropic glutamate receptor signaling pathway (GO:0035235)3.28948713
72positive regulation of dendritic spine development (GO:0060999)3.27063160
73dopamine receptor signaling pathway (GO:0007212)3.26072421
74positive regulation of microtubule polymerization or depolymerization (GO:0031112)3.24186654
75regulation of NFAT protein import into nucleus (GO:0051532)3.24002385
76neuronal ion channel clustering (GO:0045161)3.21077456
77regulation of dendritic spine morphogenesis (GO:0061001)3.20904420
78negative regulation of synaptic transmission, GABAergic (GO:0032229)3.14946795
79dendrite development (GO:0016358)3.14445255
80negative regulation of axon extension (GO:0030517)3.12393394
81activation of protein kinase A activity (GO:0034199)3.11132813
82negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.10080986
83neuromuscular synaptic transmission (GO:0007274)3.10054767
84neuron projection morphogenesis (GO:0048812)3.09639881
85cerebellar granule cell differentiation (GO:0021707)3.09596787
86nonmotile primary cilium assembly (GO:0035058)3.09419962
87negative regulation of catenin import into nucleus (GO:0035414)3.09229347
88negative regulation of axonogenesis (GO:0050771)3.08856189
89olfactory bulb development (GO:0021772)3.06457501
90neurofilament cytoskeleton organization (GO:0060052)3.06210934
91homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)3.06179818
92synaptic vesicle endocytosis (GO:0048488)3.04941758
93cell communication by electrical coupling (GO:0010644)3.04492589
94axonogenesis (GO:0007409)3.03815178
95regulation of synapse organization (GO:0050807)3.03291303
96positive regulation of synapse assembly (GO:0051965)3.02641739
97synapse organization (GO:0050808)3.02072193
98neuromuscular process controlling balance (GO:0050885)3.01599524
99transmission of nerve impulse (GO:0019226)3.01552227
100mechanosensory behavior (GO:0007638)3.01399418
101synaptic transmission, glutamatergic (GO:0035249)3.01024823
102forebrain neuron differentiation (GO:0021879)3.00132176
103adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.97812957
104glycosphingolipid biosynthetic process (GO:0006688)2.97339463
105dendritic spine organization (GO:0097061)2.96958505
106neuron-neuron synaptic transmission (GO:0007270)2.96938602
107glutamate receptor signaling pathway (GO:0007215)2.96539757
108intraspecies interaction between organisms (GO:0051703)2.96388195
109social behavior (GO:0035176)2.96388195
110developmental cell growth (GO:0048588)2.95951237
111regulation of respiratory system process (GO:0044065)2.95097111
112regulation of filopodium assembly (GO:0051489)2.91883972
113presynaptic membrane organization (GO:0097090)2.90936024
114regulation of axonogenesis (GO:0050770)2.89936637
115presynaptic membrane assembly (GO:0097105)2.89697434
116positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.88932038
117regulation of synapse assembly (GO:0051963)2.87652585
118positive regulation of synaptic transmission, GABAergic (GO:0032230)2.85636687
119regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.85239481
120startle response (GO:0001964)2.82256787
121limb bud formation (GO:0060174)2.80552431
122negative regulation of oligodendrocyte differentiation (GO:0048715)2.79905861
123adult walking behavior (GO:0007628)2.78336628
124neuronal action potential propagation (GO:0019227)2.76381484
125regulation of vesicle fusion (GO:0031338)2.72571085
126substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.65747077
127substrate-independent telencephalic tangential migration (GO:0021826)2.65747077
128G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.65591247
129axon extension involved in axon guidance (GO:0048846)2.64504171
130neuron projection extension involved in neuron projection guidance (GO:1902284)2.64504171
131membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.62228740
132positive regulation of mitochondrial fission (GO:0090141)2.62029663
133cranial nerve morphogenesis (GO:0021602)2.61138811
134spinal cord association neuron differentiation (GO:0021527)2.59571162
135regulation of axon guidance (GO:1902667)2.59355914
136cytoskeleton-dependent intracellular transport (GO:0030705)2.56966971

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.78503760
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.23485874
3CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.01206823
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.99055495
5GBX2_23144817_ChIP-Seq_PC3_Human2.88769068
6* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.83835265
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.83648885
8* REST_21632747_ChIP-Seq_MESCs_Mouse2.70034380
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.66580966
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.58536775
11EZH2_27294783_Chip-Seq_ESCs_Mouse2.53383695
12* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.51778731
13* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.51778731
14ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.49589970
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.46402046
16* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.37861821
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.37727069
18* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.36821972
19* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35480728
20* RNF2_27304074_Chip-Seq_ESCs_Mouse2.25261823
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25237490
22* REST_18959480_ChIP-ChIP_MESCs_Mouse2.24800832
23* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.23196936
24DROSHA_22980978_ChIP-Seq_HELA_Human2.21301728
25* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.18216241
26RBPJ_22232070_ChIP-Seq_NCS_Mouse2.14142884
27RARB_27405468_Chip-Seq_BRAIN_Mouse2.08805138
28EED_16625203_ChIP-ChIP_MESCs_Mouse2.05648003
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.02580992
30AR_21572438_ChIP-Seq_LNCaP_Human1.98423732
31MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.90944417
32* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.85249314
33ZNF274_21170338_ChIP-Seq_K562_Hela1.84096475
34IGF1R_20145208_ChIP-Seq_DFB_Human1.71827023
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.65246361
36* RING1B_27294783_Chip-Seq_ESCs_Mouse1.60317646
37RING1B_27294783_Chip-Seq_NPCs_Mouse1.58886672
38TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.55968954
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.55201597
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54229241
41* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.52377128
42TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.51238593
43PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.47048314
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47000179
45IKZF1_21737484_ChIP-ChIP_HCT116_Human1.45343871
46* KDM2B_26808549_Chip-Seq_K562_Human1.44072193
47FUS_26573619_Chip-Seq_HEK293_Human1.41114754
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.39456983
49RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.36722989
50* RNF2_27304074_Chip-Seq_NSC_Mouse1.36022954
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.35703451
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35465967
53ERG_21242973_ChIP-ChIP_JURKAT_Human1.35027937
54* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.34555663
55* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.33110793
56SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31171887
57DNAJC2_21179169_ChIP-ChIP_NT2_Human1.30866995
58GATA1_26923725_Chip-Seq_HPCs_Mouse1.26688011
59SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.26352535
60* SOX2_21211035_ChIP-Seq_LN229_Gbm1.23916268
61EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.23739348
62* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.22840857
63TAF15_26573619_Chip-Seq_HEK293_Human1.21805866
64BMI1_23680149_ChIP-Seq_NPCS_Mouse1.19568077
65* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.19298573
66SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.19216501
67RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.19098909
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.18868211
69SALL1_21062744_ChIP-ChIP_HESCs_Human1.17799163
70KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14950808
71* AR_19668381_ChIP-Seq_PC3_Human1.14593602
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.13521474
73EWS_26573619_Chip-Seq_HEK293_Human1.12002985
74* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.11587378
75FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.11246671
76P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10034150
77ZFP57_27257070_Chip-Seq_ESCs_Mouse1.10005950
78SMAD4_21799915_ChIP-Seq_A2780_Human1.09463574
79* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08364058
80TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07978608
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07978608
82NR3C1_23031785_ChIP-Seq_PC12_Mouse1.07844508
83MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.07627611
84IRF1_19129219_ChIP-ChIP_H3396_Human1.07048699
85SOX2_16153702_ChIP-ChIP_HESCs_Human1.06669684
86TOP2B_26459242_ChIP-Seq_MCF-7_Human1.05507255
87ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.05372486
88AR_25329375_ChIP-Seq_VCAP_Human1.04821638
89SMAD3_21741376_ChIP-Seq_EPCs_Human1.04525380
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.02097626
91CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.01787396
92TP53_20018659_ChIP-ChIP_R1E_Mouse1.00649785
93VDR_22108803_ChIP-Seq_LS180_Human1.00432339
94SMAD4_21741376_ChIP-Seq_HESCs_Human1.00409148
95STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.00335675
96CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.99579522
97MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.99492531
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99403058
99KDM2B_26808549_Chip-Seq_SUP-B15_Human0.99213175
100TET1_21490601_ChIP-Seq_MESCs_Mouse0.98839204
101PIAS1_25552417_ChIP-Seq_VCAP_Human0.98371032
102GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98287656
103* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97905316
104SMAD3_21741376_ChIP-Seq_ESCs_Human0.97393598
105CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.96954371
106BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.95990389
107AHR_22903824_ChIP-Seq_MCF-7_Human0.95706744
108SOX9_26525672_Chip-Seq_HEART_Mouse0.95618868
109* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.93827257
110P300_19829295_ChIP-Seq_ESCs_Human0.93246306
111* CTCF_27219007_Chip-Seq_Bcells_Human0.92602757
112* STAT3_23295773_ChIP-Seq_U87_Human0.91854867
113LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91286133
114ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90522942
115* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.89992586
116* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.89650092
117KDM2B_26808549_Chip-Seq_JURKAT_Human0.87855337
118TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.87734855
119UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87642001
120* RUNX2_22187159_ChIP-Seq_PCA_Human0.87248750
121CBP_20019798_ChIP-Seq_JUKART_Human0.87155562
122IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87155562
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.86514017
124TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86280954
125E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.85778949
126CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85648196
127* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.85618421
128JUN_21703547_ChIP-Seq_K562_Human0.85609681
129VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.84383328

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.62986764
2MP0004270_analgesia4.16929503
3MP0005423_abnormal_somatic_nervous3.88821582
4MP0000778_abnormal_nervous_system3.75187749
5MP0003635_abnormal_synaptic_transmissio3.51730154
6MP0003880_abnormal_central_pattern3.19170714
7MP0002063_abnormal_learning/memory/cond3.13934530
8MP0002734_abnormal_mechanical_nocicepti2.82226547
9MP0000569_abnormal_digit_pigmentation2.73757441
10MP0002822_catalepsy2.54580666
11MP0002184_abnormal_innervation2.49014915
12MP0009745_abnormal_behavioral_response2.41204863
13MP0002733_abnormal_thermal_nociception2.40305443
14MP0002735_abnormal_chemical_nociception2.38854443
15MP0006276_abnormal_autonomic_nervous2.38136514
16MP0009780_abnormal_chondrocyte_physiolo2.34368784
17MP0001968_abnormal_touch/_nociception2.28358450
18MP0002572_abnormal_emotion/affect_behav2.24946025
19MP0004811_abnormal_neuron_physiology2.24816593
20MP0001440_abnormal_grooming_behavior2.24678639
21MP0003329_amyloid_beta_deposits2.19096996
22MP0004858_abnormal_nervous_system2.17435288
23MP0000955_abnormal_spinal_cord2.07528608
24MP0002064_seizures2.05370278
25MP0002557_abnormal_social/conspecific_i2.01556778
26MP0001486_abnormal_startle_reflex1.94656564
27MP0001970_abnormal_pain_threshold1.87473567
28MP0001348_abnormal_lacrimal_gland1.74066185
29MP0004885_abnormal_endolymph1.73850797
30MP0002882_abnormal_neuron_morphology1.69977440
31MP0004924_abnormal_behavior1.68830257
32MP0005386_behavior/neurological_phenoty1.68830257
33MP0000537_abnormal_urethra_morphology1.65947100
34MP0009046_muscle_twitch1.65847218
35MP0002152_abnormal_brain_morphology1.60911907
36MP0005645_abnormal_hypothalamus_physiol1.58476043
37MP0005187_abnormal_penis_morphology1.54432222
38MP0002736_abnormal_nociception_after1.54281052
39MP0004142_abnormal_muscle_tone1.53553333
40MP0002067_abnormal_sensory_capabilities1.53375511
41MP0003861_abnormal_nervous_system1.52299331
42MP0000566_synostosis1.52153325
43MP0002909_abnormal_adrenal_gland1.51426494
44MP0000049_abnormal_middle_ear1.48343007
45MP0001984_abnormal_olfaction1.45423261
46MP0005499_abnormal_olfactory_system1.43949284
47MP0005394_taste/olfaction_phenotype1.43949284
48MP0002653_abnormal_ependyma_morphology1.40192063
49MP0000631_abnormal_neuroendocrine_gland1.38642532
50MP0008789_abnormal_olfactory_epithelium1.37964214
51MP0002066_abnormal_motor_capabilities/c1.34227476
52MP0002102_abnormal_ear_morphology1.33013368
53MP0003119_abnormal_digestive_system1.32612808
54MP0002272_abnormal_nervous_system1.27934923
55MP0003122_maternal_imprinting1.24986134
56MP0003879_abnormal_hair_cell1.23411201
57MP0001529_abnormal_vocalization1.18086197
58MP0008961_abnormal_basal_metabolism1.12192568
59MP0008569_lethality_at_weaning1.12172186
60MP0003787_abnormal_imprinting1.12051659
61MP0008877_abnormal_DNA_methylation1.10687028
62MP0003136_yellow_coat_color1.09658344
63MP0002752_abnormal_somatic_nervous1.04605559
64MP0005253_abnormal_eye_physiology1.03783466
65MP0001293_anophthalmia1.01627722
66MP0004742_abnormal_vestibular_system1.01163052
67MP0001501_abnormal_sleep_pattern1.00992724
68MP0002751_abnormal_autonomic_nervous1.00571555
69MP0006072_abnormal_retinal_apoptosis1.00557505
70MP0003137_abnormal_impulse_conducting0.99439934
71MP0002234_abnormal_pharynx_morphology0.99144695
72MP0002233_abnormal_nose_morphology0.97764930
73MP0005248_abnormal_Harderian_gland0.96366563
74MP0004233_abnormal_muscle_weight0.95758086
75MP0001299_abnormal_eye_distance/0.95479621
76MP0005551_abnormal_eye_electrophysiolog0.95027323
77MP0003634_abnormal_glial_cell0.94226477
78MP0000604_amyloidosis0.92655465
79MP0001502_abnormal_circadian_rhythm0.92453468
80MP0002249_abnormal_larynx_morphology0.91560034
81MP0002069_abnormal_eating/drinking_beha0.90628954
82MP0003937_abnormal_limbs/digits/tail_de0.90185608
83MP0003123_paternal_imprinting0.90062464
84MP0003283_abnormal_digestive_organ0.89732683
85MP0002938_white_spotting0.89176767
86MP0002081_perinatal_lethality0.85601699
87MP0005195_abnormal_posterior_eye0.85305380
88MP0001905_abnormal_dopamine_level0.84172950
89MP0003755_abnormal_palate_morphology0.82437047
90MP0004133_heterotaxia0.82321305
91MP0005391_vision/eye_phenotype0.81146336
92MP0002697_abnormal_eye_size0.80679788
93MP0003938_abnormal_ear_development0.79740362
94MP0002638_abnormal_pupillary_reflex0.79656675
95MP0001286_abnormal_eye_development0.79125609
96MP0001188_hyperpigmentation0.78606249
97MP0003890_abnormal_embryonic-extraembry0.78440468
98MP0003303_peritoneal_inflammation0.77625872
99MP0003631_nervous_system_phenotype0.75238905
100MP0001485_abnormal_pinna_reflex0.74775127
101MP0003633_abnormal_nervous_system0.73550648
102MP0004130_abnormal_muscle_cell0.72217801
103MP0001986_abnormal_taste_sensitivity0.71972179
104MP0003121_genomic_imprinting0.71095742
105MP0000534_abnormal_ureter_morphology0.70915321
106MP0000026_abnormal_inner_ear0.70443398
107MP0002082_postnatal_lethality0.69825801
108MP0010770_preweaning_lethality0.69825801
109MP0003632_abnormal_nervous_system0.68982764
110MP0010386_abnormal_urinary_bladder0.68697098
111MP0004085_abnormal_heartbeat0.68676150
112MP0010769_abnormal_survival0.68404946
113MP0002229_neurodegeneration0.67433435
114MP0002089_abnormal_postnatal_growth/wei0.66764188
115MP0001177_atelectasis0.64980774
116MP0003315_abnormal_perineum_morphology0.64258105
117MP0005646_abnormal_pituitary_gland0.64150922
118MP0010768_mortality/aging0.64082373
119MP0001963_abnormal_hearing_physiology0.63683273
120MP0003942_abnormal_urinary_system0.63454277
121MP0003385_abnormal_body_wall0.62868603
122MP0006292_abnormal_olfactory_placode0.61312144

Predicted human phenotypes

RankGene SetZ-score
1Mutism (HP:0002300)5.01575333
2Amyotrophic lateral sclerosis (HP:0007354)5.00238859
3Myokymia (HP:0002411)4.62545718
4Supranuclear gaze palsy (HP:0000605)4.28191709
5Visual hallucinations (HP:0002367)4.22354084
6Limb dystonia (HP:0002451)4.19447166
7Akinesia (HP:0002304)3.86654983
8Abnormality of the corticospinal tract (HP:0002492)3.83161549
9Ankle clonus (HP:0011448)3.70723147
10Focal seizures (HP:0007359)3.70533769
11Polyphagia (HP:0002591)3.61024041
12Cortical dysplasia (HP:0002539)3.60777287
13Drooling (HP:0002307)3.60495530
14Excessive salivation (HP:0003781)3.60495530
15Papilledema (HP:0001085)3.60214152
16Focal motor seizures (HP:0011153)3.55879641
17Neurofibrillary tangles (HP:0002185)3.34972649
18Cerebral inclusion bodies (HP:0100314)3.30090897
19Pachygyria (HP:0001302)3.24013249
20Epileptic encephalopathy (HP:0200134)3.23916727
21Inappropriate behavior (HP:0000719)3.20463465
22Lissencephaly (HP:0001339)3.10125647
23Aplasia/Hypoplasia of the brainstem (HP:0007362)3.06537900
24Hypoplasia of the brainstem (HP:0002365)3.06537900
25Broad-based gait (HP:0002136)3.04545018
26Insidious onset (HP:0003587)3.02756023
27Termporal pattern (HP:0011008)3.02756023
28Atrophy/Degeneration involving motor neurons (HP:0007373)3.00575989
29Apathy (HP:0000741)2.99907597
30Retinal dysplasia (HP:0007973)2.94028355
31Poor eye contact (HP:0000817)2.90332169
32Obstructive sleep apnea (HP:0002870)2.87374118
33Hepatoblastoma (HP:0002884)2.86170993
34Morphological abnormality of the pyramidal tract (HP:0002062)2.85896038
35Disinhibition (HP:0000734)2.77776827
36Diminished motivation (HP:0000745)2.72852545
37Urinary urgency (HP:0000012)2.72031737
38Abnormality of the lower motor neuron (HP:0002366)2.66998105
39Genetic anticipation (HP:0003743)2.66864138
40Abnormal eating behavior (HP:0100738)2.66168315
41Impaired social interactions (HP:0000735)2.64983725
42Abnormal social behavior (HP:0012433)2.64983725
43Megalencephaly (HP:0001355)2.63504056
44Torticollis (HP:0000473)2.62870800
45Aqueductal stenosis (HP:0002410)2.61159206
46Urinary bladder sphincter dysfunction (HP:0002839)2.60967383
47Hemiparesis (HP:0001269)2.60636373
48Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.60399717
49Progressive cerebellar ataxia (HP:0002073)2.59404535
50Abnormality of the labia minora (HP:0012880)2.56339567
51Insomnia (HP:0100785)2.56229969
52Diplopia (HP:0000651)2.50463770
53Abnormality of binocular vision (HP:0011514)2.50463770
54Agitation (HP:0000713)2.47797239
55Hypsarrhythmia (HP:0002521)2.47700985
56EEG with generalized epileptiform discharges (HP:0011198)2.46748012
57Spastic gait (HP:0002064)2.45354781
58Progressive inability to walk (HP:0002505)2.42585935
59Epileptiform EEG discharges (HP:0011182)2.38323473
60Sleep apnea (HP:0010535)2.37877471
61Abnormality of the astrocytes (HP:0100707)2.36978249
62Astrocytoma (HP:0009592)2.36978249
63Hyperacusis (HP:0010780)2.36380920
64Medial flaring of the eyebrow (HP:0010747)2.35507003
65Absence seizures (HP:0002121)2.32318767
66Congenital primary aphakia (HP:0007707)2.31451247
67Sacral dimple (HP:0000960)2.30066376
68Oligodactyly (hands) (HP:0001180)2.25950803
69Septo-optic dysplasia (HP:0100842)2.25778386
70Split foot (HP:0001839)2.24332598
71Hyperventilation (HP:0002883)2.23651367
72Fetal akinesia sequence (HP:0001989)2.22882523
73Abnormality of salivation (HP:0100755)2.22209984
74Elfin facies (HP:0004428)2.21685831
75Nephrogenic diabetes insipidus (HP:0009806)2.21431484
76Lower limb muscle weakness (HP:0007340)2.20917471
77Focal dystonia (HP:0004373)2.20743281
78Inability to walk (HP:0002540)2.20235577
79Vaginal atresia (HP:0000148)2.18941838
80High anterior hairline (HP:0009890)2.18260739
81Nephronophthisis (HP:0000090)2.18013987
82Depression (HP:0000716)2.17966818
83Spastic tetraplegia (HP:0002510)2.17625394
84Intestinal atresia (HP:0011100)2.17139532
85Amblyopia (HP:0000646)2.16880798
86Genital tract atresia (HP:0001827)2.16678255
87Absent speech (HP:0001344)2.16213116
88Generalized tonic-clonic seizures (HP:0002069)2.13890242
89Impaired vibration sensation in the lower limbs (HP:0002166)2.13737616
90Craniofacial dystonia (HP:0012179)2.13031372
91Optic nerve hypoplasia (HP:0000609)2.11800603
92Hypoplasia of the corpus callosum (HP:0002079)2.11169615
93Neoplasm of the adrenal cortex (HP:0100641)2.10704106
94Partial agenesis of the corpus callosum (HP:0001338)2.10219925
95Stereotypic behavior (HP:0000733)2.09460381
96True hermaphroditism (HP:0010459)2.08896100
97Action tremor (HP:0002345)2.06465250
98Molar tooth sign on MRI (HP:0002419)2.05708748
99Abnormality of midbrain morphology (HP:0002418)2.05708748
100Heterotopia (HP:0002282)2.04749214
101Sporadic (HP:0003745)2.02117655
102Spastic paraplegia (HP:0001258)2.00676217
103Anophthalmia (HP:0000528)2.00368640
104Dialeptic seizures (HP:0011146)2.00072125
105Overriding aorta (HP:0002623)1.99951952
106Pancreatic cysts (HP:0001737)1.98806930
107Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.96253766
108Short 4th metacarpal (HP:0010044)1.96253766
109Paraplegia (HP:0010550)1.96139898
110Oligodactyly (HP:0012165)1.95810993
111Pancreatic fibrosis (HP:0100732)1.95252872
112Abnormality of the motor neurons (HP:0002450)1.94407693
113Abnormal neuron morphology (HP:0012757)1.94407693
114Polymicrogyria (HP:0002126)1.93285612
115Type II lissencephaly (HP:0007260)1.91647473
116Exotropia (HP:0000577)1.91348144
117Atonic seizures (HP:0010819)1.90427388
118Renal hypoplasia (HP:0000089)1.89175706
119Open mouth (HP:0000194)1.88823871
120Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.88290968
121Degeneration of the lateral corticospinal tracts (HP:0002314)1.88290968
122Pheochromocytoma (HP:0002666)1.87885446
123Specific learning disability (HP:0001328)1.87739735
124Shoulder girdle muscle weakness (HP:0003547)1.87255063
125Trigonocephaly (HP:0000243)1.85688184
126Pointed chin (HP:0000307)1.85264752
127Failure to thrive in infancy (HP:0001531)1.84702832
128Esotropia (HP:0000565)1.84663413
129Gait imbalance (HP:0002141)1.84022228
130Febrile seizures (HP:0002373)1.83677733
131Megalocornea (HP:0000485)1.83118158
132Large eyes (HP:0001090)1.82275067
133Cutaneous finger syndactyly (HP:0010554)1.80788480
134Poor suck (HP:0002033)1.80581847
135Narrow forehead (HP:0000341)1.79683978
136Anencephaly (HP:0002323)1.78345201
137Morphological abnormality of the middle ear (HP:0008609)1.76368309
138Postaxial hand polydactyly (HP:0001162)1.76168342
139Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75949431
140Patellar aplasia (HP:0006443)1.75209361
141Abnormality of the 4th metacarpal (HP:0010012)1.74714588
142Poor coordination (HP:0002370)1.73803312
143Intellectual disability, moderate (HP:0002342)1.72929497
144Optic nerve coloboma (HP:0000588)1.72044173
145Micropenis (HP:0000054)1.71349114
146Rib fusion (HP:0000902)1.71048455
147Sclerocornea (HP:0000647)1.69140762
148Absent septum pellucidum (HP:0001331)1.68201738
149Abnormality of the renal medulla (HP:0100957)1.67428887
150Renal dysplasia (HP:0000110)1.65993043
151Chronic hepatic failure (HP:0100626)1.65456310
152Abnormality of the diencephalon (HP:0010662)1.65173475
153Abnormality of the aortic arch (HP:0012303)1.65122370

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK18.92632891
2MAP3K93.49220111
3DYRK23.25472964
4MINK12.78799792
5PHKG12.61201085
6PHKG22.61201085
7NTRK22.57598191
8LATS22.40552393
9MAP3K42.27337713
10ERBB32.20948632
11MAPK132.19129585
12KSR12.14407486
13SIK21.92518766
14PAK61.83825014
15MAP2K71.82084020
16NTRK31.79332703
17TRIM281.74617128
18EPHA31.68858666
19MAP4K21.65386081
20EPHB21.58334279
21DAPK21.55621975
22CSNK1G21.46716111
23LIMK11.38921229
24CDK51.29447719
25SIK31.29343642
26MARK21.23721353
27MAP2K41.22164301
28UHMK11.19641202
29CAMKK11.17294910
30PINK11.17110211
31CASK1.16078730
32TYRO31.13438692
33SRPK11.11559730
34PKN11.07297234
35BCR1.06230384
36CSNK1G31.05293318
37EPHA41.04275127
38DYRK1B1.00894223
39DYRK31.00189808
40NTRK11.00037483
41CDK180.99515322
42KSR20.98693586
43PAK30.98508533
44PNCK0.97163302
45ICK0.96165825
46CDK140.94332612
47TAOK10.93934716
48FGFR20.93481415
49DYRK1A0.93439886
50MAP3K120.92814083
51CDK150.92671189
52CSNK1A1L0.90320127
53RPS6KA20.90242674
54PLK20.87770997
55PRKCZ0.86594288
56RET0.86017911
57SCYL20.85360783
58CDK11A0.81983041
59PRKCG0.76012122
60TNIK0.75694069
61TESK10.74219699
62MAP2K60.72455134
63MAP3K60.68786570
64STK110.68772154
65DAPK10.66136279
66MAPK120.64563010
67MKNK20.64199876
68CCNB10.63701743
69ERBB20.63214846
70MKNK10.62435524
71CSNK1G10.62276613
72ALK0.61475848
73CAMK2B0.60856376
74PRKD30.60400644
75MAPK150.58801500
76MAP3K20.55363574
77CAMK1G0.55010471
78FYN0.53664746
79RIPK10.52654509
80GRK50.52287262
81PRKCI0.51850193
82INSRR0.51140875
83RPS6KA40.50845621
84BMPR1B0.50586479
85BCKDK0.50507000
86SGK20.50109115
87MAPK90.49895063
88WNK30.49411279
89CAMKK20.48141969
90PRPF4B0.46555933
91CAMK40.45972362
92ADRBK20.43607093
93WNK40.42259255
94NEK10.41600595
95EIF2AK20.40274072
96PRKCH0.40224392
97CAMK2A0.40107453
98CDC70.39942915
99CSNK1D0.38089490
100CAMK10.36897379
101BRD40.35725341
102CDK190.35395417
103PKN20.34853064
104PRKAA10.34597600
105CSNK1A10.34130051
106PRKACA0.33928599
107PRKACB0.33891599
108MAP3K100.33888487
109PRKDC0.33691943
110PRKCE0.32986241
111CDK30.31420524
112TESK20.29614104
113LMTK20.29314094
114SGK10.29046367
115PDGFRA0.28809225
116MAPK80.28767709
117RPS6KA30.27852635
118PRKG10.27802756
119ILK0.26589020
120IRAK20.25103662
121MAPK40.24840031
122CAMK1D0.23263391
123MAPK100.23146609
124RPS6KA10.23074333
125AURKA0.22713049
126GSK3B0.22663528
127CSNK1E0.22489746
128ROCK10.22058859
129ABL20.21657499
130SGK4940.21540743
131SGK2230.21540743

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047212.70812062
2Nicotine addiction_Homo sapiens_hsa050332.70645075
3* Axon guidance_Homo sapiens_hsa043602.62645459
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.49912114
5Circadian entrainment_Homo sapiens_hsa047132.27592004
6GABAergic synapse_Homo sapiens_hsa047272.23527836
7Dopaminergic synapse_Homo sapiens_hsa047282.23319792
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.10061963
9Olfactory transduction_Homo sapiens_hsa047402.09882989
10Glutamatergic synapse_Homo sapiens_hsa047242.09251455
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.05238561
12Cholinergic synapse_Homo sapiens_hsa047251.98400501
13Morphine addiction_Homo sapiens_hsa050321.97404663
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.94763457
15Long-term potentiation_Homo sapiens_hsa047201.88610465
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.85816387
17Gap junction_Homo sapiens_hsa045401.79898297
18Steroid biosynthesis_Homo sapiens_hsa001001.79034258
19Endometrial cancer_Homo sapiens_hsa052131.71454455
20Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.62985964
21Colorectal cancer_Homo sapiens_hsa052101.62440674
22Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.61842466
23Cocaine addiction_Homo sapiens_hsa050301.60412910
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58624568
25Amphetamine addiction_Homo sapiens_hsa050311.56152799
26Cardiac muscle contraction_Homo sapiens_hsa042601.54837892
27Serotonergic synapse_Homo sapiens_hsa047261.51632326
28ErbB signaling pathway_Homo sapiens_hsa040121.49027340
29Long-term depression_Homo sapiens_hsa047301.43517640
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.39997020
31Glioma_Homo sapiens_hsa052141.39138574
32Insulin secretion_Homo sapiens_hsa049111.38714225
33Oxytocin signaling pathway_Homo sapiens_hsa049211.38445111
34Estrogen signaling pathway_Homo sapiens_hsa049151.38368675
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.37380098
36Salivary secretion_Homo sapiens_hsa049701.35411899
37Renin secretion_Homo sapiens_hsa049241.32799105
38GnRH signaling pathway_Homo sapiens_hsa049121.31973290
39Type II diabetes mellitus_Homo sapiens_hsa049301.29385631
40Renal cell carcinoma_Homo sapiens_hsa052111.25189515
41Parkinsons disease_Homo sapiens_hsa050121.23551933
42Gastric acid secretion_Homo sapiens_hsa049711.23355398
43Melanogenesis_Homo sapiens_hsa049161.21462014
44Neurotrophin signaling pathway_Homo sapiens_hsa047221.20033732
45Oocyte meiosis_Homo sapiens_hsa041141.17034791
46Oxidative phosphorylation_Homo sapiens_hsa001901.15823997
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12817512
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08926677
49Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.08527532
50Viral myocarditis_Homo sapiens_hsa054161.08080801
51Taste transduction_Homo sapiens_hsa047421.07146354
52Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.07065454
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02571934
54VEGF signaling pathway_Homo sapiens_hsa043701.01490025
55Basal cell carcinoma_Homo sapiens_hsa052171.00805869
56Hippo signaling pathway_Homo sapiens_hsa043901.00331466
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.99098738
58mTOR signaling pathway_Homo sapiens_hsa041500.96035306
59Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.92560404
60Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.92433180
61cAMP signaling pathway_Homo sapiens_hsa040240.90822607
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90775283
63Wnt signaling pathway_Homo sapiens_hsa043100.90517877
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.88129030
65Choline metabolism in cancer_Homo sapiens_hsa052310.86963807
66Alcoholism_Homo sapiens_hsa050340.85813102
67Insulin signaling pathway_Homo sapiens_hsa049100.84963015
68Alzheimers disease_Homo sapiens_hsa050100.84670637
69Sphingolipid signaling pathway_Homo sapiens_hsa040710.84187383
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84134684
71Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.83741406
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83725595
73Huntingtons disease_Homo sapiens_hsa050160.82748036
74Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.82743461
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.81946251
76Hedgehog signaling pathway_Homo sapiens_hsa043400.79757947
77Ras signaling pathway_Homo sapiens_hsa040140.79226893
78MAPK signaling pathway_Homo sapiens_hsa040100.79221945
79Calcium signaling pathway_Homo sapiens_hsa040200.78819305
80Dorso-ventral axis formation_Homo sapiens_hsa043200.76890370
81cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76877258
82Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.73816917
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73086265
84Non-small cell lung cancer_Homo sapiens_hsa052230.71811852
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.70827908
86Endocytosis_Homo sapiens_hsa041440.69558235
87Ether lipid metabolism_Homo sapiens_hsa005650.68950039
88Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68393591
89Phototransduction_Homo sapiens_hsa047440.65217215
90Protein export_Homo sapiens_hsa030600.64386796
91AMPK signaling pathway_Homo sapiens_hsa041520.62649900
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.61970178
93Prion diseases_Homo sapiens_hsa050200.61618697
94Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61268946
95Rap1 signaling pathway_Homo sapiens_hsa040150.61262944
96Pancreatic cancer_Homo sapiens_hsa052120.59645842
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.58868650
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.58367032
99Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58097917
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.57733680
101Prolactin signaling pathway_Homo sapiens_hsa049170.56890601
102mRNA surveillance pathway_Homo sapiens_hsa030150.56874318
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55730319
104Butanoate metabolism_Homo sapiens_hsa006500.55626536
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.55062339
106Chronic myeloid leukemia_Homo sapiens_hsa052200.55042168
107Dilated cardiomyopathy_Homo sapiens_hsa054140.52836092
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51889797
109Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51817000
110Tight junction_Homo sapiens_hsa045300.50478006
111Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50394637
112Vibrio cholerae infection_Homo sapiens_hsa051100.50386630
113Basal transcription factors_Homo sapiens_hsa030220.48863022
114N-Glycan biosynthesis_Homo sapiens_hsa005100.47941896
115Fanconi anemia pathway_Homo sapiens_hsa034600.47496921
116Notch signaling pathway_Homo sapiens_hsa043300.46975469
117Glucagon signaling pathway_Homo sapiens_hsa049220.46613161
118Vascular smooth muscle contraction_Homo sapiens_hsa042700.44617359
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44236502
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41968827
121Collecting duct acid secretion_Homo sapiens_hsa049660.41028701
122Regulation of autophagy_Homo sapiens_hsa041400.40787723
123Circadian rhythm_Homo sapiens_hsa047100.38924893
124beta-Alanine metabolism_Homo sapiens_hsa004100.37758662
125RNA polymerase_Homo sapiens_hsa030200.33986020
126Linoleic acid metabolism_Homo sapiens_hsa005910.33898480
127Ovarian steroidogenesis_Homo sapiens_hsa049130.33457340
128Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32052933
129Thyroid hormone synthesis_Homo sapiens_hsa049180.28284981
130Propanoate metabolism_Homo sapiens_hsa006400.27895448

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